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Targets Recommended: 5-HT Receptor HER

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Cat. No. Product Name Target Signaling Pathways
T70044 Sarizotan HCl

EMD 128130 HCl

5-HT Receptor; HER Angiogenesis; GPCR/G Protein; JAK/STAT signaling; Neuroscience; Tyrosine Kinase/Adaptors
Sarizotan HCl (EMD 128130 HCl) 是一种 hERG 通道抑制剂和 5-羟色胺5-HT1A受体激动剂,具有潜在的抗抑郁作用,可用于研究帕金森运动障碍
T70045 HUN47990

Others Others
HUN47990 is a bisphosphonate (BP) prodrug with antitumor activity. HUN47990 potently inhibits the in vitro growth of a variety of tumor cell lines, especially hematopoietic cell lines, at nanomolar concentrations. HUN47990 inhibited the prenylation of the RAP1A small GTPase signaling protein at concentrations as low as 1-10 nM. HUN47990 slowed the growth of human bladder cancer cells in an immunodeficient mouse model. HUN47990 is significantly more active than zoledronic acid, the most active FD...

化合物

Sarizotan HCl
Cat.No: T70044
Synonym: EMD 128130 HCl
Target: 5-HT Receptor, HER
HUN47990
Cat.No: T70045
Synonym:
Target: Others
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