110
52
23
5
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T2683 |
IWP L6
Porcn Inhibitor III,IWP-L6,Porcn Inhibitor III |
Porcupine | Stem Cells |
IWP L6 (Porcn Inhibitor III) 是一种高活性的 Porcn 抑制剂(EC50:0.5 nM)。 | |||
T0752 |
Ascorbyl palmitate
L-抗坏血酸棕榈酸酯,L-Ascorbic acid 6-hexadecanoate,6-O-Palmitoyl-L-ascorbic acid,L-Ascorbyl 6-palmitate,抗坏血酸棕榈酸酯 |
Reactive Oxygen Species; Endogenous Metabolite | Immunology/Inflammation; Metabolism; NF-κB |
Ascorbyl palmitate (L-Ascorbic acid 6-hexadecanoate) 是由抗坏血酸和棕榈酸形成的一种酯,一种脂溶性形式的维生素 C。 | |||
T36320 |
C6 L-threo Ceramide (d18:1/6:0)
C6 L-threo Ceramide (d18:1/6:0) |
Others | Others |
C6 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides., C6 L-threo Ceramide is cytotoxic to U937 cells in vitro (IC50 = 18 μM). It is metabolically inactive and, unlike C6 L-erythro ceramide , C6 L-threo ceramide cannot be converted to C6 glucosylceramide by ceramide glucosyltransferase. C6 L-threo Ceramide enhances IL-4 production induced by phorbol 12-myristate 13-acetate in EL4 T cells when used at a concentration of 10 μM. | |||
T36319 |
C6 L-erythro Ceramide (d18:1/6:0)
C6 L-erythro Ceramide (d18:1/6:0) |
Others | Others |
C6 L-erythro Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. It is metabolized by ceramide glucosyltransferase to form C6 L-erythro glucosylceramide. C6 L-erythro Ceramide is cytotoxic to U937 cells (IC50 = 18 μM). | |||
T21355 |
6-Chloro-1-tetralone
6-Chloro-α-Tetralone,5-CHLORO-L-INDOMONE,6-chloro-3;5-CHLORO-1-INDOMONE,5-CHLORO-1-INDOMONE,6-chloro-3 |
Others | Others |
6-Chloro-1-tetralone (6-chloro-3;5-Chloro-1-Indomone) 是合成药物化合物的重要中间体。 | |||
T6353 |
(-)-p-Bromotetramisole Oxalate
(-)-对溴四咪唑草酸盐,L-p-Bromotetramisole oxalate,6-Bromolevamisole oxalate,(-)-p-Bromolevamisole oxalate |
Phosphatase; Phosphorylase | Metabolism |
(-)-p-Bromotetramisole Oxalate (6-Bromolevamisole oxalate) 是一种强效的、非特异性碱性磷酸酶抑制剂。 | |||
T1351 |
H-Lys(Tfa)-OH
|
Amino Acids and Derivatives | Metabolism |
H-Lys(Tfa)-OH 是L-lysine cyclodeaminase 的抑制剂。 | |||
T9463 |
6-HYDROXYLAMINOURACIL
|
Others | Others |
6-HYDROXYLAMINOURACIL 是尿嘧啶的衍生物,它可以诱导肿瘤细胞的 DNA 损伤和凋亡,在体外抑制肿瘤细胞的生长。 | |||
T40423 |
L48H37
|
Others | Others |
L48H37是Curcumin的一个化学稳定类似物。它对髓系分化蛋白2 (MD2) 表现出强效的抑制性质,作为一个特异性抑制剂。其机制包括抑制LPS-TLR4/MD2的相互作用和信号传导。L48H37主要用于脓血症和肺损伤研究[1]。 | |||
T9398 |
NSC 73150
NSC 97967 |
Others | Others |
6-methyl-2-[2-[(E)-(6-oxo-1-cyclohexa-2,4-dienylidene)methyl]hydraziny l]-1H-pyrimidin-4-one (NSC 73150) 是一种嘧啶衍生物,具有抗肿瘤活性,临床前研究表明,它可以抑制各种肿瘤细胞系的生长,包括乳腺癌、肺癌和肝癌,也被发现可诱导细胞凋亡、抑制血管生成和抑制肿瘤转移。 | |||
T20396 |
Levadopa Related Compound A
6-Hydroxydopa, L-,L-Hydroxydopa |
Others | Others |
Levadopa Related Compound A is the 6-hydroxy derivative of the amino acid L-DOPA with neurotoxic properties. Exogenously administered 6-Hydroxy-L-DOPA is biotransformed by an amino acid decarboxylase to the highly potent and catecholamine-selective neurot | |||
T32453 |
L 650719
6-HTS,L650719,L-650719 |
Others | Others |
L 650719 is a bioactive chemical. | |||
T25715 |
LHRH, Ala(6)-
L 1868,L-1868,L1868 |
Others | Others |
LHRH, Ala(6)- is a synthetic luteinizing hormone-releasing hormone agonist agent. | |||
T22910 |
L-AP6
|
Others | Others |
selective agonist for 'quis'-sensitized site | |||
T31823 |
Fluorodopa F 18
Fluorodopa (18F),6-(18F)Fluoro-L-DOPA,F-DOPA,L-6-(18F)Fluoro-DOPA,6-(18F)Fluorodopamine |
Others | Others |
Fluorodopa F 18 can be used as radioactive agent. | |||
T26516 |
ABH Hydrochloride
6-borono-L-norleucine,ABH HCl |
Others | Others |
ABH Hydrochloride is an arginase inhibitor, it enhances both male and female sexual arousal responses. | |||
T31635 |
Enkephalin-met, lys(6)-
Met-enk-L,6-Lys-met-enkephalin |
Others | Others |
Enkephalin-met, lys(6)- is an opioid hexapeptide found in adrenal medulla. | |||
T30154 |
Ascorbyl myristate
Ascorbyl monomyristate,6-tetradecanoate,L-Ascorbic acid |
Others | Others |
Ascorbyl myristate is a bioactive chemical. | |||
T32511L |
L-796,778 acetate
L-796,778 acetate(217480-25-6 Free base) |
Somatostatin | GPCR/G Protein |
L-796,778 acetate 是一种选择性生长抑素受体激动剂,对 sst3的IC50为24nM,对sst1、sst2、sst4和sst5的IC50大于1000nM。 | |||
T5149 |
MC-Val-Cit-PAB
N-[6-(2,5-二氢-2,5-二氧代-1H-吡咯-1-基)-1-氧代己基]-L-缬氨酰-N5-(氨基甲酰基)-N-[4-(羟甲基)苯基]-L-鸟氨酰胺 |
Others; AChR; ADC Linker | Antibody-drug Conjugate/ADC Related; Neuroscience; Others |
MC-Val-Cit-PAB 是一种组织蛋白酶可裂解的 ADC 接头,用于制备抗体-药物偶联物。 | |||
T32451 |
L 644257
L-644257,6-Coham,Nmanchol,L644257 |
Others | Others |
