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Search Results for " hela "

Targets Recommended: Glucokinase

180

抑制剂 & 化合物

99

天然产物

9

重组蛋白

1

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T23552	YZ9	Glucokinase	Metabolism
	Y29 是 PFKFB3抑制剂，IC50为 0.183 µM。Y29是 Fru-6-P 的竞争性抑制剂，Ki 为 0.094 µM。Y29 抑制 HeLa 细胞生长，GI50为 2.7 µM。
T21992	Vacuolin-1	PI3K; Autophagy	Autophagy; PI3K/Akt/mTOR signaling
	Vacuolin-1 是一种细胞渗透性抑制剂，可抑制 Ca2+ 依赖性溶酶体与细胞膜的融合。它通过抑制溶酶体内容物的释放起作用。它是一种有效的选择性 PIKfyve 抑制剂，通过损害溶酶体成熟来抑制晚期自噬。
T8513	Spastazoline	Others	Others
	Spastazoline 是spastin(一种微管切断AAA 蛋白) 的选择性抑制剂，对人 spastin 的IC50值为 99 nM。它不能影响重组人 VPS4 的 ATPase 活性。
T0855	(R)-Naproxen	COX	Immunology/Inflammation; Neuroscience
	(R)-Naproxen 是一种抗炎剂，具有解热和镇痛作用。酸及其钠盐都用于治疗急性痛风或痛经、肌肉骨骼疾病、类风湿性关节炎和其他风湿病。
T11563	Histone Acetyltransferase Inhibitor II	Epigenetic Reader Domain; Histone Acetyltransferase	Chromatin/Epigenetic
	Histone Acetyltransferase Inhibitor II 是一种选择性的细胞渗透性 p300 组蛋白乙酰转移酶抑制剂，IC50值为 5 µM。它在哺乳动物细胞中具有抗乙酰化酶活性，可用于癌症研究。
T9119	SU0268	Others	Others
	SU0268 是有效的 8-8-氧鸟嘌呤 DNA 糖基化酶1的选择性抑制剂，具有调控铜绿假单胞杆菌感染免疫反应的能力。
T23372	SMIFH2	Others	Others
	SMIFH2 是formin 特异性抑制剂。它利用 Formins 阻碍肌动蛋白聚合，影响肌动蛋白细胞骨架。
T6421	BRD73954	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	BRD73954 是一种有效且特异性的 HDAC 抑制剂，对 HDAC6 和 HDAC8 的 IC50 分别为 36 nM 和 120 nM。
T11553	Heptamidine dimethanesulfonate SBi4211 dimethanesulfonate	Others	Others
	Heptamidine dimethanesulfonate (SBi4211 dimethanesulfonate) 是一种与喷他脒有关的、强效的钙结合蛋白 S100B 的抑制剂 (Kd=6.9 μM)，选择性地杀死表达 S100B 的黑素瘤细胞。它是有效的强直性肌营养不良 (DM) 研究工具。
T34603	L-Selenocystine L-Selenocystine,L-硒代胱胺基乙酸	Others	Others
	L-Selenocystine (L-Selenocystine) 可用作生物活性硒醇化合物的组成部分。
T50005	Sertaconazole	Antifungal	Microbiology/Virology
	Sertaconazole 是一种广谱抗真菌药。
T12006	Metarrestin ML246	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Metarrestin (ML246) 是一种口服有效的选择性核仁周区室 (PNC) 抑制剂，可有效抑制转移。Metarrestin 破坏核仁结构并抑制 RNA 聚合酶 (Pol) I 转录，部分是通过与翻译延伸因子 eEF1A2 的相互作用。
T12579	RAMB4 PTP1B-IN-9	Proteasome	Proteases/Proteasome; Ubiquitination
	RAMB4 (PTP1B-IN-9) 是一种泛素-蛋白酶体系统(UPS)应激源，是通过抑制 20S 蛋白酶体催化活性物质上游泛素介导的蛋白质降解而产生。它能够在不影响 20S 蛋白酶体催化活性的情况下触发泛素蛋白酶体系统 (UPS) 应激反应。
T5399	GeA-69	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	GeA-69 是一种选择性变构 PARP14 大结构域 2 (MD2) 抑制剂，Kd 值为 2.1 µM。
T3076	GLPG0634 analog GLPG0634 analogue	Tyrosine Kinases; JAK	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
	GLPG0634 analog (GLPG0634 analogue) 是一种 JAK 广谱性抑制剂，对 JAK1/JAK2/JAK3 的 IC50值为 50 到 200 nM 之间。
T9024	OUL35 NSC39047	Others; PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair; Others
	OUL35 (NSC-39047) 是一种选择性 PARP-10 抑制剂和小分子 ARTD10 抑制剂，其 IC50值为 329 nM。
T9350	IMP-1088	Others; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others
	IMP-1088 是一种人N-肉豆蔻酰基转移酶NMT1和NMT2双重抑制剂，对 HsNMT1 和 HsNMT2 的IC50小于1 nM，对 HsNMT1 的Kd 小于210 pM。它有保护宿主细胞免受病毒感染的细胞毒作用，通过阻断鼻病毒的 N-肉豆蔻酰化蛋白来阻断鼻病毒的复制。
T9098	DMG-PEG 2000 DMG-PEG2000	Others	Others
	DMG-PEG 2000 (DMG-PEG2000) 可用于脂质纳米颗粒制备，用于口服质粒 DNA 的体内传递途径，提高纳米颗粒的黏液渗透性和传递效率。它也可用于 siRNA 转染的脂质体的制备，能够提高转染效率。
T0711	Niclosamide BAY2353,Niclocide,氯硝柳胺	Antibiotic; STAT; Parasite	JAK/STAT signaling; Microbiology/Virology; Stem Cells
	Niclosamide (Niclocide) 是一种口服生物可利用的氯化水杨酰苯胺。它通过抑制 DNA 复制，具有驱虫和潜在的抗肿瘤活性。
T3103	L67 DNA Ligase Inhibitor	DNA; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	L67 (DNA Ligase Inhibitor) 是一种竞争性人类 DNA 连接酶抑制剂，抑制 DNA 连接酶 I 和 III，IC50为10μM。
T2617	SNS-314 Mesylate SNS-314	Aurora Kinase	Cell Cycle/Checkpoint; Chromatin/Epigenetic
	SNS-314 Mesylate (SNS-314) 是一种有效且特异性的极光激酶抑制剂，对极光激酶 A、B、C 的 IC50值分别为 9，31 和 3 nM。
T9079	Apostatin-1 Apt-1	Others	Others
	Apostatin-1 (Apt-1) 是一种新型 TRADD 抑制剂。 Apostatin-1 可以与 TRADD 的 N 末端 TRAF2 结合域上的口袋结合。
T7020	Z-VAD-FMK Z-VAD(OH)-FMK,Caspase Inhibitor VI,Z-VAD	Caspase	Apoptosis; Proteases/Proteasome
	Z-VAD-FMK (Caspase Inhibitor VI) 是一种 caspase 的广谱抑制剂。Z-VAD-FMK 可以与活化的 caspase 结合，从而抑制细胞凋亡。Z-VAD-FMK即使在高达 440μM 的浓度下也不会抑制 UCHL1 的活性。
T4327	Prexasertib dihydrochloride LY2606368 (dihydrochloride),Prexasertib HCl,LY2606368	Apoptosis; Chk; S6 Kinase	Apoptosis; Cell Cycle/Checkpoint; MAPK; PI3K/Akt/mTOR signaling
	Prexasertib dihydrochloride (LY2606368) 是一种选择性的，ATP 竞争性的细胞周期检测点激酶 1 抑制剂，Ki 为 0.9 nM，IC50为 <1 nM。它抑制 CHK2(IC50=8 nM) 和 RSK1 (IC50=9 nM)。它引起双链 DNA 断裂和复制突变，导致细胞凋亡，有抗肿瘤活性。
