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Targets Recommended: Retinoid Receptor RAR/RXR 

1158

抑制剂 & 化合物

173

天然产物

4

化合物库

7

TargetMol 试剂盒

294

重组蛋白

27

同位素标记化合物

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Cat. No. Product Name
L1300 PI3K/Akt/mTOR 化合物库

420 compounds
420 种与PI3K/Akt/mTOR 相关的生物活性小分子化合物的特有集合,用于PI3K/Akt/mTOR 相关研究以及高通量、高内涵筛选;
L3510 甲基化化合物库

128 compounds
128 种甲基化相关的化合物,可以用于高通量和高内涵筛选;
L7300 钾通道分子库

152 compounds
152 种钾通道相关化合物的独特集合,可用于高通量筛选和高内涵筛选;
L8710 铜死亡化合物库

400 compounds
TargetMol 铜死亡化合物库集合了 400 种与铜死亡相关的化合物,可以用于铜死亡机制及相关疾病研究

化合物库

PI3K/Akt/mTOR 化合物库
Cat.No: L1300
Compounds: 420
甲基化化合物库
Cat.No: L3510
Compounds: 128
钾通道分子库
Cat.No: L7300
Compounds: 152
铜死亡化合物库
Cat.No: L8710
Compounds: 400
Cat. No. Product Name Form Specificity Of Inhibition
C0090 Mag Beads Streptavidin (1 μm)

链霉亲和素磁珠 (1 μm)

Suspension in bottle 免疫检测、分离蛋白;分离核酸、制备核酸探针;DNA-蛋白质相互作用研究;细胞分选与激活
C0095 Magrose Beads Streptavidin (Ultra-suspension)

琼脂糖链霉亲和素磁珠

Suspension in bottle 免疫检测、分离蛋白;分离核酸、制备核酸探针;DNA-蛋白质相互作用研究;细胞分选与激活
C0089 Mag Beads Streptavidin (300 nm)

链霉亲和素磁珠 (300 nm)

Suspension in bottle 免疫检测、分离蛋白;分离核酸、制备核酸探针;DNA-蛋白质相互作用研究;细胞分选与激活
C0093 Mag Beads Streptavidin (3 μm)

链霉亲和素磁珠 (3 μm)

Suspension in bottle 免疫检测、分离蛋白;分离核酸、制备核酸探针;DNA-蛋白质相互作用研究;细胞分选与激活
C0094 Mag Beads Streptavidin (5 μm)

链霉亲和素磁珠 (5 μm)

Suspension in bottle 免疫检测、分离蛋白;分离核酸、制备核酸探针;DNA-蛋白质相互作用研究;细胞分选与激活
C0091 Mag Beads Streptavidin (2 μm)

链霉亲和素磁珠 (2 μm)

Suspension in bottle 免疫检测、分离蛋白;分离核酸、制备核酸探针;DNA-蛋白质相互作用研究;细胞分选与激活
C0092 Mag Beads Streptavidin (2.8 μm)

链霉亲和素磁珠 (2.8 μm)

Suspension in bottle 免疫检测、分离蛋白;分离核酸、制备核酸探针;DNA-蛋白质相互作用研究;细胞分选与激活

TargetMol 试剂盒

链霉亲和素磁珠 (1 μm)
Cat.No: C0090
琼脂糖链霉亲和素磁珠
Cat.No: C0095
链霉亲和素磁珠 (300 nm)
Cat.No: C0089
链霉亲和素磁珠 (3 μm)
Cat.No: C0093
链霉亲和素磁珠 (5 μm)
Cat.No: C0094
链霉亲和素磁珠 (2 μm)
Cat.No: C0091
链霉亲和素磁珠 (2.8 μm)
Cat.No: C0092
Cat. No. Product Name Target Signaling Pathways
T24240 K-8012

K8012,K 8012

Retinoid Receptor; RAR/RXR  Metabolism
K-8012 是 N 末端截短的 RXRα 的调节剂,并以 RXRα 依赖性方式提高抗癌活性。
T11742 K-7174

IL Receptor; TNF Apoptosis; Immunology/Inflammation
K-7174 是一种新型细胞粘附抑制剂, 抑制由 IL-1β 或 TNF-α 诱导的血管细胞粘附分子 1 (VCAM-1) 的表达。
T15639 K-756

PARP; Wnt/beta-catenin Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; Stem Cells
K-756 是一种直接的 tankyrase(TNKS) 选择性抑制剂,对 TNKS1和 TNKS2的 ADP-核糖基化活性有抑制作用,IC50分别为 31 和 36 nM。
T8936 Proteinase K

proteinase K for tritirachium album,Protease K,蛋白酶 K

Others Others
Proteinase K (proteinase K for tritirachium album) 是一种非特异性丝氨酸蛋白酶,可用于蛋白消化。它在有 SDS 或尿素存在的情况下,在很大 pH 值 (4-12)、盐浓度和温度单位内均有活性。
T11742L K-7174 dihydrochloride

K7174 2HCl,K-7174 2HCl,K 7174 2HCl

Proteasome Proteases/Proteasome; Ubiquitination
K-7174 dihydrochloride 是具有口服活性的 proteasome 和 GATA 抑制剂,抑制白细胞粘附和炎症因子表达,抑制神经元变性,诱导细胞凋亡。K-7174 dihydrochloride 具有抗肿瘤活性,可用于研究神经精神系统性红斑狼疮和认知功能障碍。
T9954 K-975

Others Others
K-975是一种高选择性的具有口服活性的TEAD 抑制剂,可有效抑制TEAD 和YAP1/TAZ 之间的蛋白质-蛋白质相互作用。
T11733 K-604 dihydrochloride

Acyltransferase Metabolism
K-604 dihydrochloride 是酰基辅酶 A:胆固醇酰基转移酶 1 的选择性抑制剂,IC50为 0.45±0.06 μM。
T27706 K-111

BM 170744,K111,K 111,BM170744,BM-170744

PPAR DNA Damage/DNA Repair; Metabolism
K-111 (BM-170744) 是一种可口服的过氧化物酶体增殖物激活受体 (PPAR)-α 激动剂和胰岛素增强剂,可用于研究肥胖型糖尿病和代谢综合征。
T11734 K-80003

TX-803

Akt; RAR/RXR  Cytoskeletal Signaling; Metabolism; PI3K/Akt/mTOR signaling
K-80003(TX-803) 是一种有效的类视黄醇 X 受体α调节剂,对 tRXRα 依赖性的 Akt 激活和肿瘤细胞生长有抑制作用。
T6777 Bay K 8644

(±)-BAY-K-8644,SQ 28,873

Calcium Channel Membrane transporter/Ion channel; Metabolism
Bay K 8644 (SQ 28,873)是一种二氢吡啶化合物,是一种选择性的 L 型 Ca2+ 通道激活剂,IC50 为 17.3 nM。它通过增加通道的开放时间来增加通过肌膜 Ca2+通道的 Ca2+流入。
TQ0145 (R)-(+)-Bay-K-8644

(R)-(+)-Bay K 8644

Calcium Channel; PPAR DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism
(R)-(+)-Bay-K-8644 是一种 Ca2+ 通道抑制剂,也能抑制 Ba2+电流 (IBa),诱导猫的中枢性呼吸抑制,通过竞争性拮抗血栓素 A2-前列腺素 H2 受体抑制血小板活化。
TP2009L K 41498 aceate

CRFR GPCR/G Protein
K41498 acetate 是 antisauvagine-30 的类似物,可抑制 suvagine 刺激的 cAMP 在表达 hCRF2α 和 hCRF2β 的细胞中的积累。 K41498 acetate 是一种有效且高度选择性的 CRF2 受体拮抗剂,对人 CRF2α、CRF2β 和 CRF1 受体的 Ki 值分别为 0.66 nM、0.62 nM 和 425 nM。
TQ0144 (S)-(-)-Bay-K-8644

(S)-(-)-Bay K 8644

Calcium Channel Membrane transporter/Ion channel; Metabolism
(S)-(-)-Bay-K-8644 ((S)-(-)-Bay K 8644) 是 L 型 Ca2+ 通道的激动剂,可激活 Ba2+ 电流,其EC50 为 32 nM。
T29087 VA-K-14 hydrochloride

VAK14 Hydrochloride,VA K 14 HCl,VA-K-14 HCl,VAK14 HCl

TSH Receptor GPCR/G Protein
VA-K-14 hydrochloride(VAK14 HCl)是一种选择性促甲状腺激素受体 (TSHR) 拮抗剂 (IC50= 12.3 μM),对GD患者血清和单克隆刺激TSHR抗体对TSHR的刺激有抑制作用,可消除 TSHR 信号传导。
T5469 K-Ras-IN-1

Raf; Ras GPCR/G Protein; MAPK
K-Ras-IN-1 是K-Ras 抑制剂。K-Ras-IN-1 能与 K-Ras (WT)、K-Ras (G12D)、K-Ras (G12V) 和 H-Ras 结合。它对胰腺癌、结肠癌和肺癌的具潜在的研究价值。
T11738 K-Ras G12C-IN-4

