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重组蛋白 细胞因子和生长因子 •   细胞因子 •   生长因子 受体蛋白 •   Fc 受体 •   细胞因子和生长因子受体 •   受体酪氨酸激酶 CD 蛋白 •   T 细胞 CD 蛋白 •   B 细胞 CD 蛋白 免疫检查点蛋白 •   抑制性免疫检查点蛋白 •   刺激性免疫检查点蛋白 CAR-T 细胞治疗靶点蛋白 •   血液恶性肿瘤靶点蛋白 •   实体瘤靶点蛋白
信号通路 血管生成 凋亡 自噬 细胞周期 表观遗传 细胞骨架
DNA损伤和修复 内分泌与激素 G蛋白偶联受体 免疫与炎症 JAK/STAT信号通路 MAPK信号通路 离子通道
代谢 微生物学 神经科学 NF-κB信号通路 氧化还原 PI3K/Akt/mTOR信号通路 蛋白酶体
干细胞 蛋白酪氨酸激酶 泛素化 PROTAC 其他
活性化合物库 上市药物库 临床期小分子药物库 已知活性化合物库 FDA上市及药典收录分子库 抗癌药物库 抗病毒库 铁死亡化合物库
天然产物库 高通量筛选天然产物库 Ro5类药天然产物库 中药单体化合物库 糖类及苷类化合物库 稀有天然产物库 天然产物衍生物库 天然产物单体化合物库
Fragment片段库 高溶解性片段库 精选片段库 高溶解性多官能团片段化合物库 高溶解性卤化片段化合物库 药物片段库 Mini片段亲电杂环化合物库 高溶解性微型片段化合物库
类药性化合物库 多样性核心库Part2 多样性核心库Part1 药物靶点库 多样性核心预制库 Golden骨架库 Mini骨架库 化合物库深度定制
TargetMol Compound Library
天然产物库 高通量筛选天然产物库 特色天然产物库 天然产物衍生物库 虚拟筛选天然产物库
结构类型 萜类 类固醇 类黄酮 醌类 香豆素 木脂素 多糖和糖苷
苯丙烷 生物碱 酚类 其他
植物来源 列当科 水龙骨科 南洋杉科 报春花科 海金沙科 商陆科 买麻藤科
萝藦科 肉豆蔻科 鸭跖草科 交让木科 三白草科 海桐花科 五味子科 红厚壳科
莲叶桐科 胡桃科 石杉科 桔梗科 百合科 忍冬科 漆树科
计算机辅助药物设计 虚拟筛选 分子对接 反向找靶 分子动力学模拟
基于靶点筛选实体化合物活性筛选 分子结合&互作检测 酶学靶点活性检测 核受体靶点活性检测 GPCR靶点活性检测
基于表型筛选实体化合物活性筛选 细胞增殖检测 细胞周期检测 细胞凋亡检测 药代动力学研究
药物设计和结构优化 化合物定制合成 分子砌块 网络药理学平台 软件平台
细胞因子和生长因子 •   细胞因子 •   生长因子 受体蛋白 •   Fc 受体 •   细胞因子和生长因子受体
CD 蛋白 •   T 细胞 CD 蛋白 •   B 细胞 CD 蛋白 免疫检查点蛋白 •   抑制性免疫检查点蛋白 •   刺激性免疫检查点蛋白
CAR-T 细胞治疗靶点蛋白 •   血液恶性肿瘤靶点蛋白 •   实体瘤靶点蛋白 酶 •   氧化还原酶 •   转移酶
病毒蛋白 •   冠状病毒蛋白 •   流感病毒蛋白 荧光蛋白 其他蛋白

