Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-02740 |
IL-31R alpha Protein, Mouse, Recombinant (His)
ZcytoR17,Interleukin-31 receptor subunit alpha,Nove... |
Mouse | E. coli |
Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity. Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1. Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro. IL-31R alpha Protein, Mouse, Recombinant (His) is expressed in E. coli expression... | |||
TMPK-00617 |
IL-13 Protein, Human, Recombinant (His & Avi)
NC30,ALRH,IL13,MGC116786,MGC116789,P600,MGC116788,B... |
Human | HEK293 Cells |
Interleukin-13 (IL-13) is a monomeric 17 kDa immunoregulatory cytokine that plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is secreted by several helper T cell subsets, NK cells, mast cells, eosinophils, basophils, and visceral smooth muscle cells. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. Positively regulates IL31RA expression in macro... |