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Search Results for " ifosfamide "

Targets Recommended: DNA Alkylator/Crosslinker DNA/RNA Synthesis

抑制剂 & 化合物

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T1055	Ifosfamide NSC109724,Isophosphamide,异环磷酰胺	DNA Alkylator/Crosslinker; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Ifosfamide (NSC-109724) 是一种烷化剂，具有抗肿瘤活性。它烷基化并形成 DNA 交联，从而防止 DNA 链分离和 DNA 复制。它是一种前药，必须通过肝微粒体酶的羟基化来激活。
T25723	L-Ifosfamide (+)-Ifosfamide	Others	Others
	L-Ifosfamide is nitrogen mustard, a chemotherapeutic antineoplastic, and more precisely an alkylating agent structural analog of cyclophosphamide with respect to which presents some differences regard to the antitumor activity and spectrum.
T4350	Palifosfamide ZIO-201,Isophosphamide mustard,帕利伐米,Isophosphoramide mustard	DNA Alkylator/Crosslinker; DNA Alkylation; Drug Metabolite	DNA Damage/DNA Repair; Metabolism
	Palifosfamide (Isophosphamide mustard) 是一种新 DNA 烷化剂，是异环磷酰胺的活性代谢物，。它在体外肉瘤细胞系中具有广泛的活性，具有抗癌活性。
T29851	Aldoifosfamide UNII-S1JX147O5E,Mitoxana,Ifex	Others	Others
	Aldoifosfamide is a metabolite of ifosfamide. Ifosfamide (also marketed as Mitoxana and Ifex) is a nitrogen mustard alkylating agent used in the treatment of cancer. It is sometimes abbreviated 'IFO''.
T71500	Palifosfamide tromethamine IPM tromethamine,Isophosphoramide mustard tromethamine,ZIO-201 tromethamine,Isophosphoramide mustard tromethamine ; IPM tromethamine ; ZIO-201 tromethamine	Others	Others
	Palifosfamide (tromethamine) 是一种具有潜在抗肿瘤活性的合成烷基化剂。作为异环磷酰胺 (ifosfamide) 稳定的活性代谢物，Palifosfamide (tromethamine) 通过GC 碱基对不可逆地烷基化和交联DNA，导致了DNA 复制的抑制，并导致细胞死亡。与异环磷酰胺相比，Palifosfamide (tromethamine)的毒性较小。
T83317	4-Hydroperoxyifosfamide	Others	Others
	4-Hydroperoxyifosfamide是一种能穿透血脑屏障的抗癌化合物。
T1414	Sodium 2-mercaptoethanesulfonate Mitexan,美司那,美司钠,Uromitexan,Mesna,Mesnum,Mesnex	Others	Others
	Sodium 2-mercaptoethanesulfonate (Uromitexan) 是一种抗氧化剂，具有细胞保护作用。它可用于减轻由环磷酰胺引起的出血性膀胱炎。它广泛用作抗化学疗法毒性的全身保护剂。

化合物

Ifosfamide

Cat.No: T1055

Synonym: NSC109724,Isophosphamide,异环磷酰胺

Target: DNA Alkylator/Crosslinker, DNA/RNA Synthesis

L-Ifosfamide

Cat.No: T25723

Synonym: (+)-Ifosfamide

Target: Others

Palifosfamide

Cat.No: T4350

Synonym: ZIO-201,Isophosphamide mustard,帕利伐米,Isophosphoramide mustard

Target: DNA Alkylator/Crosslinker, DNA Alkylation, Drug Metabolite

Aldoifosfamide

Cat.No: T29851

Synonym: UNII-S1JX147O5E,Mitoxana,Ifex

Target: Others

Palifosfamide tromethamine

Cat.No: T71500

Synonym: IPM tromethamine,Isophosphoramide mustard tromethamine,ZIO-201 tromethamine,Isophosphoramide mustard tromethamine ; IPM tromethamine ; ZIO-201 tromethamine

Target: Others

4-Hydroperoxyifosfamide

Cat.No: T83317

Synonym:

Target: Others

Sodium 2-mercaptoethanesulfonate

Cat.No: T1414

Synonym: Mitexan,美司那,美司钠,Uromitexan,Mesna,Mesnum,Mesnex

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02299	ALDH3A1 Protein, Human, Recombinant (His) ALDHIII,aldehyde dehydrogenase 3 family, member A1,ALDH3	Human	Baculovirus Insect Cells
	Aldehyde dehydrogenase 3A1 (ALDH3A1) is a metabolic enzyme that catalyzes the oxidation of various aldehydes. Certain types of epithelial tissues in mammals, especially those continually exposed to environmental stress (e.g., corneal epithelium), express ALDH3A1 at high levels and its abundance in such tissues is perceived to help to maintain cellular homeostasis under conditions of oxidative stress. Metabolic as well as non-metabolic roles for ALDH3A1 have been associated with its mediated resi...

重组蛋白

ALDH3A1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02299

Species: Human

Expression System: Baculovirus Insect Cells

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