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Search Results for " loxl1 "
Targets Recommended: Lipoxygenase

3

抑制剂 & 化合物

3

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T60438L PXS-6302 hydrochloride

PXS-6302 hydrochloride (2584947-54-4 Free base)

Lipoxygenase Metabolism
PXS-6302 hydrochloride 是一种有效的不可逆赖氨酸氧化酶 (LOX) 抑制剂,对 Bovine LOX、rh LOXL1、 rh LOXL2、rh LOXL3 和 rh LOXL4 具有抑制作用, IC50 分别为 3.7 μM ,3.4 μM ,0.4 μM ,1.5 μM,0.3 μM。PXS-6302 hydrochloride 易透过皮肤,能够减少胶原蛋白堆积,显著改善疤痕外观。
T60296 PXS-4787

Others Others
PXS-4787 is a potent and selective inhibitor of lysyl oxidase (LOX) with broad-spectrum activity. It effectively suppresses lysyl oxidase activity by acting on its mechanisms. The compound displays inhibitory effects with IC50 values of 2 μM (Bovine LOX), 3.2 μM (rh LOXL1), 0.6 μM (rh LOXL2), 1.4 μM (rh LOXL3), and 0.2 μM (rh LOXL4), respectively [1].
T60438 PXS-6302

Others Others
PXS-6302 是不可逆的赖氨酸氧化酶 (LOX) 抑制剂,对Bovine LOX、rh LOXL1、rh LOXL2、rh LOXL3、rh LOXL4的IC50分别为 3.7 μM,3.4 μM,0.4 μM,1.5 μM 和0.3 μM。PXS-6302 可以轻松渗透皮肤,减少胶原蛋白沉积和交联,显着改善疤痕外观而不降低组织强度。 PXS-6302 在其他纤维化疾病中也可能有更广泛的应用。

化合物

PXS-6302 hydrochloride
Cat.No: T60438L
Synonym: PXS-6302 hydrochloride (2584947-54-4 Free base)
Target: Lipoxygenase
PXS-4787
Cat.No: T60296
Synonym:
Target: Others
PXS-6302
Cat.No: T60438
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPH-01628 LOXL1 Protein, Human, Recombinant

Lysyl oxidase-like protein 1,Lysyl oxidase homolog ...

Human E. coli
Active on elastin and collagen substrates. LOXL1 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 53.0 kDa and the accession number is Q08397.
TMPH-01629 LOXL1 Protein, Human, Recombinant (His)

Lysyl oxidase-like protein 1,LOXL1

Human E. coli
Active on elastin and collagen substrates.
TMPY-00203 LOXL2 Protein, Mouse, Recombinant (His)

1110004B06Rik,4930526G1<...

Mouse HEK293 Cells
Lysyl oxidase homolog 2, also known as Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, Lysyl oxidase-related protein WS9-14 and LOXL2, is a secreted protein that belongs to the lysyl oxidase family. LOXL2 contains four SRCR domains. The lysyl oxidase family is made up of five members: lysyl oxidase (LOX) and lysyl oxidase-like 1-4 ( LOXL1, LOXL2, LOXL3, LOXL4 ). All members share conserved C-terminal catalytic domains that provide for lysyl oxidase or lysyl oxidase-like enzyme act...

重组蛋白

LOXL1 Protein, Human, Recombinant
Cat.No: TMPH-01628
Species: Human
Expression System: E. coli
LOXL1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01629
Species: Human
Expression System: E. coli
LOXL2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00203
Species: Mouse
Expression System: HEK293 Cells
TargetMol Loading
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