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Search Results for " i/r "

Targets Recommended: 5-HT Receptor PKC

44

抑制剂 & 化合物

18

天然产物

1

化合物库

44

重组蛋白

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Cat. No.	Product Name
L4100	TGF-β/Smad靶点化合物库		184 compounds
	184 个 TGF-β/Smad 靶点相关的小分子化合物的特有集合，用于高通量、高内涵筛选；

化合物库

TGF-β/Smad靶点化合物库

Cat.No: L4100

Compounds: 184

Cat. No.	Product Name	Target	Signaling Pathways
T72322	R 59-022 hydrochloride DKGI-I hydrochloride,Diacylglycerol kinase inhibitor I hydrochloride,DKGI-I hydrochloride ; Diacylglycerol kinase inhibitor I hydrochloride	5-HT Receptor; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; GPCR/G Protein; Neuroscience
	R 59-022 hydrochloride (DKGI-I hydrochloride) 是一种 5-HT Receptor 拮抗剂，可激活蛋白激酶 C (PKC)。R 59-022 hydrochloride 是一种 DGK 抑制剂 (IC50:2.8 µM),可抑制 OAG 磷酸化为 OAPA。R 59-022 增强血小板中凝血酶诱导的甘油二酯的产生，并抑制嗜中性粒细胞中磷脂酸的产生。
T12620	(R)-CSN5i-3	Others	Others
	(R)-CSN5i-3 是 R 构型的 CSN5i-3 。
T16709	R 59-022 Diacylglycerol kinase inhibitor I,DKGI-I	Others	Others
	R 59-022 is a 5-HTR antagonist and activates protein kinase C (PKC). R 59-022 is a diacylglycerol kinase inhibitor (IC50=2.8 μM). R 59-022 potentiates thrombin-induced diacylglycerol production in platelets and inhibits phosphatidic acid production in neu
T8476	RSVA405 RSVA 405	AMPK; STAT; Autophagy	Autophagy; Chromatin/Epigenetic; JAK/STAT signaling; PI3K/Akt/mTOR signaling; Stem Cells
	RSVA405 是一种具有口服活性的AMPK 激活剂，EC50值为 1 μM。它也是一种 STAT3 抑制剂，具有抗炎作用，可研究肥胖症。它通过促进 CaMKKβ 依赖的 AMPK 活化，从而抑制mTOR，并促进自噬以增加 Aβ 的降解。
T6547	Ipratropium Bromide Sch 1000,异丙托溴铵,Itrop,Atrovent	AChR	Neuroscience
	Ipratropium Bromide (Sch 1000) 是毒蕈碱的受体的拮抗剂，可用于 COPD 和哮喘等研究，对 M1、M2 和 M3 受体的结合的IC50值分别为 2.9、2 和 1.7 nM。
T19930	Nitrosoglutathione S-Nitrosoglutathione,S-亚硝基谷胱甘肽,SNOG,Glutathione thionitrite,GSNO	RAAS; NO Synthase	Endocrinology/Hormones; Immunology/Inflammation
	Nitrosoglutathione (GSNO) 是一种外源性的 NO 供体，是大鼠酒精脱氢酶III 类同工酶的底物，能够减少脑血管紧张素II 依赖性及非依赖型的 AT1 受体反应。
T0098	Ipratropium bromide monohydrate Ipratropium bromide hydrate,溴化异丙托品单水合物	AChR	Neuroscience
	Ipratropium bromide monohydrate (Ipratropium bromide hydrate) 是一种毒蕈碱拮抗剂，结构上与阿托品相关，但它通常被认为对吸入使用更安全、更有效。它用于各种支气管疾病、鼻炎和抗心律失常。
TD0001	SYBR GREEN 1 SUPER Green I （效果同SYBR Green I）核酸染料（10,000× DMSO溶液）（电泳级）,SYBR(R) GREEN I NUCLEIC ACID GEL STAIN *10,000× concentrate in DMSO,SYBRGREENⅠ核苷酸胶体染料	Others	Others
	SYBR GREEN 1 是一种不对称花青染料，用于检测核酸。它由一个 N-烷基化的苯并噻唑或苯并恶唑环系统组成，通过一甲基桥连接到吡啶鎓或喹啉鎓环系统。 SYBR Green I 与 dsDNA 的小沟结合，在 480 nm 波长处被激发。它具有 520 nm 的峰值荧光发射。
T29061	UNC0006 UNC-0006,UNC 0006	cAMP	GPCR/G Protein
	UNC0006 是 β抑制蛋白偏向 D（2）R 配体，同时也是 G（i）调节的 cAMP 产生的拮抗剂和 D（2）R/β-arrestin-2 相互作用的部分激动剂。UNC0006 具有抗精神病的活性，可用于研究神经系统疾病。
T16708	R-268712	ALK; TGF-beta/Smad	Angiogenesis; Stem Cells; Tyrosine Kinase/Adaptors
	R-268712 是选择性的 ALK5 抑制剂(IC50:2.5 nM)。
T27335	Floctafenine RU 15750,R-4318,R 4318,RU-15750,R4318	COX	Immunology/Inflammation; Neuroscience
	Floctafenine (R-4318) 是一种可口服的非甾体抗炎化合物，是 COX-I 和 COX-2 抑制剂，可干扰阿司匹林的抗血小板作用。Floctafenine 具有镇痛活性，可用于研究疼痛。
T4191	Multi-kinase inhibitor 1 Multi-kinase inhibitor I	Others; Bcr-Abl; PDGFR; c-Kit	Angiogenesis; Cytoskeletal Signaling; Others; Tyrosine Kinase/Adaptors
	Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) 是多激酶抑制剂。它有用于导致与酪氨酸激酶活性异常或失控有关的疾病或失调的潜力，特别是与c-Kit，PDGF-R，Bcr-abl 活性相关的疾病。
T30981	Clometocillin Penicilline 356	Others	Others
	Clometocillin is a penicillin that can active penicillin to pen-I or pen-R pneumococci.
T15672	KU14R	Others	Others
	KU14R is a new I(3)-R antagonist, which selectively blocks the insulin secretory response to imidazolines.
T33451	ML 7 ML7,ML-7	Others	Others
	ML 7 is an inhibitor of myosin light chain kinase that protects cardiac function from ischemia/reperfusion (I/R) injury.
T61491	(R)-ND-336	Others	Others
	(R)-ND-336 is a highly potent and selective MMP-9 inhibitor, displaying a K i value of 19 nM. It also exhibits inhibitory activity against MMP-2 (K i = 127 nM) and MMP-14 (K i =119 nM). With its significant potential, (R)-ND-336 is being investigated in the field of diabetic foot ulcers (DFUs) research [1].
T61980	Carbonic anhydrase inhibitor 8	Others	Others
	Carbonic anhydrase inhibitor 8 (compound R-13) 是一种有效的人碳酸酐酶 (hCA) 抑制剂。Carbonic anhydrase inhibitor 8抑制 hCA I、hCA II、hCA IV 的Ki 值分别为 60.7 nM、320.7 nM、2298 nM。
T39870	5-HT7R antagonist 1 free base 5-HT7R antagonist 1 free base	Others	Others
	5-HT7R antagonist 1 (free base) is a G protein-biased antagonist for the 5-HT 7 R receptor, with a dissociation constant (K i) of 6.5 nM.
T39795	Tricarbonyldichlororuthenium(II) dimer CORM-2	Others	Others
	Tricarbonyldichlororuthenium(II) dimer, a pharmacological CO donor, prevents ischemia/reperfusion (I/R)-induced oxidative damage to the gastric mucosa by enhancing gastric blood flow (GBF) and reducing DNA oxidation and systemic inflammatory response.
T74723	MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan	Others; Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related; Others
	MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan 是一种抗体偶联活性分子的一部分 (drug-linker conjugate for ADC)，包含 Exatecan 。Exatecan 是一种 DNA 拓扑异构酶 I (Topoisomerase I) 抑制剂 (IC50=2.2 μM)。
T22140	(R)-SLV 319	Others	Others
	(R)-SLV 319 是一种有效的、选择性的大麻素受体 1 (CB1)拮抗剂，Ki 值为 894 nM。(R)-SLV 319 是 SLV 319 的右旋对映体。
T84597	(R)-Palmitoyl-(2-methyl)ethanolamide Me-PEA	Others	Others
	(R)-Palmitoyl-(2-methyl)ethanolamide (Me-PEA)是具有6.6μM Ki值的[3H]-AEA代谢的竞争性抑制剂。
T61982	Human carbonic anhydrase II-IN-2	Others	Others
	Human carbonic anhydrase II-IN-24 (Compound R-13) 是一种有效的人碳酸酐酶(hCA)抑制剂。Human carbonic anhydrase II-IN-24抑制 hCA I、II、IV 和 IX 的 Ki 分别为 60.7、320.7 和 2298 和 35.2 nM。
T71001	GSK-598809	Others	Others
	GSK598809 is a selective D(3)R antagonist recently progressed in Phase I trials. GSK-598809 may decrease the rewarding effects of contextual cues associated with drug intake preclinically, which may reduce drug craving in humans.
T37680	3-hydroxy Palmitic Acid methyl ester	Others	Others
	3-hydroxy Palmitic acid methyl ester (3-hydroxy PAME) is an esterized long-chain fatty acid involved in quorum sensing in R. solanacearum, a bacteria that causes lethal wilting in plants. 3-hydroxy-PAME (175 nM) increases levels of PhcA-regulated virulence factors, greater than 20-, 30-, and 25-fold for EPS I, EGL, and PME, respectively, in the AW1-83 strain of R. solanacearum.
T74331	hCAII-IN-7	Others	Others
	hCAII-IN-7 (Compound R-13) 是一种有效的人碳酸酐酶(hCA)抑制剂，对 hCA I、II、IV 和 IX 的 Ki 分别为 60.7、320.7 和 2298 和 35.2 nM。
T83043	Anti-MI/R injury agent 1	Others	Others
	Anti-MI/R injury agent 1 (compound 18) 是一种口服有效的人参三醇衍生物，专用于抗心肌缺血/再灌注 (MI/R) 损伤。该化合物能增强经氧-葡萄糖剥夺和再灌注 (OGD/R) 诱导心肌细胞损伤模型中的细胞活力，显着缩小大鼠心肌梗死面积，减少循环心肌肌钙蛋白 I (cTnI) 的释放，并减轻心脏组织损害。
T81267	RIPK3-IN-4	RIP kinase	Apoptosis; NF-κB
	RIPK3-IN-4（Compound 42）是一种抑制RIPK3活性的化合物。它能有效减轻HK-2细胞的损伤和凋亡（necroptosis），同时降低急性肾损伤中（Cisplatin）以及缺血/再灌注（I/R）引起的肾脏损伤、炎症及坏死性凋亡现象。
T74724	MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan	Others; Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related; Others
	MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan 是抗体偶联活性分子的一部分 (drug-linker conjugate for ADC)，包含 Exatecan 。Exatecan 是一种 DNA 拓扑异构酶 I (Topoisomerase I) 抑制剂 (IC50=2.2 μM)。
