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Search Results for " heparin "
Targets Recommended: Factor Xa Thrombin Autophagy

36

抑制剂 & 化合物

5

天然产物

1

TargetMol 试剂盒

58

重组蛋白

1

同位素标记化合物

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Cat. No. Product Name Form Specificity Of Inhibition
C0113 Magrose Beads Heparin

肝素磁珠

Suspension in bottle 适用于抗凝血因子 III、凝血因子、核酸结合蛋白、脂蛋白、干扰素、类固醇受体、凝血酶及类凝血酶等生物大分子的分离纯化。

TargetMol 试剂盒

肝素磁珠
Cat.No: C0113
Cat. No. Product Name Target Signaling Pathways
T6531 Heparin sodium salt

肝素钠,Sodium heparinate,Heparin sodium

Factor Xa; Thrombin; Autophagy Autophagy; Metabolism; Proteases/Proteasome
Heparin sodium salt (Sodium heparinate) 是一种抗凝血剂,可以干扰血凝过程中的多个环节。Heparin sodium salt 可以与抗凝血酶 III 可逆结合,加快凝血酶因子 IIa 和 Xa 的失活速度,从而发挥抗凝作用。
TP1153L Fibronectin Adhesion-promoting Peptide acetate

Fibronectin Adhesion-promoting Peptide acetate(125720-21-0 free base),Heparin Binding Peptide acetate

Others Others
Fibronectin Adhesion-promoting Peptide acetate (Heparin Binding Peptide acetate)(125720-21-0 free base) 是在纤连蛋白的羧基末端肝素结合结构域中发现的肝素结合氨基酸序列之一。
T4076 Fondaparinux sodium

Natural heparin pentasaccharide Sodium,Fondaparin sodium,磺达肝素(癸)钠,磺达肝癸钠,SR-90107A,Arixtra

Factor Xa Metabolism
Fondaparinux sodium (SR-90107A) 是抗凝血酶依赖性的 factor Xa 抑制剂。
TP2255 heparin cofactor II precursor fragment [Homo sapiens]

Others Others
Heparin cofactor II precursor fragment [Homo sapiens] is a peptide with the sequence H2N-Tyr-Glu-Ile-Thr-Thr-Ile-His-Asn-Leu-Phe-Arg-OH, MW=1406.58.
TP2256 heparin cofactor II precursor (SERPIND1) fragment [Homo sapiens]

Others Others
Heparin cofactor II precursor (SERPIND1) fragment [Homo sapiens] is a peptide with the sequence H2N-Phe-Thr-Val-Asp-Arg- Pro-Phe-Leu-Phe-Leu-Ile-Tyr-Glu-His-Arg-OH, MW=1953.25.
T64262 Heparin Lithium salt

Others Others
Heparin Lithium salt 是一种抗凝剂,能够可逆的结合抗凝血酶III (ATIII)。Heparin Lithium salt 明显阻碍外泌体-细胞相互作用。
TP1153 Fibronectin Adhesion-promoting Peptide

Heparin Binding Peptide

Fibronectin Adhesion-promoting Peptide (Heparin Binding Peptide) is one of the heparin-binding amino acid sequences found in the carboxy-terminal heparin-binding domain of fibronectin.
TP1152 Fibronectin Adhesion-promoting Peptide TFA

Heparin Binding Peptide TFA

Fibronectin Adhesion-promoting Peptide (Heparin Binding Peptide) is one of the heparin-binding amino acid sequences found in the carboxy-terminal heparin-binding domain of fibronectin. It promotes assembly of mesenchymal stem cell (MSC) spheroids into lar
T40711 H-D-Phe-Pip-Arg-pNA dihydrochloride

S-2238 dihydrochloride,H-D-Phe-Pip-Arg-pNA dihydrochloride

Others Others
H-D-Phe-Pip-Arg-pNA dihydrochloride (S-2238 dihydrochloride), a chromogenic substrate, mimics the N-terminal fragment of the A alpha chain of fibrinogen, the native substrate of thrombin. Specifically designed for thrombin detection, H-D-Phe-Pip-Arg-pNA dihydrochloride is employed for the quantification of antithrombin-heparin cofactor (AT-III). The AT-III assay utilizing this substrate is characterized by its sensitivity, accuracy, and ease of implementation.
T26240 Surfen dihydrochloride

Aminokinuride dihydrochloride,Aminoquinuride dihydrochloride,NSC-12155,Aminokinuride 2HCl,Aminoquinuride 2HCl

FGFR; Antiviral; Antibiotic Angiogenesis; Immunology/Inflammation; Microbiology/Virology; Tyrosine Kinase/Adaptors
Surfen dihydrochloride (Aminoquinuride dihydrochloride) 是一种有效的硫酸肝素小分子拮抗剂,具有抗菌和抗病毒活性,抑制炭疽致死因子、凝血因子 X 和致死因子。Surfen dihydrochloride 可抑制普通肝素和低分子量肝素的抗凝活性,抑制肝素的硫酸化和肝素裂解酶的降解。Surfen dihydrochloridn 抑制阻断硫酸乙酰肝素介导的 FGF2 结合和信号转导。Surfen 抑制 SEVI 和精液介导的 HIV 1 型感染增强。
T0155 Argatroban

MCI-9038,阿加曲班,MD-805,Argipidine

Thrombin Proteases/Proteasome
Argatroban (MCI-9038) 是一种选择性的凝血酶抑制剂。
T10820L1 Ciraparantag acetate

Ciraparantag acetate(1438492-26-2 Free base)

Others Others
Ciraparantag acetate 是一种抗凝逆转剂,是一种小分子,专门设计用于通过电荷-电荷相互作用与普通肝素和低分子量肝素非共价结合。它显示出与直接口服抗凝剂 (DOAC) 相似的结合特性。
T22246 Argatroban Monohydrate

阿加曲班一水合物,阿加曲班

Thrombin Proteases/Proteasome
Argatroban Monohydrate 是一种 thrombin 选择性抑制剂。
T13720 Hexadimethrine bromide

1,5-Dimethyl-1,5-diazaundecamethylene polymethobromide,海美溴铵,聚凝胺,Polybrene

Others Others
Hexadimethrine bromide (Polybrene) 是一种阳离子聚合物,可以用于逆转录病毒和慢病毒感染,提高基因转移效率。
T8926 Salcaprozate sodium

8-(2-羟基苯甲酰胺基)辛酸钠,SNAC

Others Others
Salcaprozate sodium (SNAC) 是口服吸收促进剂,有作为口服形式的肝素和胰岛素递送剂的潜力。它可提高非共价大分子络合引起的亲脂性,从而增加小肠上皮细胞的被动跨细胞渗透。
T22323 Enoxaparin sodium