T0455	Clozapine 氯氮平,HF 1854,LX 100-129	Dopamine Receptor; Adrenergic Receptor; AChR	GPCR/G Protein; Neuroscience
	Clozapine (HF 1854) 是一种三环二苯二氮卓类药物，属于非典型抗精神病药物。它结合几种类型的中枢神经系统受体，并显示出独特的药理学特征。它是一种血清素拮抗剂，与 5-HT 2A/2C 受体亚型具有强结合力。它还对几种多巴胺能受体表现出很强的亲和力，但对多巴胺 D2 受体仅表现出较弱的拮抗作用，这种受体通常被认为可调节精神抑制活性。
T6665	Sertaconazole nitrate FI-7045,Ginedermofix,FI7056,Ertaczo,硝酸舍他康唑	Antibiotic; Antifungal	Microbiology/Virology
	Sertaconazole nitrate (FI-7045) 是一种局部广谱抗真菌药，可用于治疗浅表皮肤和粘膜感染。
T15396	GN44028 N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,4-dihydroindeno[1,2-c]pyrazol-3-amine	HIF	Angiogenesis; Chromatin/Epigenetic
	GN44028 (N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,4-dihydroindeno[1,2-c]pyrazol-3-amine) 是缺氧诱导因子(HIF)-1的有效抑制剂，其 IC50=14 nM。它可以抑制低氧诱导的 HIF-1α 的转录特性，但不抑制 HIF-1α mRNA 的表达，HIF-1α 蛋白的累积或HIF-1α/HIF-1β 的异缘二聚化。
T4310	Prexasertib 5-[[5-[2-(3-氨基丙氧基)-6-甲氧基苯基]-1H-吡唑-3-基]氨基]-2-吡嗪甲腈,LY2606368	Apoptosis; Chk	Apoptosis; Cell Cycle/Checkpoint
	Prexasertib (LY2606368) 是一种具有潜在抗肿瘤活性的检查点激酶 1 抑制剂。它可引起双链 DNA 断裂和复制突变，导致细胞凋亡。
T13639	Deferasirox (Fe3+ chelate)	Apoptosis	Apoptosis
	Deferasirox (Fe3+ chelate) 是一种可口服的铁螯合剂，具有潜在的抗癌活性，抑制 MCL-1 的抗凋亡活性，可用于研究铁超负荷。
T81479	Phytochelatin 3 PC 3
	Phytochelatin 3 (PC 3)是一种具有金属螯合能力的小型肽，主要用途为螯合重金属离子。
T30873	Chelator 1a Chelator1a,Chelator-1a	Antifungal	Microbiology/Virology
	Chelator 1a 具有抗真菌活性，抑制曲霉菌和念珠菌，可用于研究真菌感染和癌症。
T81475	Phytochelatin 5 PC 5
	Phytochelatin 5为植物合成的金属结合化合物，具有可能降低如镉等膳食有毒金属的生物利用度。
T81472	Phytochelatin 6 TFA PC 6 TFA
	Phytochelatin 6 TFA为植物合成的金属结合化合物，具有降低如镉等膳食有毒金属的生物可利用性的潜能。
T81477	Phytochelatin 4 PC 4
	Phytochelatin 4 (PC 4)为植物体内富含Cys的小分子短肽，其结构特征为含有γ-Glu-Cys基序。
T81474	Phytochelatin 5 TFA PC 5 TFA
	Phytochelatin 5 TFA为植物合成的金属结合化合物，有潜在降低食物中有毒金属（例如镉）生物可利用性的作用。
T81480	Phytochelatin 2 (PC2) (TFA)
	Phytochelatin 2 (PC2) TFA是一种具有植物螯合素性质的重要肽类，能有效地与重金属离子形成稳定的螯合物，起到防护作用，避免金属离子的毒性影响，并促进体内金属离子的平衡稳定。
T81478	Phytochelatin 3 TFA PC 3 TFA
	Phytochelatin 3 (PC 3) TFA，一小分子螯合肽，专用于重金属离子螯合。
T41109	Phytochelatin 2 (PC2)
	Phytochelatin 2, a short plant peptide, serves as an essential metal-binding compound. Phytochelatins are a diverse group of plant compounds that play a crucial role in chelating metals, safeguarding against metal toxicity, and maintaining metal homeostasis.
T81476	Phytochelatin 4 TFA PC 4 TFA
	Phytochelatin 4 (PC 4) TFA，一种在植物中发现的短肽，富含 Cys，且具有 γ-Glu-Cys 基序。
T81473	Phytochelatin 6 PC 6
	Phytochelatin 6是一种植物所产生的金属结合化合物，其可能降低（如镉）等膳食有毒金属的生物利用度。
T124710	Trachelanthamidine	Others	Others
	Trachelanthamidine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T124710。
T8517	Belinostat PX105684,PXD101,贝利司他,PXD-101	HDAC; Autophagy	Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair
	Belinostat (PXD101) 是一种异羟肟酸型组蛋白脱乙酰酶抑制剂，具有抗肿瘤活性，在 HeLa 细胞提取物中的IC50为 27 nM。
T11657	INH154	Others	Others
	INH154 是一种高效的 Nek2 和 Hec1 结合抑制剂，能够抑制 Hela 细胞(IC50:200 nM)、 MB468 细胞(IC50:120 nM)。
T7181	IDO-IN-1 4-氨基-N-(3-溴-4-氟苯基)-N'-羟基-1,2,5-恶二唑-3-甲脒	Indoleamine 2,3-Dioxygenase (IDO)	Metabolism
	IDO-IN-1 是吲哚胺-2,3-双加氧酶抑制剂，IC50=59 nM。
T77771	Compound 10w	Others	Others
	Compound 10w，一种取代吡唑并[1,5-a]嘧啶酰胺化合物，是一种ZSTK474 类似物，对 HeLa细胞显示出抗癌活性。
T25214	CCR-11 CCR11,CCR 11	Antibiotic	Microbiology/Virology
	CCR-11 是一种具有抗菌活性的绕丹宁衍生物。 CCR-11 可以抑制 B. subtilis细胞和 HeLa 细胞增殖。 CCR-11 通过抑制 FtsZ 的组装和 GTPase 活性来抑制细菌增殖和细菌胞质分裂。 CCR-11 具有潜在的抗肿瘤活性，可用于研究乳腺癌和小儿骨髓增生异常。
T5342	IWP-O1	Wnt/beta-catenin; Porcupine	Cytoskeletal Signaling; Stem Cells
	IWP-O1 是 Porcn 抑制剂，在 L-Wnt-STF 细胞中的 EC50值为 80 pM。它能够抑制 Wnt 蛋白分泌，可以抑制 HeLa 细胞中 Dvl2/3 和 LRP6 磷酸化。
T25969	Poloxin-2 Poloxin2,Poloxin 2	PLK	Cell Cycle/Checkpoint
	Poloxin-2 是一种具有有效性和选择性的 Plk1 PBD 抑制剂，具有抗肿瘤活性，可降低HeLa细胞中Plk1的蛋白水平。
T8903	Retro-2 Retro 2,2-{[(5-methyl-2-thienyl)methylene]amino}	Others; Virus Protease; Parasite; Autophagy	Autophagy; Microbiology/Virology; Others
	Retro-2 (2-{[(5-methyl-2-thienyl)methylene]amino}) 是一种植物毒素蓖麻毒素抑制剂，它保护 HeLa 细胞免受蓖麻毒素、Stx1 和 Stx2 的侵害，选择性地阻断早期内体蛋白质-高尔基体界面处的逆行毒素运输。
T8623	TMIFRY8XAG 4,4,-二(4-氟苯)氯丁烷,1,1'-(4-CHLOROBUTYLIDENE)BIS(4-FLUOROBENZENE),4-oxo-1,4-dihydroquinoline-2-carboxylic acid	Others	Others
	TMIFRY8XAG (4-oxo-1,4-dihydroquinoline-2-carboxylic acid) 是 Zerumbone 的衍生物，对 HeLa 癌细胞具有潜在的抗肿瘤作用。

