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46
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T11615 |
IDO-IN-12
|
IDO; Indoleamine 2,3-Dioxygenase (IDO) | Metabolism |
IDO-IN-12 是吲哚胺 2,3-双加氧酶抑制剂。 | |||
T11616 |
IDO-IN-13
GS-4361 |
IDO; Indoleamine 2,3-Dioxygenase (IDO) | Metabolism |
IDO-IN-13 (GS-4361) 是 indoleamine 2,3-dioxygenase 1 抑制剂,EC50=17 nM。 | |||
T7181 |
IDO-IN-1
4-氨基-N-(3-溴-4-氟苯基)-N'-羟基-1,2,5-恶二唑-3-甲脒 |
Indoleamine 2,3-Dioxygenase (IDO) | Metabolism |
IDO-IN-1 是吲哚胺-2,3-双加氧酶抑制剂,IC50=59 nM。 | |||
T7660 |
IDO inhibitor 1
4-[[2-[(氨基磺酰基)氨基]乙基]氨基]-N'-(3-溴-4-氟苯基)-N-羟基-1,2,5-恶二唑-3-甲脒 |
Indoleamine 2,3-Dioxygenase (IDO) | Metabolism |
IDO inhibitor 1 是一种有效的吲哚胺-2,3 双加氧酶 (IDO) 抑制剂 (IC50 <100 nM)。具有潜在的免疫调节和抗肿瘤活性。 | |||
T1806 |
IDO-IN-7
NLG919,Navoximod,NLG-919 analogue,GDC-0919 |
Indoleamine 2,3-Dioxygenase (IDO) | Metabolism |
IDO-IN-7 (NLG-919 analogue) 是 IDO1 抑制剂,IC50=38 nM。 | |||
T4142 |
PCC0208009
IDO inhibitor 1,DO-IN-2,IDO-IN-2 |
Indoleamine 2,3-Dioxygenase (IDO) | Metabolism |
PCC0208009 (IDO-IN-2) 是一种有效的 IDO 抑制剂,其在 HeLa 细胞中的 IC50=4.52 nM。它调节 ACC 和杏仁核的突触可塑性,减少神经性疼痛和合并症。 | |||
T3548 |
Epacadostat
INCB 024360,艾卡哚司他,IDO Inhibitor 1 |
IDO; Indoleamine 2,3-Dioxygenase (IDO) | Metabolism |
Epacadostat (INCB 024360) 是选择性的IDO1抑制剂,IC50=71.8 nM。 | |||
T11901 |
IDO1-IN-5
|
IDO; Indoleamine 2,3-Dioxygenase (IDO) | Metabolism |
IDO1-IN-5 是可透过血脑屏障的、选择性的IDO1抑制剂,能够与缺乏血红素的 apo-IDO1 结合,但无法与成熟血红素的 IDO1 结合。 | |||
T40093 |
IDO-IN-15
|
Others | Others |
IDO-IN-15 is an IDO1 inhibitor ( IC 50 < 0.51 nM). | |||
T11618 |
IDO-IN-4
|
Others | Others |
IDO-IN-4 is an indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor. | |||
T11614 | IDO-IN-11 | IDO | Metabolism |
IDO-IN-11 is an indoleamine-2,3-dioxygenase (IDO) inhibitor with IC50s of 0.18 μM (Kinase) and 0.014 μM (Hela Cell). | |||
T11619 |
IDO-IN-5
NLG-1489 |
IDO | Metabolism |
IDO-IN-5 is an indoleamine 2,3-dioxygenase (IDO) inhibitor (IC50: 1-10 μM). | |||
T11617 | IDO-IN-3 | IDO | Metabolism |
IDO-IN-3 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor (IC50: 290 nM). | |||
T11622 |
IDO-IN-9
|
IDO | Metabolism |
IDO-IN-9 is an indoleamine-2,3-dioxygenase (IDO) inhibitor with IC50s of 0.011 μM (Kinase) and 0.0018 μM (Hela Cell). | |||
T11623 |
IDO/TDO-IN-1
|
Others | Others |
IDO/TDO-IN-1 is an orally active dual indoleamine-2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) inhibitor (IC50s: 9.7 and 47 nM). | |||
T11620 |
IDO-IN-6
NLG-1486 |
IDO | Metabolism |
IDO-IN-6 is an indoleamine 2,3-dioxygenase (IDO) inhibitor. | |||
T11621 |
IDO-IN-8
NLG-1487 |
IDO | Metabolism |
IDO-IN-8 is an indoleamine 2,3-dioxygenase (IDO) inhibitor (IC50: 1-10 μM). | |||
T11626 |
IACS-8968
IDO/TDO Inhibitor |
IDO | Metabolism |
IACS-8968 is a dual IDO and TDO inhibitor (pIC50s: 6.43 for IDO and <5 for TDO). | |||
T62130 |
IDO-IN-16
|
Others | Others |
IDO-IN-16 (compound 5) 是一种 IDO 抑制剂 (IC50: 36 nM)。 | |||
T11627 |
IACS-8968 R-enantiomer
IDO/TDO Inhibitor (R-enantiomer) |
IDO | Metabolism |
IACS-8968 R-enantiomer is the R-enantiomer of IACS-8968. IACS-8968 is a dual IDO and TDO inhibitor (pIC50s: 6.43 for IDO and <5 for TDO). | |||
T62270 |
IDO-IN-14
|
Others | Others |
IDO-IN-14 是一种 IDO 抑制剂 (IC50: 0.6928 nM)。 | |||
T11628 |
IACS-8968 S-enantiomer
IDO/TDO Inhibitor (S-enantiomer) |
IDO | Metabolism |
IACS-8968 S-enantiomer is the S-enantiomer of IACS-8968. IACS-8968 is a dual IDO and TDO inhibitor (pIC50s: 6.43 for IDO and <5 for TDO). | |||
T2647 |
IDO5L
INCB024360 analogue,INCB14943 |
IDO; Indoleamine 2,3-Dioxygenase (IDO) | Metabolism |
IDO5L (INCB024360 analogue) 是一种有效的吲哚胺-2,3-双加氧酶 (IDO) 抑制剂,IC50=67 nM。 | |||
T74536 |
IDO/Tubulin-IN-2
|
Others | Others |
IDO/Tubulin-IN-2 (HT2) 是一种对TDO和微管蛋白 (tubulin)展现出高效抑制作用的化合物。该抑制剂对多种癌细胞系(包括U87、HepG2、A549、HCT-116和LO2)均表现出强抗肿瘤活性,其半抑制浓度(IC50)分别为0.43、0.036、0.041、0.095和1.04 μM,有效提升了抗肿瘤效果。 | |||
T39839 |
IDO1-IN-11
IDO1-IN-11 |
Others | Others |
IDO1-IN-11 is an IDO1 inhibitor with an IC 50 value of 0.6 nM. | |||
T39888 |
IDO1-IN-7
IDO1-IN-7 |
Others | Others |
IDO1-IN-7, a potent and selective indoleamine-2,3-dioxygenase-1 (IDO1) inhibitor, exhibits high potency with an IC 50 of 6.1 nM in the cellular assay (SKOV3). Apart from its inhibitory properties, IDO1-IN-7 also demonstrates immunomodulatory effects, contributing to its potential applications in cancer research. | |||
T84728 |
(R)-IDO/TDO-IN-1
|
Others | Others |
(R)-IDO/TDO-IN-1 (化合物 25) 为一种具有优良药动学性质的吲哚胺-2,3-双加氧酶 (IDO) 抑制剂,在MC38异种移植模型中展现出抗肿瘤活性。该化合物还与抗PD-1单克隆抗体 (SHR-1210) 显示协同作用。 | |||
T39946 |
IDO1-IN-12
IDO1-IN-12 |
Others | Others |
IDO1-IN-12 is a potent and orally available IDO1 inhibitor. | |||
T37329 |
PROTAC IDO1 Degrader-1
PROTAC IDO1 Degrader-1 |
PROTACs | PROTAC |
PROTAC IDO1 Degrader-1 is the first potent IDO1 (indoleamine 2,3-dioxygenase 1) degrader that hijacks IDO1 to CRBN E3 ligase to introduce IDO1 into UPS and eventually achieve ubiquitination and degradation (DC50=2.84 μM). PROTAC IDO1 Degrader-1 moderately improves the tumor-killing activity of H ER2 CAR-T cells[1]. PROTAC IDO1 Degrader-1 (compound 2c) (10 μM; 24 hours) notably decreases IDO1 level induced by IFN-γ[1].PROTAC IDO1 Degrader-1 and IFN-γ (5 ng/mL) are incubated with HeLa cells for 24... | |||
T10199 |
GNF-PF-3777
8-Nitrotryptanthrin |
IDO; Indoleamine 2,3-Dioxygenase (IDO) | Metabolism |
GNF-PF-3777 (8-Nitrotryptanthrin) 是人吲哚胺2,3-双加氧酶 2 (hIDO2) 抑制剂,能够降低IDO2活性,Ki=为 0.97 μM。 | |||
T9164 |
BMS-986242
BMS986242 |
IDO; Indoleamine 2,3-Dioxygenase (IDO) | Metabolism |
BMS-986242 是具有口服具有活力、强效的、选择性的 indoleamine-2,3-dioxygenase 1 抑制剂,可用于研究癌症。 | |||
T4307 |
PF-06840003
EOS200271,PF 06840003 |
IDO; Indoleamine 2,3-Dioxygenase (IDO) | Metabolism |
PF-06840003 (EOS200271) 是口服具有活力的、选择性的IDO-1抑制剂,抑制 hIDO-1, dIDO-1和 mIDO-1 的IC50分别为 0.41 μM, 0.59 μM,和 1.5 μM。 | |||
T4532 |
Linrodostat
BMS-986205 |
IDO; Indoleamine 2,3-Dioxygenase (IDO) | Metabolism |
Linrodostat (BMS-986205) 是选择性的、不可逆的吲哚胺 2,3-双加氧酶 1(IDO1) 抑制剂,能够有效抑制 IDO1-HEK293 细胞,其IC50=1.1 nM。它在晚期癌症中具有良好的药理特性。 | |||
