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Search Results for " influx "

Targets Recommended: Adenosine Receptor

73

抑制剂 & 化合物

18

天然产物

21

重组蛋白

2

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T7736	2-Chloroadenosine	Adenosine Receptor	GPCR/G Protein; Neuroscience
	2-Chloroadenosine 是腺苷类似物，可防止大鼠海马缺血细胞长期丢失。它是尿苷内流 (Ki:33 μM) 的竞争性抑制剂，高亲和力与硝基苄基硫肌苷结合 (Ki:0.18 mM)。它是一种人红细胞核苷转运体的转运渗透剂。
T6777	Bay K 8644 (±)-BAY-K-8644,SQ 28,873	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Bay K 8644 (SQ 28,873)是一种二氢吡啶化合物，是一种选择性的 L 型 Ca2+ 通道激活剂，IC50 为 17.3 nM。它通过增加通道的开放时间来增加通过肌膜 Ca2+通道的 Ca2+流入。
T0370	Pheniramine maleate Daneral,Inhiston,Trimetose,马来酸非尼拉敏	5-HT Receptor; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Pheniramine maleate (Trimetose) 是一种具有抗组胺和血管扩张特性的烷基胺衍生物，可与组胺 H1 受体结合，从而抑制磷脂酶 A2 和内皮源性松弛因子一氧化氮的产生。
T40101	(±)-1,2-Diolein 1,2-Dioleoyl-rac-glycerol,甘油1,2-二油酸酯	PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	(±)-1,2-Diolein (1,2-Dioleoyl-rac-glycerol) 是一种PKC 激活剂，可以增加肌小管 Ca2+内流。
T2711	Chembridge-5861528 TCS 5861528	TRP/TRPV Channel	Membrane transporter/Ion channel
	Chembridge-5861528 (TCS 5861528) 是有效的 TRPA1离子通道阻断剂。
T6530	HC-030031 2-(1,3-二甲基-2,6-二氧代-2,3-二氢-1H-嘌呤-7(6H)-基)-N-(4-异丙基苯基)乙酰胺,HC030031,TOSLAB 829227	TRP/TRPV Channel	Membrane transporter/Ion channel
	HC-030031 (TOSLAB 829227) 是一种有效的TRPA1选择性抑制剂，拮抗福尔马林和AITC 诱发的钙流入，IC50分别为5.3±0.2和6.2±0.2μM。
T16687	Pyr3	TRP/TRPV Channel	Membrane transporter/Ion channel
	Pyr3 是一种选择性瞬时受体电位经典通道 3 抑制剂。 Pyr3 以剂量依赖性方式抑制 TRPC3 介导的 Ca2+ 内流 (IC50 = 700 nM)。
T12234	NMDA-IN-1	NMDAR	Neuroscience
	NMDA-IN-1是一种 NR2B 选择性 NMDA 拮抗剂，对NMDA 的Ki 值为 0.85 nM，对NR2B Ca2+ influx 的IC50值为 9.7 nM。
TNU0864	HUP30	Potassium Channel; Calcium Channel	Membrane transporter/Ion channel; Metabolism
	HUP30是一种强效的血管舒张剂。HUP30可以刺激可溶性鸟苷酸环化酶，激活 K+离子通道，阻断细胞外 Ca2+的内流。
T1425	Pemirolast potassium BMY 26517,TWT-8152,吡嘧司特钾	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Pemirolast potassium (TWT-8152) 是 H1组胺受体拮抗剂和肥大细胞稳定剂，是一种具有抗过敏特性的嘧啶酮衍生物。
T0222	Proparacaine hydrochloride 盐酸丙美卡因,Proparacaine HCl,Proxymetacaine Hydrochloride	Apoptosis; Sodium Channel	Apoptosis; Membrane transporter/Ion channel
	Proparacaine hydrochloride (Proparacaine HCl) 是 Lidocaine 的衍生物，具有糖皮质激素样活性和免疫调节作用。
T1768	7ACC2	Mitochondrial Metabolism; Monocarboxylate transporter	Membrane transporter/Ion channel; Metabolism
	7ACC2 是单羧酸盐转运蛋白抑制剂，IC50为 11 nM。它还是线粒体丙酮酸转运的有效抑制剂，可抑制乳酸涌入，通过抑制乳酸通量来发挥抗癌作用。
T6645	Ropivacaine hydrochloride monohydrate Ropivacaine HCl,Ropivacaine HCl monohydrate,LEA 103,盐酸罗哌卡因,盐酸罗哌卡因一水合物,LEA-103 HCl	Potassium Channel; Sodium Channel	Membrane transporter/Ion channel
	Ropivacaine hydrochloride monohydrate (LEA-103 HCl) 是钠通道阻断剂，通过可逆地抑制钠离子内流从而引起神经纤维脉冲传导阻滞。Ropivacaine HCl monohydrate 也是 K2P(双孔钾通道)TREK-1的抑制剂。在动物实验模型中，Ropivacaine HCl monohydrate 可用于神经性疼痛的缓解。
T5845	7ACC1 DEAC,香豆素D1421,Coumarin D 1421,7-(二乙胺基）-2-氧代-2-苯并吡喃-3-羧酸,7-(Diethylamino)coumarin-3-carboxylic acid,D 1421	Monocarboxylate transporter	Membrane transporter/Ion channel
	7ACC1 (D 142) 抑制表达MCT1和MCT4肿瘤细胞的乳酸涌入，能选择性干扰肿瘤微环境乳酸通量。
T11102	DS16570511	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	DS16570511 是一种细胞渗透性的线粒体钙单核转运蛋白(mitochondrial calcium uniporter)小分子抑制剂，阻断了依赖于 MCU 或 MICU1 的 Ca2+流入增加。
T16688	Pyr6 N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-3-fluoro-4-pyridinecarboxamide	TRP/TRPV Channel	Membrane transporter/Ion channel
	Pyr6 (N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-3-fluoro-4-pyridinecarboxamide)是选择性的 TRPC3抑制剂，IC50值为0.49uM。
T10782	CGP52411 DAPH	EGFR; Beta Amyloid	Angiogenesis; JAK/STAT signaling; Neuroscience; Tyrosine Kinase/Adaptors
	CGP52411 是一种具有口服活性的 ATP 竞争性 EGFR 抑制剂（IC50：0.3 μM）。 CGP52411 阻止 Ca2+ 离子有毒流入神经元细胞，并显着抑制和逆转 β-淀粉样蛋白 Aβ42 原纤维聚集体的形成。 CGP52411 可用于阿尔茨海默病的研究。
T1435	Praziquantel 吡喹酮,Pyquiton,Droncit,Biltricide	Calcium Channel; Antibiotic; Parasite	Membrane transporter/Ion channel; Metabolism; Microbiology/Virology
	Praziquantel (Droncit) 是一种外消旋混合物，由 (R)-Praziquantel 和 (S)-Praziquantel 组成。它可研究血吸虫病。
T16686	Pyr10	TRP/TRPV Channel	Membrane transporter/Ion channel
	Pyr10 是吡唑衍生物，是TRPC3通道的选择性抑制剂。Pyr10抑制卡巴可刺激的TRPC3转染的 HEK293 细胞中的 Ca2+流入。它具有区分受体操纵的TRPC3和天然基质相互作用分子 1 (STIM1)/Orai1 通道的能力。
T0018	Procainamide hydrochloride Procapan,Procainamide HCl,Pronestyl,Procanbid,盐酸普鲁卡因胺	DNA Methyltransferase; Sodium Channel; AChR; Autophagy	Autophagy; Chromatin/Epigenetic; Membrane transporter/Ion channel; Neuroscience