化合物

Cat.No: T23552

Target: Glucokinase

Cat.No: T21992

Target: PI3K, Autophagy

Cat.No: T8513

Target: Others

Cat.No: T0855

Target: COX

Histone Acetyltransferase Inhibitor II

Cat.No: T11563

Target: Epigenetic Reader Domain, Histone Acetyltransferase

Cat.No: T9119

Target: Others

Cat.No: T23372

Target: Others

Cat.No: T6421

Target: HDAC

Heptamidine dimethanesulfonate

Cat.No: T11553

Synonym: SBi4211 dimethanesulfonate

Target: Others

L-Selenocystine

Cat.No: T34603

Synonym: L-Selenocystine,L-硒代胱胺基乙酸

Target: Others

Cat.No: T50005

Target: Antifungal

Cat.No: T12006

Synonym: ML246

Target: DNA/RNA Synthesis

Cat.No: T12579

Synonym: PTP1B-IN-9

Target: Proteasome

Cat.No: T5399

Target: PARP

GLPG0634 analog

Cat.No: T3076

Synonym: GLPG0634 analogue

Target: Tyrosine Kinases, JAK

Cat.No: T9024

Synonym: NSC39047

Target: Others, PARP

Cat.No: T9350

Target: Others, DNA/RNA Synthesis

Cat.No: T9098

Synonym: DMG-PEG2000

Target: Others

Cat.No: T0711

Synonym: BAY2353,Niclocide,氯硝柳胺

Target: Antibiotic, STAT, Parasite

Cat.No: T3103

Synonym: DNA Ligase Inhibitor

Target: DNA, DNA/RNA Synthesis

SNS-314 Mesylate

Cat.No: T2617

Synonym: SNS-314

Target: Aurora Kinase

Cat.No: T9079

Synonym: Apt-1

Target: Others

Cat.No: T7020

Synonym: Z-VAD(OH)-FMK,Caspase Inhibitor VI,Z-VAD

Target: Caspase

Prexasertib dihydrochloride

Cat.No: T4327

Synonym: LY2606368 (dihydrochloride),Prexasertib HCl,LY2606368

Target: Apoptosis, Chk, S6 Kinase

Cat.No: T0455

Synonym: 氯氮平,HF 1854,LX 100-129

Target: Dopamine Receptor, Adrenergic Receptor, AChR

Sertaconazole nitrate

Cat.No: T6665

Synonym: FI-7045,Ginedermofix,FI7056,Ertaczo,硝酸舍他康唑

Target: Antibiotic, Antifungal

Cat.No: T15396

Synonym: N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,4-dihydroindeno[1,2-c]pyrazol-3-amine

Target: HIF

Cat.No: T4310

Synonym: 5-[[5-[2-(3-氨基丙氧基)-6-甲氧基苯基]-1H-吡唑-3-基]氨基]-2-吡嗪甲腈,LY2606368

Target: Apoptosis, Chk

Deferasirox (Fe3+ chelate)

