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Search Results for " il 6 "

Targets Recommended: Others

195

抑制剂 & 化合物

63

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化合物库

90

重组蛋白

12

同位素标记化合物

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Cat. No.	Product Name
L3800	NF-κB 通路分子库		729 compounds
	729 个 NF-κB 信号通路相关的小分子化合物的特有集合，用于高通量、高内涵筛选；
L7600	趋化因子抑制剂库		59 compounds
	59 种趋化因子或其受体抑制剂的独特集合，可用于高通量筛选和高内涵筛选；

化合物库

NF-κB 通路分子库

Cat.No: L3800

Compounds: 729

趋化因子抑制剂库

Cat.No: L7600

Compounds: 59

Cat. No.	Product Name	Target	Signaling Pathways
TP1422	Interleukin (IL)-6 Receptor	Others	Others
	Interleukin (IL)-6 Receptor 是一种肽，来源于白细胞介素6受体。
T8477	IQ-3	JNK	MAPK
	IQ3 是c-JNK 家族选择性抑制剂，对JNK3 的选择性更好。它对JNK1、JNK2 和 JNK3 的Kd 值分别为0.24 μM、0.29 μM 和 0.066 μM。
T9926	Omalizumab	Others	Others
	Omalizumab 是针对人免疫球蛋白 E 的重组人源化单克隆抗体(KD:0.393 nM)。它能够结合人 FcγRIIb 受体(KD:6.37 uM)。它对持续性过敏性哮喘具有潜在的研究价值。
T5110	IRAK inhibitor 6	IRAK	Immunology/Inflammation; NF-κB
	IRAK inhibitor 6 是白细胞介素-1受体相关激酶-4的抑制剂(IC50:160 nM)。
T8692	(Rac)-Benpyrine	TNF	Apoptosis
	(Rac)-Benpyrine 是一种有效且具有口服活性的 TNF-α 抑制剂，是Benpyrine 的外消旋体。它可研究TNF-α介导的炎症和自身免疫性疾病。
T6761	Ossirene AS101	IL Receptor; Caspase; Interleukin	Apoptosis; Immunology/Inflammation; Proteases/Proteasome
	Ossirene (AS101) 是一种免疫调节抑制剂，是一种新型 IL-1beta 转化酶抑制剂，可用于自身免疫性疾病和某些恶性肿瘤。它通过抑制IL-10消除 STAT3 的磷酸化，有效抑制Caspase-1。
T27695	JTE-607 JTE-607 dihydrochloride,JTE-607 HCl,甲氧番荔枝碱	Cysteine Protease	Proteases/Proteasome
	JTE-607 HCl 是高选择性的炎性细胞因子合成抑制剂，可保护小鼠免受内毒素休克。它作用于 LPS 刺激的人 PBMC，抑制TNF-α(IC50:11 nM)、IL-1β(IC50:5.9 nM)、IL-6(IC50:8.8 nM)、IL-8(IC50:7.3 nM)和IL-10(IC50:9.1 nM)。
T40423	L48H37	Others	Others
	L48H37是Curcumin的一个化学稳定类似物。它对髓系分化蛋白2 (MD2) 表现出强效的抑制性质，作为一个特异性抑制剂。其机制包括抑制LPS-TLR4/MD2的相互作用和信号传导。L48H37主要用于脓血症和肺损伤研究[1]。
T6927	Pamapimod R1503,帕吡莫德,Ro4402257	p38 MAPK; Autophagy	Autophagy; MAPK
	Pamapimod (R1503) 是一种新型的选择性 p38 丝裂原活化蛋白激酶抑制剂，对于p38α和p38β的IC50分别为 14 nM 和 480 nM，Ki 分别为 1.3 nM 和 120 nM，对 p38δ 或 p38γ 亚型没有活性，可研究类风湿关节炎和其他自身免疫性疾病。
T8705	BOT-64	IκB/IKK	NF-κB
	BOT-64 是一种 IKK-2 抑制剂，靶向激酶激活环结构域中的 Ser177 和/或 Ser181 残基。BOT-64 是一种可渗透细胞的苯并恶硫醇化合物。
T14943	CGP60474	VEGFR; CDK; PKC	Angiogenesis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
	CGP60474 是一种高效的抗内毒素药物，抑制细胞周期蛋白依赖激酶(CDK) ，抑制 CDK1/B、CDK2/E、CDK2/a、CDK4/D、CDK5/p25、CDK7/H 和 CDK9/T 的IC50分别为 26、3、4、216、10、200 和 13 nM。它是选择性和 ATP 竞争性PKC 抑制剂。
T11793	KY-05009	Wnt/beta-catenin	Cytoskeletal Signaling; Stem Cells
	KY-05009 是 ATP 竞争性的、有效的 TNIK 抑制剂，Ki 为 100 nM。KY-05009抑制人肺腺癌细胞中 TGF-β1 诱导的上皮-间质转化。KY-05009 还抑制TNIK 的蛋白表达和Wnt 靶基因的转录活性，并诱导癌细胞凋亡，显示抗癌活性。
T4602	Hydrocortisone hemisuccinate Hydrocortisone 21-he,氢化可的松琥珀酸酯,hydrocortisone 21-hemisuccinate*free acid,Hydrocortisone 21-hemisuccinate	Glucocorticoid Receptor; Others; Interleukin	Endocrinology/Hormones; Immunology/Inflammation; Others
	Hydrocortisone hemisuccinate (hydrocortisone 21-hemisuccinate*free acid) 是糖皮质激素，是口服有活性的甾体抗炎剂。它能够降低IL-6(IC50:6.7 μM)、IL-3(IC50:21.4 μM)的生物活性，可用于研究溃疡性结肠炎。
T6950	PNU-120596 NSC 216666	AChR	Neuroscience
	PNU-120596 (NSC-216666) 是一种选择性α7 nAChR 阳性变构调节剂，EC50为 216 nM，可用于精神病和神经疾病的研究。
T2036	6-OAU GTPL5846	GPR	Endocrinology/Hormones; GPCR/G Protein
	6-OAU (GTPL5846) 是 GPR84 的替代激动剂，在 Gqi5 嵌合体存在的情况下，在 HEK293 细胞中激活人 GPR84，在 PI 测定中 EC50 为 105 nM。
T6404	Bazedoxifene hydrochloride Bazedoxifene HCl,盐酸巴多昔芬,TSE-424	Estrogen Receptor/ERR; Estrogen/progestogen Receptor	Endocrinology/Hormones
	Bazedoxifene hydrochloride (TSE-424) 是一种 IL-6/GP130蛋白相互作用抑制剂，可用于胰腺癌的研究。它也是一种有口服活性的，能透过血脑屏障的，非甾体、选择性的雌激素受体调节剂 (SERM)，对 ERα 和 ERβ 作用的 IC50值分别为 26 nM 和 99 nM，可用于研究骨质疏松症。
T16501	PF-3644022	p38 MAPK; Serine Protease; MAPK	MAPK; Proteases/Proteasome
	PF-3644022 是可口服的，具有 ATP 竞争性的MAPKAPK2 (MK2)选择性抑制剂，IC50为 5.2 nM，Ki 为 3 nM。它有效抑制 TNFα 的产生并具有抗炎作用，还抑制 MK3 和 p38 调节/激活激酶，IC50分别为 53 和 5.0 nM。
TQ0181	Resatorvid CLI-095,TAK-242,瑞沙托维	TNF; TLR; Autophagy; Interleukin	Apoptosis; Autophagy; Immunology/Inflammation
	Resatorvid (TAK-242) 是一种 Toll 样受体 4 (TLR4) 的抑制剂，具有选择性。Resatorvid 直接与 Cys747 结合，阻止 TLR4 与 TIRAP 结合，从而阻止下游信号转导。Resatorvid 具有抗肿瘤活性、抗炎活性和神经保护作用。
TMAZ-0053P	Anti-IL6R Monoclonal Antibody-PE

TMAZ-0053B	Anti-IL6R Monoclonal Antibody-Biotin

T35389	Sarilumab (anti-IL-6Rα)	IL Receptor	Immunology/Inflammation
	Sarilumab (anti-IL-6Rα)是人源anti-IL-6Rα单克隆抗体，与膜结合的和可溶性的IL-6Rα以高亲和力结合。MW: 144.13 KD。
TMAZ-0043A	Anti-IL6ST Monoclonal Antibody-APC

TMAZ-0043P	Anti-IL6ST Monoclonal Antibody-PE

TMAZ-0053A	Anti-IL6R Monoclonal Antibody-APC

TMAZ-0043B	Anti-IL6ST Monoclonal Antibody-Biotin

T2544	Bazedoxifene acetate 醋酸巴多昔芬,WAY-TES 424,TSE 424,WAY-140424	Estrogen Receptor/ERR; Estrogen/progestogen Receptor	Endocrinology/Hormones
	Bazedoxifene acetate (WAY-TES 424) 是一种非甾体的、有口服活性的、选择性的雌激素受体调节剂，能够作用于 ERα (IC50:26 nM) 和 ERβ (IC50:99 nM) ，可用于研究骨质疏松症。它也是一种IL-6/GP130蛋白相互作用抑制剂，可用于研究胰腺癌。
TMAZ-0053A5	Anti-IL6R Monoclonal Antibody-AF555