L 644257 is a synthetic glycolipid for study liposomes in vivo. | |||
T80526 |
L-K6L9
|
||
L-K6L9 对于囊性纤维化患者的铜绿假单胞菌 (P. aeruginosa) 表现出显著的抗菌 (antimicrobial) 活性和抗生物膜 (anti-biofilm) 能力。该化合物的抗酶解性质保证了其在体内的稳定性,且不引发细菌的耐药性。 | |||
T83853 |
L-K6L9 TFA
|
||
L-K6L9 是由 L-亮氨酸和 L-赖氨酸的L-异构体组成的溶细胞肽。对LNCaP-CL1 雄激素独立型和22Rv1以及LNCaP雄激素依赖型人类前列腺癌细胞具有细胞毒性(LC50分别为4、4和6 µM),同时也对非癌性NIH3T3小鼠成纤维细胞和OL人类包皮成纤维细胞具有细胞毒性(LC50分别为7和5 µM)。在100 µM的浓度下,引起分离的人类红细胞溶血。 | |||
T33562 |
N6-(Retinylidene)lysine
Nepsilon-All-trans-retinylidene-L-lysine |
Others | Others |
N6-(Retinylidene)lysine is a protein. | |||
T32818 |
L-Lysine, N6,N6'-(1,8-dioxo-1,8-octanediyl)bis-
|
Others | Others |
L-Lysine, N6,N6'-(1,8-dioxo-1,8-octanediyl)bis- is a bioactive chemical. | |||
T124053 |
Vinylphenol, O-[L-Rhamnopyranosyl-(1-6)-?-D-glucop
|
Others | Others |
Vinylphenol, O-[L-Rhamnopyranosyl-(1-6)-?-D-glucop 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T124053,CAS号为 86849-78-7。 | |||
T69626 |
L6H21
|
Others | Others |
L6H21 is an inhibitor of the interaction and signaling transduction of LPS-TLR4/MD-2 (myeloid differentiation 2). | |||
T70932 |
L6H9
|
Others | Others |
L6H9 is a novel inhibitor of myeloid differentiation factor 2 (MD2), suppressing HG-induced expression of ACE and AT1 receptor and Angiotensin II (AngII) production in renal NRK‐52E cells, resulting in the decrease in fibrosis markers such as TGF-β and collagen IV. | |||
T83708 |
Mca-KPLGL-Dap(Dnp)-AR-NH2 TFA
Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 (Dpa = N-3-(2,4-dinitrophenyl)l-α,β-diaminopropionyl),FS-6 |
||
Mca-KPLGL-Dap(Dnp)-AR-NH2是一种用于矩阵金属蛋白酶(MMPs)的荧光底物。当被MMPs切割时,7-甲氧基香豆素-4-乙酰基(Mca)会释放,其荧光可用来定量MMP活性。Mca的激发/发射峰值分别为328/420 nm。 | |||
T67613 |
N6-Trifluoroacetyl-L-Lysine
|
Others | Others |
N6-Trifluoroacetyl-L-Lysine 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T67613,CAS号为 116169-90-5。 | |||
T80527 |
D-K6L9
|
||
D-K6L9表现出针对囊性纤维化患者中的P. aeruginosa具有抗菌(antimicrobial)及抗生物膜效应,能稳定抵抗囊性纤维化痰中的蛋白酶降解,且不诱发细菌耐药性。 | |||
T64488 |
6-[(3R,4R)-3-(Acetyloxy)-N,4-dimethyl-6-oxo-L-norleucine]cyclosporin A
|
Others | Others |
6-[(3R,4R)-3-(Acetyloxy)-N,4-dimethyl-6-oxo-L-norleucine]cyclosporin A 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64488。 | |||
T73264 |
L2H2-6OTD
|
Others | Others |
L2H2-6OTD, 为含有一至四个G-四联体结合环的端粒抑制素类似物,显示出对端粒酶 (telomerase) 的抑制活性,其IC50值达到15 nM。 | |||
T61968 |
PD-1/PD-L1-IN 6
|
Others | Others |
PD-1/PD-L1-IN 6 (compound A13) 是有效的PD-1/PD-L1相互作用抑制剂(IC50为 132.8 nM)。PD-1/PD-L1-IN 6 显示出显著的免疫调节活性。 在 Hep3B/OS-8/hPD-L1 与 CD3 T 细胞共培养模型中,PD-1/PD-L1-IN 6显著提高干扰素 -γ 分泌,且无明显毒性作用。 在 T 细胞-肿瘤共培养模型中,PD-1/PD-L1-IN 6恢复免疫应答。 | |||
T124311 |
Apigenin 6,8-di-C-alpha-L-arabinopyranoside
|
Others | Others |
Apigenin 6,8-di-C-alpha-L-arabinopyranoside 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T124311,CAS号为 73140-47-3。 | |||
T77670 |
(1R,5S,6r)-N-(2-methyl-1-((3-methylpyridin-2-yl)oxy)propan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide L(+)-Tartaric acid
|
Somatostatin | GPCR/G Protein |
(1R,5S,6r)-N-(2-methyl-1-((3-methylpyridin-2-yl)oxy)propan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide L(+)-Tartaric acid 是一种潜在的SSTR4激动剂。 | |||
T79557 |
fac-[Re(CO)3(L6)(H2O)][NO3]
|
Apoptosis | Apoptosis |
fac-[Re(CO)3(L6)(H2O)][NO3](compound 6)是一种具有针对线粒体功能失调的抗癌活性的铼(I)三羰基水配合物。该化合物对前列腺癌细胞展现出显著的细胞毒性,具有50 nM的IC50值(PC-3细胞)。fac-[Re(CO)3(L6)(H2O)][NO3]能够主要集中在细胞核,抑制PC3细胞的ATP生成并诱导细胞凋亡,而不触发坏死、焦亡或自噬过程。 | |||
TNU1629 |
1-[3’-O-[(4,4’-dimethoxytriphenyl)methyl]-a-L-threofuranosyl]-N6-benzoyladenine
|
Others | Others |
1-[3’-O-[(4,4’-dimethoxytriphenyl)methyl]-a-L-threofuranosyl]-N6-benzoyladenine 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 TNU1629,CAS号为 325683-88-3。 | |||
TNU1140 |
6-Chloro-9-[2-O-acetyl-5-O-(p-toluoyl)-3-azido-3-deoxy-beta-L-ribofuranosyl]-9H-purine
|
Others | Others |
Nucleoside Derivatives - L-Nucleosides, Azido-nucleosides, Halo-nucleosides; Scaffolds and Templates | |||
TNU1645 |
2-Acetylamino-1-{3’-O-[(4,4’-dimethoxy triphenyl)methyl]-a-L-threo furanosyl}-6-(N,N-diphenylcarbamoyloxy)-9H-purine
|
Others | Others |
2-Acetylamino-1-{3’-O-[(4,4’-dimethoxy triphenyl)methyl]-a-L-threo furanosyl}-6-(N,N-diphenylcarbamoyloxy)-9H-purine 是一种核苷类似物,在生命科学相关研究中具有广泛的应用。 | |||
TNU1633 |
DMTr-TNA-A(Bz)-amidite; 1-{2’-O-[(2-Cyanoethoxy)(diisopropyl amino)phosphino]-3’-O-[(4,4’-dimethoxytriphenyl)methyl]-a-L-threofuranosyl}-N6-benzoyladenine
|
Others | Others |