Thrombin Proteases/Proteasome
Enoxaparin sodium 是一种低分子量肝素 (LMWH),已获得美国 FDA 批准,可用于医疗管理的 ST 段心肌梗死 (STEMI) 或 STEMI 及随后的经皮冠状动脉介入治疗 (PCI) 患者。它与抗凝血酶结合并增强其作用,并抑制凝血因子 XIa、IXa、Xa 和 IIa(凝血酶),从而防止血栓形成。
T68002 Naroparcil

Thrombin Proteases/Proteasome
Naroparcil 是一种可口服的硫代苷类化合物,是一种 4-甲基伞形 β-D-木糖苷类似物,在静脉血栓形成(颈静脉)的Wessler淤滞模型中显示出抗血栓形成作用。Naroparcil 增强了凝血酶/肝素辅因子II复合物的形成,诱导了处理兔血浆中硫酸皮肤素样物质的出现,但减少了与(125I)-人α-凝血酶孵育的血浆中的凝血酶/抗凝血酶III复合物的形成。
T24531 NIC

Others Others
NIC is an inhibitor of host invasion. It is also an inhibitor of VEGF binding to immobilized heparin.
TP1959 PM 102

Peptide that reverses the anticoagulant effect of heparin. Potently binds heparin (Kd = 36 nM in vitro).
T11341 FXIa-IN-1

Others Others
FXIa-IN-1 is a potent β-lactam covalent heparin-derived factor XIa (fXIa) inhibitor.
T10820 Ciraparantag

PER977

Others Others
Ciraparantag is an inhibitor of thrombin and factor Xa. Ciraparantag is a broad-spectrum reversal agent for anticoagulants, including unfractionated heparin, low-molecular-weight heparin, and certain direct oral anticoagulants.
T71532 Fondaparinux free base

Others Others
Fondaparinux Free Base is a synthetic pentasaccharide that mediates the interaction of HEPARIN with ANTITHROMBINS and inhibits FACTOR Xa; it is used for prevention of VENOUS THROMBOEMBOLISM after surgery. Fondaparinux is a clinically approved anticoagulant pentasaccharide for the treatment of thrombotic diseases, displays better efficacy and biosafety than other heparin-based anticoagulant drugs.
T31522 Dipropyl sulfone

Others Others
Dipropyl sulfone may function as an enhancer of heparin absorption in the intestine.
T10820L Ciraparantag TFA

PER977 TFA

Others Others
Ciraparantag TFA is an inhibitor of thrombin and factor Xa. Ciraparantag is a broad-spectrum reversal agent for anticoagulants, including unfractionated heparin, low-molecular-weight heparin, and certain direct oral anticoagulants.
T37568 4-Methylumbelliferyl 2-sulfamino-2-deoxy-α-D-Glucopyranoside (sodium salt)

4-Methylumbelliferyl 2-sulfamino-2-deoxy-α-D-Glucopyranoside (4-MU-α-GlcNS) is a fluorogenic substrate of heparin sulphamidase. Heparin sulphamidase cleaves 4-MU-α-GlcNS to yield 4-MU-α-GlcNH2, which is then cleaved by α-glucosaminidase to release the fluorescent product 4-MU, which displays an emission maxima of 445-454 nm. The excitation maxima for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively. 4-MU-α-GlcNS has been used to quantify heparin sulphamidase defi...
T36292 NSC 12

Others Others
NSC 12 is an extracellular trap for fibroblast growth factor 2 (FGF2) that binds FGF2 (Kd = 51 μM) and interferes with its interaction with FGFR1, without affecting the ability of FGF2 to bind heparin or heparin sulfate proteoglycans (HSPGs). NSC 12 also binds several other, but not all, FGF isoforms with Kd values ranging between 16 and 120 μM, preventing them from forming HSPG/FGF/FGFR ternary complexes. NSC 12 inhibits FGF-dependent angiogenesis and tumor cell proliferation in vitro and reduc...
T16377 Odiparcil

SB-424323

Thrombin Proteases/Proteasome
Odiparcil is an orally active beta-d-thioxyloside analog. Odiparcil is an indirect thrombin inhibitor that exerts its anticoagulant effect through activation of antithrombin II (heparin cofactor II). It also has an antithrombotic activity associated with a reduced risk of adverse bleeding events.
T82890 bFGF (119-126)

bFGF (119-126) 为具备生物活性的肽段,对应人类、牛(119-126)、小鼠、大鼠(118-125)以及肝素结合生长因子2(118-125)的相应残基。该肽能够抑制bFGF受体的二聚化及其激活作用。
T36111 L-Iduronic acid sodium salt

Others Others
L-Iduronic acid sodium salt 是一种单糖,是肝素、硫酸乙酰肝素和硫酸皮肤素等糖胺聚糖 (GAG) 的重要成分。
T73751 Lepirudin

Lepirudin为高效的不可逆凝血酶抑制剂,同时是重组水蛭素,主要在肝素诱导的血小板减少症(HIT)中发挥抗凝作用。
T83672 TTAPE-Me

1,1,2,2-tetrakis[4-(2-Trimethylammonioethoxy)-phenylethene

TTAPE-Me是一种聚集诱导发光(AIE)荧光团。它被用于检测阴离子磷脂,包括心磷脂、磷脂酰甘油(PG)和磷脂酰丝氨酸(PS)、核酸,以及阴离子多糖肝素。
T75389 Catechol O-methyltransferase

COMT

Endogenous Metabolite Metabolism
Catechol O-methyltransferase (COMT) 是是调节褪黑激素合成的关键酶,可调节参与调节植物的生长发育,可被具有特定结构的肝素低聚糖抑制。
T39066 H-D-Phe-Pip-Arg-pNA hydrochloride

S-2238 hydrochloride,H-D-Phe-Pip-Arg-pNA hydrochloride

H-D-Phe-Pip-Arg-pNA hydrochloride, a chromogenic substrate, mimics the N-terminal segment of the A alpha chain of fibrinogen, the native substrate of thrombin. It displays specificity towards thrombin and is employed for quantifying antithrombin-heparin cofactor (AT-III). The utilization of H-D-Phe-Pip-Arg-pNA hydrochloride in the AT-III assay enables a sensitive, accurate, and straightforward measurement process.
T84738 Dermatan sulphate sodium

Others Others
Dermatan sulphate sodium,一种具抗血栓活性的糖胺聚糖和凝血酶灭活剂。它通过选择性催化肝素辅因子II使凝血酶灭活,不涉及抗凝血酶III的相互作用。此外,Dermatan sulphate sodium展现出高生物利用度,并能有效减轻Bleomycin引发的肺纤维化伤害。
T36714 Sucrose octasulfate (potassium salt)