TMAZ-0053A6	Anti-IL6R Monoclonal Antibody-AF647

TMAZ-0053A4	Anti-IL6R Monoclonal Antibody-AF488

TMAZ-0043A6	Anti-IL6ST Monoclonal Antibody-AF647

TMAZ-0043A4	Anti-IL6ST Monoclonal Antibody-AF488

TMAZ-0043A5	Anti-IL6ST Monoclonal Antibody-AF555

T15769	LMT-28	IL Receptor	Immunology/Inflammation
	LMT-28 是一种 IL-6 抑制剂，选择性抑制 IL-6 诱导的 gp130、STAT3 和 JAK2 磷酸化。
T76722	Sarilumab REGN-88,SAR-153191	IL Receptor	Immunology/Inflammation
	Sarilumab（SAR-153191）是一种有效的白细胞介素-6 IL-6 受体拮抗剂，是人源免疫球蛋白 G1 单克隆抗体。 Sarilumab 抑制由 IL-6 介导的信号传导，可减少炎症。Sarilumab 可用于预防和治疗类风湿关节炎。
T4403	AX-024 hydrochloride AX-024 HCl	IL Receptor; TNF; COX; IFNAR; Interleukin	Apoptosis; Immunology/Inflammation; Neuroscience
	AX-024 hydrochloride (AX-024 HCl) 是一种细胞因子释放抑制剂，可强烈抑制 IL-6、TNFα、IFN-γ、IL-10 和 IL-17A 的产生。它是口服可利用的 TCR-Nck 相互作用抑制剂，可选择性地抑制 TCR 触发的 T 细胞活化。它通过靶向 SH3结构域调节细胞信号传导，具有低毒、高效和高选择性的特点。
T9581	ARRY-797 ARRY-371797	IL Receptor; p38 MAPK	Immunology/Inflammation; MAPK
	ARRY-797 (ARRY-371797) 是一种有效的选择性 p38α 抑制剂，可抑制 LPS 诱导的 IL-6。
T9911	Tocilizumab	Interleukin	Immunology/Inflammation
	Tocilizumab 是抗人白细胞介素-6 受体 (IL-6R) 的中和抗体，能够阻碍 IL-6 与 IL-6R 的结合，进而抑制经典和反式信号。它可用于研究类风湿性关节炎，对重症 COVID-19 冠状病毒病方面的研究具有显著效果。
T75174	Anti-inflammatory agent 42	IL Receptor; TNF	Apoptosis; Immunology/Inflammation
	Anti-inflammatory agent 42 具有抗炎活性，抑制 LPS 刺激的巨噬细胞 TNF-α 和 IL-6 的表达。
T28958	TG6-129 TG6 129	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	TG6-129 是有效的EP2受体选择性拮抗剂，可降低 butaprost 诱导的 P388D1 巨噬细胞中炎症因子的表达。
T17107	TMC353121	IL Receptor; TNF; RSV	Apoptosis; Immunology/Inflammation; Microbiology/Virology
	TMC353121 是呼吸道合胞病毒 (RSV) 融合抑制剂，具有抗 RSV 活性，抑制炎性细胞因子 TNF-α、IL-6 和 IL-1β 以及趋化因子、KC、IP-10、MCP 和 MIP1-α 的产生。
T7606	Guanosine 5'-diphosphate disodium salt 5'-二磷酸鸟苷二钠,5'-GDP-Na2,鸟苷-5'-二磷酸二钠盐	Endogenous Metabolite	Metabolism
	Guanosine 5'-diphosphate disodium salt (5'-GDP-Na2) 是一种核苷二磷酸。它是一种潜在的铁动员剂，能够阻断铁调素-铁转运蛋白相互作用，也可以调节白 IL-6/stat-3 途径。
T60739L	Y13g dihydrochloride Y13g 2HCl(T60739 Free base)	IL Receptor; AChE	Immunology/Inflammation; Neuroscience
	Y13g dihydrochloride 是白细胞介素 6 (IL-6) 和乙酰胆碱酯酶 (AChE)的有效抑制剂（这两个靶点阿尔茨海默症 (AD) 进展的有关）。Y13g dihydrochloride 逆转 STZ 诱导的记忆缺陷，并表现出与正常动物相似的组织病理学。
T11079	NMI 8739 n-docosahexaenoyl dopamine,Dha-DA conjugate	Dopamine Receptor	GPCR/G Protein; Neuroscience
	NMI 8739 (n-docosahexaenoyl dopamine) 是 D2 自身受体的激动剂。 NMI 8739 减少 NO 的产生并引起 CCL-20、MCP-1 和 IL-6 释放的浓度依赖性抑制。
T125076	Hispidulin 7-glucuronide	IL Receptor	Immunology/Inflammation
	Hispidulin 7-glucuronide是一种可从槲皮的叶中提取到的黄酮类化合物，具有潜在的抗炎活性，可抑制IL-6的释放。
T76978	Siltuximab CNTO-328	IL Receptor	Immunology/Inflammation
	Siltuximab（CNTO-328）是一种靶向 IL-6 且具有抗肿瘤活性的单克隆抗体，可用于研究巨大淋巴结增生症 (MCD) 和 COVID-19。
T27026	CJ-13,610 CJ 13610,CJ-13610	Lipoxygenase	Metabolism
	CJ-13,610 是一种具有口服活性的非氧化还原型 5-脂氧合酶 (5-LOX) 抑制剂。 CJ-13,610 抑制白三烯 B4 的生物合成并调节巨噬细胞中 IL-6 mRNA 的表达。
T67924	ABzOH	Others	Others
	ABzOH 是一种苯甲酸衍生物，结构类似于阿司匹林等非甾体抗炎药，具有抗炎、抗肿瘤和抗增殖作用。ABzOH 不仅可以抑制肿瘤坏死因子- α (TNF-a)、白细胞介素-1β (IL-1β)和白细胞介素-6 (IL-6)等促炎细胞因子的表达还对乳腺癌、肺癌和胰腺癌具有抑制作用。
T37113	Z62954982 ZINC08010136	Rho	Cell Cycle/Checkpoint
	Z62954982 (ZINC08010136) 是一种具有选择性的 Rac1 抑制剂，神经突的生长和分支变得迟钝。Z62954982 抑制 Rac1 激活，减少肺动脉中的增殖、p38 磷酸化和 IL-6 水平。
T63067	Emprumapimod PF-07265803,ARRY-371797	p38 MAPK	MAPK
	Emprumapimod (PF-07265803) 是一种具有口服活性和特异性的丝裂原活化蛋白激酶 p38α MAPK 抑制剂，抑制 LPS 诱导产生的 IL-6 ，可用于研究 LMNA 基因引起的扩张型心肌病。
T64359	Anti-inflammatory agent 36	Immunology/Inflammation related	Immunology/Inflammation
	Anti-inflammatory agent 36 是一种抗炎剂。它对LPS 诱导的RAW 264.7细胞释放TNF-a 和IL-6具有剂量依赖性的抑制作用，IC50分别为3.69uM 和3.68uM。

化合物

Interleukin (IL)-6 Receptor

Cat.No: TP1422

Target: Others

Cat.No: T8477

Target: JNK

Cat.No: T9926

Target: Others

IRAK inhibitor 6

Cat.No: T5110

Target: IRAK

(Rac)-Benpyrine

Cat.No: T8692

Target: TNF

Cat.No: T6761

Synonym: AS101

Target: IL Receptor, Caspase, Interleukin

Cat.No: T27695

Synonym: JTE-607 dihydrochloride,JTE-607 HCl,甲氧番荔枝碱

Target: Cysteine Protease

Cat.No: T40423

Target: Others

Cat.No: T6927

Synonym: R1503,帕吡莫德,Ro4402257

Target: p38 MAPK, Autophagy

Cat.No: T8705

Target: IκB/IKK

Cat.No: T14943

Target: VEGFR, CDK, PKC

Cat.No: T11793

Target: Wnt/beta-catenin

Hydrocortisone hemisuccinate

Cat.No: T4602

Synonym: Hydrocortisone 21-he,氢化可的松琥珀酸酯,hydrocortisone 21-hemisuccinate*free acid,Hydrocortisone 21-hemisuccinate

Target: Glucocorticoid Receptor, Others, Interleukin

Cat.No: T6950

Synonym: NSC 216666

Target: AChR

Cat.No: T2036

Synonym: GTPL5846

Target: GPR

Bazedoxifene hydrochloride

Cat.No: T6404

Synonym: Bazedoxifene HCl,盐酸巴多昔芬,TSE-424

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor

Cat.No: T16501

Target: p38 MAPK, Serine Protease, MAPK

Cat.No: TQ0181

Synonym: CLI-095,TAK-242,瑞沙托维

Target: TNF, TLR, Autophagy, Interleukin

Anti-IL6R Monoclonal Antibody-PE

Cat.No: TMAZ-0053P

Anti-IL6R Monoclonal Antibody-Biotin

Cat.No: TMAZ-0053B

Sarilumab (anti-IL-6Rα)