	Procainamide hydrochloride (Procapan) 是一种用于研究心律失常的抗心律失常制剂。
T0468	Lidocaine Lignocaine,Alphacaine,Xylocaine,利多卡因	Apoptosis; ERK; NF-κB; MEK; Sodium Channel; Histamine Receptor	Apoptosis; GPCR/G Protein; Immunology/Inflammation; MAPK; Membrane transporter/Ion channel; Neuroscience; NF-κB
	Lidocaine (Alphacaine) 是一种酰胺衍生物，抑制涉及复杂电压和依赖性的钠通道，可用于研究室性心律失常。它通过调节 miR-145 表达和进一步抑制 MEK/ERK 和 NF-κB 信号通路来减少胃癌细胞的生长，迁移和侵袭。
T15257	Etripamil MSP-2017,(-)-MSP-2017	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Etripamil (MSP-2017) 是一种短效L 型钙通道拮抗剂，可用于治疗阵发性室上性心动过速的研究。它通过抑制房室结细胞中钙慢通道的钙离子流入，显示房室结传导并延长房室结不应期
TP1910L1	CALP1 acetate CALP1 acetate(145224-99-3 free base)	CaMK	Neuroscience
	CALP1 acetate 是一种钙调蛋白 (CaM) 激动剂（Kd 为 88 µM），可与 CaM EF-hand/Ca2+ 结合位点结合。 CALP1 通过抑制钙通道的开放来阻断钙流入和细胞凋亡（IC50 为 44.78 µM）。 CALP1 阻断谷氨酸受体通道并阻断储存操作的非选择性阳离子通道。 CALP1 激活依赖于 CaM 的磷酸二酯酶活性。
T1613	Hydralazine hydrochloride Hydralazine HCl,Apresoline,盐酸肼屈嗪	MAO; HIF/HIF Prolyl-Hydroxylase	Chromatin/Epigenetic; Metabolism; Neuroscience
	Hydralazine hydrochloride (Apresoline) 是一种直接作用的血管舒张剂，可抗高血压。
T1146	Nifedipine BAY-a-1040,Procardia XL,Procardia,硝苯地平,Adalat	CaMK; Potassium Channel; Calcium Channel; Autophagy	Autophagy; Membrane transporter/Ion channel; Metabolism; Neuroscience
	Nifedipine (Procardia) 是一种二氢吡啶类钙通道阻滞剂，可抑制细胞外钙离子跨膜流入心肌和血管平滑肌细胞，导致主要冠状动脉和全身动脉扩张，降低心肌收缩力。它常用于心肌功能不全的相关研究。
T22043	BCATc Inhibitor 2	Others	Others
	BCATc Inhibitor 2 是选择性分支链氨基转移酶抑制剂，可用于神经退行性疾病的研究。能够抑制 rBCATc (IC50:0.2 μM)，hBCATc (IC50:0.8 μM)、 rBCATm (IC50:3.0 μM)。其中BCATc 也称为 BCAT1，存在于细胞质基质中的亚型。
T5148	Atosiban acetate RW22164,Atosiban acetate (90779-69-4 free base),RWJ22164,醋酸阿托西班	Oxytocin Receptor; Vasopressin Receptor	Endocrinology/Hormones; GPCR/G Protein
	Atosiban acetate (RW22164) 是一种脱氨基催产素类似物，是一种九肽，也是竞争性的催产素受体拮抗剂。它是一种宫缩抑制剂，可用于自发早产的研究。
T3979	Emedastine LY188695,依美斯汀,Emadine	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Emedastine (LY188695) 是一种可口服的，选择性和高亲和力的组胺 H1受体拮抗剂，Ki 值为 1.3 nM。它是苯并咪唑衍生物，可用于过敏性鼻炎、过敏性皮肤疾病和过敏性结膜炎的研究。
T27639	ITH-12575	Others	Others
	ITH-12575 is an inhibitor of Mitochondrial Na+/Ca2+ exchange (mNCX). ITH12575 reduces Ca(2+) influx through CALHM1 at low micromolar concentrations.
T26376	11-deoxy-PGF2a 11-deoxyPGF2a,11-deoxy PGF2a	Others	Others
	11-deoxy-PGF2a, a selective activator of TREK-2 channels, stimulates DRG c-fiber nociceptor K2P currents and limits calcium influx.
T4316	ML365	Potassium Channel	Membrane transporter/Ion channel
	ML365 是有效的，选择性的双孔结构域钾通道TASK1/KCNK3抑制剂，IC50为 4 nM。它可用于检查 TASK1 通道的特定作用。
T68742	Inamrinone lactate	Others	Others
	Inamrinone lactate is a positive inotropic cardiotonic with vasodilator properties, phosphodiesterase inhibitory activity, and the ability to stimulate calcium ion influx into the cardiac cell.
T37763	BTD	Others	Others
	Selective TRPC5 activator (EC50 = 1.4 μM in a calcium influx assay, 1.3 μM in whole cell patch clamp assay). Displays >14.5-fold selectivity for TRPC5 over other TRP channels (EC50 = 20.6 μM for TRPM8). Also activates TRPC1:5 and TRPC4:5 heteromers. Beckmann et al (2017) A benzothiadiazine derivative and methylprednisolone are novel and selective activators of transient receptor potential canonical 5 (TRPC5) channels. Cell Calcium. 66 10 PMID:28807145
T71735	AAL1	Others	Others
	AAL1 is an inhibitor of dark-grown Arabidopsis thaliana seedlings, functioning through auxin receptor Transport Inhibitor Response1 (TIR1) and depending on auxin influx and efflux carriers.
T14829	Bromoenol lactone (6E)-Bromoenol lactone	Phospholipase	Metabolism
	Bromoenol lactone is a suicide-based irreversible, selective, potent inhibitor of calcium-independent phospholipase A2 (iPLA2β; IC50: ~7 μM). It inhibits antigen-stimulated mast cell exocytosis without blocking Ca2+ influx.
T68361	Asocainol hydrochloride	Others	Others
	Asocainol hydrochloride ia an antiarrhythmic drug which inhibits slow Ca2+ influx. This is accompanied by alterations in normal Na+-carried action potentials. Therefore, Asocainol not only inhibits Ca2+ inflow but also interferes with the fast inward Na+ current.
T40750	12,14-Dichlorodehydroabietic acid	Others	Others
	12,14-Dichlorodehydroabietic acid, a chlorinated resin acid, exhibits potent calcium-activated potassium (BK) channel opening activity. It effectively inhibits GABA-dependent chloride influx in the mammalian brain, functioning as a non-competitive antagonist of GABA A receptors. Moreover, 12,14-Dichlorodehydroabietic acid induces an elevation in cytosolic free calcium levels and promotes the release of neurotransmitters.