T76223	NH2-c[X-R-L-S-X]-K-G-P-(D-1Nal)	Others	Others
	NH2-c[X-R-L-S-X]-K-G-P-(D-1Nal) (化合物 39) 作为APJ激动剂表现出高亲和力，其Ki值为0.6 nM。该化合物能有效激活Gαi1，具有EC50值0.8 nM，并能募集β-arrestin2，相关EC50值为31 nM。同时，NH2-c[X-R-L-S-X]-K-G-P-(D-1Nal) 对心脏功能具有显著的延长作用。
T80138	(D-Arg8)-Inotocin	Vasopressin Receptor	GPCR/G Protein
	"(D-Arg8)-Inotocin"是一种对加压素受体V1aR表现出高效、选择性和竞争性拮抗作用的化合物，其Ki值为1.3 nM。该化合物对人类V1aR具有显著的选择性，相较于其他三种亚型(OTR, V1bR, V2R)，其选择性超过3000倍。
T38329	CU-76	Others	Others
	CU-76 is an inhibitor of cyclic GMP-AMP synthase (cGAS; IC50= 0.24 μM).1It reduces DNA-, but not Sendai virus-, induced dimerization of IFN regulatory factor 3 in THP-1 cells, indicating selectivity for the cGAS DNA sensing pathway over the RIG-I-MAVS RNA sensing pathway. CU-76 decreases IFN-stimulatory DNA-induced production of IFN-β in THP-1 cells when used at concentrations of 10, 30, and 100 μM. 1.Padilla-Salinas, R., Sun, L., Anderson, R., et al.Discovery of small-molecule cyclic GMP-AMP sy...
T37887	1-Heptadecanoyl-rac-glycerol	Others	Others
	1-Heptadecanoyl-rac-glycerol is a monoacylglycerol that contains heptadecanoic acid at the sn-1 position. It is active against the bacteria E. aerogens, E. cloacae, P. mirabilis, and S. faecalis (MIC = 78 μg/ml for all).1 1-Heptadecanoyl-rac-glycerol has been found in T. africana, I. sonorae, and wheat bran.1,2,3 \|1. Kuete, V., Metuno, R., Ngameni, B., et al. Antimicrobial activity of the methanolic extracts and compounds from Treculia africana and Treculia acuminata (Moraceae). S. Afr. J. Bot. ...
T38328	CU-32	Others	Others
	CU-32 is an inhibitor of cyclic GMP-AMP (cGAMP) synthase (cGAS; IC50= 0.45 μM).1It reduces DNA-, but not Sendai virus-, induced dimerization of IFN regulatory factor 3 in THP-1 cells, indicating selectivity for the cGAS DNA sensing pathway over the RIG-I-MAVS RNA sensing pathway. It is also selective for cGAS over toll-like receptors (TLRs) at 50 μM. CU-32 decreases IFN-stimulatory DNA-induced production of IFN-β in THP-1 cells when used at concentrations of 10, 30, and 100 μM. 1.Padilla-Salinas...
T72091	ADRA1D receptor antagonist 1 free base	Others	Others
	ADRA1D receptor antagonist 1 (free base) (化合物 (R)-9s)，是口服高效、强效及选择性的人类α1D-肾上腺素受体（α1D-AR）拮抗剂，具有Ki值为1.6 nM。该化合物能剂量依赖性降低膀胱收缩，IC30值为15 nM，适用于膀胱过度活动症（包括尿急、尿频和尿失禁）的研究。
T35762	MC1742	Others	Others
	MC1742 is an inhibitor of class I histone deacetylases (HDACs; IC50s = 0.1, 0.11, 0.02, and 0.61 μM for HDAC1, -2, -3, and -8, respectively) and class IIb HDACs (IC50s = 7 and 40 nM for HDAC6 and HDAC10, respectively).1 It is selective for class I and class IIb over class IIa HDACs (IC50s = >50 μM for HDAC4, -5, -7, and -9). MC1742 reduces proliferation of HOS, MG-63, RD, A204, SK-ES-1, and A673 sarcoma cancer stem cells (CSCs). It increases levels of acetylated histone H3 and acetylated tubulin...
T37536	Carbazomycin A	Others	Others
	Carbazomycin A is a bacterial metabolite that has been found in Streptomyces and has diverse biological activities.1,2It is active againstS. aureus,T. asteroides, andT. mentagrophytes(MIC = 12.5 μg/ml for all), as well as the plant pathogenic fungusP. oryzae(MIC = 25 μg/ml). Carbazomycin A is cytotoxic to MCF-7, KB, NCI H187, and Vero cells (IC50s = 26.2, 30.1, 18.4, and 32.6 μg/ml, respectively).2 1.Sakano, K.-I., Ishimaru, K., and Nakamura, S.New antibiotics, carbazomycins A and B. I. Fermenta...
T36929	Pal-KTTKS (acetate)	Others	Others
	Pal-KTTKS is a lipidated pentapeptide consisting of a fragment of the type I collagen C-terminal propeptide conjugated to palmitic acid .1 It increases collagen production in human corneal and dermal fibroblasts when used at concentrations of 0.002, 0.004, and 0.008 wt%.2 Following topical administration, pal-KTTKS (50 μg/cm2) is found in the stratum corneum, epidermis, and dermis of isolated hairless mouse skin.1 It can self-assemble into flat tapes and extended fibrillar structures.3 Pal-KTTKS...
T36679	Rp-cAMPS sodium salt	Others	Others
	Rp-cAMPS sodium salt, a cAMP analog, is a potent, competitive cAMP-induced activation of cAMP-dependent PKA I and II (Kis of 12.5 μM and 4.5 μM, respectively) antagonist. Rp-cAMPS sodium salt is resistant to hydrolysis by phosphodiesterases[1][2][3][4][5][6]. A membrane-permeable competitive cAMP antagonist (Rp-cAMPS) that blocks PKA activation by binding to the regulatory subunits without dissociating the kinase holoenzyme also inhibits synaptic plasticity but has no effect on normal synaptic t...
T38284	C24 dihydro 1-Deoxyceramide (m18:0/24:0) C24 dihydro 1-Deoxyceramide (m18:0/24:0)	Others	Others
	C24 dihydro 1-Deoxyceramide (m18:0/24:0) is a very long-chain atypical ceramide containing a 1-deoxysphinganine backbone. 1-Deoxysphingolipids are formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.1,2 C24 dihydro 1-Deoxyceramide (m18:0/24:0) has been found in mouse embryonic fibroblasts (MEFs) following application of 1-deoxysphinganine alkyne or 1-deoxysphinganine-d3.3 It has also been found in mouse brain, spinal cord, ...
T38280	C22 dihydro 1-Deoxyceramide (m18:0/22:0) C22 dihydro 1-Deoxyceramide (m18:0/22:0)	Others	Others
	C22 dihydro 1-Deoxyceramide (m18:0/22:0) is a very long-chain atypical ceramide containing a 1-deoxysphinganine backbone. 1-Deoxysphingolipids are formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.1,2 C22 dihydro 1-Deoxyceramide (m18:0/22:0) has been found in mouse embryonic fibroblasts (MEFs) following application of 1-deoxysphinganine alkyne or 1-deoxysphinganine-d3.3 It has also been found as the most prevalent dihydro...
T83765	Dendrogenin A DDA	Others	Others
	Dendrogenin A (DDA) 作为一种选择性肝X受体(LXR)调节剂(SLiM)、胆固醇环氧水解酶(ChEH; Ki = 120 nM)的抑制剂及胆固醇的活性代谢产物，通过DDA合成酶将5,6α-环氧胆固醇与组胺结合形成。DDA在非癌性人乳腺上皮细胞和上皮黑色素细胞中存在，但在多种乳腺癌细胞或黑色素瘤细胞中未发现，且在分离的人乳腺肿瘤组织中仅以低水平存在。它抑制22(R)-羟基胆固醇诱导的LXRβ和LXRα激活(分别以IC50 = 76和362 nM)，但也是LXR的部分激动剂，在B16/F10小鼠黑色素瘤细胞中增加Nur77、NOR-1、LC3-I和LC3-II的蛋白水平。DDA选择性调节LXRα和LXRβ，而非孕烯X受体(PXR)、芳香烃受体(AhR)、维生素D受体(VDR)、维甲酸X受体γ(RXRγ)、维甲酸受体α(RARα)、过氧化物酶体增殖物激活受体α(PPARα)、PPARγ、糖皮质激素受体、雄激素受体、雌激素受体α(ERα)及ERβ在2.5 µM下。此外，DDA在2.5和5 µM的浓度下增加B16/F10和SK-MEL-28癌细胞中LC3-II的蛋白水平，并在2...
T38214	1-Deoxysphingosine (m18:1(4E)) 1-Deoxysphingosine (m18:1(4E))	Others	Others
	1-Deoxysphingosine (m18:1(4E)) is an atypical sphingolipid that contains a double bond at the 4E native position and is formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.1,2 Plasma levels of 1-deoxysphingosine (m18:1(4E)) are increased in patients with chronic idiopathic axonal neuropathy (CIAP) and diabetic distal symmetrical polyneuropathy (DSPN).3 \|1. Steiner, R., Saied, E.M., Othman, A., et al. Elucidating the chemica...
T36892	4'-Acetyl Chrysomycin A	Others	Others
	4'-Acetyl chrysomycin A is a bacterial metabolite and derivative of chrysomycin A that has been found inStreptomycesand has antibacterial and anticancer activities.1It is active against strains of methicillin-resistantS. aureus(MRSA) and vancomycin-resistant strains ofE. faecalisandE. faecium(MICs = 0.5-2 μg/ml for all). 4'-Acetyl chrysomycin A is cytotoxic against a panel of human cancer cell lines, including doxorubicin-sensitive or -resistant cells (IC50s = 0.085-0.26 and 3.4-16 ng/ml, respec...