Cat.No: T35389

Target: IL Receptor

Anti-IL6ST Monoclonal Antibody-APC

Cat.No: TMAZ-0043A

Anti-IL6ST Monoclonal Antibody-PE

Cat.No: TMAZ-0043P

Anti-IL6R Monoclonal Antibody-APC

Cat.No: TMAZ-0053A

Anti-IL6ST Monoclonal Antibody-Biotin

Cat.No: TMAZ-0043B

Bazedoxifene acetate

Cat.No: T2544

Synonym: 醋酸巴多昔芬,WAY-TES 424,TSE 424,WAY-140424

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor

Anti-IL6R Monoclonal Antibody-AF555

Cat.No: TMAZ-0053A5

Anti-IL6R Monoclonal Antibody-AF647

Cat.No: TMAZ-0053A6

Anti-IL6R Monoclonal Antibody-AF488

Cat.No: TMAZ-0053A4

Anti-IL6ST Monoclonal Antibody-AF647

Cat.No: TMAZ-0043A6

Anti-IL6ST Monoclonal Antibody-AF488

Cat.No: TMAZ-0043A4

Anti-IL6ST Monoclonal Antibody-AF555

Cat.No: TMAZ-0043A5

Cat.No: T15769

Target: IL Receptor

Cat.No: T76722

Synonym: REGN-88,SAR-153191

Target: IL Receptor

AX-024 hydrochloride

Cat.No: T4403

Synonym: AX-024 HCl

Target: IL Receptor, TNF, COX, IFNAR, Interleukin

Cat.No: T9581

Synonym: ARRY-371797

Target: IL Receptor, p38 MAPK

Cat.No: T9911

Target: Interleukin

Anti-inflammatory agent 42

Cat.No: T75174

Target: IL Receptor, TNF

Cat.No: T28958

Synonym: TG6 129

Target: Prostaglandin Receptor

Cat.No: T17107

Target: IL Receptor, TNF, RSV

Guanosine 5'-diphosphate disodium salt

Cat.No: T7606

Synonym: 5'-二磷酸鸟苷二钠,5'-GDP-Na2,鸟苷-5'-二磷酸二钠盐

Target: Endogenous Metabolite

Y13g dihydrochloride

Cat.No: T60739L

Synonym: Y13g 2HCl(T60739 Free base)