TQ0071 |
Navoximod
GDC-0919,NLG-919 |
Indoleamine 2,3-Dioxygenase (IDO) | Metabolism |
Navoximod (GDC-0919) 是 IDO(indoleamine-(2,3)-dioxygenase) 抑制剂,Ki=7 nM/,EC50=75 nM。 | |||
T1847 |
Necrostatin-1
Nec-1,Necrostatin 1 |
Indoleamine 2,3-Dioxygenase (IDO); Ferroptosis; Autophagy; RIP kinase | Apoptosis; Autophagy; Metabolism; NF-κB |
Necrostatin-1 (Nec-1) 是一种坏死性凋亡抑制剂和 RIP1 抑制剂,具有特异性。Necrostatin-1 抑制 TNF-α 诱导的坏死性凋亡。Necrostatin-1 也可以抑制 IDO。 | |||
T20513 |
IDO1-IN-1
IDO1 inhibitor 1,2 HzBTZ,2-肼基苯并噻唑,IDO1IN1,2-HzBTZ,IDO1-inhibitor-1 |
IDO | Metabolism |
IDO1-IN-1 (2 HzBTZ) 是一种吲哚胺 2,3-双加氧酶 1 (IDO1) 抑制剂。 | |||
T11624 | IDO1-IN-2 | IDO | Metabolism |
IDO1-IN-2 is a potent and selective IDO1 inhibitor with IC50s of 81 nM, 59 nM (mouse), and 28 nM (rat), respectively. It has anti-cancer activity. | |||
T6543 |
Indoximod
NLG-8189,Indoximod (NLG-8189),1-Methyl-D-tryptophan,吲哚莫德 |
Indoleamine 2,3-Dioxygenase (IDO) | Metabolism |
Indoximod (Indoximod (NLG-8189)) 是一种具有口服具有活力的吲哚胺2,3-双加氧酶(IDO) 途径抑制剂。它在调节 mTOR 中充当 Trp 模拟物。它是一种可用于癌症研究的免疫代谢佐剂。 | |||
T61789 |
IDO1-IN-14
|
Others | Others |
IDO1-IN-14 (compound 4a) is a highly effective inhibitor of the IDO1 enzyme, exhibiting an IC50 value of 396.9 nM. Additionally, IDO1-IN-14 demonstrates excellent suppression of cellular IDO1 activity, as observed in HeLa cells with an EC50 value of 3393 nM [1]. | |||
T78687 |
IDO1-IN-21
|
Indoleamine 2,3-Dioxygenase (IDO) | Metabolism |
IDO1-IN-21(化合物10m)为IDO1抑制剂,其IC50值为0.64 μM。该化合物在小鼠体内可有效抑制肿瘤生长。 | |||
T82082 |
IDO1-IN-23
|
Indoleamine 2,3-Dioxygenase (IDO) | Metabolism |
IDO1-IN-23(化合物41)是一种有效的人类IDO1抑制剂,具备13 μM的IC50值。 | |||
T61944 |
IDO1-IN-15
|
Others | Others |
IDO1-IN-15 是有效的IDO1抑制剂,IC50为127 nM。IDO1-IN-15与Epacadostat 在体外对抗 IDO1 酶的效力相当。 | |||
T63814 |
IDO2-IN-1
|
Others | Others |
IDO2-IN-1 是一种口服活性的强效IDO2抑制剂,其IC50为112 nM。该化合物适用于炎症性自身免疫研究。 | |||
T74507 |
IDO1-IN-20
|
Others | Others |
IDO1-IN-20是一种催化色氨酸氧化代谢的酶,能在肿瘤微环境中对肿瘤进行免疫抑制。 | |||
T11625 |
IDO1 and HDAC1 Inhibitor
|
Others | Others |
IDO1 and HDAC1 Inhibitor is a dual IDO1 and HDAC1 inhibitor (IC50s: 69.0 nM and 66.5 nM). | |||
T63034 |
IDO1-IN-13
|
Others | Others |
IDO1-IN-13 (compound 27a) 是一种 IDO1 的有效抑制剂 (IC50: 61.6 nM)。IDO1-IN-13 能够抑制细胞 IDO1,对 HeLa 的 EC50 值为 30 nM。在 SK-OV-3 异种移植肿瘤组织中,IDO1-IN-13 减少了 51% 的 kyn/trp 比率。 | |||
T63082 |
IDO1-IN-19
|
Others | Others |
IDO1-IN-19 (Compound 17) 是一种 IDO1 的有效抑制剂,具有潜力进行癌症疾病的研究。 | |||
T63780 |
IDO1-IN-16
|
Others | Others |
IDO1-IN-16 (I-1) 是一种 IDO1 抑制剂,能够靶向holo-IDO1 (IC50: 127 nM)。 | |||
T73111 |
IDO1-IN-17
|
Others | Others |
IDO1-IN-17 (I-4) 是IDO1的抑制剂,其在 hela 细胞中的IC50值为 0.44 μM。 | |||
T12801 |
(S)-IDO1-IN-5
|
Others | Others |
(S)-IDO1-IN-5 is an active S-isomer of IDO1-IN-5. (S)-IDO1-IN-5 binds to IDOL(IC50 value less than 1.5 µΜ). |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T4S0051 |
Coptisine sulfate
|
Indoleamine 2,3-Dioxygenase (IDO) | Metabolism |
Coptisine Sulfate 是一种从黄连中分离到的生物碱,是非竞争性的IDO 抑制剂,Ki=为 5.8 μM,IC50=6.3 μM。 | |||
T3S1967 |
(S)-Indoximod
N-ME-Tryptophan,Abrine,相思豆碱,L-Abrine |
Others; Indoleamine 2,3-Dioxygenase (IDO) | Metabolism; Others |
(S)-Indoximod (L-Abrine) 是一种吲哚胺-2,3-双加氧酶 (IDO) 抑制剂,可用于研究癌症。 | |||
T5S0053 |
Coptisine
黄连碱,Coptisin |
Indoleamine 2,3-Dioxygenase (IDO) | Metabolism |
Coptisine (Coptisin) 是一种从黄连中分离到的生物碱,是非竞争性的IDO 抑制剂,Ki=为 5.8 μM,IC50=6.3 μM。 | |||
T2718 |
Palmatine chloride
|
Others; Indoleamine 2,3-Dioxygenase (IDO); Aurora Kinase | Cell Cycle/Checkpoint; Chromatin/Epigenetic; Metabolism; Others |
Palmatine chloride 是口服具有活力的不可逆 IDO-1抑制剂。它能够减轻结肠损伤,预防肠道菌群失调和调节色氨酸分解代谢,并改善 DSS 诱发的结肠炎。 | |||
T5S0802 |
Palmatine
巴马汀,Berbericinine,Burasaine |
Indoleamine 2,3-Dioxygenase (IDO); AChR; AChE; Aurora Kinase | Cell Cycle/Checkpoint; Chromatin/Epigenetic; Metabolism; Neuroscience |
Palmatine (Burasaine) 是口服具有活力的、不可逆IDO-1抑制剂。它可以减轻结肠损伤,预防肠道菌群失调和调节色氨酸分解代谢,从而改善DSS (Dextran Sulphate Sodium Salt) 诱发的结肠炎。它有用于结肠炎的研究潜力。 | |||
T5S0056 |
Coptisine chloride
盐酸黄连碱,氯化黄连碱,Q-100696,NSC-119754 |
Indoleamine 2,3-Dioxygenase (IDO); Influenza Virus; Antibacterial | Metabolism; Microbiology/Virology |
Coptisine chloride (NSC-119754) 是从黄连中分离到的一种生物碱,是一种非竞争性 IDO 抑制剂,Ki 值为 5.8 μM,IC50值为 6.3 μM。它是一种 H1N1 神经氨酸酶抑制剂,可用于甲型流感病毒感染,IC50为 104.6 μg/mL。 | |||
T8214 |
Kushenol E
苦参醇E,Flemiphilippinin D |
IDO; Indoleamine 2,3-Dioxygenase (IDO) | Metabolism |
Kushenol E (Flemiphilippinin D) 是一种分离自Sophora flavescens 中的类黄酮,是一种IDO1的非竞争性抑制剂,其IC50=7.7 µM,Ki=为 9.5 µM,具有抗肿瘤特性。 | |||
T7916 |
4-Acetamidobenzenesulfonyl azide
|
Others | Others |
4-Acetamidobenzenesulfonyl azide 用于各种科学研究应用,包括药物、肽和其他生物活性分子的合成,也被用作聚合反应和聚合物合成中的催化剂。 | |||
T19962 |
Xyloidone
NSC-106453,NSC106453,Dehydro-α-lapachone,NSC 106453,Dehydrolapachone,脱氢拉帕醌,NSC 629748 |
Antifungal | Microbiology/Virology |
Xyloidone (NSC-106453) 具有抗真菌活性,在 0.4-33.3 mg/L 的范围内完全抑制 B. cinerea、Colletotrichum acutatum Simmonds、Colletotrichum gloeosporioides Simmonds、M. grisea 和 Pythium ultimum Trow 的菌丝生长。 | |||
T4728 |
4-Acetamidobutanoic acid
N-acetyl GABA,4-ACETAMIDOBUTYRIC ACID,4-乙酰氨基丁酸 |
GABA Receptor; Endogenous Metabolite; Antibacterial | Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience |
4-Acetamidobutanoic acid (4-ACETAMIDOBUTYRIC ACID) 可在血液、粪便和尿液以及人体前列腺组织中找到,也存在于从酵母到人类的所有真核生物中。它是GABA 衍生物,具有抗氧化和抗菌活性。 | |||
T5085 |
Pyridoxal 5'-phosphate hydrate
Codecarboxylase,Pyridoxal 5'-phosphate hydrate(1:x),5-磷酸吡多醛水合物,PLP,Pyridoxal 5'-phosphate hydrate |
Others; Endogenous Metabolite | Metabolism; Others |
Pyridoxal 5'-phosphate hydrate (PLP) 是内源性代谢产物的一种。 | |||
T0436 |
6-Acetamidohexanoic acid
醋氨己酸,6-Acetamidocaproic acid,Acexamic Acid |
Amino Acids and Derivatives; COX | Immunology/Inflammation; Metabolism; Neuroscience |
6-Acetamidohexanoic acid (Acexamic Acid) 是一种医药中间体。 | |||
T0076 |
Paliperidone
9-羟基利培酮,帕潘立酮,9-hydroxyrisperidone |
Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor; Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Paliperidone (9-hydroxyrisperidone) 是 Risperidone 的主要活性代谢产物,是多巴胺 D2 拮抗剂和5-HT2A 拮抗剂。它用作非典型抗精神病药,用于精神分裂症的急性及维持治疗。它对α1和α2肾上腺素能受体和 H1组胺能受体也有拮抗作用。 | |||
