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Search Results for " integrin "

Targets Recommended: Integrin Integrin

156

抑制剂 & 化合物

9

天然产物

92

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
TP1484L	α2β1 Integrin Ligand Peptide acetate α2β1 Integrin Ligand Peptide acetate (134580-64-6)	Integrin	Cytoskeletal Signaling
	α2β1 Integrin Ligand Peptide acetate (α2β1 Integrin Ligand Peptide acetate (134580-64-6)) 是 α2β1 整合素受体的潜在拮抗剂。它与细胞膜上的 α2β1 整合素受体相互作用，介导细胞外信号进入细胞。
T13473	αvβ1 integrin-IN-1	Integrin	Cytoskeletal Signaling
	αvβ1 integrin-IN-1是一种强效且具有选择性的αvβ1整合素抑制剂（IC50为0.63 nM），具有抗纤维化作用。
T40361	Integrin Binding Peptide
	Integrin Binding Peptide, derived from fibronectin, holds the potential as an essential component for preparing PEG hydrogels.
T36291	Integrin modulator 1	Others	Others
	Integrin modulator 1 is a potent and selective α4β1 integrin agonist, with an IC50 of 9.8 nM for RGD-binding α4β1. Integrin modulator 1 increases cell adhesion mediated by α4β1 integrin, with an EC50 of 12.9 nM[1]. Integrin modulator 1 (2-10 μg/mL; 30 min) significantly increases Jurkat E6.1 cell adhesion[1].Integrin modulator 1 (1-100 nM; 1 h) strongly and significantly increases ERK1/2 phosphorylation in Jurkat E6.1 cells[1].Integrin modulator 1 (1 nM-10 μM; 30 min) significantly increases the...
T40243	αvβ5 integrin-IN-1	Others	Others
	αvβ5 integrin-IN-1 is a first potent and selective αvβ5 integrin inhibitor (p IC 50 = 8.2) .
TP1484	α2β1 Integrin Ligand Peptide
	The Asp-Gly-Glu-Ala (DGEA) amino acid domain of type I collagen interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular signals into cells. It is a potential antagonist of collagen receptors.
T11663	Integrin-IN-2	Others	Others
	Integrin-IN-2 is an orally bioavailable pan αv integrin inhibitor.Integrin-IN-2 can increases the αvβ6, αvβ3, αvβ5 and αvβ8 binding affinities with pIC50 values of 7.8, 8.4, 8.4 and 7.4, respectively.
T15584	Integrin Antagonists 27	Others	Others
	Integrin Antagonists 27 is a small molecule integrin αvβ3 antagonist. It has a binding affinity of 18 nM and as a novel anticancer agent.
T13473L	αvβ1 integrin-IN-1 TFA (1689540-62-2 free base) αvβ1 integrin-IN-1 TFA	Integrin	Cytoskeletal Signaling
	αvβ1 integrin-IN-1 TFA 是一种有效的αvβ1整合素抑制剂(IC50: 0.63 nM)。
TP1374	α2β1 Integrin Ligand Peptide TFA
	α2β1 Integrin Ligand Peptide TFA interacts with the integrin receptor on the cell membrane and enters the cell to mediate extracellular signaling.It is a potential antagonist of the collagen receptor.
T16695	Pyrintegrin	Integrin	Cytoskeletal Signaling
	Pyrintegrin 是一种 β1 整合素激动剂，也是 2,4-二取代的嘧啶，可促进胚胎干细胞存活。它可用作足细胞保护剂，能增强细胞-细胞外基质 (ECM) 粘附介导的整联蛋白信号传导，具有强大的成脂作用。
T12177	Natalizumab	Integrin	Cytoskeletal Signaling
	Natalizumab 是重组人源化单克隆抗体，与 α4β1-整联蛋白结合并阻断其与血管细胞粘附分子 1 的相互作用。它也可阻止淋巴细胞进入中枢神经系统，从而防止急性脱髓鞘复发，可用于复发缓解型多发性硬化症和克罗恩氏病的研究。
TP1330	Cyclo(RADfK)	Integrin	Cytoskeletal Signaling
	Cyclo(RADfK) 是选择性 α(v)β(3) 整合素配体，广泛用于新血管生成的研究、治疗和诊断。它是 cyclo (-RGDfK-) 的阴性对照， RGD 肽。 RGD 肽是细胞粘附的调节剂，并被整合素家族的几个成员识别。
T6657	SB273005	Integrin	Cytoskeletal Signaling
	SB273005 是一种具有口服活性和高效性非肽整合素αvβ3 拮抗剂，抑制 αvβ3 和 αvβ5，可减少怀孕小鼠中 Th2 细胞和细胞因子 IL-10 的产生。
T6812	Cyclo(-RGDfK) Cyclo (-RGDfK)	Integrin	Cytoskeletal Signaling
	Cyclo(-RGDfK) (Cyclo (-RGDfK)) 是一种选择性整合素αvβ3的有效抑制剂，IC50值为 0.94 nM。它通过与细胞表面的 αvβ3 整合素结合，特异性靶向肿瘤微血管和癌细胞。
T6812L	Cyclo(-RGDfK) TFA	Integrin	Cytoskeletal Signaling
	Cyclo(-RGDfK) TFA 是一种选择性整合素αvβ3的有效抑制剂，其IC50值为 0.94 nM。它通过与细胞表面的 αvβ3 整合素结合，特异性靶向肿瘤微血管和癌细胞。
T82063	Integrin signaling inhibitor, mP13
	Integrinsignaling inhibitor, mP13 是抑制整合素信号传导，阻止内向外和外向内信号传递，涉及纤维蛋白原结合、血小板粘附及凝块收缩的化合物。
T79140	αvβ6 integrin inhibitor 2	Integrin	Cytoskeletal Signaling
	αvβ6integrin inhibitor 2 是一种高效的αvβ6整联蛋白抑制剂，具有96.5 nM的半抑制浓度（IC50）。
T79792	αvβ1 integrin-IN-2	Integrin	Cytoskeletal Signaling
	αvβ1integrin-IN-2（compound 32）作为整合素ανβ1与α5β1的抑制剂，展现出高效性，其IC50值分别为0.9 nM和33 nM。此外，该化合物对其他整合素亦有抑制作用，其IC50分别为380 nM（ανβ3）、280 nM（ανβ5）、230 nM（ανβ6）、87 nM（ανβ8）。
T79918	α7β1 integrin modulator-1	Integrin	Cytoskeletal Signaling
	α7β1integrinmodulator-1，作为一种高效的α7β1integrin调节剂，展现出在肌营养不良症研究中的应用潜力。
T63868	α5β1 integrin agonist-1	Others	Others
	α5β1 integrin agonist-1 是一种 α5β1 integrin 激动剂，可选择性地将 5-FU 输送到肿瘤细胞中，诱导肿瘤细胞死亡。
TP1204	iRGD peptide c(CRGDKGPDC)	Integrin	Cytoskeletal Signaling
	iRGD peptide (c(CRGDKGPDC)) 是由 9 个氨基酸组成的环肽，具有靶向肿瘤和肿瘤渗透的作用。
T7261	Grp94 Inhibitor-1	GPR; HSP	Cytoskeletal Signaling; Endocrinology/Hormones; GPCR/G Protein; Metabolism
	Grp94 Inhibitor-1 是一种选择性有效的 Grp94抑制剂，IC50值为 2 nM，是比 Hsp90α 的 1000 倍。
