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Cat. No.	Product Name	Target	Signaling Pathways
T68321	AS1940477	Others	Others
	AS1940477 is p38 MAPK inhibitor. AS1940477 inhibited the enzymatic activity of recombinant p38α and β isoforms but showed no effect against other 100 protein kinases including p38γ and δ isoforms. In human peripheral blood mononuclear cells, AS1940477 inhibited lipopolysaccharide (LPS)- or phytohemagglutinin A (PHA)-induced production of proinflammatory cytokines, including TNFα, IL-1β, and IL-6 at low concentrations (LPS/TNFα, IC(50)=0.45n M; PHA/TNFα, IC(50)=0.40 nM). In addition, equivalent c...
T71951	AS-1940477 hydrobromide	Others	Others
	AS-1940477 hydrobromide is a p38 mitogen-activated protein kinase (MAPK) inhibitor.