T4805 |
α-Pyridone
2-Hydroxypyridine,2-羟基吡啶 |
Others; Endogenous Metabolite | Metabolism; Others |
α-Pyridone (2-Hydroxypyridine) 是内源性代谢产物的一种。 | |||
TN1035 |
Irisolidone
尼泊尔鸢尾异黄酮,葛花苷元 |
IL Receptor; NF-κB; Chloride channel | Immunology/Inflammation; Membrane transporter/Ion channel; NF-κB |
Irisolidone 是葛根花中的一种异黄酮,具有较强的保肝活性。它是一种有效的体积调节阴离子通道 (VRAC) 电流抑制剂,有高效阻断作用,IC50 为 5-13 μM。 | |||
T9279 |
nerolidol acetate
|
Others | Others |
Nerolidol acetate是一种具有抗癌、抗炎、抗菌和抗虫的活性的天然倍半萜。Nerolidol acetate可抑制寄生虫活动,抑制吸血虫病、线虫病以及疟疾等。Nerolidol acetate可保护细胞免受脂质、蛋白质和 DNA 的氧化损伤,对小鼠海马神经细胞具有保护作用。 | |||
T5226 |
2-(2-Methylbenzamido)acetic acid
2-Methylhippuric acid,2-甲基马尿酸,O-Toluric acid,N-(O-Toluoyl)glycine |
Others; Endogenous Metabolite | Metabolism; Others |
2-(2-Methylbenzamido)acetic acid (O-Toluric acid) 是一种能够在尿液中检测到的代谢物。 | |||
T5217 |
2-(2-Phenylacetamido)acetic acid
Phenaceturic acid,Phenyl-ac-Gly-OH,苯乙酰甘氨酸,Phenylacetyl glycine |
Others; Endogenous Metabolite | Metabolism; Others |
Phenyl-ac-Gly-OH 是内源性代谢产物的一种,可激活 β2AR,可用于研究缺血/再灌注引起的心脏损伤。 | |||
T6795 |
Carbidopa
卡比多巴,(S)-(-)-Carbidopa,Lodosyn |
Decarboxylase; Aryl Hydrocarbon Receptor | Immunology/Inflammation; Metabolism; Others |
Carbidopa (Lodosyn) 是一种选择性芳香烃受体(AhR)调节剂,是外周型脱羧酶抑制剂,抑制胰腺癌细胞和肿瘤生长,可用于帕金森病的研究。 | |||
T5558 |
Chelidonic acid
Jervaic acid,Jerva acid,白屈菜酸,γ-Pyrone-2,6-dicarboxylic acid |
NF-κB; Caspase | Apoptosis; NF-κB; Proteases/Proteasome |
Chelidonic acid (Jervaic acid) 是从白屈菜中分到的酸类物质,用作温和的镇痛剂、抗菌剂和中枢神经系统镇静剂。它是谷氨酸脱羧酶抑制剂,Ki 值为 1.2 μM。它可能通过抑制 NF-κB 和caspase-1来降低 IL-6 的产生抗炎作用。 | |||
T0973 |
Pyridoxine
吡哆醇,Pyridoxol,Vitamin B6,Gravidox,吡多素(维生素B6) |
PLK; Nrf2; Endogenous Metabolite | Cell Cycle/Checkpoint; Immunology/Inflammation; Metabolism |
Pyridoxine (Vitamin B6) 是一种吡啶衍生物,通过 Nrf-2/HO-1 途径发挥抗氧化作用,作用于阿尔茨海默病细胞模型。 | |||
T3578 |
Pyridoxal phosphate
PLP,PAL-P,磷酸吡哆醛,pyridoxal 5'-phosphate,Pyridoxyl phosphate,Pyridoxal 5′-phosphate,Vitamin B6 phosphate |
Reverse Transcriptase; Endogenous Metabolite | Metabolism; Microbiology/Virology |
Pyridoxal phosphate (Vitamin B6 phosphate) 是维生素 B6 的活性形式,可抑制逆转录酶活性,用于研究迟发性运动障碍症。 | |||
T12588 |
Pyridoxylamine
pyridoxamine,吡多胺 |
Endogenous Metabolite | Metabolism |
Pyridoxylamine (pyridoxamine) 是脂质化终产物和糖基化终产物抑制剂,能够防止糖尿病引起的视网膜血管病变。 | |||
T5S0055 |
Chelidonine
Helidonine,Khelidonin,白屈菜碱,Stylophorin |
Apoptosis; Others; Influenza Virus | Apoptosis; Microbiology/Virology; Others |
Chelidonine (Stylophorin) 是白屈菜中的一种异喹啉生物碱,有抗肿瘤和抗病毒作用。它可导致细胞周期 G2/M 停滞,诱导 caspase 依赖和非依赖性的细胞凋亡。 | |||
T2931 |
2-Amino-5-ureidopentanoic acid
DL-Citrulline,Citrulline,瓜氨酸 |
Others; Endogenous Metabolite | Metabolism; Others |
2-Amino-5-ureidopentanoic acid (Citrulline) 存在于肝脏中,不是蛋白质的构成成分,为人体脲循环的一个重要中间物,可与鸟氨酸、精氨酸合用治疗高氨血症。 | |||
T2790 |
Oridonin
NSC-250682,Rubescenin,冬凌草甲素,Isodonol,Rubescensin A |
Akt; Antibacterial | Cytoskeletal Signaling; Microbiology/Virology; PI3K/Akt/mTOR signaling |
Oridonin (NSC-250682) 是从Rabdosia rubescens 中得到的二萜,是一种AKT 抑制剂,对 AKT1 和 AKT2 的IC50值分别为 8.4 和 8.9 μM,具有抗菌、抗炎、抗肿瘤等功效。 | |||
T20003 |
Acridone
|
Antibacterial; ABC | Membrane transporter/Ion channel; Microbiology/Virology |
Acridone 具有抗菌、抗疟、抗病毒和抗肿瘤活性。它可诱导细胞凋亡,抑制 ABCG2 蛋白,并调节激素水平。 | |||
T36473 |
trans-Nerolidol
|
Antifungal | Microbiology/Virology |
trans-Nerolidol 是从撒哈拉瓦莲属植物的地上部分分离出来的倍半萜醇,具有抗真菌活性。trans-Nerolidol 以剂量依赖性方式抑制细胞增殖,诱导细胞周期停滞在 G1 期 | |||
T7324 |
Chelidonine hydrochloride
|
Others | Others |
Chelidonine hydrochloride 是 Chelidonium majus 的生物碱之一,具有广泛的药理活性。 | |||
T4754 |
Pyridoxylamine dihydrochloride
盐酸吡多胺,Pyridorin,Pyridoxamine dihydrochloride |
Others; Endogenous Metabolite | Metabolism; Others |
Pyridoxylamine dihydrochloride (Pyridorin) 是一种糖基化终产物和脂质化终产物抑制剂,能够防止糖尿病引起的视网膜血管病变。 | |||
T25114 |
Ascaridole
NSC-406266,NSC 406266,NSC406266 |
Parasite | Microbiology/Virology |
Ascaridole (NSC-406266) 可作为驱虫化合物,能驱除人体和植物中的寄生蠕虫(蠕虫),具有较弱的抗疟活性。 | |||
T4129 |
Arachidonic acid
Immunocytophyte,花生四烯酸,arachidonate,Immunocytophyt,Vevodar |
Others; Endogenous Metabolite | Metabolism; Others |
Arachidonic acid (Immunocytophyte) 属于天然产物,是一种不饱和的必需脂肪酸,是动物磷脂的成分。Arachidonic acid 由膳食亚油酸合成而成,是前列腺素、血栓素和白三烯生物合成的前体。 | |||
TN7032 |
4'-O-Methylpyridoxine
4-methoxymethylpyridoxine,Ginkgotoxin |
Antioxidant | oxidation-reduction |
4'-O-Methylpyridoxine(MPN)是从银杏叶中发现的维生素类化合物,具有抗氧化活性和细胞毒性。 | |||
T8083 |
Pyridoxal 5'-phosphate monohydrate
Pyridoxal phosphate monohydrate,Pyridoxal 5-phosphate monohydrate,5-磷酸吡哆醛 |
Others | Others |
Pyridoxal 5-phosphate monohydrate 是维生素B6的活性形式,也是多种酶的重要辅因子。它是维生素 B6 在细胞内磷酸化过程中最重要的辅酶变异体,能够与其他变异体(如 PNP 、 PMP)发生互换。 | |||
T0973L |
Pyridoxine hydrochloride
Pyridoxine HCl,吡哆醇盐酸盐,Pyridoxol (hydrochloride),吡哆醇盐酸盐(维生素B6),Vitamin B6 (hydrochloride),Vitamin B6 |
Nrf2; Endogenous Metabolite | Immunology/Inflammation; Metabolism |
Pyridoxine hydrochloride (Vitamin B6) 是一种吡啶衍生物。在于阿尔茨海默病细胞模型中,通过 Nrf-2/HO-1 途径发挥抗氧化作用。 | |||
T4761 |
Pyridoxal hydrochloride
|
Others; Endogenous Metabolite | Metabolism; Others |
Pyridoxal hydrochloride 是内源性代谢产物的一种。 | |||
T4107 |
4-Pyridoxic Acid
4-吡哆酸,Pyridoxic Acid,4-Pyridoxinsaeure |
Endogenous Metabolite | Metabolism |
4-Pyridoxic Acid (4-Pyridoxinsaeure) 是一种维生素B6的分解代谢产物,从尿液中分泌得到。 | |||
TN1819 |
Kaempferol 3-neohesperidoside
Kaempferol 3-O-neohesperidoside,堪非醇 3-新橙皮糖苷 |
GSK-3; MEK; PI3K | MAPK; PI3K/Akt/mTOR signaling; Stem Cells |
Kaempferol 3-neohesperidoside (Kaempferol 3-O-neohesperidoside) 是一种类黄酮,对大鼠比目鱼肌具有拟胰岛素作用。 | |||
T3799 |
Isorhamnetin-3-O-neohespeidoside
Isorhamnetin 3-O-neohesperidin,异鼠李素-3-O-新橙皮糖苷,Isorhamnetin 3-O-neohesperoside,Calendoflavoside,异鼠李素-3-O-新橙皮苷 |
Antioxidant | oxidation-reduction |
Isorhamnetin-3-O-neohespeidoside (Calendoflavoside) 是一种黄酮类化合物,分离自Pollen typhae 中。 | |||
T4919 |
Ureidopropionic acid
Carbamoyl-b-alanine,3-酰脲丙酸,3-Ureidopropionic acid |
Endogenous Metabolite | Metabolism |
Ureidopropionic acid (3-Ureidopropionic acid) 是尿嘧啶代谢的中间体。更具体地说,它是二氢尿嘧啶的分解产物,由二氢嘧啶酶产生。它通过β -脲丙酸酶进一步分解为β -丙氨酸。尿素丙酸本质上是β -丙氨酸的尿素衍生物。高水平的尿丙酸存在于β -尿丙酸酶(UP)缺乏的个体中。嘧啶代谢中的酶缺乏与抗肿瘤药物5-氟尿嘧啶的严重毒性风险有关。 | |||