Others Others
Sucrose octasulfate (SOS), a component of the gastrointestinal protectant sucralfate, is an alkaline aluminum-sucrose complex that inhibits peptic hydrolysis and raises gastric pH, protecting esophageal epithelium against acid injury. It can bind to exosite II of thrombin (KD = ~1.4 μM) and inhibit its catalytic activity (IC50 = 4.5 μM) and, as such, has been used as a surrogate for heparin. Furthermore, SOS has been shown to inhibit tumor growth in mouse melanoma and lung carcinoma models by pr...
T36370 4-Methylumbelliferyl-α-L-Iduronide (free acid)

Others Others
4-Methylumbelliferyl-α-L-iduronide (free acid) is a fluorogenic substrate for α-L-iduronidase, an enzyme found in cell lysosomes that is involved in the degradation of glycosaminoglycans such as dermatan sulfate and heparin sulfate. 4-Methylumbelliferyl-α-L-iduronide is cleaved by α-L-iduronidase to release the fluorescent moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an...

化合物

Heparin sodium salt
Cat.No: T6531
Synonym: 肝素钠,Sodium heparinate,Heparin sodium
Target: Factor Xa, Thrombin, Autophagy
Fibronectin Adhesion-promoting Peptide acetate
Cat.No: TP1153L
Synonym: Fibronectin Adhesion-promoting Peptide acetate(125720-21-0 free base),Heparin Binding Peptide acetate
Target: Others
Fondaparinux sodium
Cat.No: T4076
Synonym: Natural heparin pentasaccharide Sodium,Fondaparin sodium,磺达肝素(癸)钠,磺达肝癸钠,SR-90107A,Arixtra
Target: Factor Xa
heparin cofactor II precursor fragment [Homo sapiens]
Cat.No: TP2255
Synonym:
Target: Others
heparin cofactor II precursor (SERPIND1) fragment [Homo sapiens]
Cat.No: TP2256
Synonym:
Target: Others
Heparin Lithium salt
Cat.No: T64262
Synonym:
Target: Others
Fibronectin Adhesion-promoting Peptide
Cat.No: TP1153
Synonym: Heparin Binding Peptide
Target:
Fibronectin Adhesion-promoting Peptide TFA
Cat.No: TP1152
Synonym: Heparin Binding Peptide TFA
Target:
H-D-Phe-Pip-Arg-pNA dihydrochloride
Cat.No: T40711
Synonym: S-2238 dihydrochloride,H-D-Phe-Pip-Arg-pNA dihydrochloride
Target: Others
Surfen dihydrochloride
Cat.No: T26240
Synonym: Aminokinuride dihydrochloride,Aminoquinuride dihydrochloride,NSC-12155,Aminokinuride 2HCl,Aminoquinuride 2HCl
Target: FGFR, Antiviral, Antibiotic
Argatroban
Cat.No: T0155
Synonym: MCI-9038,阿加曲班,MD-805,Argipidine
Target: Thrombin
Ciraparantag acetate
Cat.No: T10820L1
Synonym: Ciraparantag acetate(1438492-26-2 Free base)
Target: Others
Argatroban Monohydrate
Cat.No: T22246
Synonym: 阿加曲班一水合物,阿加曲班
Target: Thrombin
Hexadimethrine bromide
Cat.No: T13720
Synonym: 1,5-Dimethyl-1,5-diazaundecamethylene polymethobromide,海美溴铵,聚凝胺,Polybrene
Target: Others
Salcaprozate sodium
Cat.No: T8926
Synonym: 8-(2-羟基苯甲酰胺基)辛酸钠,SNAC
Target: Others
Enoxaparin sodium
Cat.No: T22323
Synonym:
Target: Thrombin
Naroparcil
Cat.No: T68002
Synonym:
Target: Thrombin
NIC
Cat.No: T24531
Synonym:
Target: Others
PM 102
Cat.No: TP1959
Synonym:
Target:
FXIa-IN-1
Cat.No: T11341
Synonym:
Target: Others
Ciraparantag
Cat.No: T10820
Synonym: PER977
Target: Others
Fondaparinux free base
Cat.No: T71532
Synonym:
Target: Others
Dipropyl sulfone
Cat.No: T31522
Synonym:
Target: Others
Ciraparantag TFA
Cat.No: T10820L
Synonym: PER977 TFA
Target: Others
4-Methylumbelliferyl 2-sulfamino-2-deoxy-α-D-Glucopyranoside (sodium salt)
Cat.No: T37568
Synonym:
Target:
NSC 12
Cat.No: T36292
Synonym:
Target: Others
Odiparcil
Cat.No: T16377
Synonym: SB-424323
Target: Thrombin
bFGF (119-126)
Cat.No: T82890
Synonym:
Target:
L-Iduronic acid sodium salt
Cat.No: T36111
Synonym:
Target: Others
Lepirudin
Cat.No: T73751
Synonym:
Target:
TTAPE-Me
Cat.No: T83672
Synonym: 1,1,2,2-tetrakis[4-(2-Trimethylammonioethoxy)-phenylethene
Target:
Catechol O-methyltransferase
Cat.No: T75389
Synonym: COMT
Target: Endogenous Metabolite
H-D-Phe-Pip-Arg-pNA hydrochloride
Cat.No: T39066
Synonym: S-2238 hydrochloride,H-D-Phe-Pip-Arg-pNA hydrochloride
Target:
Dermatan sulphate sodium
Cat.No: T84738
Synonym:
Target: Others
Sucrose octasulfate (potassium salt)
Cat.No: T36714
Synonym:
Target: Others
4-Methylumbelliferyl-α-L-Iduronide (free acid)
Cat.No: T36370
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
T20654 Heparin

Certoparin,Bemiparin,Dalteparin,Adomiparin

Thrombin; Endogenous Metabolite; Antibacterial; Autophagy Autophagy; Metabolism; Microbiology/Virology; Proteases/Proteasome
Heparin (Adomiparin) 是硫酸粘多糖,常在临床医学上当抗凝剂使用。Heparin 在体内实验中显示出部分抗炎活性。
T41031 Protamine sulfate

Thrombin Proteases/Proteasome
Protamine sulfate是一种多阳离子肽类,作为一种抗肝素剂。该化合物能中和肝素的抗凝作用并增强脂质介导的基因转移。
Fr16605 Lupinine

鲁冰花,羽扇豆碱

AChR; AChE Neuroscience
Lupinine 是一种能够抵消乙醇麻醉的生物碱。 Lupinine 是一种 AChE 和 BChE 抑制剂和潜在的 CD69 激活剂,存在于 Loranthus、Calia 和 Lupinus 物种中。它还可以抑制肝素。
T2O2721 L-Cysteine

