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Search Results for " lpa "

Targets Recommended: LPA Receptor LPA Receptor

80

抑制剂 & 化合物

14

天然产物

5

重组蛋白

3

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T23438	TC LPA5 4	LPA Receptor	GPCR/G Protein
	TC LPA5 4是LPA5受体的拮抗剂。
T15785	LPA1 receptor antagonist 1 LPA1 R antagonist 1	LPA Receptor	GPCR/G Protein
	LPA1 receptor antagonist 1(LPA1 R antagonist 1) 是一种具有选择性和高效性的溶血磷脂酸 (LPA1) 受体拮抗剂( IC50 : 25 nM)，可用于研究特发性肺纤维化。
T83879	1-Arachidoyl Lysophosphatidic Acid sodium 1-Arachidoyl LPA,LPA(20:0),1-Eicosanoyl-Lysophosphatidic Acid
	1-花生四烯酰基溶血磷脂酸（1-arachidoyl LPA）是溶血磷脂酸受体1（LPA1）的激动剂，并且是一种含有花生四烯酸的甘油磷脂，花生四烯酸位于sn-1位置。它能在主要表达LPA1而非LPA2-LPA6的人类肺成纤维细胞中诱导钙离子动员（EC50 = 3.6 µM）。在无细胞试验中，1-Arachidoyl LPA（2.5 µM）还能结合到过氧化物酶体增殖物激活受体γ（PPARγ）的配体结合域。人类尿液中也发现了该化合物。
T77789	Oleoyl-L-alpha-lysophosphatidic acid sodium salt LPA sodium salt	Others	Others
	Oleoyl-L-alpha-lysophosphatidic acid sodium salt为必需的细胞膜生物合成代谢物，可通过与G蛋白偶联受体（GPCR）（即LPA受体）相互作用来介导信号传导，是LPA1和LPA2受体的内源性激动剂。
T31101	CRT0273750 CRT 0273750,CRT-0273750	PDE	Metabolism
	CRT0273750 是一种 ATX 抑制剂的先导化合物，可调节血浆中 LPA 水平，用于 ATX/LPA 依赖性癌症模型。
T36907	1-Oleoyl Lysophosphatidic Acid Oleoyl-sn-3-Glycerophosphate,1-Oleoyl LPA,1-Oleoyl Lysophosphatidic Acid	Others	Others
	1-Oleoyl lysophosphatidic acid is a species of lysophosphatidic acid (LPA) containing oleic acid at the sn-1 position. Phosphatidic acid is produced either directly through the action of phospholipase D (PLD) or through a two step process involving liberation of diacylglycerol (DAG) by phospholipase C (PLC) followed by phosphorylation of DAG by diglycerol kinase.[1] Hydrolysis of the fatty acid at the sn-2 position by phospholipase A2 (PLA2) yields bioactive LPA. LPA binds to one of five differe...
T22834	H2L 5765834	LPA Receptor; LPL Receptor	GPCR/G Protein
	H2L 5765834 是溶血磷脂酸受体 LPA1、LPA3和 LPA5拮抗剂，IC50值分别为 94、752 和 463 nM。
T11533	Z-HA155 CS-963	PDE	Metabolism
	Z-HA155 (CS-963) 是一种高效的 ATX 选择性抑制剂，其 IC50=5.7 nM。
T21654	1-Oleoyl lysophosphatidic acid sodium 1-Oleoyl lysophosphatidic acid sodium salt	LPA Receptor	GPCR/G Protein
	1-Oleoyl lysophosphatidic acid sodium (1-Oleoyl lysophosphatidic acid sodium salt) salt 是 LPA1 和 LPA2 的内源性激动剂，可通过诱导 DNA 合成促进有丝分裂，参与正常和病理性情绪反应，如焦虑和抑郁。
T83772	1-Linoleoyl Lysophosphatidic Acid sodium 1-Linoleoyl-2-hydroxy-sn-glycero-3-PA,LPA(18:2),PA(18:2(9Z,12Z)/0:0),1-Octadecadienoyl-2-hydroxy-sn-glycero-3-phosphate,18:2 Lyso PA,1-Octadecadienoyl-2-hydroxy-sn-glycero-3-PA,PA(18:2/0:0),1-Linoleoyl-2-hydroxy-sn-glycero-3-phosphate,1-Linoleoyl LPA