化合物

R 59-022 hydrochloride

Cat.No: T72322

Synonym: DKGI-I hydrochloride,Diacylglycerol kinase inhibitor I hydrochloride,DKGI-I hydrochloride ; Diacylglycerol kinase inhibitor I hydrochloride

Target: 5-HT Receptor, PKC

Cat.No: T12620

Target: Others

Cat.No: T16709

Synonym: Diacylglycerol kinase inhibitor I,DKGI-I

Target: Others

Cat.No: T8476

Synonym: RSVA 405

Target: AMPK, STAT, Autophagy

Ipratropium Bromide

Cat.No: T6547

Synonym: Sch 1000,异丙托溴铵,Itrop,Atrovent

Target: AChR

Nitrosoglutathione

Cat.No: T19930

Synonym: S-Nitrosoglutathione,S-亚硝基谷胱甘肽,SNOG,Glutathione thionitrite,GSNO

Target: RAAS, NO Synthase

Ipratropium bromide monohydrate

Cat.No: T0098

Synonym: Ipratropium bromide hydrate,溴化异丙托品单水合物

Target: AChR

Cat.No: TD0001

Synonym: SUPER Green I （效果同SYBR Green I）核酸染料（10,000× DMSO溶液）（电泳级）,SYBR(R) GREEN I NUCLEIC ACID GEL STAIN *10,000× concentrate in DMSO,SYBRGREENⅠ核苷酸胶体染料