Cat.No: T13639

Target: Apoptosis

Phytochelatin 3

Cat.No: T81479

Synonym: PC 3

Cat.No: T30873

Synonym: Chelator1a,Chelator-1a

Target: Antifungal

Phytochelatin 5

Cat.No: T81475

Synonym: PC 5

Phytochelatin 6 TFA

Cat.No: T81472

Synonym: PC 6 TFA

Phytochelatin 4

Cat.No: T81477

Synonym: PC 4

Phytochelatin 5 TFA

Cat.No: T81474

Synonym: PC 5 TFA

Phytochelatin 2 (PC2) (TFA)

Cat.No: T81480

Phytochelatin 3 TFA

Cat.No: T81478

Synonym: PC 3 TFA

Phytochelatin 2 (PC2)

Cat.No: T41109

Phytochelatin 4 TFA

Cat.No: T81476

Synonym: PC 4 TFA

Phytochelatin 6

Cat.No: T81473

Synonym: PC 6

Trachelanthamidine

Cat.No: T124710

Target: Others

Cat.No: T8517

Synonym: PX105684,PXD101,贝利司他,PXD-101

Target: HDAC, Autophagy

Cat.No: T11657

Target: Others

Cat.No: T7181

Synonym: 4-氨基-N-(3-溴-4-氟苯基)-N'-羟基-1,2,5-恶二唑-3-甲脒

Target: Indoleamine 2,3-Dioxygenase (IDO)

Cat.No: T77771

Target: Others

Cat.No: T25214

Synonym: CCR11,CCR 11

Target: Antibiotic

Cat.No: T5342

Target: Wnt/beta-catenin, Porcupine

Cat.No: T25969

Synonym: Poloxin2,Poloxin 2

Target: PLK

Cat.No: T8903

Synonym: Retro 2,2-{[(5-methyl-2-thienyl)methylene]amino}

Target: Others, Virus Protease, Parasite, Autophagy

Cat.No: T8623

Synonym: 4,4,-二(4-氟苯)氯丁烷,1,1'-(4-CHLOROBUTYLIDENE)BIS(4-FLUOROBENZENE),4-oxo-1,4-dihydroquinoline-2-carboxylic acid