Target: IL Receptor, AChE

Cat.No: T11079

Synonym: n-docosahexaenoyl dopamine,Dha-DA conjugate

Target: Dopamine Receptor

Hispidulin 7-glucuronide

Cat.No: T125076

Target: IL Receptor

Cat.No: T76978

Synonym: CNTO-328

Target: IL Receptor

Cat.No: T27026

Synonym: CJ 13610,CJ-13610

Target: Lipoxygenase

Cat.No: T67924

Target: Others

Cat.No: T37113

Synonym: ZINC08010136

Target: Rho

Cat.No: T63067

Synonym: PF-07265803,ARRY-371797

Target: p38 MAPK

Anti-inflammatory agent 36

Cat.No: T64359

Target: Immunology/Inflammation related

Cat. No.	Product Name	Target	Signaling Pathways
TN6739	Angoline 6-Methoxyldihydrochelerythrine	IL Receptor; STAT	Immunology/Inflammation; JAK/STAT signaling; Stem Cells
	Angoline (6-Methoxyldihydrochelerythrine) 是选择性 IL6/STAT3信号通路的抑制剂，IC50为 11.56 μM。它抑制 STAT3 磷酸化及其靶基因表达，并抑制癌细胞增殖。
TN6722	Terminolic acid 2α,6β,23-trihydroxyl oleanolic acid	Antibacterial	Microbiology/Virology
	Terminolic acid (2α,6β,23-trihydroxyl oleanolic acid) 是一种从 Combretum racemosum 中分离得到的五环三萜糖苷，可通过与 IL-1β 和 IL-6 的受体活性位点结合抑制促炎细胞因子，并通过与 IL-4 受体结合位点结合增强抗炎细胞因子。它还表现出适度的抗菌活性。
T2893	Muscone 3-Methylcyclopentadecanone,Methylexaltone,麝香酮	MMP; TNF; NF-κB; NOD-like Receptor (NLR); P-gp; Interleukin	Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience; NF-κB; Proteases/Proteasome
	Muscone (3-Methylcyclopentadecanone) 是中药麝香的一种主要活性单体。它抑制NF-κB 和NLRP3炎性小体的活化，显著降低炎性细胞因子水平，并最终改善心脏功能和存活率。
TN1520	Isoforskolin Coleonol B	IL Receptor; TNF	Apoptosis; Immunology/Inflammation
	Isoforskolin 源自毛喉鞘蕊花，可减少人单核白细胞中 TNF-α、IL-1β、IL-6 和 IL-8 的分泌。Isoforskolin 可用于治疗莱姆关节炎的研究。
T40660	Kansuinine B	IL Receptor; SARS-CoV	Immunology/Inflammation; Microbiology/Virology
	Kansuinine B 抑制由 IL-6 诱导的 Stat3 活化。 Kansuinine B 具有抗病毒活性，可用于 COVID-19 研究。
TN6778	Umbelliprenin 伞形花醚,7-[[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrienyl]oxy]-2H-1-benzopyran-2-oneUmbelliprenin	IL Receptor	Immunology/Inflammation
	Umbelliprenin (7-[[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrienyl]oxy]-2H-1-benzopyran-2-oneUmbelliprenin) 可减轻神经性疼痛，并降低血清 IL-6 水平和氧化应激。
TN6393	fulvotomentoside A	Others	Others
	fulvotomentoside A 可降低肠道中 IL-6 和 IL-17A 的过表达，并显着增加调节性 T 细胞特异性转录因子 Foxp3 的表达。这可能是Ful 改善肠道炎症的机制之一。
TQ0218	Deoxyandrographolide 去氧穿心莲内酯,14-deoxyandrographolide	IL Receptor; TNF	Apoptosis; Immunology/Inflammation
	Deoxyandrographolide (14-deoxyandrographolide) 抑制 LPS 诱导的 iNOS mRNA 水平升高以及促炎症介质 TNF-α 和 IL-6 的产生。它增强 NGF 诱导的神经突起生长。
T1048	Estradiol 雌二醇,E2,17β-Estradiol,17β-Oestradiol,β-Estradiol	Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	Estradiol (E2) 是一种天然的类固醇性激素，对于女性生育能力和第二性征的维持至关重要。Estradiol 通过雌激素受体 β (ERβ) 上调 IL-6 表达。
TN4379	Kansuinine A	IL Receptor; STAT; Interleukin	Immunology/Inflammation; JAK/STAT signaling; Stem Cells
	Kansuinine A 对IL-6 诱导的 Stat3激活有作用。Kansuinine A 显示出抗病毒和抗肿瘤活性。
TN1154	Nepetin 6-Methoxyluteolin,泽兰黄酮,6-甲氧基藤黄菌素	Calcium Channel; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience
	Nepetin (6-Methoxyluteolin) 是一种分离自Eupatorium ballotaefoliumHBK 中的天然类黄酮，具有有效的抗炎作用。它在 ARPE-19 细胞中能够抑制IL-6(IC50:4.43 μM) 、IL-8 (IC50:43.42 μM) 、MCP-1 (IC50:4.17 μM) 的分泌。
T4S0145	Corylifol A Corylinin,补骨脂异黄酮A	hCE; STAT; UGT	JAK/STAT signaling; Metabolism; Stem Cells
	Corylifol A (Corylinin) 是补骨脂中的一种天然产物，可抑制IL-6 诱导的STAT3激活和磷酸化，IC50值为0.81 μM。
T6S1597	Mulberroside A 桑皮苷 A,桑皮苷A	TNF; Tyrosinase; Interleukin	Apoptosis; Immunology/Inflammation; Proteases/Proteasome
	Mulberroside A 是桑中的一种主要活性成分，可降低TNF-α、IL-1β和IL-6的表达，抑制 NALP3、caspase-1 和 NF-κB 的激活以及 ERK、JNK 和 p38 的磷酸化。它抑制蘑菇酪氨酸酶，具有抗炎和抗细胞凋亡作用。
T2791	Pectolinarin 柳穿鱼叶苷,大蓟苷	Apoptosis; Others; NO Synthase; Prostaglandin Receptor; Interleukin	Apoptosis; GPCR/G Protein; Immunology/Inflammation; Others
	Pectolinarin 抑制 IL-6和 IL-8分泌以及 PGE2和 NO 产生，可通过抑制 PI3K/Akt 途径来抑制细胞增殖和炎症反应并诱导凋亡，具有抗炎活性。
T2932	Ginsenoside Rh1 Sanchinoside B2,人参皂苷 Rh1,人参皂苷Rh1,Prosapogenin A2,20(S)-Ginsenoside Rh1,Sanchinoside Rh1	IL Receptor; TNF; Endogenous Metabolite; PPAR; Interleukin	Apoptosis; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism
	Ginsenoside Rh1 (Sanchinoside B2) 是人参的一种主要成分，具有抗炎作用，抑制PPAR-γ，TNF-α，IL-6和IL-1β的表达。
T6S0139	Neobavaisoflavone	Apoptosis; DNA/RNA Synthesis	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Neobavaisoflavone 是一种从Psoralea corylifolia 的种子中分离出来的类黄酮。它具有抗炎，抗癌和抗氧化的作用。它在中至高浓度下可抑制 DNA 聚合酶，也可抑制血小板聚集。
T7210	Guanosine 5'-diphosphate GDP,鸟苷-5ˊ-二磷酸	Endogenous Metabolite	Metabolism
	Guanosine 5'-diphosphate (GDP) 是核苷二磷酸，是潜在的铁动员剂，能够阻断铁调素-铁转运蛋白相互作用并调节白细胞介素-6 (IL-6)/stat-3 途径。
T5S1981	alpha-Cyperone (+)-α-Cyperone,α-香附酮,α-Cyperone	Others; Endogenous Metabolite	Metabolism; Others
	alpha-Cyperone (α-Cyperone) 与 IL-6, Cox-2, Cdc42, Nck-2, Rac1 的表达下调相关,从而能够抑制炎症反应。
T3809	Liriope muscari baily saponins C	Others	Others
	Liriope muscari baily saponins C 是一种L. muscari (Decne.) Baily 的主要活性成分。它已被作为肿瘤转移候选药物进行研究。它具有很强的抗炎、免疫药理和心脏保护作用。
T3816	Velutin	NF-κB; HIF/HIF Prolyl-Hydroxylase	Chromatin/Epigenetic; Metabolism; NF-κB
	Velutin 是一种苷元，提取自槲寄生中，能够抑制黑色素生物合成。它利用 NF-κB 途径减少破骨细胞分化和下调 HIF-1α。
T3662	Eleutheroside E	NF-κB	NF-κB
	Eleutheroside E 是刺五加的重要成分，具有抗炎，保护缺血心脏的功能。
Fr14115	α-Terpineol Terpineol,α-松油醇	IL Receptor; Anti-infection; Antibacterial	Immunology/Inflammation; Microbiology/Virology
	α-Terpineol (Terpineol) 是从蓝桉中分离出来的，对须癣毛癣菌有抗真菌活性，对牙周病和致龋菌有抗菌活性。它还具有抗惊厥和抗炎活性。
T2758	Madecassic acid 6-Deoxy-L-Galactose,羟基积雪草酸,L-Fucose,Brahmic acid,L-fucopyranose	Others; TNF; COX; NO Synthase; Interleukin	Apoptosis; Immunology/Inflammation; Neuroscience; Others
	Madecassic acid (L-fucopyranose) 是分离自积雪草的一种天然产物，抑制iNOS、COX-2、TNF-α、IL-1beta 和IL-6，可通过在 RAW 264.7 巨噬细胞中下调NF-κB 激活而具有抗炎作用。
T8033	Sodium Thiocyanate	Others; Reactive Oxygen Species; Interleukin	Immunology/Inflammation; Metabolism; NF-κB; Others
	Sodium thiocyanate 能够减少促炎细胞因子 IL-6水平，并增强抗炎细胞因子 IL-10水平，并显著减少 ROS 形成。
TN1410	Asperulosidic acid ASPA,车叶草苷酸	ERK; NF-κB	MAPK; NF-κB
	Asperulosidic acid (ASPA) 是从白花蛇舌草药中提取的一种环烯醚萜苷，具有抗肿瘤、抗氧化和抗炎作用。它通过抑制 NF-κB 和丝裂原活化蛋白激酶信号通路抑制炎性细胞因子释放发挥抗炎作用。
T0798	Triamcinolone Fluoxyprednisolone,曲安西龙,Aristocort,Rodinolone	Glucocorticoid Receptor; COX	Endocrinology/Hormones; Immunology/Inflammation; Neuroscience
	Triamcinolone (Aristocort) 是一种皮质类固醇激素受体激动剂，也是一种合成的长效糖皮质激素，具有抗炎活性。
T5S0167	Atractylenolide I 白术内酯 I,白术内酯I；苍术内酯I	IL Receptor; TNF; TLR; JAK; STAT	Angiogenesis; Apoptosis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Stem Cells
	Atractylenolide I 是从白术根中得到的一种倍半萜烯，具有神经保护、抗过敏、抗炎和抗癌等多种生物活性。它是一种TLR4拮抗剂，在 A375 细胞中，能够降低JAK2和STAT3的磷酸化水平。
T8152	6-Demethoxytangeretin	MAPK; ALK	Angiogenesis; MAPK; Tyrosine Kinase/Adaptors
	6-Demethoxytangeretin 是一种从柑橘分离的黄酮。它能够促进 CRE 介导的转录 (与海马神经元的学习和记忆相关)。它具有抗炎和抗过敏作用，通过间变性淋巴瘤激酶和丝裂原活化蛋白激酶途径抑制人肥大细胞中 IL-6 的产生和基因表达。
T3926	Echinatin 刺甘草查尔酮,Retrochalcone	Free radical scavengers	oxidation-reduction
	Echinatin (Retrochalcone) 是分离自中草药甘草中，具有保肝和抗炎活性。在大鼠中，它可以被快速吸收和消除，并广泛分布，绝对生物利用度约为 6.81％。
TN5171	Tricetin	Apoptosis; Others; Nrf2	Apoptosis; Immunology/Inflammation; Others
	Tricetin 是一种从石榴中分离出的类黄酮。Tricetin 是 Keap1-Nrf2 蛋白相互作用（PPI）的强效竞争性抑制剂，通过激活 Nrf2/HO-1 信号通路和阻止线粒体依赖性细胞凋亡通路，保护帕金森病患免受 6-OHDA 诱导的神经毒性的影响。Tricetin 通过 Akt/GSK-1β途径抑制鼻咽癌的迁移和指示性蛋白酶早老素-1（PS-1）表达。Tricetin 抑制由Egr-1介导的氧化LDL 诱导的内皮炎症，保护大鼠软骨细胞免受IL-1β诱导的炎症和细胞凋亡。
TJS0338	4-Methylesculetin 4-Methyl-6,7-dihydroxycoumarin,6,7-二羟基-4-甲基香豆素,Methylesculetin,4-甲基七叶亭	Antioxidant; Glutathione Peroxidase	Metabolism; oxidation-reduction
	4-Methylesculetin (Methylesculetin) 是口服具有活力的天然香豆素衍生物，有抗氧化、抗炎特性。它可抑制myeloperoxidase 的特性，抑制 IL-6 的水平
T6S1315	Oroxylin A 千层纸素A,6-Methoxybaicalein,Baicalein 6-methyl ether	Virus Protease; HIF/HIF Prolyl-Hydroxylase; Autophagy	Autophagy; Chromatin/Epigenetic; Metabolism; Microbiology/Virology
	Oroxylin A (Baicalein 6-methyl ether) 是一种有活性的黄酮，具有较强的抗癌作用。
T3803	Specnuezhenide 特女贞苷,Nuzhenide,Nuezhenide	Others; NF-κB; Wnt/beta-catenin	Cytoskeletal Signaling; NF-κB; Others; Stem Cells
	Specnuezhenide (Nuezhenide) 是分离自女贞子的果实中。它可抑制 NF-κB 和 wnt/β-catenin 信号传导，进而抑制 IL-1β 诱导的软骨细胞炎症。它可在骨关节炎 (OA) 大鼠模型中发挥抗炎作用。
T3398	Icaritin Anhydroicaritin,去水淫羊藿黄素,Cycloicaritin	Apoptosis; JAK; STAT; Autophagy	Angiogenesis; Apoptosis; Autophagy; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
	Icaritin (Anhydroicaritin) 是Epimedium Genusis 的异戊二烯类黄酮衍生物，有效抑制 K562 细胞和原代 CML 细胞的增殖。它可以调节MAPK/ERK/JNK 和JAK2/STAT3/AKT 信号传导，并具有增强成骨的作用。
T4S2063	Tetrahydrocoptisine 人血草碱,STYLOPINE	ERK; p38 MAPK; NF-κB	MAPK; NF-κB
	Tetrahydrocoptisine (STYLOPINE) 具有抑制炎症的有效作用。它通过抑制 NF-κB 信号通路对 LPS 诱导的 ALI 具有保护作用，这可能涉及抑制肺部炎症过程。它具有胃保护活性，归因于减少 NO 产生和调节促炎细胞因子，抑制中性粒细胞积累和 NF-κB 表达。它是一种活性抗炎成分，通过下调 NF-κB 活化、磷酸化 ERK1/2 和磷酸化-p38MAPK 信号通路抑制 TNF-α、IL-6 和 NO 的产生。
T6S1049	Wilforine	ATPase	Membrane transporter/Ion channel
	Wilforine 是一倍半萜吡啶化合物，T. wilfordii 植物中的重要生物活性化合物，可有效治疗特发性肺纤维化。它具有抗炎和杀虫活性。
T4S1422	Praeruptorin E 白花前胡素 E,白花前胡素E	Others; Calcium Channel	Membrane transporter/Ion channel; Metabolism; Others
	Praeruptorin E 是白花前胡中的一种主要成分，是钙拮抗剂，pD2′值为 5.2。
T4115	Auraptene 橙皮油内酯,7-geranyloxycoumarin,橙皮油素	MMP; BACE	Neuroscience; Proteases/Proteasome
	Auraptene 是一种丰富的天然香叶氧基香豆素。它能够抑制基质金属蛋白酶 2 以及关键炎症因子，包括 IL-6，IL-8 和趋化因子 (C-C 基序) 配体-5 (CCL5）的分泌。
T2S0843	Negletein 黄芩素-7-甲醚,7-O-Methylbaicalein,Baicalein-7-methylether	IL Receptor; TNF; NOS; Interleukin	Apoptosis; Immunology/Inflammation
	Negletein (7-O-Methylbaicalein) 一种神经保护剂，可增强神经生长因子的作用并诱导 PC12 细胞中的神经突生长。它通过抑制TNF-α和IL-1β表现出抗炎活性，其 IC50值分别为 16.4 和 10.8 μM。它还具有抗菌、抗缺氧和抗阿尔茨海默病活性。
T6S1141	Ganoderic acid A 灵芝酸 A,灵芝酸A	Apoptosis; NF-κB; Endogenous Metabolite; Autophagy	Apoptosis; Autophagy; Metabolism; NF-κB
	Ganoderic acid A 能够抑制 JAK-STAT3信号通路，也能抑制细胞增殖，存活率和 ROS。它对人骨肉瘤 HOS 和MG-63细胞具有增殖抑制、凋亡和侵袭抑制作用。
T3744	Veratric acid Veratrumenoic acid,藜芦酸,3,4-Dimethoxybenzoic acid	Reactive Oxygen Species; COX	Immunology/Inflammation; Metabolism; Neuroscience; NF-κB
	Veratric acid (3,4-Dimethoxybenzoic acid) 是从蔬菜和水果中得到的一种可口服多酚，具有抗氧化、保护心血管和抗炎活性。当细胞受到 UVB 辐射时，它能够减少上调的 COX-2 表达，降低 PGE2 和 IL-6 水平。
T6S1917	Schisandrol B Gomisin A,TJN-101,Besigomsin,五味子醇乙,Gamma-Schisandrin,戈米辛A,Schizandrol B,Wuweizi alcohol-B	P450; Reactive Oxygen Species; Autophagy	Autophagy; Immunology/Inflammation; Metabolism; NF-κB
	Schisandrol B (Besigomsin) 是华中五味子的主要活性成分，具有保肝、抗炎、抗糖尿病和抗氧化的作用。它抑制活性氧的产生，也抑制 P-糖蛋白和CYP3A 的活性。
T5558	Chelidonic acid Jervaic acid,Jerva acid,白屈菜酸,γ-Pyrone-2,6-dicarboxylic acid	NF-κB; Caspase	Apoptosis; NF-κB; Proteases/Proteasome
	Chelidonic acid (Jervaic acid) 是从白屈菜中分到的酸类物质，用作温和的镇痛剂、抗菌剂和中枢神经系统镇静剂。它是谷氨酸脱羧酶抑制剂，Ki 值为 1.2 μM。它可能通过抑制 NF-κB 和caspase-1来降低 IL-6 的产生抗炎作用。
T2S2264	Linalool Linalol,(±)-Linalool,Phantol,沉香醇	Apoptosis; IL Receptor; TNF; Endogenous Metabolite; iGluR	Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience
	Linalool (Linalol) 是存在芫荽等植物中的单萜类天然产物，是竞争性NMDA 受体拮抗剂，具有抗肿瘤和抗心脏毒性的作用。它通过激活 Nrf2 诱导抗氧化防御和通过抑制 NF-κB 减少炎症反应来保护其免受 LPS/GalN 诱导的肝损伤，具有镇痛、抗菌和抗炎的特性。
T3893	Forsythoside B 连翘酯苷 B,连翘脂苷B	TNF; NF-κB	Apoptosis; NF-κB
	Forsythoside B 是传统中药植物独一味叶子中分离的一种苯乙醇苷。它可抑制 TNF-alpha，IL-6，IκB，调节 NF-κB。它抑制炎症反应，具有抗氧化和神经保护作用。
T26545	Acanthoic acid NP1302,NP 1302: NP-1302
	Acanthoic acid is a pimaradiene diterpene isolated from Acanthopanax koreanum with anti-inflammatory activities. Acanthoic acid downregulates LPS-induced IL-1β, IL-6 and TNF-α production in BALF, attenuates lung histopathologic changes, and inhibits infla
TMA2576	Episappanol	IL Receptor; TNF	Apoptosis; Immunology/Inflammation
	Episappanol has anti-inflammatory activity , it can significantly inhibit the secretion of the pro-inflammatory cytokines interleukin (IL-6) and tumor necrosis factor-alpha (TNF-α).
T75674	Pedunculagin	Others	Others
	Pedunculagin为有效的1型5α-还原酶抑制剂，能抑制一氧化氮(NO)、IL-6、IL-8产生，并降低5α-reductase蛋白质表达，具抗炎活性。
T11034	Di-O-methyldemethoxycurcumin	IL Receptor	Immunology/Inflammation
	Di-O-methyldemethoxycurcumin is a Curcumin analog isolated from medicinal plant turmeric di-orthomethyldemethoxycurcumin, anti-inflammatory and antioxidant properties Inhibition of IL-6 production, EC50 is 16.20μg/mL.
TN4190	Hedycoronen A	IL Receptor; TNF	Apoptosis; Immunology/Inflammation
	Hedycoronen A and hedycoronen B have the potential anti-inflammatory benefits, they are potent inhibitors of LPS-stimulated interleukin-6 (IL-6) and IL-12 p40, with IC(50) ranging from 4.1±0.2 to 9.1±0.3 uM, they also show moderate inhibitory activity on
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天然产物

