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Cat. No.	Product Name	Target	Signaling Pathways
T41062	HXR9
	HXR9 is a cell-permeable peptide that acts as a competitive antagonist of the HOX/PBX interaction. It effectively inhibits the binding between HOX proteins and the transcription factor PBX, specifically in paralogue groups 1 to 8. HXR9 selectively impairs cell proliferation and induces apoptosis in cells with a high expression of the HOXA/PBX3 genes, for instance, MLL-rearranged leukemic cells.
T76213	HXR9 hydrochloride
	HXR9 hydrochloride 是一种针对 HOX/PBX 相互作用的细胞渗透性肽类竞争性拮抗剂。它通过阻碍 HOX 蛋白与 PBX，一个与旁系同源基因组 1 至 8 结合的第二转录因子，之间的相互作用来发挥作用。特别地，HXR9 hydrochloride 能够选择性抑制细胞增殖，并在表达 HOXA/PBX3 基因高水平的细胞中，如 MLL 重排的白血病细胞，促进细胞凋亡。