Thioserine,L-半胱氨酸,cysteine,半胱氨酸,L-(+)-Cysteine

Endogenous Metabolite Metabolism
L-Cysteine (L-(+)-Cysteine) 是人体非必需的含硫氨基酸。L-Cysteine 对蛋白质合成、解毒和多种代谢功能很重要。L-Cysteine 存在于指甲、皮肤和头发的主要蛋白质-角蛋白中,对胶原蛋白的生成、皮肤弹性和质地都很重要。L-Cysteine 是抗氧化剂谷胱甘肽的一种成分,在辅酶A、肝素和生物素等基本生化物质的代谢中起着重要作用,也是氨基酸牛磺酸的制造所必需的。
T4S0797 Berberine

小檗碱,Berberin,Umbellatine,黄连素

Reactive Oxygen Species; Topoisomerase; Endogenous Metabolite; Antibacterial; Antibiotic; Autophagy Autophagy; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
Berberine (Umbellatine) 属于生物碱类天然产物,可以激活 AMPK、抑制 DNA 拓扑异构酶、诱导 ROS 生成。Berberine 具有抗肿瘤、抗菌、降血糖、降血脂等生物学活性。

天然产物

Heparin
Cat.No: T20654
Synonym: Certoparin,Bemiparin,Dalteparin,Adomiparin
Target: Thrombin, Endogenous Metabolite, Antibacterial, Autophagy
Protamine sulfate
Cat.No: T41031
Synonym:
Target: Thrombin
Lupinine
Cat.No: Fr16605
Synonym: 鲁冰花,羽扇豆碱
Target: AChR, AChE
L-Cysteine
Cat.No: T2O2721
Synonym: Thioserine,L-半胱氨酸,cysteine,半胱氨酸,L-(+)-Cysteine
Target: Endogenous Metabolite
Berberine
Cat.No: T4S0797
Synonym: 小檗碱,Berberin,Umbellatine,黄连素
Target: Reactive Oxygen Species, Topoisomerase, Endogenous Metabolite, Antibacterial, Antibiotic, Autophagy
Cat. No. Product Name Species Expression System
TMPJ-00090 FGF-9 Protein, Human, Recombinant

Fibroblast Growth Factor 9,Heparin-Binding Growth F...

Human E. coli
Fibroblast Growth Factor 9 (FGF-9) belongs to the Fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-9 plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. In addition, FGF-9 may have a role in glial c...
TMPJ-00842 FGF-2 Protein, Rat, Recombinant

bFGF,Heparin-Binding Growth Factor 2,FGFB,Fibroblas...

Rat E. coli
FGF-basic is a members of the Fibroblast Growth Factors (FGFs) family. The family constitutes a large family of proteins involved in many aspects of development including cell proliferation, growth, and differentiation. They act on several cell types to regulate diverse physiologic functions including angiogenesis, cell growth, pattern formation, embryonic development, metabolic regulation, cell migration, neurotrophic effects, and tissue repair. FGF-basic is a non-glycosylated heparin binding g...
TMPJ-00037 FGF-2 Protein, Mouse, Recombinant

Fibroblast Growth Factor 2,bFGF,HBGF-2,Basic Fibroblast Grow...

Mouse E. coli
FGF basic is one of 22 mitogenic proteins of the FGF family, which show 35-60% amino acid conservation. Unlike other FGFs, FGF acidic and basic lack signal peptides and are secreted by an alternate pathway. The 17 kDa mouse sequence has 98% aa identity with rat, and 95% identity with human, bovine, and sheep FGF basic. Binding of FGF to heparin or cell surface HSPG is necessary for binding, dimerization and activation of tyrosine kinase FGF receptors. FGF basic binds other proteins, polysacchari...
TMPJ-01011 FGF-9 Protein, Mouse, Recombinant (His)

heparin-binding growth factor-9,GAF,HBGF-9,Glia-act...

Mouse E. coli
Fibroblast growth factor-9 (FGF-9) is an approximately 26 kDa secreted glycoprotein of the FGF family. Secreted mouse FGF-9 lacks the N-terminal 1-3 aa and shares >98% sequence identity with rat, human, equine, porcine and bovine FGF-9. FGF-9 plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. In the mouse embryo the location and timing of FGF-9 expression affects development of the skeleton, cerebellum, lungs, heart, v...
TMPH-03012 HBHA Protein, Mycobacterium tuberculosis, Recombinant (His & Myc)

Adhesin,Heparin-binding hemagglutinin,hbhA

Mycobacterium tuberculosis E. coli
Required for extrapulmonary dissemination. Mediates adherence to epithelial cells by binding to sulfated glycoconjugates present at the surface of these cells. HBHA Protein, Mycobacterium tuberculosis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.8 kDa and the accession number is P9WIP8.
TMPH-00378 Midkine Protein, Chicken, Recombinant (His & Myc)

Midkine,RIHB,Retinoic acid-induced heparin-binding ...

Chicken E. coli
Has mitogenic activity, and neurite extension activity for PC12 cells. Midkine Protein, Chicken, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 20.9 kDa and the accession number is P24052.
TMPJ-01051 Pleiotrophin/PTN Protein, Mouse, Recombinant (His)

HBGF-8,OSF-1,PTN,HBBM,Pleiotrophin,Heparin-binding ...

Mouse HEK293 Cells
Pleiotrophin (PTN) is a secreted, strongly heparinbinding, developmentally regulated cytokine. PTN is a highly conserved protein,Human, mouse, rat, canine, porcine, equine and bovine PTN share 98% aa sequence identity or greater. PTN and midkine share 50% amino acid (aa) sequence identity, share some functions, and constitute a family. During development, PTN is involved in development of brain, bone, and organs undergoing branching morphogenesis. PTN causes PTPRB dimerization and inactivates it...
TMPY-02246 HB-EGF Protein, Human, Recombinant

DTSF,DTR,HEGFL,heparin-binding EGF-like growth fact...

Human Baculovirus Insect Cells
Heparin-binding EGF-like growth factor (HBEGF), a member of the EGF family of growth factors, exerts its biological activity through activation of the EGFR and other ErbB receptors. Soluble mature HBEGF is proteolytically processed from a larger membrane-anchored precursor and is a potent mitogen and chemotactic factor for fibroblasts, smooth muscle cells but not endothelial cells. HBEGF activates two EGF receptor subtypes, HER1 and HER4, and binds to cell surface HSPG. The transmembrane form of...
TMPH-02654 FGF-5 Protein, Mouse, Recombinant (His)

Fgf5,Heparin-binding growth factor 5,Fibroblast gro...

