4
2
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3363L |
Jervine HCl
Jervine hydrochloride |
Others | Others |
Jervine is a naturally occurring steroidal alkaloid derived from the Veratrum plant species. Over the Hedgehog signaling pathway, Jervine effectively inhibits tumor growth using three human tumor xenograft models. Jervine has the potential to advance to t | |||
T31415 |
Diacetyljervine
NSC-406352,NSC 406352,N-acetyl-,N,O-Diacetyljervine,Jervine,NSC406352 |
Others | Others |
Diacetyljervine is a bioactive chemical. | |||
T33767 |
O-Acetyljervine
3-O-Acetyljervine |
Others | Others |
O-Acetyljervine is a bioactive chemical. | |||
T34821 |
Tetrahydrojervine
|
Others | Others |
Tetrahydrojervine is a bioactive chemical. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3363 |
Jervine
蒜黎芦碱,Iervin,11-Ketocyclopamine,Jerwiny |
Hedgehog/Smoothened; Smo | GPCR/G Protein; Stem Cells |
Jervine (Jerwiny) 是一种有效的刺猬 (Hh) 抑制剂(IC50:500-700 nM)。它是一种天然致畸性甾体生物碱,来自于 Veratrumalbum 的根茎,具有抗炎和抗氧化作用。 | |||
TN2343 |
Pseudojervine
Jervin-3-glucoside,O-beta-D-Glucopyranosyljervine,假白藜芦碱 |
Platelet aggregation | Others |
Pseudojervine (O-beta-D-Glucopyranosyljervine) 来源于 Veratrum nigrum L. Pseudojervine 对血小板聚集表现出微弱的抑制活性。 |