Target: Others

Cat.No: T29061

Synonym: UNC-0006,UNC 0006

Target: cAMP

Cat.No: T16708

Target: ALK, TGF-beta/Smad

Cat.No: T27335

Synonym: RU 15750,R-4318,R 4318,RU-15750,R4318

Target: COX

Multi-kinase inhibitor 1

Cat.No: T4191

Synonym: Multi-kinase inhibitor I

Target: Others, Bcr-Abl, PDGFR, c-Kit

Cat.No: T30981

Synonym: Penicilline 356

Target: Others

Cat.No: T15672

Target: Others

Cat.No: T33451

Synonym: ML7,ML-7

Target: Others

Cat.No: T61491

Target: Others

Carbonic anhydrase inhibitor 8

Cat.No: T61980

Target: Others

5-HT7R antagonist 1 free base

Cat.No: T39870

Synonym: 5-HT7R antagonist 1 free base

Target: Others

Tricarbonyldichlororuthenium(II) dimer

Cat.No: T39795

Synonym: CORM-2

Target: Others

MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan

Cat.No: T74723

Target: Others, Drug-Linker Conjugates for ADC

Cat.No: T22140

Target: Others

(R)-Palmitoyl-(2-methyl)ethanolamide

Cat.No: T84597

Synonym: Me-PEA

Target: Others

Human carbonic anhydrase II-IN-2

Cat.No: T61982

Target: Others

Cat.No: T71001

Target: Others

3-hydroxy Palmitic Acid methyl ester

Cat.No: T37680

Target: Others

Cat.No: T74331

Target: Others

Anti-MI/R injury agent 1

Cat.No: T83043

Target: Others

Cat.No: T81267

Target: RIP kinase

MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan

Cat.No: T74724

Target: Others, Drug-Linker Conjugates for ADC

NH2-c[X-R-L-S-X]-K-G-P-(D-1Nal)

Cat.No: T76223

Target: Others

(D-Arg8)-Inotocin

Cat.No: T80138

Target: Vasopressin Receptor

Cat.No: T38329

Target: Others

1-Heptadecanoyl-rac-glycerol

Cat.No: T37887

Target: Others

Cat.No: T38328

Target: Others

ADRA1D receptor antagonist 1 free base

Cat.No: T72091

Target: Others

Cat.No: T35762

Target: Others

Cat.No: T37536

Target: Others

Pal-KTTKS (acetate)

Cat.No: T36929

Target: Others

Rp-cAMPS sodium salt

Cat.No: T36679

Target: Others

C24 dihydro 1-Deoxyceramide (m18:0/24:0)

Cat.No: T38284

Synonym: C24 dihydro 1-Deoxyceramide (m18:0/24:0)

Target: Others

C22 dihydro 1-Deoxyceramide (m18:0/22:0)

Cat.No: T38280

Synonym: C22 dihydro 1-Deoxyceramide (m18:0/22:0)

Target: Others

Cat.No: T83765

Synonym: DDA

Target: Others

1-Deoxysphingosine (m18:1(4E))

Cat.No: T38214

Synonym: 1-Deoxysphingosine (m18:1(4E))

Target: Others

4'-Acetyl Chrysomycin A

Cat.No: T36892

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TN1895	Luteolinidin chloride	CD38	Immunology/Inflammation
	Luteolinidin chloride 是天然的脱氧花青素，分离自苔藓和蕨类植物中。它是一种有效的 CD38 抑制剂，可以保留 eNOS 功能并预防体内内皮功能障碍，同时可以保护心脏免受 I/R 损伤。
T2961	Notoginsenoside R1 Sanqi glucoside R1,Sanchinoside R1,三七皂苷R1	Apoptosis; ERK; Beta Amyloid	Apoptosis; MAPK; Neuroscience
	Notoginsenoside R1 (Sanchinoside R1) 属于皂苷类天然产物，是三七的主要活性单体。Notoginsenoside R1 具有心血管保护、神经保护、肝脏保护、抗肿瘤、免疫调节等活性。
T21328	Carubicin carminomycin,Carminomycin I,Carminomicin I,Antibiotic R 588A,Demethyldaunomycin	Others	Others
	Carubicin is an anthracycline antineoplastic antibiotic isolated from the bacterium Actinomadura carminata. Carubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis.
TN5997	Stipuleanoside R1 Tarasaponin I,屏边三七苷R1
	Stipuleanoside R1 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5997，CAS号为 96627-79-1。
T5S1262	Methylophiopogonanone A	Others	Others
	Methylophiopogonanone A 是从Ophiopogon japonicas 提取到的黄酮类化合物，具有抗炎和抗氧化的特性。它通过调节 MMP-9 和紧密连接蛋白的表达来减轻 BBB 破坏的能力，具有治疗脑 I/R 损伤的潜力。
T5S1632	Barlerin 8-O-乙酰山栀苷甲酯,8-O-Acetylshanzhiside methyl ester,ND01	VEGFR; TNF; NF-κB; Akt; Caspase	Angiogenesis; Apoptosis; Cytoskeletal Signaling; NF-κB; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Tyrosine Kinase/Adaptors
	Barlerin (8-O-Acetylshanzhiside methyl ester) 是一种环孢菌素葡萄糖苷，从中国西藏民间药用植物中分离得到，能够抑制NF-κB 活性。
T3753	Sinapinic Acid Sinapic acid,芥子酸,Synapoic acid	Apoptosis; RAAS; Reactive Oxygen Species; HDAC	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Endocrinology/Hormones; Immunology/Inflammation; Metabolism; NF-κB
	Sinapinic Acid (Synapoic acid) 是从 Hydnophytum formicarumJack. 根中分离到的酚类，是HDAC 抑制剂，对ACE-I 的活性也有抑制作用。它有抗肿瘤活性，诱导肿瘤细胞凋亡，具有抗氧化、抗糖尿病的作用。
T6S1369	Vitexin 牡荆素,Apigenin-8-C-glucoside	Antioxidant	oxidation-reduction
	Vitexin 是一种存在于多种药用植物（如榕树、螺旋藻）中的 c-糖基化的黄酮。它具有广泛的药理作用，包括抗氧化，抗癌，抗炎，抗痛觉过敏和神经保护作用。
T3893	Forsythoside B 连翘酯苷 B,连翘脂苷B	TNF; NF-κB	Apoptosis; NF-κB
	Forsythoside B 是传统中药植物独一味叶子中分离的一种苯乙醇苷。它可抑制 TNF-alpha，IL-6，IκB，调节 NF-κB。它抑制炎症反应，具有抗氧化和神经保护作用。
T5S0053	Coptisine 黄连碱,Coptisin	Indoleamine 2,3-Dioxygenase (IDO)	Metabolism
	Coptisine (Coptisin) 是一种从黄连中分离到的生物碱，是非竞争性的IDO 抑制剂，Ki=为 5.8 μM，IC50=6.3 μM。
T13576	β-cyano-L-Alanine Beta-cyano-l-alanine	Others	Others
	β-cyano-L-Alanine (Beta-cyano-l-alanine) 是广泛存在于高等植物中的腈，氰基丙氨酸合成酶以氰化物和半胱氨酸作为底物反应产生。它消除了乙醇对脑缺血/再灌注 (I/R) 损伤的保护作用。
T4S2326	Cornuside 7-Galloylsecologanol,7-O-Galloylsecologanol,山茱萸新苷,Comuside	ERK; p38 MAPK; NF-κB; JNK	MAPK; NF-κB
	Cornuside (Comuside) 是从山茱萸的果实中分离出的环烯醚萜苷，可用于炎症疾病的研究和促进血液循环。它通过下调 MAPK 和 NF-κB 信号通路抑制肥大细胞介导的过敏反应，用于炎性过敏性疾病中的潜能。
T3895	Polyphyllin I 重楼皂苷I,重楼皂甙	Apoptosis; Akt; JNK; PDK; mTOR; Autophagy	Apoptosis; Autophagy; Cytoskeletal Signaling; MAPK; PI3K/Akt/mTOR signaling
	Polyphyllin I 是从七叶一枝花中提取的生物活性成分，具有很强的抗肿瘤活性。它是 JNK 信号通路的激活剂，也是 PDK1/Akt/mTOR 信号传导的抑制剂。它诱导自噬，G2/M 期阻滞和细胞凋亡。
T40576	(S)-Salsolidine	Others	Others
	(S)-Salsolidine, a chemical compound, functions as a weak inhibitor of monoamine oxidase (MAO), exhibiting an inhibition constant (K i ) of 63 μM. R enantiomer demonstrating a greater efficacy than (S)-Salsolidine, boasting a K i value of 26 μM compared to the S form.
TN3914	Echinatine	ATPase; IL Receptor; TNF	Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel
	Echinatin exerts a protective effect against ischemia/reperfusion (I/R)-induced myocardial injury on hearts, this effect may be attributed to the antioxidant and anti-inflammatory activities of this compound. Echinatin can inhibit DNP-ATPase activity whil
TN7266	Harzianopyridone (-)-Harzianopyridone	Others	Others
	Harzianopyridone is an atpenin-like compound that functions as an inhibitor of mammalian and nematode mitochondrial complex II, also known as succinate:ubiquinone oxidoreductase (SQR), demonstrating IC50 values of 0.017, 0.2, and 2 μM against bovine, rat, and nematode complex II, respectively. Additionally, it inhibits nematode quinol-fumarate reductase (QFR) with an IC50 value of 0.36 μM. Significantly selective for complex II over complexes I and III in rats and cattle, as well as complex I in...
T19169	9-cis-Retinal	Others	Others
	9-cis-Retinal is a natural retinoid. Dietary 9-cis-β-carotene generates 9-cis-retinoids via cleavage into 9-cis-retinal. 9-cis Retinal binds to CRBP-I and CRBP-II (Kds: 8 nM and 5 nM). It expedites differentiation and maturation of rod photoreceptors in r
T36000	3-Hydroxyterphenyllin	Others	Others
	3-Hydroxyterphenyllin is a p-terphenyl fungal metabolite originally isolated from A. candidus that has diverse biological activities, including antioxidant, antiproliferative, antibacterial, and antiviral properties.1,2,3,4 It has a 96% scavenging effect on 2,2-diphenyl-1-picrylhydrazyl radicals when used at a concentration of 100 μg/ml.2 3-Hydroxyterphenyllin inhibits the growth of HeLa cervical, A549 lung, and HepG2 liver cancer cells (IC50s = 23, 36, and 32 μM, respectively), as well as methi...