	1-Linoleoyl LPA（1-亚油酰LPA）是LPA2受体的激动剂，属于一种含有亚油酸的甘油磷脂，在sn-1位置含亚油酸。它是小鼠和人体血浆中最丰富的LPA。1-Linoleoyl LPA在表达LPA2受体的Sf9细胞中选择性地增加细胞内钙水平（EC50约为10 nM），相较于表达LPA1和LPA3受体的Sf9细胞（EC50分别约为200和80 nM）。携带NCTC克隆2472肿瘤的小鼠中，1-linoleoyl LPA的血清水平增加。与患有初发进行性多发性硬化症的患者相比，复发缓解型多发性硬化症患者的血浆1-Linoleoyl LPA水平降低，且与神经功能缺损严重程度负相关。
T15786	LPA2 antagonist 1	Hydroxylase	Metabolism
	LPA2 antagonist 1 is an LPA2 antagonist (IC50: 17 nM).
T11875	LPA2 antagonist 2	LPA Receptor	GPCR/G Protein
	LPA2 antagonist 2 is ＞480-fold more selective than LPA3 (IC50 of 13.85 μM).LPA2 antagonist 2 is a selective LPA2 antagonist with an IC50 of 28.3 nM and a Ki of 21.1 nM.
T63231	LPA5 antagonist 1	Others	Others
	LPA5 antagonist 1 是选择性的、强效的 lysophosphatidic acid receptor 5(LPA5) 拮抗剂，IC50 值为32 nM。LPA5 antagonist 1 具有高脑渗透性和抗痛活性，能够用于研究炎症性和神经性疼痛。
T63172	LPA5 antagonist 2	Others	Others
	LPA5 antagonist 2 (compound 65) 是一种高水溶性的 LPA5 拮抗剂，可明显减轻痛觉。LPA5 antagonist 2 能够用于研究炎症性和神经性疼痛。
T1606	Fasudil HA-1077,AT877,法舒地尔	ROCK; Serine/threonin kinase; Calcium Channel; PKA; PKC; Autophagy	Autophagy; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; Membrane transporter/Ion channel; Metabolism; Stem Cells; Tyrosine Kinase/Adaptors
	Fasudil (HA-1077) 是一种非特异性 RhoA/ROCK 抑制剂，也是 Ca2+通道拮抗剂和血管扩张剂。它对蛋白激酶有抑制作用，ROCK1 的 Ki 值为 0.33 μM，ROCK2 和 PKA、PKC、PKG 的 IC50值分别 0.158 μM 和 4.58 μM、12.30 μM、1.650 μM。
T3060	Fasudil hydrochloride Fasudil (HA-1077) HCl,盐酸法舒地尔,HA-1077,Fasudil HCl,HA-1077 hydrochloride,AT-877	ROCK; Serine/threonin kinase; Calcium Channel; HIV Protease; PKA; PKC; Autophagy	Autophagy; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Proteases/Proteasome; Stem Cells; Tyrosine Kinase/Adaptors
	Fasudil hydrochloride (HA-1077) 是一种非特异性RhoA/ROCK 抑制剂，也抑制蛋白激酶，对 ROCK1、PKA、PKC 和 MLCK 的 Ki 值分别为 0.33 μM、1.0 μM、9.3 μM 和 55 μM。
TP2056L	Acetyl-Calpastatin (184-210)(human) acetate Acetyl-Calpastatin (184-210) (human) acetate(123714-50-1 Free base )	Cysteine Protease	Proteases/Proteasome
	Acetyl-Calpastatin (184-210)(human) acetate 是一种有效，选择性和可逆的钙蛋白酶 (calpain) 抑制剂，对 μ-钙蛋白酶和组织蛋白酶 L 的 Ki 值分别为 0.2 nM 和 6 μM。
T4628	Seladelpar MBX 8025	PPAR	DNA Damage/DNA Repair; Metabolism
	Seladelpar (MBX 8025) 是一种有效的，具有口服活性的，特异性PPAR-δ激动剂，EC50为 2 nM。
T5670	Isobutylparaben	Others; Antibacterial	Microbiology/Virology; Others
	Isobutylparaben 是组成型雄烷受体激活剂，是一种广谱抗菌剂，用于个人护理产品和化妆品中。
T39516	Bocidelpar	PPAR	DNA Damage/DNA Repair; Metabolism
	Bocidelpar 是一种有效的过氧化物酶体增殖物激活受体 delta 调节剂，可改善杜兴肌营养不良肌肉细胞中的线粒体生物合成和功能。
