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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T19922 |
L-m-Tyrosine
L(-)mTyrosine,3-羟基-L-苯基丙氨酸,L (-) m Tyrosine,LmTyrosine,3-Hydroxy-L-Phenylalanine,L-(-)-m-Tyrosine |
Others | Others |
L-m-Tyrosine (3-Hydroxy-L-Phenylalanine) 是一种非天然氨基酸。L-m-Tyrosine 在治疗帕金森病、关节炎和阿尔茨海默病方面显示出潜力。 | |||
T40408 |
N-Pivaloyl-L-tyrosine
|
Others | Others |
N-Pivaloyl-L-tyrosine is an N-pivaloyl amino acid ester. | |||
T40846 |
3,5-Difluoro-L-tyrosine
|
Others | Others |
3,5-Difluoro-L-tyrosine is a functional and tyrosinase-resistant mimic of tyrosine, commonly utilized for evaluating the substrate specificity of protein tyrosine phosphatases (PTPs). | |||
T20698 |
Leucyltyrosine
L-Leucyl-L-tyrosine |
Others | Others |
Leucyltyrosine is a dipeptide. | |||
T67308 |
3-Fluoro-L-tyrosine
|
Others | Others |
3-Fluoro-L-tyrosine 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T67308。 | |||
T126438 |
L-Tyrosine, methyl ester
|
Others | Others |
L-Tyrosine, methyl ester 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T126438,CAS号为 1080-06-4。 | |||
T31162 |
Cysteinyltyrosine
N-L-Cysteinyl-L-tyrosine,Cys-tyr |
Others | Others |
Cysteinyltyrosine is a dipeptide composed of cysteine and tyrosine. It is an incomplete breakdown product of protein digestion or protein catabolism. | |||
T20554 |
N-Benzoyltyrosine
N-Benzoyl-L-tyrosine |
Others | Others |
N-benzoyl tyrosine is a dipeptide. | |||
T65730 |
N-Fmoc-3-nitro-L-tyrosine
|
Others | Others |
N-Fmoc-3-nitro-L-tyrosine 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65730,CAS号为 136590-09-5。 | |||
T32675 |
Leucyl-leucyl-tyrosine
L-Leu-L-leu-L-tyr |
Others | Others |
Leucyl-leucyl-tyrosine is a bioactive chemical. | |||
T124433 |
3-Nitro-L-tyrosine ethyl ester hydrochloride
|
Others | Others |
3-Nitro-L-tyrosine ethyl ester hydrochloride 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124433。 | |||
T65630 |
N-Benzoyl-L-tyrosine ethyl ester
|
||
N-Benzoyl-L-tyrosine ethyl ester 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65630,CAS号为 3483-82-7。 | |||
T77237 |
N,O-Didansyl-L-tyrosine cyclohexylammonium
|
||
N,O-Didansyl-L-tyrosine cyclohexylammonium 是一种有效的选择性胸苷酸合成酶 (TS) 抑制剂,作用于Escherichia coli,Lactobacillus casei 和人的 TS 的IC50值分别是 5.0,3.4 和 119 μM。 | |||
T40840 |
H-Tyr-Ala-OH
H-Tyr-Ala-OH,Tyrosylalanine |
Others | Others |
H-Tyr-Ala-OH (Tyrosylalanine) 是一种L-酪氨酸和L-丙氨酸组成的二肽。 | |||
T5467 |
SAR125844
SAR125884 |
Apoptosis; c-Met/HGFR | Apoptosis; Tyrosine Kinase/Adaptors |
SAR125844 是高度选择性可逆ATP 竞争性的MET 受体酪氨酸激酶抑制剂,其IC50值为4.2 nM。能抑制细胞中MET 的自磷酸化。 | |||
T41274 |
p-Fluoro-L-phenylalanine
|
Hydroxylase | Metabolism |
p-Fluoro-L-phenylalanine 是酪氨酸羟化酶的一种底物。它可以与大肠杆菌的 L-亮氨酸特异性受体结合,KD 为0.26 μM。 | |||
T11727 |
JPH203 dihydrochloride
KYT-0353 dihydrochloride |
Others | Others |
JPH203 dihydrochloride (KYT-0353 dihydrochloride) 是一种酪氨酸类似物,可作为 L 型氨基酸转运蛋白 1 (LAT1) 的选择性抑制剂,用于癌症研究。 | |||
T5473 |
ASP5878
ASP-5878 |
FGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