T4259	GLPG0187	Integrin	Cytoskeletal Signaling
	GLPG0187是整联蛋白受体的广谱拮抗剂，抑制αvβ1-integrin 的IC50值为1.3 nM，具有抗肿瘤活性。
T8523	ILK-IN-3	Integrin	Cytoskeletal Signaling
	ILK-IN-3 是一种整合素连接激酶抑制剂，具有抗肿瘤活性。
T13147	ICAM-1-IN-1	Integrin	Cytoskeletal Signaling
	ICAM-1-IN-1 是选择性的 ICAM-1和 E-selectin 抑制剂，IC50值分别为5和7 nM。
T73625	αvβ1 integrin-IN-1 TFA	Others	Others
	αvβ1integrin-IN-1 TFA (Compound C8) 为高效的αvβ1整合素选择性抑制剂，IC50值仅为0.63 nM，具备显著的抗纤维化能力。
T21868	BIO-1211	Integrin	Cytoskeletal Signaling
	BIO-1211 是高度选择性的、口服有效的α4β1 (VLA-4)抑制剂，对 α4β1 和 α4β7 的 IC50分别为 4 nM 和 2 μM。
TQ0250	CWHM-12	Integrin	Cytoskeletal Signaling
	CWHM-12 是 αV 整合素的有效抑制剂，抑制αvβ8、αvβ3、αvβ6和αvβ1，IC50 为 0.2、0.8、1.5 和 1.8 nM。
T6813	Cyclo(RGDyK) trifluoroacetate Cyclo(RGDyK)	Integrin	Cytoskeletal Signaling
	Cyclo(RGDyK) trifluoroacetate 是一种选择性αVβ3整联蛋白抑制剂，IC50为 20 nM。
T5488	ILK-IN-2 OSU-T315	Integrin	Cytoskeletal Signaling
	ILK-IN-2 (OSU-T315) 是一种新型强效口服活性的整合素连接激酶（ILK）抑制剂，IC50 为 0.6 μM。
T21781	A-286982	Integrin	Cytoskeletal Signaling
	A 286982是高效的LFA-1/ICAM-1相互作用变构抑制剂，在LFA-1/ICAM-1结合和LFA-1介导的细胞粘附实验中，其IC50分别为44和35 nM。
T12783	RWJ 50271	Integrin	Cytoskeletal Signaling
	RWJ 50271 是具有口服活性的选择性LFA-1/ICAM-1相互作用抑制剂，抑制 LFA-1/ICAM-1 介导的细胞粘附，在细胞HL60中的IC50值为 5.0 μM。
T2254	A-205804	Integrin	Cytoskeletal Signaling
	A-205804 是一种选择性口服有效的先导抑制剂，抑制 E-selectin 和 ICAM-1表达，IC50分别为 20 nM 和 25 nM，可用于慢性炎症疾病的研究。
TP1474	LXW7	Integrin	Cytoskeletal Signaling
	LXW7 是一种整合素αvβ3抑制剂，是含 Arg-Gly-Asp (RGD) 的环状肽，对αvβ3整联蛋白具有很高的结合亲和力，IC50为 0.68 μM。它可增强 VEGFR-2 磷酸化和 ERK1/2 活化，具有抗炎活性。
T2494	Cilengitide 西仑吉肽,EMD 121974	Integrin; Autophagy	Autophagy; Cytoskeletal Signaling
	Cilengitide (EMD 121974) 是一种有效的 αvβ3/5 受体整合素抑制剂，可抑制 ανβ3和 ανβ5与玻连蛋白结合，IC50值分别为 4 和 79 nM。
T3638	Leukadherin-1	Integrin; Complement System	Cytoskeletal Signaling; Immunology/Inflammation
	Leukadherin-1 是 CD11b/CD18 的变构激活剂，可增加 CD11b/CD18 依赖性细胞对纤维蛋白原的粘附，减少白细胞运动和跨内皮迁移，具有抗炎作用。
T5310	TR-14035 MDK-1191	Integrin	Cytoskeletal Signaling
	TR-14035 (MDK-1191) 是一种具有口服活性的 α4β7/α4β1整合素双重抑制剂，对 α4β7和 α4β1作用的 IC50值分别为 7 和 87 nM，可用于炎症和自体免疫疾病的研究。
T4400	DIM-C-pPhOH CDIM8	Apoptosis; Others	Apoptosis; Others
	DIM-C-pPhOH (CDIM8) 是一种核受体 4A1(NR4A1) 拮抗剂，可降低细胞增殖，对 ACHN 细胞和 786-O 细胞的IC50值分别为 13.6 μM 和 13.0 μM。它抑制癌细胞的生长和 mTOR 信号传导，诱导细胞凋亡和细胞应激。
T30751	Carotegrast methyl AJM300	Integrin	Cytoskeletal Signaling
	Carotegrast methyl (AJM300) 是一种口服有效和选择性 α4 整联蛋白拮抗剂，可预防小鼠结肠炎。HCA2969 是 Carotegrast methyl 的活性代谢产物，是一种特异的双重 α4β1/α4β7 整联蛋白拮抗剂。
T4435	E7820 ER68203-00	Integrin	Cytoskeletal Signaling
	E7820 (ER68203-00) 是具有口服活性芳香族磺酰胺衍生物，是一种血管生成抑制剂，可抑制内皮上整合素 α2 亚基的表达。它调节 α1，α2，α3 和 α5 整联素 mRNA 表达，具有抗血管生成和抗肿瘤活性。它抑制大鼠主动脉血管生成，IC50为 0.11 μg/ml。
T10397	ATN-161 trifluoroacetate salt ATN-161 TFA salt	Integrin	Cytoskeletal Signaling
	ATN-161 trifluoroacetate salt (ATN-161 TFA salt) 是一种新型整合素 α5β1 拮抗剂，可在小鼠模型中抑制血管生成和肝转移瘤的生长。
T6182	Tirofiban L700462,Aggrastat,替罗非班,MK383	Integrin	Cytoskeletal Signaling
	Tirofiban (L700462) 是一种非肽类选择性 GPIIb/IIIa 拮抗剂，IC50 为 9 nM，可抑制血小板聚集。
T6966	RGD RGD (Arg-Gly-Asp) Peptides,Arg-Gly-Asp,RGD Peptides	Integrin	Cytoskeletal Signaling
	RGD (RGD (Arg-Gly-Asp) Peptides) 是一种细胞粘附基序，可以模拟细胞粘附蛋白并与整合素结合。
T5485	OSU-T315 OSU-T315 (1,5-regioisomer),ILK-IN-2	Apoptosis; Integrin; Autophagy	Apoptosis; Autophagy; Cytoskeletal Signaling
	OSU-T315 (OSU-T315 (1,5-regioisomer)) 是一种整联蛋白连接激酶抑制剂，通过去磷酸化 AKT-Ser473 和其他 ILK 靶标抑制 PI3K/AKT 信号传导。它阻止 AKT 转位到脂筏消除 AKT 的活化，并以 ILK 非依赖性方式触发 Caspase 依赖性细胞凋亡。它通过自噬和凋亡导致细胞死亡。
T1950	PND-1186 PND1186,PND 1186,VS-4718,SR-2516	Apoptosis; FAK	Angiogenesis; Apoptosis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
	PND-1186 (VS-4718) 是一种高特异性的FAK 可逆抑制剂，IC50为 1.5 nM。它选择性促进肿瘤细胞凋亡。
T6806	Cilengitide TFA	Integrin; Autophagy	Autophagy; Cytoskeletal Signaling
	Cilengitide TFA 是一种选择性的 αvβ3和 αvβ5受体整合素抑制剂，IC50分别为 4 nM 和 79 nM。对 GP IIb/IIIa 的选择性约为 10 倍。
T3977	Lifitegrast SHP-606,SAR 1118,立他司特,利非司特	Integrin	Cytoskeletal Signaling
	Lifitegrast (SAR 1118) 是一种整合素淋巴细胞功能相关抗原 1 拮抗剂，抑制 Jurkat T 细胞附着于ICAM-1的IC50为 2.98 nM。
T7570	RGD peptide (GRGDNP) RGD peptide GRGDNP(2TFA),H-甘氨酰-精氨酰-甘氨酰-天冬氨酰-天冬酰胺酰-脯氨酸-OH,RGD peptide GRGDNP	Apoptosis; Integrin	Apoptosis; Cytoskeletal Signaling
	RGD peptide (GRGDNP) (RGD peptide GRGDNP(2TFA)) 是一种整合素-配体相互作用的抑制剂，通过激活构象变化促进细胞凋亡，从而增强 caspase-3的活化，在细胞黏附、迁移、生长和分化中发挥重要作用。
T2537	Tirofiban hydrochloride monohydrate Tirofiban Hydrochloride,盐酸替罗非班水合物,MK-383 Hydrochloride,盐酸替罗非班	ATPase; Integrin	Cytoskeletal Signaling; Membrane transporter/Ion channel
	Tirofiban hydrochloride monohydrate (MK-383 Hydrochloride) 是一种非肽类糖蛋白IIb/IIIa 的拮抗剂。