Mouse E. coli
Plays an important role in the regulation of cell proliferation and cell differentiation. Required for normal regulation of the hair growth cycle. Functions as an inhibitor of hair elongation by promoting progression from anagen, the growth phase of the hair follicle, into catagen the apoptosis-induced regression phase. FGF-5 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 32.8 kDa and the accession number is P15656.
TMPH-01335 FGF-5 Protein, Human, Recombinant (GST & His & Myc)

Smag-82,FGF5,Fibroblast growth factor 5,Heparin-bin...

Human E. coli
Plays an important role in the regulation of cell proliferation and cell differentiation. Required for normal regulation of the hair growth cycle. Functions as an inhibitor of hair elongation by promoting progression from anagen, the growth phase of the hair follicle, into catagen the apoptosis-induced regression phase. FGF-5 Protein, Human, Recombinant (GST & His & Myc) is expressed in E. coli expression system with N-10xHis-GST and C-Myc tag. The predicted molecular weight is 62.4 kDa and the ...
TMPH-00369 FGF-2 Protein, Chicken, Recombinant (His & Myc)

Basic fibroblast growth factor,Fibroblast growth factor 2,

Chicken E. coli
Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. FGF-2 Protein, Chicken, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 23.8 kDa and the accession number is P48800.
TMPJ-01286 proHB-EGF Protein, Human, Recombinant (His)

heparin-binding EGF-like growth factor,HB-EGF,HEGFL...

Human HEK293 Cells
Heparin-binding EGF-like growth factor (HB-EGF) is a 12­16 kDa member of the epidermal growth factor (EGF) family. It possesses an EGF­like domain, and a heparin-binding motif. Mature HB­EGF is a soluble peptide that arises from proteolytic processing of the transmembrane form. Human HB­EGF shows 76% and 73% aa sequence identity with rat and mouse HB­EGF, respectively. It is required for normal cardiac valve formation and normal heart function, promotes smooth muscle cell proliferation. It may b...
TMPH-00368 FGF-2 Protein, Chicken, Recombinant (His)

Heparin-binding growth factor 2,FGF2,Fibroblast gro...

Chicken P. pastoris (Yeast)
Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. FGF-2 Protein, Chicken, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 18.3 kDa and the accession number is P48800.
TMPJ-00835 FGF-4 Protein, Mouse, Recombinant

HSTF1,HST-1,FGF4,FGF-4,HBGF-4,Fibroblast growth factor 4,HST...

Mouse E. coli
Fibroblast growth factor 4(FGF-4) is a heparin binding member of the FGF family. The human FGF4 cDNA encodes 206 amino acids (aa) with a 33 aa signal sequence and a 173 aa mature protein with an FGF homology domain that contains a heparin binding region near the C-terminus. Mature human FGF4 shares 91%, 82%, 94% and 91% aa identity with mouse, rat, canine and bovine FGF4, respectively. Human FGF-4 has been shown to exhibit cross species activity. Expression of FGF-4 and its receptors, FGF R1c, 2...
TMPH-03203 FGFb Protein, Rabbit, Recombinant (His & SUMO)

Basic fibroblast growth factor,Fibroblast growth factor 2,FG...

Rabbit E. coli
Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation. FGFb Protein, Rabbit, Recombinant (His & SUMO) is expressed in E. coli exp...
TMPH-03313 HMGB1 Protein, Rat, Recombinant (His)

High mobility group protein 1,Amphoterin,High mobility group...

Rat E. coli
HMGB1 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 30.8 kDa and the accession number is P63159.
TMPJ-00039 FGF-2 Protein, Human, Recombinant (K128N)

FGF2,bFGF,FGFB,Heparin-binding growth factor 2,HBGF...

Human E. coli
FGF-2 Protein, Human, Recombinant (K128N) is expressed in E. coli expression system. The predicted molecular weight is 17 KDa and the accession number is P09038-2.
TMPY-01254 Serpin D1 Protein, Mouse, Recombinant (His)

Serpind1,AI303446,AA985900,MGC107662,Hcf2,HCII,AI30344 6,ser...

Mouse HEK293 Cells
Serpin D1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 53.5 kDa and the accession number is P49182.
TMPJ-00040 FGF-2 Protein, Human,Recombinant (Q65I, C96S, N111G)

FGF-2,Fibroblast growth factor 2,Heparin-binding gr...

Human E. coli
FGF-2 Protein, Human,Recombinant (Q65I, C96S, N111G) is expressed in E. coli expression system. The predicted molecular weight is 16 KDa and the accession number is P09038-2.
TMPJ-00073 FGF-7/KGF Protein, Human, Recombinant

Fibroblast growth factor 7,成纤维细胞生长因子,FGF-7,Heparin-...

Human E. coli
Fibroblast growth factor 7 (FGF7) is a secreted protein which is mainly located in epithelial cells and belongs to the heparin-binding growth factors family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in...
TMPH-02502 LRPAP1 Protein, Mouse, Recombinant (His & Myc)

Heparin-binding protein 44,Alpha-2-macroglobulin re...

Mouse Baculovirus Insect Cells
Molecular chaperone for LDL receptor-related proteins that may regulate their ligand binding activity along the secretory pathway. LRPAP1 Protein, Mouse, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 18.2 kDa and the accession number is P55302.
TMPH-01221 GLCE Protein, Human, Recombinant (His)

Heparosan-N-sulfate-glucuronate 5-epimerase,D-glucuronyl C5-...

Human E. coli
Converts D-glucuronic acid residues adjacent to N-sulfate sugar residues to L-iduronic acid residues, both in maturing heparan sulfate (HS) and heparin chains. This is important for further modifications that determine the specificity of interactions between these glycosaminoglycans and proteins. GLCE Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 70.9 kDa and the accession number is O94923.
TMPY-00917 Serpin D1 Protein, Human, Recombinant (His)

serpin peptidase inhibitor, clade D (heparin cofact...

Human HEK293 Cells
Serpin D1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.4 kDa and the accession number is P05546.
TMPJ-00831 CCL3 Protein, Mouse, Recombinant (His)

LD78 α,MIP-1 α,MIP1-a,MIP-1 alpha,LD78 alpha,chemokine (C-C ...

Mouse E. coli
C-C Motif Chemokine 3 (MIP-1 alpha,CCL3 ) is a member of the beta or CC subfamily of chemokines and is closely related to CCL4/MIP-1 beta. CCL3 expression can be induced in a variety of hematopoietic cells, fibroblasts, smooth muscle cells, and epithelial cells. Mature mouse CCL3 shares 73%, 91%, and 82% amino acid sequence identity with human, rat, and cotton rat CCL3, respectively. CCL3 exerts its biological functions through interactions with CCR1, CCR3, and CCR5. It is cleared from the extra...
TMPJ-01430 NovoNectin Protein, Human, Recombinant

NovoNectin,Cold-insoluble globulin,FN,CIG,Fibronectin,Fibron...