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TN7060	Methyl oleanonate	PPAR	DNA Damage/DNA Repair; Metabolism
	Methyl oleanonate 是从柃木中分离得到的一种三萜类天然产物，是齐墩果酸衍生物，是一种PPARγ激动剂，具有抗癌作用。
T11363	Ganoderic acid F	Others	Others
	Ganoderic acid F 是一种灵芝酸。它具有抗肿瘤和抗转移的活性，与抑制血管生成和涉及细胞增殖和细胞死亡，致癌作用，氧化应激，钙信号传导和内质网应激的蛋白质改变等机制相关。
T5S1133	Ganoderic acid D 灵芝酸D,灵芝酸 D	Apoptosis; Sirtuin	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair
	Ganoderic acid D 是高度氧化的四环三萜，是灵芝的主要活性成分，可诱导 HeLa 人宫颈癌细胞凋亡。它上调 SIRT3的蛋白质表达并通过 SIRT3 诱导脱乙酰化的亲环蛋白 D 。它抑制结肠癌细胞的能量重编程，包括结肠癌细胞中的葡萄糖摄取，乳酸、丙酮酸和乙酰辅酶的产生。
T2230	Paeoniflorin 芍药苷,Peoniflorin	HSP; COX	Cytoskeletal Signaling; Immunology/Inflammation; Metabolism; Neuroscience
	Paeoniflorin (Peoniflorin) 是从芍药根中提取的一种蒎烷单萜糖苷，具有抗癌作用、抗氧化应激、抗血小板聚集、血管扩张、降低血液粘度和抗炎活性等多种生物活性。它是一种热休克蛋白诱导剂，通过自噬途径保护 PC12 细胞免受 MPP+和酸性损伤。
T6427	Butein 2’,3,4,4’-tetrahydroxy Chalcone,紫铆因	Apoptosis; EGFR; Others; PDE; Autophagy	Angiogenesis; Apoptosis; Autophagy; JAK/STAT signaling; Metabolism; Others; Tyrosine Kinase/Adaptors
	Butein (2’,3,4,4’-tetrahydroxy Chalcone) 是一种 cAMP 特异性PDE 抑制剂，也是蛋白酪氨酸激酶抑制剂，还是一种SIRT1激活剂。它通过 AKT 和 ERK/p38 MAPK 通路，靶向 FoxO3a 使 HeLa 细胞对 Cisplatin 敏感。
T13475	β-Aminopropionitrile 3-氨基丙腈,3-Aminopropionitrile,BAPN	Others; Endogenous Metabolite	Metabolism; Others
	β-Aminopropionitrile (3-Aminopropionitrile) 是赖氨酰氧化酶的特异性抑制剂。
T4S21320	ISOGINKGETIN 异银杏素,4',4'''-Dimethylamentoflavone,异银杏双黄酮	MMP; Others	Others; Proteases/Proteasome
	ISOGINKGETIN (4',4'''-Dimethylamentoflavone) 是一种MMP9抑制剂，也是一种Pre-mRNA Splicing 抑制剂。
T3673	Mollugin 大叶茜草素,Rubimaillin	HER; JAK	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
	Mollugin (Rubimaillin) 是Rubia cordifolia L.中主要的生物活性成分。它能通过 p38-Smad 信号通路增强 BMP-2 的成骨作用。它通过抑制 TNF-α 诱导的 NF-κB 激活起抗癌疗效。
T14046	Anandamide 花生四烯酸乙醇胺,(5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide	Cannabinoid Receptor; Endogenous Metabolite	GPCR/G Protein; Metabolism
	Anandamide ((5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide) 是一种免疫调节剂，通过大麻素受体 CB1 和 CB2 起作用，还通过中枢神经系统中的其他靶点起作用，如 GPR18/GPR55。
TN1915	Matairesinol 4′-O-β-D-glucopyranoside Matairesinol 4'-O-beta-gentiobioside,罗汉松树脂酚-4'-O-Β-龙胆二糖苷,(3R-反式)-3-[[4-[(6-O-BETA-D-吡喃葡萄糖基-BETA-D-吡喃葡萄糖基)氧基]-3-甲氧基苯基]甲基]二氢-4-[(4-羟基-3-甲氧基苯基)甲基]-2(3H)-呋喃酮	Others	Others
	Matairesinol 4′-O-β-D-glucopyranoside 对 HeLa 细胞具有细胞毒活性(IC50:47.1 μM)。
TC0014	Trachelanthine	Others	Others
	Trachelanthine 是来自 Eupatorium fortunei 的天然产物。
TN5158	Trachelanthamine	Others	Others
	Trachelanthamine is a natural product from Eupatorium fortunei.
TN4375	Kamebanin	Antifection	Microbiology/Virology
	Kamebanin 是一种天然二萜类化合物，具有抗菌活性。它对 HeLa 和 HL-60 细胞显示出有效的细胞毒活性。
T4036	Solasodine Solancarpidine,Purapuridine,澳洲茄铵,Solasodin	Apoptosis; Others; E1/E2/E3 Enzyme; Antifungal	Apoptosis; Microbiology/Virology; Others; Ubiquitination
	Solasodine (Purapuridine) 是存在于茄科植物中的一种类固醇生物碱。它具有神经保护、降压、抗真菌、抗癌、抗动脉粥样硬化、抗雄激素和抗炎活性。
T5738	7-Epi 10-desacetyl paclitaxel 10-Deacetyl-7-epipaclitaxel,7-Epi-10-deacetyltaxol,7-表-10-去乙酰基云南紫杉宁A	Others; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; Others
	7-Epi 10-desacetyl paclitaxel (10-Deacetyl-7-epipaclitaxel) 是紫杉醇衍生物，对 HeLa 细胞具有细胞毒性(IC50:85 μM)。
TN4618	N-trans-Sinapoyltyramine	Others	Others
	N-trans-Sinapoyltyramine 对 HeLa 人癌细胞系表现出强烈的选择性细胞毒性，IC50 值为 9.77 ± 1.25 μm。
TN7041	(-)-Epipodophyllotoxin	Apoptosis	Apoptosis
	(-)-Epipodophyllotoxin 是一种从八角莲中分离的癌细胞抗增殖剂，在 HeLa 细胞和 MCF-7 细胞中的GI50值分别为 0.36 和 0.24 μM。它可在体外抑制有丝分裂纺锤体组装。
TN3049	4-Methoxycinnamyl alcohol	Others	Others
	4-Methoxycinnamyl alcohol 对MCF-7、HeLa 和DU145癌症细胞系显示出毒性，IC50值分别为14.24、7.82和22.10μg/mL。4-methoxycinnamyl alcohol 是从Foeniculum vulgare 中分离出来的。4-Methoxycinnamyl alcohol 没有显示出凋亡作用，却在10μg/mL DNA 碎片研究显示48小时后发生了坏死。
TQ0170	Desacetylcinobufagin Deacetylcinobufagin,去乙酰华蟾蜍精	Others	Others
	Desacetylcinobufagin (Deacetylcinobufagin) 是一种天然化合物，可用于微生物转化。
TN1916	Matairesinol 罗汉松树脂酚	ATPase; p38 MAPK; ROS	Immunology/Inflammation; MAPK; Membrane transporter/Ion channel
	Matairesinol has radical and superoxide scavenging activities,; it also has anti-angiogenic activity by suppressing mROS signaling , can decrease hypoxia-inducible factor-1α± in hypoxic HeLa cells.
TN1393	(-)-Anonaine 番荔枝碱	Apoptosis; Antioxidant; Parasite; Antifungal	Apoptosis; Microbiology/Virology; oxidation-reduction
	(-)-Anonaine 可从木兰科和安妮科的几个物种中提取出来，具有抗疟、抗菌、抗真菌、抗氧化、抗癌、抗抑郁和血管舒张的活性。(-)-Anonaine 通过 Bax 和 caspase 依赖性途径诱导人类宫颈癌（HeLa）细胞的凋亡，诱导 DNA 损伤并抑制人类肺癌 h1299细胞的生长和迁移。
T3386	Kaempferitrin Lespedin,Kaempferol,Lespenephryl,Lespenefril,Kaempferol 3,7-dirhamnoside,山奈苷	cell cycle arrest; Glucokinase; IGF-1R	Cell Cycle/Checkpoint; Metabolism; Tyrosine Kinase/Adaptors
	Kaempferitrin (Lespenephryl) 是天然黄酮苷类化合物，具有缓解疼痛、抗糖尿病、消炎、抗肿瘤和化疗作用，可激活胰岛素信号传导。
TN2755	2-Desoxy-4-epi-pulchellin	Anti-infection	Microbiology/Virology
	2-Desoxy-4-epi-pulchellin 是分离自 Polygonum hydropiper 的二氯甲烷可溶部分的一种化合物。
T3395	Timosaponin AIII Filiferin B,知母皂苷 A-III,AneMarsaponin A3,Timosaponin A3	AChE; mTOR	Neuroscience; PI3K/Akt/mTOR signaling
	Timosaponin AIII (Timosaponin A3) 是一种乙酰胆碱酯酶活性抑制剂，其IC50=35.4 μM。