T4933 |
(S)-2-acetamido-4-amino-4-oxobutanoic acid
Nα-Acetyl-L-asparagine,N-乙酰-L-天门冬酰胺 |
Endogenous Metabolite | Metabolism |
(S)-2-acetamido-4-amino-4-oxobutanoic acid (Nα-Acetyl-L-asparagine),也称为acasn,属于一种内源性代谢产物。 | |||
T2S2172 |
nerolidol
(±)-Nerolidol,Peruviol,橙花叔醇 |
Others; Endogenous Metabolite; Antibacterial; Parasite; Antifungal | Metabolism; Microbiology/Virology; Others |
Nerolidol (Peruviol) 是天然膜活性倍半萜,有抗肿瘤、抗细菌、抗真菌和抗寄生虫活性。它对动物有镇静作用,氧化过程对神经元病理后果起关键作用。 | |||
T19885 |
Methyllucidone
|
||
Methyllucidone is an inhibitor of STAT3 that acts by regulating the expression of the protein tyrosine phosphatase MEG2. | |||
TN4928 |
Rutacridone
|
P450 | Metabolism |
Rutacridone has mutagenicity. | |||
T82325 |
Gentiiridosides A
|
||
Gentiiridosides A为从龙胆中提取的一种化合物,采用无水乙醇作为萃取溶剂。 | |||
T79980 |
Flaccidoside III
|
Glucosidase | Metabolism |
Flaccidoside III, 分离自黑种草(N. sativa)地上部分的一种类黄酮和三萜类化合物,具有抑制α-Glucosidase(IC50:256.7 μM)的活性,表现出潜在的抗氧化和抗糖尿病效应。 | |||
T15703 |
Lactimidomycin
|
Others | Others |
Lactimidomycin, isolated from Streptomyces, is an inhibitor of eukaryotic translation elongation. It is also a potent and non-toxic inhibitor of dengue virus 2 and other RNA viruses. Lactimidomycin has an antiproliferative effect on tumor cell lines. It i | |||
TN2590 |
11alpha,12alpha-Oxidotaraxerol palmitate
|
Others | Others |
11alpha,12alpha-Oxidotaraxerol palmitate shows selective cytotoxicity against HCT-8, Bel-7402, BGC-823, A549 and A2780. | |||
TN6244 |
Hainanolidol
|
||
Hainanolidol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6244,CAS号为 73213-63-5。 | |||
T72730 |
D-Isofloridoside
|
Others | Others |
D-Isofloridoside 是多糖前体之一,具有清除自由基、抑制ROS 表达、抑制MMP-2和MMP-9的活性。 | |||
------------------------ 更多 ------------------------ |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02928 |
IDO Protein, Human, Recombinant
IDO-1,Indoleamine 2,3‑dioxygenase,indoleamine 2,3-d... |
Human | E. coli |
IDO Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 45.2 kDa and the accession number is A0A348GSI3. | |||
TMPY-01821 |
IDO Protein, Human, Recombinant (His)
IDO,indoleamine 2,3-dioxygenase 1,Indoleamine 2,3‑d... |
Human | E. coli |
IDO Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 46 kDa and the accession number is P14902-1. | |||
TMPY-06772 |
IDO Protein, Mouse, Recombinant (His)
Indo,indoleamine 2,3-dioxygenase 1,Ido |
Mouse | E. coli |
IDO Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 46.47 kDa and the accession number is P28776. | |||
TMPY-02803 |
IDO2 Protein, Human, Recombinant (His)
indoleamine 2,3-dioxygenase 2,INDOL1 |
Human | E. coli |
IDO2 belongs to the indoleamine 2,3-dioxygenase family. Indoleamine 2,3-dioxgyenase (IDO), is a cytosolic haem protein which, together with the hepatic enzyme tryptophan 2,3-dioxygenase, catalyzes the conversion of tryptophan and other indole derivatives to kynurenines. In addition to classic IDO (IDO1), a new variant, IDO2, has recently been described. IDO2 is expressed in the liver, small intestine, spleen, placenta, thymus, lung, brain, kidney, and colon. IDO is widely distributed in human ti... | |||
TMPY-00240 |
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) GP1/Glycoprotein Protein (His)
|
EBOV | HEK293 Cells |
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) GP1/Glycoprotein Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52.3 kDa and the accession number is X5HMX4. | |||
TMPY-01502 |
Influenza A H5N3 (A/duck/Hokkaido/167/2007) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H5N3 | HEK293 Cells |
Influenza A H5N3 (A/duck/Hokkaido/167/2007) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59 kDa and the accession number is B1AHS0. | |||
TMPH-00084 |
Dehydrin Xero 2 Protein, Arabidopsis thaliana, Recombinant (His & Myc)
Low-temperature-induced protein LTI30,LTI30,XERO2,Dehydrin X... |
Arabidopsis thaliana | E. coli |
Dehydrin Xero 2 Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.4 kDa and the accession number is P42758. | |||
TMPH-00082 |
DREB2C Protein, Arabidopsis thaliana, Recombinant (His)
Dehydration-responsive element-binding protein 2C,DREB2C,ERF... |
Arabidopsis thaliana | E. coli |
Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'. Binding to the C-repeat/DRE element mediates high salinity- and abscisic acid-inducible transcription. DREB2C Protein, Arabidopsis thaliana, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 43.9 kDa and the accession number is Q8LFR2. | |||
TMPH-00075 |
At1g09870/F21M12_26 Protein, Arabidopsis thaliana, Recombinant (E. coli, His)
Multiple inositol polyphosphate phosphatase 1,2,3-bisphospho... |
Arabidopsis thaliana | E. coli |
At1g09870/F21M12_26 Protein, Arabidopsis thaliana, Recombinant (E. coli, His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 58.8 kDa and the accession number is Q941B2. | |||
TMPH-00081 |
CDKB1-2 Protein, Arabidopsis thaliana, Recombinant (His)
CDKB1-2,CDKB1;2,Cyclin-dependent kinase B1-2 |
Arabidopsis thaliana | P. pastoris (Yeast) |
Together with CDKB1-1, promotes both the last division in the stomatal cell lineage as well as the number of stomata. In collaboration with MYB124 and MYB88, restrict the G1/S transition and chloroplast and nuclear number during stomatal formation, and normally maintain fate and developmental progression throughout the stomatal cell lineage. CDKB1-2 Protein, Arabidopsis thaliana, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 37.6 kDa and the accessio... | |||
TMPH-00116 |
UGT89C1 Protein, Arabidopsis thaliana, Recombinant (Yeast, His)
UDP-rhamnose: flavonol 7-O-rhamnosyltransferase,UDP-glycosyl... |
Arabidopsis thaliana | P. pastoris (Yeast) |
UGT89C1 Protein, Arabidopsis thaliana, Recombinant (Yeast, His) is expressed in yeast with N-10xHis tag. The predicted molecular weight is 50.6 kDa and the accession number is Q9LNE6. | |||
TMPH-00077 |
