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TMPY-00395
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Insulin Protein, Human, Recombinant
IDDM1,MODY10,ILPR,IDDM2,IRDN,IDDM,insulin,INS
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Human
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P. pastoris (Yeast)
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INS (Insulin) is a Protein Coding gene. This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. The binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Diseases associated with ... |
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TMPY-01146
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Insulin Receptor Protein, Human, Recombinant (long isoform, His)
HHF5,CD220,insulin receptor
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Human
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HEK293 Cells
|
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Insulin Receptor Protein, Human, Recombinant (long isoform, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 107 kDa and the accession number is P06213-1. |
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TMPY-01149
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Insulin Receptor Protein, Human, Recombinant (short isoform, His)
Insulin Receptor,HHF5,CD220
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Human
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HEK293 Cells
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Insulin Receptor Protein, Human, Recombinant (short isoform, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 106 kDa and the accession number is P06213-2. |
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TMPY-04395
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Insulin Receptor Protein, Human, Recombinant (His & GST)
HHF5,insulin receptor,CD220
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Human
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Baculovirus Insect Cells
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Insulin Receptor Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 72.3 kDa and the accession number is P06213-1. |
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TMPY-05283
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Insulin Receptor Protein, Human, Recombinant (long isoform, His), Biotinylated
CD220,Insulin Receptor,HHF5
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Human
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HEK293 Cells
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Insulin Receptor Protein, Human, Recombinant (long isoform, His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 107 kDa and the accession number is P06213-1. |
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TMPK-01354
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IGF2R Protein, Human, Recombinant (His & Avi)
M6P/IGF2R,IGF-II receptor,MPRI,CI-MPR,CD222,MPR 300,M6PR
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Human
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HEK293 Cells
|
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The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer. IGF2R Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 164.90 kDa and the accession number is P11717. |
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TMPY-00545
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Dermcidin Protein, Human, Recombinant (hFc)
AIDD,PIF,HCAP,dermcidin,DCD-1,DSEP
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Human
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HEK293 Cells
|
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Hepatocellular carcinoma (HCC) is a major contributor to cancer-related deaths due to its often late stage diagnosis, and dermcidin (DCD) may have the potential to be used as a serum biomarker for HCC for more timely diagnoses. Human dermcidin (DCD) is an antimicrobial peptide secreted constitutively by sweat glands. And the role of DCD in ischemic heart disease has drawn increasing attention in particular its relationship with insulin secretion and glycemic control, nitric oxide (NO) synthesis ... |
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TMPY-03962
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AFM Protein, Human, Recombinant (His)
afamin,ALBA,ALB2,ALF
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Human
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HEK293 Cells
|
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Afamin is an 87 kDa glycoprotein with five predicted N-glycosylation sites. Afamin's glycan abundance contributes to conformational and chemical inhomogeneity presenting great challenges for molecular structure determination. Afamin, a human plasma glycoprotein and putative transporter of hydrophobic molecules, has been shown to act as extracellular chaperone for poorly soluble, acylated Wnt proteins, forming a stable, soluble complex with functioning Wnt proteins. The 2.1-Å crystal structure of... |
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TMPY-00150
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IGF2/IGF-II Protein, Human, Recombinant
PP9974,胰岛素样生长因子,C11orf43,IGF-II,insulin-like growth...
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Human
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P. pastoris (Yeast)
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Insulin-like growth factor 2 (IGF-2/IGF-II) is a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumor, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. IGF-2/IGF-II is a mediator of prolactin-induced alveologenesis; prolactin, IGF-2, and cyclin D1, all of which are overexpressed in br... |
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TMPY-00566
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CCL18 Protein, Human, Recombinant (His)
PARC,CCL18,CKb7,DC-CK1,chemokine (C-C motif) ligand 18,MIP-4...
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Human
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P. pastoris (Yeast)
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CCL18 is a chemotactic cytokine involved in the pathogenesis and progression of various disorders, including cancer. Proof showed high levels of CCL18 in the serum of epithelial ovarian carcinoma patients suggesting its potential as a circulating biomarker. CCL18 chemokine has an important role in chemokine-mediated tumor metastasis, and may serve as a potential predictor for poor survival outcomes for ovarian cancer. (CCL18) is predominantly secreted by M2-tumor associated macrophages (TAMs) a... |
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TMPH-01094
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CELA2A Protein, Human, Recombinant (His)
Chymotrypsin-like elastase family member 2A,CELA2A,ELA2A,Ela...