Human E. coli
Fibronectin1(FN1) is a secreted protein and contains 12 fibronectin type-I domains,fibronectin type-II domains and 16 fibronectin type-III domains.Recombinant human fibronectin fragment, is a protein of ~63 kDa containing a central cell-binding domain, a high affinity heparin-binding domain II,and CS1 site within the alternatively spliced III CS region of human fibronectin. Cells bind to a VLA-4 ligand, a CS-I site, and a VLA-5 ligand, a cell attachment domain, and virus vectors binds to a hepar...
TMPJ-00865 VEGF121 Protein, Human, Recombinant (His)

VEGFA,VEGF-A,Vascular permeability factor,VPF,血管内皮生长因子,Vascu...

Human HEK293 Cells
Human VEGF121, also known as Vascular endothelial growth factor A, VEGFA, Vascular permeability factor, VPF and VEGF, is a homodimeric, heparin-binding glycoprotein which belongs to the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family. VEGF-A is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis, permeabilization of blood vessel...
TMPY-02907 FGF-19 Protein, Human, Recombinant

fibroblast growth factor 19,FGF19

Human E. coli
FGF19, also known as FGF-19, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF19 interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by KL, KLB and heparan sulfate glycosaminoglyca...
TMPY-00672 Azurocidin/CAP37 Protein, Human, Recombinant (His)

AZU,NAZC,azurocidin 1,hHBP,AZAMP,HUMAZUR,CAP37,HBP,AZU1

Human HEK293 Cells
Azurocidin (AZU1), also known as heparin-binding protein (HBP) or cationic antimicrobial protein 37 (CAP37), is an azurophil granule antibiotic protein, with monocyte chemotactic and antibacterial activity. The Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. Azurocidin is a member of the serine protease family that includes Cathepsin G, neutrophil elastase (NE), and proteinase 3 (PR3), however, Azurocidin is n...
TMPJ-01065 Noggin/NOG Protein, Mouse, Recombinant (His)

Nog,Noggin

Mouse HEK293 Cells
Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Mouse Noggin cDNA encodes a 232 amino acid (aa) residue precursor protein with 19 aa residue putative signal peptide that is cleaved to generate the 213 aa residue mature protein which is secreted as a homodimeric glycoprotein. Secreted Noggin probably remains close to the cell surface due to its binding of heparin-containing proteoglycans. Noggin binds some BMPs such as BMP4 with high affi...
TMPJ-00012 CXCL4 Protein, Human, Recombinant (His)

SCYB4,PF4,Iroplact,Platelet Factor 4,PF-4,Oncostatin-A,CXCL4...

Human HEK293 Cells
Human Chemokine (C-X-C motif) Ligand 4 (CXCL4) is expressed in megakaryocytes and stored in the alpha-granules of platelets. CXCL4 contains several heparin-binding sites at the C-terminal region and binds heparin with high affinity. The active CXCL4 protein is a tetramer. Human and mouse CXCL4 share 64% sequence identity. CXCL4 is chemotactic for neutrophils, fibroblasts and monocytes and plays a critical role in inflammation and wound repair. CXCL4 functions via a splice variant of the chemokin...
TMPY-00741 CXCL4 Protein, Human, Recombinant

PF-4,platelet factor 4,SCYB4,CXCL4

Human E. coli
Platelet factor 4 (PF4), also known as chemokine (C-X-C motif) ligand 4 (CXCL4), is a small cytokine belonging to the CXC chemokine family. CXCL4/PF4 is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils a...
TMPH-03121 CXCL4 Protein, Pig, Recombinant (His & Myc)

SCYB4,CXCL4,PF4,Platelet factor 4,PF-4,C-X-C motif chemokine...

Sus scrofa (Pig) E. coli
Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation. CXCL4 Protein, Pig, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 17.1 kDa and the accession number is P30034.
TMPH-02568 CTGF/CCN2 Protein, Mouse, Recombinant (GST)

betaIG-M2,Connective tissue growth factor,Protein FISP-12,Fi...

Mouse E. coli
Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.
TMPH-01550 Interferon kappa/IFNK Protein, Human, Recombinant (His & SUMO)

Interferon kappa,IFNK

Human E. coli
May play a role in the regulation of immune cell function. Cytokine that imparts cellular protection against viral infection in a species-specific manner. Activates the interferon-stimulated response element signaling pathway. It is able to directly modulate cytokine release from monocytes and dendritic cells. Binds heparin.
TMPJ-00897 TPSB2 Protein, Mouse, Recombinant (His)

Tryptase-2,Mast cell protease 6,Tryptase beta-2,Tryptase β-2...

Mouse HEK293 Cells
Tryptase beta-2(Tpsb2), also known as Mast cell protease 6(mMCP-6), belongs to the peptidase S1 family and Tryptase subfamily. Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. It plays a role in innate immunity. Tpsb2 can be detected primarily in skin during embryogenesis. Tpsb2 can not be detected at early embryonic stages but is abundantly expressed in later stages with a peak at E17.5-E18.5. Tryp...
TMPH-01559 IL-26 Protein, Human, Recombinant (His)

Protein AK155,Interleukin-26,IL26

Human P. pastoris (Yeast)
May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin. IL-26 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecula...
TMPK-00023 Midkine Protein, Human, Recombinant (His & Avi)

MDK,MEK,MK1,MKARAP,ARAP,MK,NEGF2

Human E. coli
Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue homeostasis and disease development. Midkine is abnormally expressed at high levels in various human malignancies and acts as a mediator for the acquisition of critical hallmarks of cancer, including cell growth, survival, metastasis, migration, and angiogenesis. Midkine Protein, Hu...
TMPK-00024 Midkine Protein, Human, Recombinant (His & Avi), Biotinylated

MK1,MK,MDK,NEGF2,MKARAP,MEK,ARAP

Human E. coli
Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue homeostasis and disease development. Midkine is abnormally expressed at high levels in various human malignancies and acts as a mediator for the acquisition of critical hallmarks of cancer, including cell growth, survival, metastasis, migration, and angiogenesis. Midkine Protein, Hu...
TMPY-02172 Midkine Protein, Human, Recombinant

midkine (neurite growth-promoting factor 2),NEGF2,MK,ARAP

Human Baculovirus Insect Cells
Midkine (MK or MDK) also known as neurite growth-promoting factor 2 (NEGF2) is a basic heparin-binding growth factor of low molecular weight, and forms a family with pleiotrophin. Midkine is a retinoic acid-responsive, heparin-binding growth factor expressed in various cell types during embryogenesis. It promotes angiogenesis, cell growth, and cell migration. Midkine is also expressed in several carcinomas, suggesting that it may play a role in tumorigenesis, perhaps through its effects on angio...
TMPH-01069 CTGF/CCN2 Protein, Human, Recombinant (His)

Hypertrophic chondrocyte-specific protein 24,CCN family memb...