搜索结果

Search Results for " k 19 "
Targets Recommended: Others

23

抑制剂 & 化合物

2

天然产物

13

重组蛋白

4

同位素标记化合物

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Cat. No. Product Name Target Signaling Pathways
T8936 Proteinase K

proteinase K for tritirachium album,Protease K,蛋白酶 K

 Others Others
Proteinase K (proteinase K for tritirachium album) 是一种非特异性丝氨酸蛋白酶，可用于蛋白消化。它在有 SDS 或尿素存在的情况下，在很大 pH 值 (4-12)、盐浓度和温度单位内均有活性。
T39581 PI3K-IN-19 hydrochloride

PI3K-IN-19 hydrochloride

 Others Others
PI3K-IN-19 hydrochloride (WO2017153220, step 5) acts as a phosphatidylinositol-3-kinase (PI3K) inhibitor.
T21254 Vonoprazan Fumarate

TAK-438,TAK 438,Vonoprazan Fumurate,TAK438,富马酸沃诺拉赞

 Proton pump Membrane transporter/Ion channel
Vonoprazan Fumarate (TAK438) 是质子泵的有效抑制剂，是口服有效的高效钾竞争性酸阻断剂，具有抗分泌活性。在 pH 为 6.5 时，它抑制猪胃微粒体中的 H+,K+-ATPase 酶活性，IC50为 19 nM。它被开发用于研究酸相关疾病，如消化性溃疡和胃食管反流病。
T14366 AZ10606120 dihydrochloride

P2X Receptor Membrane transporter/Ion channel; Neuroscience
AZ10606120 dihydrochloride 是一种可选择的、有效的、高亲和力的受体拮抗剂，在人和大鼠 P2X 7 受体上的 K D 值分别为 1.4 和 19 nM。AZ10606120 dihydrochloride 抑制肿瘤生长，具有抗血管生成活性 。AZ 10606120在与 ATP 结合位点偶联的位点结合时充当负变构调节剂。
T8388 Vonoprazan

TAK-438 (free base),沃诺拉赞

 Proton pump Membrane transporter/Ion channel
Vonoprazan (TAK-438 (free base)) 是一种质子泵抑制剂，是口服活性钾竞争性酸阻断剂，有抗分泌作用。在 pH 为 6.5 时，它抑制猪胃微粒体中的 H+,K+-ATPase 酶活性，IC50值为 19 nM。它可用于研究胃酸相关疾病。
T2404 Vonoprazan fumarate

富马酸沃诺拉赞,TAK-438

 ATPase Membrane transporter/Ion channel
Vonoprazan fumarate (TAK-438) 是一种新型 P-CAB（钾竞争性酸阻滞剂），可可逆地抑制 H+/K+、ATP 酶。
T0825 Ebselen

SPI-1005,PZ-51,依布硒,CCG-39161

 Phosphatase; Virus Protease; Calcium Channel; COX; HIV Protease Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience; Proteases/Proteasome
Ebselen (CCG-39161) 是一种谷胱甘肽过氧化物酶模拟物，是电压依赖性钙通道阻断剂。它抑制Mpro 和COVID-19病毒，是HIV-1衣壳 CTD 二聚化的抑制剂，具有抗炎、抗癌和抗氧化活性。
T72330 Antibacterial agent 19

Others Others
Antibacterial agent 19 是一种有效的抗菌剂。Antibacterial agent 19 对K. pneumoniae，(M-R)S. aureus 和 (M-R,V-R)S. aureus 具有抗菌活性, 其 MIC 值为 0.022, 0.022 和 0.045 mg/mL。
T61491 (R)-ND-336

Others Others
(R)-ND-336 is a highly potent and selective MMP-9 inhibitor, displaying a K i value of 19 nM. It also exhibits inhibitory activity against MMP-2 (K i = 127 nM) and MMP-14 (K i =119 nM). With its significant potential, (R)-ND-336 is being investigated in the field of diabetic foot ulcers (DFUs) research [1].
T40893 Estrogen receptor modulator 6

