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Search Results for " isoleucine "

Targets Recommended: Others

19

抑制剂 & 化合物

9

天然产物

4

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T67562	Fmoc-Ile-OH Fmoc-L-isoleucine	Others	Others
	Fmoc-Ile-OH (Fmoc-L-isoleucine) 是一种 Fmoc 修饰的异亮氨酸，对肽和蛋白质具有很强的亲和力，可用于合成其他有活性的化合物。
T32212	Isoleucine orlistat, L- L-Isoleucine orlistat,Orlistat related compound E	Others	Others
	Isoleucine orlistat, L- is a bioactive chemical.
T33867	Palmitoyl isoleucine	Others	Others
	Palmitoyl isoleucine is a lipo-aminoacid derived from the naturally occurring essential amino acid isoleucine.
T33080	Lysyl aspartyl isoleucine Tripeptide-10,Lys-asp-ile
	Lysyl aspartyl isoleucine（Tripeptide-10）是一种生物活性肽，具有抗皱作用，已被报道用作化妆品成分
T31710	Ethyl L-isoleucinate HCl Isoleucine ethyl ester hydrochloride,L-Isoleucine ethyl ester HCl	Others	Others
	L-Isoleucine ethyl ester HCl is a bioactive chemical.
T74190	(-)-Jasmonoyl-L-isoleucine	Others	Others
	(-)-Jasmonoyl-L-isoleucine ((-)-JA-L-Ile)，为(+)-JA-L-Ile的对映体，是一种无活性的内源性激素。
T65964	N-Methyl-L-isoleucine	Others	Others
	N-Methyl-L-isoleucine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65964，CAS号为 4125-98-8。
T66684	Boc-L-isoleucine hemihydrate	Others	Others
	Boc-L-isoleucine hemihydrate 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66684，CAS号为 204138-23-8。
T25767	Lysobactin Katanosin A, 7-L-isoleucine-,Katanosin B
	Lysobactin, also known as katanosin B, is an effective antibiotic with in vivo efficacy against Staphylococcus aureus and Streptococcus pneumoniae. It was previously shown to inhibit peptidoglycan (PG) biosynthesis.
T72045	Fmoc-N-methyl-L-alloisoleucine	Others	Others
	Fmoc-N-methyl-L-alloisoleucine是一种生化试剂，可用于生物合成。
T34140	Prolylisoleucine Pro-ile	Others	Others
	Prolylisoleucine is a derivative of isoleucine that is used in the biosynthesis of proteins.
T22043	BCATc Inhibitor 2	Others	Others
	BCATc Inhibitor 2 是选择性分支链氨基转移酶抑制剂，可用于神经退行性疾病的研究。能够抑制 rBCATc (IC50:0.2 μM)，hBCATc (IC50:0.8 μM)、 rBCATm (IC50:3.0 μM)。其中BCATc 也称为 BCAT1，存在于细胞质基质中的亚型。
T31888	Furanomycin NSC 116328,NSC116328,NSC-116328	Others	Others
	Furanomycin is an analog of isoleucine.
T63376	CB 168	Others	Others
	CB 168是有效的靶向异亮基 tRNA 合成酶 (IleRS) 选择性氨基酰基氨基酰芳基四唑抑制剂。
T80096	L-Isoleucyl-L-arginine	Angiotensin-converting Enzyme (ACE)	Metabolism
	L-Isoleucyl-L-arginine为由L-异亮氨酸和L-精氨酸残基组成的二肽，是一种有效的血管紧张素转换酶(ACE)抑制剂，通常应用于高血压的研究领域。
T68440	Epicriptine	Others	Others
	Epicriptine or beta-dihydroergocryptine is a dopamine agonist of the ergoline class. It constitutes one third of the mixture known as dihydroergocryptine, the other two thirds consisting of alpha-dihydroergocryptine. The alpha differs from the beta form only in the position of a single methyl group, which is a consequence of the biosynthesis in which the proteinogenic amino acid isoleucine is replaced by leucine.
T76108	Leucine dehydrogenase	Others	Others
	Leucine dehydrogenase 能够从球形芽孢杆菌中纯化得到。Leucine dehydrogenase 催化L-亮氨酸、L-缬氨酸、L-异亮氨酸、L-去甲缬氨酸、左旋α-氨基丁酸酯和L-去甲亮氨酸的氧化脱氨，以及它们的酮类似物的还原胺化。
T75292	Biotin sodium	Others	Others
	Biotin (Vitamin B7) sodium 是一种水溶性维生素 B，是人体五种羧化酶的辅酶，参与脂肪酸、异亮氨酸和缬氨酸的合成，并参与糖异生。Biotin sodium 是细胞生长、脂肪酸产生以及脂肪和氨基酸代谢的必需物质。
T36722	Deltorphin II (trifluoroacetate salt)	Others	Others
	Deltorphin II is a peptide agonist of δ2-opioid receptors.1,2It is selective for δ-opioid receptors over μ- and κ-opioid receptors in radioligand bindings assays (Kis = 0.0033, >1, and >1 μM, respectively) and induces [35S]GTPγS binding in mouse brain membrane preparations (EC50= 0.034 μM). Deltorphin II (0.12 mg/kg) decreases the infarction zone:risk zone ratio in a rat model of myocardial ischemia-reperfusion injury induced by coronary occlusion, an effect that can be reversed by the δ2-opioid...

