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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T38312 |
L-Cysteine-glutathione disulfide
|
Others | Others |
L-Cysteine-glutathione disulfide, a glutathione derivative endogenous to mammalian cells, is comprised of the oxidized form of free glutathione tripeptide linked via a disulfide bond to L-cysteine. It has been shown to protect mice against acetaminophen-induced hepatotoxicity. | |||
T24018 |
D-Ribose-L-cysteine
DRiboseLcysteine,Ribcys,Riboceine,J424.013H,D Ribose L cysteine |
Others | Others |
D-Ribose-L-cysteine is the antioxidant glutathione precursor. | |||
T33813 |
Ophthalmic acid
|
Others | Others |
Ophthalmic acid is a glutathione analog in which cysteine is substituted by L-aminobutyrate. | |||
T83898 |
S-(N-Methylsulfinylbutylthiocarbamoyl)-L-cysteine
SFN-Cys,D,L-Sulforaphane-L-cysteine |
Others | Others |
S-(N-Methylsulfinylbutylthiocarbamoyl)-L-cysteine (SFN-Cys) 是一种异硫氰酸酯衍生物及第一类和第二类组蛋白去乙酰化酶(HDAC)抑制剂和抗癌剂硫代硫酸烯醇醚的活性代谢产物。它通过巯基乙酸途径酶从硫代硫酸烯醇醚经DL-硫代硫酸烯醇醚谷胱甘肽和硫代硫酸烯醇醚半胱氨酸甘肽中间体形成。SFN-Cys (20 µM) 通过创伤愈合和腔室分析实验,分别减少了U87MG和U373 MG胶质母细胞瘤细胞的侵袭和迁移。在45 µM的浓度下,它降低了对紫杉醇耐药的A549肺癌细胞(A549/T)中的α-微管蛋白、βIII-微管蛋白、司他敏1和X连锁抑制剂的凋亡(XIAP)的水平,并减少了细胞密度。使用30 µM浓度的SFN-Cys诱导U87MG和U373 MG细胞凋亡和G2/M期细胞周期停滞。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T2O2721 |
L-Cysteine
Thioserine,L-半胱氨酸,cysteine,半胱氨酸,L-(+)-Cysteine |
Endogenous Metabolite | Metabolism |
L-Cysteine (L-(+)-Cysteine) 是人体非必需的含硫氨基酸。L-Cysteine 对蛋白质合成、解毒和多种代谢功能很重要。L-Cysteine 存在于指甲、皮肤和头发的主要蛋白质-角蛋白中,对胶原蛋白的生成、皮肤弹性和质地都很重要。L-Cysteine 是抗氧化剂谷胱甘肽的一种成分,在辅酶A、肝素和生物素等基本生化物质的代谢中起着重要作用,也是氨基酸牛磺酸的制造所必需的。 | |||
T1085L |
Glutathione oxidized
Bi(glutathion-S-yl),Oxidized glutathione,L-谷胱甘肽(氧化型),氧化型谷胱甘肽,L-Glutathione oxidized,Glutathione disulfide,L(-)-Glutathione,GSSG |
Reactive Oxygen Species; Endogenous Metabolite; Glutathione reductase | Immunology/Inflammation; Metabolism; NF-κB; oxidation-reduction |
Glutathione oxidized (L(-)-Glutathione) 是氧化型谷胱甘肽,谷胱甘肽是细胞内一种主要的抗氧化剂和解毒剂。 | |||
TN5283 |
L-Cysteine hydrochloride hydrate
L-Cysteine hydrochloride monohydrate,L-半胱氨酸盐酸盐一水物,L-半胱氨酸盐酸盐 一水合物 |
Others; Endogenous Metabolite | Metabolism; Others |
L-Cysteine hydrochloride hydrate (L-Cysteine hydrochloride monohydrate) 是条件必需氨基酸,是硫化氢、谷胱甘肽和牛磺酸等生物活性分子的前体。它可以抑制胃饥饿素,抑制啮齿动物和人类的食欲。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00979 |
GSH-S Protein, Human, Recombinant (His)
Glutathione Synthetase,GSS,GSH-S,GSH Synthetase,G |
Human | E. coli |
Glutathione Synthetase belongs to the eukaryotic GSH synthase family. Glutathione Synthetase is the second enzyme in the glutathione biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine and glycine to form glutathione. Glutathione play an important role in a variety of biological functions, including detoxification of xenobiotics, protection of cells from oxidative damage by free radicals, and membrane transport. The protein functions as a homodimer to catalyze the secon... | |||
TMPJ-01142 |
CDO1 Protein, Human, Recombinant (His)
CDO-I,CDO,Cysteine Dioxygenase Type I,CDO1,Cyst... |
Human | E. coli |
Cysteine Dioxygenase Type 1 (CDO1) is a mammalian non-heme iron enzyme that belongs to the cysteine dioxygenase family. CDO1 is highly expressed in the liver and placenta, and has a low expression in heart, brain and pancreas. CDO1 can also be detected in hepatoblastoma HepG2 cells. CDO1 catalyzes the conversion of L-cysteine to cysteine sulfinic acid by incorporation of dioxygen. CDO1 is a vital regulator of cellular cysteine concentrations and has an essential role in maintaining the hepatic c... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TMIJ-0384 |
L-Cysteine-d3
|
||
L-Cysteine-d3 是 L-Cysteine 的氘代化合物。L-Cysteine 的 CAS 号为 52-90-4。L-Cysteine 是人体非必需的含硫氨基酸。L-Cysteine 对蛋白质合成、解毒和多种代谢功能很重要。L-Cysteine 存在于指甲、皮肤和头发的主要蛋白质-角蛋白中,对胶原蛋白的生成、皮肤弹性和质地都很重要。L-Cysteine 是抗氧化剂谷胱甘肽的一种成分,在辅酶A、肝素和生物素等基本生化物质的代谢中起着重要作用,也是氨基酸牛磺酸的制造所必需的。 |