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Search Results for " hbf "

Targets Recommended: Antiviral

抑制剂 & 化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T27527	HBF-0259 HBF 0259	Antiviral	Immunology/Inflammation
	HBF-0259 是有效的乙型肝炎病毒表面抗原分泌选择性抑制剂，在 HepG2.2.15 细胞中的 EC50为 1.5 μM。
T60898	HbF inducer-1	Others	Others
	HbF inducer-1 是一种胎儿血红蛋白诱导剂，具有口服生物活性。
T21652	RN-1 dihydrochloride	Histone Demethylase; MAO	Chromatin/Epigenetic; Metabolism; Neuroscience
	RN-1 dihydrochloride 是血脑屏障通透性的、不可逆的赖氨酸特异性脱甲基酶 1 (LSD1) 选择性抑制剂，IC50为 70 nM，对 LSD1 的选择性高于 MAO-A 和 MAO-B，IC50分别为 0.51 μM 和 2.785 μM。
T19583	TN1	Others	Others
	TN1 是一种有效的胎儿型血红蛋白 (HbF) 诱导剂。
T23315	SB 216641 hydrochloride SB-216641A,SB-216641 hydrochloride,SB216641A,SB 216641A	5-HT Receptor	GPCR/G Protein; Neuroscience
	SB 216641 hydrochloride (SB-216641A) 是一种选择性的 5-HT1B/D 受体拮抗剂，具有抗焦虑作用，拮抗舒马普坦介导的血管收缩反应。
T40154	FTX-6058	Others	Others
	FTX-6058 is a potent orally active inhibitor targeting Embryonic Ectoderm Development (EED). It effectively induces HbF protein expression in both cell and murine models. This compound holds significant potential for researching select hemoglobinopathies such as sickle cell disease and β-thalassemia.
T73517	RK-701	Others	Others
	RK-701 是一种G9a 高选择性且非遗传毒性的抑制剂，IC50值为 23-27 nM。RK-701 选择性的上调 HbF、γ- Globin、BGLT3 的表达，下调 H3K9me2 的表达。RK-701 也对 BCL11A 和 ZBTB7A 有抑制作用。
T40155	FTX-6058 hydrochloride	Others	Others
	FTX-6058 hydrochloride is a potent and orally active inhibitor of Embryonic Ectoderm Development (EED), with the ability to induce HbF protein expression in both cell and murine models. This compound is particularly valuable in the research of select hemoglobinopathies, such as sickle cell disease and β-thalassemia.

化合物

HBF-0259

Cat.No: T27527

Synonym: HBF 0259

Target: Antiviral

Target: Histone Demethylase, MAO

SB 216641 hydrochloride

Cat.No: T23315

Synonym: SB-216641A,SB-216641 hydrochloride,SB216641A,SB 216641A

Target: 5-HT Receptor

FTX-6058 hydrochloride

Cat.No: T40155

Synonym:

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TN5222	Vasicinol 6-Hydroxypeganine	Others	Others
	Vasicinol (6-Hydroxypeganine) 是一种可从Adhatoda vasica （L.）， Nees 中分离出来的吡咯喹唑啉生物碱，是蔗糖酶抑制剂，抑制大鼠肠道α-葡萄糖苷酶的蔗糖水解活性，Ki值为183μM。Vasicinol 是一种 HbF 诱导剂，可用研究代谢紊乱和糖尿病。