T62660	MLN3126	Others	Others
	MLN3126 是一种口服具有活力的强效 CCR9 拮抗剂。 MLN3126 抑制 CCL25 诱导的钙动员 (calcium mobilization) 和小鼠初级胸腺细胞趋化 (chemotaxis) (IC50: 6.3 nM)。
T79618	M3/PDE4 modulator-1	Others	Others
	M3/PDE4 modulator-1 (10f) 为多功能化合物，具备M3mAChR拮抗和PDE4抑制作用。于OVA大鼠模型中，M3/PDE4 modulator-1 (10-1000 nM/kg；iv) 能降低半胱氨酸嗜酸性粒细胞内流。
T37475	Cyclic ADP-Ribose (ammonium salt) cADP-Ribose,cADPR,Cyclic ADP-Ribose (ammonium salt)	Others	Others
	Cyclic ADP-ribose (cADP-ribose) is an endogenous metabolite of NAD+ that mobilizes the release of stored Ca2+ in the endoplasmic reticulum via ryanodine receptors in various cell types.[1],[2],[3],[4],[5] This second messenger is generated via the cADP-ribose synthases CD38 and CD157.[6],[5],[7] cADP-Ribose may also trigger the cell surface Ca2+ influx channel TRPM2 in a temperature-dependent manner.[8] In vitro, cADP-ribose modulates Ca2+ signaling in rat and mouse cardiomyocytes treated with i...
T61438	Propiverine	Others	Others
	Propiverine is a potent antimuscarinic agent that effectively inhibits cellular calcium influx, leading to the reduction of muscle spasm. It exhibits neurotropic and musculotropic effects specifically on the smooth muscles of the urinary bladder. Propiverine proves valuable in research concerning overactive bladder (OAB) [1] [2].
T80441	FS-2	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	FS-2，一种特异性L型CaV通道抑制剂，能够阻断RIN beta 细胞中，高K+或葡萄糖刺激导致的L型Ca2+内流。
T37759	Fura-2 (potassium salt)
	Fura-2 is a ratiometric fluorescent calcium indicator that can be used to detect calcium in cells. [1] It is a pentacarboxylate that displays excitation maxima of 340 and 380 nm at high and low calcium concentrations, respectively, when the emission is fixed at 510 nm, enabling determination of ratiometric measurements of calcium influx in live cells.
T37760	Fura-2 (sodium salt)
	Fura-2 is a ratiometric fluorescent calcium indicator that can be used to detect calcium in cells. It is a pentacarboxylate that displays excitation maxima of 340 and 380 nm at high and low calcium concentrations, respectively, when the emission is fixed at 510 nm, enabling determination of ratiometric measurements of calcium influx in live cells.
T70224	Bupivacaine tartrate	Others	Others
	Bupivacaine is a BK/SK, Kv1, Kv3, TASK-2 K Channel and voltage-gated Na channel blocker used as an anesthetic. It maybe neurotoxic at high does, inducing apoptosis in neuroblastoma cells. It acts by binding to the intracellular portion of voltage-gated sodium channels and blocking sodium influx into nerve cells.
T26447	A 78773 A78773,A-78773	Others	Others
	A 78773 is a potent, selective, direct, and reversible 5-lipoxygenase inhibitor. It has activity in a variety of purified cells and in more complex biological systems such as whole blood, lung fragments, and tracheal tissues. A 78773 acts against inflamma
T23102	OBAA	Others	Others
	OBAA 是一种有效的磷脂酶 A2 (PLA2) 抑制剂(IC50= 70 nM)，并且在布氏锥虫中阻断 Melittin 诱导的 Ca2+流入(IC50= 0.4 μM)。
T40757	1-Stearoyl-2-arachidonoyl-sn-glycerol	PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	1-Stearoyl-2-arachidonoyl-sn-glycerol (DAG) 是一种二酰基甘油 (DAG)的底物，可被水解为2-花生四烯酰甘油。 1-Stearoyl-2-arachidonoyl-sn-glycerol 可以激活 PKC，可诱导 Ca2+ 流入，可诱导气管平滑肌收缩。
T37058	D-myo-Inositol-1,3,4,5-tetraphosphate (sodium salt)	Others	Others
	D-myo-Inositol-1,3,4,5-tetraphosphate (Ins(1,3,4,5)-P4) is formed by the phosphorylation of Ins(1,4,5)P3 by inositol 1,4,5-triphosphate 3-kinase. Ins(1,3,4,5)-P4 increases intracellular calcium levels by two distinct mechanisms: opening calcium channels on both the endoplasmic reticulum to release calcium from internal stores and on the plasma membrane to allow the influx of calcium from outside the cell.
T37975	13(S)-HODE-biotin	Others	Others
	13(S)-HODE is the lipoxygenase metabolite of linoleic acid. 13(S)-HODE modulates the platelet-activating factor, leukotriene B4, and formyl-Met-Leu-Phe-induced calcium influx in human polymorphonuclear leukocytes. The mechanism by which 13(S)-HODE elicits its inhibitory effect is still unclear. The use of biotinylated 15(S)-HETE as a probe for detecting binding proteins and/or receptors that specifically bind 15(S)-HETE provides a basis for similar use of 13(S)-HODE-biotin.

