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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T84287 |
P3FI-63
|
Histone Demethylase | Chromatin/Epigenetic |
P3FI-63 是一种选择性 KDM3B 抑制剂(IC50:7 μM),具有抗肿瘤活性,可用于研究融合阳性横纹肌肉瘤和其他转录成瘾癌症。 | |||
T9243 |
PFI-90
|
Histone Demethylase; Others | Chromatin/Epigenetic; Others |
PFI-90 是组蛋白去甲基化酶 (KDM3B) 的选择性抑制剂,可抑制 PAX3-FOXO1 的作用。它具有抗肿瘤活性的潜力,可诱导细胞凋亡和成肌分化,导致细胞死亡增加。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01622 |
KDM3B Protein, Human, Recombinant (His & Myc & SUMO)
[histone H3]-dimethyl-L-lysine(9) demethylase 3B,Ly... |
Human | E. coli |
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity. |