IAA17 Protein, Arabidopsis thaliana, Recombinant (His & Myc)
IAA17,Auxin response 3,Indoleacetic acid-induced protein 17,... |
Arabidopsis thaliana | E. coli |
Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin-responsive promoter element (AuxRE). Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression. IAA17 Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in E.... | |||
TMPH-00086 |
EPFL9 Protein, Arabidopsis thaliana, Recombinant (His)
EPIDERMAL PATTERNING FACTOR-like protein 9,EPFL9 |
Arabidopsis thaliana | E. coli |
Positively regulates stomatal density and patterning. Acts by competing with EPF2 (AC Q8LC53) for the same receptors, ERECTA (AC Q42371) and TMM (AC Q9SSD1). Not cleaved by the protease CRSP (AC Q9LNU1). EPFL9 Protein, Arabidopsis thaliana, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 14.2 kDa and the accession number is Q9SV72. | |||
TMPH-00099 |
NDK1 Protein, Arabidopsis thaliana, Recombinant (His & Myc)
Nucleoside diphosphate kinase 1,NDK1,Nucleoside diphosphate ... |
Arabidopsis thaliana | P. pastoris (Yeast) |
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Plays a role in response to reactive oxygen species (ROS) stress. NDK1 Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in yeast with N-10xHis and C-Myc tag. The predicted molecular weight is 20.5 kDa and the accession number is P39207. | |||
TMPH-00114 |
UGT88A1 Protein, Arabidopsis thaliana, Recombinant (His & Myc)
UGT88A1,UDP-glycosyltransferase 88A1 |
Arabidopsis thaliana | Baculovirus Insect Cells |
Possesses low quercetin 3-O-glucosyltransferase, 7-O-glucosyltransferase, 3'-O-glucosyltransferase and 4'-O-glucosyltransferase activities in vitro. UGT88A1 Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 55.1 kDa and the accession number is Q9LK73. | |||
TMPH-02812 |
Nidogen-1 Protein, Mouse, Recombinant (His)
Nid1,Nidogen-1,Entactin |
Mouse | P. pastoris (Yeast) |
Sulfated glycoprotein widely distributed in basement membranes and tightly associated with laminin. Also binds to collagen IV and perlecan. It probably has a role in cell-extracellular matrix interactions. | |||
TMPH-00105 |
RGF1 Protein, Arabidopsis thaliana, Recombinant (GST)
Protein GOLVEN 11,Root meristem growth factor 1,GLV11,CLAVAT... |
Arabidopsis thaliana | E. coli |
RGF1 Protein, Arabidopsis thaliana, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 28.2 kDa and the accession number is Q3E880. | |||
TMPH-00101 |
PDLP7 Protein, Arabidopsis thaliana, Recombinant (His & SUMO)
PDLP7,Cysteine-rich repeat secretory protein 60,Plasmodesmat... |
Arabidopsis thaliana | E. coli |
Modulates cell-to-cell trafficking. PDLP7 Protein, Arabidopsis thaliana, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 41.3 kDa and the accession number is Q0WPN8. | |||
TMPY-00255 |
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) GP2/Glycoprotein Protein (Fc)
|
EBOV | HEK293 Cells |
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) GP2/Glycoprotein Protein (Fc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 43.4 kDa and the accession number is X5HMX4. | |||
TMPY-00043 |
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP Protein (His)
|
EBOV | Baculovirus Insect Cells |
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 69.3 kDa and the accession number is X5HMX4. | |||
TMPY-01503 |
Influenza A H5N3 (A/duck/Hokkaido/167/2007) Hemagglutinin/HA1 Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H5N3 | HEK293 Cells |
Influenza A H5N3 (A/duck/Hokkaido/167/2007) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38 kDa and the accession number is B1AHS0. | |||
TMPY-00098 |
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP-RBD Protein (Fc)
|
EBOV | HEK293 Cells |
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP-RBD Protein (Fc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 57.6 kDa and the accession number is X5HMX4. | |||
TMPY-00292 |
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP (Virion spike glycoprotein) Protein (His)
|
EBOV | HEK293 Cells |
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP (Virion spike glycoprotein) Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.8 kDa and the accession number is X5HMX4. | |||
TMPH-00083 |
Dehydrin ERD14 Protein, Arabidopsis thaliana, Recombinant (His & Myc)
ERD14,Dehydrin ERD14 |
Arabidopsis thaliana | E. coli |
Intrinsically disordered protein acting as a chaperone. Prevents heat-induced aggregation and/or inactivation of various substrates. Binds to acidic phospholipid vesicles without affecting membrane fluidity. Dehydrin ERD14 Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.1 kDa and the accession number is P42763. | |||
TMPH-00098 |
AtAER Protein, Arabidopsis thaliana, Recombinant
P1-ZCr,NADPH-azodicarbonyl/quinone reductase,NADPH-dependent... |
Arabidopsis thaliana | E. coli |
AtAER Protein, Arabidopsis thaliana, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 38.1 kDa and the accession number is Q39172. | |||
TMPH-00108 |
UBC11 Protein, Arabidopsis thaliana, Recombinant (His)
Ubiquitin-conjugating enzyme E2-17 kDa 11,Ubiquitin-conjugat... |
Arabidopsis thaliana | E. coli |
Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. UBC11 Protein, Arabidopsis thaliana, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 20.6 kDa and the accession number is P35134. | |||
TMPH-00113 |
UGT78D1 Protein, Arabidopsis thaliana, Recombinant (His)
UGT78D1,UDP-glycosyltransferase 78D1,UDP-rhamnose:flavonol 3... |
Arabidopsis thaliana | E. coli |
Flavonol 3-O-rhamnosyltransferase that catalyzes the transfer of rhamnose from UDP-rhamnose to the 3-OH position of kaempferol and quercetin. Possesses low quercetin 3-O-glucosyltransferase activity in vitro. UGT78D1 Protein, Arabidopsis thaliana, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 55.6 kDa and the accession number is Q9S9P6. | |||
TMPH-00074 |
GlcNAcT-I Protein, Arabidopsis thaliana, Recombinant (His)
N-acetylglucosaminyltransferase I,Protein COMPLEX GLYCAN LES... |