化合物

2-Chloroadenosine

Cat.No: T7736

Target: Adenosine Receptor

Cat.No: T6777

Synonym: (±)-BAY-K-8644,SQ 28,873

Target: Calcium Channel

Pheniramine maleate

Cat.No: T0370

Synonym: Daneral,Inhiston,Trimetose,马来酸非尼拉敏

Target: 5-HT Receptor, Histamine Receptor

(±)-1,2-Diolein

Cat.No: T40101

Synonym: 1,2-Dioleoyl-rac-glycerol,甘油1,2-二油酸酯

Target: PKC

Chembridge-5861528

Cat.No: T2711

Synonym: TCS 5861528

Target: TRP/TRPV Channel

Cat.No: T6530

Synonym: 2-(1,3-二甲基-2,6-二氧代-2,3-二氢-1H-嘌呤-7(6H)-基)-N-(4-异丙基苯基)乙酰胺,HC030031,TOSLAB 829227

Target: TRP/TRPV Channel

Cat.No: T16687

Target: TRP/TRPV Channel

Cat.No: T12234

Target: NMDAR

Cat.No: TNU0864

Target: Potassium Channel, Calcium Channel

Pemirolast potassium

Cat.No: T1425

Synonym: BMY 26517,TWT-8152,吡嘧司特钾

Target: Histamine Receptor

Proparacaine hydrochloride

Cat.No: T0222

Synonym: 盐酸丙美卡因,Proparacaine HCl,Proxymetacaine Hydrochloride

Target: Apoptosis, Sodium Channel

Cat.No: T1768

Target: Mitochondrial Metabolism, Monocarboxylate transporter

Ropivacaine hydrochloride monohydrate

Cat.No: T6645

Synonym: Ropivacaine HCl,Ropivacaine HCl monohydrate,LEA 103,盐酸罗哌卡因,盐酸罗哌卡因一水合物,LEA-103 HCl

Target: Potassium Channel, Sodium Channel

Cat.No: T5845

Synonym: DEAC,香豆素D1421,Coumarin D 1421,7-(二乙胺基）-2-氧代-2-苯并吡喃-3-羧酸,7-(Diethylamino)coumarin-3-carboxylic acid,D 1421

Target: Monocarboxylate transporter

Cat.No: T11102

Target: Calcium Channel

Cat.No: T16688

Synonym: N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-3-fluoro-4-pyridinecarboxamide

Target: TRP/TRPV Channel

Cat.No: T10782

Synonym: DAPH

Target: EGFR, Beta Amyloid

Cat.No: T1435

Synonym: 吡喹酮,Pyquiton,Droncit,Biltricide

Target: Calcium Channel, Antibiotic, Parasite

Cat.No: T16686

Target: TRP/TRPV Channel

Procainamide hydrochloride

Cat.No: T0018

Synonym: Procapan,Procainamide HCl,Pronestyl,Procanbid,盐酸普鲁卡因胺

Target: DNA Methyltransferase, Sodium Channel, AChR, Autophagy

Cat.No: T0468

Synonym: Lignocaine,Alphacaine,Xylocaine,利多卡因

Target: Apoptosis, ERK, NF-κB, MEK, Sodium Channel, Histamine Receptor

Cat.No: T15257

Synonym: MSP-2017,(-)-MSP-2017

Target: Calcium Channel

Cat.No: TP1910L1

Synonym: CALP1 acetate(145224-99-3 free base)

Target: CaMK

Hydralazine hydrochloride

Cat.No: T1613

Synonym: Hydralazine HCl,Apresoline,盐酸肼屈嗪

Target: MAO, HIF/HIF Prolyl-Hydroxylase

Cat.No: T1146

Synonym: BAY-a-1040,Procardia XL,Procardia,硝苯地平,Adalat

Target: CaMK, Potassium Channel, Calcium Channel, Autophagy

BCATc Inhibitor 2

Cat.No: T22043

Target: Others

Atosiban acetate

Cat.No: T5148

Synonym: RW22164,Atosiban acetate (90779-69-4 free base),RWJ22164,醋酸阿托西班

Target: Oxytocin Receptor, Vasopressin Receptor

Cat.No: T3979

Synonym: LY188695,依美斯汀,Emadine

Target: Histamine Receptor

Cat.No: T27639

Target: Others

Cat.No: T26376

Synonym: 11-deoxyPGF2a,11-deoxy PGF2a

Target: Others

Cat.No: T4316

Target: Potassium Channel

Inamrinone lactate

Cat.No: T68742

Target: Others

Cat.No: T37763

Target: Others

Cat.No: T71735

Target: Others

Bromoenol lactone

Cat.No: T14829

Synonym: (6E)-Bromoenol lactone

Target: Phospholipase

Asocainol hydrochloride

Cat.No: T68361

Target: Others

12,14-Dichlorodehydroabietic acid

Cat.No: T40750

Target: Others

Cat.No: T62660

Target: Others

M3/PDE4 modulator-1

Cat.No: T79618

Target: Others

Cyclic ADP-Ribose (ammonium salt)

Cat.No: T37475

Synonym: cADP-Ribose,cADPR,Cyclic ADP-Ribose (ammonium salt)

Target: Others

Cat.No: T61438

Target: Others

Cat.No: T80441

Target: Calcium Channel

Fura-2 (potassium salt)

Cat.No: T37759

Fura-2 (sodium salt)

