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Search Results for " hsps "

Targets Recommended: p38 MAPK

4

抑制剂 & 化合物

1

天然产物

2

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T7661	SD-169 SD 169,1H-吲哚-5-甲酰胺	p38 MAPK	MAPK
	SD-169 (SD 169) 是一种可口服的 ATP 竞争性MAPK p38α抑制剂，IC50值为 3.2 nM。它对p38β MAPK 的IC50值为 122 nM。它通过抑制 T 细胞的浸润和活化阻止糖尿病的发展。
T2444	KNK437 Heat Shock Protein Inhibitor I	HSP	Cytoskeletal Signaling; Metabolism
	KNK437 (Heat Shock Protein Inhibitor I) 是一种 HSP 抑制剂，抑制 HSP40，HSP70 和 HSP105 的活化。
T5008	Teprenone Tetraprenylacetone,Geranylgeranylacetone,替普瑞酮	HSP	Cytoskeletal Signaling; Metabolism
	Teprenone (Geranylgeranylacetone) 是一种热休克蛋白诱导剂，有抗溃疡作用。
T36865	Heat Shock Protein Inhibitor II	Others	Others
	Heat shock protein (Hsp) inhibitor II is the active form of Hsp inhibitor I and a benzylidene lactam compound that prevents the synthesis of inducible Hsps, such as Hsp105, Hsp72, and Hsp40. Hsp inhibitor II decreases Hsp72 synthesis in vivo and reduces thermotolerance of tumors in SCC VII tumor-containing mice. At 100 μM, it inhibits the development of thermotolerance in COLO 320 DM cells. Inhibition of Hsp70 with Hsp inhibitor II in combination with amphotericin B increases susceptibility of A...

化合物

Cat.No: T7661

Synonym: SD 169,1H-吲哚-5-甲酰胺

Target: p38 MAPK

Cat.No: T2444

Synonym: Heat Shock Protein Inhibitor I

Target: HSP

Cat.No: T5008

Synonym: Tetraprenylacetone,Geranylgeranylacetone,替普瑞酮

Target: HSP

Heat Shock Protein Inhibitor II

Cat.No: T36865

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T1153	Trimethoprim NIH 204,BW 56-72,甲氧苄啶,NSC-106568	DHFR; DNA/RNA Synthesis; Antifolate; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	Trimethoprim (NSC-106568) 是抑菌抗生素，也是具有口服活性的二氢叶酸还原酶抑制剂。它对多种革兰氏阳性和革兰氏阴性需氧细菌具有活性，可用于尿路感染，肺孢子菌肺炎和志贺氏菌病的研究。

天然产物

Cat.No: T1153

Synonym: NIH 204,BW 56-72,甲氧苄啶,NSC-106568

Target: DHFR, DNA/RNA Synthesis, Antifolate, Antibacterial, Antibiotic

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00915	HSP40 Protein, Human, Recombinant (His) HDJ1,HSPF1,DNAJ1,Heat Shock 40 kDa Protein 1,HSP40,hDj-1,DNA...	Human	E. coli
	DnaJ Homolog Subfamily B Member 1 (DNAJB1) is a member of the heat shock protein family. Heat shock proteins (HSPs) are a highly conserved family of stress response proteins. HSPs function primarily as molecular chaperones, facilitating the folding of other cellular proteins, preventing protein aggregation, or targeting improperly folded proteins to specific degradative pathways. DNAJB1 regulates cellular processes by aiding in the folding, transport and assembly. DNAJB1 contains a J-domain whic...
TMPY-02072	HSF1 Protein, Human, Recombinant (His) HSTF1,heat shock transcription factor 1	Human	E. coli
	Heat shock factor protein 1, also known as heat shock transcription factor 1, HSF1, and HSTF1, is a cytoplasm and nucleus protein that belongs to the HSF family. HSF1 is the major transcription factor of HSPs (heat shock proteins) in response to various stresses. Wild type HSF1 (heat shock transcriptional factor 1) is normally inactive. HSF1 / HSTF1 is a DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable...

重组蛋白

HSP40 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00915

Species: Human

Expression System: E. coli

HSF1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02072

Species: Human

Expression System: E. coli

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