Others Others
Estrogen receptor modulator 6 (compound 3a) is a highly specific and potent agonist of the estrogen receptor (ER) β with a remarkable affinity (K i = 0.44 nM). This compound exhibits an impressive 19-fold selectivity for ERβ over ERα, as evidenced by its affinity (K i = 8.4 nM).
T79648 CDK2-IN-19

CDK Cell Cycle/Checkpoint
CDK2-IN-19 (Compound 32)为一种口服活性的选择性CDK2抑制剂（Ki：0.18 nM），在带OVCAR3肿瘤的小鼠模型中表现出显著的抗癌效果。
T79325 5-HT6 agonist 1

5-HT Receptor GPCR/G Protein; Neuroscience
5-HT6 agonist 1 (Compound 19)为一种5-HT6激动剂 (Ki: 5 nM)，展现出抗抑郁样特性并能改善认知缺陷，同时能抑制血小板聚集，具备高代谢稳定性。
T73372 GNE-2256

Others Others
GNE-2256 (molecule 19) 是一种具有口服活性的IRAK4(白介素 1 受体关联激酶 4) 抑制剂 (IRAK4Ki=1.4 nM ; IL-6IC50=190 nM)。
T79373 A3AR agonist 2

Adenosine Receptor GPCR/G Protein; Neuroscience
A3AR agonist 2 (Compound 19) 是高选择性A3AR激动剂，Ki为22.1 nM。本化合物有效促进β-arrestin2募集，展现出EC50为4.36 nM。A3AR agonist 2 主要用于研究炎症性疾病、缺血、癌症、神经性疼痛、肝脏病以及其他慢性病态。
T7492 Ripasudil free base

K-115 (free base)

 ROCK; Antibacterial Cell Cycle/Checkpoint; Cytoskeletal Signaling; Microbiology/Virology; Stem Cells
Ripasudil free base (K-115 (free base)) 是一种ROCK 特异性抑制剂，能够抑制ROCK1和ROCK2的活性，IC50值分别为 51 和 19 nM。
T61643 Vonoprazan hydrochloride

Others Others
Vonoprazan hydrochloride 是一种高效且具口服活性的质子泵抑制剂 (PPI) 和钾竞争性酸阻断剂 (potassium-competitive acid blocker, P-CAB)，展示出优秀的抗分泌活性。在 pH 为 6.5 的条件下，该化合物可抑制猪胃微粒体内 H+,K+-ATPase 的酶活性，呈现出 19 nM 的 IC50 值。Vonoprazan hydrochloride 主要应用于胃酸相关疾病的研究，包括胃食管反流病和消化性溃疡，并可用于根除幽门螺杆菌。
T9686 YH-53

Others Others
YH-53 是一种有效的3CLpro 抑制剂，对 SARS-CoV-1 3CLpro 和 SARS-CoV-2 3CLpro 的Ki 值分别为 6.3 nM、34.7 nM。YH-53 能够有效阻断 SARS-CoV-2 复制。YH-53 是一种具有独特苯并噻唑基酮的拟肽化合物。YH-53 具有用于研究新冠病毒的潜力。
T37285 1-thio-β-D-Glucose Tetraacetate

Others Others
1-thio-β-D-Glucose tetraacetate is a building block.1,2It has been used in the synthesis of aromatic glucosinolates with anti-inflammatory activity, as well as glucosylated poly(pentafluorostyrene) derivatives for coating magnetic iron oxide nanoparticles. 1.Vo, Q.V., Trenerry, C., Rochfort, S., et al.Synthesis and anti-inflammatory activity of aromatic glucosinolatesBioorg. Med. Chem.21(19)5945-5954(2013) 2.Babiuch, K., Wyrwa, R., Wagner, K., et al.Functionalized, biocompatible coating for supe...
T38385 IT-143B