Ras GPCR/G Protein; MAPK
K-Ras G12C-IN-4 是一种 KRAS G12C 共价抑制剂。
T4618 BGG463

K 0859

Bcr-Abl; CDK Angiogenesis; Cell Cycle/Checkpoint; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
BGG463 (K 0859) 是一种具有口服活性的 II 型 CDK2的抑制剂,可抑制 c-ABL-T334I、BCR-ABL 和 BCR-ABL-T315I 变体,IC50分别为 0.25 μM、0.09 μM 和 0.590 μM。
T6556 K-Ras(G12C) inhibitor 9

Raf MAPK
K-Ras(G12C) inhibitor 9 是致癌 K-Ras(G12C) 的变构抑制剂。
T3725 K-Ras(G12C) Inhibitor 6

Raf MAPK
KRas(G12C) inhibitor 6 是一种变构的,选择性的 K-Ras(G12C)抑制剂。
T1914 K02288

K 02288

ALK; TGF-beta/Smad Angiogenesis; Stem Cells; Tyrosine Kinase/Adaptors
K 02288是骨形态发生蛋白 (BMP) I 型受体抑制剂,能够抑制 ALK1 (IC50:1.8nM)、ALK2 (IC50:1.1nM)、ALK6 (IC50:6.4nM)。对 ALK3 和 ALK6 的抑制稍弱,IC50在 5-34 nM 之间。
T6555 K-Ras(G12C) inhibitor 12

Apoptosis; Raf; Ras Apoptosis; GPCR/G Protein; MAPK
K-Ras(G12C) inhibitor 12是一种K-Ras(G12C)抑制剂,作用于H1792细胞,EC50为0.32 μM。
T8659 K-Ras-PDEδ-IN-1

PDE Metabolism
K-Ras-PDEδ-IN-1 是新型的 K-Ras-PDEδ 抑制剂,它能够以低纳摩尔Kd8 nM 与 PDEδ 的法尼基结合袋竞争性结合。
T24239 K201

K-201,JTV 519,JTV-519,K 201

Calcium Channel Membrane transporter/Ion channel; Metabolism
K201 (JTV-519) 是一种 Ca2+ 依赖性阻滞剂,通过稳定兰尼碱受体来防止缺血性心脏和骨骼肌 (SkM) 中的肌质网异常 Ca(2+) 泄漏。
T27704 K00135

K-00135,Imidazol[1,2-b]pyridazine 1,K 00135,IMIDAZOPYRIDAZIN 1

Pim Chromatin/Epigenetic; JAK/STAT signaling
K00135 (IMIDAZOPYRIDAZIN 1) 是 Pim 激酶的选择性抑制剂,可用于胃癌和抗白血病治疗的研究。
TQ0138 K145 hydrochloride

K145盐酸盐

Apoptosis; S1P Receptor Apoptosis; GPCR/G Protein
K145 hydrochloride 是选择性的,底物竞争性的和口服有效的SphK2抑制剂,IC50为 4.3 µM,Ki 为 6.4 µM。它可诱导细胞凋亡,显示出强大的抗肿瘤活性。
T15641 K777

APC-3316

P450; Cysteine Protease; CCR Immunology/Inflammation; Metabolism; Microbiology/Virology; Proteases/Proteasome
K777 是有效的,具有口服活性的,不可逆的半胱氨酸蛋白酶 (cysteine protease) 抑制剂。K777是有效的 CYP3A4 抑制剂(IC50= 60 nM)。K777也是选择性的 CCR4 拮抗剂,显示出强的趋化性抑制作用。K777 对 Cruzain(克鲁斯锥虫的主要半胱氨酸蛋白酶)和组织蛋白酶 B 和 L 具有不可逆的抑制作用。K777 通过靶向组织蛋白酶介导的细胞进入,显示出广谱的抗病毒作用。K777 抑制 EBOV 和 SARS-CoV 病毒的进入,IC50 值分别为 0.87 nM 和 0.68 nM。
T6866 AUZ 454

K03861

CDK Cell Cycle/Checkpoint
AUZ 454 (K03861) 是一种 II 型 CDK2 抑制剂,Kd 值是 8.2 nM。它对 CDK2(WT)、CDK2(C118L)、CDK2(A144C) 和 CDK2(C118L/A144C) 的 Kd 分别为 50 nM、18.6 nM、15.4 nM 和 9.7 nM。
T3120 K858 (Racemic)

K858 Racemic,K858

Apoptosis; Kinesin Apoptosis; Cytoskeletal Signaling
K858 Racemic (K858) 是一种选择性有丝分裂驱动蛋白 Eg5 抑制剂,以 ATP 非竞争性方式起作用,IC50值为 1.3 μM。
TP1682L Abz-FR-K(Dnp)-P-OH acetate

Abz-FR-K(Dnp)-P-OH acetate (500799-61-1 free base)

Others Others
Abz-FR-K(Dnp)-P-OH acetate(500799-61-1 free base) 是一种出色的血管紧张素 I 转换酶 (ACE) 底物,Km 值为 4.0 μM,kcat 值为 210s-1。
T27710 K6PC-5

K6PC5,K6PC 5

S1P Receptor GPCR/G Protein
K6PC-5 is a ceramide derivative that acts as an activator of sphingosine kinase 1 (SPHK1), inducing a swift and temporary rise in intracellular calcium levels. With its potential applications in skin diseases associated with abnormal keratinocyte function, as well as in studies on neurodegeneration and virus infection, K6PC-5 presents a promising compound for research purposes.
T33581 Nafetolol

K 5407,K-5407

Others Others
Nafetolol (K 5407) 是一种生化试剂,可用于合成其他化合物。
T125462 Gnetifolin K

GnetifolinK

Gnetifolin K (GnetifolinK) 是一种来自 Gnetum parvifolium 的新型二苯乙烯二葡萄糖苷,具有潜在的神经保护活性,可用于研究DNA损伤。
T36100 K-TMZ

Others Others
K-TMZ is a DNA alkylating agent. It increases the concentration of O6-methylated deoxyguanosine in U87 glioblastoma multiforme (GBM) cells in a concentration-dependent manner. K-TMZ reduces cell viability of GBM cell lines lacking (IC50s = 18-44 μM) or expressing O6-methylguanine DNA methyltransferase (MGMT; IC50s = 115-240 μM). K-TMZ can cross the blood-brain barrier and increases survival in a Br23c mouse xenograft model of GBM when administered at a dose of 14.9 mg/kg.
T9418 NEUROPEPTIDE K

Others Others
NEUROPEPTIDE K 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T9418,CAS号为 106441-70-7。
T69760 TT-10

TAZ-K

YAP Stem Cells
TT-10 (TAZ-K) 作为YES相关蛋白(YAP)-转录增强因子结构域(TEAD)活性的激活剂,适用于心肌细胞丢失伴随心脏病研究。
T70949 K-8986

Others Others
K-8986 is a novel h1-receptor antagonist
T27832 Lifibrol

U 83860,K-12148,K-12.148,U-83860,K12148

Lipid Metabolism
Lifibrol (U-83860) 是一种胆固醇合成抑制剂。Lifibrol 具有抗胆固醇和降血脂的作用,可促进高胆固醇血症和混合型高脂血症患者体内低密度脂蛋白载脂蛋白 B-100 的转化。
T40537 Ibuprofen Impurity K

Others Others
Ibuprofen Impurity K is a compound that serves as an impurity in Ibuprofen. Ibuprofen itself is an anti-inflammatory inhibitor specifically designed to target COX-1 and COX-2. It exhibits inhibitory activity with IC50 values of 13 μM and 370 μM for COX-1 and COX-2, respectively.
T8882 Vodobatinib

K-0706

Bcr-Abl Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
Vodobatinib (K-0706) 是第三代具有口服活性的Bcr-Abl1酪氨酸激酶抑制剂,IC50=7 nM,对大多数 BCR-ABL1 点突变体具有活性,但对 BCR-ABL1T315I 无活性。它可用于研究慢性粒细胞白血病 (CML)。
T25682 Leucinostatin K

Leucinostatin-K

Others Others
Leucinostatin K is a new peptide antibiotic from Paecilomyces lilacinus.
T32354 K 8409

K8409,K-8409

Others Others
K 8409 is a bioactive chemical.
T32349 K 2604

K-2604,K2604

Others Others
K 2604 is a bioactive chemical.
T32352 K 486

K486,K-486,K 486, CARBANILIC ACID

Others Others
K 486 is a bioactive chemical.
T22886 K 579

Others Others
K 579 is a dipeptidyl peptidase IV inhibitor.
T24215 JS-K

JSK,JS K

Others Others
JS-K is a Nitric oxide donor. It has antiproliferative activity.
T21950 K 00546

Others Others
K00546 是一种有效的细胞周期蛋白依赖性激酶CDK1和CDK2抑制剂,对CDK1/cyclin B 和CDK2/cyclin A 的IC50分别为 0.6 nM 和 0.5 nM。K00546 也是一种有效的 CDC2 样激酶 1 (CLK1) 和CLK3抑制剂,IC50分别为 8.9 nM 和 29.2 nM。
T32345 K 12425

K-12425,K12425

Others Others
K 12425 is a bioactive chemical.
T25564 K-13

K-13 (Ace inhib)

Others Others
K-13 is used as an ACE inhibitor produced by Micromonospora halophytics subsp. exilisia K-13.
T32351 K 309

Others Others
K 309 is a bioactive chemical.
T32350 K 308

K-308,K308

Others Others
K 308 is a bioactive chemical.

