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Search Results for " k 145 "

Targets Recommended: Apoptosis S1P Receptor

3

抑制剂 & 化合物

1

天然产物

7

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
TQ0138	K145 hydrochloride K145盐酸盐	Apoptosis; S1P Receptor	Apoptosis; GPCR/G Protein
	K145 hydrochloride 是选择性的，底物竞争性的和口服有效的SphK2抑制剂，IC50为 4.3 µM，Ki 为 6.4 µM。它可诱导细胞凋亡，显示出强大的抗肿瘤活性。
T11739	K145	Others	Others
	K145 is inactive against SphK1 and other protein kinases. K145 induces cell apoptosis and has potently antitumor activity. K145 is a selective, substrate-competitive and orally active SphK2 inhibitor with an IC50 of 4.3 µM and a Ki of 6.4 µM.
T35955	PAR2 (1-6) amide (human) (trifluoroacetate salt) PAR2 (1-6) amide (human) (trifluoroacetate salt)
	PAR2 (1-6) amide is a synthetic peptide agonist of proteinase-activated receptor 2 (PAR2) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of human PAR2 and residues 37-42 of the full-length sequence.1It binds to NCTC 2544 cells expressing human PAR2 (Ki= 9.64 μM in a radioligand binding assay) and induces calcium mobilization in the same cells (EC50= 0.075 μM).2PAR2 (1-6) amide (100 μM) reduces colony formation of A549 lung cancer cells.1It induces superoxide prod...

化合物

K145 hydrochloride

Cat.No: TQ0138

Synonym: K145盐酸盐

Target: Apoptosis, S1P Receptor

Cat.No: T11739

Target: Others

PAR2 (1-6) amide (human) (trifluoroacetate salt)

Cat.No: T35955

Synonym: PAR2 (1-6) amide (human) (trifluoroacetate salt)

Cat. No.	Product Name	Target	Signaling Pathways
T36329	Terpendole I	Others	Others
	Terpendole I is a fungal metabolite that has been found in A. yamanashiensis.1 It is a weak inhibitor of acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 145 μM) and is active against the bacteria B. cereus and B. subtilis (MICs = 100 μg/ml for both) but not S. aureus, P. aeruginosa, or K. pneumoniae (MICs = >200 μg/ml for all) or the fungus C. albicans (MIC = 200 μg/ml).1,2 It is cytotoxic to HeLa cells with an IC50 value of 52.6 μM.3 \|1. Tomoda, H., Tabata, N., Yang, D.-J., et al. Ter...

天然产物

Cat.No: T36329

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04690	Influenza A H3N2 (A/Netherlands/178/1995 (RG145K)) Hemagglutinin/HA Protein (His) Harvey rat sarcoma viral oncogene homolog	H3N2	Baculovirus Insect Cells
	Influenza A H3N2 (A/Netherlands/178/1995 (RG145K)) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.3 kDa and the accession number is I6V5M4.
TMPY-04603	Influenza A H3N2 (A/Netherlands/178/1995 (RG145K)) Hemagglutinin/HA1 Protein (His) Harvey rat sarcoma viral oncogene homolog	H3N2	HEK293 Cells
	Influenza A H3N2 (A/Netherlands/178/1995 (RG145K)) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38 kDa and the accession number is I6V5M4.
TMPY-06270	SARS-CoV-2 Spike S1+S2 Protein (145-146 deletion & E484K & D614G, His)	SARS-CoV-2	Baculovirus Insect Cells
	SARS-CoV-2 Spike S1+S2 Protein (145-146 deletion & E484K & D614G, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 134.03 kDa and the accession number is A0A6G7K2L4.
TMPY-06205	SARS-CoV-2 Spike S1 Protein (H49Y & 145-146 deletion & E484K & D614G, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike S1 Protein (H49Y & 145-146 deletion & E484K & D614G, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.5 kDa and the accession number is A0A6G7K2L4.
TMPY-06421	SARS-CoV-2 Spike S1 Protein (T95I & Y144S & Y145N & R346K & E484K & N501Y & D614G & P681H, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike S1 Protein (T95I & Y144S & Y145N & R346K & E484K & N501Y & D614G & P681H, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.36 kDa and the accession number is A0A6G7K2L4.
TMPY-06433	SARS-CoV-2 Spike S1 Protein (P9L & C136F & 144-145 deletion & R190S & D215G & Y449H & E484K & N501Y & D614G & H655Y & N679K, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike S1 Protein (P9L & C136F & 144-145 deletion & R190S & D215G & Y449H & E484K & N501Y & D614G & H655Y & N679K, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.06 kDa and the accession number is A0A6G7K2L4.
TMPY-06443	SARS-CoV-2 Spike S1 Protein (T19R & T95I & G142D & Y145H & E156G & 157-158 deletion & A222V & L452R & T478K & D614G & P681R, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike S1 Protein (T19R & T95I & G142D & Y145H & E156G & 157-158 deletion & A222V & L452R & T478K & D614G & P681R, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.29 kDa and the accession number is YP_009724390.1.

重组蛋白

Influenza A H3N2 (A/Netherlands/178/1995 (RG145K)) Hemagglutinin/HA Protein (His)

Cat.No: TMPY-04690

Species: H3N2

Expression System: Baculovirus Insect Cells

Influenza A H3N2 (A/Netherlands/178/1995 (RG145K)) Hemagglutinin/HA1 Protein (His)

Cat.No: TMPY-04603

Species: H3N2

Expression System: HEK293 Cells

SARS-CoV-2 Spike S1+S2 Protein (145-146 deletion & E484K & D614G, His)

Cat.No: TMPY-06270

Species: SARS-CoV-2

Expression System: Baculovirus Insect Cells

SARS-CoV-2 Spike S1 Protein (H49Y & 145-146 deletion & E484K & D614G, His)

Cat.No: TMPY-06205

Species: SARS-CoV-2

Expression System: HEK293 Cells

SARS-CoV-2 Spike S1 Protein (T95I & Y144S & Y145N & R346K & E484K & N501Y & D614G & P681H, His)

Cat.No: TMPY-06421

Species: SARS-CoV-2

Expression System: HEK293 Cells

SARS-CoV-2 Spike S1 Protein (P9L & C136F & 144-145 deletion & R190S & D215G & Y449H & E484K & N501Y & D614G & H655Y & N679K, His)

Cat.No: TMPY-06433

Species: SARS-CoV-2

Expression System: HEK293 Cells

SARS-CoV-2 Spike S1 Protein (T19R & T95I & G142D & Y145H & E156G & 157-158 deletion & A222V & L452R & T478K & D614G & P681R, His)

Cat.No: TMPY-06443

Species: SARS-CoV-2

Expression System: HEK293 Cells

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