化合物

Cat.No: T67562

Synonym: Fmoc-L-isoleucine

Target: Others

Isoleucine orlistat, L-

Cat.No: T32212

Synonym: L-Isoleucine orlistat,Orlistat related compound E

Target: Others

Palmitoyl isoleucine

Cat.No: T33867

Target: Others

Lysyl aspartyl isoleucine

Cat.No: T33080

Synonym: Tripeptide-10,Lys-asp-ile

Ethyl L-isoleucinate HCl

Cat.No: T31710

Synonym: Isoleucine ethyl ester hydrochloride,L-Isoleucine ethyl ester HCl

Target: Others

(-)-Jasmonoyl-L-isoleucine

Cat.No: T74190

Target: Others

N-Methyl-L-isoleucine

Cat.No: T65964

Target: Others

Boc-L-isoleucine hemihydrate

Cat.No: T66684

Target: Others

Cat.No: T25767

Synonym: Katanosin A, 7-L-isoleucine-,Katanosin B

Fmoc-N-methyl-L-alloisoleucine

Cat.No: T72045

Target: Others

Prolylisoleucine

Cat.No: T34140

Synonym: Pro-ile

Target: Others

BCATc Inhibitor 2

Cat.No: T22043

Target: Others

Cat.No: T31888

Synonym: NSC 116328,NSC116328,NSC-116328

Target: Others

Cat.No: T63376

Target: Others

L-Isoleucyl-L-arginine

Cat.No: T80096

Target: Angiotensin-converting Enzyme (ACE)

Cat.No: T68440

Target: Others

Leucine dehydrogenase

Cat.No: T76108

Target: Others

Cat.No: T75292

Target: Others

Deltorphin II (trifluoroacetate salt)

Cat.No: T36722

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T0063	L-Isoleucine 异亮氨酸,isoleucine,Ile,L-异亮氨酸	Amino Acids and Derivatives; Endogenous Metabolite	Metabolism
	L-Isoleucine (Ile) 是一种非极性疏水性氨基酸。它是必需氨基酸。
T9143	D-Isoleucine (2R,3R)-2-Amino-3-methylpentanoic acid,D-异亮氨酸,(R)-Isoleucine	Others	Others
	D-Isoleucine ((2R,3R)-2-Amino-3-methylpentanoic acid) 是一种异亮氨酸立体异构体，是 Asc-1 反转运蛋白的选择性激活剂。它能够释放内源性 D-丝氨酸，提高海马 CA1-CA3 的长期增效作用。
T5219	L-Alloisoleucine L-别异亮氨酸,L-allo-Isoleucine,(3R)-LS-Isoleucine,L(+)-Alloisoleucine	Others; Endogenous Metabolite	Metabolism; Others
	L-Alloisoleucine (L-allo-Isoleucine) 是 L-异亮氨酸的立体异构体，是一种支链氨基酸，是人血浆的常见成分 (尽管水平较低)。
T7448	4-Hydroxyisoleucine 4-羟基-L-异亮氨酸,4-Hydroxy-L-isoleucine	Others	Others
	4-Hydroxyisoleucine (4-Hydroxy-L-isoleucine) 是从胡芦巴种子中提取和纯化的一种氨基酸，具有促胰岛素作用。
T2P2919	(2S,3R,4S)-4-Hydroxyisoleucine (4S)-4-Hydroxy-L-isoleucine,(4S)4-羟基异亮氨酸,Hydroxyisoleucine	PI3K	PI3K/Akt/mTOR signaling
	(2S,3R,4S)-4-Hydroxyisoleucine (Hydroxyisoleucine) 是分离自胡芦巴中的一种可口服的有效成分，具有抗糖尿病、抗糖尿病肾病的作用。
T4851	Methyl acetylacetate Methyl acetoacetate,乙酰乙酸甲酯	Others; Endogenous Metabolite	Metabolism; Others
	Methyl acetylacetate (Methyl acetoacetate) 是内源性代谢产物的一种。
T2O2731	L-Aspartic acid L-天冬氨酸,L-天冬氨酸；L-天冬碱;L-酰胺天冬酸；L-天冬酰胺一水物,Aspatofort,Asparagic acid	Others; Endogenous Metabolite	Metabolism; Others
	L-Aspartic acid (Aspatofort) 是一种氨基酸，是结肠特异性药物输送的前体药物。
T5306	H-Abu-OH L-2-氨基丁酸,L-Aminobutyric Acid,L-α-amino-n-Butyric acid,L(+)-2-Aminobutyric acid	Others; Endogenous Metabolite	Metabolism; Others
	H-Abu-OH (L-α-amino-n-Butyric acid) 是氨基丁酸的三个同分异构体之一，它在患有雷氏综合征，同型血尿症，酪氨酸血症，非酮糖症以及鸟氨酸转氨酶症等代谢病儿童的血浆中的含量会明显升高。
T38275	Kirromycin	Others	Others
	Kirromycin is an antibiotic originally isolated from Streptomyces and an inhibitor of protein biosynthesis. It inhibits isoleucine incorporation, polyphenylalanine synthesis, and growth of B. brevis. Kirromycin inhibits elongation factor Tu-dependent peptidyl transfer activity in E. coli.