T12527L	Mavodelpar free acid hydrochloride Mavodelpar free acid hydrochloride(942594-93-6 Free base),Pparδ agonist HCl,HPP593 free acid HCl,REN001 free acid HCl	PPAR	DNA Damage/DNA Repair; Metabolism
	Mavodelpar free acid hydrochloride (Pparδ agonist HCl) 是一种有效的 PPARδ激动剂。
T5686	Isopropylparaben	Others	Others
	Isopropylparaben 是一种防腐剂和防腐杀虫剂。
T4165	Delpazolid LCB01-0371	Antibacterial; Antibiotic	Microbiology/Virology
	Delpazolid (LCB01-0371) 是一种恶唑烷酮类新型抗生素，能抑制MSSA 和MRSA 的生长，对它们的MIC90值都为 2 μg/mL。
T3334	Velpatasvir GS-5816,维帕他韦	HCV Protease; SARS-CoV	Microbiology/Virology; Proteases/Proteasome
	Velpatasvir (GS-5816) 是一种的 HCV NS5A 抑制剂。它也是 SARS-CoV 3CLpro 的抑制剂，IC50为 2.16 μM。
T75794	Acetyl-Calpastatin(184-210)(human) TFA
	Acetyl-Calpastatin(184-210)(human) TFA 是一种有效，选择性和可逆的钙蛋白酶 (calpain) 抑制剂，对 μ-钙蛋白酶和组织蛋白酶 L 的Ki 值分别为 0.2 nM 和 6 μM。
TP2056	Acetyl-Calpastatin(184-210)(human) Acetyl-Calpastatin (184-210) (human)
	Selective calpain inhibitor. Strongly inhibits calpain I (Ki = 0.2 nM) and II but does not inhibit papain, trypsin and cathepsin L (Ki = 6 μM). Increases secretion of amyoid β-protein (Aβ) 42, Aβ40 and Aβ42 ratio.
TP2380	Elpamotide
	Elpamotide is a vaccine consisting of a VEGFR2-169 peptide.
T80531	Ac-AAVALLPAVLLALLAP-DEVD-CHO DEVD-CHO-CPP 32	Caspase	Apoptosis; Proteases/Proteasome
	DEVD-CHO-CPP 32（Ac-AAVALLPAVLLALLAP-DEVD-CHO）是一种高效且可逆的caspase-3抑制剂。
T80537	Ac-AAVALLPAVLLALLAP-LEHD-CHO	Caspase	Apoptosis; Proteases/Proteasome
	Ac-AAVALLPAVLLALLAP-LEHD-CHO 是半胱天冬酶4、5和9的抑制剂，能够对Neocarzinostatin处理的MCF-7细胞展现保护效果。
T126544	3-O-Acetylpadmatin	Others	Others
	3-O-Acetylpadmatin 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T126544，CAS号为 100595-93-5。
T21949	Calpain Inhibitor XII	Others	Others
	(Rac)-Calpain Inhibitor XII是一种可逆的，选择性抑制钙蛋白酶I（calpain I; μ-calpain）的化合物，具有19 nM的Ki值。其对钙蛋白酶II（calpain II; m-calpain; Ki=120 nM）和组织蛋白酶B（cathepsin B; Ki=750 nM）显示出较低的抑制亲和力。(Rac)-Calpain Inhibitor XII用于研究钙蛋白酶在多种生理过程中的角色，如嗜中性粒细胞趋化性、神经元信号传导和心脏对损伤的响应。
T38931	Calpain Inhibitor-1	Others	Others
	Calpain Inhibitor-1 (compound 36) is a highly potent and selective inhibitor of Calpain 1 (Cal1), which is a cysteine protease. It exhibits an IC50 value of 100 nM and a Ki value of 2.89 μM.
T25076	Amelparib JPI289,JPI-289,JPI 289	Others	Others
	Amelparib (JPI-289) is an inhibitor of the poly-ADP-ribose polymerase.
T26182	Seladelpar lysine MBX-8025 lysine dihydrate,MBX-8025 Lysine,MBX 8025 Lysine MBX8025 Lysine	Others	Others
	Seladelpar lysine, a selective PPAR-δ agonist, is used for the therapy of Homozygous Familial Hypercholesterolemia (HoFH).
T80241	Calpastatin subdomain B	Proteasome	Proteases/Proteasome; Ubiquitination