天然产物

Luteolinidin chloride

Cat.No: TN1895

Target: CD38

Notoginsenoside R1

Cat.No: T2961

Synonym: Sanqi glucoside R1,Sanchinoside R1,三七皂苷R1

Target: Apoptosis, ERK, Beta Amyloid

Cat.No: T21328

Synonym: carminomycin,Carminomycin I,Carminomicin I,Antibiotic R 588A,Demethyldaunomycin

Target: Others

Stipuleanoside R1

Cat.No: TN5997

Synonym: Tarasaponin I,屏边三七苷R1

Methylophiopogonanone A

Cat.No: T5S1262

Target: Others

Cat.No: T5S1632

Synonym: 8-O-乙酰山栀苷甲酯,8-O-Acetylshanzhiside methyl ester,ND01

Target: VEGFR, TNF, NF-κB, Akt, Caspase

Cat.No: T3753

Synonym: Sinapic acid,芥子酸,Synapoic acid

Target: Apoptosis, RAAS, Reactive Oxygen Species, HDAC

Cat.No: T6S1369

Synonym: 牡荆素,Apigenin-8-C-glucoside

Target: Antioxidant

Cat.No: T3893

Synonym: 连翘酯苷 B,连翘脂苷B

Target: TNF, NF-κB

Cat.No: T5S0053

Synonym: 黄连碱,Coptisin

Target: Indoleamine 2,3-Dioxygenase (IDO)