Others Others
IT-143B is a bacterial metabolite that has been found in S. iakyrus.1 It inhibits the proliferation of OS-RC-2 and ACHN cancer cells (IC50s = 22 and 98 μM, respectively). |1. Li, K., Liang, Z., Chen, W., et al. Iakyricidins A-D, antiproliferative piericidin analogues bearing a carbonyl group or cyclic skeleton from Streptomyces iakyrus SCSIO NS104. J. Org. Chem. 84(19), 12626-12631 (2019).
T36999 7(S),17(S)-dihydroxy-8(E),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid

Others Others
Novel oxylipins, referred to as docosanoids, have been derived from C22polyunsaturated fatty acids 7(S),17(S)-dihydroxy-8(E),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic acid (7(S),17(S)-hydroxy DPA) is a DPA-derived analog of the 17(S)-dihydroxy series of docosanoids known as protectins. Protectin D1, a DHA-derived dihydroxy fatty acid, exhibits potent anti-inflammatory activities.1,2,3Potentially, 7(S),17(S)-hydroxy DPA demonstrates similar properties; however, its biological activity has yet to b...
T35533 6-Hydroxypyridin-3-ylboronic Acid

Others Others
6-Hydroxypyridin-3-ylboronic acid is a heterocyclic building block.1,2It has been used in the synthesis of non-nucleoside inhibitors of hepatitis C virus (HCV) RNA-dependent RNA polymerase nonstructural protein 5B (NS5B).16-Hydroxypyridin-3-ylboronic acid has also been used in the synthesis of mammalian target of rapamycin (mTOR) inhibitors.2 1.Hendricks, R.T., Spencer, S.R., Blake, J.F., et al.3-Hydroxyisoquinolines as inhibitors of HCV NS5b RNA-dependent RNA polymeraseBioorg. Med. Chem. Lett.1...
T37065 6-Chloro-2-fluoropurine

Others Others
6-Chloro-2-fluoropurine is a heterocyclic building block.1,2It has been used in the synthesis of purine nucleosides that inhibit cyclin-dependent kinases (CDKs)in vitro.16-Chloro-2-fluoropurine has also been used in the synthesis of purine nucleosides that are active against HIV-1 and hepatitis B virus (HBV)in vitro.2 1.Wilson, S.C., Atrash, B., Barlow, C., et al.Design, synthesis and biological evaluation of 6-pyridylmethylaminopurines as CDK inhibitorsBioorg. Med. Chem.19(22)6949-6965(2011) 2....
T36722 Deltorphin II (trifluoroacetate salt)

Others Others
Deltorphin II is a peptide agonist of δ2-opioid receptors.1,2It is selective for δ-opioid receptors over μ- and κ-opioid receptors in radioligand bindings assays (Kis = 0.0033, >1, and >1 μM, respectively) and induces [35S]GTPγS binding in mouse brain membrane preparations (EC50= 0.034 μM). Deltorphin II (0.12 mg/kg) decreases the infarction zone:risk zone ratio in a rat model of myocardial ischemia-reperfusion injury induced by coronary occlusion, an effect that can be reversed by the δ2-opioid...