天然产物

Cat.No: T0063

Synonym: 异亮氨酸,isoleucine,Ile,L-异亮氨酸

Target: Amino Acids and Derivatives, Endogenous Metabolite

Cat.No: T9143

Synonym: (2R,3R)-2-Amino-3-methylpentanoic acid,D-异亮氨酸,(R)-Isoleucine

Target: Others

L-Alloisoleucine

Cat.No: T5219

Synonym: L-别异亮氨酸,L-allo-Isoleucine,(3R)-LS-Isoleucine,L(+)-Alloisoleucine

Target: Others, Endogenous Metabolite

4-Hydroxyisoleucine

Cat.No: T7448

Synonym: 4-羟基-L-异亮氨酸,4-Hydroxy-L-isoleucine

Target: Others

(2S,3R,4S)-4-Hydroxyisoleucine

Cat.No: T2P2919

Synonym: (4S)-4-Hydroxy-L-isoleucine,(4S)4-羟基异亮氨酸,Hydroxyisoleucine

Target: PI3K

Methyl acetylacetate

Cat.No: T4851

Synonym: Methyl acetoacetate,乙酰乙酸甲酯

Target: Others, Endogenous Metabolite

L-Aspartic acid

Cat.No: T2O2731

Synonym: L-天冬氨酸,L-天冬氨酸；L-天冬碱;L-酰胺天冬酸；L-天冬酰胺一水物,Aspatofort,Asparagic acid

Target: Others, Endogenous Metabolite

Cat.No: T5306

Synonym: L-2-氨基丁酸,L-Aminobutyric Acid,L-α-amino-n-Butyric acid,L(+)-2-Aminobutyric acid

Target: Others, Endogenous Metabolite

Cat.No: T38275

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-02741	IARS1 Protein, Mouse, Recombinant (His & Myc) Isoleucyl-tRNA synthetase,Iars1,Isoleucine--tRNA li...	Mouse	E. coli
	Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. IARS1 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 16.8 kDa and the accession number is Q8BU30.
TMPH-01565	IARS Protein, Human, Recombinant (His & Myc) Isoleucine--tRNA ligase, cytoplasmic,Isoleucyl-tRNA...	Human	E. coli
	Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.
TMPH-01696	SLC16A4 Protein, Human, Recombinant (His) SLC16A4,Monocarboxylate transporter 5,Solute carrier family ...	Human	E. coli
	Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. SLC16A4 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 17.7 kDa and the accession number is O15374.
TMPH-02554	BCAT2 Protein, Mouse, Recombinant (His & Myc) Bcat2,BCAT(m),Eca40,Branched-chain-amino-acid aminotransfera...	Mouse	E. coli
	Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acids. BCAT2 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 48.2 kDa and the accession number is O35855.

重组蛋白

IARS1 Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02741

Species: Mouse

Expression System: E. coli

IARS Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01565

Species: Human

Expression System: E. coli

SLC16A4 Protein, Human, Recombinant (His)

Cat.No: TMPH-01696

Species: Human

Expression System: E. coli

BCAT2 Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02554

Species: Mouse

Expression System: E. coli

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