化合物

K-8012
Cat.No: T24240
Synonym: K8012,K 8012
Target: Retinoid Receptor, RAR/RXR 
K-7174
Cat.No: T11742
Synonym:
Target: IL Receptor, TNF
K-756
Cat.No: T15639
Synonym:
Target: PARP, Wnt/beta-catenin
Proteinase K
Cat.No: T8936
Synonym: proteinase K for tritirachium album,Protease K,蛋白酶 K
Target: Others
K-7174 dihydrochloride
Cat.No: T11742L
Synonym: K7174 2HCl,K-7174 2HCl,K 7174 2HCl
Target: Proteasome
K-975
Cat.No: T9954
Synonym:
Target: Others
K-604 dihydrochloride
Cat.No: T11733
Synonym:
Target: Acyltransferase
K-111
Cat.No: T27706
Synonym: BM 170744,K111,K 111,BM170744,BM-170744
Target: PPAR
K-80003
Cat.No: T11734
Synonym: TX-803
Target: Akt, RAR/RXR 
Bay K 8644
Cat.No: T6777
Synonym: (±)-BAY-K-8644,SQ 28,873
Target: Calcium Channel
(R)-(+)-Bay-K-8644
Cat.No: TQ0145
Synonym: (R)-(+)-Bay K 8644
Target: Calcium Channel, PPAR
K 41498 aceate
Cat.No: TP2009L
Synonym:
Target: CRFR
(S)-(-)-Bay-K-8644
Cat.No: TQ0144
Synonym: (S)-(-)-Bay K 8644
Target: Calcium Channel
VA-K-14 hydrochloride
Cat.No: T29087
Synonym: VAK14 Hydrochloride,VA K 14 HCl,VA-K-14 HCl,VAK14 HCl
Target: TSH Receptor
K-Ras-IN-1
Cat.No: T5469
Synonym:
Target: Raf, Ras
K-Ras G12C-IN-4
Cat.No: T11738
Synonym:
Target: Ras
BGG463
Cat.No: T4618
Synonym: K 0859
Target: Bcr-Abl, CDK
K-Ras(G12C) inhibitor 9
Cat.No: T6556
Synonym:
Target: Raf
K-Ras(G12C) Inhibitor 6
Cat.No: T3725
Synonym:
Target: Raf
K02288
Cat.No: T1914
Synonym: K 02288
Target: ALK, TGF-beta/Smad
K-Ras(G12C) inhibitor 12
Cat.No: T6555
Synonym:
Target: Apoptosis, Raf, Ras
K-Ras-PDEδ-IN-1
Cat.No: T8659
Synonym:
Target: PDE
K201
Cat.No: T24239
Synonym: K-201,JTV 519,JTV-519,K 201
Target: Calcium Channel
K00135
Cat.No: T27704
Synonym: K-00135,Imidazol[1,2-b]pyridazine 1,K 00135,IMIDAZOPYRIDAZIN 1
Target: Pim
K145 hydrochloride
Cat.No: TQ0138
Synonym: K145盐酸盐
Target: Apoptosis, S1P Receptor
K777
Cat.No: T15641
Synonym: APC-3316
Target: P450, Cysteine Protease, CCR
AUZ 454
Cat.No: T6866
Synonym: K03861
Target: CDK
K858 (Racemic)
Cat.No: T3120
Synonym: K858 Racemic,K858
Target: Apoptosis, Kinesin
Abz-FR-K(Dnp)-P-OH acetate
Cat.No: TP1682L
Synonym: Abz-FR-K(Dnp)-P-OH acetate (500799-61-1 free base)
Target: Others
K6PC-5
Cat.No: T27710
Synonym: K6PC5,K6PC 5
Target: S1P Receptor
Nafetolol
Cat.No: T33581
Synonym: K 5407,K-5407
Target: Others
Gnetifolin K
Cat.No: T125462
Synonym: GnetifolinK
Target:
K-TMZ
Cat.No: T36100
Synonym:
Target: Others
NEUROPEPTIDE K
Cat.No: T9418
Synonym:
Target: Others
TT-10
Cat.No: T69760
Synonym: TAZ-K
Target: YAP
K-8986
Cat.No: T70949
Synonym:
Target: Others
Lifibrol
Cat.No: T27832
Synonym: U 83860,K-12148,K-12.148,U-83860,K12148
Target: Lipid
Ibuprofen Impurity K
Cat.No: T40537
Synonym:
Target: Others
Vodobatinib
Cat.No: T8882
Synonym: K-0706
Target: Bcr-Abl
Leucinostatin K
Cat.No: T25682
Synonym: Leucinostatin-K
Target: Others
K 8409
Cat.No: T32354
Synonym: K8409,K-8409
Target: Others
K 2604
Cat.No: T32349
Synonym: K-2604,K2604
Target: Others
K 486
Cat.No: T32352
Synonym: K486,K-486,K 486, CARBANILIC ACID
Target: Others
K 579
Cat.No: T22886
Synonym:
Target: Others
JS-K
Cat.No: T24215
Synonym: JSK,JS K
Target: Others
K 00546
Cat.No: T21950
Synonym:
Target: Others
K 12425
Cat.No: T32345
Synonym: K-12425,K12425
Target: Others
K-13
Cat.No: T25564
Synonym: K-13 (Ace inhib)
Target: Others
K 309
Cat.No: T32351
Synonym:
Target: Others
K 308
Cat.No: T32350
Synonym: K-308,K308
Target: Others
Cat. No. Product Name Target Signaling Pathways
T5S2309 Hosenkoside K

凤仙萜四醇苷K,(+)-Hosenkoside K

Others Others
Hosenkoside K 是一种糖苷,分离自凤仙花种子。
T8200 Ginkgolide K

银杏内酯 K,银杏内酯K

AMPK; Autophagy Autophagy; Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
Ginkgolide K 是从银杏中分离得到的一种二萜类天然产物,有神经保护活性,可通过 AMPK/mTOR/ULK1信号通路诱导保护性自噬。
T19603 Vitamin K

Kephton,维生素K,Vitamin K1(20)

Endogenous Metabolite Metabolism
Vitamin K (Kephton) 具有凝血作用,对凝血因子、基质-Gla 蛋白和骨钙素很重要。
T3811 Ginsenoside C-K

20(S)-人参皂苷 C-K,Ginsenoside compound K,Ginsenoside K,人参皂苷 C-K

P450; cell cycle arrest; COX; NO Synthase Cell Cycle/Checkpoint; Immunology/Inflammation; Metabolism; Neuroscience
Ginsenoside C-K (Ginsenoside K) 是 Ginsenoside Rb1 的细菌代谢物,可通过抑制诱生型一氧化氮合酶和COX-2来发挥抗炎作用。它在人肝微粒体中抑制CYP2C9和CYP2A6活性,IC50分别为 32.0±3.6 和 63.6±4.2 μM。
T0449 Menadione

维生素K3,Vitamin K3,甲萘醌

Thrombin; Endogenous Metabolite Metabolism; Proteases/Proteasome
Menadione (Vitamin K3) 是合成的萘醌,能够在体内转化成活性维生素 K2。
T2570 Vitamin K4

维生素K4,维生素 K4,Kapilin,Menadiol Diacetate,acetomenaphthone

Apoptosis; Endogenous Metabolite Apoptosis; Metabolism
Vitamin K4 (Menadiol Diacetate) 是一种维生素药物,用于治疗因缺乏 VK4 引起的凝血障碍。
TN5268 Yadanzioside K

Others Others
Yadanzioside K is a natural product from Brucea javanica.
TN2266 Terrestrosin K

Others Others
Terrestrosin K is a natural product
TN1843 Kushenol K

PDE; HSV Metabolism; Microbiology/Virology
Kushenol K is a potent and Selective Inhibitor of cGMP Phosphodiesterase 5, it also has inhibitory effects on diacylglycerol acyltransferase (DGAT). Kushenol K shows weak antiviral activity against Herpes simplex virus types I and II.
TN1388 Angelol K

Others Others
Angelol K shows significant activity on human platelet aggregation.
TN1945 Momordicoside K

Others Others
Momordicoside K has antidiabetic activity.
T75675 Nepasaikosaponin K

