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Search Results for " kifunensine "
Targets Recommended: Others

1

抑制剂 & 化合物

1

天然产物

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重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T62198 AR524

Others Others
AR524 是一种转基因抑制剂,抑制活性高于已知的转基因抑制剂 kifunensine。AR524 能够抑制低浓度 (10 μM) 的人类恶性细胞球状体的形成。

化合物

AR524
Cat.No: T62198
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
T20628 Kifunensine

Kifunensine, a potent and selective inhibitor of class I α-mannosidases, may serve as a key inhibitor of glycoprotein biosynthesis. Its inhibitory effect may lead to high mannose glycoproteins in cell culture.

天然产物

Kifunensine
Cat.No: T20628
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPJ-01384 MAN1B1 Protein, Human, Recombinant (His)

ER Alpha-1,Man9GlcNAc2-Specific-Processing Alpha-Mannosidase...

Human HEK293 Cells
Endoplasmic Reticulum Mannosyl-Oligosaccharide 1,2-α-Mannosidase (MAN1B1) belongs to the glycosyl hydrolase 47 family. MAB1B1 is a single-pass type II membrane protein and widely expressed in many tissues. MAB1B1 is involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. MAB1B1 can be inhibited by both 1-deoxymannojirimycin (dMNJ) and kifunensine. Defects in MAN1B1 are the cause of mental retardation autosomal recessive type 15 (MRT15). Mental retardation i...

重组蛋白

MAN1B1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01384
Species: Human
Expression System: HEK293 Cells
TargetMol Loading
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