Cat.No: TN6739

Synonym: 6-Methoxyldihydrochelerythrine

Target: IL Receptor, STAT

Terminolic acid

Cat.No: TN6722

Synonym: 2α,6β,23-trihydroxyl oleanolic acid

Target: Antibacterial

Cat.No: T2893

Synonym: 3-Methylcyclopentadecanone,Methylexaltone,麝香酮

Target: MMP, TNF, NF-κB, NOD-like Receptor (NLR), P-gp, Interleukin

Cat.No: TN1520

Synonym: Coleonol B

Target: IL Receptor, TNF

Cat.No: T40660

Target: IL Receptor, SARS-CoV

Cat.No: TN6778

Synonym: 伞形花醚,7-[[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrienyl]oxy]-2H-1-benzopyran-2-oneUmbelliprenin

Target: IL Receptor

fulvotomentoside A

Cat.No: TN6393

Target: Others

Deoxyandrographolide

Cat.No: TQ0218

Synonym: 去氧穿心莲内酯,14-deoxyandrographolide

Target: IL Receptor, TNF

Cat.No: T1048

Synonym: 雌二醇,E2,17β-Estradiol,17β-Oestradiol,β-Estradiol

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Endogenous Metabolite

Cat.No: TN4379

Target: IL Receptor, STAT, Interleukin

Cat.No: TN1154

Synonym: 6-Methoxyluteolin,泽兰黄酮,6-甲氧基藤黄菌素

Target: Calcium Channel, Histamine Receptor

Cat.No: T4S0145

Synonym: Corylinin,补骨脂异黄酮A

Target: hCE, STAT, UGT

Cat.No: T6S1597

Synonym: 桑皮苷 A,桑皮苷A

Target: TNF, Tyrosinase, Interleukin

Cat.No: T2791

Synonym: 柳穿鱼叶苷,大蓟苷

Target: Apoptosis, Others, NO Synthase, Prostaglandin Receptor, Interleukin

Ginsenoside Rh1

Cat.No: T2932

Synonym: Sanchinoside B2,人参皂苷 Rh1,人参皂苷Rh1,Prosapogenin A2,20(S)-Ginsenoside Rh1,Sanchinoside Rh1

Target: IL Receptor, TNF, Endogenous Metabolite, PPAR, Interleukin

Neobavaisoflavone

Cat.No: T6S0139

Target: Apoptosis, DNA/RNA Synthesis

Guanosine 5'-diphosphate

Cat.No: T7210

Synonym: GDP,鸟苷-5ˊ-二磷酸

Target: Endogenous Metabolite

Cat.No: T5S1981

Synonym: (+)-α-Cyperone,α-香附酮,α-Cyperone

Target: Others, Endogenous Metabolite

Liriope muscari baily saponins C

Cat.No: T3809

Target: Others

Cat.No: T3816

Target: NF-κB, HIF/HIF Prolyl-Hydroxylase

Eleutheroside E

Cat.No: T3662

Target: NF-κB

Cat.No: Fr14115

Synonym: Terpineol,α-松油醇

Target: IL Receptor, Anti-infection, Antibacterial

Madecassic acid

Cat.No: T2758

Synonym: 6-Deoxy-L-Galactose,羟基积雪草酸,L-Fucose,Brahmic acid,L-fucopyranose

Target: Others, TNF, COX, NO Synthase, Interleukin

Sodium Thiocyanate

Cat.No: T8033

Target: Others, Reactive Oxygen Species, Interleukin

Asperulosidic acid

Cat.No: TN1410

Synonym: ASPA,车叶草苷酸

Target: ERK, NF-κB

Cat.No: T0798

Synonym: Fluoxyprednisolone,曲安西龙,Aristocort,Rodinolone

Target: Glucocorticoid Receptor, COX

Atractylenolide I

Cat.No: T5S0167

Synonym: 白术内酯 I,白术内酯I；苍术内酯I

Target: IL Receptor, TNF, TLR, JAK, STAT

6-Demethoxytangeretin

Cat.No: T8152

Target: MAPK, ALK

Cat.No: T3926

Synonym: 刺甘草查尔酮,Retrochalcone

Target: Free radical scavengers

Cat.No: TN5171

Target: Apoptosis, Others, Nrf2

4-Methylesculetin

Cat.No: TJS0338

Synonym: 4-Methyl-6,7-dihydroxycoumarin,6,7-二羟基-4-甲基香豆素,Methylesculetin,4-甲基七叶亭

Target: Antioxidant, Glutathione Peroxidase

Cat.No: T6S1315

Synonym: 千层纸素A,6-Methoxybaicalein,Baicalein 6-methyl ether

Target: Virus Protease, HIF/HIF Prolyl-Hydroxylase, Autophagy

Cat.No: T3803

Synonym: 特女贞苷,Nuzhenide,Nuezhenide

Target: Others, NF-κB, Wnt/beta-catenin

Cat.No: T3398

Synonym: Anhydroicaritin,去水淫羊藿黄素,Cycloicaritin

Target: Apoptosis, JAK, STAT, Autophagy

Tetrahydrocoptisine

Cat.No: T4S2063

Synonym: 人血草碱,STYLOPINE

Target: ERK, p38 MAPK, NF-κB

Cat.No: T6S1049

Target: ATPase

Cat.No: T4S1422

Synonym: 白花前胡素 E,白花前胡素E

Target: Others, Calcium Channel

Cat.No: T4115

Synonym: 橙皮油内酯,7-geranyloxycoumarin,橙皮油素

Target: MMP, BACE

Cat.No: T2S0843

Synonym: 黄芩素-7-甲醚,7-O-Methylbaicalein,Baicalein-7-methylether

Target: IL Receptor, TNF, NOS, Interleukin

Ganoderic acid A

Cat.No: T6S1141

Synonym: 灵芝酸 A,灵芝酸A

Target: Apoptosis, NF-κB, Endogenous Metabolite, Autophagy

Cat.No: T3744

Synonym: Veratrumenoic acid,藜芦酸,3,4-Dimethoxybenzoic acid

Target: Reactive Oxygen Species, COX

Cat.No: T6S1917

Synonym: Gomisin A,TJN-101,Besigomsin,五味子醇乙,Gamma-Schisandrin,戈米辛A,Schizandrol B,Wuweizi alcohol-B

