Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T68249 |
IRC-083927 HCl
|
Others | Others |
IRC-083927 HCl is novel and potent microtubule inhibitor with potential anticancer activity. IRC-083927 inhibits the tubulin polymerization by a binding to the colchicine site. IRC-083927 inhibits in vitro cell growth of human cancer cell lines in the low nanomolar range. More interesting, it remains highly active against cell lines resistant to microtubule-interacting agents (taxanes, Vinca alkaloids, or epothilones). Chronic oral treatment with IRC-083927 (5 mg/kg) inhibits the growth of two h... | |||
T68246 |
IRC-083927 free base
|
Others | Others |
IRC-083927 free base is novel and potent microtubule inhibitor with potential anticancer activity. |