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Search Results for " heme synthase "

Targets Recommended: Others

抑制剂 & 化合物

天然产物

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T83663	Mn(III) Protoporphyrin IX Chloride Manganese(III) Protoporphyrin IX Chloride	Others	Others
	Mn(III) protoporphyrin IX chloride是一种金属卟啉，当浓度为10 µM时，能在鸡胚肝细胞中诱导δ-氨基酮戊二酸合成酶和血红素加氧酶(HO)基因的mRNA表达，这些酶分别催化血红素生物合成和降解的限速步骤。Mn(III) protoporphyrin IX chloride含纳米仿生物已被用于体外纤维蛋白凝块的磁共振成像(MRI)研究。此外，它还被用于Mn(III) protoporphyrin IX-6(7)-甘氨酰-甘氨酰-L-组氨酸甲酯(MnGGH)的合成，MnGGH是一种具有微过氧化物酶活性的金属卟啉衍生物。
T38980	Mg(II) protoporphyrin IX	Others	Others
	Mg(II) protoporphyrin IX is a crucial compound in the synthesis of chlorophyll in Chlorella. It also serves as a negative regulator of nuclear photosynthetic gene expression. Additionally, Mg(II) protoporphyrin IX is employed as a valuable research tool for investigating the signaling molecule involved in plastid-to-nucleus communication.
T38935	Cu(II) protoporphyrin IX	Others	Others
	Cu (II) Protoporphyrin IX functions as a negative control for Zn (II) Protoporphyrin, a heme oxygenase inhibitor. Heme oxygenase is involved in tumor cell resistance to chemotherapy and the regulation of free radical formation, inflammation, and vascular repair.
T39603	Mn(II) protoporphyrin IX	Others	Others
	Mn(II) protoporphyrin IX is a potent intravenous paramagnetic magnetic resonance contrast agent, known for its strong paramagnetic properties.

化合物

Mn(III) Protoporphyrin IX Chloride

Cat.No: T83663

Synonym: Manganese(III) Protoporphyrin IX Chloride

Target: Others

Mg(II) protoporphyrin IX

Cat.No: T38980

Synonym:

Target: Others

Cu(II) protoporphyrin IX

Cat.No: T38935

Synonym:

Target: Others

Mn(II) protoporphyrin IX

Cat.No: T39603

Synonym:

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T2915	Bardoxolone RTA 401,齐墩果烷三萜化合物,CDDO	Others; Nrf2	Immunology/Inflammation; Others
	Bardoxolone (CDDO) 是新型核调节因子激活剂。
T1192	Protoporphyrin IX PPIX,原卟啉,原卟啉IX	Others; Endogenous Metabolite	Metabolism; Others
	Protoporphyrin IX (PPIX) 是一种四吡咯，是血红素、细胞色素 c 和叶绿素的代谢前体。

天然产物

Bardoxolone

Cat.No: T2915

Synonym: RTA 401,齐墩果烷三萜化合物,CDDO

Target: Others, Nrf2

Protoporphyrin IX

Cat.No: T1192

Synonym: PPIX,原卟啉,原卟啉IX

Target: Others, Endogenous Metabolite

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-00265	Ferrochelatase, mitochondrial Protein, Bovine, Recombinant (His & Myc & SUMO) Ferrochelatase, mitochondrial,Protoheme ferro-lyase...	Bovine	E. coli
	Catalyzes the ferrous insertion into protoporphyrin IX. Ferrochelatase, mitochondrial Protein, Bovine, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Mycd tag. The predicted molecular weight is 58.1 kDa and the accession number is P22600.
TMPH-01332	Ferrochelatase Protein, Human, Recombinant (His & Myc) Ferrochelatase, mitochondrial,Heme synthase	Human	E. coli
	Catalyzes the ferrous insertion into protoporphyrin IX. Ferrochelatase Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 49.6 kDa and the accession number is P22830.
TMPJ-00830	UROIIIS Protein, Human, Recombinant (His) Hydroxymethylbilane Hydrolyase [Cyclizing],Uroporphyrinogen-...	Human	E. coli
	Uroporphyrinogen-III Synthase is an enzyme which belongs to the uroporphyrinogen-III synthase family. Uroporphyrinogen-III Synthase is ubiquitous and it is involved in Porphyrin metabolism. Porphyrins act as cofactors for a multitude of enzymes that perform a variety of processes within the cell such as Methionine synthesis (Vitamin B12) or oxygen transport (Heme). Uroporphyrinogen-III Synthase can catalyze cyclization of the linear Tetrapyrrole, Hydroxymethylbilane, to the Macrocyclic Uroporphy...
TMPH-02617	COX5A Protein, Mouse, Recombinant (His & SUMO) Cytochrome c oxidase subunit 5A, mitochondrial,COX5A,Cytochr...	Mouse	E. coli
	Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over t...