Target: P450, Reactive Oxygen Species, Autophagy

Chelidonic acid

Cat.No: T5558

Synonym: Jervaic acid,Jerva acid,白屈菜酸,γ-Pyrone-2,6-dicarboxylic acid

Target: NF-κB, Caspase

Cat.No: T2S2264

Synonym: Linalol,(±)-Linalool,Phantol,沉香醇

Target: Apoptosis, IL Receptor, TNF, Endogenous Metabolite, iGluR

Cat.No: T3893

Synonym: 连翘酯苷 B,连翘脂苷B

Target: TNF, NF-κB

Cat.No: T26545

Synonym: NP1302,NP 1302: NP-1302

Cat.No: TMA2576

Target: IL Receptor, TNF

Cat.No: T75674

Target: Others

Di-O-methyldemethoxycurcumin

Cat.No: T11034

Target: IL Receptor

Cat.No: TN4190

Target: IL Receptor, TNF

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Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-03238	IL-6 Protein, Mouse, Recombinant 白介素,Il-6,白细胞介素,interleukin 6	Mouse	E. coli
	IL-6 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 21.9 kDa and the accession number is P08505.
TMPY-00863	IL-6 Protein, Human, Recombinant BSF2,白细胞介素,HSF,IL-6,IFNB2,interleukin ...	Human	E. coli
	IL-6 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 20.95 kDa and the accession number is P05231.
TMPY-00864	IL-6R Protein, Human, Recombinant (His) IL-6R-1,IL-6RA,IL	Human	HEK293 Cells
	IL-6R Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is A0N0L5.
TMPY-05278	IL-6R Protein, Human, Recombinant (hFc) IL-6R-1,CD126,gp80,IL	Human	HEK293 Cells
	IL-6R Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.3 kDa and the accession number is A0N0L5.
TMPY-01214	IL-6R Protein, Mouse, Recombinant (His) MGC30256,IL-6R,Il6	Mouse	HEK293 Cells
	IL-6R Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39 kDa and the accession number is P22272.
TMPY-01076	gp130/IL6ST Protein, Human, Recombinant (His & hFc) interleukin 6 signal transducer,IL-6	Human	HEK293 Cells
	gp130/IL6ST Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 96 kDa and the accession number is P40189-1.
TMPY-03802	IL-17F Protein, Human, Recombinant (aa 31-163) ML1,ML-1,IL-17F,interleukin 17F,CANDF6	Human	E. coli
	IL-17F Protein, Human, Recombinant (aa 31-163) is expressed in E. coli expression system. The predicted molecular weight is 15.1 kDa and the accession number is AAH70124.1.
TMPY-03298	IL-6 Protein, Rat, Recombinant 白细胞介素,interleukin 6,白介素	Rat	E. coli
	IL-6 Protein, Rat, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 21.9 kDa and the accession number is A6KJN3.
TMPY-03327	IL-6 Protein, Rhesus, Recombinant 白介素,interleukin 6,白细胞介素	Rhesus	E. coli
	IL-6 Protein, Rhesus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 21 kDa and the accession number is A0A1D5QRZ4.
TMPK-00101	IL-6 Protein, Cynomolgus, Recombinant (His) CDF,BSF-2,白介素,IL6,HGF,白细胞介素,Interleukin-	Cynomolgus	HEK293 Cells
	IL-6 (Interleukin-6) is a pleiotropic cytokine that acts in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression.Interleukin 6 has been shown to interact with interleukin-6 receptor and glycoprotein.
TMPY-02879	IL-36 alpha/IL-1F6 Protein, Human, Recombinant (aa 6-158) interleukin 36, alpha,白细胞介素,FIL1(ε),IL...	Human	E. coli
	IL-36 alpha/IL-1F6 Protein, Human, Recombinant (aa 6-158) is expressed in E. coli expression system. The predicted molecular weight is 17.2 kDa and the accession number is Q9UHA7.
TMPY-02603	STAT6 Protein, Human, Recombinant (His) STAT6C,IL-4-STAT,STAT6B,signal tr...	Human	Baculovirus Insect Cells
	Signal transducer and activator of transcription 6 (STAT6) is a transcription factor that is activated by interleukin-4 (IL-4)-induced tyrosine phosphorylation and mediates most of the IL-4-induced gene expression. STAT6 plays a central role in exerting interleukin-4 (IL-4) mediated biological responses and is found to induce the expression of BCL2L1/BCL-XL, which is responsible for the anti-apoptotic activity of IL4. Transcriptional activation by STAT6 requires the interaction with coactivators...
TMPK-00412	gp130/IL6ST Protein, Human, Recombinant (His) gp130,CD130,IL-6 R beta,IL6	Human	HEK293 Cells
	gp130 is a common signal transducing component of the functional receptor complexes for the interleukin (IL)-6 family of cytokines, ie, IL-6, IL-11, leukemia inhibitory factor (LIF), oncostatin M, ciliary neurotrophic factor, and cardiotrophin-1. These cytokines exhibit pleiotropic biological activities in, for instance, immune, hematopoietic, and neural systems, and function in a redundant manner owing to the shared usage of gp130. gp130/IL6ST Protein, Human, Recombinant (His) is expressed in H...
TMPK-00646	gp130/IL6ST Protein, Rhesus macaque, Recombinant (His) IL-6 R β,gp130,IL6ST,	Rhesus	HEK293 Cells
	gp130 is a common signal transducing component of the functional receptor complexes for the interleukin (IL)-6 family of cytokines, ie, IL-6, IL-11, leukemia inhibitory factor (LIF), oncostatin M, ciliary neurotrophic factor, and cardiotrophin-1. These cytokines exhibit pleiotropic biological activities in, for instance, immune, hematopoietic, and neural systems, and function in a redundant manner owing to the shared usage of gp130. gp130/IL6ST Protein, Rhesus macaque, Recombinant (His) is expre...
TMPY-05640	IL-6R Protein, Human, Recombinant, Biotinylated IL6RQ,IL-6R,IL<...	Human	HEK293 Cells
	IL-6R Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 67.1 kDa and the accession number is A0N0L5.
TMPY-06297	IL-6R Protein, Human, Recombinant (His & Avi), Biotinylated CD126,IL-6RA,IL6	Human	HEK293 Cells
	IL-6R Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 41.80 kDa and the accession number is A0N0L5.
TMPJ-00291	IL-6R alpha/CD126 Protein, Human, Recombinant (Avi & His), Biotinylated IL-6R-α,IL-6R-alpha,Inte...	Human	HEK293 Cells
	Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. IL6Ra is a part of the receptor for interleukin 6 cytokine. IL6Ra binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitates an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis. Low concentration of a soluble form of IL6 receptor acts as an...
TMPY-00387	gp130/IL6ST Protein, Human, Recombinant (hFc) GP130,CD130,interleukin 6 signal transducer,IL<...	Human	HEK293 Cells
	gp130/IL6ST Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 94.4 kDa and the accession number is AAA59155.1.
TMPY-06745	gp130/IL6ST Protein, Human, Recombinant (mFc) interleukin 6 signal transducer,CD130,CDW130,IL...	Human	HEK293 Cells
	gp130/IL6ST Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 94.11 kDa and the accession number is AAA59155.1.
TMPK-00289	IL-6R alpha/CD126 Protein, Human, Recombinant (His & Avi) IL-6R subunit alpha,IL-6...	Human	HEK293 Cells
	The multifunctional factor interleukin 6 (IL-6) exerts its activities through binding to a high-affinity receptor complex consisting of two membrane glycoproteins: an 80 kDa component receptor that binds IL-6 with low affinity (IL-6R alpha) and a signal-transducing component of 130 kDa (gp130) that does not bind IL-6 by itself, but is required for high-affinity binding of IL-6 by the complex. Both components of the receptor complex, IL-6R alpha and gp130 have been cloned, sequenced, and expresse...
TMPY-06039	gp130/IL6ST Protein, Human, Recombinant (aa 1-618, DDDDK) GP130,CD130,interleukin 6 signal transducer,CDW130,...	Human	HEK293 Cells
	gp130/IL6ST Protein, Human, Recombinant (aa 1-618, DDDDK) is expressed in HEK293 mammalian cells. The predicted molecular weight is 68.4 kDa and the accession number is P40189-1.
TMPY-01832	gp130/IL6ST Protein, Mouse, Recombinant (His) CD130,D13Ertd699e,interleukin 6 signal tra...	Mouse	HEK293 Cells
	gp130/IL6ST Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 68 kDa and the accession number is Q00560.
TMPK-00046	IL-17F Protein, Human, Recombinant (His & Avi), Biotinylated CANDF6,IL-24,IL24,IL17F,...	Human	HEK293 Cells
	IL-17F Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17.5 /14.9 kDa and the accession number is Q96PD4.
TMPK-00041	IL-17F Protein, Mouse, Recombinant (His & Avi) IL-24,IL17F,ML1,IL-17F,Cytokine M...	Mouse	HEK293 Cells
	IL-17F Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17.8 kDa and the accession number is Q7TNI7-1.
TMPK-00042	IL-17F Protein, Mouse, Recombinant (His & Avi), Biotinylated CANDF6,ML1,Cytokine ML-1,IL17F,IL...	Mouse	HEK293 Cells
	IL-17F Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17.8 kDa and the accession number is Q7TNI7-1.
TMPY-01898	IL-17F Protein, Human, Recombinant (aa 31-163, His) CANDF6,IL-17F,interleukin 17F,ML-1,ML1	Human	HEK293 Cells
	IL-17F Protein, Human, Recombinant (aa 31-163, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.2 kDa and the accession number is Q96PD4.
TMPJ-00194	IL-20RB Protein, Human, Recombinant (hFc) DIRS1,IL-20R-β,Interleukin-20 receptor subunit β,	Human	HEK293 Cells
	Interleukin-20 receptor subunit beta（IL20RB） is a single-pass type I membrane protein and belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains. There are two kinds of type II cytokine receptors : cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleukin-10 family (interleukin-10, interleukin-20 and interleukin-22). Type II cytokine receptors are similar to type I cytokine receptors except they do no...
TMPY-05461	IL-17F Protein, Human, Recombinant (His), Biotinylated ML-1,CANDF6,interleukin 17F,IL-17F,ML1	Human	HEK293 Cells
	IL-17F Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 73.3 kDa and the accession number is Q96PD4.
TMPY-05559	IL-20RB Protein, Human, Recombinant (His) interleukin 20 receptor β,interleukin 20 receptor beta,I...	Human	Baculovirus Insect Cells
	IL-20RB Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 23.9 kDa and the accession number is Q6UXL0-1.
TMPH-03208	IL-6 Protein, Rabbit, Recombinant (His) Interleukin-6,IL6	Rabbit	P. pastoris (Yeast)
	IL-6 Protein, Rabbit, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 26.4 kDa and the accession number is Q9MZR1.
TMPH-03500	IL-6 Protein, Sheep, Recombinant (GST) IL6,Interleukin-6	Sheep	E. coli
	IL-6 Protein, Sheep, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 47.5 kDa and the accession number is P29455.
TMPY-04183	IL-6 Protein, Sus scrofa (Pig), Recombinant 白细胞介素,白介素,interleukin 6	Sus scrofa (Pig)	E. coli
	IL-6 Protein, Sus scrofa (Pig), Recombinant is expressed in E. coli expression system. The predicted molecular weight is 21.2 kDa and the accession number is A4D862.
TMPY-01956	IL-36 alpha/IL-1F6 Protein, Mouse, Recombinant IL1(ε),FIL1(ε),IL36 α/	Mouse	E. coli
	IL-36 alpha/IL-1F6 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18 kDa and the accession number is Q9JLA2-1.
TMPY-02818	IL-36 alpha/IL-1F6 Protein, Human, Recombinant (His) 白细胞介素,FIL1,白介素,interleukin 36, α,IL	Human	E. coli
	IL-36 alpha/IL-1F6 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 19.2 kDa and the accession number is Q9UHA7.
TMPY-04187	IL-6R Protein, Rat, Recombinant (hFc) interleukin 6 receptor	Rat	HEK293 Cells
	IL-6R Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 64.8 kDa and the accession number is A6J6I0.
TMPY-00135	IL-6R Protein, Canine, Recombinant (His) interleukin 6 receptor	Canine	HEK293 Cells
	IL-6R Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.8 kDa and the accession number is A0A8C0PF44.
TMPY-02560	IL-6R Protein, Rat, Recombinant (His) interleukin 6 receptor	Rat	HEK293 Cells
	IL-6R Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.5 kDa and the accession number is A6J6I0.
TMPY-04859	IL-6R Protein, Rhesus, Recombinant (His) interleukin 6 receptor	Rhesus	HEK293 Cells
	IL-6R Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.6 kDa and the accession number is A0A5F8AUE5.
TMPK-00638	IL-1 Rrp2/IL-1 R6 Protein, Cynomolgus, Recombinant (His) IL1RL2,IL-1 Rrp2,IL-36R,...	Cynomolgus	HEK293 Cells
	IL-1 Rrp2/IL-1 R6 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 37.1 kDa and the accession number is G8F338.
TMPK-00332	IL-1 Rrp2/IL-1 R6 Protein, Human, Recombinant (His & Avi) IL1RL2,IL-1 R6,IL-1 Rrp2...	Human	HEK293 Cells
	IL-1 Rrp2/IL-1 R6 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 39.1 kDa and the accession number is Q9HB29-1.
TMPK-00333	IL-1 Rrp2/IL-1 R6 Protein, Human, Recombinant (His & Avi), Biotinylated IL-1 Rrp2,IL-1 R6,IL1RL2...	Human	HEK293 Cells
	IL-1 Rrp2/IL-1 R6 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 39.1 kDa and the accession number is Q9HB29-1.
TMPY-03743	gp130/IL6ST Protein, Rhesus, Recombinant (His) interleukin 6 signal transducer	Rhesus	HEK293 Cells
	gp130/IL6ST Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.2 kDa and the accession number is A0A8J8YAN3.
TMPY-02148	gp130/IL6ST Protein, Rat, Recombinant (His) interleukin 6 signal transducer	Rat	HEK293 Cells
	gp130/IL6ST Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 68.2 kDa and the accession number is H9BFG4.
TMPY-05793	gp130/IL6ST Protein, Mouse, Recombinant (hFc) BB405851,interleukin 6 signal transducer,D13Ertd	Mouse	HEK293 Cells
	gp130/IL6ST Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 93.38 kDa and the accession number is Q00560.
TMPY-03687	gp130/IL6ST Protein, Rhesus, Recombinant (hFc) interleukin 6 signal transducer	Rhesus	HEK293 Cells
	gp130/IL6ST Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 102.6 kDa and the accession number is A0A8J8YAN3.
TMPY-01995	gp130/IL6ST Protein, Rat, Recombinant (His & mFc) interleukin 6 signal transducer	Rat	HEK293 Cells
	gp130/IL6ST Protein, Rat, Recombinant (His & mFc) is expressed in HEK293 mammalian cells with His, mFc tag. The predicted molecular weight is 94.3 kDa and the accession number is H9BFG4.
TMPJ-01172	IL-17 Protein, Mouse, Recombinant (His) CTLA8,IL-17,IL-17A,Interleukin-17A,CTLA-8,...	Mouse	HEK293 Cells
	Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Mature mouse IL-17A shares 61% and 89% amino acid sequence identity with human and rat IL-17A, respectively. As IL-17 shares properties with IL-1 and TNF-alpha, it may induce joint inflammation and bone and cartilage destruction. This cytokine is found in synovial fluids of patients with rheumatoid arthritis, and produced by rheumato...
TMPY-06981	IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli) interleukin 1 α,IL1,白介素,IL-1F1,IL...	Human	E. coli
	IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation, and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophage...
TMPJ-01467	Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His) Oncostatin-M,OSM	Human	E. coli
	Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. OSM encodes a growth regulator, which Inhibits the proliferation of a number of tumor cell lines. It stimulates proliferation of AIDS-KS cells. OSM regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. OSM is considered as a pleiotropic cytokine that initiates its biological ac...
TMPH-01578	KRT18 Protein, Human, Recombinant (His) Keratin, type I cytoskeletal 18,KRT18,Cell proliferation-ind...	Human	HEK293 Cells
	Involved in the uptake of thrombin-antithrombin complexes by hepatic cells. When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
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重组蛋白