	Calpastatin subdomain B为具有生物活性的肽，其作用为抑制钙蛋白酶活性。
T80551	Calpain inhibitor V Mu-Val-HPh-FMK	Antibiotic	Microbiology/Virology
	Calpain inhibitor V (Mu-Val-HPh-FMK) 为具抗衣原体活性的细胞渗透性不可逆钙蛋白酶抑制剂。
T12876	Seladelpar sodium salt RWJ-800025 sodium salt,MBX-8025 sodium salt	Others	Others
	Seladelpar sodium salt (MBX-8025) 是一种具有口服活性、有效且特异性的PPARδ激动剂，EC50值为 2 nM。它对 PPARδ 的选择性分别是对 PPARα 和 PPARγ 的 750 和 2500 多倍。
T63391	Calpain Inhibitor-2	Others	Others
	Calpain Inhibitor-2 是具有亲脂性的钙蛋白酶抑制剂，与黑色素瘤细胞系（A-375和B-16F1）和PC-3前列腺癌细胞相比，他们在体外具有中等到良好的抗增殖效果。Calpain Inhibitor-2 中的化合物3，在基质胶细胞侵袭测定中以2μM 浓度能够抑制了80%的DU-145细胞侵袭。
T71638	Isomolpan hydrochloride	Others	Others
	Isomolpan hydrochloride is a dopamine receptor D2 agonist.
T84437	Ac-Calpastatin (184-210) Calpastatin Peptide B27-WT	Others	Others
	Calpastatin (184-210), an acetylated synthetic peptide derived from human calpastatin, effectively inhibits the calcium-dependent cysteine proteases, calpain I (µ-calpain) and calpain II (m-calpain), which require micromolar and millimolar calcium concentrations, respectively. Unlike its action on calpains, this 27 amino acid peptide does not inhibit papain (a cysteine protease) or trypsin (a serine protease). Encoded by exon 1B of Ac-calpastatin (184-210), it aligns with a section of inhibitory...
T77140	Ralpancizumab
	Ralpancizumab 是一种 PCSK9选择性抑制剂，在出血性中风中有潜在应用。
T15336	Fonadelpar NPS-005,SJP-0035	PPAR	DNA Damage/DNA Repair; Metabolism
	Fonadelpar is an agonist of PPARδ. It also is used in the research of neuroparalytic keratopathy.
T33793	Olpadronic acid Me2 APD,Me2-APD,Me2APD	Others	Others
	Olpadronic acid is a biochemical.
T72439	Calpain Inhibitor XI	Others	Others
	Calpain Inhibitor XI，一种可逆的calpain-1共价抑制剂，适用于神经退行性疾病的研究。
T125997	17-Methylparsonsianidine	Others	Others
	17-Methylparsonsianidine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T125997。
T75158	Olpasiran	Others	Others
	Olpasiran 是一种siRNA，可减少肝脏中脂蛋白 lipoprotein(a) 的合成。
T20590	Zilpaterol hydrochloride	Others	Others
	Zilpaterol hydrochloride is a agonist of β-adrenergic receptor (AR). It is used to increase the feeding efficiency and the size of cattle.
T77157	Dilpacimab
	Dilpacimab (ABT165) 是一种有效的双可变结构域免疫球蛋白，靶向 delta 样配体 4 (DLL4) 和VEGF 通路。Dilpacimab 可用于癌症研究。
T31370	Delparantag PMX60056,PMX-60056,PMX 60056
	Delparantag( PMX-60056) is a heparins antidote designed to restore coagulation.
T80532	Ac-AAVALLPAVLLALLAP-YVAD-CHO	Caspase	Apoptosis; Proteases/Proteasome
	Ac-AAVALLPAVLLALLAP-YVAD-CHO为具备细胞穿透能力的caspase-1抑制剂，展现出抗肿瘤活性。