β-cyano-L-Alanine

Cat.No: T13576

Synonym: Beta-cyano-l-alanine

Target: Others

Cat.No: T4S2326

Synonym: 7-Galloylsecologanol,7-O-Galloylsecologanol,山茱萸新苷,Comuside

Target: ERK, p38 MAPK, NF-κB, JNK

Cat.No: T3895

Synonym: 重楼皂苷I,重楼皂甙

Target: Apoptosis, Akt, JNK, PDK, mTOR, Autophagy

(S)-Salsolidine

Cat.No: T40576

Target: Others

Cat.No: TN3914

Target: ATPase, IL Receptor, TNF

Harzianopyridone

Cat.No: TN7266

Synonym: (-)-Harzianopyridone

Target: Others

Cat.No: T19169

Target: Others

3-Hydroxyterphenyllin

Cat.No: T36000

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00834	IGF1R/CD221 Protein, Human, Recombinant (His) IGF-I R,IGFR,	Human	HEK293 Cells
	IGF1R/CD221 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 81 kDa and the accession number is P08069.
TMPY-01459	TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His) p60,TNFR60,TNFAR,TBP1,CD120a,TNFR...	Human	HEK293 Cells
	TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.7 kDa and the accession number is P19438-1.
TMPY-02535	TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (hFc) TNFalpha-R1,TNFAR,TNF-R-I	Mouse	HEK293 Cells
	TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.4 kDa and the accession number is P25118.
TMPJ-01464	IL-2 Superkine Protein, Human, Recombinant (L100F, R101D, L105V, I106V, I112F) TCGF,Aldesleukin,T-Cell Growth Factor<...	Human	HEK293 Cells
	Interleukin-2(IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system，belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages...
TMPH-02215	TCN1 Protein, Human, Recombinant (His) TCN1,Haptocorrin,Transco...	Human	P. pastoris (Yeast)
	Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach.
TMPH-02216	TCN1 Protein, Human, Recombinant (His & SUMO) Transcobalamin-1,Haptocorr	Human	E. coli
	Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach.
TMPK-00456	IGF1R/CD221 Protein, Human, Recombinant (aa 31-932, His & Avi), Biotinylated CD221,MGC142172,IGFIR,IG...	Human	HEK293 Cells
	The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection. IGF signalling also influences hypoxia signalling, protease secretion, tumour cell motility and adhesion, and thus can affect the propensity for invasion and metastasis. Therefore, the IGF1R is now an attractive anti-cancer treatment target. IGF1R/CD221 Protein, Human, Recombinant (aa 31-932, His & Avi), Biotinylated is expressed in ...
TMPK-00658	IGF1R/CD221 Protein, Cynomolgus, Recombinant (His) CD221,IGFR,IGF1R,MGC1421...	Cynomolgus	HEK293 Cells
	The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection. IGF signalling also influences hypoxia signalling, protease secretion, tumour cell motility and adhesion, and thus can affect the propensity for invasion and metastasis. Therefore, the IGF1R is now an attractive anti-cancer treatment target. IGF1R/CD221 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells wit...
TMPK-00455	IGF1R/CD221 Protein, Human, Recombinant (His & Avi) MGC142172,IGF-I receptor...	Human	HEK293 Cells
	The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection. IGF signalling also influences hypoxia signalling, protease secretion, tumour cell motility and adhesion, and thus can affect the propensity for invasion and metastasis. Therefore, the IGF1R is now an attractive anti-cancer treatment target. IGF1R/CD221 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells wi...
TMPY-06905	IGF1R/CD221 Protein, Human, Recombinant (His & Avi), Biotinylated CD221,insulin-like growt...	Human	HEK293 Cells
	IGF1R/CD221 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 106.14 kDa and the accession number is NP_000866.1.
TMPY-04360	IGF1R/CD221 Protein, Human, Recombinant (His & GST) JTK13,insulin-like growt...	Human	Baculovirus Insect Cells
	IGF1R/CD221 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 74.6 kDa and the accession number is P08069.
TMPY-01639	TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (His) TNFalpha-R1,TNFRp55,CD120a,TNF-alphaR<...	Mouse	HEK293 Cells
	TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.8 kDa and the accession number is P25118.
TMPY-05475	TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (hFc) MS5,p55-R,p60,TNFR1-d2,TNFR55,TNF...	Human	HEK293 Cells
	TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48 kDa and the accession number is P19438-1.
TMPY-01618	GLO1 Protein, Mouse, Recombinant (His) glyoxalase I,Glo-1r,GLY1,Glo1-r,2...	Mouse	E. coli
	Lactoylglutathione lyase, also known as Methylglyoxalase, Aldoketomutase, Glyoxalase I, Ketone-aldehyde mutase, S-D-lactoylglutathione methylglyoxal lyase and GLO1, is a member of the glyoxalase I family. GLO1 / Glyoxalase I is a ubiquitous cellular defense enzyme involved in the detoxification of methylglyoxal, a cytotoxic byproduct of glycolysis. Accumulative evidence suggests an important role of GLO1 expression in protection against methylglyoxal-dependent protein adduction and cellul...
TMPY-05045	CSF1R Protein, Human, Recombinant (Domain I&II&III, His) M-CSF-R,colony stimulating facto<...	Human	HEK293 Cells
	CSF1R Protein, Human, Recombinant (Domain I&II&III, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.1 kDa and the accession number is P07333-1.
TMPY-05958	SARS-CoV-2 Spike RBD Protein (R408I, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike RBD Protein (R408I, His) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.5 kDa and the accession number is A0A6G7K2L4.
TMPY-06202	SARS-CoV-2 Nucleocapsid Protein (A119S & R203K & G204R & M234I, His)	SARS-CoV-2	E. coli
	SARS-CoV-2 Nucleocapsid Protein (A119S & R203K & G204R & M234I, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 46.7 kDa and the accession number is P0DTC9.
TMPY-06422	SARS-CoV-2 Spike S1 NTD Protein (T19R & T95I & G142D & 156-157 deletion & R158G, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike S1 NTD Protein (T19R & T95I & G142D & 156-157 deletion & R158G, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.10 kDa and the accession number is A0A6G7K2L4.
TMPY-06444	SARS-CoV-2 Spike S1 Protein (T19R & T95I & E156G & 157-158 deletion & L452R & T478K & D614G & P681R, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike S1 Protein (T19R & T95I & E156G & 157-158 deletion & L452R & T478K & D614G & P681R, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.23 kDa and the accession number is YP_009724390.1.
TMPY-06251	SARS-CoV-2 Spike S1 Protein (T95I & G142D & E154K & L452R & E484Q & D614G & P681R, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike S1 Protein (T95I & G142D & E154K & L452R & E484Q & D614G & P681R, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.58 kDa and the accession number is A0A6G7K2L4.
TMPY-06293	SARS-CoV-2 Spike S1 Protein (T95I & G142D & E154K & L452R & E484Q & D614G & P681R, His & Avi), Biotinylated	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike S1 Protein (T95I & G142D & E154K & L452R & E484Q & D614G & P681R, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 78.39 kDa and the accession number is A0A6G7K2L4.
TMPY-06443	SARS-CoV-2 Spike S1 Protein (T19R & T95I & G142D & Y145H & E156G & 157-158 deletion & A222V & L452R & T478K & D614G & P681R, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike S1 Protein (T19R & T95I & G142D & Y145H & E156G & 157-158 deletion & A222V & L452R & T478K & D614G & P681R, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.29 kDa and the accession number is YP_009724390.1.
TMPY-06122	SARS-CoV-2 Spike S1 NTD Protein (L18F & D80A & D215G & LAL242-244 deletion & R246I, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike S1 NTD Protein (L18F & D80A & D215G & LAL242-244 deletion & R246I, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.9 kDa and the accession number is A0A6G7K2L4.
TMPY-06271	SARS-CoV-2 Spike S1+S2 Protein (T95I & G142D & E154K & L452R & E484Q & D614G & P681R & Q1071H, His)	SARS-CoV-2	Baculovirus Insect Cells
	SARS-CoV-2 Spike S1+S2 Protein (T95I & G142D & E154K & L452R & E484Q & D614G & P681R & Q1071H, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 134.51 kDa and the accession number is A0A6G7K2L4.
TMPY-06287	SARS-CoV-2 Spike S1+S2 Protein (T95I & G142D & E154K & L452R & E484Q & D614G & P681R & Q1071H, His & Avi), Biotinylated	SARS-CoV-2	Baculovirus Insect Cells
	SARS-CoV-2 Spike S1+S2 Protein (T95I & G142D & E154K & L452R & E484Q & D614G & P681R & Q1071H, His & Avi), Biotinylated is expressed in Baculovirus insect cells with His and Avi tag. The predicted molecular weight is 136.32 kDa and the accession number is A0A6G7K2L4.