Arabidopsis thaliana | Baculovirus Insect Cells |
Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans. Required for normal root growth and morphology. GlcNAcT-I Protein, Arabidopsis thaliana, Recombinant (His) is expressed in Baculovirus insect cells with C-6xHis tag. The predicted molecular weight is 51.6 kDa and the accession number is Q9XGM8. | |||
TMPH-00107 |
UBC10 Protein, Arabidopsis thaliana, Recombinant (His)
Ubiquitin carrier protein 10/12,Ubiquitin-conjugating enzyme... |
Arabidopsis thaliana | E. coli |
Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. UBC10 Protein, Arabidopsis thaliana, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 20.6 kDa and the accession number is P35133. | |||
TMPH-00110 |
UGT72B1 Protein, Arabidopsis thaliana, Recombinant (His & Myc)
Probable hydroquinone glucosyltransferase,Arbutin synthase,U... |
Arabidopsis thaliana | E. coli |
Bifunctional O-glycosyltransferase and N-glycosyltransferase that can detoxify xenobiotics. Possesses high activity to metabolize the persistent pollutants 2,4,5-trichlorophenol (TCP) and 3,4-dichloroaniline (DCA). Also active on benzoates and benzoate derivatives in vitro. UGT72B1 Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 60.4 kDa and the accession number is Q9M156. | |||
TMPH-00100 |
OSM34 Protein, Arabidopsis thaliana, Recombinant (His & Myc & SUMO)
Osmotin-like protein OSM34,OSM34 |
Arabidopsis thaliana | E. coli |
OSM34 Protein, Arabidopsis thaliana, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 44.4 kDa and the accession number is P50700. | |||
TMPH-03608 |
Phosphinothricin N-acetyltransferase Protein, S. viridochromogenes, Recombinant (His)
Phosphinothricin N-acetyltransferase,Phosphinothricin-resist... |
Streptomyces viridochromogenes | P. pastoris (Yeast) |
Inactivates phosphinothricin (PPT) by transfer of an acetyl group from acetyl CoA. This enzyme is an effector of phosphinothricin tripeptide (PTT or bialaphos) resistance. Phosphinothricin N-acetyltransferase Protein, S. viridochromogenes, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 22.6 kDa and the accession number is Q57146. | |||
TMPH-00094 |
HSP21, chloroplastic Protein, Arabidopsis thaliana, Recombinant (His & Myc)
25.3 kDa heat shock protein, chloroplastic,HSP21,Heat shock ... |
Arabidopsis thaliana | E. coli |
Chaperone protein required for seedling and chloroplast development under heat stress, probably by maintaining plastid-encoded RNA polymerase (PEP)-dependent transcription. HSP21, chloroplastic Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.4 kDa and the accession number is P31170. | |||
TMPH-00112 |
UGT72E2 Protein, Arabidopsis thaliana, Recombinant (Baculovirus, His & Myc)
UGT72E2,Hydroxycinnamate 4-beta-glucosyltransferase UGT72E2,... |
Arabidopsis thaliana | Baculovirus Insect Cells |
Involved in the O-glucosylation of monolignols (alcohol monomers of lignin). Glucosylates coniferyl alcohol to form coniferyl alcohol 4-O-glucoside. Glucosylates sinapyl alcohol to form sinapyl alcohol 4-O-glucoside. Glucosylates coniferyl aldehyde to form coniferyl aldehyde 4-O-glucoside. Glucosylates sinapyl aldehyde to form sinapyl aldehyde 4-O-glucoside. Possesses low activity with sinapate and ferulate as substrates. UGT72E2 Protein, Arabidopsis thaliana, Recombinant (Baculovirus, His & Myc... | |||
TMPY-00102 |
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP-RBD Protein (His)
|
EBOV | HEK293 Cells |
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP-RBD Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.3 kDa and the accession number is X5HMX4. | |||
TMPY-00219 |
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) VP24 Protein (His)
VP24 Protein |
EBOV | E. coli |
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) VP24 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 28.5 kDa and the accession number is L7QHW5. | |||
TMPH-00071 |
AtHsp23.6 Protein, Arabidopsis thaliana, Recombinant (His)
23.6 kDa heat shock protein, mitochondrial,AtHsp23.6,HSP23.6 |
Arabidopsis thaliana | E. coli |
AtHsp23.6 Protein, Arabidopsis thaliana, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 24.4 kDa and the accession number is Q96331. | |||
TMPH-00076 |
At1g09870/F21M12_26 Protein, Arabidopsis thaliana, Recombinant (Baculovirus, His)
2,3-bisphosphoglycerate 3-phosphatase,Multiple inositol poly... |
Arabidopsis thaliana | Baculovirus Insect Cells |
At1g09870/F21M12_26 Protein, Arabidopsis thaliana, Recombinant (Baculovirus, His) is expressed in Baculovirus insect cells with N-10xHis tag. The predicted molecular weight is 55.2 kDa and the accession number is Q941B2. | |||
TMPH-03075 |
3FTx-Oxy6 Protein, Oxyuranus microlepidotus, Recombinant (His & Myc & SUMO)
Three-finger toxin 3FTx-Oxy6 |
Oxyuranus microlepidotus | E. coli |
3FTx-Oxy6 Protein, Oxyuranus microlepidotus, Recombinant (His & Myc & SUMO) is expressed in E. coli. | |||
TMPH-00073 |
ADH2 Protein, Arabidopsis thaliana, Recombinant (His)
GSH-FDH,Glutathione-dependent formaldehyde dehydrogenase,Alc... |
Arabidopsis thaliana | E. coli |
Plays a central role in formaldehyde detoxification. ADH2 Protein, Arabidopsis thaliana, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 44.7 kDa and the accession number is Q96533. | |||
TMPH-00109 |
UBC8 Protein, Arabidopsis thaliana, Recombinant (His & Myc)
E2 ubiquitin-conjugating enzyme 8,Ubiquitin carrier protein ... |
Arabidopsis thaliana | E. coli |
Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. UBC8 Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 24.0 kDa and the accession number is P35131. | |||
TMPH-00103 |
Probable sarcosine oxidase Protein, Arabidopsis thaliana, Recombinant (His)
Probable sarcosine oxidase |
Arabidopsis thaliana | E. coli |
N/A. Probable sarcosine oxidase Protein, Arabidopsis thaliana, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 49.7 kDa and the accession number is Q9SJA7. | |||