Antiviral Immunology/Inflammation
Nepasaikosaponin K 是一种从柴胡根中分离出来小分子化合物,具有抗流感和抗病毒活性,可用于研究病毒感染。
TN4971 Sculponeatin K

Others Others
Sculponeatin K是一种天然产物,属于唇形科香茶菜属,其产品编号为 TN4971,CAS号为 477529-70-7。Sculponeatin K可用作对照参考。
TN5664 Epimedonin K

Epimedonin K 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5664,CAS号为 2222285-85-8。
TN6589 Grossamide K

Grossamide K exerts a particularly strong anti-melanogenic activity on the cells without high cell toxicity.
TN5465 Derrisisoflavone K

Derrisisoflavone K 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5465,CAS号为 2172624-68-7。
TN3646 Chlorovaltrate K

Others Others
Chlorovaltrate K shows moderate cytotoxicity against lung adenocarcinoma (A 549), metastatic prostate cancer (PC-3M), colon cancer (HCT-8) and hepatoma (Bel 7402) cell lines with IC50 values of 0.89-9.76 uM.
TN4942 Sanggenone K

Others Others
Sanggenone K 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN4942,CAS号为 86450-77-3。
TN4481 Macrocarpal K

Others Others
Macrocarpal K 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN4481,CAS号为 218290-59-6。
T15638 K-252c

PKC Chromatin/Epigenetic; Cytoskeletal Signaling
K-252c is a staurosporine analog isolated from Nocardiopsis sp. and is a cell-permeable PKC inhibitor (IC50: 2.45 μM). K-252c also inhibits β-lactamase, chymotrypsin, and malate dehydrogenase. K-252c causes apoptosis in human chronic myelogenous leukemia cancer cells.
TN4362 k-Strophanthoside

Others Others
k-Strophanthoside 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN4362,CAS号为 33279-57-1。
TN4805 Platycoside K

Others Others
Platycoside K 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN4805,CAS号为 899447-64-4。
TN4589 Mulberrofuran K

Others Others
Mulberrofuran K shows potent anti-oxidation activities.
TN3971 Epimedin K

Others Others
Epimedin K is a natural product from Epimedium koreanum NAKAI (Berberidaceae).
TN5846 Mumeose K

Mumeose K 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5846,CAS号为 2132384-01-9。
T15637 K-252b

PKC Chromatin/Epigenetic; Cytoskeletal Signaling
K-252b is an indolocarbazole isolated from the actinomycete Nocardiopsis and is a PKC inhibitor. K-252b can be used to inhibit extracellular kinases of cells in culture because it can’t pass through the cell membrane freely.
TN3105 5-Dehydroxyparatocarpin K

Others Others
5-Dehydroxyparatocarpin K是一种天然产物,属于豆科补骨脂属,其产品编号为 TN3105,CAS号为 124858-37-3。5-Dehydroxyparatocarpin K可用作对照参考。
T25563 K 41

K-41,K41,Antibiotic K-41A,37454 RP,Antibiotic A 32887

Others Others
K 41 is a polycyclic polyether antibiotic from Streptomyces hygroscopicus.
T15636 K-252a

Antibiotic K 252a,Antibiotic SF 2370,SF2370

Others Others
K-252a is a staurosporine analog isolated from Nocardiopsis sp. soil fungi. K-252a inhibits protein kinase (IC50: 470 nM, 140 nM, 270 nM, and 1.7 nM for PKC, PKA, Ca2+/calmodulin-dependent kinase type II, and phosphorylase kinase, respectively).
TN4103 Ganoderic acid K

Ganoderic acid K is an angiotensin-converting enzyme inhibitor. It has anti-tumor, and anti-inflammatory activities.
TN1631 Eupalinolide K

[3AR-[3AR*,4R*(E),6E,9S*,10E,11AR*]]-4-羟基-2-甲基-2-丁烯酸 2,3,3A,4,5,8,9,11A-八氢-9-羟基-6,10-二甲基-3-亚甲基-2-氧代环癸五烯并[B]呋喃-4-基酯,野马追内酯 K,野马追内酯K

STAT JAK/STAT signaling; Stem Cells
Eupalinolide K 是来自野马追的一种倍半萜内酯,是 STAT3抑制剂,可作为迈克尔反应受体。
TN1763 Ilexsaponin B3

冬青苷K,Ilexoside K

Others Others
Ilexoside K is a natural product from Ilex pubescens.
T2336 Vitamin K2

Menatetrenone,四烯甲萘醌

Endogenous Metabolite Metabolism
Vitamin K2 (Menatetrenone) 是内源性代谢产物的一种。
T20754 Deltamethrin

Butoss,RU-22974,Esbecythrin,溴氰菊酯,K-Othrin,Decamethrin,RU 22974

Others Others
Deltamethrin (RU 22974) 是一种具有神经毒性的拟除虫菊酯杀虫剂,在大鼠中能够产生一系列可逆的运动症状(如包括后肢僵硬、舞蹈性关节炎)。
T1719 Bufalin

ATPase Membrane transporter/Ion channel
Bufalin 是蟾酥中的一种成分,是Na+/K+-ATPase 抑制剂,具有抗肿瘤活性,可与其基 α1、α2 和 α3 结合,Kd 值分别为 42.5、45 和 40 nM。
T41124 Kizuta saponin K11

Others Others
Kizuta saponin K11 is a saponin derived from Kalopanax pictum var. maximowiczii leaves, which is a widely used Korean medicinal plant.
T2913 Schisantherin A

五味子酯甲,Schisanwilsonin H,Gomisin-C,Wuweizi ester-A,Schizantherin-A,Arisanschinin K

NF-κB NF-κB
Schisantherin A (Wuweizi ester-A) 是一种利用 IκBα 降解,抑制p65-NF-κB 易位进入细胞核的木脂素。
T20198 Potassium gluconate

Kalium-beta,Kalium Gluconate,Kaon elixir,Kaon,Potassium D-gluconate,HSDB 3165,K-Iao

Endogenous Metabolite; Antifungal Metabolism; Microbiology/Virology
Potassium gluconate (Potassium D-gluconate) 是一种具有口服活性和螯合性质的氧化型羧酸,具有杀菌活性。
T1075 Vitamin K1

Phylloquinone,维生素K1,叶绿醌,Phytomenadione,Phytonadione,Phyllohydroquinone

Others; Endogenous Metabolite Metabolism; Others
Vitamin K1 (Phylloquinone)是天然存在的维生素。Vitamin K1是血液凝固,骨和血管代谢所必须的。
T4898 Potassium 1-carboxyvinyl hydrogenphosphate

PEP-K,磷酸烯醇丙酮酸单钾盐,Phospho(enol)pyruvic acid monopotassium

Others; Endogenous Metabolite Metabolism; Others
Potassium 1-carboxyvinyl hydrogenphosphate (PEP-K) 是内源性代谢产物的一种。
T7106 Menaquinone-4

四烯甲萘醌,Vitamin K2,Menaquinone K4

Others; Endogenous Metabolite Metabolism; Others
Menaquinone-4 (Vitamin K2) 是维生素 K 的一种,用作止血剂,有潜力用于骨质疏松的研究。
TJP2872 Acevaltrate

Acevaltratum,乙酰缬草三酯,Acetoxyvaltrate

ATPase; Others Membrane transporter/Ion channel; Others
Acevaltrate (Acevaltratum) 对人小细胞肺癌细胞系 GLC(4) 和人结肠直肠癌细胞系 COLO 320 具有高细胞毒性,IC50 值为 1-6 uM。它抑制大鼠肾和脑半球中 Na+/K+-ATP 酶活性,IC50分别为 22.8 和 42.3 μM。
T7050 alpha-Tocopherolquinone

托可醌,Metarene

Antioxidant oxidation-reduction
alpha-Tocopherolquinone (Metarene) 会下调线粒体的呼吸活动。在还原为生育酚氢醌后,它还显示出抗氧化活性。在大鼠缺氧期间,已发现它的水平升高。
TN7565 Notoginsenoside K

Others Others
Notoginsenoside K 是一种三萜类天然产物,可以作为参考标准。
T79936 Forrestiacids K

ATP Citrate Lyase Metabolism
Forrestiacids K, 萜类化合物,源自Pseudotsuga forrestii,作为ATP-citrate lyase (ACL) 的抑制剂。
T83110 Angulatin K

Angulatin K为Celastrus angulatus根皮中发现的天然倍半萜多元醇酯。
T75480 Guignardone K

Others Others
Guignardone K,一种二萜化合物,从内生真菌(Guignardia sp.)的固体培养物中分离出来,具有抗真菌活性。
T81701 Nardoguaianone K

10-epi-Nardoguaianone J

Nardoguaianone K,一种从Nardostachys chinensis根中分离得到的愈创木脂类化合物,用于胰腺癌研究。
T79998 Celosin K

