Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T4517 |
L189
|
DNA; DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
L189 是一种人类 DNA 连接酶抑制剂,抑制 hLigI/III/IV,IC50值分别为5、9 和 5 μM。 | |||
T37187 |
D-erythro/L-threo Lysosphingomyelin (d18:1)
D-erythro/L-threo Lysosphingomyelin (d18:1) |
Others | Others |
Lysosphingomyelin is an endogenous bioactive sphingolipid and a constituent of lipoproteins.1,2It is produced by the removal of the acyl group from sphingomyelin by a deacylase and acts as a precursor in the biosynthesis of sphingosine-1-phosphate . D-erythroLysosphingomyelin is an agonist of the S1P receptors S1P1, S1P2, and S1P3(EC50s = 167.7, 368.1, and 482.6 nM, respectively, for the human receptors).3It is also an agonist of the orphan receptor ovarian cancer G protein-coupled receptor 1 (O... |