化合物

α2β1 Integrin Ligand Peptide acetate

Cat.No: TP1484L

Synonym: α2β1 Integrin Ligand Peptide acetate (134580-64-6)

Target: Integrin

αvβ1 integrin-IN-1

Cat.No: T13473

Target: Integrin

Integrin Binding Peptide

Cat.No: T40361

Integrin modulator 1

Cat.No: T36291

Target: Others

αvβ5 integrin-IN-1

Cat.No: T40243

Target: Others

α2β1 Integrin Ligand Peptide

Cat.No: TP1484

Integrin-IN-2

Cat.No: T11663

Target: Others

Integrin Antagonists 27

Cat.No: T15584

Target: Others

αvβ1 integrin-IN-1 TFA (1689540-62-2 free base)

Cat.No: T13473L

Synonym: αvβ1 integrin-IN-1 TFA

Target: Integrin

α2β1 Integrin Ligand Peptide TFA

Cat.No: TP1374

Cat.No: T16695

Target: Integrin

Cat.No: T12177

Target: Integrin

Cat.No: TP1330

Target: Integrin

Cat.No: T6657

Target: Integrin

Cat.No: T6812

Synonym: Cyclo (-RGDfK)

Target: Integrin

Cyclo(-RGDfK) TFA

Cat.No: T6812L

Target: Integrin

Integrin signaling inhibitor, mP13

Cat.No: T82063

αvβ6 integrin inhibitor 2

Cat.No: T79140

Target: Integrin

αvβ1 integrin-IN-2

Cat.No: T79792

Target: Integrin

α7β1 integrin modulator-1

Cat.No: T79918

Target: Integrin

α5β1 integrin agonist-1

Cat.No: T63868

Target: Others

Cat.No: TP1204

Synonym: c(CRGDKGPDC)

Target: Integrin

Grp94 Inhibitor-1

Cat.No: T7261

Target: GPR, HSP

Cat.No: T4259

Target: Integrin

Cat.No: T8523

Target: Integrin

Cat.No: T13147

Target: Integrin

αvβ1 integrin-IN-1 TFA

Cat.No: T73625

Target: Others

Cat.No: T21868

Target: Integrin

Cat.No: TQ0250

Target: Integrin

Cyclo(RGDyK) trifluoroacetate

Cat.No: T6813

Synonym: Cyclo(RGDyK)

Target: Integrin

Cat.No: T5488

Synonym: OSU-T315

Target: Integrin

Cat.No: T21781

Target: Integrin

Cat.No: T12783

Target: Integrin

Cat.No: T2254

Target: Integrin

Cat.No: TP1474

Target: Integrin

Cat.No: T2494

Synonym: 西仑吉肽,EMD 121974

Target: Integrin, Autophagy

Cat.No: T3638

Target: Integrin, Complement System

Cat.No: T5310

Synonym: MDK-1191

Target: Integrin

Cat.No: T4400

Synonym: CDIM8

Target: Apoptosis, Others

Carotegrast methyl

Cat.No: T30751

Synonym: AJM300

Target: Integrin

Cat.No: T4435

Synonym: ER68203-00

Target: Integrin

ATN-161 trifluoroacetate salt

Cat.No: T10397

Synonym: ATN-161 TFA salt

Target: Integrin

Cat.No: T6182

Synonym: L700462,Aggrastat,替罗非班,MK383

Target: Integrin

Cat.No: T6966

Synonym: RGD (Arg-Gly-Asp) Peptides,Arg-Gly-Asp,RGD Peptides

Target: Integrin

Cat.No: T5485

Synonym: OSU-T315 (1,5-regioisomer),ILK-IN-2

Target: Apoptosis, Integrin, Autophagy

Cat.No: T1950

Synonym: PND1186,PND 1186,VS-4718,SR-2516

Target: Apoptosis, FAK

Cilengitide TFA

Cat.No: T6806

Target: Integrin, Autophagy

Cat.No: T3977

Synonym: SHP-606,SAR 1118,立他司特,利非司特

Target: Integrin

RGD peptide (GRGDNP)