Apoptosis Apoptosis
Celosin K,一种可从Semen Celosiae的种子中分离得到的化合物,有效抑制t-BHP引起的神经元损伤。该化合物通过抑制氧化应激、细胞凋亡和自噬过程发挥作用。
T81972 Kuwanon K

Kuwanon K为从Morus Lhou分离得到的天然化合物。
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天然产物

Hosenkoside K
Cat.No: T5S2309
Synonym: 凤仙萜四醇苷K,(+)-Hosenkoside K
Target: Others
Ginkgolide K
Cat.No: T8200
Synonym: 银杏内酯 K,银杏内酯K
Target: AMPK, Autophagy
Vitamin K
Cat.No: T19603
Synonym: Kephton,维生素K,Vitamin K1(20)
Target: Endogenous Metabolite
Ginsenoside C-K
Cat.No: T3811
Synonym: 20(S)-人参皂苷 C-K,Ginsenoside compound K,Ginsenoside K,人参皂苷 C-K
Target: P450, cell cycle arrest, COX, NO Synthase
Menadione
Cat.No: T0449
Synonym: 维生素K3,Vitamin K3,甲萘醌
Target: Thrombin, Endogenous Metabolite
Vitamin K4
Cat.No: T2570
Synonym: 维生素K4,维生素 K4,Kapilin,Menadiol Diacetate,acetomenaphthone
Target: Apoptosis, Endogenous Metabolite
Yadanzioside K
Cat.No: TN5268
Synonym:
Target: Others
Terrestrosin K
Cat.No: TN2266
Synonym:
Target: Others
Kushenol K
Cat.No: TN1843
Synonym:
Target: PDE, HSV
Angelol K
Cat.No: TN1388
Synonym:
Target: Others
Momordicoside K
Cat.No: TN1945
Synonym:
Target: Others
Nepasaikosaponin K
Cat.No: T75675
Synonym:
Target: Antiviral
Sculponeatin K
Cat.No: TN4971
Synonym:
Target: Others
Epimedonin K
Cat.No: TN5664
Synonym:
Target:
Grossamide K
Cat.No: TN6589
Synonym:
Target:
Derrisisoflavone K
Cat.No: TN5465
Synonym:
Target:
Chlorovaltrate K
Cat.No: TN3646
Synonym:
Target: Others
Sanggenone K
Cat.No: TN4942
Synonym:
Target: Others
Macrocarpal K
Cat.No: TN4481
Synonym:
Target: Others
K-252c
Cat.No: T15638
Synonym:
Target: PKC
k-Strophanthoside
Cat.No: TN4362
Synonym:
Target: Others
Platycoside K
Cat.No: TN4805
Synonym:
Target: Others
Mulberrofuran K
Cat.No: TN4589
Synonym:
Target: Others
Epimedin K
Cat.No: TN3971
Synonym:
Target: Others
Mumeose K
Cat.No: TN5846
Synonym:
Target:
K-252b
Cat.No: T15637
Synonym:
Target: PKC
5-Dehydroxyparatocarpin K
Cat.No: TN3105
Synonym:
Target: Others
K 41
Cat.No: T25563
Synonym: K-41,K41,Antibiotic K-41A,37454 RP,Antibiotic A 32887
Target: Others
K-252a
Cat.No: T15636
Synonym: Antibiotic K 252a,Antibiotic SF 2370,SF2370
Target: Others
Ganoderic acid K
Cat.No: TN4103
Synonym:
Target:
Eupalinolide K
Cat.No: TN1631
Synonym: [3AR-[3AR*,4R*(E),6E,9S*,10E,11AR*]]-4-羟基-2-甲基-2-丁烯酸 2,3,3A,4,5,8,9,11A-八氢-9-羟基-6,10-二甲基-3-亚甲基-2-氧代环癸五烯并[B]呋喃-4-基酯,野马追内酯 K,野马追内酯K
Target: STAT
Ilexsaponin B3
Cat.No: TN1763
Synonym: 冬青苷K,Ilexoside K
Target: Others
Vitamin K2
Cat.No: T2336
Synonym: Menatetrenone,四烯甲萘醌
Target: Endogenous Metabolite
Deltamethrin
Cat.No: T20754
Synonym: Butoss,RU-22974,Esbecythrin,溴氰菊酯,K-Othrin,Decamethrin,RU 22974
Target: Others
Bufalin
Cat.No: T1719
Synonym:
Target: ATPase
Kizuta saponin K11
Cat.No: T41124
Synonym:
Target: Others
Schisantherin A
Cat.No: T2913
Synonym: 五味子酯甲,Schisanwilsonin H,Gomisin-C,Wuweizi ester-A,Schizantherin-A,Arisanschinin K
Target: NF-κB
Potassium gluconate
Cat.No: T20198
Synonym: Kalium-beta,Kalium Gluconate,Kaon elixir,Kaon,Potassium D-gluconate,HSDB 3165,K-Iao
Target: Endogenous Metabolite, Antifungal
Vitamin K1
Cat.No: T1075
Synonym: Phylloquinone,维生素K1,叶绿醌,Phytomenadione,Phytonadione,Phyllohydroquinone
Target: Others, Endogenous Metabolite
Potassium 1-carboxyvinyl hydrogenphosphate
Cat.No: T4898
Synonym: PEP-K,磷酸烯醇丙酮酸单钾盐,Phospho(enol)pyruvic acid monopotassium
Target: Others, Endogenous Metabolite
Menaquinone-4
Cat.No: T7106
Synonym: 四烯甲萘醌,Vitamin K2,Menaquinone K4
Target: Others, Endogenous Metabolite
Acevaltrate
Cat.No: TJP2872
Synonym: Acevaltratum,乙酰缬草三酯,Acetoxyvaltrate
Target: ATPase, Others
alpha-Tocopherolquinone
Cat.No: T7050
Synonym: 托可醌,Metarene
Target: Antioxidant
Notoginsenoside K
Cat.No: TN7565
Synonym:
Target: Others
Forrestiacids K
Cat.No: T79936
Synonym:
Target: ATP Citrate Lyase
Angulatin K
Cat.No: T83110
Synonym:
Target:
Guignardone K
Cat.No: T75480
Synonym:
Target: Others
Nardoguaianone K
Cat.No: T81701
Synonym: 10-epi-Nardoguaianone J
Target:
Celosin K
Cat.No: T79998
Synonym:
Target: Apoptosis
Kuwanon K
Cat.No: T81972
Synonym:
Target:
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Cat. No. Product Name Species Expression System
TMPY-06056 KRAS Protein, Human, Recombinant (G12D, His)

KRAS1,K-RAS4B,Kirsten rat sarcoma...

Human E. coli
KRAS Protein, Human, Recombinant (G12D, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22 kDa and the accession number is P01116-2.
TMPY-04113 KRAS Protein,Human,Recombinant(G12D & Q61H, His)

Kirsten rat sarcoma viral oncogene homolog,K

Human E. coli
KRAS Protein,Human,Recombinant(G12D & Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01116-2.
TMPY-04116 KRAS Protein,Human,Recombinant(G12C & Q61H, His)

NS,CFC2,K-RAS4B,C-K-RAS,KRAS2,

Human E. coli
KRAS Protein,Human,Recombinant(G12C & Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01116-2.
TMPY-01888 KRAS Protein,Human, Recombinant (Q61H, His)

KRAS2,C-K-RAS,Kirsten rat sarcoma...

Human E. coli
KRAS Protein,Human, Recombinant (Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22.5 kDa and the accession number is P01116-2.
TMPY-06567 Granzyme K/GZMK Protein, Human, Recombinant (His)

granzyme K,TRYP2

Human HEK293 Cells
Granzyme K/GZMK Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.56 kDa and the accession number is NP_002095.1.
TMPH-02689 Granzyme K/GZMK Protein, Mouse, Recombinant (His & Myc)

Gzmk,Granzyme K

Mouse E. coli
Granzyme K/GZMK Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli with N-terminal 10xHis tag and C-terminal Myc tag. The predicted molecular weight is 33.9 kDa. Accession number: O35205
TMPY-01050 Cadherin 6/CDH6 Protein, Human, Recombinant (His)

CAD6,cadherin 6, type 2, K-cadherin (fetal k

Human HEK293 Cells
Cadherin 6/CDH6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 68 kDa and the accession number is P55285-1.
TMPH-03262 Cathepsin K Protein, Rat, Recombinant (His)

CTSO,CTSO2,Cathepsin O2,Cathepsin X,Cathepsin O,CTSK

Rat E. coli
Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen.
TMPH-02565 Cathepsin K Protein, Mouse, Recombinant (His)

Cathepsin O,Cathepsin K,CTSK,Cathepsin O2,...

Mouse E. coli
Thiol protease involved in osteoclastic bone resorption. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen. Cathepsin K Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 27.4 kDa and the accession number is P...
TMPH-01061 Cathepsin K Protein, Human, Recombinant (His)

CTSO2,Cathepsin X,Cathepsin O2,CTSK,Cathepsin O,Cat...