DMTr-TNA-A(Bz)-amidite; 1-{2’-O-[(2-Cyanoethoxy)(diisopropyl amino)phosphino]-3’-O-[(4,4’-dimethoxytriphenyl)methyl]-a-L-threofuranosyl}-N6-benzoyladenine 是一种核苷类似物,在生命科学相关研究中具有广泛的应用。 | |||
TNU1646 |
DMTr-TNA-G(O6-CONPh2)(N2Ac)-amidite
|
Others | Others |
DMTr-TNA-G(O6-CONPh2)(N2Ac)-amidite 是一种核苷类似物,在生命科学相关研究中具有广泛的应用。 | |||
T67508 |
(2S,4aR,4bS,6aS,7aS,8aS,8bS,8cR,8dR,9aR,9bR)-2,9b-Dihydroxy-4a,6a-dimethylhexadecahydro-1H-cyclopropa[4,5]cyclopenta[1,2-a]cyclopropa[l]phenanthren-7(7aH)-one
|
Others | Others |
(2S,4aR,4bS,6aS,7aS,8aS,8bS,8cR,8dR,9aR,9bR)-2,9b-Dihydroxy-4a,6a-dimethylhexadecahydro-1H-cyclopropa[4,5]cyclopenta[1,2-a]cyclopropa[l]phenanthren-7(7aH)-one 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T67508,CAS号为 82543-16-6。 | |||
T6861 |
IMR-1
|
Gamma-secretase | Neuroscience; Proteases/Proteasome; Stem Cells |
IMR1 是一种Notch 抑制剂,IC50=26 μM。它能够阻止 Maml1 募集到染色质上的 Notch 三元复合体 (NTC),抑制 Notch 靶基因转录,具有抗肿瘤活性。 | |||
T3540 |
IMR-1A
|
Gamma-secretase; Drug Metabolite | Metabolism; Neuroscience; Proteases/Proteasome; Stem Cells |
IMR-1A 是 IMR-1 的酸代谢物。IMR-1A 是 Notch 抑制剂,IC50=0.5 μM。IMR-1A 相对于 IMR-1 的效力提高了 50 倍。 | |||
TP2056L |
Acetyl-Calpastatin (184-210)(human) acetate
Acetyl-Calpastatin (184-210) (human) acetate(123714-50-1 Free base ) |
Cysteine Protease | Proteases/Proteasome |
Acetyl-Calpastatin (184-210)(human) acetate 是一种有效,选择性和可逆的钙蛋白酶 (calpain) 抑制剂,对 μ-钙蛋白酶和组织蛋白酶 L 的 Ki 值分别为 0.2 nM 和 6 μM。 | |||
T37739 |
N-decanoyl-L-Homoserine lactone
C10-HSL,N-decanoyl-L-Homoserine lactone |
Reactive Oxygen Species; Antibacterial | Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB |
N-decanoyl-L-Homoserine lactone (C10-HSL) 是一种由克雷莫里色假单胞菌菌株 ND07产生的 N-acyl-homoserine lactone (AHL)。N-decanoyl-L-homoserine lactone 可抑制拟南芥的主根生长。N-decanoyl-L-homoserine lactone 处理可引起拟南芥根胞质游离 Ca2+ 和活性氧 (ROS) 浓度短暂和和立即升高,增加丝裂原激活蛋白激酶 6 (MPK6) 的活性,并促使一氧化氮 (NO) 的产生。 | |||
T15697 |
L-NMMA acetate
Tilarginine acetate,Methylarginine acetate |
NOS | Immunology/Inflammation |
L-NMMA acetate (Tilarginine acetate) 是一氧化氮合酶抑制剂, 对其所有亚型均有抑制作用,包括 NOS1,NOS2和 NOS3。与 nNOS (大鼠), eNOS (人), 和 iNOS (小鼠)结合 的 Ki 值分别为0.18,0.4,6 µM。 | |||
T11717 |
JHU395
|
Apoptosis | Apoptosis |
JHU395 是一种口服生物利用度高的前药,其活性成分是亲脂性谷氨酸拮抗剂(GA,6-叠氮-5-酮-L-去亚硝基赖氨酸)。JHU395 能有效地将DON输送至恶性周围神经鞘瘤(MPNST)的体外和体内模型中,并在MPNST上显现出显著的抗肿瘤活性。此外,JHU395在血浆中表现出良好的稳定性。 | |||
T7159 |
L-165041
|
PPAR | DNA Damage/DNA Repair; Metabolism |
L-165041 是一种细胞渗透性 PPARδ激动剂,可在 NIH-PPARδ 细胞中诱导脂肪细胞分化,对 PPARδ 和 PPARγ 的 Ki 值分别为 6 nM 和 约 730 nM。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T8373 |
6-Diazo-5-oxo-L-nor-Leucine
DON,L-6-Diazo-5-oxonorleucine,6-重氮-5-氧代-L-正亮氨酸,Diazooxonorleucine |
Influenza Virus; Glutaminase; Antibacterial; Antibiotic | Microbiology/Virology; Proteases/Proteasome |
6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine) 是一种谷氨酰胺拮抗剂,具有抗菌、抗病毒和抗癌作用,其Ki 值为 6 μM。它能降低肿瘤细胞的自我更新能力和转移能力 ,在体外表现出遗传毒性。 | |||
TN2125 |
Quercetin 3-O-β-D-(6''-p-coumaroyl)glucopyranosyl(1→2)-α-L-rhamnopyranoside
3-O-{2-O-[6-O-(P羟基-反-香豆酰)-葡萄糖基]-鼠李糖基}槲皮素,Quercetin 3-O-beta-(6''-p-coumaroyl)glucopyranosyl(1->2)-alpha-L-rhamnopyranoside |
Antioxidant | oxidation-reduction |
Quercetin 3-O-β-D-(6''-p-coumaroyl)glucopyranosyl(1→2)-α-L-rhamnopyranoside (Quercetin 3-O-beta-(6''-p-coumaroyl)glucopyranosyl(1->2)-alpha-L-rhamnopyranoside) 是一种从银杏叶中提取出来的化合物。Quercetin 3-O-β-D-(6''-p-coumaroyl)glucopyranosyl(1→2)-α-L-rhamnopyranoside 具有抗氧化的功能。 | |||
T5120 |
Rhamnose
6-Deoxyhexopyranose,L-鼠李糖,6-Deoxy-L-mannose,alpha-L-Rhamnose |
Calcium Channel; Endogenous Metabolite | Membrane transporter/Ion channel; Metabolism |
alpha-L-Rhamnose (6-Deoxy-L-mannose) 是存在植物和细菌中的一种单糖。Rhamnose- 免疫原连接物能被用于免疫疗法。Rhamnose 能通过胞外途径穿过上皮细胞,能够作为肠吸收的标志。 | |||
T7597 |
6-Biopterin
L-生物喋呤,L-Biopterin |
Endogenous Metabolite; NO Synthase; NOD | Immunology/Inflammation; Metabolism; NF-κB |
6-Biopterin (L-Biopterin) 是一种蝶呤衍生物,是一氧化氮合酶 (NO synthase) 辅因子。 | |||
T2928 |
α-L-Rhamnose monohydrate
L-Rhamnose monohydrate,L-鼠李糖单水合物,6-deoxy-L-mannose monohydrate,α-L-鼠李糖一水合物 |
Others | Others |
α-L-Rhamnose monohydrate (6-deoxy-L-mannose monohydrate) 是植物细胞壁果胶多糖鼠李糖半乳糖醛酸聚糖 1 、鼠李糖半乳糖醛酸聚糖 2 的组分。它也是细菌多糖的组分之一,在致病性方面起重要作用。 | |||
TJO2691 |
(-)-Fucose
L-岩藻糖,Madecassic acid,L-(-)-Fucose,L-Galactomethylose,Brahmic acid,6-Desoxygalactose |
Endogenous Metabolite; Parasite | Metabolism; Microbiology/Virology |
(-)-Fucose (6-Desoxygalactose) 是己糖中的一种,有抗感染、抗癌、增强免疫力、皮肤保湿和延缓皮肤衰老作用。 | |||
T83876 |
L-Ascorbic Acid 6-stearate
L-Ascorbyl-6-stearate,6-O-Stearoyl-L-Ascorbic Acid |