TMPY-06386	SARS-CoV-2 Spike S1 Protein (G75V & T76I & R246N & 247 deletion & 253 deletion & L452Q & F490S & D614G, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike S1 Protein (G75V & T76I & R246N & 247 deletion & 253 deletion & L452Q & F490S & D614G, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.17 kDa and the accession number is A0A6G7K2L4.
TMPY-06406	SARS-CoV-2 Spike S1+S2 Protein (G75V & T76I & R246N & 247, 253 deletion & L452Q & F490S & D614G & T859N, His)	SARS-CoV-2	Baculovirus Insect Cells
	SARS-CoV-2 Spike S1+S2 Protein (G75V & T76I & R246N & 247, 253 deletion & L452Q & F490S & D614G & T859N, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 134.11 kDa and the accession number is A0A6G7K2L4.
TMPY-06185	SARS-CoV-2 Spike S1+S2 Protein (D80A & 242-244 deletion & R246I & K417N & E484K & N501Y & D614G & A701V, His)	SARS-CoV-2	Baculovirus Insect Cells
	SARS-CoV-2 Spike S1+S2 Protein (D80A & 242-244 deletion & R246I & K417N & E484K & N501Y & D614G & A701V, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 134 kDa and the accession number is A0A6G7K2L4.
TMPY-06421	SARS-CoV-2 Spike S1 Protein (T95I & Y144S & Y145N & R346K & E484K & N501Y & D614G & P681H, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike S1 Protein (T95I & Y144S & Y145N & R346K & E484K & N501Y & D614G & P681H, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.36 kDa and the accession number is A0A6G7K2L4.
TMPY-06394	SARS-CoV-2 Spike S1+S2 Protein (242-244 deletion & D80A & R246I & K417N & E484K & N501Y & D614G & A701V, His & Avi), Biotinylated	SARS-CoV-2	Baculovirus Insect Cells
	SARS-CoV-2 Spike S1+S2 Protein (242-244 deletion & D80A & R246I & K417N & E484K & N501Y & D614G & A701V, His & Avi), Biotinylated is expressed in Baculovirus insect cells with His and Avi tag. The predicted molecular weight is 135.82 kDa and the accession number is A0A6G7K2L4.
TMPY-06260	SARS-CoV-2 Spike S1 Protein (242-244 deletion & L18F & D80A & D215G & R246I & K417N & E484K & N501Y & D614G, His & Avi), Biotinylated	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike S1 Protein (242-244 deletion & L18F & D80A & D215G & R246I & K417N & E484K & N501Y & D614G, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 77.84 kDa and the accession number is A0A6G7K2L4.
TMPY-06129	SARS-CoV-2 Spike S1 Protein (L18F & D80A & D215G & LAL242-244 deletion & R246I & K417N & E484K & N501Y & D614G, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike S1 Protein (L18F & D80A & D215G & LAL242-244 deletion & R246I & K417N & E484K & N501Y & D614G, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76 kDa and the accession number is A0A6G7K2L4.
TMPY-06125	SARS-CoV-2 Spike S1+S2 Protein (L18F & D80A & D215G & LAL242-244 deletion & R246I & K417N & E484K & N501Y & D614G & A701V, His)	SARS-CoV-2	Baculovirus Insect Cells
	SARS-CoV-2 Spike S1+S2 Protein (L18F & D80A & D215G & LAL242-244 deletion & R246I & K417N & E484K & N501Y & D614G & A701V, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 134 kDa and the accession number is A0A6G7K2L4.
TMPY-06171	SARS-CoV-2 Spike S1+S2 Protein (L18F & D80A & D215G & LAL242-244 deletion & R246I & K417N & E484K & N501Y & D614G & A701V, His), Biotinylated	SARS-CoV-2	Baculovirus Insect Cells
	SARS-CoV-2 Spike S1+S2 Protein (L18F & D80A & D215G & LAL242-244 deletion & R246I & K417N & E484K & N501Y & D614G & A701V, His), Biotinylated is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 134 kDa and the accession number is A0A6G7K2L4.
TMPY-06131	SARS-CoV-2 Spike S1+S2 Protein (L18F & T20N & P26S & D138Y & R190S & K417T & E484K & N501Y & D614G & H655Y & T1027I, His)	SARS-CoV-2	Baculovirus Insect Cells
	SARS-CoV-2 Spike S1+S2 Protein (L18F & T20N & P26S & D138Y & R190S & K417T & E484K & N501Y & D614G & H655Y & T1027I, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 134.4 kDa and the accession number is A0A6G7K2L4.
TMPY-06159	SARS-CoV-2 Spike S1+S2 Protein (L18F & T20N & P26S & D138Y & R190S & K417T & E484K & N501Y & D614G & H655Y & T1027I & V1176F, His)	SARS-CoV-2	Baculovirus Insect Cells
	SARS-CoV-2 Spike S1+S2 Protein (L18F & T20N & P26S & D138Y & R190S & K417T & E484K & N501Y & D614G & H655Y & T1027I & V1176F, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 134.5 kDa and the accession number is A0A6G7K2L4.
TMPJ-00781	LR3-IGF-1 Protein, Mouse, Recombinant (His) IGF1,insulin-like gr...	Mouse	E. coli
	Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mouse IGF-I is synthesized as two precursor isoforms with alternate N- and C-terminal propeptides. These isoforms are differentially expressed by various tissues. Mature mouse IGF-I shares 94% and 99% aa sequence identity with human and rat IGF-I, respectively, and exhibits cross-species activity. It shares 60% aa sequence identity with mature mouse IGF-II. IG...
TMPJ-01159	CD16/FCGR3 Protein, Mouse, Recombinant (His) IgG Fc receptor II	Mouse	HEK293 Cells
	Low affinity immunoglobulin gamma Fc region receptor III (Fc gamma RIII/CD16) is a member of the Ig superfamily. Based on close relationships in their extracellular domains, the Fc gamma Rs have been divided into three classes composing of Fc gamma RI (CD64), Fc gamma RII (CD32), and Fc gamma RIII (CD16). Each group may be encoded by multiple genes and exist in different isoforms depending on species and cell type. Mouse CD16 is a type I transmembrane protein having two extracellular Ig-like dom...
TMPJ-01337	IL-21R Protein, Mouse, Recombinant (aa 20-236, His) Nilr,IL-21R,Int...	Mouse	HEK293 Cells
	Interleukin-21 receptor (IL-21R) is a type I transmembrane glycoprotein within the class I cytokine receptor family, type 4 subfamily. IL-21R is expressed mainly on B cells, NK cells, and activated T cells, but is also found on dendritic cells, alternatively activated macrophages, intestinal lamina propria fibroblasts and epithelial cells, and keratinocytes. Both IL-21 and IL-4 are necessary for efficient B cell IgG1 production and normal germinal center architecture. B cell IL-21 R engagement i...
TMPJ-01056	IL-18 Protein, Mouse, Recombinant (His) Interferon γ-induci<...	Mouse	E. coli
	Interleukin-18 (IL-18）is a protein which belongs to the IL-1 family. It is expressed as a 24 kDa precursor by endothelial and epithelial cells, keratinocytes, gamma δ T cells, and phagocytes. Mature mouse IL-18 shares 63% and 91% amino acid sequence identity with mouse and rat IL-18, respectively. IL-18 binds to the widely expressed IL-18 R alpha which recruits IL-18 R beta to form the signaling receptor complex. Its bioactivity is negatively regulated by interactions with IL-18 binding proteins...
TMPJ-00129	BTLA Protein, Human, Recombinant (His) B- and T-Lymphocyte-Associated Protei<...	Human	HEK293 Cells
	B- and T-Lymphocyte Attenuator (BTLA) is a single-pass type I membrane protein containing 1 Ig-like V-type (immunoglobulin-like) domain. BTLA expression is induced during activation of T cells, and BTLA remains expressed on Th1 cells but not Th2 cells. Like PD1 and CTLA4, BTLA interacts with a B7 homolog, B7H4. However, unlike PD-1 and CTLA-4, BTLA displays T-Cell inhibition via interaction with tumor necrosis family receptors (TNF-R), not just the B7 family of cell surface receptors. BTLA is a ...
TMPJ-00091	G-CSF Protein, Mouse, Recombinant (His) Csf3,G-CSF,Granulocyte colony-stimulat...	Mouse	HEK293 Cells
	Granulocyte colony-stimulating factor (G-CSF) is a growth factor and an essential cytokine which belongs to the IL-6 superfamily. Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. G-CSF binding to its receptor G-CSF-R which belongs to the cytokine receptor type I family depends on the interaction of ...
TMPH-01248	ADAR Protein, Human, Recombinant (His & SUMO) ADAR1,IFI-4,136 kDa double-st...	Human	E. coli
	Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translation by changing codons and hence the amino acid sequence of proteins; pre-mRNA splicing by altering splice site recognition sequences; RNA stability by changing sequences involved in nuclease recognition; genetic stability in the case of RNA virus genomes by changing sequences duri...
TMPY-01052	R-Cadherin/CDH4 Protein, Human, Recombinant (His) R-CAD,cadherin 4, type 1, R	Human	HEK293 Cells
	The cadherin superfamily is a large family that engage in both homo- and heterotypic, calcium-dependent, cell-cell adhesion events, and can be divided into at least four subfamilies based on the extracellular (EC) regions and cytoplasmic domains, that is: classical cadherins, desmosomal cadherins, protocadherins, and cadherin-like molecules. Human cadherin 4, type 1, R-cadherin (retinal), also known as CDH4, CAD4 and RCAD, is a classical cadherin from the cadherin superfamily. It is a calcium-de...

