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Search Results for " igg2a "

14

抑制剂 & 化合物

1

天然产物

11

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T78337	Mouse IgG2a kappa, Isotype Control
	Mouse IgG2a kappa, Isotype Control 是鼠源IIgG2a kappa 抗体的同型抗体。
T76908	Anumigilimab
	Anumigilimab (CSL-324) 是一种人源化IgG2a 单抗，靶向人粒细胞集落刺激因子 (G-CSF) 受体。Anumigilimab 可用于炎症部位中性粒细胞数量增加的研究。
T78268	Anti-Mouse NK1.1 Antibody (PK136)
	Anti-Mouse NK1.1 Antibody (PK136) 是鼠源靶向 NK1.1的IgG2a类抗体，可消除外周血、脾脏和肺组织中的NK1.1和NK1.1NKT细胞，抑制 NK1.1 信号传导，可用于研究心肺衰竭。
T81755	Mouse lgG2a (D265A) kappa, Isotype Control
	Mouse lgG2a (D265A) kappa, Isotype Control 为 mouse lgG2a (D265A) 的鼠源单克隆同型对照抗体。
T80620	Anti-Mouse CD19 Antibody (1D3)
	Anti-MouseCD19Antibody (1D3) 为针对小鼠CD19的IgG2a亚型单克隆抗体。
T78260	Anti-Mouse CD8a Antibody (53-6.7)
	Anti-MouseCD8aAntibody为针对小鼠CD8a的IgG2a亚型单克隆抗体，其宿主为大鼠。
T80583	Anti-Mouse 4-1BB Antibody (3H3)
	Anti-Mouse4-1BBAntibody为针对小鼠4-1BB的IgG2a类抗体抑制剂，源自宿主Rat。
T76835	Tositumomab
	Tositumomab 是一种靶向CD20抗原的小鼠IgG2a lambda 单克隆抗体，CD20抗原存在于正常和恶性B 淋巴细胞表面。
T80585	Anti-Mouse GM-CSF Antibody (MP1-22E9)	c-Fms	Tyrosine Kinase/Adaptors
	Anti-MouseGM-CSFAntibody 为特异性针对小鼠GM-CSF的IgG2a类免疫球蛋白抗体，由大鼠血清中提取。
T80597	Dafsolimab SPV-T3a
	Dafsolimab (SPV-T3a)为IgG2a型小鼠单克隆抗体，主要针对CD3。通过调节及激活CD3/T细胞受体复合物，Dafsolimab能够诱导细胞凋亡，常用于移植物抗宿主病（GVHD）的研究领域。
T76841	Enlimomab
	Enlimomab (BI-RR 0001) 是一种针对人 ICAM-1的小鼠 IgG2a 单抗，可抑制白细胞粘附到血管内皮，从而减少白细胞外渗漏和炎症性组织损伤。Enlimomab 具有抗炎作用，可用于中风研究。
T82260	Grisnilimab WT1
	Grisnilimab (WT1)为IgG2a亚型的单克隆抗体（抗CD7），与Wilms' tumor发病相关的肿瘤抑制因子。该抗体能够调控多个靶基因的转录活性，并可能涉及RNA的转录后修饰过程。
T76680	Fremanezumab
	Fremanezumab (TEV-48125) 是一种人源化IgG2a 单克隆抗体，可选择性且有效地与降钙素基因相关肽 (CGRP) 结合。CGRP 是一种 37 个氨基酸的神经肽，参与偏头痛的中枢和外周病理生理事件。Fremanezumab 具有用于慢性偏头痛研究的潜力。
T76920	Bectumomab
	Bectumomab (IMMU-LL 2) 是一种针对人CD22(抗原) 的人源化IgG2a 单抗。Bectumomab 也是一种抗淋巴瘤抗体片段。Bectumomab 可与锝 99 (Tc99m LL2 Fab) 联合用于成像。此外，Bectumomab 能够检查复发性或新诊断的非霍奇金淋巴瘤 (NHL) 的分期，并在放射免疫研究 (RIT) 前评估靶向性。