Cat.No: T37760

Bupivacaine tartrate

Cat.No: T70224

Target: Others

Cat.No: T26447

Synonym: A78773,A-78773

Target: Others

Cat.No: T23102

Target: Others

1-Stearoyl-2-arachidonoyl-sn-glycerol

Cat.No: T40757

Target: PKC

D-myo-Inositol-1,3,4,5-tetraphosphate (sodium salt)

Cat.No: T37058

Target: Others

13(S)-HODE-biotin

Cat.No: T37975

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TN1121	Evocarpine	Apoptosis; cAMP; Anti-infection; Calcium Channel; Antibacterial	Apoptosis; GPCR/G Protein; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology
	Evocarpine 是从 Evodiae fructus 分离得到的一种喹诺酮类生物碱，有抗细菌活性。它可通过电压依赖性钙通道抑制 Ca2+内流。
T8118	Bekanamycin Kanamycin B,卡那霉素,卡那霉素 B	Antibacterial; Antibiotic	Microbiology/Virology
	Bekanamycin (Kanamycin B) 是一种提取自 Streptomyces kanamyceticus 的氨基糖苷类抗生素，抑制一系列革兰氏阳性和阴性细菌。
T23735	Jamaicin An-Co-A4,AnCoA-4,An Co A4,AnCoA4	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Jamaicin (AnCoA4) 是一种从鸡血藤植物中提取的异黄酮，是一种 STIM1-Orai1 通道的抑制剂，可阻断钙离子流入，减少其与 STIM1 的相互作用，抑制 T 细胞的活化。
TN1154	Nepetin 6-Methoxyluteolin,泽兰黄酮,6-甲氧基藤黄菌素	Calcium Channel; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience
	Nepetin (6-Methoxyluteolin) 是一种分离自Eupatorium ballotaefoliumHBK 中的天然类黄酮，具有有效的抗炎作用。它在 ARPE-19 细胞中能够抑制IL-6(IC50:4.43 μM) 、IL-8 (IC50:43.42 μM) 、MCP-1 (IC50:4.17 μM) 的分泌。
TN1136	Procyanidin A1 原花青素 A1,Proanthocyanidin A1,原花色素A1	LDL; Calcium Channel; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Membrane transporter/Ion channel; Metabolism
	Procyanidin A1 (Proanthocyanidin A1) 是一种原花青素二聚体，具有抗过敏作用，可抑制蛋白激酶 C 激活下游脱粒或 RBL-213 细胞内部储存的 Ca2+流入。
T5S0890	Oleandrin Neriostene,Folinerin,Foliandrin,欧夹竹桃苷	Apoptosis; ATPase; Potassium Channel; Sodium Channel	Apoptosis; Membrane transporter/Ion channel
	Oleandrin (Folinerin) 是夹竹桃属中的一种类固醇，可抑制Na+/K+-ATPase 活性，IC50为 620 nM。
TN2322	Yangambin	Calcium Channel; PAFR	GPCR/G Protein; Membrane transporter/Ion channel; Metabolism
	Yangambin 是从诸如番荔枝科植物中分离出来的呋喃木脂素，是选择性PAF 受体拮抗剂，通过调控Ca2+通道抑制 Ca2+流入，导致 [Ca2+]i 在血管平滑肌细胞和随后的外周血管舒张中减少，具有降压作用。
T5120	Rhamnose 6-Deoxyhexopyranose,L-鼠李糖,6-Deoxy-L-mannose,alpha-L-Rhamnose	Calcium Channel; Endogenous Metabolite	Membrane transporter/Ion channel; Metabolism
	alpha-L-Rhamnose (6-Deoxy-L-mannose) 是存在植物和细菌中的一种单糖。Rhamnose- 免疫原连接物能被用于免疫疗法。Rhamnose 能通过胞外途径穿过上皮细胞，能够作为肠吸收的标志。
TN1065	Hirsutine	Apoptosis	Apoptosis
	Hirsutine 是一种来自钩藤的吲哚生物碱，可诱导细胞凋亡，是一种登革热病毒抑制剂，且毒性低。它具有抗癌、心脏保护、抗高血压、抗心律失常和血管舒张活性。
T4S1422	Praeruptorin E 白花前胡素 E,白花前胡素E	Others; Calcium Channel	Membrane transporter/Ion channel; Metabolism; Others
	Praeruptorin E 是白花前胡中的一种主要成分，是钙拮抗剂，pD2′值为 5.2。
T6S2140	β-Anhydroicaritin Anhydroicaritin,Beta-Anhydroicaritin,脱水淫羊藿素	MMP; Others; TNF; Interleukin	Apoptosis; Immunology/Inflammation; Others; Proteases/Proteasome
	β-Anhydroicaritin 是从乳香提取的一种天然产物，具有重要的生物学和药理学作用，如抗骨质疏松症，雌激素调节和抗肿瘤特性。它改善牙周组织的降解，抑制糖尿病大鼠 TNF-α 和 MMP-3 的合成和分泌。它抑制细胞内 Ca2+的升高，并显著降低 iNOS 蛋白的表达。
T37687	Cyclic ADP-ribose ammonium	Others	Others
	Cyclic ADP-ribose ammonium (cADPR ammonium) is a powerful calcium mobilization second messenger synthesized from NAD+ by an ADP-ribosyl cyclase. It primarily raises cytosolic calcium levels through Ryanodine receptor-mediated release from the endoplasmic reticulum, while also facilitating extracellular influx through the opening of TRPM2 channels [1][2][3].
T19253	Cyclic ADP-ribose cADPR	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Cyclic ADP-ribose (cADPR) is an effective calcium mobilization second messenger, which is synthesized from NAD + by ADP-ribosyl cyclase. Cyclic ADP-ribose mainly increases cytosolic calcium through Ryanodine receptor-mediated endoplasmic reticulum release
T82753	Celangulin
	Celangulin是一种从Celastrus angulatus中提取的天然杀虫成分，该化合物通过激活细胞质膜上的钙通道来增加细胞内Ca2+浓度，并能激活内质网钙通道。
TN2511	Britannilactone diacetate 1,6-O,O-Diacetylbritannilactone	IL Receptor; PARP; ROS; MAPK; Caspase; JAK; JNK; STAT	Angiogenesis; Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Immunology/Inflammation; JAK/STAT signaling; MAPK; Proteases/Proteasome; Stem Cells
	1,6-O,O-Diacetylbritannilactone(OODBL) has anti-inflammatory activity, it has a potential therapeutic efficacy on inflammatory diseases especially allergic airway disease as a lead compound. OODBL has anti-asthmatic activity, it reduces leukotriene C4 pro
TN4624	Nantenine	Others	Others
	Nantenine is an acetylcholinesterase inhibitor, it functions as an effective antagonist against a wide range of MDMA-induced effects in mice. Nantenine has anticonvulsant effect, which seems attributable to its stimulation and the resultant decrease of Ca
TN2534	1-Hydroxy-2,3,5-trimethoxyxanthone	IκB/IKK; Calcium Channel; NOS; 5-HT Receptor; COX	GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience; NF-κB
	1-Hydroxy-2,3,5-trimethoxyxanthone (HM-1) has vasodilator action ,which involves both an endothelium-dependent mechanism involving NO and an endothelium-independent mechanism by inhibiting Ca(2+) influx through L-type voltage-operated Ca(2+) channels; a minor contribution to the effects of HM-1 may be related to inhibition of the protein kinase C-mediated release of intracellular Ca(2+) stores. HM-1,at the concentration of 1 ug/mL, can effectively inhibit the osteoclast differentiation in a co-c...
T37219	N-Palmitoyl Glycine	Others	Others
	The acyl amides are a family of endogenous lipids that act as potent modulators of pain and inflammation. The best characterized members of this family are the arachidonoyl amides, which includes N-arachidonoyl ethanolamide (AEA; anandamide). N-palmitoyl glycine (PalGly) contains an 18-carbon saturated fatty acid that is amide-linked to glycine and is structurally similar to the phospholipid-derived N-acyl ethanolamines. Endogenously produced in rat skin and spinal cord, PalGly is present in 100...