化合物

Proteinase K
Cat.No: T8936
Synonym: proteinase K for tritirachium album,Protease K,蛋白酶 K
Target: Others
PI3K-IN-19 hydrochloride
Cat.No: T39581
Synonym: PI3K-IN-19 hydrochloride
Target: Others
Vonoprazan Fumarate
Cat.No: T21254
Synonym: TAK-438,TAK 438,Vonoprazan Fumurate,TAK438,富马酸沃诺拉赞
Target: Proton pump
AZ10606120 dihydrochloride
Cat.No: T14366
Synonym:
Target: P2X Receptor
Vonoprazan
Cat.No: T8388
Synonym: TAK-438 (free base),沃诺拉赞
Target: Proton pump
Vonoprazan fumarate
Cat.No: T2404
Synonym: 富马酸沃诺拉赞,TAK-438
Target: ATPase
Ebselen
Cat.No: T0825
Synonym: SPI-1005,PZ-51,依布硒,CCG-39161
Target: Phosphatase, Virus Protease, Calcium Channel, COX, HIV Protease
Antibacterial agent 19
Cat.No: T72330
Synonym:
Target: Others
(R)-ND-336
Cat.No: T61491
Synonym:
Target: Others
Estrogen receptor modulator 6
Cat.No: T40893
Synonym:
Target: Others
CDK2-IN-19
Cat.No: T79648
Synonym:
Target: CDK
5-HT6 agonist 1
Cat.No: T79325
Synonym:
Target: 5-HT Receptor
GNE-2256
Cat.No: T73372
Synonym:
Target: Others
A3AR agonist 2
Cat.No: T79373
Synonym:
Target: Adenosine Receptor
Ripasudil free base
Cat.No: T7492
Synonym: K-115 (free base)
Target: ROCK, Antibacterial
Vonoprazan hydrochloride
Cat.No: T61643
Synonym:
Target: Others
YH-53
Cat.No: T9686
Synonym:
Target: Others
1-thio-β-D-Glucose Tetraacetate
Cat.No: T37285
Synonym:
Target: Others
IT-143B
Cat.No: T38385
Synonym:
Target: Others
7(S),17(S)-dihydroxy-8(E),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid
Cat.No: T36999
Synonym:
Target: Others
6-Hydroxypyridin-3-ylboronic Acid
Cat.No: T35533
Synonym:
Target: Others
6-Chloro-2-fluoropurine
Cat.No: T37065
Synonym:
Target: Others
Deltorphin II (trifluoroacetate salt)
Cat.No: T36722
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
T35609 19-O-Acetylchaetoglobosin A

Others Others
19-O-Acetylchaetoglobosin A is a fungal metabolite originally isolated fromC. globosumthat has actin polymerization inhibitory and cytotoxic activities.1,2It inhibits actin polymerization in a cell-free assay when used at a concentration of 2 μM.219-O-Acetylchaetoglobosin A (3.2, 10, and 32 μg/ml) is cytotoxic to HeLa cervical cancer cells.1 1.Umeda, M., Ohtsubo, K., Saito, M., et al.Cytotoxicity of new cytochalasans from Chaetomium globosumExperientia31(4)435-438(1975) 2.Sekita, S., Yoshihira, ...
T38069 Aquastatin A

Others Others
Aquastatin A is a fungal metabolite originally isolated fromF. aquaeductuumthat has diverse biological activities.1It is active againstS. aureus(MIC = 32 μg/ml) and inhibits enoyl-acyl carrier protein reductase (Fabl; IC50= 3.2 μM) andS. aureusfatty acid synthesis (IC50= 3.5 μM).2Aquastatin A also inhibits the Na+/K+-ATPase and H+/K+-ATPase (IC50s = 7.1 and 6.2 μM, respectively), as well as protein tyrosine phosphatase 1B (PTP1B; IC50= 0.19 μM).1,3 1.Hamano, K., Kinoshita-Okami, M., Minagawa, K....

天然产物

19-O-Acetylchaetoglobosin A
Cat.No: T35609
Synonym:
Target: Others
Aquastatin A
Cat.No: T38069
Synonym:
Target: Others
Species：
SARS-CoV-2 (12)
Canine (1)
Expression System：
HEK293 Cells (7)
Baculovirus Insect Cells (5)
E. coli (1)
Tag：
C-His (10)
C-His-Avi (2)
N-His (1)
Cat. No. Product Name Species Expression System
TMPK-00687 keratin, type I cytoskeletal 19 (310-399) Protein, Canine, Recombinant (His)

KRT19,CK-19,K

Canine E. coli
Keratin 19 (K19) belongs to the keratin family of proteins, which maintains structural integrity of epithelia. In cancer, K19 is highly expressed in several types where it serves as a diagnostic marker.
TMPY-06412 SARS-CoV-2 Spike S1 Protein (T19R & G142D & W258L & K417N & L452R & T478K & D614G & P681R, His)

