Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T24239 |
K201
K-201,JTV 519,JTV-519,K 201 |
Calcium Channel | Membrane transporter/Ion channel; Metabolism |
K201 (JTV-519) 是一种 Ca2+ 依赖性阻滞剂,通过稳定兰尼碱受体来防止缺血性心脏和骨骼肌 (SkM) 中的肌质网异常 Ca(2+) 泄漏。 | |||
T11732 |
JTV-519 hemifumarate
K201 hemifumarate |
MELK | PI3K/Akt/mTOR signaling |
JTV-519 hemifumarate,Antiarrhythmic and cardioprotective properties. is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle. | |||
T11731 |
JTV-519 free base
K201 free base |
FLT | Angiogenesis; Tyrosine Kinase/Adaptors |
JTV-519 free base (K201 free base), recognized for its antiarrhythmic and cardioprotective properties, functions as a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and serves as a partial agonist of ryanodine receptors in striated muscle. | |||
T7360 |
GSK2018682
|
S1P Receptor; LPL Receptor | GPCR/G Protein |
GSK2018682 是 1-磷酸鞘氨醇受体S1P1和S1P5激动剂,pEC50值分别为 7.7 和 7.2,可用于多发性硬化的研究。 | |||
T71564 |
GSK2018682 HCl
|
Others | Others |
GSK2018682 is a novel sphingosine-1-phosphate receptor 1 (s1p1) and 5 (s1p5) agonist. | |||
T37807 |
JTV-519 fumarate
|
Calcium Channel | Membrane transporter/Ion channel; Metabolism |
JTV-519 fumarate (K201 fumarate) 是 一种 SERCA 阻断剂和兰尼碱受体的部分激动剂,具有抗心律失常和心脏保护作用,可改善肌浆网钙渗漏,可用于研究焦虑症。 |