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Cat. No. | Product Name | Target | Signaling Pathways |
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T20358 |
Hydroquinone diacetate
NSC-9277,NSC9277,对二乙酰氧基苯,NSC 9277 |
Antioxidant | oxidation-reduction |
Hydroquinone diacetate (NSC-9277) 是一种 OH• 抑制剂,IC50 为 7.59 μM。 | |||
T71887 |
Hydroquinone monobenzoate
|
Others | Others |
Hydroquinone monobenzoate is an oxidoreductant and potential topoisomerase II inhibitor commercially used in skin whitening treatments and photography development. It may induce DNA damage. | |||
T7540 |
2,5-Di-tert-butylhydroquinone
BHQ,2,5-二特丁基对苯二酚 |
Calcium Channel; Lipoxygenase; COX | Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience |
2,5-Di-tert-butylhydroquinone (BHQ) 是一种有效和选择性的内质网 Ca2+-ATPase 抑制剂,可调节5-LO 以及COX-2活性,IC50分别为 1.8 和 14.1 μM。 | |||
T123888 |
Tetrachlorohydroquinone dimethyl ether
|
Others | Others |
Tetrachlorohydroquinone dimethyl ether 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T123888。 | |||
T131092 |
2-Prenylhydroquinone-1-glucoside
|
Others | Others |
2-Prenylhydroquinone-1-glucoside 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131092。 | |||
T36507 |
Tetrachlorohydroquinone
|
Others | Others |
Tetrachlorohydroquinone (TCHQ) is a metabolite of the organochlorine biocide pentachlorophenol. It is cytotoxic to RTL-W1 rainbow trout liver cells (EC50 = 1.55 μM in a neutral red assay). TCHQ increases production of reactive oxygen species (ROS), inhibits apoptosis, and induces loss of the mitochondrial membrane potential and necrosis in splenocytes. In vivo, TCHQ induces glutathione (GSH) depletion in mouse liver. | |||
T65486 |
Trimethylhydroquinone
|
Others | Others |
Trimethylhydroquinone 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65486,CAS号为 700-13-0。 | |||
T3647 |
HTHQ
HX 1171,HTHQ(1-O-Hexyl-2,3,5-trimethylhydroquinone),1-O-hexyl-2,3,5-trimethylhydroquinone |
Reactive Oxygen Species | Immunology/Inflammation; Metabolism; NF-κB |
HTHQ (HTHQ(1-O-Hexyl-2,3,5-trimethylhydroquinone)) 是一种强力的亲脂性酚类抗氧化剂。它通过与活性氧直接反应,清除 ROS,从而形成更稳定的自由基,具有很强的抗氧化活性。 | |||
T60303 |
Collagen-IN-1
|
Others | Others |
Collagen-IN-1 (compound 3) is an ortho-carbonyl hydroquinone derivative exhibiting selective inhibition of collagen. It non-competitively inhibits agonist-induced platelet aggregation, with an IC50 value of 1.77 μM. Collagen-IN-1 effectively reduces the expression of P-selectin, activation of glycoprotein IIb/IIIa, and release of adenosine triphosphate and CD63 from platelets. This compound holds promise for research into platelet-related thrombosis diseases [1]. | |||
T36369 |
3,6-diacetoxy Phthalonitrile
|
||
3,6-diacetoxy Phthalonitrile is a fluorescent probe for monitoring intracellular pH by flow cytometry in living cells. It rapidly crosses cell membranes and is cleaved by cytosolic esterases to form the fluorescent pH indicator 2,3-dicyano-hydroquinone (DCH), which is excited at UV wavelengths. DCH can be excited at 351 nm, with pH-dependent emission in the range of 450-476 nm (pH 5.0-10.0) using a potassium-based buffer. | |||
T70222 |
Ethonafide
|
Others | Others |
Ethonafide is an anthracene-containing derivative of amonafide that belongs to the azonafide series of anticancer agents. The lack of cross-resistance in multidrug-resistant cancer cell lines and the absence of a quinone and hydroquinone moiety make ethonafide a potentially less cardiotoxic replacement for existing anthracene-containing anticancer agents. Ethonafide was cytotoxic against three human prostate cancer cell lines at nanomolar concentrations. Ethonafide was found to be better tolerat... | |||
T36650 |
Ansatrienin B
|
Others | Others |