ASP5878 是一种 FGFR 1 (IC50:0.47 nM)、FGFR 2 (IC50:0.6 nM)、FGFR 3 (IC50:0.74 nM)、和 FGFR 4 (IC50:3.5 nM)的抑制剂,具有口服活性,具有潜在的抗肿瘤作用。 | |||
T3691 |
(Rac)-SAR131675
SAR131675 |
VEGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
(Rac)-SAR131675 是一种有效的、选择性的VEGFR3抑制剂,其IC50=23 nM。 | |||
T2500 |
Cediranib
AZD2171,NSC-732208,西地尼布 |
VEGFR; FLT; PDGFR; c-Kit; Autophagy | Angiogenesis; Autophagy; Tyrosine Kinase/Adaptors |
Cediranib (AZD2171) 是一种可口服的高选择性VEGFR2抑制剂,对Flt1、KDR、Flt4、PDGFRα、PDGFRβ和c-Kit 的IC50值分别为小于1、小于3、5、5、36和 2nM。 | |||
T27513 |
GW7845
GW 7845,GW-7845 |
Others | Others |
GW7845, an L-tyrosine derivative, is a PPAR-γ agonist. | |||
T31410 |
D-Fluoromethyltyrosine F-18
BAY 86 9596,BAY 869596,BAY 86-9596,J2.566.882K,BAY-86-9596 F-18 |
Others | Others |
Fluoroethyl-l-tyrosine (18F) or 18F-FET is a neuro-oncology PET tracer. | |||
T24039 |
Erbstatin
|
Others | Others |
Erbstatin is a tyrosine-protein kinase inhibitor. When combined with foroxymithine, it has antineoplastic activity against L-1210 leukemia. | |||
T41208 |
NB-caged Tyrosine hydrochloride
ONBY,NB-caged Tyrosine hydrochloride |
Others | Others |
NB-caged Tyrosine hydrochloride is a L-Tyrosine caged with photosensitiveortho-nitrobenzyl side chain. Rapidly releases tyrosine when photolyzed (300-350 nm excitation). Is readily incorporated intoE.coliproteins via inclusion in growth media. | |||
T19890 |
Tyrosyl-glycyl-glycine
|
Others | Others |
Tyrosyl-glycyl-glycine 是一种由脑啡肽酶释放的三肽,是一种代谢产物,由一个L-酪氨酸和两个甘氨酸残基按顺序连接而成。 | |||
T84705 |
Tyrosinase-IN-22
5-Chloro-2-mercaptobenzimidazole |
Others | Others |
Tyrosinase-IN-22(compound 4)是L-酪氨酸和L-多巴的抑制剂,IC50值分别为60 nM和30 nM。具备显著的抗氧化及抗黑素生成特性,适合相关领域研究。 | |||
T74045 |
H-Lys-Tyr-OH TFA
|
Others | Others |
H-Lys-Tyr-OH TFA (Lysyltyrosine TFA)为L-赖氨酸与L-酪氨酸构成的二肽。该化合物通过促进去甲肾上腺素与酪氨酸在大脑中的释放,用于预防神经系统疾病或提升大脑功能。 | |||
T71576 |
SIM010603
|
Others | Others |
SIM010603 is a structurally novel, oral, multi-targeted receptor tyrosine kinase inhibitor. SIM010603 inhibited stem cell factor receptor (Kit), vascular endothelial growth factor receptor-2 (VEGFR-2), platelet-derived growth factor receptor-β (PDGFR-β), glial cell line-derived neurotrophic factor receptor (Rearranged during Transfection; RET), and Fms-like tyrosine kinase-3 (FLT3) with IC(50) values between 5.0 and 68.1 nmol/l. SIM010603 inhibited the phosphorylation of PDGFR-β and VEGFR-2. Mor... | |||
T71082 |
DW532
|
Others | Others |
DW532 is one of simplified analogues of hematoxylin that has shown broad-spectrum inhibition on tyrosine kinases and in vitro anti-cancer activities. DW532 inhibited EGFR and VEGFR2 in vitro kinase activity (the IC50 values were 4.9 and 5.5 μmol/L, respectively), and suppressed their downstream signaling. DW532 dose-dependently inhibited tubulin polymerization via direct binding to tubulin, thus disrupting the mitotic spindle assembly and leading to abnormal cell division. In a panel of human ca... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0493 |
L-Tyrosine
Tyrosine,P-Tyrosine,L-酪氨酸,L-p-Tyrosine,(S)-Tyrosine,酪氨酸 |