天然产物

Cat.No: TN1121

Target: Apoptosis, cAMP, Anti-infection, Calcium Channel, Antibacterial

Cat.No: T8118

Synonym: Kanamycin B,卡那霉素,卡那霉素 B

Target: Antibacterial, Antibiotic

Cat.No: T23735

Synonym: An-Co-A4,AnCoA-4,An Co A4,AnCoA4

Target: Calcium Channel

Cat.No: TN1154

Synonym: 6-Methoxyluteolin,泽兰黄酮,6-甲氧基藤黄菌素

Target: Calcium Channel, Histamine Receptor

Cat.No: TN1136

Synonym: 原花青素 A1,Proanthocyanidin A1,原花色素A1

Target: LDL, Calcium Channel, PKC

Cat.No: T5S0890

Synonym: Neriostene,Folinerin,Foliandrin,欧夹竹桃苷

Target: Apoptosis, ATPase, Potassium Channel, Sodium Channel

Cat.No: TN2322

Target: Calcium Channel, PAFR

Cat.No: T5120

Synonym: 6-Deoxyhexopyranose,L-鼠李糖,6-Deoxy-L-mannose,alpha-L-Rhamnose

Target: Calcium Channel, Endogenous Metabolite

Cat.No: TN1065

Target: Apoptosis

Cat.No: T4S1422

Synonym: 白花前胡素 E,白花前胡素E

Target: Others, Calcium Channel

β-Anhydroicaritin

Cat.No: T6S2140

Synonym: Anhydroicaritin,Beta-Anhydroicaritin,脱水淫羊藿素

Target: MMP, Others, TNF, Interleukin

Cyclic ADP-ribose ammonium

Cat.No: T37687

Target: Others

Cyclic ADP-ribose

Cat.No: T19253

Synonym: cADPR

Target: Calcium Channel

Cat.No: T82753

Britannilactone diacetate

Cat.No: TN2511

Synonym: 1,6-O,O-Diacetylbritannilactone

Target: IL Receptor, PARP, ROS, MAPK, Caspase, JAK, JNK, STAT

Cat.No: TN4624

Target: Others

1-Hydroxy-2,3,5-trimethoxyxanthone

Cat.No: TN2534

Target: IκB/IKK, Calcium Channel, NOS, 5-HT Receptor, COX

N-Palmitoyl Glycine

Cat.No: T37219

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02521	HIST3H2A Protein, Human, Recombinant histone cluster 3, H2a,MGC3165	Human	E. coli
	Histones are a complex family of highly conserved basic proteins responsible for packaging chromosomal DNA into nucleosomes. There are subtype diversities: H1, H2A, H2B, and H3 or H4. It has become more and more evident that histone modifications are key players in the regulation of chromatin states and dynamics as well as in gene expression. Therefore, histone modifications and the enzymatic machinery that set them are crucial regulators that can control cellular proliferation, differentiation,...
TMPH-02324	SLC39A6 Protein, Human, Recombinant (His) Solute carrier family 39 member 6,Zinc transporter ZIP6,Estr...	Human	Baculovirus Insect Cells
	May act as a zinc-influx transporter. SLC39A6 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with C-6xHis tag. The predicted molecular weight is 35.0 kDa and the accession number is Q13433.
TMPH-02551	CD20 Protein, Mouse, Recombinant (His) Membrane-spanning 4-domains subfamily A member 1,CD20,B-lymp...	Mouse	P. pastoris (Yeast)
	B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR. CD20 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 22.3 kDa and the accession number is P19437.
TMPH-00344	CD20 Protein, Canine, Recombinant (His & Myc) MS4A1,Membrane-spanning 4-domains subfamily A member 1,CD20,...	Canine	E. coli
	B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR. CD20 Protein, Canine, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 17.4 kDa and the accession number ...
TMPH-02835	PDGFD Protein, Mouse, Recombinant (His & SUMO) Platelet-derived growth factor D,Pdgfd,Spinal cord-derived g...	Mouse	E. coli
	Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing. Has oncogenic potential and can induce tumor formation. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including inf...
TMPH-03035	M-myrmeciitoxin-Mp2b Protein, Myrmecia pilosula, Recombinant (GST & His) DELTA-myrtoxin-Mp1a B chain,Pilosin-3 subunit b,M-myrmeciito...	Myrmecia pilosula	Baculovirus Insect Cells
	Heterodimer protein that may serve both defensive (pain-inducing) and predatory (insecticidal) roles. Has membrane-disrupting activity and shows induction of non-specific calcium influx into cells,. Shows broad-spectrum activity against a diverse range of bacteria, and cell lines, as well as hemolytic activity (EC(50)=2.18 uM). In vivo, shows moderate insecticidal activity against D.melanogaster and potent anthelmintic activity against the veterinary nematode H.contortus. In addition, intraplant...
TMPH-00780	CACNA1C Protein, Guinea Pig, Recombinant (His) CACNA1C,CACNL1A1,CACH2,CACN2,Voltage-dependent L-type calciu...	Guinea pig	E. coli
	Pore-forming, alpha-1C subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents. Mediates influx of calcium ions into the cytoplasm, and thereby triggers calcium release from the sarcoplasm. Plays an important role in excitation-contraction coupling in the heart. Required for normal heart development and normal regulation of heart rhythm. Required for normal contraction of smooth muscle cells in blood vessels and in the intestine. Essential for normal blood pressur...
TMPH-00743	PhoP Protein, E. coli, Recombinant (HEK293, His & Myc) Transcriptional regulatory protein PhoP,phoP	E. coli	HEK293 Cells
	Member of the two-component regulatory system PhoP/PhoQ involved in adaptation to low Mg(2+) environments and the control of acid resistance genes. In low periplasmic Mg(2+), PhoQ phosphorylates PhoP, resulting in the expression of PhoP-activated genes (PAG) and repression of PhoP-repressed genes (PRG). In high periplasmic Mg(2+), PhoQ dephosphorylates phospho-PhoP, resulting in the repression of PAG and may lead to expression of some PRG. Mediates magnesium influx to the cytosol by activation o...
TMPJ-00011	CXCL2 Protein, Mouse, Recombinant Gro-beta,GRO β,GROB,melanoma growth stimulatory activity bet...	Mouse	E. coli
	C-X-C motif chemokine 2 (CXCL2,MIP-2) belongs to the intercrine alpha (chemokine CxC) family. It was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. The expression of mouse MIP-2 is stimulated by endotoxin. The mouse MIP-2 shares approximately 63% aa sequence identity with murine KC, another mouse alpha chemokine, which is induced by PDGF. It has been suggested that mouse KC and MIP-2 are the homologs of the hum...
TMPH-02347	Influenza A H1N1 (strain A/USA:Phila/1935) Matrix protein 2 (His) Matrix protein 2,Proton channel protein M2,M	H1N1	E. coli
	Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry. After attaching to the cell surface, the virion enters the cell by endocytosis. Acidification of the endosome triggers M2 ion channel activity. The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins ...
TMPJ-00666	CLIC2 Protein, Human, Recombinant (His) CLIC2,XAP121,Chloride Intracellular Channel Protein 2	Human	E. coli
	Chloride Intracellular Channel Protein 2 (CLIC2) is a critical component of all living cells; it regulatescellular traffic of Chloride ion and it can be inserted into membranes anf form chloride ion channels. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions, channel activity depends on the pH. CLIC2 is involved in regulating membrane potential and organic solute transport. CLIC2 modulates the activity of RYR2 and inhibits Calcium influx. CLIC2 can be d...
TMPH-02348	Influenza A H1N1 (strain A/Puerto Rico/8/1934) Matrix protein 2 (His & Myc) Matrix protein 2,M,Proton channel protein M2	H1N1	E. coli
	Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry. After attaching to the cell surface, the virion enters the cell by endocytosis. Acidification of the endosome triggers M2 ion channel activity. The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins ...
TMPJ-00741	PTH Protein, Human, Recombinant (His) Parathyroid hormone,Parathyrin,PTH,Parathormone	Human	HEK293 Cells
	Parathyroid hormone (PTH) is a critical hormone in the regulation of Ca++ homeostasis. Parathyroid hormone is the most important endocrine regulator of calcium and phosphorus concentration in extracellular fluid. This hormone is secreted from cells of the parathyroid glands and finds its major target cells in bone and kidney. Another hormone, parathyroid hormone-related protein, binds to the same receptor as parathyroid hormone and has major effects on development. Like most other protein hormon...
TMPH-01694	MLKL Protein, Human, Recombinant (E. coli, His) MLKL,Mixed lineage kinase domain-like protein	Human	E. coli
	Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Does not have protein kinase activity. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. In addition to TNF-induced necroptosis, necroptosis can also take place in the nucleus in response to orthomyxoviruses infection: following activation by ZB...
TMPY-01605	STIM1 Protein, Human, Recombinant (His) stromal interaction molecule 1,TAM1,GOK,STRMK,IMD10,D11S4896...	Human	HEK293 Cells
	Stromal interaction molecule 1, also known as STIM1 and GOK, is a cell membrane, a single-pass type I membrane protein and a endoplasmic reticulum membrane protein. STIM1 / GOK is ubiquitously expressed in various human primary cells and tumor cell lines. It contains one EF-hand domain and one SAM (sterile alpha motif) domain. STIM1 / GOK plays a role in mediating Ca2+influx following depletion of intracellular Ca2+stores. It acts as Ca2+sensor in the endoplasmic reticulum via its EF-hand domain...
TMPY-01875	SCGN Protein, Human, Recombinant (His) SEGN,SECRET,DJ501N12.8,CALBL,secretagogin, EF-hand calcium b...	Human	E. coli
	Secretagogin, also known as SCGN, is a secreted protein that is detectable in human serum after ischemic neuronal damage. It is a recently described calcium-binding protein. Secretagogin / SCGN is expressed at high levels in the pancreatic islets of Langerhans and to a much lesser extent in the gastrointestinal tract (stomach, small intestine and colon), the adrenal medulla and cortex and the thyroid C-cells. In the brain, the expression of Secretagogin / SCGN is restricted to distinct subtypes ...
TMPY-01909	Elafin Protein, Human, Recombinant (His) WAP3,ESI,peptidase inhibitor 3,SKALP,cementoin,MGC13613,WFDC...	Human	HEK293 Cells
	Elafin, also known as Elastase-specific inhibitor, Peptidase inhibitor 3, Protease inhibitor WAP3, Skin-derived antileukoproteinase, WAP four-disulfide core domain protein 14, PI3, WAP3 and WFDC14, is a secreted protein that contains one WAP domain. Elafin / PI3 consists of two domains: the transglutaminase substrate domain (cementoin moiety) and the elastase inhibitor domain. The transglutaminase substrate domain at the N-terminus serves as an anchor to localize elafin covalently to specific si...
TMPY-02510	HIST2H2BE Protein, Human, Recombinant MGC129734,H2BGL105,H2B.1,histone cluster 2, H2be,H2B,H2BFQ,G...	Human	E. coli
	Histones are a complex family of highly conserved basic proteins responsible for packaging chromosomal DNA into nucleosomes. Histone proteins exhibit two levels of diversity: 1. evolutionary diversity between species and 2. subtype diversity in a class(H1, H2A, H2B, H3 or H4) within a species. It has become more and more evident that histone modifications are key players in the regulation of chromatin states and dynamics as well as in gene expression. Therefore, histone modifications and the enz...
TMPH-02217	SMARCA4 Protein, Human, Recombinant (His) Transcription activator BRG1,Protein brahma homolog 1,SWI/SN...	Human	P. pastoris (Yeast)
	Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating the calcium-dependent release of a repressor compl...
TMPH-02631	PRKN Protein, Mouse, Recombinant (GST) E3 ubiquitin-protein ligase parkin,Prkn,Parkin RBR E3 ubiqui...	Mouse	E. coli
	Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Substrates include SYT11 and VDAC1. Other substrates are BCL2, CCNE1, GPR37, RHOT1/MIRO1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, MIRO1 and AIMP2. Mediates monoubiquitination as well as 'Lys-6', 'Lys-11', 'Lys-48'-linked and 'Lys-63'-linked polyubiquitination of substrates depending on the context. Participates in the removal and/or det...
TMPH-01263	PRKN Protein, Human, Recombinant (His & SUMO) PRKN,Parkin RBR E3 ubiquitin-protein ligase,E3 ubiquitin-pro...	Human	E. coli
	Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Substrates include SYT11 and VDAC1. Other substrates are BCL2, CCNE1, GPR37, RHOT1/MIRO1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, MIRO1 and AIMP2. Mediates monoubiquitination as well as 'Lys-6', 'Lys-11', 'Lys-48'-linked and 'Lys-63'-linked polyubiquitination of substrates depending on the context. Participates in the removal and/or det...