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Human
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P. pastoris (Yeast)
|
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Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism. Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and increases insulin sensitivity. CELA2A Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 27.9 kDa and the accession number is P08217. |
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TMPH-01093
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CELA2A Protein, Human, Recombinant (E. coli, His)
Elastase-2A,CELA2A,Chymotrypsin-like elastase family member ...
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Human
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E. coli
|
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Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism. Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and increases insulin sensitivity. CELA2A Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 29.9 kDa and the accession number is P08217. |
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TMPH-02323
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SLC30A8 Protein, Human, Recombinant (His)
Zinc transporter 8,Proton-coupled zinc antiporter SLC30A8,SL...
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Human
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E. coli
|
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Facilitates the accumulation of zinc from the cytoplasm into intracellular vesicles, being a zinc-efflux transporter. May be a major component for providing zinc to insulin maturation and/or storage processes in insulin-secreting pancreatic beta-cells. SLC30A8 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 43.6 kDa and the accession number is Q8IWU4. |
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TMPK-00751
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FSTL3 Protein, Human, Recombinant (His)
FSTL3,FLRGFSRP,Follistatin-like 3,FLRG
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Human
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HEK293 Cells
|
|
Follistatin-like 3 (FSTL3) is a novel cytokine that regulates insulin sensitivity and counteracts activin/myostatin signalling. In the present study, regulation of FSTL3 in renal dysfunction was investigated in both human chronic kidney disease (CKD) and acute kidney dysfunction (AKD). Furthermore, mFSTL3 expression was analysed in insulin-sensitive tissues in a mouse model of CKD. |
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TMPY-06479
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Cathepsin H Protein, Human, Recombinant (His)
CPSB,ACC-5,minichain,ACC4,ACC5,cathepsin H,ACC-4
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Human
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HEK293 Cells
|
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Proinflammatory cytokines decreased the expression of CTSH in human islets and primary rat beta-cells, and overexpression of CTSH protected insulin-secreting cells against cytokine-induced apoptosis. Cathepsin H Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.62 kDa and the accession number is NP_004381.2. |
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TMPH-02197
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TXNDC5 Protein, Human, Recombinant
Endoplasmic reticulum resident protein 46,TXNDC5,Thioredoxin...
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Human
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E. coli
|
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Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide-isomerase deficiency in yeast. TXNDC5 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 36.2 kDa and the accession number is Q8NBS9. |
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TMPH-01562
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IAPP Protein, Human, Recombinant (GST)
Insulinoma amyloid peptide,IAPP,Islet amyloid polyp...
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Human
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E. coli
|
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Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. IAPP Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 31.4 kDa and the accession number is P10997. |
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TMPH-02196
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TXNDC5 Protein, Human, Recombinant (GST)
Thioredoxin-like protein p46,Endoplasmic reticulum resident ...
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Human
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E. coli
|
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Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide-isomerase deficiency in yeast. TXNDC5 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 63.2 kDa and the accession number is Q8NBS9. |
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TMPY-05014
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INSL6 Protein, Human, Recombinant (His)
RIF1,insulin-like 6
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Human
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HEK293 Cells
|
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INSL6 (Insulin-Like 6) is a Protein Coding gene. An important paralog of this gene is RLN1. The protein encoded by this gene contains a classical signature of the insulin superfamily and is significantly similar to relaxin and relaxin-like factor. INSL6 is a newly identified insulin/relaxin family peptide hormone that is predominantly expressed by the male germ cells in testes. It may have a role in sperm development and fertilization. A recent murine study demonstrated that INSL6-knockout resul... |
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TMPY-04081
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Cathepsin H Protein, Mouse, Recombinant (His)
cathepsin H,AL022844
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Mouse
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HEK293 Cells
|
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Proinflammatory cytokines decreased the expression of CTSH in human islets and primary rat beta-cells, and overexpression of CTSH protected insulin-secreting cells against cytokine-induced apoptosis. Cathepsin H Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.6 kDa and the accession number is AAA82966.1. |
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TMPK-00863
|
LTK Potein, Human, Recombinant (His)