Human E. coli
Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. CTGF/CCN2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 15.1 kDa and...
TMPJ-01002 SGSH Protein, Human, Recombinant (His)

SGSH,N-Sulphoglucosamine Sulphohydrolase,Sulfoglucosamine Su...

Human HEK293 Cells
N-Sulphoglucosamine Sulphohydrolase (SGSH) is an important member of the sulfatase family which is involved in the degradation of heparin sulfate. SGSH binds one calcium ion per subunit as a cofactor. SGSH catalyzes N-sulfo-D-glucosamine and H2O to D-glucosamine and sulfate. SGSH deficiency is result in mucopolysaccharidosis type 3A (MPS3A), a recessive lysosomal storage disease characterized by neurological dysfunction but relatively mild somatic manifestations.
TMPJ-00096 FGF-17 Protein, Human, Recombinant (His)

Fibroblast Growth Factor 17,FGF17,FGF-17

Human HEK293 Cells
Fibroblast Growth Factor 17 (FGF17) is a member of the heparin-binding growth factors family that is prominently expressed in the cerebellum and cortex. Proteins of this family possess broad mitogenic and cell survival activities and they are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth, and invasion. FGF17 plays an important role in the regulation of embryonic development and it acts as signaling molecule i...
TMPJ-00542 TPSB2 Protein, Human, Recombinant (His)

Tryptase-2,Tryptase Beta-2,TPS2,TPSB2,Tryptase II,Tryptase β...

Human HEK293 Cells
Tryptases are Trypsin-like Serine Proteases. β-Tryptases are the main isoenzymes in mast cells. Βtryptases form active tetramers with heparin proteoglycan. In the tetramer, the unique arrangement of the active sites facing a narrow central pore, β-Tryptases are resistant to macromolecule protease inhibitors . When mast cells are activated, β-Tryptases are released and participate in provoking inflammatory conditions . β-Tryptases have been implicated as mediators in the pathogenesis of asthma an...
TMPK-00812 Midkine Protein, Mouse, Recombinant (His)

MK1,ARAP,MKARAP,MEK,MK,NEGF2,MDK

Mouse E. coli
Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue homeostasis and disease development. Midkine is abnormally expressed at high levels in various human malignancies and acts as a mediator for the acquisition of critical hallmarks of cancer, including cell growth, survival, metastasis, migration, and angiogenesis. Midkine Protein, Mo...
TMPH-01560 IL-26 Protein, Human, Recombinant (His & Trx)

Interleukin-26,Protein AK155,IL26

Human E. coli
May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin. IL-26 Protein, Human, Recombinant (His & Trx) is expressed in E. coli expression system with N-6xHis-T...
TMPJ-01163 CTGF/CCN2 Protein, Human, Recombinant (HEK293, His)

CTGF,Connective tissue growth factor

Human HEK293 Cells
Connective Tissue Growth Factor (CTGF), also known as CCN2, is a member of the CCN (CYR61/CTGF/NOV) family of secreted matricellular proteins. Like other CCN proteins, mature human CTGF consists of IGF-binding protein domain, a vWF-C domain, a TSP-1 domain, and a cysteine knot heparin-binding domain. CTGF has various biological functions, including cell adhesion, migration, proliferation, differentiation, and ECM production, and participates in the development of many organs under normal physio...
TMPH-00813 Hepatitis E virus genotype 1 (HEV-1) Secreted protein ORF2 (His)

Protein ORF2,Pro-secreted protein ORF2

HEV-1 Baculovirus Insect Cells
Plays a role in the inhibition of host antibody-mediated neutralization without blocking viral cell entry.; Forms an icosahedral capsid with a T=1 symmetry and a 34 nm diameter. The capsid is composed of 60 copies linked to each other. Binds to the 5' end of the genomic RNA to mediate genome encapsidation. Binds to heparin surface proteoglycans (HSPGs) to mediate viral entry. Additionally, the interactions with host ASGR1 and ASGR2 facilitate viral infection of hepatocytes. Hepatitis E virus gen...
TMPJ-00931 Serpin A4 Protein, Human, Recombinant (His)

Kallistatin,Peptidase Inhibitor 4,KST,Kallikrein Inhibitor,S...

Human HEK293 Cells
Serpin Peptidase Inhibitor, Clade A (α-1 Antiproteinase, Antitrypsin), Member 4 (Serpin A4) is a member of the Serpin family. Serpin A4 exists as a monomer and some homodimers. Serpin A4 is expressed by the liver and secreted in plasma. Serpin A4 is a regulator of vascular homeostasis capable of controlling a wide spectrum of biological actions in the cardiovascular and renal systems. It can inhibit intracellular reactive oxygen species formation in cultured cardiac and renal cells. In addition,...
TMPJ-01004 HDGF Protein, Human, Recombinant (His)

HDGF,Hepatoma-Derived Growth Factor,HMG1L2,High Mobility Gro...

Human E. coli
Hepatoma-Derived Growth Factor is a original member of the HDGF family. HDGF is a cytoplasmic protein and contains one PWWP domain. HDGF expression levels are high in the nucleus and cytoplasm of smooth muscle and endothelial cells. HDGF has proliferative, angiogenic and neurotrophic activity. HDGF was initially characterized as a secreted mitogen from the Huh-7 human hepatoma cell line. As a heparin-binding protein, which is highly expressed in tumor cells where it stimulates proliferation. HDG...
TMPJ-00523 SAA2 Protein, Human, Recombinant (His)

SAA2,SAA,Serum Amyloid A2

Human E. coli
Serum amyloid A-2 protein (SAA2) belongs to the SAA family. It expressed by the liver and secreted in plasma. SAA2 functions as major acute phase reactant and could works as apolipoprotein of the HDL complex. Increased levels of A-SAA in serum are indicative of inflammatory disease. When highly expressed, SAA can displace ApoA1 as the major apolipoprotein in HDL complexes, weakening the function of HDL as a reverse (lipid clearing) cholesterol transporter. A highly charged region of SAA2 and SAA...
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重组蛋白