Human E. coli
Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen. Cathepsin K Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The pre...
TMPY-05004 FGF-4 Protein, Human, Recombinant

HST-1,KFGF,fibroblast growth factor 4,HSTF1,K

Human E. coli
FGF (fibroblast growth factor) signalling is known to be required for many aspects of mesoderm formation and patterning during Xenopus development and has been implicated in regulating genes required for the specification of both blood and skeletal muscle lineages. Fibroblast growth factor 4 (FGF4) signaling induces differentiation from embryonic stem cells (ESCs) via the phosphorylation of downstream molecules such as mitogen-activated protein kinase/extracellular signal-related kinase (MEK) a...
TMPY-05414 NKG2D/CD314 Protein, Mouse, Recombinant (hFc)

D6H12S2489E,NKG2-D,killer cell lectin-li

Mouse Baculovirus Insect Cells
NKG2D/CD314 Protein, Mouse, Recombinant (hFc) is expressed in Baculovirus insect cells with hFc tag. The predicted molecular weight is 44.9 kDa and the accession number is O54709-2.
TMPY-03376 NKG2D/CD314 Protein, Rhesus, Recombinant (aa 78-216, His)

NKG2-D,NKG2D,KLRK1,k...

Rhesus Baculovirus Insect Cells
NKG2D/CD314 Protein, Rhesus, Recombinant (aa 78-216, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 18.3 kDa and the accession number is P61252.
TMPY-03256 NKG2D/CD314 Protein, Human, Recombinant (aa 78-216, His)

KLR,killer cell lectin-like recep...

Human Baculovirus Insect Cells
NKG2D/CD314 Protein, Human, Recombinant (aa 78-216, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 18.4 kDa and the accession number is P26718-1.
TMPY-00467 NKG2D/CD314 Protein, Human, Recombinant (hFc)

D12S2489E,killer cell lectin-like receptor...

Human CHO Cells
NKG2D/CD314 Protein, Human, Recombinant (hFc) is expressed in CHO mammalian cells with hFc tag. The predicted molecular weight is 46.5 kDa and the accession number is A0A024RAP8.
TMPH-02699 H2-K1 Protein, Mouse, Recombinant (GST)

H-2 class I histocompatibility antigen, K-D alpha c...

Mouse E. coli
Involved in the presentation of foreign antigens to the immune system.
TMPK-01510 HLA-A*03:01&B2M&KRAS WT (VVVGAGGVGK) Tetramer Protein, Human, MHC (His & Avi)

NS,NS3,KRAS2,RASK2,MHC,RALD,K-Ras...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target.
TMPK-01463 HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Monomer Protein, Human, MHC (His & Avi)

C-K-RAS,KI-RAS,KRAS1,K-R...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01429 HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated

MHC,K-Ras 2,NS,K-RAS4A,KRAS,NS3,<...

Human E. coli
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01518 HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Tetramer Protein, Human, MHC (His & Avi)

MHC,NS,KRAS1,K-RAS2A,GTPase Kras,...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01527 HLA-A*03:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (His & Avi)

NS,RALD,C-K-RAS,RASK2,K-RAS2B,

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01408 HLA-A*02:01&B2M&KRAS G12V (KLVVVGAVGV) Monomer Protein, Human, MHC (His & Avi), Biotinylated

RALD,KRAS1,KRAS2,K-RAS2B,CFC2,NS3...

Human E. coli
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01433 HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Tetramer Protein, Human, MHC (His & Avi)

GTPase Kras,NS3,K-Ras 2,K-RAS2B,R...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01401 HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi)

MHC,CFC2,K-Ras 2,RALD,K-RAS4A,NS,RASK<...

Human E. coli
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target.
TMPK-01488 HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein, Human, MHC (His & Avi)

K-RAS4A,MHC,GTPase Kras,K-Ras 2,<...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target.
TMPK-01458 HLA-A*11:01&B2M&KRAS G12A (VVVGAAGVGK) Monomer Protein, Human, MHC (His & Avi)

K-Ras 2,GTPase Kras,KRAS2,MHC,

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01451 HLA-C 03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi)

NS3,K-RAS4A,K-Ras 2,NS,KRAS1,RAS<...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01529 HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Monomer Protein, Human, MHC (His & Avi)

K-RAS4A,KRAS1,MHC,K-RAS2B,CFC2,GT...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-00596 SECTM1 Protein, Human, Recombinant (hFc)

SECTM1,K-12

Human HEK293 Cells
SECTM1 is a T/NK cell "co-stimulatory" molecule that is expressed in the peripheral blood by neutrophils and monocytes.Human monocytic cells also displayed a pronounced negative regulation of SECTM1 mRNA expression by LPS, while at the protein level SECTM1 expression was also shown to be regulated by IFN and LPS. This tight regulation of SECTM1 gene expression and rapid upregulation highlights its relevance in the innate immune response.
TMPK-01489 HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Tetramer Protein, Human, MHC (His & Avi)

K-RAS2A,NS3,KRAS1,KRAS2,MHC,NS,

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target.
TMPK-01526 HLA-A*03:01&B2M&KRAS G12V (VVVGAVGVGK) Tetramer Protein, Human, MHC (His & Avi)

KRAS,NS3,GTPase Kras,RASK2,K<...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01490 HLA-A*11:01&B2M&KRAS G12V (VVGAVGVGK) Monomer Protein, Human, MHC (His & Avi)

K-RAS2A,GTPase Kras,K-Ras 2,RALD,...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01453 HLA-A*03:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated

RASK2,CFC2,K-Ras 2,NS3,GTPase Kra...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01464 HLA-A*11:01&B2M&KRAS G12R (VVVGARGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated

C-K-RAS,K-RAS4A,GTPase Kras,K...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01537 HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated

K-RAS4A,NS,C-K-RAS,RALD,GTPase Kr...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01536 HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated

NS3,MHC,KRAS,RALD,CFC2,K-RAS2B,GTPase ...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01400 HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated

NS,KRAS1,RALD,K-RAS2A,K-RAS2B,

Human E. coli
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target.
TMPK-01457 HLA-A*11:01&B2M&KRAS G12A (VVVGAAGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated

K-Ras 2,CFC2,RALD,MHC,KRAS,K-RAS4...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01471 HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein, Human, MHC (His & Avi), FITC-Labeled

CFC2,KRAS,K-RAS4B,MHC,K-RAS2B,

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target.
TMPK-01431 HLA-A*11:01&B2M&KRAS G12S (VVVGASGVGK) Tetramer Protein, Human, MHC (His & Avi)

RALD,C-K-RAS,MHC,K-RAS2A,GTPase K...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01407 HLA-A*02:01&B2M&KRAS WT (KLVVVGAGGV) Monomer Protein, Human, MHC (His & Avi), Biotinylated

KRAS2,RALD,C-K-RAS,NS3,MHC,CFC2,K...

Human E. coli
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target.
TMPK-01439 HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled

KRAS,GTPase Kras,K-RAS2A,K

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPY-00972 FGFR2 Protein, Human, Recombinant (His & hFc)

K-SAM,TK14,BBDS,fibroblast growth factor r...

Human HEK293 Cells
FGFR2 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 67.6 kDa and the accession number is P21802-1.
TMPY-00423 FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc)

BFR-1,KGFR,TK25,JWS,ECT1,K-SAM,FG...

Human HEK293 Cells
FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66.3 kDa and the accession number is P21802-17.
TMPK-01404 HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated

NS,KRAS,KRAS1,KRAS2,MHC,RALD,...

Human E. coli
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01434 HLA-A*11:01&B2M&KRAS G12R (VVVGARGVGK) Tetramer Protein, Human, MHC (His & Avi)

RASK2,CFC2,GTPase Kras,KRAS,K...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01525 HLA-A*11:01&B2M&KRAS G12V (VVGAVGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated

CFC2,RALD,K-Ras 2,MHC,C-K-RAS,NS3,GTPase <...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01403 HLA-A*11:01&B2M&KRAS G12V (VVGAVGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi)

K-Ras 2,KI-RAS,CFC2,KRAS1,GTPase ...

Human E. coli
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01399 HLA-A*11:01&B2M&KRAS WT (VVGAGGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated

K-RAS2A,NS3,KRAS2,CFC2,K-RAS4B,GT...