Others | Others |
L-抗坏血酸6硬脂酸酯是L-抗坏血酸与硬脂酸的衍生物,在K. coccinea中发现,具有抗氧化和抗癌作用。在细胞外试验中清除DPPH(IC50 = 3.31 µg/ml)。包裹L-抗坏血酸6硬脂酸酯的脂质纳米颗粒(LNPs)在190 µM浓度下诱导HL-60前髓母细胞凋亡。含有L-抗坏血酸6硬脂酸酯的配方已用于化妆品和个人护理产品中。 | |||
T4856 |
Acetyl-L-lysine
N-乙酰-L-赖氨酸,Nα-Acetyl-L-lysine,(2S)-2-Acetamido-6-aminohexanoic acid |
Endogenous Metabolite | Metabolism |
Acetyl-L-lysine (Nα-Acetyl-L-lysine) 是一种 N-乙酰化氨基酸。它是人类尿液中的一种正常成分,在正常样本中的浓度太小,无法进行常规检测;然而,在一名氨基酰化酶I缺乏症患者的尿液中发现其水平升高。 | |||
TN7112 |
(25R)-3β,17α-dihydroxy-5α- spirostan-6-one3-O-α-L- rhamnopyranosyl-(1→2)-β- D-glucopyranoside
|
Others | Others |
(25R)-3β,17α-dihydroxy-5α- spirostan-6-one3-O-α-L- rhamnopyranosyl-(1→2)-β- D-glucopyranoside 是从百合 Lilium brownii var. viridulum 茎中分离得到的天然产物 | |||
T2758 |
Madecassic acid
6-Deoxy-L-Galactose,羟基积雪草酸,L-Fucose,Brahmic acid,L-fucopyranose |
Others; TNF; COX; NO Synthase; Interleukin | Apoptosis; Immunology/Inflammation; Neuroscience; Others |
Madecassic acid (L-fucopyranose) 是分离自积雪草的一种天然产物,抑制iNOS、COX-2、TNF-α、IL-1beta 和IL-6,可通过在 RAW 264.7 巨噬细胞中下调NF-κB 激活而具有抗炎作用。 | |||
TN1394 |
Apigenin6-C-α-L-arabinopyranosyl-8-C-β-D-xylopyranoside
Apigenin 6-C-alpha-L-arabinopyranosyl-8-C-beta-D-xylopyranoside,芹菜素-6-C-Α-L-吡喃阿拉伯糖-8-C-Β-D-吡喃木糖苷,apigenin6-c-alpha-l-arabinopyranosyl-8-c-beta-d-xylopyranoside |
Others | Others |
Apigenin 6-C-alpha-L-arabinopyranosyl-8-C-beta-D-xylopyranoside is a natural product from Viola yedoensis. | |||
TN6326 |
Neochlorogenin 6-O-α-L-rhamnopyranosyl-(1→3)-β-D-quinovopyranoside
|
||
Neochlorogenin 6-O-α-L-rhamnopyranosyl-(1→3)-β-D-quinovopyranoside 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6326,CAS号为 184686-01-9。 | |||
TN6460 |
Kaempferol-3-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside
Kaempferol-3-O-α-L-rhamnopyranosyl-(1->6)-β-D-glucopyranosyl-(1->2)-β-D-glucopyranoside |
||
Kaempferol-3-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside shows antioxidant activity. | |||
TN1447 |
L-Borneol 7-O-[β-D-apiofuranosyl-(1→6)]-β-D-glucopyranoside
FT-0775891,Borneol 7-O-[beta-D-apiofuranosyl-(1->6)]-beta-D-glucopyranoside,龙脑 7-O-[Β-D-呋喃芹菜糖基-(1→6)]-Β-D-吡喃葡萄糖苷 |
Others | Others |
Borneol 7-O-[beta-D-apiofuranosyl-(1->6)]-beta-D-glucopyranoside is a natural product from Radix ophiopogonis. | |||
T37298 |
Spinacine
|
Endogenous Metabolite | Metabolism |
Spinacine 是人内源性代谢产物。 | |||
TN6399 |
1-(3',5'-dimethoxy)phenyl-2-[4''-O-beta-D-glucopyranosyl (6->1)-O-alpha-L-rhamnopyranosyl]phenylethane
|
||
1-(3',5'-dimethoxy)phenyl-2-[4''-O-β-D-glucopyranosyl (6→1)-O-α-L-rhamnopyranosyl]phenylethane showed cytotoxic activities to Hela and hep2 cell lines. | |||
TN2119 |
Pulsatilla saponin H
白头翁属皂苷H,白头翁皂苷 H,3-O-Β-D-葡萄糖( 1→4)-[ A -L-鼠李糖(1→2)]- A-L-阿拉伯糖 常春藤配基- 28-O-鼠李糖(1→4)葡萄糖(1→6)葡萄糖苷 |
Others | Others |
Pulsatilla saponin H 是一种从 Pulsatilla koreana 的根中分离出来的天然产物。 | |||
TN2117 |
Pulsatilloside E
3-O-B-D-葡萄糖( 1→4)-[ A -L-鼠李糖(1→2)]- A-L-阿拉伯糖 23-羟基羽扇豆20(29)-烯-28–酸- 28-O-鼠李糖(1→4)葡萄糖(1→6)葡萄糖苷,Pulchinenoside E,白头翁皂苷E |
Others | Others |
Pulsatilloside E (Pulchinenoside E) 是一种从毛茛科白头翁Pulsatilla chinensis (Ranunculaceae)的根中分离出来的天然产物。 | |||
T83325 |
4-Aminophenyl 6-deoxy-α-L-mannopyranoside
|
||
4-Aminophenyl 6-deoxy-α-L-mannopyranoside为油茶种子可分离的糖苷类化合物。 | |||
TN1822 |
Kaempferol-3-O-(6'''-trans-p-coumaroyl-2''-glucosyl)rhamnoside
3-O-{2-O-[6-O-(P羟基-反-香豆酰)-葡萄糖基]-鼠李糖基}山奈酚,kaempferol-3-o-6-trans-p-coumaroyl-2-glucosyl-rhamnoside,Kaempferol 3-O-beta-(6''-p-coumaroyl)glucopyranosyl(1->2)-alpha-L-rhamnopyranoside |
Others | Others |
Kaempferol 3-O-beta-(6''-p-coumaroyl)glucopyranosyl(1->2)-alpha-L-rhamnopyranoside is a natural product | |||
TN5491 |
2"-O-Glucosylrutin
Quercetin 3-O-β-D-glucopyranosyl(1→2)[α-L-rhamnopyranosyl(1→6)]-β-D-glucopyranoside |
||
2"-O-Glucosylrutin 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5491,CAS号为 55696-55-4。 | |||
T83253 |
7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol
|
||
7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol为一种香豆精苷,可自Rhodiola rosea提取。 | |||
T83210 |
Acacetin 7-O-(6′′-O-α-L-rhamnopyranosyl-β-sophoroside)
|
||
Acacetin 7-O-(6′′-O-α-L-rhamnopyranosyl-β-sophoroside)为从Valeriana jatamansi Jones中提取的黄酮苷类化合物。 | |||
T83323 |
4-Chloro-3-methoxy-5-methylphenyl 6-O-(6-deoxy-β-L-mannopyranosyl)-β-D-glucopyranoside
|
Others | Others |
化合物3(4-Chloro-3-methoxy-5-methylphenyl 6-O-(6-deoxy-β-L-mannopyranosyl)-β-D-glucopyranoside)是一种从Lilium regale提取的抗癌天然产物,具有显著抑制肺癌A549细胞增殖的活性,显示出其研究癌症治疗潜力。 | |||
T81902 |
Luteolin-7-O-α-L-arabinopyranosyl (1→6)-β-D-glucopyranoside
