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Search Results for " indoxyl sulfate-d5 potassium "
Targets Recommended: Others

2

抑制剂 & 化合物

1

同位素标记化合物

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Cat. No. Product Name Target Signaling Pathways
T70312 AZ1366

Others Others
AZ1366 is a potent tankyrase inhibitor that enhances irinotecan activity in tumors that exhibit elevated tankyrase and irinotecan resistance. Combination AZ1366 and irinotecan achieved greater anti-tumor effects compared to monotherapy. Activity was limited to CRC explants that displayed irinotecan resistance and increased protein levels of tankyrase and NuMA.
T32161 Indoxyl sulfate

Others Others
Indoxyl sulfate is a metabolite of tryptophan, showing adverse effects on bones and the central nervous system, having been most frequently implicated as a contributor to renal disease progression and vascular disease

化合物

AZ1366
Cat.No: T70312
Synonym:
Target: Others
Indoxyl sulfate
Cat.No: T32161
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
T70313 Indoxyl Sulfate-d5 potassium salt

Indoxyl sulfate-d5 is intended for use as an internal standard for the quantification of indoxyl sulfate by GC- or LC-MS. Indoxyl sulfate is a uremic toxin and a metabolite of tryptophan. It is formed via sulfation of indole, an intermediate generated from tryptophan by intestinal bacteria, by the sulfotransferase (SULT) isoform 1A1 variant 2 (SULT1A1*2) in the liver. Indoxyl sulfate activates the aryl hydrocarbon receptor (AhR) in HepG2 40/6 hepatoma cells (EC50 = 12.1 nM in a reporter assay). ...

同位素标记化合物

Indoxyl Sulfate-d5 potassium salt
Cat.No: T70313
Synonym:
Target:
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