Amino Acids and Derivatives; Endogenous Metabolite | Metabolism |
L-Tyrosine ((S)-Tyrosine) 是一种非必需氨基酸,对后部皮层中柠檬酸合成酶具有抑制活性。 | |||
TN6749 |
3,5-Diiodo-L-tyrosine dihydrate
|
Others | Others |
3,5-Diiodo-L-tyrosine dihydrate 是一种天然产物。 | |||
T4890 |
3-Nitro-L-tyrosine
3-Nitrotyrosine,3-硝基-L-酪氨酸 |
Endogenous Metabolite | Metabolism |
3-Nitro-L-tyrosine (3-Nitrotyrosine) 在系统自免疫原性条件下,能够作无氮自由基修饰蛋白的生物标记物。 | |||
T5280 |
3-Chloro-L-Tyrosine
3-氯-L-酪氨酸,3-Chlorotyrosine,Chlorotyrosine |
Others; Endogenous Metabolite | Metabolism; Others |
3-Chloro-L-Tyrosine (Chlorotyrosine) 是一种髓过氧化物酶催化氧化的特异性标志物,在从人动脉粥样硬化内膜分离的低密度脂蛋白中显著升高。 | |||
T5292 |
N-Acetyl-L-tyrosine
N-乙酰-L-酪氨酸,N-Acetyltyrosine,Ac-Tyr-OH |
Others; Endogenous Metabolite | Metabolism; Others |
N-Acetyl-L-tyrosine (Ac-Tyr-OH) 是一种来源于AA 乙酰酶作用下的酪氨酸,和芳香族氨基酸脱羧酶缺乏症以及酪氨酸血症有关,能够作为儿茶酚胺的前体,用于治疗神经递质。 | |||
T5568 |
H-Tyr(3-I)-OH
3-碘-L-酪氨酸,3-Iodo-L-tyrosine |
Endogenous Metabolite | Metabolism |
H-Tyr(3-I)-OH (3-Iodo-L-tyrosine) 是酪氨酸羟化酶抑制剂和甲状腺激素 的中间体。 | |||
T1653 |
Liothyronine
Tresitope,O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine,碘噻罗宁,Triiodothyronine,三碘甲状腺原氨酸,L-3,3',5-Triiodothyronine,3,3',5-Triiodo-L-thyronine,Lyothyronine |
Thyroid hormone receptor(THR); Endogenous Metabolite | Endocrinology/Hormones; Metabolism |
Liothyronine (Tresitope) 是一种人工合成的甲状腺激素,能够激活 β1 甲状腺激素受体 (TRβ1)。Liothyronine 能促进糖、蛋白质和脂肪三大物质的代谢,加速组织细胞的氧化过程,维持正常的基础代谢率,有利于机体的生长发育。 | |||
T20555 |
Glycyltyrosine
NSC 118362,Gly Tyr,NSC-118362,Gly-Tyr,NSC118362,N-Glycyl-L-tyrosine |
Others | Others |
Glycyltyrosine, a dipeptide composed of tyrosine and glycine, is an incomplete breakdown product of protein catabolism or protein digestion. | |||
T3377 |
L-Phenylalanine
L-苯丙氨酸,(S)-2-Amino-3-phenylpropionic acid,phenylalanine,3-Phenyl-L-alanine |
Calcium Channel; Endogenous Metabolite; iGluR | Membrane transporter/Ion channel; Metabolism; Neuroscience |
L-Phenylalanine (3-Phenyl-L-alanine) 是分离自大肠杆菌的必需氨基酸,是 NMDARs(KB573 μM) 和非 NMDARs 的甘氨酸和谷氨酸结合位点的竞争性拮抗剂,用于食品香料和药品的生产中。它是一种电压依赖性 α2δ 亚基 Ca2+通道拮抗剂,Ki 为 980 nM。 | |||
T3737 |
3-(2,4-Dihydroxyphenyl)propanoic acid
3-(2,4-二羟基苯)丙酸,Hydroumbellic acid,2,4-Dihydroxyhydrocinnamic acid |
Tyrosinase | Proteases/Proteasome |
3-(2,4-Dihydroxyphenyl)propanoic acid (Hydroumbellic acid) 是竞争性酪氨酸酶 (tyrosinase) 抑制剂,可抑制 L-Tyrosine 和 DL-DOPA,IC50和 Ki 分别为 3.02 μM 和 11.5 μM。 | |||
T4781 |
N-Acetyl-L-phenylalanine
N-Ac-Phenylalanine,N-乙酰-L-苯丙氨酸 |
Others; Endogenous Metabolite | Metabolism; Others |
N-Acetyl-L-phenylalanine (N-Ac-Phenylalanine) 是一种大肠杆菌中的主要酰基氨基酸,由 L-苯丙氨酸和乙酰辅酶 A 合成。 | |||
T5290 |
(S)-2-Hydroxy-3-phenylpropanoic acid
L-(−)-3-Phenyllactic acid,L-3-苯乳酸 |
Others; Endogenous Metabolite | Metabolism; Others |
(S)-2-Hydroxy-3-phenylpropanoic acid (L-(−)-3-Phenyllactic acid) 是苯丙氨酸的代谢产物。苯丙酮尿症患者体液中苯丙氨酸的水平升高。 | |||
T75563 |
Vanicoside E
|
Others | Others |
Vanicoside E 是一种抗氧化和抗癌剂。Vanicoside E 抑制L-Tyrosine 和L-DOPA,IC50为 45.23 μM 和 189.96 μM。 | |||
TN2288 |
Uralenol
乌拉尔醇 |
Others; Estrogen/progestogen Receptor; Tyrosinase | Endocrinology/Hormones; Others; Proteases/Proteasome |