Human E. coli
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target.
TMPK-01461 HLA-A*11:01&B2M&KRAS G12S (VVVGASGVGK) Monomer Protein, Human, MHC (His & Avi)

C-K-RAS,KRAS,RASK2,K-Ras...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
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重组蛋白

KRAS Protein, Human, Recombinant (G12D, His)
Cat.No: TMPY-06056
Species: Human
Expression System: E. coli
KRAS Protein,Human,Recombinant(G12D & Q61H, His)
Cat.No: TMPY-04113
Species: Human
Expression System: E. coli
KRAS Protein,Human,Recombinant(G12C & Q61H, His)
Cat.No: TMPY-04116
Species: Human
Expression System: E. coli
KRAS Protein,Human, Recombinant (Q61H, His)
Cat.No: TMPY-01888
Species: Human
Expression System: E. coli
Granzyme K/GZMK Protein, Human, Recombinant (His)
Cat.No: TMPY-06567
Species: Human
Expression System: HEK293 Cells
Granzyme K/GZMK Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02689
Species: Mouse
Expression System: E. coli
Cadherin 6/CDH6 Protein, Human, Recombinant (His)
Cat.No: TMPY-01050
Species: Human
Expression System: HEK293 Cells
Cathepsin K Protein, Rat, Recombinant (His)
Cat.No: TMPH-03262
Species: Rat
Expression System: E. coli
Cathepsin K Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02565
Species: Mouse
Expression System: E. coli
Cathepsin K Protein, Human, Recombinant (His)
Cat.No: TMPH-01061
Species: Human
Expression System: E. coli
FGF-4 Protein, Human, Recombinant
Cat.No: TMPY-05004
Species: Human
Expression System: E. coli
NKG2D/CD314 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-05414
Species: Mouse
Expression System: Baculovirus Insect Cells
NKG2D/CD314 Protein, Rhesus, Recombinant (aa 78-216, His)
Cat.No: TMPY-03376
Species: Rhesus
Expression System: Baculovirus Insect Cells
NKG2D/CD314 Protein, Human, Recombinant (aa 78-216, His)
Cat.No: TMPY-03256
Species: Human
Expression System: Baculovirus Insect Cells
NKG2D/CD314 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00467
Species: Human
Expression System: CHO Cells
H2-K1 Protein, Mouse, Recombinant (GST)
Cat.No: TMPH-02699
Species: Mouse
Expression System: E. coli
HLA-A*03:01&B2M&KRAS WT (VVVGAGGVGK) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01510
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01463
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated
Cat.No: TMPK-01429
Species: Human
Expression System: E. coli
HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01518
Species: Human
Expression System: HEK293 Cells
HLA-A*03:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01527
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&KRAS G12V (KLVVVGAVGV) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01408
Species: Human
Expression System: E. coli
HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01433
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi)
Cat.No: TMPK-01401
Species: Human
Expression System: E. coli
HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01488
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12A (VVVGAAGVGK) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01458
Species: Human
Expression System: HEK293 Cells
HLA-C 03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01451
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01529
Species: Human
Expression System: HEK293 Cells
SECTM1 Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00596
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01489
Species: Human
Expression System: HEK293 Cells
HLA-A*03:01&B2M&KRAS G12V (VVVGAVGVGK) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01526
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12V (VVGAVGVGK) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01490
Species: Human
Expression System: HEK293 Cells
HLA-A*03:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01453
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12R (VVVGARGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01464
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01537
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01536
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated
Cat.No: TMPK-01400
Species: Human
Expression System: E. coli
HLA-A*11:01&B2M&KRAS G12A (VVVGAAGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01457
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein, Human, MHC (His & Avi), FITC-Labeled
Cat.No: TMPK-01471
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12S (VVVGASGVGK) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01431
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&KRAS WT (KLVVVGAGGV) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01407
Species: Human
Expression System: E. coli
HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled
Cat.No: TMPK-01439
Species: Human
Expression System: HEK293 Cells
FGFR2 Protein, Human, Recombinant (His & hFc)
Cat.No: TMPY-00972
Species: Human
Expression System: HEK293 Cells
FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc)
Cat.No: TMPY-00423
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated
Cat.No: TMPK-01404
Species: Human
Expression System: E. coli
HLA-A*11:01&B2M&KRAS G12R (VVVGARGVGK) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01434
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12V (VVGAVGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01525
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12V (VVGAVGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi)
Cat.No: TMPK-01403
Species: Human
Expression System: E. coli
HLA-A*11:01&B2M&KRAS WT (VVGAGGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01399
Species: Human
Expression System: E. coli
HLA-A*11:01&B2M&KRAS G12S (VVVGASGVGK) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01461
Species: Human
Expression System: HEK293 Cells
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Cat. No. Product Name Target Signaling Pathways
TMIJ-0422 Benzo[k]fluoranthene-d12

Benzo[k]fluoranthene-d12 是 Benzo[k]fluoranthene 的氘代化合物。Benzo[k]fluoranthene 的 CAS 号为 207-08-9。
TMID-0302 Vitamin K3-d3

Vitamin K3-d3 是 Vitamin K3 的氘代化合物。Vitamin K3 的 CAS 号为 58-27-5。Menadione是合成的萘醌,能够在体内转化成活性维生素K2。
TMIH-0599 Vitamin K1-d7

Vitamin K1-d7 是 Vitamin K1 的氘代化合物。
TMIH-0600 Vitamin K3-d8

Vitamin K3-d8 是 Vitamin K3 的氘代化合物。
TMID-0001 Vitamin K1-d4

Vitamin K1-d4 是 Vitamin K1 的氘代化合物。Vitamin K1 的 CAS 号为 84-80-0。Vitamin K1 (Phylloquinone) 是天然存在的维生素。Vitamin K1是血液凝固,骨和血管代谢所必须的。
T40376 L-Phenylalanine-15N

L-苯丙氨酸 15N,(S)-2-Amino-3-phenylpropionic acid-15N,L-Phenylalanine-15N

Calcium Channel Membrane transporter/Ion channel; Metabolism
L-Phenylalanine-15N ((S)-2-Amino-3-phenylpropionic acid-15N) 是 15N 标记的 L-Phenylalanine。L-Phenylalanine 是从大肠杆菌中分离出来的一种必需氨基酸。 L-Phenylalanine 广泛用于食品香精和药物的生产。
TMIJ-0074 Retigabine-d4

Retigabine-d4 是 Retigabine 的氘代化合物。Retigabine 的 CAS 号为 150812-12-7。Retigabine dihydrochloride 是一种抗惊厥药,用作有治疗经验的成年患者部分性癫痫的辅助治疗。作用机制涉及神经元 K(V)7.2-7.5(以前的 KCNQ2-5)电压激活 K(+) 通道的开放。
T12442 Phenindione D5

Rectadione D5,苯茚二酮 D5

Others Others
Phenindione D5 is deuterium labeled Phenindione, which functions as a Vitamin K antagonist.
T10633 Bumetanide-d5

Others Others
Bumetanide D5 is a deuterium-labeled Bumetanide. Bumetanide is a Na+-K+-Cl- (NKCC1) inhibitor (IC50s: 0.68 and 4.0 μM for hNKCC1A and hNKCC2A).
TMIH-0301 Levolansoprazole-d4

Levolansoprazole-d4 是 Levolansoprazole 的氘代化合物。Levolansoprazole 的 CAS 号为 138530-95-7。Levolansoprazole 是一种质子泵抑制剂,不可逆地抑制壁细胞中 H+/K+ 刺激的 ATPase 泵 (IC50: 5.2 µM)。它还抑制分离的犬壁细胞中的酸形成(IC50:82 µM)。 (R)-和 (S)-兰索拉唑均具有药理活性,具有相似的效力。
TMIH-0183 Dequalinium Chloride-d4

Dequalinium Chloride-d4 是 Dequalinium Chloride 的氘代化合物。Dequalinium Chloride 的 CAS 号为 522-51-0。Dequalinium chloride 是一种apamin敏感型的钾离子通道选择性阻断剂。
T37250 Cefazolin-13C2,15N

Cefazolin-13C2,15N

Cefazolin-13C2,15N is intended for use as an internal standard for the quantification of cefazolin by GC- or LC-MS. Cefazolin is a broad-spectrum cephalosporin antibiotic that is active in vitro against various Gram-positive and Gram-negative bacteria (MICs = 0.2-12.5 μg/ml). It also inhibits the growth of clinical isolates of S. aureus, E. coli, P. mirabilis, and K. pneumoniae (MICs = 0.1-25 μg/ml). In vivo, cefazolin protects against S. aureus, E. coli, and P. mirabilis infection in mice (ED50...
T73820 Bosentan-d4

Bosentan-d4 是 Bosentan 的氘代物。Bosentan 是一种有效的endothelin-1 (ET)拮抗剂,在人的 SMC 细胞中,作用于ETA 和ETB 受体,Ki 值分别为 4.7 nM 和 95 nM。
TMID-0040 Palmitoyl L-Carnitine-d3 Hydrochloride

Palmitoyl L-Carnitine-d3 Hydrochloride 是 Palmitoyl L-Carnitine Hydrochloride 的氘代化合物。Palmitoyl L-Carnitine Hydrochloride 的 CAS 号为 18877-64-0。L-Palmitoylcarnitine chloride (Palmitoyl-L-carnitine chloride)是一种脂肪酸代谢产物,具有抗血栓形成的作用,通过抵消tMCAO模型中的脑内血栓形成来保护小鼠免受缺血性中风。L-Palmitoylcarnitine chloride抑制心脏中的Na/K泵,抑制 FeCl 3诱导的动脉血栓形成,减轻了短暂性大脑中动脉闭塞(tMCAO)小鼠模型的脑内血栓形成和炎症。
TMID-0041 Menaquinone-9-d7