化合物

Mouse IgG2a kappa, Isotype Control

Cat.No: T78337

Cat.No: T76908

Anti-Mouse NK1.1 Antibody (PK136)

Cat.No: T78268

Mouse lgG2a (D265A) kappa, Isotype Control

Cat.No: T81755

Anti-Mouse CD19 Antibody (1D3)

Cat.No: T80620

Anti-Mouse CD8a Antibody (53-6.7)

Cat.No: T78260

Anti-Mouse 4-1BB Antibody (3H3)

Cat.No: T80583

Cat.No: T76835

Anti-Mouse GM-CSF Antibody (MP1-22E9)

Cat.No: T80585

Target: c-Fms

Cat.No: T80597

Synonym: SPV-T3a

Cat.No: T76841

Cat.No: T82260

Synonym: WT1

Cat.No: T76680

Cat.No: T76920

Cat. No.	Product Name	Target	Signaling Pathways
T12500	Platycoside E Platycodin E,桔梗苷E	Others	Others
	Platycoside E (Platycodin E) 是一种桔梗皂苷元型皂苷，从桔梗的根中分离获得，能够促进 ovalbumin 免疫小鼠中血清 OVA 特异性IgG2a 和IgG2b 抗体的产生。它具有溶血活性和佐剂潜力。