化合物

Cat.No: T23438

Target: LPA Receptor

LPA1 receptor antagonist 1

Cat.No: T15785

Synonym: LPA1 R antagonist 1

Target: LPA Receptor

1-Arachidoyl Lysophosphatidic Acid sodium

Cat.No: T83879

Synonym: 1-Arachidoyl LPA,LPA(20:0),1-Eicosanoyl-Lysophosphatidic Acid

Oleoyl-L-alpha-lysophosphatidic acid sodium salt

Cat.No: T77789

Synonym: LPA sodium salt

Target: Others

Cat.No: T31101

Synonym: CRT 0273750,CRT-0273750

Target: PDE

1-Oleoyl Lysophosphatidic Acid

Cat.No: T36907

Synonym: Oleoyl-sn-3-Glycerophosphate,1-Oleoyl LPA,1-Oleoyl Lysophosphatidic Acid

Target: Others

Cat.No: T22834

Target: LPA Receptor, LPL Receptor

Cat.No: T11533

Synonym: CS-963

Target: PDE

1-Oleoyl lysophosphatidic acid sodium

Cat.No: T21654

Synonym: 1-Oleoyl lysophosphatidic acid sodium salt

Target: LPA Receptor

1-Linoleoyl Lysophosphatidic Acid sodium

Cat.No: T83772

Synonym: 1-Linoleoyl-2-hydroxy-sn-glycero-3-PA,LPA(18:2),PA(18:2(9Z,12Z)/0:0),1-Octadecadienoyl-2-hydroxy-sn-glycero-3-phosphate,18:2 Lyso PA,1-Octadecadienoyl-2-hydroxy-sn-glycero-3-PA,PA(18:2/0:0),1-Linoleoyl-2-hydroxy-sn-glycero-3-phosphate,1-Linoleoyl LPA

LPA2 antagonist 1

Cat.No: T15786

Target: Hydroxylase

LPA2 antagonist 2

Cat.No: T11875

Target: LPA Receptor

LPA5 antagonist 1

Cat.No: T63231

Target: Others

LPA5 antagonist 2

Cat.No: T63172

Target: Others

Cat.No: T1606

Synonym: HA-1077,AT877,法舒地尔

Target: ROCK, Serine/threonin kinase, Calcium Channel, PKA, PKC, Autophagy

Fasudil hydrochloride

Cat.No: T3060

Synonym: Fasudil (HA-1077) HCl,盐酸法舒地尔,HA-1077,Fasudil HCl,HA-1077 hydrochloride,AT-877

Target: ROCK, Serine/threonin kinase, Calcium Channel, HIV Protease, PKA, PKC, Autophagy

Acetyl-Calpastatin (184-210)(human) acetate

Cat.No: TP2056L

Synonym: Acetyl-Calpastatin (184-210) (human) acetate(123714-50-1 Free base )

Target: Cysteine Protease

Cat.No: T4628

Synonym: MBX 8025

Target: PPAR

Isobutylparaben

Cat.No: T5670

Target: Others, Antibacterial

Cat.No: T39516

Target: PPAR

Mavodelpar free acid hydrochloride

Cat.No: T12527L

Synonym: Mavodelpar free acid hydrochloride(942594-93-6 Free base),Pparδ agonist HCl,HPP593 free acid HCl,REN001 free acid HCl

Target: PPAR

Isopropylparaben

Cat.No: T5686

Target: Others

Cat.No: T4165

Synonym: LCB01-0371

Target: Antibacterial, Antibiotic

Cat.No: T3334

Synonym: GS-5816,维帕他韦

Target: HCV Protease, SARS-CoV

Acetyl-Calpastatin(184-210)(human) TFA

Cat.No: T75794

Acetyl-Calpastatin(184-210)(human)

Cat.No: TP2056

Synonym: Acetyl-Calpastatin (184-210) (human)

Cat.No: TP2380

Ac-AAVALLPAVLLALLAP-DEVD-CHO

Cat.No: T80531

Synonym: DEVD-CHO-CPP 32

Target: Caspase

Ac-AAVALLPAVLLALLAP-LEHD-CHO

Cat.No: T80537

Target: Caspase

3-O-Acetylpadmatin

Cat.No: T126544

Target: Others

Calpain Inhibitor XII

Cat.No: T21949

Target: Others

Calpain Inhibitor-1

Cat.No: T38931

Target: Others

Cat.No: T25076

Synonym: JPI289,JPI-289,JPI 289

Target: Others

Seladelpar lysine

Cat.No: T26182

Synonym: MBX-8025 lysine dihydrate,MBX-8025 Lysine,MBX 8025 Lysine MBX8025 Lysine