IL-6 Protein, Mouse, Recombinant

Cat.No: TMPY-03238

Species: Mouse

Expression System: E. coli

IL-6 Protein, Human, Recombinant

Cat.No: TMPY-00863

Species: Human

Expression System: E. coli

IL-6R Protein, Human, Recombinant (His)

Cat.No: TMPY-00864

Species: Human

Expression System: HEK293 Cells

IL-6R Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05278

Species: Human

Expression System: HEK293 Cells

IL-6R Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01214

Species: Mouse

Expression System: HEK293 Cells

gp130/IL6ST Protein, Human, Recombinant (His & hFc)

Cat.No: TMPY-01076

Species: Human

Expression System: HEK293 Cells

IL-17F Protein, Human, Recombinant (aa 31-163)

Cat.No: TMPY-03802

Species: Human

Expression System: E. coli

IL-6 Protein, Rat, Recombinant

Cat.No: TMPY-03298

Species: Rat

Expression System: E. coli

IL-6 Protein, Rhesus, Recombinant

Cat.No: TMPY-03327

Species: Rhesus

Expression System: E. coli

IL-6 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00101

Species: Cynomolgus

Expression System: HEK293 Cells

IL-36 alpha/IL-1F6 Protein, Human, Recombinant (aa 6-158)

Cat.No: TMPY-02879

Species: Human

Expression System: E. coli

STAT6 Protein, Human, Recombinant (His)

Cat.No: TMPY-02603

Species: Human

Expression System: Baculovirus Insect Cells

gp130/IL6ST Protein, Human, Recombinant (His)

Cat.No: TMPK-00412

Species: Human

Expression System: HEK293 Cells

gp130/IL6ST Protein, Rhesus macaque, Recombinant (His)

Cat.No: TMPK-00646

Species: Rhesus

Expression System: HEK293 Cells

IL-6R Protein, Human, Recombinant, Biotinylated

Cat.No: TMPY-05640

Species: Human

Expression System: HEK293 Cells

IL-6R Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-06297

Species: Human

Expression System: HEK293 Cells

IL-6R alpha/CD126 Protein, Human, Recombinant (Avi & His), Biotinylated

Cat.No: TMPJ-00291

Species: Human

Expression System: HEK293 Cells

gp130/IL6ST Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00387

Species: Human

Expression System: HEK293 Cells

gp130/IL6ST Protein, Human, Recombinant (mFc)

Cat.No: TMPY-06745

Species: Human

Expression System: HEK293 Cells

IL-6R alpha/CD126 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00289

Species: Human

Expression System: HEK293 Cells

gp130/IL6ST Protein, Human, Recombinant (aa 1-618, DDDDK)

Cat.No: TMPY-06039

Species: Human

Expression System: HEK293 Cells

gp130/IL6ST Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01832

Species: Mouse

Expression System: HEK293 Cells

IL-17F Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00046

Species: Human

Expression System: HEK293 Cells

IL-17F Protein, Mouse, Recombinant (His & Avi)

