Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01551 |
IFNLR1 Protein, Human, Recombinant (His & SUMO)
Cytokine receptor class-II member 12,Likely int... |
Human | E. coli |
The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state. Determines the cell type specificity of the lambda interferon action. Shows a more restricted pattern of expression in the epithelial tissues thereby limiting responses to lambda interferons primar... |