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抑制剂 & 化合物

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T76033	Humanin
	Humanin 是一种 24 个氨基酸组成的抗凋亡肽，是Bax 抑制剂。Humanin 可以阻止Bax 从细胞质向线粒体的转运，阻断Bax 由活性构象向活性构象的转变。Humanin 是一种线粒体相关肽，具有对抗 AD 相关神经毒性的神经保护作用。Humanin 还可以改善动物的整体胰岛素敏感性。Humanin 与衰老有关。HNG，是 Humanin 的 14号位置的丝氨酸被甘氨酸取代的类似物。
TP1524	AGA-(C8R) HNG17, Humanin derivative
	This peptide is a potent humanin (HN) derivative. It completely suppresses neuronal cell death by Alzheimer's disease-relevant insults.
T82154	Humanin C8A-HN
	Humanin C8A-HN是一种生物活性肽，在该化合物中，原有的护脑素(HN)对神经元细胞死亡具有的保护作用被削弱，原因是Cys8位点的氨基酸被Ala替代了。
T76508	(Gly14)-Humanin (human)
	'(Gly14)-Humanin (human) (14-Glycine-Humanin (human)) 为Humanin的一种变体，通过将第14位的丝氨酸替换为甘氨酸(Gly)得到。此化合物展现出抗细胞凋亡及神经保护作用。'
TP1856	Colivelin	Beta Amyloid; STAT	JAK/STAT signaling; Neuroscience; Stem Cells
	Colivelin 是一种神经保护肽和 STAT3 的激活剂，是一种合成的杂合肽，可增强 humanin (HN) 的神经保护作用。它通过激活 STAT3 在体外抑制神经元死亡，具有潜力用于阿尔茨海默病和缺血性脑损伤的相关研究。
TP1278	Colivelin TFA (867021-83-8 free base) Colivelin TFA
	Colivelin (TFA) is a hybrid peptide composed of ADNF and AGA-(C8R)HNG17, a potent Humanin (HN) derivative.
T75833	HNGF6A TFA
	HNGF6A TFA 是一种人类素类似物。HNGF6A TFA 可以增加葡萄糖刺激的胰岛素分泌和葡萄糖代谢，并可用于糖尿病的研究。HNGF6A TFA 在氧化应激期间抑制ROS 的产生。HNGF6A TFA 可以在体内预防内皮功能障碍和动脉粥样硬化。

化合物

AGA-(C8R) HNG17, Humanin derivative

(Gly14)-Humanin (human)

Target: Beta Amyloid, STAT

Colivelin TFA (867021-83-8 free base)

Cat.No: TP1278

Synonym: Colivelin TFA

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-01502	Humanin Protein, Human, Recombinant (GST) Humanin,Humanin mitochondrial,MT-RNR2	Human	E. coli
	Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by multiple different familial Alzheimer disease genes and amyloid-beta proteins in Alzheimer disease. Mediates its neuroprotective effect by interacting with a receptor complex composed of IL6ST/GP130, IL27RA/WSX1 and CNTFR. Also acts as a ligand for G-protein coupled receptors FPR2/FPRL1 and FPR3/FPRL2. Inhibits amyloid-beta protein 40 fibril formation. Also inhibits amyloid-beta protein 42 fibril formation....
TMPH-01503	Humanin Protein, Human, Recombinant (hFc) MT-RNR2,Humanin,Humanin mitochondrial	Human	HEK293 Cells
	Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by multiple different familial Alzheimer disease genes and amyloid-beta proteins in Alzheimer disease. Mediates its neuroprotective effect by interacting with a receptor complex composed of IL6ST/GP130, IL27RA/WSX1 and CNTFR. Also acts as a ligand for G-protein coupled receptors FPR2/FPRL1 and FPR3/FPRL2. Inhibits amyloid-beta protein 40 fibril formation. Also inhibits amyloid-beta protein 42 fibril formation....

重组蛋白

Humanin Protein, Human, Recombinant (GST)

Cat.No: TMPH-01502

Species: Human

Expression System: E. coli

Humanin Protein, Human, Recombinant (hFc)

Cat.No: TMPH-01503

Species: Human

Expression System: HEK293 Cells

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