Cat.No: TMPK-00041

Species: Mouse

Expression System: HEK293 Cells

IL-17F Protein, Mouse, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00042

Species: Mouse

Expression System: HEK293 Cells

IL-17F Protein, Human, Recombinant (aa 31-163, His)

Cat.No: TMPY-01898

Species: Human

Expression System: HEK293 Cells

IL-20RB Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00194

Species: Human

Expression System: HEK293 Cells

IL-17F Protein, Human, Recombinant (His), Biotinylated

Cat.No: TMPY-05461

Species: Human

Expression System: HEK293 Cells

IL-20RB Protein, Human, Recombinant (His)

Cat.No: TMPY-05559

Species: Human

Expression System: Baculovirus Insect Cells

IL-6 Protein, Rabbit, Recombinant (His)

Cat.No: TMPH-03208

Species: Rabbit

Expression System: P. pastoris (Yeast)

IL-6 Protein, Sheep, Recombinant (GST)

Cat.No: TMPH-03500

Species: Sheep

Expression System: E. coli

IL-6 Protein, Sus scrofa (Pig), Recombinant

Cat.No: TMPY-04183

Species: Sus scrofa (Pig)

Expression System: E. coli

IL-36 alpha/IL-1F6 Protein, Mouse, Recombinant

Cat.No: TMPY-01956

Species: Mouse

Expression System: E. coli

IL-36 alpha/IL-1F6 Protein, Human, Recombinant (His)

Cat.No: TMPY-02818

Species: Human

Expression System: E. coli

IL-6R Protein, Rat, Recombinant (hFc)

Cat.No: TMPY-04187

Species: Rat

Expression System: HEK293 Cells

IL-6R Protein, Canine, Recombinant (His)

Cat.No: TMPY-00135

Species: Canine

Expression System: HEK293 Cells

IL-6R Protein, Rat, Recombinant (His)

Cat.No: TMPY-02560

Species: Rat

Expression System: HEK293 Cells

IL-6R Protein, Rhesus, Recombinant (His)

Cat.No: TMPY-04859

Species: Rhesus

Expression System: HEK293 Cells

IL-1 Rrp2/IL-1 R6 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00638

Species: Cynomolgus

Expression System: HEK293 Cells

IL-1 Rrp2/IL-1 R6 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00332

Species: Human

Expression System: HEK293 Cells

IL-1 Rrp2/IL-1 R6 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00333

Species: Human

Expression System: HEK293 Cells

gp130/IL6ST Protein, Rhesus, Recombinant (His)

Cat.No: TMPY-03743

Species: Rhesus

Expression System: HEK293 Cells

gp130/IL6ST Protein, Rat, Recombinant (His)

Cat.No: TMPY-02148

Species: Rat

Expression System: HEK293 Cells

gp130/IL6ST Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-05793

Species: Mouse

Expression System: HEK293 Cells

gp130/IL6ST Protein, Rhesus, Recombinant (hFc)

Cat.No: TMPY-03687

Species: Rhesus

Expression System: HEK293 Cells

gp130/IL6ST Protein, Rat, Recombinant (His & mFc)

Cat.No: TMPY-01995

Species: Rat

Expression System: HEK293 Cells

IL-17 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-01172

Species: Mouse

Expression System: HEK293 Cells

IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli)

Cat.No: TMPY-06981

Species: Human

Expression System: E. coli

Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His)

Cat.No: TMPJ-01467

Species: Human

Expression System: E. coli

KRT18 Protein, Human, Recombinant (His)

Cat.No: TMPH-01578

Species: Human

Expression System: HEK293 Cells

--------- 更多 ---------

Cat. No.	Product Name	Target	Signaling Pathways
T36408	Rhein-13C4 Rhein-13C4
	Rhein-13C4 is intended for use as an internal standard for the quantification of rhein by GC- or LC-MS. Rhein is an anti-inflammatory anthraquinone found in rhubarb and is the bioactive derivative of its prodrug diacerein . At 10 μM, rhein inhibits IL-1β signaling, suppressing signaling through NF-κB, and reduces the expression of the matrix metalloproteases MMP-1 and MMP-13.1 It inhibits IKKβ (IC50 = 11.8 μM), decreasing iNOS and IL-6 expression in LPS-stimulated macrophages but paradoxically i...
T71285	Metaxalone-d6
	Metaxalone-d6 is intended for use as an internal standard for the quantification of metaxalone by GC-or LC-MS. Metaxalone is a skeletal muscle relaxant. It inhibits the proliferation of, and induces apoptosis in, RAW 264.7 cells in vitro when used at concentrations ranging from 1 to 100 µM. Metaxalone also reduces LPS-induced increases in COX-1, COX-2, and NF-kB levels and inhibits LPS-induced production of TNF-α, IL-6, and prostaglandin E2 in RAW 264.7 cells. Formulations containing metaxalone ...
T71212	Lornoxicam-d4
	Lornoxicam-d4 is intended for use as an internal standard for the quantification of lornoxicam by GC- or LC-MS. Lornoxicam is a COX inhibitor and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory and analgesic properties. It inhibits production of thromboxane B2 from arachidonic acid in HEL human erythroleukemic cells, which endogenously express COX-1, as well as inhibits LPS-induced formation of prostaglandin F1α from arachidonic acid in Mono-Mac-6 cells, which endogenously e...
TMID-0254	Linalool-d3
	Linalool-d3 是 Linalool 的氘代化合物。Linalool 的 CAS 号为 78-70-6。Linalool 是存在芫荽等植物中的单萜类天然产物，是竞争性NMDA受体拮抗剂，具有抗肿瘤和抗心脏毒性的作用。它通过激活 Nrf2 诱导抗氧化防御和通过抑制 NF-κB 减少炎症反应来保护其免受 LPS/GalN 诱导的肝损伤，具有镇痛、抗菌和抗炎的特性。
T71328	Theobromine-d6
	Theobromine-d6 is intended for use as an internal standard for the quantification of theobromine by GC- or LC-MS. Theobromine is a methylxanthine alkaloid and derivative of caffeine that has been found in cocoa beans and has diverse biological activities. It is an adenosine A1 receptor antagonist. Theobromine increases AMPK phosphorylation and inhibits adipocyte differentiation, ERK and JNK phosphorylation, and IL-6 and TNF-α production in 3T3-L1 preadipocytes cultured in differentiation medium....
TMID-0146	Methylprednisolone-d7
	Methylprednisolone-d7 是 Methylprednisolone 的氘代化合物。Methylprednisolone 的 CAS 号为 83-43-2。Methylprednisolone 是一种具有类似抗炎作用的强的松龙衍生物。它是皮质类固醇，可作用于糖皮质激素受体。它通过激活ACE2并降低 IL-6 水平来改善严重的COVID-19。
TMID-0145	Methylprednisolone-d2
	Methylprednisolone-d2 是 Methylprednisolone 的氘代化合物。Methylprednisolone 的 CAS 号为 83-43-2。Methylprednisolone 是一种具有类似抗炎作用的强的松龙衍生物。它是皮质类固醇，可作用于糖皮质激素受体。它通过激活ACE2并降低 IL-6 水平来改善严重的COVID-19。
TMIJ-0196	17β-Estradiol-16,16,17-d3
	17β-Estradiol-16,16,17-d3 是 17β-Estradiol 的氘代化合物。17β-Estradiol 的 CAS 号为 50-28-2。Estradiol 是一种类固醇性激素，对于女性生育能力和第二性征的维持至关重要。它通过雌激素受体 β 途径上调 IL-6 表达。
TMIJ-0028	17β-Estradiol-2,4-d2
	17β-Estradiol-2,4-d2 是 17β-Estradiol 的氘代化合物。17β-Estradiol 的 CAS 号为 50-28-2。Estradiol 是一种类固醇性激素，对于女性生育能力和第二性征的维持至关重要。它通过雌激素受体 β 途径上调 IL-6 表达。
TMID-0055	17β-estradiol-d4
	17β-estradiol-d4 是 17β-estradiol 的氘代化合物。17β-estradiol 的 CAS 号为 50-28-2。Estradiol 是一种类固醇性激素，对于女性生育能力和第二性征的维持至关重要。它通过雌激素受体 β 途径上调 IL-6 表达。
TMIJ-0032	17beta-Estradiol-13C2
	17beta-Estradiol-13C2 是 17beta-Estradiol 的 13C 的标记化合物。17beta-Estradiol 的 CAS 号为 50-28-2。Estradiol 是一种类固醇性激素，对于女性生育能力和第二性征的维持至关重要。它通过雌激素受体 β 途径上调 IL-6 表达。
TMID-0108	17β-Estradiol-2,4,16,16,17-d5
	17β-Estradiol-2,4,16,16,17-d5 是 17β-Estradiol 的氘代化合物。17β-Estradiol 的 CAS 号为 50-28-2。Estradiol 是一种类固醇性激素，对于女性生育能力和第二性征的维持至关重要。它通过雌激素受体 β 途径上调 IL-6 表达。

同位素标记化合物

Cat.No: T36408

Synonym: Rhein-13C4

Cat.No: T71285

Cat.No: T71212

Cat.No: TMID-0254

Cat.No: T71328

Methylprednisolone-d7

Cat.No: TMID-0146

Methylprednisolone-d2

Cat.No: TMID-0145

17β-Estradiol-16,16,17-d3

Cat.No: TMIJ-0196

17β-Estradiol-2,4-d2

Cat.No: TMIJ-0028

17β-estradiol-d4

Cat.No: TMID-0055

17beta-Estradiol-13C2

Cat.No: TMIJ-0032

17β-Estradiol-2,4,16,16,17-d5

Cat.No: TMID-0108

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