SARS-CoV-2 HEK293 Cells
SARS-CoV-2 Spike S1 Protein (T19R & G142D & W258L & K417N & L452R & T478K & D614G & P681R, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.56 kDa and the accession number is A0A6G7K2L4.
TMPY-06415 SARS-CoV-2 Spike S1+S2 Protein (T19R & G142D & W258L & K417N & L452R & T478K & D614G & P681R & D950N, His)

SARS-CoV-2 Baculovirus Insect Cells
SARS-CoV-2 Spike S1+S2 Protein (T19R & G142D & W258L & K417N & L452R & T478K & D614G & P681R & D950N, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 134.49 kDa and the accession number is A0A6G7K2L4.
TMPY-06413 SARS-CoV-2 Spike S1 Protein (T19R & V70F & E156G & 157-158 deletion & A222V & K417N & L452R & T478K & D614G & P681R, His)

SARS-CoV-2 HEK293 Cells
SARS-CoV-2 Spike S1 Protein (T19R & V70F & E156G & 157-158 deletion & A222V & K417N & L452R & T478K & D614G & P681R, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.28 kDa and the accession number is A0A6G7K2L4.
TMPY-06437 SARS-CoV-2 Spike S1+S2 Protein (T19R & V70F & E156G & 157-158 deletion & A222V & K417N & L452R & T478K & D614G & P681R & D950N, His)

SARS-CoV-2 Baculovirus Insect Cells
SARS-CoV-2 Spike S1+S2 Protein (T19R & V70F & E156G & 157-158 deletion & A222V & K417N & L452R & T478K & D614G & P681R & D950N, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 134.20 kDa and the accession number is A0A6G7K2L4.
TMPY-06417 SARS-CoV-2 Spike S1 Protein (T19R & E156G & 157-158 deletion & L452R & T478K & D614G & P681R, His)

SARS-CoV-2 HEK293 Cells
SARS-CoV-2 Spike S1 Protein (T19R & E156G & 157-158 deletion & L452R & T478K & D614G & P681R, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.22 kDa and the accession number is A0A6G7K2L4.
TMPY-06444 SARS-CoV-2 Spike S1 Protein (T19R & T95I & E156G & 157-158 deletion & L452R & T478K & D614G & P681R, His)

SARS-CoV-2 HEK293 Cells
SARS-CoV-2 Spike S1 Protein (T19R & T95I & E156G & 157-158 deletion & L452R & T478K & D614G & P681R, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.23 kDa and the accession number is YP_009724390.1.
TMPY-06252 SARS-CoV-2 Spike S1 Protein (T19R & G142D & E156G & 157-158 deletion & L452R & T478K & D614G & P681R, His)

SARS-CoV-2 HEK293 Cells
SARS-CoV-2 Spike S1 Protein (T19R & G142D & E156G & 157-158 deletion & L452R & T478K & D614G & P681R, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.27 kDa and the accession number is A0A6G7K2L4.
TMPY-06267 SARS-CoV-2 Spike S1 Protein (157-158 deletion & T19R & G142D & E156G & L452R & T478K & D614G & P681R, His & Avi), Biotinylated

SARS-CoV-2 HEK293 Cells
SARS-CoV-2 Spike S1 Protein (157-158 deletion & T19R & G142D & E156G & L452R & T478K & D614G & P681R, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 78.09 kDa and the accession number is A0A6G7K2L4.
TMPY-06432 SARS-CoV-2 Spike S1+S2 Protein (T19R & E156G & 157-158 deletion & L452R & T478K & D614G & P681R & D950N, His)

SARS-CoV-2 Baculovirus Insect Cells
SARS-CoV-2 Spike S1+S2 Protein (T19R & E156G & 157-158 deletion & L452R & T478K & D614G & P681R & D950N, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 134.14 kDa and the accession number is A0A6G7K2L4.
TMPY-06272 SARS-CoV-2 Spike S1+S2 Protein (T19R & G142D & E156G & 157-158 deletion & L452R & T478K & D614G & P681R & D950N, His)