TMPH-00087 |
Expansin-A1 Protein, Arabidopsis thaliana, Recombinant (His & Myc)
Expansin-A1,Alpha-expansin-1,EXPA1,Ath-ExpAlpha-1.2 |
Arabidopsis thaliana | E. coli |
Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found. Expansin-A1 Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 32.2 kDa and the accession number is Q9C554. | |||
TMPH-00089 |
SPT16 Protein, Arabidopsis thaliana, Recombinant (His & SUMO)
Facilitates chromatin transcription complex subunit SPT16,FA... |
Arabidopsis thaliana | E. coli |
SPT16 Protein, Arabidopsis thaliana, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 36.9 kDa and the accession number is O82491. | |||
TMPH-00092 |
FLS1 Protein, Arabidopsis thaliana, Recombinant (His & Myc)
FLS 1,FLS1,Flavonol synthase/flavanone 3-hydroxylase |
Arabidopsis thaliana | E. coli |
Catalyzes the formation of flavonols from dihydroflavonols. It can act on dihydrokaempferol to produce kaempferol, on dihydroquercetin to produce quercitin and on dihydromyricetin to produce myricetin. In vitro catalyzes the oxidation of both enantiomers of naringenin to give both cis- and trans-dihydrokaempferol. FLS1 Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 43.3 kDa and the ac... | |||
TMPY-00245 |
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Makona-Kissidougou-C15) GP/Glycoprotein Protein (His)
|
EBOV | HEK293 Cells |
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Makona-Kissidougou-C15) GP/Glycoprotein Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.3 kDa and the accession number is QDA39862.1. | |||
TMPY-00284 |
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) VP40/Matrix protein VP40 Protein (His & MBP)
|
EBOV | E. coli |
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) VP40/Matrix protein VP40 Protein (His & MBP) is expressed in E. coli expression system with His and MBP tag. The predicted molecular weight is 78.7 kDa and the accession number is X5H596. | |||
TMPH-00096 |
APX2, cytosolic Protein, Arabidopsis thaliana, Recombinant (His)
APX1b,APX2,L-ascorbate peroxidase 2, cytosolic,L-ascorbate p... |
Arabidopsis thaliana | E. coli |
APX2, cytosolic Protein, Arabidopsis thaliana, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 31.5 kDa and the accession number is Q1PER6. | |||
TMPH-00078 |
Beta-amylase 1, chloroplastic Protein, Arabidopsis thaliana, Recombinant (His & Myc)
1,4-alpha-D-glucan maltohydrolase,TRBAMY,TR-BAMY,BMY7,Thiore... |
Arabidopsis thaliana | E. coli |
Beta-amylase activity. Can use p-nitrophenyl maltopentaoside (PNPG5) as substrate only in reduced form. Can play a minor role in the starch degradation and maltose metabolism in chloroplasts during the night. More active on phosphorylated glucan. Interacts directly with starch or other alpha-1,4-glucan. Beta-amylase 1, chloroplastic Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 41.7 ... | |||
TMPH-00080 |
Catalase-2 Protein, Arabidopsis thaliana, Recombinant (His & SUMO)
Catalase-2,CAT,CAT2 |
Arabidopsis thaliana | E. coli |
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Catalase-2 Protein, Arabidopsis thaliana, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 72.9 kDa and the accession number is P25819. | |||
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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TMIH-0620 |
Arachidonoyl Ethanolamide-d4
AEA-d4 |
||
Deuterated anandamide, a synthetically modified version of anandamide where hydrogen atoms are replaced with deuterium (D), exhibits enhanced stability against oxidative degradation. This modification conserves the compound's pharmacological properties while prolonging its shelf life and efficacy in research applications, particularly in analytical and biochemical studies to elucidate the complex mechanisms of the endocannabinoid system. | |||
TMIH-0452 |
Primidone-d5
|
||
Primidone-d5 是 Primidone 的氘代化合物。 | |||
TMIH-0423 |
Penfluridol-d7
|
||
Penfluridol-d7 是 Penfluridol 的氘代化合物。Penfluridol 的 CAS 号为 26864-56-2。Penfluridol是一种高效的二苯类抗精神病药物。 | |||
T12587 |
Pyridostigmine-d6 bromide
Pyridostigmine D6 bromide,溴化吡啶斯的明 D6 |
Others | Others |
Pyridostigmine D6 bromide is the deuterium labeled Pyridostigmine, which is a parasympathomimetic and a reversible inhibitor of cholinesterase. | |||
T12035 |
Midodrine D6 hydrochloride
盐酸米多君 D6 |
Others | Others |
Midodrine D6 hydrochloride is a vasopressor/antihypotensive agent. | |||
TMIH-0038 |
3 Hydroxy Midostaurin Epimer 1-d5
CGP52421 Epimer 1-d5 |
||
3 Hydroxy Midostaurin Epimer 1-d5 是 3 Hydroxy Midostaurin Epimer 1 的氘代化合物。3 Hydroxy Midostaurin Epimer 1 的 CAS 号为 945260-14-0。 | |||
TMID-0277 |
4-AcetaMido-d3-antipyrine
|
||
4-AcetaMido-d3-antipyrine 是 4-AcetaMido-antipyrine 的氘代化合物。4-AcetaMido-antipyrine 的 CAS 号为 83-15-8。 | |||
TMID-0262 |
Lidocaine-d10 (N,N-diethyl-d10)
|
||
Lidocaine-d10 (N,N-diethyl-d10) 是 Lidocaine 的氘代化合物。Lidocaine 的 CAS 号为 137-58-6。Lidocaine是一种酰胺衍生物,抑制涉及复杂电压和依赖性的钠通道,可用于研究室性心律失常。它通过调节 miR-145 表达和进一步抑制MEK/ERK和NF-κB信号通路来减少胃癌细胞的生长,迁移和侵袭。 | |||
T10279 |
Alfacalcidol-D6
|
Others | Others |
Alfacalcidol-D6 is a deuterated Alfacalcidol. Alfacalcidol is a non-selective VDR activator medication. | |||
T12485 |
Pirfenidone-d5
AMR69 D5,Pirfenidone D5 |
Others | Others |
Pirfenidone D5 is a deuterium labeled Pirfenidone. Pirfenidone is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells. | |||
TMIH-0316 |
Lurasidone Inactive Metabolite 14326-d8
5β/6β-Hydroxy Lurasidone-d8 Hydrochloride (Mixture of Diastereomers) |
||
Lurasidone Inactive Metabolite 14326-d8 是 Lurasidone Inactive Metabolite 14326 的氘代化合物。Lurasidone Inactive Metabolite 14326 的 CAS 号为 186204-33-1。 | |||
TMIH-0515 |
Samidorphan-d5
|
||
Samidorphan-d5 是 Samidorphan 的氘代化合物。Samidorphan 的 CAS 号为 852626-89-2。 | |||
TMIH-0467 |
Pyridoxine-d3 Hydrochloride
|
||
Pyridoxine-d3 Hydrochloride 是 Pyridoxine Hydrochloride 的氘代化合物。 | |||
T12036 |
Midostaurin-D5
PKC412-D5,CGP 41251-D5 |
Others | Others |
Midostaurin-D5 is a deuterium labeled Midostaurin. | |||
