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Search Results for " ketoconazole "

Targets Recommended: NADPH-oxidase P450 Hydroxylase Antifungal Ras

抑制剂 & 化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T0679	Ketoconazole R-41400,Xolegel,(±)-Ketoconazol,酮康唑,Extina	NADPH-oxidase; P450; Hydroxylase; Antifungal; Ras	GPCR/G Protein; Immunology/Inflammation; MAPK; Metabolism; Microbiology/Virology
	Ketoconazole (R-41400) 是一种咪唑类抗真菌剂，也是一种 CYP3A4 抑制剂。
T21022	Deacylketoconazole Deacyl ketoconazole,脱乙酰酮康唑	Antifungal	Microbiology/Virology
	Deacylketoconazole (Deacyl ketoconazole) 是一种酮康唑衍生物，也是一种抗真菌剂。脱酰基酮康唑对恶性疟原虫的活性是酮康唑的 15 至 50 倍。
T66121	Ketoconazole Intermediate 1e (cis-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate	Others	Others
	Ketoconazole Intermediate 1e ((cis-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate) 是一种酮康唑中间体。
T7824	Eberconazole Nitrate 硝酸依柏康唑,Ebernet	Antifungal	Microbiology/Virology
	Eberconazole Nitrate (Ebernet) 是一种二氯咪唑衍生物，具有抗真菌活性，效果比Ketoconazole、Clotrimazole 和Miconazole 强。它通过局部给药对皮肤癣菌病具有潜在的研究价值。
T72915	Eberconazole	Others	Others
	Eberconazole为一种抗真菌活性的二氯咪唑衍生物。其效果优于Clotrimazole、Ketoconazole及Miconazole。Eberconazole通过局部给药展现对治疗皮肤癣菌病的潜力。
T85120	(±)17(18)-EpETE-Ethanolamide (±)17(18)-EpETE-EA,(±)17,18-EEQ-Ethanolamide,17,18-EEQ-EA,17,18-epoxy-Eicosatetraenoic Acid Ethanolamide	Others	Others
	(±)17(18)-EpETE-Ethanolamide, an ω-3 endocannabinoid epoxide, originates from eicosapentaenoic ethanolamide (EPEA) through cytochrome P450 (CYP) epoxygenases action and is decomposed by soluble epoxide hydrolase (sEH) and fatty acid amide hydrolase (FA, AH). Its endogenous synthesis occurs in LPS-stimulated and EPEA-supplemented BV-2 microglia cells, a process inhibited by the CYP inhibitor ketoconazole. This compound mitigates IL-6 and nitrite levels while enhancing IL-10 production following L...
T21881	Fluconazole hydrate	Others	Others
	Fluconazole 水合物是抗真菌化合物，用于治疗和预防浅表和全身性的真菌感染。

化合物

Ketoconazole

Cat.No: T0679

Synonym: R-41400,Xolegel,(±)-Ketoconazol,酮康唑,Extina

Target: NADPH-oxidase, P450, Hydroxylase, Antifungal, Ras

Deacylketoconazole

Cat.No: T21022

Synonym: Deacyl ketoconazole,脱乙酰酮康唑

Target: Antifungal

Ketoconazole Intermediate 1e

Cat.No: T66121

Synonym: (cis-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate

Target: Others

Eberconazole Nitrate

Cat.No: T7824

Synonym: 硝酸依柏康唑,Ebernet

Target: Antifungal

(±)17(18)-EpETE-Ethanolamide

Cat.No: T85120

Synonym: (±)17(18)-EpETE-EA,(±)17,18-EEQ-Ethanolamide,17,18-EEQ-EA,17,18-epoxy-Eicosatetraenoic Acid Ethanolamide

Cat. No.	Product Name	Target	Signaling Pathways
T13464L	(-)-Ketoconazole (-)-R 41400,(-)-Ketoconazol	Others	Others
	(-)-Ketoconazole is one of the enantiomer of Ketoconazole. Ketoconazole is a racemic mixture of two enantiomers.