|
||
Luteolin-7-O-α-L-arabinopyranosyl (1→6)-β-D-glucopyranoside 是一种黄酮类化合物,具有抗自由基活性。 | |||
T82985 |
Apigenin-6-C-β-D-xylopyranosyl-8-C-α-L-arabinopyranoside
|
||
Apigenin-6-C-β-D-xylopyranosyl-8-C-α-L-arabinopyranoside,一类黄酮化合物,具抗氧化活性,源自中药铁皮石斛。 | |||
TN1201 |
25(S)-Ruscogenin-1-O-α-L-rhamnopyranosyl (1→2)-β-D-xylopyranoside
25(S)-鲁斯可皂苷元-1-O-Α-L-吡喃鼠李糖基-(1→2)-Β-D-吡喃木糖苷,山麦冬皂苷C,(1beta,3beta,25S)-3-Hydroxyspirost-5-en-1-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-xylopyranoside |
Others | Others |
(1beta,3beta,25S)-3-Hydroxyspirost-5-en-1-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-xylopyranoside is a natural product | |||
TN1167 |
2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone-3-O-α-rhamnosyl-(1→2)-β-D-glucoside
1,3,6-Trihydroxy-2-methylanthraquinone 3-O-(6'-O-acetyl)-alpha-L-rhamnosyl-(1->2)-Beta-D-glucoside,1,3,6-三羟基-2-甲基蒽醌-3-O-Α-鼠李糖-(1→2)-Β-D-(6'-O-乙酰基)-葡萄糖苷 |
Antifection | Microbiology/Virology |
1,3,6-Trihydroxy-2-methylanthraquinone 3-O-(6'-O-acetyl)-alpha-L-rhamnosyl-(1->2)-Beta-D-glucoside shows certain antibacterial activity. | |||
T83345 |
3-O-α-L-Rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl hederagenin28-O-β-D-xylopyranosyl-(1→6)-β-D-glucopyranosyl ester
|
||
3-O-α-L-Rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl hederagenin 28-O-β-D-xylopyranosyl-(1→6)-β-D-glucopyranosyl ester 是一种皂苷化合物,具备抗肿瘤与抗炎特性。 | |||
T83209 |
Acacetin 7-O-β-D-glucuronopyranosyl-(1→2)[α-L-rhamnopyranosyl-(1→6)]-β-D-glucopyranoside
|
||
Acacetin 7-O-β-D-glucuronopyranosyl-(1→2)[α-L-rhamnopyranosyl-(1→6)]-β-D-glucopyranoside (compound 8) 是一款从刺槐 (Leguminosae) 叶提取物中分离出的黄酮苷。 | |||
T83208 |
Acacetin 7-O-β-D-xylopyranosyl-(1→2)[α-L-rhamnopyranosyl-(1→6)]-β-D-glucopyranoside
|
||
Compound 10,即Acacetin 7-O-β-D-xylopyranosyl-(1→2)[α-L-rhamnopyranosyl-(1→6)]-β-D-glucopyranoside,是一种从刺槐叶提取物中分离的黄酮苷。 | |||
TN6775 |
Acetylcytisine
1,5-Methano-8H-pyrido[1,2-a][1,5]diazocin-8-one,3-acetyl-1,2,3,4,5,6-hexahydro-, (1R)-,11-Acetyl-6-oxo-7,11-diazatricyclo[7.3.1.0<2,7>]trideca-2,4-diene |
Others | Others |
Acetylcytisine (11-Acetyl-6-oxo-7,11-diazatricyclo[7.3.1.0<2,7>]trideca-2,4-diene) 是 Genista tinctoria L. 草药的天然产物。 | |||
T124477 |
Resveratrol 4'-(6-galloylglucoside)
Resveratrol-4'-O-(6"-galloyl)glucoside |
Others | Others |
Resveratrol 4'-(6-galloylglucoside) (Resveratrol-4'-O-(6"-galloyl)glucoside)是一种天然产物,存在于植物掌叶大黄 rhubarb (Rheum palmatum L.)的根中。 | |||
T3S1967 |
(S)-Indoximod
N-ME-Tryptophan,Abrine,相思豆碱,L-Abrine |
Others; Indoleamine 2,3-Dioxygenase (IDO) | Metabolism; Others |
(S)-Indoximod (L-Abrine) 是一种吲哚胺-2,3-双加氧酶 (IDO) 抑制剂,可用于研究癌症。 | |||
T5066 |
Nε,Nε,Nε-Trimethyllysine chloride
Lys(Me)3-OH Chloride,Nε,Nε,Nε-Trimethyllysine hydrochloride |
Others; Endogenous Metabolite | Metabolism; Others |
Nε,Nε,Nε-Trimethyllysine chloride (Lys(Me)3-OH Chloride) 是肠道菌群依赖性形成 N,N,N-trimethyl-5-aminovaleric acid (TMAVA) 的前体。 | |||
T3809 |
Liriope muscari baily saponins C
|
Others | Others |
Liriope muscari baily saponins C 是一种L. muscari (Decne.) Baily 的主要活性成分。它已被作为肿瘤转移候选药物进行研究。它具有很强的抗炎、免疫药理和心脏保护作用。 | |||
T3398 |
Icaritin
Anhydroicaritin,去水淫羊藿黄素,Cycloicaritin |
Apoptosis; JAK; STAT; Autophagy | Angiogenesis; Apoptosis; Autophagy; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells |
Icaritin (Anhydroicaritin) 是Epimedium Genusis 的异戊二烯类黄酮衍生物,有效抑制 K562 细胞和原代 CML 细胞的增殖。它可以调节MAPK/ERK/JNK 和JAK2/STAT3/AKT 信号传导,并具有增强成骨的作用。 | |||
T5558 |
Chelidonic acid
Jervaic acid,Jerva acid,白屈菜酸,γ-Pyrone-2,6-dicarboxylic acid |
NF-κB; Caspase | Apoptosis; NF-κB; Proteases/Proteasome |
Chelidonic acid (Jervaic acid) 是从白屈菜中分到的酸类物质,用作温和的镇痛剂、抗菌剂和中枢神经系统镇静剂。它是谷氨酸脱羧酶抑制剂,Ki 值为 1.2 μM。它可能通过抑制 NF-κB 和caspase-1来降低 IL-6 的产生抗炎作用。 | |||
T4S1962 |
beta-Asarone
β-细辛脑,(Z)-1,2,4-三甲氧基-5-丙烯基苯;顺式细辛脑,Cis-Isoasarone,Cis-Asarone,Cis-Isoelemicin |
NF-κB; JNK | MAPK; NF-κB |
beta-Asarone (Cis-Isoelemicin) 是一种石菖蒲中的主要成分,具有免疫抑制、促进安定、中枢神经系统抑制、降温等功能。它可透过血脑屏障,能够预防帕金森病。 | |||
TN1314 |
6-Hydroxykaempferol
|
Tyrosinase | Proteases/Proteasome |
6-Hydroxykaempferol is a competitive inhibitor of tyrosinase compared to L-DOPA, it shows also high antioxidant activities. | |||
TN3171 |
6-Hydroxy-1,2,3,7-tetramethoxyxanthone
|
Others | Others |
6-Hydroxy-1,2,3,7-tetramethoxyxanthone is a natural product from Polygala sibirica L. | |||
TN6290 | Stephalonine L | ||
Stephalonine L 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6290,CAS号为 2379277-60-6。 | |||
TN4685 |
O-Acetylschisantherin L
|