SARS-CoV-2 Baculovirus Insect Cells
SARS-CoV-2 Spike S1+S2 Protein (T19R & G142D & E156G & 157-158 deletion & L452R & T478K & D614G & P681R & D950N, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 134.20 kDa and the accession number is A0A6G7K2L4.
TMPY-06288 SARS-CoV-2 Spike S1+S2 Protein (157-158 deletion & T19R & G142D & E156G & L452R & T478K & D614G & P681R & D950N, His & Avi), Biotinylated

SARS-CoV-2 Baculovirus Insect Cells
SARS-CoV-2 Spike S1+S2 Protein (157-158 deletion & T19R & G142D & E156G & L452R & T478K & D614G & P681R & D950N, His & Avi), Biotinylated is expressed in Baculovirus insect cells with His and Avi tag. The predicted molecular weight is 136.01 kDa and the accession number is A0A6G7K2L4.
TMPY-06443 SARS-CoV-2 Spike S1 Protein (T19R & T95I & G142D & Y145H & E156G & 157-158 deletion & A222V & L452R & T478K & D614G & P681R, His)

SARS-CoV-2 HEK293 Cells
SARS-CoV-2 Spike S1 Protein (T19R & T95I & G142D & Y145H & E156G & 157-158 deletion & A222V & L452R & T478K & D614G & P681R, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.29 kDa and the accession number is YP_009724390.1.

重组蛋白

keratin, type I cytoskeletal 19 (310-399) Protein, Canine, Recombinant (His)
Cat.No: TMPK-00687
Species: Canine
Expression System: E. coli
SARS-CoV-2 Spike S1 Protein (T19R & G142D & W258L & K417N & L452R & T478K & D614G & P681R, His)
Cat.No: TMPY-06412
Species: SARS-CoV-2
Expression System: HEK293 Cells
SARS-CoV-2 Spike S1+S2 Protein (T19R & G142D & W258L & K417N & L452R & T478K & D614G & P681R & D950N, His)
Cat.No: TMPY-06415
Species: SARS-CoV-2
Expression System: Baculovirus Insect Cells
SARS-CoV-2 Spike S1 Protein (T19R & V70F & E156G & 157-158 deletion & A222V & K417N & L452R & T478K & D614G & P681R, His)
Cat.No: TMPY-06413
Species: SARS-CoV-2
Expression System: HEK293 Cells
SARS-CoV-2 Spike S1+S2 Protein (T19R & V70F & E156G & 157-158 deletion & A222V & K417N & L452R & T478K & D614G & P681R & D950N, His)
Cat.No: TMPY-06437
Species: SARS-CoV-2
Expression System: Baculovirus Insect Cells
SARS-CoV-2 Spike S1 Protein (T19R & E156G & 157-158 deletion & L452R & T478K & D614G & P681R, His)
Cat.No: TMPY-06417
Species: SARS-CoV-2
Expression System: HEK293 Cells
SARS-CoV-2 Spike S1 Protein (T19R & T95I & E156G & 157-158 deletion & L452R & T478K & D614G & P681R, His)
Cat.No: TMPY-06444
Species: SARS-CoV-2
Expression System: HEK293 Cells
SARS-CoV-2 Spike S1 Protein (T19R & G142D & E156G & 157-158 deletion & L452R & T478K & D614G & P681R, His)
Cat.No: TMPY-06252
Species: SARS-CoV-2
Expression System: HEK293 Cells
SARS-CoV-2 Spike S1 Protein (157-158 deletion & T19R & G142D & E156G & L452R & T478K & D614G & P681R, His & Avi), Biotinylated
Cat.No: TMPY-06267
Species: SARS-CoV-2
Expression System: HEK293 Cells
SARS-CoV-2 Spike S1+S2 Protein (T19R & E156G & 157-158 deletion & L452R & T478K & D614G & P681R & D950N, His)
Cat.No: TMPY-06432
Species: SARS-CoV-2
Expression System: Baculovirus Insect Cells
SARS-CoV-2 Spike S1+S2 Protein (T19R & G142D & E156G & 157-158 deletion & L452R & T478K & D614G & P681R & D950N, His)
Cat.No: TMPY-06272
Species: SARS-CoV-2
Expression System: Baculovirus Insect Cells
SARS-CoV-2 Spike S1+S2 Protein (157-158 deletion & T19R & G142D & E156G & L452R & T478K & D614G & P681R & D950N, His & Avi), Biotinylated
Cat.No: TMPY-06288
Species: SARS-CoV-2
Expression System: Baculovirus Insect Cells
SARS-CoV-2 Spike S1 Protein (T19R & T95I & G142D & Y145H & E156G & 157-158 deletion & A222V & L452R & T478K & D614G & P681R, His)
Cat.No: TMPY-06443
Species: SARS-CoV-2
Expression System: HEK293 Cells
Cat. No. Product Name Target Signaling Pathways
TMIH-0601 Vonoprazan-d3

