Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T70044 |
Sarizotan HCl
EMD 128130 HCl |
5-HT Receptor; HER | Angiogenesis; GPCR/G Protein; JAK/STAT signaling; Neuroscience; Tyrosine Kinase/Adaptors |
Sarizotan HCl (EMD 128130 HCl) 是一种 hERG 通道抑制剂和 5-羟色胺5-HT1A受体激动剂,具有潜在的抗抑郁作用,可用于研究帕金森运动障碍 | |||
T70045 |
HUN47990
|
Others | Others |
HUN47990 is a bisphosphonate (BP) prodrug with antitumor activity. HUN47990 potently inhibits the in vitro growth of a variety of tumor cell lines, especially hematopoietic cell lines, at nanomolar concentrations. HUN47990 inhibited the prenylation of the RAP1A small GTPase signaling protein at concentrations as low as 1-10 nM. HUN47990 slowed the growth of human bladder cancer cells in an immunodeficient mouse model. HUN47990 is significantly more active than zoledronic acid, the most active FD... |