FGF-9 Protein, Human, Recombinant
Cat.No: TMPJ-00090
Species: Human
Expression System: E. coli
FGF-2 Protein, Rat, Recombinant
Cat.No: TMPJ-00842
Species: Rat
Expression System: E. coli
FGF-2 Protein, Mouse, Recombinant
Cat.No: TMPJ-00037
Species: Mouse
Expression System: E. coli
FGF-9 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01011
Species: Mouse
Expression System: E. coli
HBHA Protein, Mycobacterium tuberculosis, Recombinant (His & Myc)
Cat.No: TMPH-03012
Species: Mycobacterium tuberculosis
Expression System: E. coli
Midkine Protein, Chicken, Recombinant (His & Myc)
Cat.No: TMPH-00378
Species: Chicken
Expression System: E. coli
Pleiotrophin/PTN Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01051
Species: Mouse
Expression System: HEK293 Cells
HB-EGF Protein, Human, Recombinant
Cat.No: TMPY-02246
Species: Human
Expression System: Baculovirus Insect Cells
FGF-5 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02654
Species: Mouse
Expression System: E. coli
FGF-5 Protein, Human, Recombinant (GST & His & Myc)
Cat.No: TMPH-01335
Species: Human
Expression System: E. coli
FGF-2 Protein, Chicken, Recombinant (His & Myc)
Cat.No: TMPH-00369
Species: Chicken
Expression System: E. coli
proHB-EGF Protein, Human, Recombinant (His)
Cat.No: TMPJ-01286
Species: Human
Expression System: HEK293 Cells
FGF-2 Protein, Chicken, Recombinant (His)
Cat.No: TMPH-00368
Species: Chicken
Expression System: P. pastoris (Yeast)
FGF-4 Protein, Mouse, Recombinant
Cat.No: TMPJ-00835
Species: Mouse
Expression System: E. coli
FGFb Protein, Rabbit, Recombinant (His & SUMO)
Cat.No: TMPH-03203
Species: Rabbit
Expression System: E. coli
HMGB1 Protein, Rat, Recombinant (His)
Cat.No: TMPH-03313
Species: Rat
Expression System: E. coli
FGF-2 Protein, Human, Recombinant (K128N)
Cat.No: TMPJ-00039
Species: Human
Expression System: E. coli
Serpin D1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01254
Species: Mouse
Expression System: HEK293 Cells
FGF-2 Protein, Human,Recombinant (Q65I, C96S, N111G)
Cat.No: TMPJ-00040
Species: Human
Expression System: E. coli
FGF-7/KGF Protein, Human, Recombinant
Cat.No: TMPJ-00073
Species: Human
Expression System: E. coli
LRPAP1 Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02502
Species: Mouse
Expression System: Baculovirus Insect Cells
GLCE Protein, Human, Recombinant (His)
Cat.No: TMPH-01221
Species: Human
Expression System: E. coli
Serpin D1 Protein, Human, Recombinant (His)
Cat.No: TMPY-00917
Species: Human
Expression System: HEK293 Cells
CCL3 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00831
Species: Mouse
Expression System: E. coli
NovoNectin Protein, Human, Recombinant
Cat.No: TMPJ-01430
Species: Human
Expression System: E. coli
VEGF121 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00865
Species: Human
Expression System: HEK293 Cells
FGF-19 Protein, Human, Recombinant
Cat.No: TMPY-02907
Species: Human
Expression System: E. coli
Azurocidin/CAP37 Protein, Human, Recombinant (His)
Cat.No: TMPY-00672
Species: Human
Expression System: HEK293 Cells
Noggin/NOG Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01065
Species: Mouse
Expression System: HEK293 Cells
CXCL4 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00012
Species: Human
Expression System: HEK293 Cells
CXCL4 Protein, Human, Recombinant
Cat.No: TMPY-00741
Species: Human
Expression System: E. coli
CXCL4 Protein, Pig, Recombinant (His & Myc)
Cat.No: TMPH-03121
Species: Sus scrofa (Pig)
Expression System: E. coli
CTGF/CCN2 Protein, Mouse, Recombinant (GST)
Cat.No: TMPH-02568
Species: Mouse
Expression System: E. coli
Interferon kappa/IFNK Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01550
Species: Human
Expression System: E. coli
TPSB2 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00897
Species: Mouse
Expression System: HEK293 Cells
IL-26 Protein, Human, Recombinant (His)
Cat.No: TMPH-01559
Species: Human
Expression System: P. pastoris (Yeast)
Midkine Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00023
Species: Human
Expression System: E. coli
Midkine Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00024
Species: Human
Expression System: E. coli
Midkine Protein, Human, Recombinant
Cat.No: TMPY-02172
Species: Human
Expression System: Baculovirus Insect Cells
CTGF/CCN2 Protein, Human, Recombinant (His)
Cat.No: TMPH-01069
Species: Human
Expression System: E. coli
SGSH Protein, Human, Recombinant (His)
Cat.No: TMPJ-01002
Species: Human
Expression System: HEK293 Cells
FGF-17 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00096
Species: Human
Expression System: HEK293 Cells
TPSB2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00542
Species: Human
Expression System: HEK293 Cells
Midkine Protein, Mouse, Recombinant (His)
Cat.No: TMPK-00812
Species: Mouse
Expression System: E. coli
IL-26 Protein, Human, Recombinant (His & Trx)
Cat.No: TMPH-01560
Species: Human
Expression System: E. coli
CTGF/CCN2 Protein, Human, Recombinant (HEK293, His)
Cat.No: TMPJ-01163
Species: Human
Expression System: HEK293 Cells
Hepatitis E virus genotype 1 (HEV-1) Secreted protein ORF2 (His)
Cat.No: TMPH-00813
Species: HEV-1
Expression System: Baculovirus Insect Cells
Serpin A4 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00931
Species: Human
Expression System: HEK293 Cells
HDGF Protein, Human, Recombinant (His)
Cat.No: TMPJ-01004
Species: Human
Expression System: E. coli
SAA2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00523
Species: Human
Expression System: E. coli
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Cat. No. Product Name Target Signaling Pathways
TMIJ-0384 L-Cysteine-d3

L-Cysteine-d3 是 L-Cysteine 的氘代化合物。L-Cysteine 的 CAS 号为 52-90-4。L-Cysteine 是人体非必需的含硫氨基酸。L-Cysteine 对蛋白质合成、解毒和多种代谢功能很重要。L-Cysteine 存在于指甲、皮肤和头发的主要蛋白质-角蛋白中,对胶原蛋白的生成、皮肤弹性和质地都很重要。L-Cysteine 是抗氧化剂谷胱甘肽的一种成分,在辅酶A、肝素和生物素等基本生化物质的代谢中起着重要作用,也是氨基酸牛磺酸的制造所必需的。

同位素标记化合物

L-Cysteine-d3
Cat.No: TMIJ-0384
Synonym:
Target:
TargetMol Loading
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