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Search Results for " herpesviruses "

Targets Recommended: HBV Reverse Transcriptase Telomerase

10

抑制剂 & 化合物

1

天然产物

2

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T7447	Adefovir	HBV; Reverse Transcriptase; Telomerase	DNA Damage/DNA Repair; Microbiology/Virology
	Adefovir 是一种单磷酸腺苷类似物抗病毒剂，在细胞内转化为 Adefovir diphosphate 后可抑制HBVDNA 聚合酶。它在 HepG2.2.15 细胞系中对HBV 的IC50为 0.7 μM。它对多种病毒(包括HBV 和疱疹病毒)具有良好的抗病毒活性。
T0863	Idoxuridine IDU,碘苷,SKF 14287,5-Iodo-2′-deoxyuridine,NSC 39661,5-IUdR,Dendrid	Antifection; HSV	Microbiology/Virology
	Idoxuridine (Dendrid) 是一种抑制病毒 DNA 合成的脱氧尿苷类似物，用作抗病毒剂。
T0220	Foscarnet sodium Phosphonoformate,膦甲酸钠	Virus Protease; Reverse Transcriptase; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Foscarnet sodium (Phosphonoformate) 是一种病毒 DNA 聚合酶活性抑制剂，可逆地抑制病毒复制。它是一种用于治疗巨细胞病毒性视网膜炎的抗病毒剂。
T31659	Eprociclovir AV10,AV-10,A-5021,A 5021,A5021,AV 10	Antifection	Microbiology/Virology
	Eprociclovir (A-5021) 是一种新型阿昔洛韦类似物，是 EHV1 复制的强效抑制剂，可能用于治疗和/或预防该病毒感染。Eprociclovir 对大多数人类疱疹病毒都有很强的抗疱疹活性。
T80672	1,4-Dihydroxynaphthalene Naphthalene-1,4-diol	HSV	Microbiology/Virology
	1,4-Dihydroxynaphthalene 一种有效的 HSV-1蛋白酶抑制剂，对HCMV蛋白酶有抑制作用，可用于研究疱疹病毒。
TQ0095	Brincidofovir CMX001,HDP-CDV	Others; Antiviral; HSV	Immunology/Inflammation; Microbiology/Virology; Others
	Brincidofovir (HDP-CDV) 是 Cidofovir 的一种具有口服活性的亲脂性形式的前体药物，是一种口服长效的抗病毒药物，有广泛的抗 DNA 病毒活性。
T29093	Valomaciclovir stearate A-174606.0,RP-606,EPB-348,ABT-606,MIV-606	Others	Others
	Valomaciclovir stearate is a DNA polymerase inhibitor. Valomaciclovir stearate is an orally available drug with broad-spectrum antiviral activity against a variety of important herpesviruses, including Epstein-Barr virus, or EBV (the first virus to be dir
T70027	Eprociclovir potassium	Others	Others
	Eprociclovir potassium is a new acyclovir analogue and a potent inhibitor of EHV1 replication and may have potential for the treatment and/or prophylaxis of infections with this virus. Eprociclovir possess potent anti-herpetic activity against most human herpesviruses. A-5021 proved to be about 15-fold more potent than acyclovir in inhibiting viral replication. Eprociclovir inhibits murine herpetic keratitis. A-5021 eyedrops, which are easily applied onto the affected cornea, ameliorated clinica...
T69817	Eprociclovir Na	Others	Others
	Eprociclovir Na is the salt form of Eprociclovir, also known as A-5021, a new acyclovir analogue and a potent inhibitor of EHV1 replication and may have potential for the treatment and/or prophylaxis of infections with this virus. Eprociclovir possess potent anti-herpetic activity against most human herpesviruses. A-5021 proved to be about 15-fold more potent than acyclovir in inhibiting viral replication. Eprociclovir inhibits murine herpetic keratitis. A-5021 eyedrops, which are easily applie...
T68957	Eprociclovir dihydrate	Others	Others
	Eprociclovir dihydrate is a new acyclovir analogue and a potent inhibitor of EHV1 replication and may have potential for the treatment and/or prophylaxis of infections with this virus. Eprociclovir possess potent anti-herpetic activity against most human herpesviruses. A-5021 proved to be about 15-fold more potent than acyclovir in inhibiting viral replication. Eprociclovir inhibits murine herpetic keratitis. A-5021 eyedrops, which are easily applied onto the affected cornea, ameliorated clinica...