Others | Others |
O-Acetylschisantherin L 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN4685,CAS号为 149998-51-6。 | |||
TN1426 |
Baicalein 6-O-glucoside
|
Others | Others |
Baicalein 6-O-glucoside is a natural product from Thymus serpyllum L. | |||
T82724 |
Chrysophanol 8-O-β-D-(6′-O-galloyl)glucopyranoside
|
||
Chrysophanol 8-O-β-D-(6’-O-galloyl)glucopyranoside为一种从Rheum undulatum L. 分离得到的蒽醌类葡萄糖苷,具备显著的DPPH自由基与?O2-清除作用。 | |||
TN5468 |
Epimedonin L
|
||
Epimedonin L 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5468,CAS号为 2215102-38-6。 | |||
T65246 |
L-Prolylglycine
|
Others | Others |
L-Prolylglycine 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 T65246,CAS号为 2578-57-6。 | |||
TN6445 |
Cyclo(Gly-L-Pro)
|
||
Cyclo(Gly-(L)-Pro) shows immunostimulatory properties. Cyclo(Gly-l-Pro) exhibits potent inhibition of TNF-α release with the IC50 values of 4.5 ug/mL, respectively, it also exhibits significant diminution of IL-1β and IL-6 mRNA-expression levels and NO pr | |||
T39168 |
Epsilon-(gamma-glutamyl)-lysine
Epsilon-(gamma-glutamyl)-lysine,γ-Glu-ε-Lys,H-Glu(H-Lys-OH)-OH |
Others | Others |
Epsilon-(gamma-glutamyl)-lysine is an N(6)-acyl-L-lysine derivative that forms bonds between extracellular matrix (ECM) components with the assistance of the enzyme tissue transglutaminase (tTg). These bonds are implicated in the pathogenesis of certain diseases like non-diabetic kidney and glaucoma filtration. | |||
T81322 |
Quercetin-3-O-[(6-caffeoyl)-β-glucopyranosyl (1→3) α-rhamnopyranoside]-7-O-α-rhamnopyranoside
|
||
Quercetin-3-O-[(6-caffeoyl)-β-glucopyranosyl (1→3) α-rhamnopyranoside]-7-O-α-rhamnopyranoside,一种具备伤口愈合活性的化合物,可从Ophioglossum vulgatumL地上部分分离得到。 | |||
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Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03956 |
Fas Ligand Protein, Human, Recombinant (His)
TNLG1A,FASL,FASLG,CD178,CD95-... |
Human | P. pastoris (Yeast) |
Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Fas Ligand Protei... | |||
TMPK-00865 |
TM4SF1 Protein-VLP, Human, Recombinant
TAAL6,L6,H-L |
Human | HEK293 Cells |
Transmembrane-4-L-six-family-1(TM4SF1), a four-transmembrane L6 family member, is highly expressed in various pancreatic cancer cell lines and promotes cancer cells metastasis. It is upregulated in several epithelial cancers and is closely associated with poor prognosis. | |||
TMPY-02595 |
DUSP14 Protein, Human, Recombinant (His & MBP)
MKP6,MKP-L,dual specificity phosp... |
Human | E. coli |
Dual specific phosphatase 14 / MAP-kinase phophatase-6 (DUSP14 / MKP6) is a member of Dual-specificity phosphatases that is a subclass of protein tyrosine phosphatases (PTP) families that can dephosphorylate bothe phosphotyrosine and phosphoserine / phosphothreonine residues in substrates. Unlike many other DUSPs, DUSP14 only contains a catalytic domain within the C-terminal region. In signal transduction, DUSP14 has been considered as negative regulator of the mitogen-activated protein kinase (... | |||
TMPY-05399 |
Human Papilloma Virus type 6 (HPV 6) L1 Protein-VLP
|
HPV | Baculovirus Insect Cells |
Human Papilloma Virus type 6 (HPV 6) L1 Protein-VLP is expressed in Baculovirus insect cells. The predicted molecular weight is 55 kDa. | |||
TMPK-00992 |
SEZ6L2 Protein, Mouse, Recombinant (His)
SEZ6L2,BSRP-A,PSK-1,UNQ1903/PRO4349 |
Mouse | HEK293 Cells |
Seizure-related 6 homolog (mouse)-like 2 (SEZ6L2) was shown to be involved in transcription of a type 1 transmembrane protein for regulating cell fate. SEZ6L2 was significantly up-regulated in tumour tissues of patients with CRC compared with adjacent normal tissues. Up-regulation of SEZ6L2 was correlated with a poor prognosis in patients with CRC. Furthermore, SEZ6L2 expression was inversely correlated with the expression of cytochrome C in malignant tissues in patients with CRC. | |||
TMPY-03856 |
SEZ6L2 Protein, Human, Recombinant (His)
PSK-1,seizure related 6 homolog (... |
Human | HEK293 Cells |
SEZ6L2, also known as PSK-1, belongs to the SEZ6 family. It contains 3 CUB domains and 5 Sushi (CCP/SCR) domains. SEZ6L2 may contribute to specialized endoplasmic reticulum functions in neurons.SEZ6L2 presents on the surface of lung cancer cells. SEZ6L2 should be a useful prognostic marker of lung cancers. Increased expression of this gene has been found in lung cancers, and the protein is therefore considered to be a novel prognostic marker for lung cancer. | |||