LTK,TYK1
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Human
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HEK293 Cells
|
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Leukocyte tyrosine kinase (LTK) is a receptor tyrosine kinase that belongs to the insulin receptor family. LTK is mainly expressed in pre B cells and brain. LTK Potein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 42.31 kDa and the accession number is P29376-1. |
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TMPY-05029
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INHBE Protein, Human, Recombinant (hFc)
inhibin beta E,inhibin β E
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Human
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HEK293 Cells
|
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INHBE (Inhibin Subunit Beta E) is a Protein Coding gene. This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate an inhibin beta subunit. INHBE was identified as a novel putative hepatokine with hepatic gene expression that positively correlated with insulin resistance and body mass index in humans. The quantitative real time-PCR analysis also showed an increase in INHBE gene expressi... |
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TMPK-01353
|
IGF2R Domain 1-3 Protein, Human, Recombinant (His & Avi)
CI-MPR,MPR 300,MPRI,M6P/IGF2R,M6PR,CD222,IGF-II receptor
|
Human
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HEK293 Cells
|
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The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer. IGF2R Domain 1-3 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 50.50 kDa and the accession number is P11717. |
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TMPK-01361
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IGF2R Protein, Human, Recombinant (His & Avi), Biotinylated
MPR 300,IGF-II receptor,M6PR,M6P/IGF2R,CD222,MPRI,CI-MPR
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Human
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HEK293 Cells
|
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The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer. IGF2R Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 164.90 kDa and the accession number is P11717. |
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TMPK-01355
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IGF2R Domain 1-7 Protein, Human, Recombinant (His & Avi)
IGF-II receptor,CI-MPR,CD222,M6P/IGF2R,MPRI,M6PR,MPR 300
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Human
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HEK293 Cells
|
|
The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer. IGF2R Domain 1-7 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 117.40 kDa and the accession number is P11717. |
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TMPJ-01166
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IGFBP-7 Protein, Mouse, Recombinant (His)
TAF,IGFBP-rP1,Insulin-like growth factor-binding pr...
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Mouse
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HEK293 Cells
|
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Insulin-like growth factor-binding protein 7(IGFBP-7) is a secreted glycosylated protein that contains three protein domain modules. IGFBP7 contains an N-terminal IGFBP domain, followed by a Kazal-type serine proteinase inhibitor domain and a C-terminal immunoglobulin-like C2-type domain. Human and mouse IGFBP7 are highly homologous and share 94% aa sequence identity. It is expressed in many normal tissues and in cancer cells. It is abundantly expressed in high endothelial venules (HEVs) of bloo... |
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TMPJ-00781
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LR3-IGF-1 Protein, Mouse, Recombinant (His)
IGF1,insulin-like growth factor 1,Insulin-...
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Mouse
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E. coli
|
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Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mouse IGF-I is synthesized as two precursor isoforms with alternate N- and C-terminal propeptides. These isoforms are differentially expressed by various tissues. Mature mouse IGF-I shares 94% and 99% aa sequence identity with human and rat IGF-I, respectively, and exhibits cross-species activity. It shares 60% aa sequence identity with mature mouse IGF-II. IG... |
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TMPH-02022
|
RXFP2 Protein, Human, Recombinant (His & Myc)
G-protein coupled receptor 106,Relaxin receptor 2,Relaxin fa...
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Human
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E. coli
|
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Receptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3). RXFP2 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 21.1 kDa and the accession number is Q8WXD0. |
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TMPH-01385
|
GLP1R Protein, Human, Recombinant (His)
Glucagon-like peptide 1 receptor,GLP1R
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Human
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HEK293 Cells
|
|
G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1. GLP1R Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 18.3 kDa and the accession number is P43220. |
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TMPH-01384
|
GLP1R Protein, Human, Recombinant (E. coli, His)
GLP1R,Glucagon-like peptide 1 receptor
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Human
|
E. coli
|
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G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1. GLP1R Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 18.3 kDa and the accession number is P43220. |
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TMPH-01462
|
HNRNPH1 Protein, Human, Recombinant (GST)
HNRNPH1,Heterogeneous nuclear ribonucleoprotein H
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Human
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E. coli
|
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This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG). HNRNPH1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system... |
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TMPY-04387
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AKT2 Protein, Human, Recombinant (His & GST)
RAC-β,RAC-BETA,HIHGHH,PKBBETA,PKBβ,PRKBB,PKBB,v-akt murine t...