Ansatrienin B is an ansamycin antibiotic and antifungal agent first isolated from S. collinus and S. rishiriensis., In fetal rat long bones, it is an inhibitor of parathyroid hormone-induced calcium release (IC50 = 21 nM), which is a measure of bone resorption, and pp60c-src kinase (IC50 = 50 nM). It is an inhibitor of translation at the protein synthesis stage by specific inhibition of L-leucine incorporation (IC50 = 58 nM in A549 cells). It also inhibits TNF-α-induced expression of intercellul... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T35749 |
Thymohydroquinone
Thymoquinol |
Antioxidant; Reactive Oxygen Species | Immunology/Inflammation; Metabolism; NF-κB; oxidation-reduction |
Thymohydroquinone (Thymoquinol) 是中药材百里香、牛至和其他唇形科植物中含有的单萜酚类化合物。 Thymohydroquinone 抑制癌细胞生长、减少氧化应激和调节炎症反应,在无细胞实验中清除2,2-二苯基-1-picrylhydrazyl 自由基(IC50 = 2.4 μg/ml),在浓度为1.6至6.4 μg/ml 的氧自由基吸收能力(ORAC)实验中,它的Trolox 当量值为2.6胸腺对苯二酚对A2780、OVCAR-8和CIS-A2780卵巢癌细胞(IC50分别为3.1、8.9和9.8 μM)和人卵巢永生化上皮细胞(IC50 = 14 μM)的生长有抑制作用,体外对恶性疟原虫也有抑制作用(IC50 = 15.9 μM)。 | |||
TN1521 |
Colutehydroquinone
|
Antifection; Antifungal | Microbiology/Virology |
Colutehydroquinone 是一种从Colutea arborescens 的根皮中提取的异黄酮,具有抗真菌活性。 | |||
T38092 |
2,6-Dimethylhydroquinone
|
Others | Others |
2,6-Dimethylhydroquinone is an endogenous metabolite. | |||
T0501 |
Mequinol
4-Hydroxyanisole,Leucobasal,对苯二酚单甲醚,4-Methoxyphenol |
Others | Others |
Mequinol (Leucobasal) 是一种Mercurialis spp 的生物活性成分,常用于皮肤褪色。 | |||
T0473 |
Arbutin
Uva,p-Arbutin,p-Arbutin,熊果苷,β-Arbutin |
Tyrosinase | Proteases/Proteasome |
Arbutin (p-Arbutin) 是一种从熊果植物 Arctostaphylos uvaursi 中分离出的天然多酚,具有抗氧化,抗炎和抗肿瘤特性。它是一种脱色剂,也是一种黑色素细胞中酪氨酸酶的竞争性抑制剂,对单酚酶的 Kiapp 值为 1.42 mM;对二酚酶Kiapp 的值为 0.9 mM。 | |||
T81009 |
Tetrahydroauroglaucin
|
||
Tetrahydroauroglaucin,一种对苯二酚的成员,表现出抗氧化活性。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00110 |
UGT72B1 Protein, Arabidopsis thaliana, Recombinant (His & Myc)
Probable hydroquinone glucosyltransferase,Arbutin s... |
Arabidopsis thaliana | E. coli |
Bifunctional O-glycosyltransferase and N-glycosyltransferase that can detoxify xenobiotics. Possesses high activity to metabolize the persistent pollutants 2,4,5-trichlorophenol (TCP) and 3,4-dichloroaniline (DCA). Also active on benzoates and benzoate derivatives in vitro. UGT72B1 Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 60.4 kDa and the accession number is Q9M156. | |||
TMPH-01277 |
ENOX2 Protein, Human, Recombinant
ENOX2,APK1 antigen,Cytosolic ovarian carcinoma antigen 1,COV... |
Human | E. coli |
May be involved in cell growth. Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide-thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 22 minutes and play a role in control of the ultradian cellular biol... | |||
TMPH-01278 |
ENOX2 Protein, Human, Recombinant (His & Myc)
Cytosolic ovarian carcinoma antigen 1,Ecto-NOX disulfide-thi... |
Human | E. coli |
May be involved in cell growth. Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide-thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 22 minutes and play a role in control of the ultradian cellular biol... | |||
TMPH-01276 |
ENOX1 Protein, Human, Recombinant (His)
Ecto-NOX disulfide-thiol exchanger 1,ENOX1,cNOX,cCNOX |
Human | E. coli |
Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide-thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 24 minutes and play a role in control of the ultradian cellular biological clock. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TMIJ-0425 |
(+/-)-1,2-Propylene-d6 Oxide
|
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(+/-)-1,2-Propylene-d6 Oxide (Stabilized with hydroquinone) 是 (+/-)-1,2-Propylene Oxide 的氘代化合物。(+/-)-1,2-Propylene Oxide 的 CAS 号为 75-56-9。 |