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Search Results for " l moses "

Targets Recommended: Others

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Cat. No.	Product Name	Target	Signaling Pathways
T36109	L Moses dihydrochloride	Others	Others
	High affinity and selective cell-permeable p300/CBP-associated factor (PCAF) inhibitor (Ki = 47 nM). Exhibits no significant activity against a panel of 48 other bromodomains except GCN5 (Kd = 600 nM). Exhibits >4500-fold selectivity for PCAF over BRD4. Also exhibits metabolic stability in mouse and human liver microsomes and no observable cytotoxicity in peripheral blood mononuclear cells (PBMC). Moustakim et al (2017) Discovery of a PCAF bromodomain chemical probe. Angew.Chem.Int.Ed. 56 827 P...
T11796L	L-Moses L-45	Others	Others
	L-45 is the first potent and cell-active bromodomain (Brd) inhibitor of p300/CBP-associated factor (PCAF) (Kd: 126±15 nM).
T62424	L-Moses dihydrochloride	Others	Others
	L-Moses (L-45) dihydrochloride 是一个有效的、选择性 p300/CBP 相关因子 (PCAF) 溴结构域 (Brd) 抑制剂 (Kd: 126 nM)。
T35831	Deoxy Donepezil (hydrochloride)	Others	Others
	Deoxy donepezil is a potential impurity found in bulk preparations of the acetylcholinesterase inhibitor donepezil .1It is produced as a by-product during donepezil synthesis.2 1.Krishna Reddy, K.V.S.R., Moses Babu, J., Anil Kumar, P., et al.Identification and characterization of potential impurities of donepezilJ. Pharm. Biomed. Anal.35(5)1047-1058(2004) 2.Krizmanic, I., Lerman, L., Samardzic, Z., et al.Impurities of donepezil(2009)
T37605	D-DOPA	Others	Others
	D-DOPA is an enantiomer of the dopamine precursor L-DOPA . It can be converted to L-DOPAviasequential oxidation and transamination, which are mediated by D-amino acid oxidase (DAAO) and DOPA transaminase, respectively, in rat kidney homogenates.1It reduces the number of dopaminergic neurons in primary rat embryonic mesencephalic cultures in a concentration-dependent manner.2Intraventricular administration of D-DOPA (200 μg/animal) increases striatal dopamine levels in rats.3D-DOPA (20 mg/kg, i.p...

化合物

L Moses dihydrochloride

Cat.No: T36109

Target: Others

Cat.No: T11796L

Synonym: L-45

Target: Others

L-Moses dihydrochloride

Cat.No: T62424

Target: Others

Deoxy Donepezil (hydrochloride)

Cat.No: T35831

Target: Others

Cat.No: T37605

Target: Others

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