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Search Results for " iecs "
Targets Recommended: Sodium Channel TRP/TRPV Channel

2

抑制剂 & 化合物

2

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
TQ0157 EIPA

L593754,MH 12-43

Sodium Channel; TRP/TRPV Channel Membrane transporter/Ion channel
EIPA (L593754) 是一种有效的TRPP3 channel 抑制剂,IC50为 10.5 μM。EIPA 对Na+/H+交换 (NHE) 和巨噬细胞也有抑制作用。
T11172 EIPA hydrochloride

L593754 hydrochloride,MH 12-43 hydrochloride

TRP/TRPV Channel Membrane transporter/Ion channel
EIPA hydrochloride also inhibits Na+/H+-exchanger (NHE) and macropinocytosisEIPA hydrochloride (L593754 hydrochloride) is a TRPP3 channel inhibitor with an IC50 of 10.5 μM.

化合物

EIPA
Cat.No: TQ0157
Synonym: L593754,MH 12-43
Target: Sodium Channel, TRP/TRPV Channel
EIPA hydrochloride
Cat.No: T11172
Synonym: L593754 hydrochloride,MH 12-43 hydrochloride
Target: TRP/TRPV Channel
Cat. No. Product Name Species Expression System
TMPY-03673 REG3B Protein, Mouse, Recombinant (His)

Pap,HIP,REG-III,PAP1

Mouse HEK293 Cells
Expression of REG3B was sufficient to inhibit cytokine-induced activation of STAT3 in IECs. The human REG3beta protein, the functional counterpart of mouse REG3B, inhibited STAT3 activity in human 293T cells, and its expression level in colorectal tumors correlated inversely with pSTAT3 level and survival times of patients. REG3B negatively regulates cytokine-induced activation of STAT3 in colon epithelial cells. This pathway might be targeted in patients with colitis to reduce carcinogenesis.
TMPJ-00200 EpCAM/TROP1 Protein, Mouse, Recombinant (hFc)

17-1A,323/A3,TROP1,EGP314,ACSTD1,CD326,EGP-2,MOC31,EGP40,TAC...

Mouse HEK293 Cells
Epithelial Cellular Adhesion Molecule (Ep-CAM), also known as EGP314, mEGP314, Protein 289A, Tumor-associated calcium signal transducer 1, CD326, belongs to the EPCAM family. Its’ monomer subunit structure interacts with phosphorylated CLDN7. Ep-CAM may act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection...

重组蛋白

REG3B Protein, Mouse, Recombinant (His)
Cat.No: TMPY-03673
Species: Mouse
Expression System: HEK293 Cells
EpCAM/TROP1 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00200
Species: Mouse
Expression System: HEK293 Cells
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