Uralenol significantly shows the inhibitory activities against the PTP1B enzyme; it also shows inhibitory activities on mushroom tyrosinase using l-tyrosine as substrate( IC50 =49.5 μM). Uralenol shows potent anti-proliferation effects on ER-positive breast cancer MCF-7 cells in vitro. | |||
TN3607 |
Catalpalactone
|
cAMP | GPCR/G Protein |
Catalpalactone exhibits high antitermitic, and cytotoxic activities, it exhibits potent inhibitory effects on lipopolysaccharide-induced NO synthesis in RAW 264.7 cells , with IC50 values of 9.80 microM. Catalpalactone can inhibit dopamine biosynthesis by |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-05308 |
CD45 Protein, Human, Recombinant (aa 1-529, His)
GP180,B220,L-CA,protein tyrosine phosphata... |
Human | HEK293 Cells |
CD45 Protein, Human, Recombinant (aa 1-529, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.4 kDa and the accession number is P08575-5. | |||
TMPY-05748 |
CD45 Protein, Human, Recombinant (aa 26-577, His)
L-CA,T200,LCA,B220,protein tyrosine |
Human | HEK293 Cells |
CD45 Protein, Human, Recombinant (aa 26-577, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62.2 kDa and the accession number is P08575-3. | |||
TMPJ-00808 |
CD45RA Protein, Human, Recombinant (His)
PTPRC,CD45R,CD45,LCA,protein tyrosine phos... |
Human | HEK293 Cells |
CD45RA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 100-135 KDa and the accession number is P08575-8. | |||
TMPJ-00794 |
CD45 Protein, Mouse, Recombinant (His)
CD45,receptor-type tyrosine-protein phosphatase C,C... |
Mouse | HEK293 Cells |
CD45 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 120-160 KDa and the accession number is P06800. | |||
TMPJ-00410 |
CD45R0 Protein, Human, Recombinant (His)
CD45 antigen,L-CA,protein tyrosine phospha... |
Human | HEK293 Cells |
CD45R0 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 80-120 KDa and the accession number is P08575-4. | |||
TMPY-04277 |
CD45 Protein, Mouse, Recombinant (hFc)
Cd45,protein tyrosine phosphatase, receptor type, C... |
Mouse | HEK293 Cells |
CD45 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.7 kDa and the accession number is P06800-6. | |||
TMPY-03270 |
CD45 Protein, Mouse, Recombinant (aa 453-1152, His & GST)
Ly-5,CD45R,Lyt-4,T200,loc,protein... |
Mouse | Baculovirus Insect Cells |
CD45 Protein, Mouse, Recombinant (aa 453-1152, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 108.2 kDa and the accession number is AAA39458.1. | |||
TMPY-03468 |
CD45 Protein, Mouse, Recombinant (aa 453-1152)
loc,Lyt-4,protein tyrosine phosph... |
Mouse | Baculovirus Insect Cells |
CD45 Protein, Mouse, Recombinant (aa 453-1152) is expressed in Baculovirus insect cells. The predicted molecular weight is 81 kDa and the accession number is AAA39458.1. | |||
TMPY-00711 |
CD45 Protein, Human, Recombinant (hFc)
GP180,L-CA,LY5,T200,protein tyrosine |
Human | HEK293 Cells |
CD45 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.1 kDa and the accession number is P08575-4. | |||
TMPJ-00230 |