TMIH-0314 |
Lurasidone-d8 HCl
|
||
Lurasidone-d8 HCl 是 Lurasidone HCl 的氘代化合物。Lurasidone HCl 的 CAS 号为 367514-88-3。Lurasidone hydrochloride 是多巴胺 D2和5-HT7的拮抗剂,IC50值分别为 1.68 和 0.495 nM,用于治疗精神分裂症和双相情感障碍。它也是5-HT1A受体的部分激动剂,IC50值为 6.75 nM。 | |||
TMID-0152 |
Pyridoxine-d2 HCl
|
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Pyridoxine-d2 HCl 是 Pyridoxine HCl 的氘代化合物。Pyridoxine HCl 的 CAS 号为 58-56-0。Pyridoxine hydrochloride 是一种吡啶衍生物。在于阿尔茨海默病细胞模型中,通过Nrf-2/HO-1 途径发挥抗氧化作用。 | |||
TMIH-0059 |
4-Pyridoxic Acid-d3 Hydrochloride
|
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4-Pyridoxic Acid-d3 Hydrochloride 是 4-Pyridoxic Acid Hydrochloride 的氘代化合物。4-Pyridoxic Acid Hydrochloride 的 CAS 号为 62511-95-9。 | |||
TMIH-0313 |
lurasidone-d8
|
||
lurasidone-d8 是 lurasidone 的氘代化合物。 | |||
TMIH-0465 |
Pyridoxamine-d3 dihydrochloride
|
||
Pyridoxamine-d3 dihydrochloride 是 Pyridoxamine dihydrochloride 的氘代化合物。 | |||
TMIH-0039 |
3 Hydroxy Midostaurin Epimer 2-d5
CGP52421 Epimer 2-d5 |
||
3 Hydroxy Midostaurin Epimer 2-d5 是 3 Hydroxy Midostaurin Epimer 2 的氘代化合物。3 Hydroxy Midostaurin Epimer 2 的 CAS 号为 155848-20-7。 | |||
TMIH-0488 |
Reduced Haloperidol-d4
|
||
Reduced Haloperidol-d4 是 Reduced Haloperidol 的氘代化合物。Reduced Haloperidol 的 CAS 号为 34104-67-1。 | |||
TMIH-0404 |
O-Desmethyl Midostaurin-d5
|
||
O-Desmethyl Midostaurin-d5 是 O-Desmethyl Midostaurin 的氘代化合物。 | |||
T73715 |
Risperidone-d4
|
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Risperidone-d4是 Risperidone 的氘代物。Risperidone 是5-HT2受体的阻断剂,P-糖蛋白(P-Glycoprotein)的抑制剂 和dopamine D2受体的拮抗剂,其对 5-HT2A 和 dopamine D2受体的Ki 值分别为 4.8,5.9 nM。 | |||
TMIJ-0459 |
Methamidophos-d6 (dimethyl-d6)
|
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Methamidophos-d6 (dimethyl-d6) 是 Methamidophos 的氘代化合物。 | |||
T19119 |
3-Hydroxy Midostaurin-D5
CGP52421-D5 |
Others | Others |
3-Hydroxy Midostaurin-D5 (CGP52421-D5) is a deuterium-labeled 3-Hydroxy Midostaurin which is a metabolite of PKC412. PKC412 effectively inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation (IC50s: 132 nM and 9.8 μM in culture medium and plasma). | |||
T19407 |
Lurasidone Metabolite 14326 D8
|
Others | Others |
Lurasidone Metabolite 14326 D8 is the deuterium labeled Lurasidone Metabolite 14326. | |||
T11892 |
Lurasidone D8 Hydrochloride
SM-13496 D8 |
Others | Others |
Lurasidone D8 Hydrochloride is an inhibitor of Dopamine D2, 5-HT2A, 5-HT7, 5-HT1A and noradrenaline α2C, and is the deuterium labeled Lurasidone. | |||
T19406 |
Lurasidone Metabolite 14283 D8
|
Others | Others |
Lurasidone Metabolite 14283 D8 is the deuterium labeled Lurasidone Metabolite 14283. | |||
TMIH-0463 |
Pyridoxal-d3
|
||
Pyridoxal-d3 是 Pyridoxal 的氘代化合物。 | |||
T13141 |
Thalidomide D4
|
Others | Others |
Thalidomide D4 is a deuterium labeled Thalidomide, has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties. | |||
TMIH-0464 |
Pyridoxal-d3 Hydrochloride
|
||
Pyridoxal-d3 Hydrochloride 是 Pyridoxal Hydrochloride 的氘代化合物。 | |||
T13400 |
Ziprasidone D8
CP-88059 D8 |
Others | Others |
Ziprasidone D8 is deuterium labeled Ziprasidone, which is a antagonist of combined 5-HT (serotonin) and dopamine receptor and exhibits potent effects of antipsychotic activity. | |||
TMIH-0420 |
Paliperidone-d4
|
||
Paliperidone-d4 是 Paliperidone 的氘代化合物。Paliperidone 的 CAS 号为 144598-75-4。Paliperidone 是 Risperidone 的主要活性代谢产物,是多巴胺 D2 拮抗剂和5-HT2A拮抗剂。它用作非典型抗精神病药,用于精神分裂症的急性及维持治疗。它对α1和α2肾上腺素能受体和H1组胺能受体也有拮抗作用。 | |||
T11535 |
Haloperidol D4
氟哌啶醇D4 |
Others | Others |
Haloperidol D4 is deuterium-labeled haloperidol. | |||
TMIH-0315 |
Lurasidone Inactive Metabolite 14283-d8
5α/6α-Hydroxy Lurasidone-d8 Hydrochloride (Mixture of Diastereomers) |
||
Lurasidone Inactive Metabolite 14283-d8 是 Lurasidone Inactive Metabolite 14283 的氘代化合物。Lurasidone Inactive Metabolite 14283 的 CAS 号为 186204-31-9。 | |||
TMID-0034 |
Haloperidol-d4 TFA
|
||
Haloperidol-d4 TFA 是 Haloperidol TFA 的氘代化合物。 | |||
TMIH-0466 |
Pyridoxine-d3
|
||
Pyridoxine-d3 是 Pyridoxine 的氘代化合物。 | |||
TMIH-0156 |
cis-Clopidogrel-MP-13C-d3 Derivative
|
||
cis-Clopidogrel-MP-13C-d3 Derivative 是 cis-Clopidogrel-MP Derivative 的 13C 和氘代化合物。 | |||
T11536 |
Haloperidol (D4')
Haloperidol D4',氟哌啶醇 (D4') |
Others | Others |
Haloperidol D4' is deuterium-labeled haloperidol. Haloperidol is a dopamine D2 receptor antagonist. | |||
TMIJ-0117 |
rac-Clopidogrel-d4 Hydrogen Sulfate
|
||
rac-Clopidogrel-d4 Hydrogen Sulfate 是 rac-Clopidogrel Hydrogen Sulfate 的氘代化合物。rac-Clopidogrel Hydrogen Sulfate 的 CAS 号为 135046-48-9。(±) Clopidogrel hydrogen sulfate是一种在药理学和结构上类似于ticlopidine的抗血小板药物,用于抑制脑血管疾病、外周血管疾病和冠状动脉疾病等各种疾病中的血栓。 | |||
TMIJ-0228 |
Lidocaine-d6 HCl
|
||
Lidocaine-d6 HCl 是 Lidocaine HCl 的氘代化合物。Lidocaine HCl 的 CAS 号为 73-78-9。Lidocaine hydrochloride 抑制涉及复杂电压和依赖性的钠通道。它通过调节 miR-145 表达和进一步抑制MEK/ERK和NF-κB信号通路来减少胃癌细胞的生长,迁移和侵袭。Lidocaine 是一种酰胺衍生物,是一种研究室性心律失常的药物和有效的肿瘤抑制剂。 | |||
TMID-0228 |
Chlorthalidone-d4
|
||
Chlorthalidone-d4 是 Chlorthalidone 的氘代化合物。Chlorthalidone 的 CAS 号为 77-36-1。Chlorthalidone 是噻嗪类利尿剂,有用于高血压的研究潜力。 | |||
TMIJ-0523 |
Gliquidone-d6
|
||
Gliquidone-d6 是 Gliquidone 的氘代化合物。Gliquidone 的 CAS 号为 33342-05-1。Gliquidone 是一种磺酰脲类的抗糖尿病药物,可用于2型糖尿病的研究。 | |||
TMID-0263 |
Lidocaine-d10 Hydrochloride
|
||
Lidocaine-d10 Hydrochloride 是 Lidocaine Hydrochloride 的氘代化合物。Lidocaine Hydrochloride 的 CAS 号为 73-78-9。Lidocaine hydrochloride 抑制涉及复杂电压和依赖性的钠通道。它通过调节 miR-145 表达和进一步抑制MEK/ERK和NF-κB信号通路来减少胃癌细胞的生长,迁移和侵袭。Lidocaine 是一种酰胺衍生物,是一种研究室性心律失常的药物和有效的肿瘤抑制剂。 | |||
TMID-0200 |
rac-Clopidogrel-d4 Carboxylic Acid
|
||
rac-Clopidogrel-d4 Carboxylic Acid 是 rac-Clopidogrel Carboxylic Acid 的氘代化合物。rac-Clopidogrel Carboxylic Acid 的 CAS 号为 113665-84-2。Clopidogrel 是一种 P2Y12 受体拮抗剂,可降低血小板聚集,用于抑制冠状动脉疾病、周围血管疾病和脑血管疾病中的血凝块。 | |||
TMID-0083 |
Arbidol-d6 Hydrochloride
|
||
Arbidol-d6 Hydrochloride 是 Arbidol Hydrochloride 的氘代化合物。Arbidol Hydrochloride 的 CAS 号为 131707-23-8。Umifenovir hydrochloride 是一种口服有效的广谱抗病毒药物,对多种包膜和非包膜病毒均有活性。它被用作抗流感病毒剂,可通过阻断病毒与宿主细胞膜的融合来抑制包膜病毒的细胞侵袭。它是一种 SARS-CoV-2 抑制剂,具有抗炎活性。 |