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Human
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Baculovirus Insect Cells
|
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AKT (AK mouse plus Transforming or Thymoma) is a frequent oncogene expressed in most tissues which includes three isoforms AKT1, AKT2, and AKT3. Hyperactivation of AKT signaling is a central key in many human cancer progressions, through modulating angiogenesis, tumor growth, and cell migration, invasion, metastasis, and chemoresistance. Among all three isoforms, AKT2 is most related to cancer cell invasion, metastasis, and survival. Amplification and overexpression of AKT2 have been shown in ma... |
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TMPH-01540
|
Intelectin-1/ITLN1 Protein, Human, Recombinant (His & Myc)
Galactofuranose-binding lectin,Endothelial lectin HL-1,Intel...
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Human
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E. coli
|
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Lectin that specifically recognizes microbial carbohydrate chains in a calcium-dependent manner. Binds to microbial glycans that contain a terminal acyclic 1,2-diol moiety, including beta-linked D-galactofuranose (beta-Galf), D-phosphoglycerol-modified glycans, D-glycero-D-talo-oct-2-ulosonic acid (KO) and 3-deoxy-D-manno-oct-2-ulosonic acid (KDO). Binds to glycans from Gram-positive and Gram-negative bacteria, including K.pneumoniae, S.pneumoniae, Y.pestis, P.mirabilis and P.vulgaris. Does not ... |
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TMPY-02519
|
BLVRB Protein, Human, Recombinant (His)
HEL-S-10,biliverdin reductase B,FLR,BVRB,SDR43U1
|
Human
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E. coli
|
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Biliverdin reductase (hBVR) is a serine/threonine kinase that catalyzes reduction of the heme oxygenase (HO) activity product, biliverdin, to bilirubin. BVR consists of an N-terminal dinucleotide-binding domain (Rossmann-fold) and a C-terminal domain that contains a six-stranded β-sheet that is flanked on one face by several α-helices. The C-terminal and N-terminal domains interact extensively, forming the active site cleft at their interface. Biliverdin reductase (BVR) catalyzes the last step i... |
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TMPY-01960
|
Munc18c/STXBP3 Protein, Human, Recombinant (His & GST)
syntaxin binding protein 3,MUNC18C,UNC-18C,MUNC18-3,PSP
|
Human
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Baculovirus Insect Cells
|
|
Syntaxin-binding protein 3, also known as Platelet Sec1 protein, Protein unc-18 homolog 3, Protein unc-18 homolog C, Unc-18C, Unc18-3 and STXBP3, is a cytoplasm protein which belongs to the STXBP/unc-18/SEC1 family. STXBP3 is expressed in cells that exhibit granule exocytosis, such as neutrophils, mast cells, platelets and endothelial cells. STXBP3, together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking / fusion of intracellular GLUT4-containing vesic... |
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TMPJ-01082
|
IGFBP-5 Protein, Mouse, Recombinant (His)
IGFBP-5,IGF-binding protein 5,BP-5,Insulin-like gro...
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Mouse
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HEK293 Cells
|
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Mouse Insulin-like growth factor-binding protein 5(IGFBP-5) belongs to the superfamily of insulin-like growth factor (IGF) binding proteins. It contains 1 IGFBP N-terminal domain and 1 thyroglobulin type-1 domain. Mouse IGFBP-5 shows 97% aa sequence identity with those of human and rat IGFBP-5. It is expressed mostly in kidney, uterus and gastrocnemius muscle. It also expressed by fibroblasts, myoblasts and osteoblasts, making it the predominant IGFBP found in bone extracts. IGFBP-5 has a strong... |
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TMPJ-00014
|
Resistin Protein, Human, Recombinant (His)
Resistin,C/EBP-epsilon-regulated myeloid-specific secreted c...
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Human
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E. coli
|
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Resistin known as adipose tissue-specific secretory factor (ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein (XCP1) that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. The length of the resistin pre-peptide in human is 108 amino acid residues and in the mouse and rat it is 114 aa; the molecular weight is ~12.5 kDa. Resistin is a cytokine whose physiologic role has been the subject of much controversy regarding its involvement wit... |
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TMPJ-00286
|
ANGPTL3 Protein, Human, Recombinant (hFc)
ANGPTL3,ANGPT5,Angiopoietin-related protein 3,ANG-5,Angiopoi...