T6213	Vinorelbine ditartrate Vinorelbine Tartrate,Nor-5'-anhydrovinblastine ditartrate,KW-2307,Navelbine tartrate,长春瑞滨酒石酸盐,酒石酸长春瑞滨	Microtubule Associated; Autophagy	Autophagy; Cytoskeletal Signaling
	Vinorelbine ditartrate (KW-2307)是一种抗有丝分裂剂，能够抑制 Hela 细胞的增殖，IC50值为 1.25 nM。
T3002	Piperine 胡椒碱,1-Piperoylpiperidine,Bioperine	P450; Endogenous Metabolite; P-gp; Autophagy	Autophagy; Membrane transporter/Ion channel; Metabolism; Neuroscience
	Piperine (Bioperine) 是从胡椒中分离的一种生物碱，可以抑制P-糖蛋白和 CYP3A4 的活性，在HeLa 细胞中的IC50值为61.94±0.054 μg/mL。它已用于研究治疗多发性骨髓瘤和吞咽障碍的试验。
T5S0055	Chelidonine Helidonine,Khelidonin,白屈菜碱,Stylophorin	Apoptosis; Others; Influenza Virus	Apoptosis; Microbiology/Virology; Others
	Chelidonine (Stylophorin) 是白屈菜中的一种异喹啉生物碱，有抗肿瘤和抗病毒作用。它可导致细胞周期 G2/M 停滞，诱导 caspase 依赖和非依赖性的细胞凋亡。
T1879	3-Methyladenine 3-MA,3-甲基腺嘌呤,NSC 66389	Mitophagy; PI3K; Endogenous Metabolite; Autophagy	Autophagy; Metabolism; PI3K/Akt/mTOR signaling
	3-Methyladenine (3-MA) 是一种 PI3K 抑制剂，选择性抑制 IB 类 PI3Kγ (IC50=60 μM) 和 III 类 VPS34 (IC50=25 μM)。3-Methyladenine 具有自噬抑制活性。
T0190	Vinorelbine 长春瑞宾,KW-2307 base	Microtubule Associated	Cytoskeletal Signaling
	Vinorelbine (KW-2307 base) 是一种半合成的长春花生物碱。它与微管蛋白结合并阻止有丝分裂纺锤体的形成，导致中期肿瘤细胞生长停滞。
T0122	Bergenin Cuscutin,Bengenin,岩白菜素	Apoptosis; IL Receptor; Virus Protease; TNF; NF-κB; Antibacterial; NOD; Autophagy; Antifungal	Apoptosis; Autophagy; Immunology/Inflammation; Microbiology/Virology; NF-κB
	Bergenin (Bengenin) 是一种在许多药用植物中发现的多酚，有细胞保护和抗氧化作用。它还具有广泛的保肝、抗炎、抗肿瘤、抗病毒、抗真菌以及免疫调节作用。
TN6569	cis-Moschamine
	cis-Moschamine exerts antitumour effects on HeLa, MCF7 and A431 cells.
TN5287	3β,5α-Dihydroxyergosta-7,22-dien-6-one
	3β,5α-Dihydroxy-(22E,24R)-ergosta-7,22-dien-6-one exhibits strong or moderate cytotoxic activities against MCF-7, A549, Hela and KB cell lines with IC50 values 4.98 (MCF-7), 1.95 (A549), 0.68(Hela), and 1.50 uM (KB), respectively.
T83481	1,1′-Disinomenine
	1,1'-Disinomenine，一种从Sinomenium acutum茎部分离得到的生物碱，对A549和Hela细胞表现出较弱的抑制效果。
T35234	Yadanzioside B
	Yadanzioside B 是提取自鸦胆子的苦木素苷类化合物。Yadanzioside B 能够抑制HeLa细胞中的蛋白质合成，但对体外翻译几乎没有影响。
TN3619	Cedrusin	PARP; Caspase	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Proteases/Proteasome
	Cedrusin shows a cytotoxic effect on A375 and HeLa cells.
TN3837	Desmethoxycentaureidin	Others	Others
	Desmethoxycentaureidin shows high inhibitory activity against HeLa cell growth (GI50 9 microM).
T82982	Aplyronine C
	Aplyronine C是一种抗肿瘤活性化合物，对HeLa-S3细胞表现出细胞毒性，其IC50为2.9 nM，适用于癌症研究。
TN7405	Ganolucidic acid E	Others	Others
	Ganolucidic acid E effectively suppresses the proliferation of three human cancer cell lines: Caco-2 (colon cancer), HepG2 (hepatocellular carcinoma), and HeLa (cervical cancer).
TN6399	1-(3',5'-dimethoxy)phenyl-2-[4''-O-beta-D-glucopyranosyl (6->1)-O-alpha-L-rhamnopyranosyl]phenylethane
	1-(3',5'-dimethoxy)phenyl-2-[4''-O-β-D-glucopyranosyl (6→1)-O-α-L-rhamnopyranosyl]phenylethane showed cytotoxic activities to Hela and hep2 cell lines.
T82983	Aplyronine B
	Aplyronine B是一种具有抗肿瘤活性的活性化合物，对HeLa-S3细胞表现出细胞毒性，IC50值为2.9 nM，适用于癌症研究。
TN5212	Uvedalin	Others	Others
	Uvedalin shows cytotoxicity against HeLa, HL-60, and Murine B16-F10 melanoma cell lines.
TN5336	9-Oxo-10,11-dehydroageraphorone 4,7(11)-Cadinadiene-3,8-dione,DTD,7,11-Dehydro-8-oxoageraphorone,泽兰二酮
	9-Oxo-10,11-dehydroageraphorone has acaricidal activity. It induces hepatotoxicity and cholestasis in rats. 9-Oxo-10,11-dehydroageraphorone also effectively inhibits the proliferation of HeLa cells by arresting the cell cycle transition from S to G2/M pha
T79991	Condurango glycoside A	Others	Others
	Condurango glycoside A 作为p53激活剂，能够促进ROS的生成并且上调p53的表达。此外，Condurango glycoside A 还能够诱导HeLa细胞发生与DNA损伤相关的凋亡及过早老化。
TN2964	3'-Methylflavokawin	Others	Others
	3'-Methylflavokawin shows cytotoxicity against HeLa cells, the IC 50 value comparable to xanthohumol (8.2-19.2 microM).
T37444	Aranorosin	Others	Others
	Aranorosin is a fungal metabolite originally isolated from P. roseus. It has antimicrobial activity against B. subtilis, A. niger, and C. albicans when used at a concentration of 1 mg/ml. Aranorosin also reduces viability in apoptosis-resistant HeLa/Bcl-2 cells.
TN5574	Heudelotinone
	Heudelotinone shows cytotoxicity against three cancer cell lines A549, Hela, and SMMC-7721( IC50 values of 16.04, 10.67 and 21.68 uM , respectively).
TN1776	Isocucurbitacin B	Others	Others
	Isocucurbitacin B 对 HeLa 和 HT-29 人类癌细胞具有显着的抑制活性，IC50 值范围为 0.93 至 9.73uM。
TN2142	Resibufagin	Others	Others
	Resibufagin shows strong cytotoxic activity against HeLa cell line.
T81602	Ophiopogonin R
	Ophiopogonin R (compound 3)，一种甾体皂苷，源自麦冬的分离纯化。该化合物对包括HepG2、HLE、BEL7402、BEL7403和Hela在内的五种人类肿瘤细胞系均未显示细胞毒性。
TN5093	Taiwanhomoflavone A	COX	Immunology/Inflammation; Neuroscience
	Taiwanhomoflavone A is cytotoxic with ED50 values of 3.4, 1.0, 2.0 and 2.5 microg/ml, respectively, against KB epidermoid carcinoma of nasopharynx, COLO-205 colon carcinoma, Hepa-3B hepatoma, and Hela cervix tumor cells.
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天然产物