化合物

Cat.No: T7447

Target: HBV, Reverse Transcriptase, Telomerase

Cat.No: T0863

Synonym: IDU,碘苷,SKF 14287,5-Iodo-2′-deoxyuridine,NSC 39661,5-IUdR,Dendrid

Target: Antifection, HSV

Foscarnet sodium

Cat.No: T0220

Synonym: Phosphonoformate,膦甲酸钠

Target: Virus Protease, Reverse Transcriptase, DNA/RNA Synthesis

Cat.No: T31659

Synonym: AV10,AV-10,A-5021,A 5021,A5021,AV 10

Target: Antifection

1,4-Dihydroxynaphthalene

Cat.No: T80672

Synonym: Naphthalene-1,4-diol

Target: HSV

Cat.No: TQ0095

Synonym: CMX001,HDP-CDV

Target: Others, Antiviral, HSV

Valomaciclovir stearate

Cat.No: T29093

Synonym: A-174606.0,RP-606,EPB-348,ABT-606,MIV-606

Target: Others

Eprociclovir potassium

Cat.No: T70027

Target: Others

Eprociclovir Na

Cat.No: T69817

Target: Others

Eprociclovir dihydrate

Cat.No: T68957

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T75643	Isoxanthohumol	HSV	Microbiology/Virology
	Isoxanthohumol 是一种从啤酒花和啤酒中提取的一种前黄酮类化合物，对几种人类癌细胞株具有抗增殖活性。Isoxanthohumol对肿瘤细胞肺转移灶的转移或侵袭有抑制作用。Isoxanthohumol具有抗病毒活性，对疱疹病毒（HSV1和HSV2）和牛病毒性腹泻病毒（BVDV）具有抑制作用。

天然产物

Cat.No: T75643

Target: HSV

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-06855	Varicella-zoster virus (VZV) (strain Oka vaccine) Glycoprotein B/gB Protein	VZV	CHO Cells
	Varicella-zoster virus (VZV) is a highly fusogenic virus, but the degree of fusion is dependent on the cell substrate in which the virus is propagated. Varicella-zoster virus (VZV) is classified as an alphaherpesvirus based on its growth characteristics and its ability to become latent in the nervous system of the host. Like all known herpesviruses, VZV encodes a homolog of glycoprotein B (gB). Glycoprotein B (gB) is the most conserved entry glycoprotein among herpesviruses with an amino acid se...
TMPY-06802	HSV 2 (strain 333) Glycoprotein D/gD Protein (His)	HSV2	HEK293 Cells
	Herpes simplex viruses (human herpesviruses types 1 and 2) commonly cause recurrent infection affecting the skin, mouth, lips, eyes, and genitals. Herpes simplex virus type 2 (HSV-2) infection is responsible for significant neurological morbidity, perhaps more than any other virus. Herpes simplex virus type 2–associated neurological disease may result from primary infection or reactivation of latent HSV-2. Common severe infections include encephalitis, meningitis, neonatal herpes, and, in immun...

重组蛋白

Varicella-zoster virus (VZV) (strain Oka vaccine) Glycoprotein B/gB Protein

Cat.No: TMPY-06855

Species: VZV

Expression System: CHO Cells

HSV 2 (strain 333) Glycoprotein D/gD Protein (His)

Cat.No: TMPY-06802

Species: HSV2

Expression System: HEK293 Cells

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