Vonoprazan-d3 是 Vonoprazan 的氘代化合物。Vonoprazan 的 CAS 号为 881681-00-1。Vonoprazan 是一种质子泵抑制剂，是口服活性钾竞争性酸阻断剂，有抗分泌作用。在 pH 为 6.5 时，它抑制猪胃微粒体中的 H+,K+-ATPase 酶活性，IC50值为 19 nM。它可用于研究胃酸相关疾病。
TMIH-0602 Vonoprazan-d4

Vonoprazan-d4 是 Vonoprazan 的氘代化合物。Vonoprazan 的 CAS 号为 881681-00-1。Vonoprazan 是一种质子泵抑制剂，是口服活性钾竞争性酸阻断剂，有抗分泌作用。在 pH 为 6.5 时，它抑制猪胃微粒体中的 H+,K+-ATPase 酶活性，IC50值为 19 nM。它可用于研究胃酸相关疾病。
T35591 Guanfacine-13C,15N3

Guanfacine-13C,15N3
Guanfacine-13C,15N3is intended for us as an internal standard for the quantification of guanfacine by GC- or LC-MS. Guanfacine is an α2-adrenergic receptor (α2-AR) agonist with Kivalues of 93, 1,380, and 3,890 nM for α2A-, α2B-, and α2C-ARs, respectively, in a radioligand binding assay.1It has EC50values of 52, 288, and 602 nM for α2A-, α2B-, and α2C-ARs, respectively, for stimulated [35S]GTPγS binding. It also binds to imidazoline receptor 1 (Ki= 19 nM in a radioligand binding assay).2Guanfacin...
T36055 Nitisinone-13C6

Nitisinone-13C6
Nitisinone-13C6is intended for use as an internal standard for the quantification of nitisinone by GC- or LC-MS. Nitisinone is an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (HPPD), which converts 4-hydroxyphenylpyruvate (HPPA) to homogentisate in the tyrosine catabolic pathway.1Nitisinone increases urinary levels of HPPA and 4-hydroxyphenyllactate (HPLA) in rats when administered at a dose of 10 mg/kg. Nitisinone (3 mg/kg) prevents the neonatal lethality of fumarylacetoacetate hydrolase (F...

同位素标记化合物

Vonoprazan-d3
Cat.No: TMIH-0601
Synonym:
Target:
Vonoprazan-d4
Cat.No: TMIH-0602
Synonym:
Target:
Guanfacine-13C,15N3
Cat.No: T35591
Synonym: Guanfacine-13C,15N3
Target:
Nitisinone-13C6
Cat.No: T36055
Synonym: Nitisinone-13C6
Target:
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