Cat.No: T7570

Synonym: RGD peptide GRGDNP(2TFA),H-甘氨酰-精氨酰-甘氨酰-天冬氨酰-天冬酰胺酰-脯氨酸-OH,RGD peptide GRGDNP

Target: Apoptosis, Integrin

Tirofiban hydrochloride monohydrate

Cat.No: T2537

Synonym: Tirofiban Hydrochloride,盐酸替罗非班水合物,MK-383 Hydrochloride,盐酸替罗非班

Target: ATPase, Integrin

Cat. No.	Product Name	Target	Signaling Pathways
T3862	Irigenin	NF-κB; Integrin	Cytoskeletal Signaling; NF-κB
	Irigenin 可通过特异性和选择性地阻断 Extra Domain A 域的 C-C 环上α9β1和α4β1整合素结合位点，介导其抗转移作用。可通过增强胃癌细胞中促凋亡分子的表达来敏化 TRAIL 诱导的凋亡，具有抗癌作用。
T3404	Cucurbitacin B Cuc B,葫芦素B,DATISCACIN,葫芦素 B,Amarine	Apoptosis; PTEN; Integrin; Endogenous Metabolite; HIF; STAT; Autophagy	Angiogenesis; Apoptosis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling; JAK/STAT signaling; Metabolism; PI3K/Akt/mTOR signaling; Stem Cells
	Cucurbitacin B (Cuc B) 是一具有抗癌活性的天然产物。
T36715	Tetrac Tetraiodothyroacetic acid,3,3',5,5'-Tetraiodothyroacetic acid	Apoptosis; EGFR	Angiogenesis; Apoptosis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Tetrac (Tetraiodothyroacetic acid)是L-甲状腺素(T4)的衍生物，是一种甲状腺整合素受体拮抗剂。Tetrac通过阻断EGFR介导的结直肠癌细胞信号传导来诱导抗增殖。Tetrac 可阻断 T4 和 3,5,3'-triiodo-L-thyronine (T3)在细胞表面甲状腺素整合素 αvβ3 受体上的作用。Tetra 具有抗血管生成、抗肿瘤活性和促凋亡活性。
T3834	8-Epideoxyloganic acid 8-表去氧马钱酸	ROS; Immunology/Inflammation related	Immunology/Inflammation
	8-Epideoxyloganic acid 是从 Incarvillea delavayi 中分离得到的一种环烯醚萜苷。它具有微弱的缓解疼痛活性。
T4S0498	Glaucocalyxin A 蓝萼甲素,Wangzaozin B,Leukamenin F	Apoptosis; Akt; Caspase; PI3K	Apoptosis; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Glaucocalyxin A (Leukamenin F) 是来自日本黑纹病菌的一种对映型月桂基二萜，具有抗肿瘤作用。它通过调节PI3K/Akt 信号通路抑制 GLI1 的核易位，诱导骨肉瘤凋亡。
T5S0055	Chelidonine Helidonine,Khelidonin,白屈菜碱,Stylophorin	Apoptosis; Others; Influenza Virus	Apoptosis; Microbiology/Virology; Others
	Chelidonine (Stylophorin) 是白屈菜中的一种异喹啉生物碱，有抗肿瘤和抗病毒作用。它可导致细胞周期 G2/M 停滞，诱导 caspase 依赖和非依赖性的细胞凋亡。
TN5447	Apigenin 7-O-methylglucuronide 芹菜素-7-O-β-D-葡萄糖醛酸甲酯,Apigenin-7-O-β-D-glucuronide methyl ester
	Apigenin 7-O-methylglucuronide did not affect GAG level or secretion, may potentially be used in osteogenesis imperfecta (OI) type I pharmacotherapy in patients with normal GAG content. Apigenin 7-O-methylglucuronide which normalized collagen synthesis in
T40960	Fibronectin	Integrin	Cytoskeletal Signaling
	Fibronectin 是存在于血液、结缔组织和细胞表面中的高分子糖蛋白，可作为组织损伤的生物标记物。Fibronectin 可被整合素家族表面受体识别。Fibronectin 可用于研究原发性开角型青光眼。
T36295	Echistatin TFA	Others	Others
	Echistatin TFA, the smallest active RGD protein belonging to the family of disintegrins that are derived from snake venoms, is a potent inhibitor of platelet aggregation. Echistatin is a potent inhibitor of bone resorption in culture. Echistatin is a potent antagonist of αIIbβ3, αvβ3 and α5β1[1][2][3][4]. [1]. J Musial, et al. Inhibition of platelet adhesion to surfaces of extracorporeal circuits by disintegrins. RGD-containing peptides from viper venoms. Circulation. 1990 Jul;82(1):261-73.[2]. ...