重组蛋白

IGF1R/CD221 Protein, Human, Recombinant (His)

Cat.No: TMPY-00834

Species: Human

Expression System: HEK293 Cells

TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His)

Cat.No: TMPY-01459

Species: Human

Expression System: HEK293 Cells

TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-02535

Species: Mouse

Expression System: HEK293 Cells

IL-2 Superkine Protein, Human, Recombinant (L100F, R101D, L105V, I106V, I112F)

Cat.No: TMPJ-01464

Species: Human

Expression System: HEK293 Cells

TCN1 Protein, Human, Recombinant (His)

Cat.No: TMPH-02215

Species: Human

Expression System: P. pastoris (Yeast)

TCN1 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-02216

Species: Human

Expression System: E. coli

IGF1R/CD221 Protein, Human, Recombinant (aa 31-932, His & Avi), Biotinylated

Cat.No: TMPK-00456

Species: Human

Expression System: HEK293 Cells

IGF1R/CD221 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00658

Species: Cynomolgus

Expression System: HEK293 Cells

IGF1R/CD221 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00455

Species: Human

Expression System: HEK293 Cells

IGF1R/CD221 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-06905

Species: Human

Expression System: HEK293 Cells

IGF1R/CD221 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04360

Species: Human

Expression System: Baculovirus Insect Cells

TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01639

Species: Mouse

Expression System: HEK293 Cells

TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05475

Species: Human

Expression System: HEK293 Cells

GLO1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01618

Species: Mouse

Expression System: E. coli

CSF1R Protein, Human, Recombinant (Domain I&II&III, His)

Cat.No: TMPY-05045

Species: Human

Expression System: HEK293 Cells

SARS-CoV-2 Spike RBD Protein (R408I, His)

Cat.No: TMPY-05958

Species: SARS-CoV-2

Expression System: HEK293 Cells

SARS-CoV-2 Nucleocapsid Protein (A119S & R203K & G204R & M234I, His)

Cat.No: TMPY-06202

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 Spike S1 NTD Protein (T19R & T95I & G142D & 156-157 deletion & R158G, His)

Cat.No: TMPY-06422

Species: SARS-CoV-2

Expression System: HEK293 Cells

SARS-CoV-2 Spike S1 Protein (T19R & T95I & E156G & 157-158 deletion & L452R & T478K & D614G & P681R, His)

Cat.No: TMPY-06444

Species: SARS-CoV-2

Expression System: HEK293 Cells

SARS-CoV-2 Spike S1 Protein (T95I & G142D & E154K & L452R & E484Q & D614G & P681R, His)

Cat.No: TMPY-06251

Species: SARS-CoV-2

Expression System: HEK293 Cells

SARS-CoV-2 Spike S1 Protein (T95I & G142D & E154K & L452R & E484Q & D614G & P681R, His & Avi), Biotinylated

Cat.No: TMPY-06293

Species: SARS-CoV-2

Expression System: HEK293 Cells

SARS-CoV-2 Spike S1 Protein (T19R & T95I & G142D & Y145H & E156G & 157-158 deletion & A222V & L452R & T478K & D614G & P681R, His)

Cat.No: TMPY-06443

Species: SARS-CoV-2

Expression System: HEK293 Cells

SARS-CoV-2 Spike S1 NTD Protein (L18F & D80A & D215G & LAL242-244 deletion & R246I, His)

Cat.No: TMPY-06122

Species: SARS-CoV-2

Expression System: HEK293 Cells

SARS-CoV-2 Spike S1+S2 Protein (T95I & G142D & E154K & L452R & E484Q & D614G & P681R & Q1071H, His)

Cat.No: TMPY-06271

Species: SARS-CoV-2

Expression System: Baculovirus Insect Cells

SARS-CoV-2 Spike S1+S2 Protein (T95I & G142D & E154K & L452R & E484Q & D614G & P681R & Q1071H, His & Avi), Biotinylated

Cat.No: TMPY-06287

Species: SARS-CoV-2

Expression System: Baculovirus Insect Cells

SARS-CoV-2 Spike S1 Protein (G75V & T76I & R246N & 247 deletion & 253 deletion & L452Q & F490S & D614G, His)

Cat.No: TMPY-06386

Species: SARS-CoV-2

Expression System: HEK293 Cells

SARS-CoV-2 Spike S1+S2 Protein (G75V & T76I & R246N & 247, 253 deletion & L452Q & F490S & D614G & T859N, His)

Cat.No: TMPY-06406

Species: SARS-CoV-2

Expression System: Baculovirus Insect Cells

SARS-CoV-2 Spike S1+S2 Protein (D80A & 242-244 deletion & R246I & K417N & E484K & N501Y & D614G & A701V, His)

Cat.No: TMPY-06185

Species: SARS-CoV-2

Expression System: Baculovirus Insect Cells

SARS-CoV-2 Spike S1 Protein (T95I & Y144S & Y145N & R346K & E484K & N501Y & D614G & P681H, His)

Cat.No: TMPY-06421

Species: SARS-CoV-2

Expression System: HEK293 Cells

SARS-CoV-2 Spike S1+S2 Protein (242-244 deletion & D80A & R246I & K417N & E484K & N501Y & D614G & A701V, His & Avi), Biotinylated

Cat.No: TMPY-06394

Species: SARS-CoV-2

Expression System: Baculovirus Insect Cells

SARS-CoV-2 Spike S1 Protein (242-244 deletion & L18F & D80A & D215G & R246I & K417N & E484K & N501Y & D614G, His & Avi), Biotinylated

Cat.No: TMPY-06260

Species: SARS-CoV-2

Expression System: HEK293 Cells

SARS-CoV-2 Spike S1 Protein (L18F & D80A & D215G & LAL242-244 deletion & R246I & K417N & E484K & N501Y & D614G, His)

Cat.No: TMPY-06129

Species: SARS-CoV-2

Expression System: HEK293 Cells

SARS-CoV-2 Spike S1+S2 Protein (L18F & D80A & D215G & LAL242-244 deletion & R246I & K417N & E484K & N501Y & D614G & A701V, His)

Cat.No: TMPY-06125

Species: SARS-CoV-2

Expression System: Baculovirus Insect Cells

SARS-CoV-2 Spike S1+S2 Protein (L18F & D80A & D215G & LAL242-244 deletion & R246I & K417N & E484K & N501Y & D614G & A701V, His), Biotinylated

Cat.No: TMPY-06171

Species: SARS-CoV-2

Expression System: Baculovirus Insect Cells

SARS-CoV-2 Spike S1+S2 Protein (L18F & T20N & P26S & D138Y & R190S & K417T & E484K & N501Y & D614G & H655Y & T1027I, His)

Cat.No: TMPY-06131

Species: SARS-CoV-2

Expression System: Baculovirus Insect Cells

SARS-CoV-2 Spike S1+S2 Protein (L18F & T20N & P26S & D138Y & R190S & K417T & E484K & N501Y & D614G & H655Y & T1027I & V1176F, His)

Cat.No: TMPY-06159

Species: SARS-CoV-2

Expression System: Baculovirus Insect Cells

LR3-IGF-1 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00781

Species: Mouse

Expression System: E. coli

CD16/FCGR3 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-01159

Species: Mouse

Expression System: HEK293 Cells

IL-21R Protein, Mouse, Recombinant (aa 20-236, His)

Cat.No: TMPJ-01337

Species: Mouse

Expression System: HEK293 Cells

IL-18 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-01056

Species: Mouse

Expression System: E. coli

BTLA Protein, Human, Recombinant (His)

Cat.No: TMPJ-00129

Species: Human

Expression System: HEK293 Cells

G-CSF Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00091

Species: Mouse

Expression System: HEK293 Cells

ADAR Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01248

Species: Human

Expression System: E. coli

R-Cadherin/CDH4 Protein, Human, Recombinant (His)

Cat.No: TMPY-01052

Species: Human

Expression System: HEK293 Cells

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