Methyl oleanonate

Cat.No: TN7060

Target: PPAR

Ganoderic acid F

Cat.No: T11363

Target: Others

Ganoderic acid D

Cat.No: T5S1133

Synonym: 灵芝酸D,灵芝酸 D

Target: Apoptosis, Sirtuin

Cat.No: T2230

Synonym: 芍药苷,Peoniflorin

Target: HSP, COX

Cat.No: T6427

Synonym: 2’,3,4,4’-tetrahydroxy Chalcone,紫铆因

Target: Apoptosis, EGFR, Others, PDE, Autophagy

β-Aminopropionitrile

Cat.No: T13475

Synonym: 3-氨基丙腈,3-Aminopropionitrile,BAPN

Target: Others, Endogenous Metabolite

Cat.No: T4S21320

Synonym: 异银杏素,4',4'''-Dimethylamentoflavone,异银杏双黄酮

Target: MMP, Others

Cat.No: T3673

Synonym: 大叶茜草素,Rubimaillin

Target: HER, JAK

Cat.No: T14046

Synonym: 花生四烯酸乙醇胺,(5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide

Target: Cannabinoid Receptor, Endogenous Metabolite

Matairesinol 4′-O-β-D-glucopyranoside

Cat.No: TN1915

Synonym: Matairesinol 4'-O-beta-gentiobioside,罗汉松树脂酚-4'-O-Β-龙胆二糖苷,(3R-反式)-3-[[4-[(6-O-BETA-D-吡喃葡萄糖基-BETA-D-吡喃葡萄糖基)氧基]-3-甲氧基苯基]甲基]二氢-4-[(4-羟基-3-甲氧基苯基)甲基]-2(3H)-呋喃酮

Target: Others

Cat.No: TC0014

Target: Others

Trachelanthamine

Cat.No: TN5158

Target: Others

Cat.No: TN4375

Target: Antifection

Cat.No: T4036

Synonym: Solancarpidine,Purapuridine,澳洲茄铵,Solasodin

Target: Apoptosis, Others, E1/E2/E3 Enzyme, Antifungal

7-Epi 10-desacetyl paclitaxel

Cat.No: T5738

Synonym: 10-Deacetyl-7-epipaclitaxel,7-Epi-10-deacetyltaxol,7-表-10-去乙酰基云南紫杉宁A

Target: Others, ADC Cytotoxin

N-trans-Sinapoyltyramine

Cat.No: TN4618

Target: Others

(-)-Epipodophyllotoxin

Cat.No: TN7041

Target: Apoptosis

4-Methoxycinnamyl alcohol

Cat.No: TN3049

Target: Others

Desacetylcinobufagin

Cat.No: TQ0170

Synonym: Deacetylcinobufagin,去乙酰华蟾蜍精

Target: Others

Cat.No: TN1916

Synonym: 罗汉松树脂酚

Target: ATPase, p38 MAPK, ROS

Cat.No: TN1393

Synonym: 番荔枝碱

Target: Apoptosis, Antioxidant, Parasite, Antifungal

Cat.No: T3386

Synonym: Lespedin,Kaempferol,Lespenephryl,Lespenefril,Kaempferol 3,7-dirhamnoside,山奈苷

Target: cell cycle arrest, Glucokinase, IGF-1R

2-Desoxy-4-epi-pulchellin

Cat.No: TN2755

Target: Anti-infection

Timosaponin AIII

Cat.No: T3395

Synonym: Filiferin B,知母皂苷 A-III,AneMarsaponin A3,Timosaponin A3

Target: AChE, mTOR

Vinorelbine ditartrate

Cat.No: T6213

Synonym: Vinorelbine Tartrate,Nor-5'-anhydrovinblastine ditartrate,KW-2307,Navelbine tartrate,长春瑞滨酒石酸盐,酒石酸长春瑞滨

Target: Microtubule Associated, Autophagy

Cat.No: T3002

Synonym: 胡椒碱,1-Piperoylpiperidine,Bioperine

Target: P450, Endogenous Metabolite, P-gp, Autophagy

Cat.No: T5S0055

Synonym: Helidonine,Khelidonin,白屈菜碱,Stylophorin

Target: Apoptosis, Others, Influenza Virus

3-Methyladenine

Cat.No: T1879

Synonym: 3-MA,3-甲基腺嘌呤,NSC 66389

Target: Mitophagy, PI3K, Endogenous Metabolite, Autophagy

Cat.No: T0190

Synonym: 长春瑞宾,KW-2307 base

Target: Microtubule Associated

Cat.No: T0122

Synonym: Cuscutin,Bengenin,岩白菜素

Target: Apoptosis, IL Receptor, Virus Protease, TNF, NF-κB, Antibacterial, NOD, Autophagy, Antifungal

Cat.No: TN6569

3β,5α-Dihydroxyergosta-7,22-dien-6-one

Cat.No: TN5287

1,1′-Disinomenine

Cat.No: T83481

Cat.No: T35234

Cat.No: TN3619

Target: PARP, Caspase

Desmethoxycentaureidin

Cat.No: TN3837

Target: Others

Cat.No: T82982

Ganolucidic acid E

Cat.No: TN7405

Target: Others

1-(3',5'-dimethoxy)phenyl-2-[4''-O-beta-D-glucopyranosyl (6->1)-O-alpha-L-rhamnopyranosyl]phenylethane