Vitamin K2-MK9-d7

Menaquinone-9-d7 是 Menaquinone-9 的氘代化合物。Menaquinone-9 的 CAS 号为 523-39-7。Menaquinone 9 (MK-9) 是一种维生素 K2 类似物,已在包括大肠杆菌在内的各种细菌中发现。Menaquinone 9 对紫外线敏感,可与细菌电子传输链的一种成分可溶性硝酸还原酶结合。
TMIJ-0138 Dronedarone-d6 HCl

Dronedarone-d6 HCl 是 Dronedarone HCl 的氘代化合物。Dronedarone HCl 的 CAS 号为 141625-93-6。Dronedarone Hydrochloride 是一种胺碘酮类似物,可抑制Na+,K+andCa2+的电流,有可能治疗心房颤动。
TMIJ-0503 Digoxin-d3

Digoxin-d3 是 Digoxin 的氘代化合物。Digoxin 的 CAS 号为 20830-75-5。Digoxin是Na+/K+-ATPase有效抑制剂,用于治疗各种心脏疾病。
TMIH-0469 Quinidine-d3

Quinidine-d3 是 Quinidine 的氘代化合物。Quinidine 的 CAS 号为 56-54-2。Quinidine 是一种抗心律失常剂,也是 K+通道的有效阻断剂,其IC50值为 19.9 μM。它是一种选择性细胞色素 P450db 的有效抑制剂,也可研究疟疾。
TMIH-0602 Vonoprazan-d4

Vonoprazan-d4 是 Vonoprazan 的氘代化合物。Vonoprazan 的 CAS 号为 881681-00-1。Vonoprazan 是一种质子泵抑制剂,是口服活性钾竞争性酸阻断剂,有抗分泌作用。在 pH 为 6.5 时,它抑制猪胃微粒体中的 H+,K+-ATPase 酶活性,IC50值为 19 nM。它可用于研究胃酸相关疾病。
TMIH-0601 Vonoprazan-d3

Vonoprazan-d3 是 Vonoprazan 的氘代化合物。Vonoprazan 的 CAS 号为 881681-00-1。Vonoprazan 是一种质子泵抑制剂,是口服活性钾竞争性酸阻断剂,有抗分泌作用。在 pH 为 6.5 时,它抑制猪胃微粒体中的 H+,K+-ATPase 酶活性,IC50值为 19 nM。它可用于研究胃酸相关疾病。
TMIJ-0192 Pantoprazole-d6

Pantoprazole-d6 是 Pantoprazole 的氘代化合物。Pantoprazole 的 CAS 号为 102625-70-7。Pantoprazole 是一种质子泵抑制剂,用于短期治疗由胃食管反流病引起的食管糜烂和溃疡。它联合阿霉素可显著增加肿瘤生长延迟。它是一种取代的苯并咪唑,是H+/K+-ATPase抑制剂,可改善 pH 值稳定性,具有抗分泌和抗溃疡的作用。
TMIH-0222 Esomeprazole sodium-d6

Esomeprazole sodium-d6 是 Esomeprazole sodium 的氘代化合物。Esomeprazole sodium 的 CAS 号为 161796-78-7。Esomeprazole sodium 是一种口服有效的活性质子泵抑制剂。Esomeprazole sodium通过抑制胃壁细胞中的H+, K+-ATPase来降低酸分泌,在胃食管反流疾病中有研究价值。Esomeprazole 是一种外泌体抑制剂,通过抑制 V-H+-ATPases 来阻断外泌体的释放。
T35789 Palmitic acid-1-13C

Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plasma lipids.1 It increases protein levels of COX-2 in RAW 264.7 cells when used at a concentration of 75 μM.2 Palmitic acid is involved in the acylation of proteins to anchor membrane-bound proteins to the lipid bilayer.2,3,4,5,6 |1. Santos, M.J., López-Jurado, M., Llopis, J., et a...
T35591 Guanfacine-13C,15N3

Guanfacine-13C,15N3

Guanfacine-13C,15N3is intended for us as an internal standard for the quantification of guanfacine by GC- or LC-MS. Guanfacine is an α2-adrenergic receptor (α2-AR) agonist with Kivalues of 93, 1,380, and 3,890 nM for α2A-, α2B-, and α2C-ARs, respectively, in a radioligand binding assay.1It has EC50values of 52, 288, and 602 nM for α2A-, α2B-, and α2C-ARs, respectively, for stimulated [35S]GTPγS binding. It also binds to imidazoline receptor 1 (Ki= 19 nM in a radioligand binding assay).2Guanfacin...
T36055 Nitisinone-13C6

Nitisinone-13C6

Nitisinone-13C6is intended for use as an internal standard for the quantification of nitisinone by GC- or LC-MS. Nitisinone is an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (HPPD), which converts 4-hydroxyphenylpyruvate (HPPA) to homogentisate in the tyrosine catabolic pathway.1Nitisinone increases urinary levels of HPPA and 4-hydroxyphenyllactate (HPLA) in rats when administered at a dose of 10 mg/kg. Nitisinone (3 mg/kg) prevents the neonatal lethality of fumarylacetoacetate hydrolase (F...
T35791 Palmitic acid-13C

Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid-13C contains 13C at the C2 position and has been used in the study of free fatty acid incorporation into phospholipid fatty acids in soil microbes.1 Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plasma lipids.2 It increases protein levels of COX-2 in RAW 264.7 cells when used at a concentration of 75 μM.3 Palmitic ...
T37847 Zonisamide-13C2,15N

Zonisamide-13C2,15N

Zonisamide-13C2,15N is intended for use as an internal standard for the quantification of zonisamide by GC- or LC-MS. Zonisamide is an antiepileptic agent.1 It selectively inhibits the repeated firing of sodium channels (IC50 = 2 μg/ml) in mouse embryo spinal cord neurons and inhibits spontaneous channel firing when used at concentrations greater than 10 μg/ml.2 In rat cerebral cortex neurons, zonisamide (1-1,000 μM) inhibits T-type calcium channels with a maximum reduction of 60% of the calcium...

同位素标记化合物

Benzo[k]fluoranthene-d12
Cat.No: TMIJ-0422
Synonym:
Target:
Vitamin K3-d3
Cat.No: TMID-0302
Synonym:
Target:
Vitamin K1-d7
Cat.No: TMIH-0599
Synonym:
Target:
Vitamin K3-d8
Cat.No: TMIH-0600
Synonym:
Target:
Vitamin K1-d4
Cat.No: TMID-0001
Synonym:
Target:
L-Phenylalanine-15N
Cat.No: T40376
Synonym: L-苯丙氨酸 15N,(S)-2-Amino-3-phenylpropionic acid-15N,L-Phenylalanine-15N
Target: Calcium Channel
Retigabine-d4
Cat.No: TMIJ-0074
Synonym:
Target:
Phenindione D5
Cat.No: T12442
Synonym: Rectadione D5,苯茚二酮 D5
Target: Others
Bumetanide-d5
Cat.No: T10633
Synonym:
Target: Others
Levolansoprazole-d4
Cat.No: TMIH-0301
Synonym:
Target:
Dequalinium Chloride-d4
Cat.No: TMIH-0183
Synonym:
Target:
Cefazolin-13C2,15N
Cat.No: T37250
Synonym: Cefazolin-13C2,15N
Target:
Bosentan-d4
Cat.No: T73820
Synonym:
Target:
Palmitoyl L-Carnitine-d3 Hydrochloride
Cat.No: TMID-0040
Synonym:
Target:
Menaquinone-9-d7
Cat.No: TMID-0041
Synonym: Vitamin K2-MK9-d7
Target:
Dronedarone-d6 HCl
Cat.No: TMIJ-0138
Synonym:
Target:
Digoxin-d3
Cat.No: TMIJ-0503
Synonym:
Target:
Quinidine-d3
Cat.No: TMIH-0469
Synonym:
Target:
Vonoprazan-d4
Cat.No: TMIH-0602
Synonym:
Target:
Vonoprazan-d3
Cat.No: TMIH-0601
Synonym:
Target:
Pantoprazole-d6
Cat.No: TMIJ-0192
Synonym:
Target:
Esomeprazole sodium-d6
Cat.No: TMIH-0222
Synonym:
Target:
Palmitic acid-1-13C
Cat.No: T35789
Synonym:
Target:
Guanfacine-13C,15N3
Cat.No: T35591
Synonym: Guanfacine-13C,15N3
Target:
Nitisinone-13C6
Cat.No: T36055
Synonym: Nitisinone-13C6
Target:
Palmitic acid-13C
Cat.No: T35791
Synonym:
Target:
Zonisamide-13C2,15N
Cat.No: T37847
Synonym: Zonisamide-13C2,15N
Target:
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