EFNB1 Protein, Mouse, Recombinant (hFc & His)
EFNB1,LERK-2,EPH-related receptor tyro... |
Mouse | HEK293 Cells |
Mouse Ephrin-B1 is a single-pass type I membrane protein which belongs to the ephrin family. It contains an ephrin RBD (ephrin receptor-binding) domain, and expressed in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas. Ephrin-B1 is cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. It binds promiscuously Eph receptors residing on... | |||
TMPJ-00114 |
EFNA3 Protein, Mouse, Recombinant (hFc)
EFL2,LERK-3,EFNA3,Ephrin-A3,EHK1-L |
Mouse | HEK293 Cells |
Ephrins-A3 belongs the Ephrins ligand family which involved in a variety of biological processes, especially in the nervous system and in erythropoiesis. It is shown that Ephrin-A3 is expressed in brain, skeletal muscle, spleen, thymus, prostate, testis, ovary, small intestine, and peripheral blood leukocytes. Ephrin-A3 has a GPI anchor following the extracellular sequence and a signal sequence of 22 amino acids. Ephrin-A3 can bind EphA2, EphA3, EphA4, EphA5, EphA6, EphA7, EphA8 and EphB1. Futhe... | |||
TMPJ-00938 |
4HPPD Protein, Human, Recombinant (His)
PPD,4HPPD,HPD,4-Hydroxyphenylpyruvate Dioxygenase,H... |
Human | E. coli |
4-Hydroxyphenylpyruvate Dioxygenase (4HPPD) belongs to the 4HPPD family. 4HPPD is a key enzyme in the degradation of tyrosine, which catalyzes the second reaction in the catabolism of tyrosine the conversation of 4-hydroxyphenylpyruvate to homogentisate. 4HPPD exists in homodimer forms, which uses zinc as a cofactor to catalyze the third step in the conversion of L-phenylalanine to fumarate and acetoacetic acid. When the active 4HPPD enzyme concentration is low in the human body, it results in h... | |||
TMPJ-00290 |
GFR Alpha-2/GFRA2 Protein, Human, Recombinant (hFc & His)
TRNR2,GDNFR-beta,TGF-β-related neurotrophic factor ... |
Human | HEK293 Cells |
GDNF family receptor alpha-2 is a glycosylphosphatidylinosito l (GPI)-linked cell surface receptor. It is part of the GDNF receptor family. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. GFRA2 mediates the NRTN-induced autophosphorylation and activation of the RET receptor. It also able to mediate GDNF signaling through the RET tyrosine kina... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T36384 |
DL-Tyrosine-13C9,15N
L-Tyrosine-13C9,15N |
||
L-Tyrosine-13C9,15N is intended for use as an internal standard for the quantification of L-tyrosine by GC- or LC-MS. L-Tyrosine is a non-essential amino acid.1It is produced by hydroxylation of phenylalanine by phenylalanine hydroxylase but can also be obtained from dietary sources or degradation of endogenous proteins, resulting in L-tyrosine release.1,2L-Tyrosine is a precursor in the biosynthesis of catecholamine neurotransmitters, melanins, and thyroid hormones.3Plasma, skeletal muscle, and... | |||
TMID-0114 |
3-Methoxy-L-tyrosine-d3 monohydrate
|
||
3-Methoxy-L-tyrosine-d3 monohydrate 是 3-Methoxy-L-tyrosine monohydrate 的氘代化合物。3-Methoxy-L-tyrosine monohydrate 的 CAS 号为 200630-46-2。 |