Cat.No: TN6399

Cat.No: T82983

Cat.No: TN5212

Target: Others

9-Oxo-10,11-dehydroageraphorone

Cat.No: TN5336

Synonym: 4,7(11)-Cadinadiene-3,8-dione,DTD,7,11-Dehydro-8-oxoageraphorone,泽兰二酮

Condurango glycoside A

Cat.No: T79991

Target: Others

3'-Methylflavokawin

Cat.No: TN2964

Target: Others

Cat.No: T37444

Target: Others

Cat.No: TN5574

Isocucurbitacin B

Cat.No: TN1776

Target: Others

Cat.No: TN2142

Target: Others

Cat.No: T81602

Taiwanhomoflavone A

Cat.No: TN5093

Target: COX

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Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-01332	Ferrochelatase Protein, Human, Recombinant (His & Myc) Ferrochelatase, mitochondrial,Heme synthase,Protohe...	Human	E. coli
	Catalyzes the ferrous insertion into protoporphyrin IX. Ferrochelatase Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 49.6 kDa and the accession number is P22830.
TMPH-00265	Ferrochelatase, mitochondrial Protein, Bovine, Recombinant (His & Myc & SUMO) Ferrochelatase, mitochondrial,Protoheme ferro-lyase...	Bovine	E. coli
	Catalyzes the ferrous insertion into protoporphyrin IX. Ferrochelatase, mitochondrial Protein, Bovine, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Mycd tag. The predicted molecular weight is 58.1 kDa and the accession number is P22600.
TMPY-00570	Alkaline Phosphatase/PLAP Protein, Human, Recombinant (His) ALPI,PALP,PLAP,PLAP-1,alkaline phosphatase, placental,IAP,AL...	Human	P. pastoris (Yeast)
	Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is overexpressed on many cancer cells, dephosphorylate the d-tyrosine phosphates on the surface of the magnetic nanoparticle and enable the magnetic nanoparticles to adhere selectively to the cancer cells, such as HeLa cells. Placental alkaline phosphatase (PLAP), encoded by the ALPP gene, is produced by the fetal side of the placenta.
TMPY-02521	HIST3H2A Protein, Human, Recombinant histone cluster 3, H2a,MGC3165	Human	E. coli
	Histones are a complex family of highly conserved basic proteins responsible for packaging chromosomal DNA into nucleosomes. There are subtype diversities: H1, H2A, H2B, and H3 or H4. It has become more and more evident that histone modifications are key players in the regulation of chromatin states and dynamics as well as in gene expression. Therefore, histone modifications and the enzymatic machinery that set them are crucial regulators that can control cellular proliferation, differentiation,...
TMPH-00604	CDTA Protein, E. coli, Recombinant (His) Cytolethal distending toxin subunit A,CDTA,CDT A	E. coli	E. coli
	CDTs are cytotoxins which induce host cell distension, growth arrest in G2/M phase, nucleus swelling, and chromatin fragmentation in HeLa cells. CdtA, along with CdtC, probably forms a heterodimeric subunit required for the delivery of CdtB.
TMPH-03026	CARDS Protein, Mycoplasma pneumoniae, Recombinant (His & Myc) ADP-ribosylating toxin CARDS,CARDX TX,ADP-ribosyltransferase...	Mycoplasma pneumoniae	E. coli
	Acts as an ADP-ribosylating toxin, which may transfer the ADP-ribosyl group from NAD(+) to specific amino acids in target proteins. Elicits cytopathic effects in mammalian cells, such as disorganization and disruption of respiratory epithelial integrity in tracheal epithelium and vacuolization in the cytoplasm of CHO and HeLa cells.
TMPJ-00546	EFNA1 Protein, Human, Recombinant (hFc) TNFAIP4,LERK1,Tumor Necrosis Factor α-Induced Protein 4,Imme...	Human	HEK293 Cells
	Ephrin-A1 is a member of the A-type ephrin family of cell surface proteins that function as ligands for the A-type Eph receptor tyrosine kinase family. Ephrin-A1 can be induced by TNF and IL1B. Its expression levels can be down-regulated in primary glioma tissues compared to the normal tissues. The soluble monomeric form is expressed in the glioblastoma multiforme (GBM) and breast cancer cells. Soluble Ephrin-A1 is necessary for the transformation of HeLa and SK-BR3 cells and participates in the...
TMPY-02132	LYPLA2 Protein, Human, Recombinant (His) APT-2,lysophospholipase II,DJ886K2.4,APT2	Human	E. coli
	Lysophospholipase II (LYPLA2, LPL-II, or LysoPLA II), also known as Acyl-protein thioesterase 2 (APT-2), belongs to the AB hydrolase 2 family. This enzyme has lysophospholipase activity and may hydrolyze fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Acyl-protein thioesterase 1 (APT-1) and Acyl-protein thioesterase 2 (APT-2) are cytosolic lysophospholipids hydrolyzing enzymes. The serum activity of APT-1 may play an important role in the dete...
TMPY-03397	TPPP3 Protein, Human, Recombinant (His) CGI-38,TPPP3,p25gamma,tubulin polymerization-promoting prote...	Human	E. coli
	TPPP3, a member of the Tubulin polymerization-promoting protein family, is an intrinsically unstructured protein that induces tubulin polymerization. TPPP3 is a marker in the developing musculoskeletal system. In tendons, Tppp3 is expressed in cells at the circumference of the developing tendons, likely the progenitors of connective tissues that surround tendons: the tendon sheath, epitenon, and paratenon. Tppp3 is also expressed in forming synovial joints. The onset of Tppp3 expression in joint...

重组蛋白

Ferrochelatase Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01332

Species: Human

Expression System: E. coli

Ferrochelatase, mitochondrial Protein, Bovine, Recombinant (His & Myc & SUMO)

Cat.No: TMPH-00265

Species: Bovine

Expression System: E. coli

Alkaline Phosphatase/PLAP Protein, Human, Recombinant (His)

Cat.No: TMPY-00570

Species: Human

Expression System: P. pastoris (Yeast)

HIST3H2A Protein, Human, Recombinant

Cat.No: TMPY-02521

Species: Human

Expression System: E. coli

CDTA Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00604

Species: E. coli

Expression System: E. coli

CARDS Protein, Mycoplasma pneumoniae, Recombinant (His & Myc)

Cat.No: TMPH-03026

Species: Mycoplasma pneumoniae

Expression System: E. coli

EFNA1 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00546

Species: Human

Expression System: HEK293 Cells

LYPLA2 Protein, Human, Recombinant (His)

Cat.No: TMPY-02132

Species: Human

Expression System: E. coli

TPPP3 Protein, Human, Recombinant (His)

Cat.No: TMPY-03397

Species: Human

Expression System: E. coli

Cat. No.	Product Name	Target	Signaling Pathways
T69600	Spermidine-d6
	Spermidine-d6 is intended for use as an internal standard for the quantification of spermidine by GC- or LC-MS. Spermidine is an endogenous polyamine. It is formed from putrescine by spermidine synthase. Spermidine (25 µM) inhibits the activity of the human inward-rectifying potassium channel Kir2.3 in a patch-clamp assay. It induces autophagy in HeLa cells when used at a concentration of 100 µM and increases the lifespan of D. melanogaster, yeast, and C. elegans. Spermidine (30 mM in the drinki...

同位素标记化合物

Cat.No: T69600

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