天然产物

Cat.No: T3862

Target: NF-κB, Integrin

Cat.No: T3404

Synonym: Cuc B,葫芦素B,DATISCACIN,葫芦素 B,Amarine

Target: Apoptosis, PTEN, Integrin, Endogenous Metabolite, HIF, STAT, Autophagy

Cat.No: T36715

Synonym: Tetraiodothyroacetic acid,3,3',5,5'-Tetraiodothyroacetic acid

Target: Apoptosis, EGFR

8-Epideoxyloganic acid

Cat.No: T3834

Synonym: 8-表去氧马钱酸

Target: ROS, Immunology/Inflammation related

Glaucocalyxin A

Cat.No: T4S0498

Synonym: 蓝萼甲素,Wangzaozin B,Leukamenin F

Target: Apoptosis, Akt, Caspase, PI3K

Cat.No: T5S0055

Synonym: Helidonine,Khelidonin,白屈菜碱,Stylophorin

Target: Apoptosis, Others, Influenza Virus

Apigenin 7-O-methylglucuronide

Cat.No: TN5447

Synonym: 芹菜素-7-O-β-D-葡萄糖醛酸甲酯,Apigenin-7-O-β-D-glucuronide methyl ester

Cat.No: T40960

Target: Integrin

Cat.No: T36295

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-03878	Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) Integrin alpha V β6,ITGAV & ITGB6,integrin...	Human	HEK293 Cells
	Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1.
TMPY-05717	Integrin alpha V beta 8 Protein, Human, Recombinant (His) Integrin alpha V β8,Integrin α V β 8	Human	HEK293 Cells
	Integrin alpha V beta 8 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. ITGAVB8 does not appear to assume different activation states; and the cytoplasmic tail does not connect to the cytoskeleton. It binds ligands containing an RGD motif; including vitronectin; fibrin and the latency associated peptide (LAP) of the latent TGF-beta complex. High affinity binding of alpha V beta 8 to LAP allows proteolytic cleavage by MT1-MMP; which releases active TGF-beta. This m...
TMPY-04643	Integrin alpha V beta 6 Protein, Mouse, Recombinant (Flag & His) integrin, α5 (fibronectin receptor, α polypeptide),...	Mouse	HEK293 Cells
	Integrin alpha V beta 6 Protein, Mouse, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is NP_032428.2&NP_067334.1.
TMPY-05716	Integrin alpha V beta 3 Protein, Human, Recombinant (His) Integrin α V β 3,Integrin alpha V β3	Human	HEK293 Cells
	Integrin alpha-V & beta-3 (ITGAV/ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor.
TMPY-02159	Integrin alpha 5 beta 1 Protein, Human, Recombinant (Flag & His) Integrin alpha 5 β1,Integrin α5 β 1,in...	Human	HEK293 Cells
	Integrin alpha 5 beta 1 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 192 kDa and the accession number is P08648&P05556-1.
TMPY-02158	Integrin alpha 6 beta 1 Protein, Human, Recombinant (Flag & His) Integrin α6 β 1,ITGA6B,VLA-6,integrin, α6,...	Human	HEK293 Cells
	Integrin alpha 6 beta 1 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 198 kDa and the accession number is P23229-3&P05556-1.
TMPY-02160	Integrin alpha 8 beta 1 Protein, Human, Recombinant (Flag & His) Integrin α8 β 1,integrin, α8,integrin<...	Human	HEK293 Cells
	Integrin alpha 8 beta 1 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 196 kDa and the accession number is P53708&P05556-1.
TMPY-04881	Integrin alpha 6 beta 4 Protein, Human, Recombinant (Flag & His) Integrin alpha 6 β4,Integrin α6 β 4	Human	HEK293 Cells
	Integrin alpha 6 beta 4 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 196 kDa and the accession number is CAA37656.1.
TMPY-05762	Integrin alpha X beta 2 Protein, Human, Recombinant (His) Integrin α X β 2,integrin, alpha X (comple...	Human	HEK293 Cells
	Integrin alpha X beta 2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 204.8 kDa and the accession number is P20702&P05107.
TMPY-00476	ITGB1 Protein, Human, Recombinant (His) VLAB,integrin, beta 1 (fibronectin receptor, beta p...	Human	HEK293 Cells
	ITGB1 (Integrin Subunit Beta 1) is a Protein Coding gene. This gene encodes a beta subunit, which is a type 1 transmembrane protein of the integrin beta chain family. ITGB1 is a heterodimeric cell-surface receptor involved in cell functions such as proliferation, migration, invasion, and survival. ITGB1 has been recognized to play a major role in tumor growth, invasion, and metastasis. Using luciferase assays, the researcher identified ITGB1 as a direct target of miR-134. ITGB1 is a direct targe...
TMPY-02161	Integrin alpha X beta 2 Protein, Human, Recombinant (Flag & His) integrin, α X (complement component 3 receptor 4 su...	Human	HEK293 Cells
	Integrin alpha X beta 2 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 205 kDa and the accession number is P20702&P05107.
TMPJ-00211	CD47 Protein, Human, Recombinant (His) MER6,Integrin-Associated Protein,Leukocyte Surface ...	Human	HEK293 Cells
	CD47 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 30-45 KDa and the accession number is Q08722.
TMPK-00839	ITGB6 Protein, Human, Recombinant (His) β6,Integrin β-6,β 6,beta 6,Integrin β 6,	Human	HEK293 Cells
	ITGB6 is known to be one of the major receptor components involved in host tropism of foot-and-mouth disease (FMD) virus in cattle. A competitive PCR technique called ARMS PCR was adapted to identify a single-nucleotide polymorphism (SNP), G29A, db SNP Id: rs109075046, in the 5' untranslated region (5'UTR) of the bovine ITGB6 gene. ITGB6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 75.4 kDa and the accession number is ...
TMPK-01247	ITGB6 Protein, Mouse, Recombinant (His) ITGB6,Integrin β-6,Integrin beta-6	Mouse	HEK293 Cells
	ITGB6 is known to be one of the major receptor components involved in host tropism of foot-and-mouth disease (FMD) virus in cattle. A competitive PCR technique called ARMS PCR was adapted to identify a single-nucleotide polymorphism (SNP), G29A, db SNP Id: rs109075046, in the 5' untranslated region (5'UTR) of the bovine ITGB6 gene. ITGB6 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 75.7 kDa and the accession number is ...
TMPJ-00810	ITGA5 Protein, Human, Recombinant (His) FNRA,Integrin α-5,Integrin Alpha-F,Fibrone...	Human	HEK293 Cells
	Integrin α-5 belongs to the Integrin α chain family and contains 7 FG-GAP repeats. Integrin α-5 joins with Integrin-β1 to form a fibronectin and laminin receptor which recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. It is expressed on fibroblasts, endothelial cells, peripheral T cells and platelets. Integrin α-5 undergoes post-translational cleavage in the ext...
TMPH-03206	ITGB8 Protein, Rabbit, Recombinant (His & Myc) ITGB8,Integrin beta-8	Rabbit	E. coli
	Integrin alpha-V:beta-8 (ITGAV:ITGB8) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation on the surface of activated regulatory T-cells (Tregs). Required during vasculogenesis. ITGB8 Protein, Rabbit, Recombinant (His & Myc) is expressed in E. coli ...