重组蛋白

HIST3H2A Protein, Human, Recombinant

Cat.No: TMPY-02521

Species: Human

Expression System: E. coli

SLC39A6 Protein, Human, Recombinant (His)

Cat.No: TMPH-02324

Species: Human

Expression System: Baculovirus Insect Cells

CD20 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02551

Species: Mouse

Expression System: P. pastoris (Yeast)

CD20 Protein, Canine, Recombinant (His & Myc)

Cat.No: TMPH-00344

Species: Canine

Expression System: E. coli

PDGFD Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02835

Species: Mouse

Expression System: E. coli

M-myrmeciitoxin-Mp2b Protein, Myrmecia pilosula, Recombinant (GST & His)

Cat.No: TMPH-03035

Species: Myrmecia pilosula

Expression System: Baculovirus Insect Cells

CACNA1C Protein, Guinea Pig, Recombinant (His)

Cat.No: TMPH-00780

Species: Guinea pig

Expression System: E. coli

PhoP Protein, E. coli, Recombinant (HEK293, His & Myc)

Cat.No: TMPH-00743

Species: E. coli

Expression System: HEK293 Cells

CXCL2 Protein, Mouse, Recombinant

Cat.No: TMPJ-00011

Species: Mouse

Expression System: E. coli

Influenza A H1N1 (strain A/USA:Phila/1935) Matrix protein 2 (His)

Cat.No: TMPH-02347

Species: H1N1

Expression System: E. coli

CLIC2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00666

Species: Human

Expression System: E. coli

Influenza A H1N1 (strain A/Puerto Rico/8/1934) Matrix protein 2 (His & Myc)

Cat.No: TMPH-02348

Species: H1N1

Expression System: E. coli

PTH Protein, Human, Recombinant (His)

Cat.No: TMPJ-00741

Species: Human

Expression System: HEK293 Cells

MLKL Protein, Human, Recombinant (E. coli, His)

Cat.No: TMPH-01694

Species: Human

Expression System: E. coli

STIM1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01605

Species: Human

Expression System: HEK293 Cells

SCGN Protein, Human, Recombinant (His)

Cat.No: TMPY-01875

Species: Human

Expression System: E. coli

Elafin Protein, Human, Recombinant (His)

Cat.No: TMPY-01909

Species: Human

Expression System: HEK293 Cells

HIST2H2BE Protein, Human, Recombinant

Cat.No: TMPY-02510

Species: Human

Expression System: E. coli

SMARCA4 Protein, Human, Recombinant (His)

Cat.No: TMPH-02217

Species: Human

Expression System: P. pastoris (Yeast)

PRKN Protein, Mouse, Recombinant (GST)

Cat.No: TMPH-02631

Species: Mouse

Expression System: E. coli

PRKN Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01263

Species: Human

Expression System: E. coli

Cat. No.	Product Name	Target	Signaling Pathways
TMID-0262	Lidocaine-d10 (N,N-diethyl-d10)
	Lidocaine-d10 (N,N-diethyl-d10) 是 Lidocaine 的氘代化合物。Lidocaine 的 CAS 号为 137-58-6。Lidocaine是一种酰胺衍生物，抑制涉及复杂电压和依赖性的钠通道，可用于研究室性心律失常。它通过调节 miR-145 表达和进一步抑制MEK/ERK和NF-κB信号通路来减少胃癌细胞的生长，迁移和侵袭。
T71303	Flufenamic Acid-d4
	Flufenamic acid-d4 is intended for use as an internal standard for the quantification of flufenamic acid by GC- or LC-MS. Flufenamic acid is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (IC50s = 3 and 9.3 µM for human COX-1 and COX-2, respectively). Flufenamic acid inhibits TNF-α-induced increases in COX-2 levels and NF-κB activation in HT-29 colon cancer cells in a concentration-dependent manner. It inhibits calcium influx induced by fMLP or A23187 in human polymorphonuclear...

同位素标记化合物

Lidocaine-d10 (N,N-diethyl-d10)

Cat.No: TMID-0262

Flufenamic Acid-d4

Cat.No: T71303

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