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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T2029 |
Bohemine
|
ERK; CDK | Cell Cycle/Checkpoint; MAPK |
Bohemine 是一种合成的选择性CDK 抑制剂,是嘌呤类似物,具有抗癌活性。它对Cdk2/cyclin E、Cdk2/cyclin A 和Cdk9/cyclin T1的IC50分别为 4.6 μM、83 μM 和 2.7 μM。 | |||
T22873 |
Ischemin sodium salt
|
Others | Others |
CBP bromodomain inhibitor |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T5515 |
Hemin
氯化血红素,Hemin chloride |
Mitophagy; Ferroptosis; Autophagy | Apoptosis; Autophagy |
Hemin (Hemin chloride) 是一种含有氯的含铁卟啉,一种血红素加氧酶 (HO)-1 诱导剂。Hemin 对卟啉病具有治疗活性,可以减少患者的血红素缺乏,从而通过生物化学反馈抑制 δ-氨基乙酰丙酸合成酶的活性。 | |||
T82256 |
Grosshemin
Grosshemine |
||
Grosshemin (Grosshemine),Centaurea scabiosa 种群中的天然化合物。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-03138 |
GST Protein, Plasmodium falciparum, Recombinant (His)
|
Plasmodium falciparum | P. pastoris (Yeast) |
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. May also function as a storage protein or ligandin for parasitotoxic ferriprotoporphyrin IX (hemin). GST Protein, Plasmodium falciparum, Recombinant (His) is expressed in yeast with N-10xHis tag. The predicted molecular weight is 27.3 kDa and the accession number is Q8MU52. |