TMPH-01536	ITGB4 Protein, Human, Recombinant (His & Myc) GP150,ITGB4,Integrin beta-4	Human	E. coli
	Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling. ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling.
TMPH-01538	ITGBL1 Protein, Human, Recombinant (His & Myc) ITGBL1,Osteoblast-specific cysteine-rich protein,Integri...	Human	E. coli
	ITGBL1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
TMPH-01537	ITGB7 Protein, Human, Recombinant (His) Integrin beta-7,ITGB7,Gut homing receptor beta subu...	Human	E. coli
	ITGB7 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 82.5 kDa and the accession number is P26010.
TMPY-02289	CIB2 Protein, Human, Recombinant (His) DFNB48,calcium and integrin binding family member 2...	Human	E. coli
	Calcium and integrin-binding protein 2 (CIB2) belongs to a protein family with four known members, CIB1 through CIB4, which are characterized by multiple calcium-binding EF-hand domains. Sensorineural hearing loss is genetically heterogeneous. The mutations in CIB2, which encodes a calcium- and integrin-binding protein, are associated with nonsyndromic deafness (DFNB48) and Usher syndrome type 1J (USH1J). Furthermore, in zebrafish and Drosophila melanogaster, CIB2 is essential for the function a...
TMPH-01539	ILK Protein, Human, Recombinant (His) ILK-1,ILK,Integrin-linked protein kinase,59 kDa ser...	Human	Baculovirus Insect Cells
	Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Regulates cell motility by forming a complex with PARVB. P...
TMPJ-00786	ITGB1 Protein, Human, Recombinant (aa 21-728, His) Integrin Beta-1,VLA-4 Subunit β,Fibronectin Recepto...	Human	HEK293 Cells
	Integrin β-1 (ITGB1) belongs to the integrin β chain family. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. ITGB1 is an integrin unit associated with very late antigen receptors, which contains one VWFA domain. It is known to conjoin with α-3 subunit to create α3β1 complex that reacts to such molecules as netrin-1 and ree...
TMPH-03114	ITGB1 Protein, Pig, Recombinant (His & Myc) VLA-4 subunit beta,Integrin beta-1,Fibronectin rece...	Sus scrofa (Pig)	E. coli
	ITGB1 Protein, Pig, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 34.1 kDa and the accession number is Q9GLP0.
TMPY-02198	ILKAP Protein, Human, Recombinant (His) ILKAP3,PP2C-δ,PP2C-DELTA,integrin-linked kinase-ass...	Human	HEK293 Cells
	Integrin-linked kinase-associated serine/threonine phosphatase 2C, also known as ILKAP, is a cytoplasm protein that belongs to the PP2C family. ILKAP contains one PP2C-like domain. ILKAP is widely expressed. Highest levels expressed in striated muscle. Much lower levels are evident in various smooth muscle tissues. ILKAP may play a role in the regulation of cell cycle progression via dephosphorylation of its substrates whose appropriate phosphorylation states might be crucial for cell proliferat...
TMPJ-00212	CD47 Protein, Human, Recombinant (mFc) CD47,IAP,Integrin-associated protein,Antigenic surf...	Human	HEK293 Cells
	CD47 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 48-65 KDa and the accession number is Q08722.
TMPJ-00614	CD47 Protein, Rhesus macaque, Recombinant (His & Flag) MER6,Integrin-Associated Protein,IAP,Leukocyte Surf...	Rhesus	HEK293 Cells
	CD47, also known as Integrin‑Associated Protein (IAP) and OA3, is a glycosylated atypical member of the immunoglobulin superfamily. Mouse CD47 is an integral membrane protein that consists of a extracellular domain (ECD) with a single Ig‑like domain, five membrane-spanning regions with short intervening loops, and C‑terminal cytoplasmic tail. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It plays an important r...
TMPJ-00445	IBSP Protein, Mouse, Recombinant (His) BNSP,IBSP,Integrin binding sialoprotein,Cell bindin...	Mouse	HEK293 Cells
	Bone sialoprotein 2(IBSP) is a monomeric non‑collagenous member of the SIBLING family of extracellular matrix proteins. It is principally associated with the early stages of bone mineralization. Mouse IBSP is synthesized as a 324 amino acid (aa) precursor that contains a 16 aa signal sequence and a 308 aa mature region. The mature segment is divided into a basic N‑terminus (aa 17 ‑ 62), a central region (aa 63 ‑ 233), and an acidic C‑terminus (aa 234 ‑ 317). IBSP is highly glycosylated, sulfate...
TMPJ-00209	CD47 Protein, Human, Recombinant (Avi & His), Biotinylated Protein MER6,Integrin-Associated Protein,MER6,CD47,...	Human	HEK293 Cells
	CD47 Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 30-40 KDa and the accession number is Q08722.
TMPJ-00613	CD47 Protein, Rhesus macaque, Recombinant (hFc) Protein MER6,Integrin-Associated Protein,MER6,IAP,C...	Rhesus	HEK293 Cells
	CD47 Protein, Rhesus macaque, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60-90 KDa and the accession number is F7A802.
TMPJ-00208	CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated Protein MER6,MER6,IAP,CD47,Antigenic surface determinant pro...	Human	HEK293 Cells
	CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag. The predicted molecular weight is 60-70 KDa and the accession number is Q08722.
TMPH-02729	ITGAX Protein, Mouse, Recombinant (His & MBP) Leukocyte adhesion glycoprotein p150,95 alpha chain,CD11 ant...	Mouse	Baculovirus Insect Cells
	ITGAX Protein, Mouse, Recombinant (His & MBP) is expressed in Baculovirus.
TMPJ-00242	PARVA Protein, Human, Recombinant (His) PARVA,CH-ILKBP,Actopaxin,Alpha-Parvin,Matrix-Remodeling-Asso...	Human	E. coli
	Alpha-Parvin (PARVA) is a member of the Parvin family. PARVA contains two CH (calponin-homology) domains. PARVA is widely expressed, with highest levels in heart, skeletal muscle, kidney and liver. PARVA interacts with integrin-linked protein kinase and probably with actin and the LD1 and LD4 motifs of PXN. PARVA may play a role in the regulation of cell adhesion and cytoskeleton organization. PARVA is also involved in ciliogenesis.
TMPH-00213	Disintegrin batroxostatin Protein, Bothrops atrox, Recombinant (His & Myc) Platelet aggregation activation inhibitor,Disintegrin	Bothrops atrox	E. coli
	Inhibits fibrinogen interaction with platelets. Acts by binding to the glycoprotein IIb-IIIa receptor (ITGA2B/ITGB3) on the platelet surface and inhibits aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Also inhibits T24 and SK-Mel-28 cell adhesion to fibronectin with IC(50) of 4.4 uM and 33 nM, respectively. Disintegrin batroxostatin Protein, Bothrops atrox, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted...
TMPH-02569	WISP2/CCN5 Protein, Mouse, Recombinant (His) Ccn5,Connective tissue growth factor-like protein,CCN family...	Mouse	P. pastoris (Yeast)