Target: Others

Calpastatin subdomain B

Cat.No: T80241

Target: Proteasome

Calpain inhibitor V

Cat.No: T80551

Synonym: Mu-Val-HPh-FMK

Target: Antibiotic

Seladelpar sodium salt

Cat.No: T12876

Synonym: RWJ-800025 sodium salt,MBX-8025 sodium salt

Target: Others

Calpain Inhibitor-2

Cat.No: T63391

Target: Others

Isomolpan hydrochloride

Cat.No: T71638

Target: Others

Ac-Calpastatin (184-210)

Cat.No: T84437

Synonym: Calpastatin Peptide B27-WT

Target: Others

Cat.No: T77140

Cat.No: T15336

Synonym: NPS-005,SJP-0035

Target: PPAR

Olpadronic acid

Cat.No: T33793

Synonym: Me2 APD,Me2-APD,Me2APD

Target: Others

Calpain Inhibitor XI

Cat.No: T72439

Target: Others

17-Methylparsonsianidine

Cat.No: T125997

Target: Others

Cat.No: T75158

Target: Others

Zilpaterol hydrochloride

Cat.No: T20590

Target: Others

Cat.No: T77157

Cat.No: T31370

Synonym: PMX60056,PMX-60056,PMX 60056

Ac-AAVALLPAVLLALLAP-YVAD-CHO

Cat.No: T80532

Target: Caspase

Cat. No.	Product Name	Target	Signaling Pathways
T0834	Ethylparaben Ethyl 4-hydroxybenzoate,Ethyl parahydroxybenzoate,羟苯乙酯,尼泊金乙酯	Antibacterial; Antifungal	Microbiology/Virology
	Ethylparaben (Ethyl parahydroxybenzoate) 是一种标准化的化学过敏原。对羟基苯甲酸乙酯的生理作用是通过增加组胺释放和细胞介导免疫来实现的。
T3S2105	N-Benzylpalmitamide Macamide 1,玛卡酰胺 B,N-苄基十六烷酰胺,N-Benzylhexadecanamide	Others; FAAH; Autophagy	Autophagy; Metabolism; Neuroscience; Others
	N-Benzylpalmitamide (Macamide 1) 是从玛卡中得到的一种生物碱，可以时间依赖性方式抑制脂肪酸酰胺水解酶，有治疗疼痛、炎症和中枢神经系统退行性疾病的研究潜力。
T5557	Propylparaben 羟苯丙酯,Propyl 4-hydroxybenzoate,尼泊金丙酯,Propyl parahydroxybenzoate	Apoptosis; Endogenous Metabolite; Antibacterial	Apoptosis; Metabolism; Microbiology/Virology
	Propylparaben (Propyl parahydroxybenzoate) 是一种由植物和细菌产生的抗菌防腐剂。它普遍用于化妆品，药品和食品中。它通过改变细胞周期，细胞凋亡和类固醇生成途径来破坏卵泡的生长和类固醇生成功能。它还可降低大鼠的精子数量和活动能力。
T6S1652	Benzoylpaeoniflorin	COX	Immunology/Inflammation; Neuroscience
	Benzoylpaeoniflorin 是一种从白芍中提取的天然化合物，可以降低细胞凋亡，对冠心病具有潜在的研究价值。
TN1067	Galloylpaeoniflorin 6'-O-Galloyl paeoniflorin,没食子酰芍药苷	NF-κB; Androgen Receptor; ROS	Endocrinology/Hormones; Immunology/Inflammation; NF-κB
	Galloylpaeoniflorin (6'-O-Galloyl paeoniflorin) 是 NF-κB 抑制剂，同时也是 DNA 裂解抑制剂。
T0927	Butylparaben Butyl 4-hydroxybenzoate,Butyl parahydroxybenzoate,尼泊金丁酯,对羟基苯甲酸丁酯	Endogenous Metabolite; Antibacterial; Antibiotic	Metabolism; Microbiology/Virology
	Butylparaben (Butyl 4-hydroxybenzoate) 是一种标准化的化学过敏原，可增加组胺释放和细胞介导的免疫。
TN4688	O-Methylpallidine	Others	Others
	O-Methylpallidine是一种天然产物，属于番荔枝科索木属，其产品编号为 TN4688，CAS号为 27510-33-4。O-Methylpallidine可用作对照参考。
T82594	Debenzoylpaeoniflorgenin
	Debenzoylpaeoniflorgenin是从Paeonia lactiflora中分离得到的天然化合物，该植物是Guizhitang的一个组成成份。
TN2416	8-Debenzoylpaeoniflorin	Others	Others
	8-Debenzoylpaeoniflorin is a natural product from plants
TN5857	Debenzoylgalloylpaeoniflorin
	Debenzoylgalloylpaeoniflorin 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5857，CAS号为 262350-51-6。
T83310	4-O-Methyldebenzoylpaeoniflorin
	4-O-Methyldebenzoylpaeoniflorin为自Paeonia albiflora提取的自然化合物。
T40442	Propylparaben sodium Propyl4-hydroxybenzoatesodium,羟苯丙酯钠,Propylparahydroxybenzoatesodium	Others	Others
	Propylparaben sodium (propyl parahydroxybenzoate) is a naturally occurring antimicrobial preservative found in plants and bacteria. Widely utilized in cosmetics, pharmaceuticals, and foods, this compound impairs antral follicle growth and steroidogenic function by modifying the cell-cycle, apoptosis, and steroidogenesis pathways. Additionally, propylparaben sodium reduces sperm count and motility in rats.
TN3607	Catalpalactone	cAMP	GPCR/G Protein
	Catalpalactone exhibits high antitermitic, and cytotoxic activities, it exhibits potent inhibitory effects on lipopolysaccharide-induced NO synthesis in RAW 264.7 cells , with IC50 values of 9.80 microM. Catalpalactone can inhibit dopamine biosynthesis by
TN5855	2'-O-Benzoylpaeoniflorin
	2'-O-Benzoylpaeoniflorin 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5855，CAS号为 1456598-64-3。

