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Cat. No. | Product Name | Target | Signaling Pathways |
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TMAZ-0324A |
Anti-IZUMO1 Monoclonal Antibody-APC
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Anti-IZUMO1 Monoclonal Antibody-APC is a Biotin-conjugated humanized rabbit antibody targeting IZUMO1. Anti-IZUMO1 Monoclonal Antibody-APC can be used in FACS. | |||
TMAZ-0324P |
Anti-IZUMO1 Monoclonal Antibody-PE
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Anti-IZUMO1 Monoclonal Antibody-PE is a Biotin-conjugated humanized rabbit antibody targeting IZUMO1. Anti-IZUMO1 Monoclonal Antibody-PE can be used in FACS. | |||
TMAZ-0324A4 |
Anti-IZUMO1 Monoclonal Antibody-AF488
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Anti-IZUMO1 Monoclonal Antibody-AF488 is a Biotin-conjugated humanized rabbit antibody targeting IZUMO1. Anti-IZUMO1 Monoclonal Antibody-AF488 can be used in FACS. | |||
TMAZ-0324B |
Anti-IZUMO1 Monoclonal Antibody-Biotin
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Anti-IZUMO1 Monoclonal Antibody-Biotin is a Biotin-conjugated humanized rabbit antibody targeting IZUMO1. Anti-IZUMO1 Monoclonal Antibody-Biotin can be used in FACS. | |||
TMAZ-0324A5 |
Anti-IZUMO1 Monoclonal Antibody-AF555
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Anti-IZUMO1 Monoclonal Antibody-AF555 is a Biotin-conjugated humanized rabbit antibody targeting IZUMO1. Anti-IZUMO1 Monoclonal Antibody-AF555 can be used in FACS. | |||
TMAZ-0324A6 |
Anti-IZUMO1 Monoclonal Antibody-AF647
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Anti-IZUMO1 Monoclonal Antibody-AF647 is a Biotin-conjugated humanized rabbit antibody targeting IZUMO1. Anti-IZUMO1 Monoclonal Antibody-AF647 can be used in FACS. |
Cat. No. | Product Name | Species | Expression System |
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TMPH-01567 |
IZUMO1 Protein, Human, Recombinant (His & Myc)
Izumo sperm-egg fusion protein 1,IZUMO... |
Human | E. coli |
Essential sperm cell-surface protein required for fertilization by acting as a ligand for IZUMO1R/JUNO receptor on egg. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. | |||
TMPY-03220 |
IZUMO1 Protein, Human, Recombinant (His)
izumo sperm-egg fusion 1,IZUMO |
Human | HEK293 Cells |
Izumo is a sperm membrane protein that plays a key role in the fusion in the mouse. It has an Immunoglobulin (Ig) domain and an N-terminal domain for which neither the functions nor homologous sequences are known. Up to now, there four members has an N-terminal domain with significant homology to the N-terminal domain of Izumo. We call this domain the Izumo domain. The four proteins are Izumo 1, 2, 3, and 4. Izumo domain possesses the ability to form dimers, whereas the transmembrane domain or t... | |||
TMPK-00585 |
FOLR4/Juno Protein, Human, Recombinant (His)
Folate receptor 4,FR-δ,Folbp3,FR-delta,Izumo1 |
Human | HEK293 Cells |
Izumo1 is the only essential sperm-egg fusion protein currently known on mammalian sperm, and its egg receptor (Juno; formerly Folr4) was recently discovered. Male knockout mice for Izumo1 and female knockout mice for Juno are both healthy but sterile. Here, both sperm-egg binding proteins are shown to be evolving under positive selection. Juno's presence in mammals alone, suggesting a recent mammalian-specific duplication and neofunctionalization of the ancestral folate receptor. FOLR4/Juno Pro... | |||
TMPK-01171 |
FOLR4/Juno Protein, Mouse, Recombinant (His)
Juno,FOLR4, LOC390243,Folate receptor 4,FR δ,FR-delta,Folbp3... |
Mouse | HEK293 Cells |
Izumo1 is the only essential sperm-egg fusion protein currently known on mammalian sperm, and its egg receptor (Juno; formerly Folr4) was recently discovered. Male knockout mice for Izumo1 and female knockout mice for Juno are both healthy but sterile. Here, both sperm-egg binding proteins are shown to be evolving under positive selection. Juno's presence in mammals alone, suggesting a recent mammalian-specific duplication and neofunctionalization of the ancestral folate receptor. FOLR4/Juno Pro... | |||
TMPJ-01190 |
SPESP1 Protein, Human, Recombinant (His)
Sperm Equatorial Segment Protein 1,Glycosylated 38 ... |
Human | HEK293 Cells |
Sperm Equatorial Segment Protein 1 (SPESP1) is a member of the SPESP1 family. SPESP1 is highly expressed in the testis, where it is localized to the acrosome of postmeiotic stages of spermiogenesis; it is expressed at lower levels in the placenta and fetal lung. SPESP1 is involved in the multicellular organisimal development. Disruption of SPESP1 leads to abnormal distribution of sperm proteins resulting in a detached membrane from the equatorial segment and less fertile sperm. SPESP1 may intera... |