	May play an important role in modulating bone turnover. Promotes the adhesion of osteoblast cells and inhibits the binding of fibrinogen to integrin receptors. In addition, inhibits osteocalcin production.
TMPH-03297	LGALS3BP Protein, Rat, Recombinant (His) Protein 90K,Mac-2-binding protein,Galectin-3-binding protein...	Rat	E. coli
	Promotes integrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells.
TMPY-02761	Rack1 Protein, Human, Recombinant (His & MBP) PIG21,Gnb2-rs1,H12.3,RACK1,HLC-7	Human	E. coli
	The scaffolding protein, Rack1, is a seven-WD-domain-containing protein that has been implicated in binding to integrin beta subunit cytoplasmic domains and to members of two kinase families (src and protein kinase C, PKC) that mediate integrin bidirectional signaling.Rack1 may link protein kinase C directly to integrins and participate in the regulation of integrin functions.Rack1 regulates the localization of an essential PCP protein and acts as a molecular switch to promote PCP signaling.
TMPH-01362	LGALS3BP Protein, Human, Recombinant (His) LGALS3BP,Lectin galactoside-binding soluble 3-binding protei...	Human	E. coli
	Promotes integrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells. LGALS3BP Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 67.4 kDa and the accession number is Q08380.
TMPJ-00352	CD98 Protein, Human, Recombinant (mFc) Lymphocyte activation antigen 4F2 large subunit,4F2 cell-sur...	Human	HEK293 Cells
	CD98 is a multifunctional glycoprotein that is involved in various biological processes such as amino acid transport, cell adhesion, diffusion, adhesion, and proliferation. CD98 can interact with CD147 to induce integrin 1 function to promote cyclosporine B-induced cell adhesion and p44/p42 MAPK activation following PI3K activation. CD98 heavy chain has been studied to be a key player in tumorigenesis due to its role in activating integrin signaling to promote tumor progression via angiogenesis,...
TMPH-03203	FGFb Protein, Rabbit, Recombinant (His & SUMO) Basic fibroblast growth factor,Fibroblast growth factor 2,FG...	Rabbit	E. coli
	Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation. FGFb Protein, Rabbit, Recombinant (His & SUMO) is expressed in E. coli exp...
TMPH-02570	WISP2/CCN5 Protein, Mouse, Recombinant (His & SUMO) CCN family member 5,Connective tissue growth factor-like pro...	Mouse	E. coli
	May play an important role in modulating bone turnover. Promotes the adhesion of osteoblast cells and inhibits the binding of fibrinogen to integrin receptors. In addition, inhibits osteocalcin production.
TMPK-00635	CDCP1 Protein, Rat, Recombinant (His) TRASK,SIMA135,UNQ2486,CD318,PRO5773,CDCP1	Rat	HEK293 Cells
	Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression. CDCP1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 73.09 kDa and the accession number is D3ZVA1.
TMPH-02731	ICAM4 Protein, Mouse, Recombinant (His & SUMO) Intercellular adhesion molecule 4,Icam4	Mouse	E. coli
	Adhesion molecule that binds to leukocyte adhesion LFA-1 protein LFA-1 (integrin alpha-L/beta-2). ICAM4 is also a ligand for alpha-4/beta-1 and alpha-V integrins. Isoform 2 may modulate binding of membrane-associated ICAM4. ICAM4 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 39.1 kDa and the accession number is Q9ERM2.
TMPK-01181	CDCP1 Protein, Human, Recombinant (His & Avi), Biotinylated CDCP1,PRO5773,TRASK,UNQ2486,SIMA135,CD318	Human	HEK293 Cells
	Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression. CDCP1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 74.6 kDa and the accession number is Q9...
TMPK-01010	CDCP1 Protein, Mouse, Recombinant (His & Avi), Biotinylated UNQ2486,TRASK,CD318,SIMA135,CDCP1,PRO5773	Mouse	HEK293 Cells
	Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression. CDCP1 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 75.3 kDa and the accession number is Q5...
TMPH-00368	FGF-2 Protein, Chicken, Recombinant (His) Heparin-binding growth factor 2,FGF2,Fibroblast growth facto...	Chicken	P. pastoris (Yeast)
	Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. FGF-2 Protein, Chicken, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 18.3 kDa and the accession number is P48800.
TMPH-00037	Leukotoxin Protein, Aggregatibacter actinomycetemcomitans, Recombinant (His) ltxA,Leukotoxin	Aggregatibacter actinomycetemcomitans	P. pastoris (Yeast)
	Virulence factor that plays an important role in immune evasion. Lyses human lymphocytes and monocytes. Binds to the LFA-1 integrin on the surface of the host cell and to cholesterol-containing membranes, which probably results in large LtxA-LFA-1 clusters in lipid rafts. Shows also beta-hemolytic activity on certain types of growth media. Leukotoxin Protein, Aggregatibacter actinomycetemcomitans, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 38.3 kD...
TMPH-00369	FGF-2 Protein, Chicken, Recombinant (His & Myc) Basic fibroblast growth factor,Fibroblast growth factor 2,He...	Chicken	E. coli
	Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. FGF-2 Protein, Chicken, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 23.8 kDa and the accession number is P48800.
TMPY-05291	CD57/B3gat1 Protein, Human, Recombinant (mFc) LEU7,NK1,beta-1,3-glucuronyltransferase 1,HNK1,GLCATP,NK-1,β...	Human	HEK293 Cells
	B3GAT1 is the key enzyme during the biosynthesis of the carbohydrate epitope HNK-1, which is present on a number of cell adhesion molecules important in neurodevelopment. Saturating concentrations of rVAR2 inhibited downstream integrin signaling, which was mimicked by knockdown of the core chondroitin sulfate synthesis enzymes β-1,3-glucuronyltransferase 1 (B3GAT1) and chondroitin sulfate N-acetylgalactosaminyltransferase 1 (CSGALNACT1).
TMPJ-00377	VCAM-1 Protein, Human, Recombinant (Avi & His), Biotinylated INCAM-100,Vascular cell adhesion protein 1,V-CAM 1,CD106,VCA...	Human	HEK293 Cells
	VCAM-1 (CD106, INCAM-110) is a cell adhesion molecule and a member of the immunoglobulin superfamily. It's important function is a recognition of cell-cell. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation。
TMPK-00837	Galectin-3 Protein, Human, Recombinant (His) LGALS2,GAL3,MAC2GAL3,Galectin3,L31,Mac-2,GALBPCBP35,GALIG,CB...	Human	HEK293 Cells
	Human Galectin-3, also known as Mac-2, L29, CBP35, and epsilon BP, is classified as a chimeric member of the Galectin superfamily and contains one carbohydrate recognition domain (CRD) linked to a nonlectin domain.Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity).
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重组蛋白

Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)

Cat.No: TMPY-03878

Species: Human

Expression System: HEK293 Cells

Integrin alpha V beta 8 Protein, Human, Recombinant (His)

Cat.No: TMPY-05717

Species: Human

Expression System: HEK293 Cells

Integrin alpha V beta 6 Protein, Mouse, Recombinant (Flag & His)

Cat.No: TMPY-04643

Species: Mouse

Expression System: HEK293 Cells

Integrin alpha V beta 3 Protein, Human, Recombinant (His)

Cat.No: TMPY-05716

Species: Human

Expression System: HEK293 Cells

Integrin alpha 5 beta 1 Protein, Human, Recombinant (Flag & His)

Cat.No: TMPY-02159

Species: Human

Expression System: HEK293 Cells

Integrin alpha 6 beta 1 Protein, Human, Recombinant (Flag & His)

Cat.No: TMPY-02158

Species: Human

Expression System: HEK293 Cells

Integrin alpha 8 beta 1 Protein, Human, Recombinant (Flag & His)

Cat.No: TMPY-02160

Species: Human

Expression System: HEK293 Cells

Integrin alpha 6 beta 4 Protein, Human, Recombinant (Flag & His)

Cat.No: TMPY-04881

Species: Human

Expression System: HEK293 Cells

Integrin alpha X beta 2 Protein, Human, Recombinant (His)

Cat.No: TMPY-05762

Species: Human

Expression System: HEK293 Cells

ITGB1 Protein, Human, Recombinant (His)

Cat.No: TMPY-00476

Species: Human

Expression System: HEK293 Cells

Integrin alpha X beta 2 Protein, Human, Recombinant (Flag & His)

Cat.No: TMPY-02161

Species: Human

Expression System: HEK293 Cells

CD47 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00211

Species: Human

Expression System: HEK293 Cells

ITGB6 Protein, Human, Recombinant (His)

Cat.No: TMPK-00839

Species: Human

Expression System: HEK293 Cells

ITGB6 Protein, Mouse, Recombinant (His)

Cat.No: TMPK-01247

Species: Mouse

Expression System: HEK293 Cells

ITGA5 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00810

Species: Human

Expression System: HEK293 Cells

ITGB8 Protein, Rabbit, Recombinant (His & Myc)

Cat.No: TMPH-03206

Species: Rabbit

Expression System: E. coli

ITGB4 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01536

Species: Human

Expression System: E. coli

ITGBL1 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01538

Species: Human

Expression System: E. coli

ITGB7 Protein, Human, Recombinant (His)

Cat.No: TMPH-01537

Species: Human

Expression System: E. coli

CIB2 Protein, Human, Recombinant (His)

Cat.No: TMPY-02289

Species: Human

Expression System: E. coli

ILK Protein, Human, Recombinant (His)

Cat.No: TMPH-01539

Species: Human

Expression System: Baculovirus Insect Cells

ITGB1 Protein, Human, Recombinant (aa 21-728, His)

Cat.No: TMPJ-00786

Species: Human

Expression System: HEK293 Cells

ITGB1 Protein, Pig, Recombinant (His & Myc)

Cat.No: TMPH-03114

Species: Sus scrofa (Pig)

Expression System: E. coli

ILKAP Protein, Human, Recombinant (His)

Cat.No: TMPY-02198

Species: Human

Expression System: HEK293 Cells

CD47 Protein, Human, Recombinant (mFc)

Cat.No: TMPJ-00212

Species: Human

Expression System: HEK293 Cells

CD47 Protein, Rhesus macaque, Recombinant (His & Flag)

Cat.No: TMPJ-00614

Species: Rhesus

Expression System: HEK293 Cells

IBSP Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00445

Species: Mouse

Expression System: HEK293 Cells

CD47 Protein, Human, Recombinant (Avi & His), Biotinylated

Cat.No: TMPJ-00209

Species: Human

Expression System: HEK293 Cells

CD47 Protein, Rhesus macaque, Recombinant (hFc)

Cat.No: TMPJ-00613

Species: Rhesus

Expression System: HEK293 Cells

CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated

Cat.No: TMPJ-00208

Species: Human

Expression System: HEK293 Cells

ITGAX Protein, Mouse, Recombinant (His & MBP)

Cat.No: TMPH-02729

Species: Mouse

Expression System: Baculovirus Insect Cells

PARVA Protein, Human, Recombinant (His)

Cat.No: TMPJ-00242

Species: Human

Expression System: E. coli

Disintegrin batroxostatin Protein, Bothrops atrox, Recombinant (His & Myc)

Cat.No: TMPH-00213

Species: Bothrops atrox

Expression System: E. coli

WISP2/CCN5 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02569

Species: Mouse

Expression System: P. pastoris (Yeast)

LGALS3BP Protein, Rat, Recombinant (His)

Cat.No: TMPH-03297

Species: Rat

Expression System: E. coli

Rack1 Protein, Human, Recombinant (His & MBP)

Cat.No: TMPY-02761

Species: Human

Expression System: E. coli

LGALS3BP Protein, Human, Recombinant (His)

Cat.No: TMPH-01362

Species: Human

Expression System: E. coli

CD98 Protein, Human, Recombinant (mFc)

Cat.No: TMPJ-00352

Species: Human

Expression System: HEK293 Cells

FGFb Protein, Rabbit, Recombinant (His & SUMO)

Cat.No: TMPH-03203

Species: Rabbit

Expression System: E. coli

WISP2/CCN5 Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02570

Species: Mouse

Expression System: E. coli

CDCP1 Protein, Rat, Recombinant (His)

Cat.No: TMPK-00635

Species: Rat

Expression System: HEK293 Cells

ICAM4 Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02731

Species: Mouse

Expression System: E. coli

CDCP1 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-01181

Species: Human

Expression System: HEK293 Cells

CDCP1 Protein, Mouse, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-01010

Species: Mouse

Expression System: HEK293 Cells

FGF-2 Protein, Chicken, Recombinant (His)

Cat.No: TMPH-00368

Species: Chicken

Expression System: P. pastoris (Yeast)

Leukotoxin Protein, Aggregatibacter actinomycetemcomitans, Recombinant (His)

Cat.No: TMPH-00037

Species: Aggregatibacter actinomycetemcomitans

Expression System: P. pastoris (Yeast)

FGF-2 Protein, Chicken, Recombinant (His & Myc)

Cat.No: TMPH-00369

Species: Chicken

Expression System: E. coli

CD57/B3gat1 Protein, Human, Recombinant (mFc)

Cat.No: TMPY-05291

Species: Human

Expression System: HEK293 Cells

VCAM-1 Protein, Human, Recombinant (Avi & His), Biotinylated

Cat.No: TMPJ-00377

Species: Human

Expression System: HEK293 Cells

Galectin-3 Protein, Human, Recombinant (His)

Cat.No: TMPK-00837

Species: Human

Expression System: HEK293 Cells

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