天然产物

Cat.No: T0834

Synonym: Ethyl 4-hydroxybenzoate,Ethyl parahydroxybenzoate,羟苯乙酯,尼泊金乙酯

Target: Antibacterial, Antifungal

N-Benzylpalmitamide

Cat.No: T3S2105

Synonym: Macamide 1,玛卡酰胺 B,N-苄基十六烷酰胺,N-Benzylhexadecanamide

Target: Others, FAAH, Autophagy

Cat.No: T5557

Synonym: 羟苯丙酯,Propyl 4-hydroxybenzoate,尼泊金丙酯,Propyl parahydroxybenzoate

Target: Apoptosis, Endogenous Metabolite, Antibacterial

Benzoylpaeoniflorin

Cat.No: T6S1652

Target: COX

Galloylpaeoniflorin

Cat.No: TN1067

Synonym: 6'-O-Galloyl paeoniflorin,没食子酰芍药苷

Target: NF-κB, Androgen Receptor, ROS

Cat.No: T0927

Synonym: Butyl 4-hydroxybenzoate,Butyl parahydroxybenzoate,尼泊金丁酯,对羟基苯甲酸丁酯

Target: Endogenous Metabolite, Antibacterial, Antibiotic

O-Methylpallidine

Cat.No: TN4688

Target: Others

Debenzoylpaeoniflorgenin

Cat.No: T82594

8-Debenzoylpaeoniflorin

Cat.No: TN2416

Target: Others

Debenzoylgalloylpaeoniflorin

Cat.No: TN5857

4-O-Methyldebenzoylpaeoniflorin

Cat.No: T83310

Propylparaben sodium

Cat.No: T40442

Synonym: Propyl4-hydroxybenzoatesodium,羟苯丙酯钠,Propylparahydroxybenzoatesodium

Target: Others

Cat.No: TN3607

Target: cAMP

2'-O-Benzoylpaeoniflorin

Cat.No: TN5855

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00611	SFP Protein, B.subtilis, Recombinant (His) Surfactin synthase-activating enzyme,sfp,lpa-8,4'-p...	Bacillus subtilis	E. coli
	The Bacillus subtilis enzyme Sfp, required for production of the lipoheptapeptide antibiotic surfactin, posttranslationally phosphopantetheinylates a serine residue in each of the seven peptidyl carrier protein domains of the first three subunits (SrfABC) of surfactin synthetase to yield docking sites for amino acid loading and peptide bond formation.
TMPY-04124	LPAL2 Protein, Human, Recombinant (mFc) APOARGC,APOAL,lipoprotein, Lp(a)-like 2, pseudogene,LPA<...	Human	HEK293 Cells
	LPAL2 (Lipoprotein(A) Like 2, Pseudogene) is a Pseudogene. This gene is similar to the lipoprotein, Lp(a) gene, but all transcripts produced by this gene contain a truncated open reading frame and are candidates for nonsense-mediated decay. Lipoprotein(a) [Lp(a)] level is an established risk factor for coronary artery disease and has been implicated in carotid artery disease (CAAD). Mutations in the solute carrier family 22 member 3 (SLC22A3), lipoprotein (a)-like 2 (LPAL2), and the lipoprotein ...
TMPH-02381	slpA Protein, Lactobacillus acidophilus, Recombinant (His & Myc) slpA,S-layer protein,Surface layer protein	Lactobacillus acidophilus	E. coli