TMPY-02842 |
UBE2L6 Protein, Human, Recombinant (His)
UBCH8,ubiquitin-conjugating enzyme E2L 6,R... |
Human | E. coli |
UBCH8, also known as UBE2L6, belongs to the ubiquitin-conjugating enzyme family. The family of ubiquitin-conjugating (E2) enzymes is characterized by the presence of a highly conserved ubiquitin-conjugating (UBC) domain. These domains accommodate the ATP-activated ubiquitin (Ub) or ubiquitin-like (UBL) protein via a covalently linked thioester onto its active-site residue. E2 enzymes act via selective protein-protein interactions with the E1 and E3 enzymes and connect activation to covalent modi... | |||
TMPJ-01111 |
TSTA3 Protein, Human, Recombinant (His)
GDP-L-Fucose Synthase,Short-Chain Dehydrogenase/Red... |
Human | E. coli |
GDP-L-Fucose Synthase is a NADP(H)-binding protein. It catalyzes the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-dexoymannose to GDP-L-fucose. GDP-L-Fucose is the substrate of several fucosyltransferase, involving the expression of mamy glycoconjugates, including blood group ABH antigens and development adhesion antigens. Mutations in the TSTA3 gene may cause leukocyte adhesion deficiency type II. | |||
TMPJ-00872 |
MGMT Protein, Human, Recombinant (His)
MGMT,6-O-methylguanine-DNAmethylt... |
Human | E. coli |
MGMT belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. MGMT involved in the cellular defense against the biological effects of O6-methylguanine in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. MGMT catalyzes the chemical reaction: DNA (containing 6-O-methylguanine) and proteinL-cysteine into DNA (without 6-O-methylguanine) and protein S-met... | |||
TMPJ-00514 |
ACPP Protein, Human, Recombinant (His)
Ecto-5'-Nucleotidase,TMPase,5'-Nucleotidas... |
Human | HEK293 Cells |
Prostatic Acid Phosphatase (PAP) belongs to the histidine acid phosphatase family. PAP can catalyze the hydrolysis of member of phosphate monoestyers, including phosphorylated protein. PAP can high expression in metastasized prostate cancer, moderately expression level in bone diseases, blood cell disease, and the concentration of PAP is used to monitor and assess the proession of prostate cancer. The optimum PH of PAP is from 4 to 6; its activity can be inhibited by L(+)-tartrate. | |||
TMPY-01189 |
GFPT1 Protein, Human, Recombinant
GFAT1,CMSTA1,GFAT,glutamine--fructose-6-ph... |
Human | E. coli |
Glutamine:fructose-6-phosphate amidotransferase 1 (GFAT), also known as GFPT1, is a member of the N-terminal nucleophile aminotransferases and the first rate-limiting enzyme for the entry of glucose into the hexosamine biosynthesis pathway (HBP) in mammals. GFAT transfers the amino group from the L-glutamine amide to the D-fructose 6-phosphate, producing glutamic acid and glucosamine 6-phosphate. GFAT exists as a homotetramer in cytoplasm, and is proposed to be most likely involved in re... | |||
TMPJ-00567 |
NCR1 Protein, Human, Recombinant (hFc)
hNKp46,Natural cytotoxicity triggering rec... |
Human | HEK293 Cells |
Natural cytotoxicity triggering receptor 1(NCR1) is a single-pass type I membrane protein .It contains 2 Ig-like (immunoglobulin-like) domains and belongs to the natural cytotoxicity receptor (NCR) family. The protein is a natural killer (NK) lymphocyte-activating receptor. It is involved in major aspects of NK immune function and shows a high degree of lineage specificity in blood and bone marrow. | |||
TMPY-03128 |
LAIR1 Protein, Mouse, Recombinant (hFc)
leukocyte-associated immunoglobul... |
Mouse | HEK293 Cells |
LAIR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.6 kDa and the accession number is Q8BG84-6. | |||
TMPJ-00827 |
Tau-D Protein, Human, Recombinant (His)
PHF-Tau,MAPTL,MAPT,Paired Helical... |
Human | E. coli |
Microtubule-Associated Protein TAU is abundantly expressed in neurons of the central nervous system and less commonly expressed elsewhere, but is also expressed at very low levels in CNS astrocytes and oligodendrocytes. Tau interacts with tubulin to stabilize microtubules and promotes tubulin assembly into microtubules. The C-terminus of TAU binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau acts as a linker protein. When tau is defective,... | |||
TMPY-05798 |
VEGF145 Protein, Human, Recombinant
血管内皮生长因子,vascular endothelial gro... |
Human | HEK293 Cells |
VEGF145 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 16.92 kDa and the accession number is P15692-6. | |||