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Human
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HEK293 Cells
|
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Angiopoietin-like 3 (ANGPTL3) is a secreted glycoprotein that is structurally related to the angiopoietins. Mature human ANGPTL3 contains an N-terminal coiled coil domain and a C-terminal fibrinogen-like domain. ANGPTL3 is expressed in the liver from early in development through adulthood. Full length ANGPTL3 circulates in the plasma as do the proteolytically separated N-and C-terminal segments containing the coiled coil domain and fibrinogen-like domains,respectively. ANGPTL3 directly inhibits ... |
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TMPJ-01177
|
NOV/CCN3 Protein, Mouse, Recombinant (His)
CCN family member 3,Nephroblastoma-overexpressed gene protei...
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Mouse
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HEK293 Cells
|
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NOV, also called CCN3, is a secreted protein of CCN family members. CCN family members are highly conserved cysteine rich proteins sharing a common modular structure having 4 conserved domains, insulin-like growth factor-binding protein (IGFBP) domain, von Willebrand type C (VWC) domain, thrombospondin-1 (TSP-1) domain, and C-terminal (CT) domain (absent in CCN5). By specific interactions with these domains, CCN proteins modulate multiple signalling pathways including BMPs, Wnt, TGFs, Notch and ... |
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TMPY-02135
|
S100A16 Protein, Human, Recombinant
S100F,DT1P1A7,S100 calcium binding protein A16,MGC17528,AAG1...
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Human
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E. coli
|
|
S100A16 is a member of S100 protein superfamily that carries calcium-binding EF-hand motifs. S100 proteins are cell- and tissue-specific and are involved in many intra- and extracellular processes through interacting with specific target proteins. S100A16 expression was found to be astrocyte-specific. The S100A16 protein was found to accumulate within nucleoli and to translocate to the cytoplasm in response to Ca(2+) stimulation. The homodimeric structure of human S100A16 in the apo state has be... |
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TMPY-04813
|
ACAT2 Protein, Rat, Recombinant (His)
acetyl-CoA acetyltransferase 2
|
Rat
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E. coli
|
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Acyl-coenzyme A: cholesterol acyltransferase (ACAT) is an intracellular enzyme that produces cholesteryl esters in various tissues. In mammals, two ACAT genes (ACAT1 and ACAT2) have been identified. Together, these two enzymes are involved in storing cholesteryl esters as lipid droplets, in macrophage foam-cell formation, in absorbing dietary cholesterol, and in supplying cholesteryl esters as part of the core lipid for lipoprotein synthesis and assembly. The key difference in tissue distributio... |
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TMPK-01534
|
Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human&Mouse, MHC (His & Avi)
RING12,PSMB9,Proteasome chain 7,RMF,LMP-2,LMP2,MHC,Macropain...
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Human & Mouse
|
HEK293 Cells
|
|
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of ma... |
|
TMPK-01523
|
Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Monomer Protein, Human&Mouse, MHC (His & Avi)
WAGR,WT33,AWT1,GUD,RMF,WT1,WIT-2,MHC,NPHS4GUD
|
Human & Mouse
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HEK293 Cells
|
|
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, endometrioid, clear cell, and mucinous carcinomas of the peritoneum, fallopian tube, ovary, and endometrium.The Human HLA-A*0201 WT-1 (RMFPNAPYL) complex Protein is a complex of HLA-A*0201 of the MHC Class I, B2M and RMFPNAPYL peptide of the WT-1. |
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TMPK-01535
|
Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Tetramer Protein, Human&Mouse, MHC (His & Avi)
Macropain chain 7,LMP2,Proteasome chain 7,RING12,PSMB9,MHC,R...
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Human & Mouse
|
HEK293 Cells
|
|
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of ma... |
|
TMPK-01522
|
Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Tetramer Protein, Human&Mouse, MHC (His & Avi)
RMF,WT33,WIT-2,MHC,WAGR,AWT1,GUD,WT1,NPHS4GUD
|
Human & Mouse
|
HEK293 Cells
|
|
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, endometrioid, clear cell, and mucinous carcinomas of the peritoneum, fallopian tube, ovary, and endometrium.The Human HLA-A*0201 WT-1 (RMFPNAPYL) complex Protein is a complex of HLA-A*0201 of the MHC Class I, B2M and RMFPNAPYL peptide of the WT-1. |
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