	The S-layer is a paracrystalline mono-layered assembly of proteins which coat the surface of bacteria.
TMPH-00556	1-AGPAT Protein, E. coli, Recombinant (His) 1-AGP acyltransferase,1-AGPAT,LPAAT,1-acyl-sn-glyce...	E. coli	P. pastoris (Yeast)
	Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the 2 position. This enzyme can utilize either acyl-CoA or acyl-ACP as the fatty acyl donor. 1-AGPAT Protein, E. coli, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 29.5 kDa and the accession number is P26647.
TMPH-00433	Ex-FABP Protein, Coturnix coturnix japonica, Recombinant (His & Myc) Extracellular fatty acid-binding protein,Lipocalin Q83	Coturnix coturnix japonica	E. coli
	Siderocalin-like lipocalin tightly binding a variety of bacterial ferric siderophores, also binds long-chain unsaturated fatty acids such as linoleic acid, oleic acid, arachidonic acid and, with a lower affinity, long chain saturated fatty acids such as steraic acid. May act as an antibacterial factor, through dual ligand specificity, both as a siderophore-sequestrating molecule and a lysophosphatidic acid (LPA) sensor. Ex-FABP Protein, Coturnix coturnix japonica, Recombinant (His & Myc) is expr...

重组蛋白

SFP Protein, B.subtilis, Recombinant (His)

Cat.No: TMPJ-00611

Species: Bacillus subtilis

Expression System: E. coli

LPAL2 Protein, Human, Recombinant (mFc)

Cat.No: TMPY-04124

Species: Human

Expression System: HEK293 Cells

slpA Protein, Lactobacillus acidophilus, Recombinant (His & Myc)

Cat.No: TMPH-02381

Species: Lactobacillus acidophilus

Expression System: E. coli

1-AGPAT Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00556

Species: E. coli

Expression System: P. pastoris (Yeast)

Ex-FABP Protein, Coturnix coturnix japonica, Recombinant (His & Myc)

Cat.No: TMPH-00433

Species: Coturnix coturnix japonica

Expression System: E. coli

Cat. No.	Product Name	Target	Signaling Pathways
TMID-0173	Propylparaben-d4
	Propylparaben-d4 是 Propylparaben 的氘代化合物。Propylparaben 的 CAS 号为 94-13-3。Propylparaben 是一种由植物和细菌产生的抗菌防腐剂。它普遍用于化妆品，药品和食品中。它通过改变细胞周期，细胞凋亡和类固醇生成途径来破坏卵泡的生长和类固醇生成功能。它还可降低大鼠的精子数量和活动能力。
TMIH-0611	R-Zilpaterol-d7
	R-Zilpaterol-d7 是 R-Zilpaterol 的氘代化合物。
TMIH-0612	S-Zilpaterol-d7
	S-Zilpaterol-d7 是 S-Zilpaterol 的氘代化合物。

同位素标记化合物

Propylparaben-d4

Cat.No: TMID-0173

R-Zilpaterol-d7

Cat.No: TMIH-0611

S-Zilpaterol-d7

Cat.No: TMIH-0612

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