TMPY-04277 |
CD45 Protein, Mouse, Recombinant (hFc)
Cd45,protein tyrosine phosphatase, receptor type, C,L |
Mouse | HEK293 Cells |
CD45 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.7 kDa and the accession number is P06800-6. | |||
TMPY-02600 |
NRG1 beta 1 Protein, Human, Recombinant (EGF Domain, hFc)
neuregulin 1,HRGA,NRG1 β1,HGL,MST131,MSTP1... |
Human | HEK293 Cells |
NRG1 beta 1 Protein, Human, Recombinant (EGF Domain, hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 36.7 kDa and the accession number is Q02297-6. | |||
TMPY-02705 |
NRG1 beta 1 Protein, Human, Recombinant (hFc)
MSTP131,HRG1,NRG1-IT2,ARIA,HGL,SMDF,GGF,HRG,NDF,MST... |
Human | HEK293 Cells |
NRG1 beta 1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 55.2 kDa and the accession number is Q02297-6. | |||
TMPY-03010 |
NRG1 beta 1 Protein, Human, Recombinant
NDF,GGF,MSTP131,Neuregulin 1,MST131,ARIA,NRG1-IT2,S... |
Human | HEK293 Cells |
NRG1 beta 1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.8 kDa and the accession number is Q02297-6. | |||
TMPK-00614 |
NKp46/NCR1 Protein, Human, Recombinant (His)
NKp46,MAR-1,Ly94,NCR1,NKP46FL... |
Human | HEK293 Cells |
NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expressed almost exclusively by NK cells and play a major role in triggering some of the key lytic activities of NK cells. NKp46/NCR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 27.5 kDa and the accession numb... | |||
TMPK-00615 |
NKp46/NCR1 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
CD335,NCR1,NKp46,NKP46FLJ99094, |
Human | HEK293 Cells |
NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expressed almost exclusively by NK cells and play a major role in triggering some of the key lytic activities of NK cells. NKp46/NCR1 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular we... | |||
TMPK-01364 |
SIRP alpha V6 Protein, Human, Recombinant (His & Avi), Biotinylated
SIRP α,MFR,SHPS1,SIRPA,BIT,SHPS-1,MYD-1,SIRP alpha,... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V6 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c... | |||
TMPK-01358 |
SIRP alpha V6 Protein, Human, Recombinant (His & Avi)
P84,SIRPA,SIRP alpha,SHPS-1,MFR,BIT,MYD1,SIRP α V |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V6 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-Hi... |
Cat. No. | Product Name | Target | Signaling Pathways |
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TMIJ-0378 |
L-Ascorbic Acid-13C6
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L-Ascorbic Acid-13C6 是 L-Ascorbic Acid 的 13C 的标记化合物。L-Ascorbic Acid 的 CAS 号为 50-81-7。L-Ascorbic acid是一种电子供体,是一种内源性抗氧化剂。它选择性抑制 Cav3.2 通道,IC50为 6.5 μM。它还是一种胶原沉积促进剂和弹性生成抑制剂,可对抗细菌感染、解毒反应和胶原蛋白的形成。 | |||
TMID-0151 |
5-Hydroxy-L-tryptophan-4,6,7-d3
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5-Hydroxy-L-tryptophan-4,6,7-d3 是 5-Hydroxy-L-tryptophan 的氘代化合物。5-Hydroxy-L-tryptophan 的 CAS 号为 314062-44-7。 | |||
TMIJ-0380 |
L-Lysine-13C6-15N2 Hydrochloride
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L-Lysine-13C6-15N2 Hydrochloride 是 L-Lysine Hydrochloride 的 13C 和 15 N 的标记化合物。L-Lysine Hydrochloride 的 CAS 号为 657-27-2。L-lysine hydrochloride 是一种人类必需氨基酸,能增加钙吸收,减少糖尿病相关疾病和改善肠道健康,可用于疱疹的研究。 | |||
T36384 |
DL-Tyrosine-13C9,15N
L-Tyrosine-13C9,15N |
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L-Tyrosine-13C9,15N is intended for use as an internal standard for the quantification of L-tyrosine by GC- or LC-MS. L-Tyrosine is a non-essential amino acid.1It is produced by hydroxylation of phenylalanine by phenylalanine hydroxylase but can also be obtained from dietary sources or degradation of endogenous proteins, resulting in L-tyrosine release.1,2L-Tyrosine is a precursor in the biosynthesis of catecholamine neurotransmitters, melanins, and thyroid hormones.3Plasma, skeletal muscle, and... | |||
T69995 |
Chlorhexidine-d8 HCl
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Chlorhexidine-d8 is intended for use as an internal standard for the quantification of chlorhexidine by GC- or LC-MS. Chlorhexidine is a bis(biguanide) antimicrobial disinfectant and antiseptic agent. It inhibits growth of clinical methicillin-resistant S. aureus (MRSA) isolates (MIC90 = 4 μg/ml). It is also active against canine isolates of MRSA, methicillin-susceptible S. aureus (MSSA), methicillin-resistant S. pseudintermedius (MRSP), and methicillin-susceptible S. pseudintermedius (MSSP; MIC... |