天然产物

Cat.No: T12500

Synonym: Platycodin E,桔梗苷E

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02694	IgG2a Protein, Mouse, Recombinant IgG2a-Fc,Igh-1,1816O9Rik	Mouse	HEK293 Cells
	IgG2a Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.4 kDa and the accession number is P01863.
TMPY-05188	IgG2a Protein, Mouse, Recombinant, Biotinylated Igh-1,IgG2a-Fc,1816O9Rik	Mouse	HEK293 Cells
	IgG2a Protein, Mouse, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.4 kDa and the accession number is P01863.
TMPJ-00893	IgG2a Protein, Rat, Recombinant Ig γ-2A chain C region,Ig gamma-2A chain C...	Rat	HEK293 Cells
	Immunoglobulin G (IgG) is a type of antibody composed of four peptide chains—two identical heavy chains and two identical light chains arranged in a Y-shape typical of antibody monomers.There are four IgG subclasses (IgG1, 2, 3, and 4) in humans, named in order of their abundance in serum. The IgG2a isotype was able to interact very efficiently with FcgammaR, and share approximately 64-78% amino acid sequence identity with IgG1 and IgG2b in the heavy chain constant region domains, CH1, CH2 and C...
TMPJ-01182	SIRP alpha Protein, Mouse, Recombinant (MIgG2a) SIRP,CD172 Antigen-Like Family Member A,SIRPA,MFR,Signal-Reg...	Mouse	HEK293 Cells
	SIRPα is a type I transmembrane glycoprotein.It contains two Ig-like C1-type domains and one Ig-like V-type domain. Mouse SIRP alpha ECD shares 61%, 75%, 62%, 61%, and 59% aa sequence identity with human, rat, equine, bovine, and porcine SIRP alpha, respectively.SIRPα can express in various tissues, mainly on brain and myeloid cells, including macrophages, neutrophils, dendritic and Langerhans cells. It also can detect in neurons, smooth muscle and endothelial cells. SIRPA is an immunoglobulin-l...
TMPY-00105	Recombinant Protein G		E. coli
	Protein G is a bacterial cell wall protein expressed at the cell surface of certain group C and group G Streptococcal strains. It has affinity for both Fab- and Fc-fragments of human IgG by independent and separate binding sites. Binding to the Fc region of immunoglobulins from several species by a non-immune mechanism exhibits great affinity for almost all mammalian immunoglobulin G (IgG) classes, including all human IgG subclasses (IgG1, IgG2, IgG3 and IgG4) and also rabbit, mouse, and goat Ig...
TMPK-00624	CD200R1/CRTR2 Protein, Human, Recombinant (hFc) MOX2R,CRTR2,CD200R,HCRTR2,CD200 R1,MOX2 receptor,OX2R,CD200 ...	Human	HEK293 Cells
	CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cell surface receptor, CD200R, expressed on cells of the myeloid and T cell lineage. A recent report focused attention on a family of CD200Rs, but concluded that only one member used CD200 as its ligand. CD200R1/CRTR2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 53....
TMPK-00622	CD200R1/CRTR2 Protein, Human, Recombinant (His & Avi) OX2R,CD200R,MOX2R,CD200 R1,CRTR2,HCRTR2,CD200 receptor 1,MOX...	Human	HEK293 Cells
	CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cell surface receptor, CD200R, expressed on cells of the myeloid and T cell lineage. A recent report focused attention on a family of CD200Rs, but concluded that only one member used CD200 as its ligand. CD200R1/CRTR2 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular wei...
TMPK-01262	CD200R1/CRTR2 Protein, Cynomolgus, Recombinant (His) CD200 receptor 1,OX2R,MOX2R,CD200 R1,MOX2 receptor,CD200R,HC...	Cynomolgus	HEK293 Cells
	CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cell surface receptor, CD200R, expressed on cells of the myeloid and T cell lineage. A recent report focused attention on a family of CD200Rs, but concluded that only one member used CD200 as its ligand. CD200R1/CRTR2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight i...
TMPK-00623	CD200R1/CRTR2 Protein, Human, Recombinant (His & Avi), Biotinylated CRTR2,MOX2R,OX2R,CD200 R1,HCRTR2,CD200 receptor 1,MOX2 recep...	Human	HEK293 Cells
	CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cell surface receptor, CD200R, expressed on cells of the myeloid and T cell lineage. A recent report focused attention on a family of CD200Rs, but concluded that only one member used CD200 as its ligand. CD200R1/CRTR2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted...
TMPY-04964	Recombinant Protein A, HRP conjugate
	Protein A is surface protein originally found in the cell wall of the bacteria Staphylococcusaureus. It is encoded by the spa gene and its regulation is controlled by DNA topology, cellular osmolarity, and a two component system called ArlS-ArlR. Protein A binds the Fc region of various mammalian IgG subclasses including: Human IgG1, IgG2, IgG3 (weakly), IgG4 Mouse IgG1 (weakly), IgG2a, IgG2b, IgG3 SPA also binds IgG from monkey, rabbit, pig, guinea pig, dog, rat and cat. It also weakly binds to...
TMPJ-00070	IL-18 Protein, Human, Recombinant (His) GIF,IL-1 γ,白细胞介素,Iboctadekin,Interleukin-18,Interferon γ-ind...	Human	HEK293 Cells
	Interleukin-18 is a secreted protein and it belongs to the IL-1 family. IL-18 is a proinflammatory cytokine and produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL-4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. After...

重组蛋白

IgG2a Protein, Mouse, Recombinant

Cat.No: TMPY-02694

Species: Mouse

Expression System: HEK293 Cells

IgG2a Protein, Mouse, Recombinant, Biotinylated

Cat.No: TMPY-05188

Species: Mouse

Expression System: HEK293 Cells

IgG2a Protein, Rat, Recombinant

Cat.No: TMPJ-00893

Species: Rat

Expression System: HEK293 Cells

SIRP alpha Protein, Mouse, Recombinant (MIgG2a)

Cat.No: TMPJ-01182

Species: Mouse

Expression System: HEK293 Cells

Recombinant Protein G

Cat.No: TMPY-00105

Expression System: E. coli

CD200R1/CRTR2 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00624

Species: Human

Expression System: HEK293 Cells

CD200R1/CRTR2 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00622

Species: Human

Expression System: HEK293 Cells

CD200R1/CRTR2 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-01262

Species: Cynomolgus

Expression System: HEK293 Cells

CD200R1/CRTR2 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00623

Species: Human

Expression System: HEK293 Cells

Recombinant Protein A, HRP conjugate

Cat.No: TMPY-04964

Expression System:

IL-18 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00070

Species: Human

Expression System: HEK293 Cells

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