20
2
34
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TP1595 |
Human Papillomavirus (HPV) E7 protein (49-57)
Human Papillomavirus (HPV) E7 protein 49-57 |
||
Human Papillomavirus (HPV) E7 protein (49-57) is the H-2d-restricted human papillomavirus (HPV) E749-57 epitope. | |||
T8350 |
TPCK
|
Proteasome | Proteases/Proteasome; Ubiquitination |
TPCK 是丝氨酸蛋白酶抑制剂,通过与 HPV-18 E7 蛋白的视网膜母细胞瘤蛋白 (RB) 结合核心发生反应,并能够消除其 RB 结合能力。将它添加到培养基内,可修饰活角质形成细胞中的 E7 蛋白。 | |||
T12711 |
Retro-2 cycl
RN 1-001 |
Virus Protease | Microbiology/Virology |
Retro-2 cycl 是一种抗病毒剂,是一种逆行运输抑制剂,抑制 JCPyV(IC50s:54 μM)和 HPV16 假病毒(IC50s:160 μM)。 | |||
TP1554L |
HPV16 E7 (86-93) acetate
HPV16 E7 (86-93) acetate(160212-93-1 Free base) |
Others | Others |
HPV16 E7 (86-93) acetate 是人源白细胞抗原 A2.1 限制性 HPV16 E7 的衍生肽,在宫颈癌中具有免疫原性。 | |||
T1583 |
Vorinostat
MK0683,伏立诺他,suberoylanilide hydroxamic acid,SAHA |
Apoptosis; Mitophagy; Virus Protease; HDAC; Autophagy | Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; Microbiology/Virology |
Vorinostat (SAHA) 是一种泛的组蛋白脱乙酰酶 (HDAC) 抑制剂 (IC50=10 nM),对 HDAC1/2/3/6/7/11 均有抑制活性。 Vorinostat 具有抗肿瘤活性,可以诱导细胞分化,阻滞细胞周期,诱导细胞凋亡。 | |||
TP1554 |
HPV16 E7 (86-93)
|
||
This is amino acids 86 to 93 fragment of the human papilloma virus (HPV) type 16 oncoprotein E7. This HPV16-encoded peptide has very high affinity of binding to the HLA-A*0201 molecule.This immunogenic fragment may be used in vaccines for the prevention a | |||
TP1515 |
HPV16-E711-20 epitope
|
||
HPV16-E711-20 epitope is a well-known HLA-A*0201-restricted human cytotoxic T lymphocyte (CTL) epitope of the HPV16 E7 protein that shows high-affinity binding to HLA-A2 in vitro. | |||
T60544 |
HPV18-IN-1
|
Others | Others |
HPV18-IN-1 (Compound H1) 是有效的HPV18抑制剂,可防止宫颈癌细胞的过早和异常细胞增殖。它可抑制 E7-Rb-E2F 细胞通路和 DNA 甲基化, 具有癌症研究的潜力。 | |||
T76015 |
HPV16 E7 (86-93) (TFA)
|
||
HPV16 E7 (86-93) TFA,一种HLA-A2.1限制的HPV16 E7衍生肽,在宫颈癌中显示出免疫原性。 | |||
TP1525 |
HPV16 E7 (86-93) (TFA)(160212-93-1,free)
HPV16 E7 (86-93) (TFA) |
||
HPV16 E7 (86-93) TFA is a human leukocyte antigen (HLA)-A2.1 restricted HPV16 E7-derived peptide. | |||
T12042 |
Minnelide
|
Apoptosis; Virus Protease | Apoptosis; Microbiology/Virology |
Minnelide 是水溶性雷公藤内酯前药,具有抗癌症抗肿瘤活性,可诱导细胞凋亡,可预防足细胞损伤。Minnelide 通过阻断 HPV 诱导的 p53 和 pRb 变化来抑制宫颈癌的生长。 | |||
T25466 |
GS-9191
GS 9191 |
DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
GS-9191是一种DNA 聚合酶α和ß 的强效抑制剂 ,是一种新型核苷类似物9-(2-膦酰甲氧基乙基)鸟嘌呤(PMEG)的原药 ,可渗透皮肤并在上皮层代谢为活性核苷三磷酸类似物。GS-9191具有抗增殖活性,以剂量相关的方式减少乳头瘤的大小。GS-9191可能对治疗HPV 引起的病变有作用。 | |||
T77423 |
Lirilumab
ONO-4483,IPH2102 |
Virus Protease | Microbiology/Virology |
Lirilumab (IPH2102) 是一种针对杀伤性免疫球蛋白样受体抗体 KIR2D 的抗体,具有抗肿瘤活性,通过 Vav1 依赖性 NF-κB 去抑制增强自然杀伤细胞的抗 HPV+ 宫颈癌活性,可用于研究白血病、头颈部鳞状细胞癌 (SCCHN)。 | |||
T17228 |
Sabizabulin
ABI-231,VERU-111 |
Microtubule Associated | Cytoskeletal Signaling |
Sabizabulin (ABI-231) 是一种有效且具有口服生物利用度的 α 和 β 微管蛋白抑制剂,可对抗黑色素瘤和前列腺癌细胞系。 Sabizabulin 通过靶向 HPV E6 和 E7 抑制宫颈癌细胞的肿瘤生长和转移表型。 Sabizabulin 显示出抗增殖活性,可用于前列腺癌研究。 | |||
T71941 |
Lig3
|
Others | Others |
Lig3 is an inhibitor against high-risk strains of human papillomavirus (HPV) E6 oncoprotein. | |||
T28534 |
RH02007
CCG 40788,RH-02007,CCG40788,CCG-40788,RH 02007 |
Others | Others |
RH02007 is an inhibitor of the human papillomavirus (HPV) E6 oncoprotein. | |||
T76960 |
Verpasep caltespen
|
Others | Others |
Verpasep caltespen (HspE7) 是一种重组融合蛋白,来源于Mycobacterium bovis Calmette-Guérin 热休克蛋白 65 (Hsp65),其 C 末端与HPV16 的 E7 蛋白共价连接。Verpasep caltespen 可用于人乳头瘤病毒 (HPV)引起的癌前病变和癌性病变研究。 | |||
T72241 |
Teslexivir hydrochloride
BTA074 hydrochloride ; AP 611074 hydrochloride,BTA074 hydrochloride,AP 611074 hydrochloride |
Others | Others |
Teslexivir (BTA074) hydrochloride 是一种有效的抗病毒剂。Teslexivir hydrochloride 是两种关键病毒蛋白 (E1和 E2) 相互作用的强效选择性抑制剂,这两种蛋白的相互作用是人乳头瘤病毒 (HPV) 6 和 11 的 DNA 复制和病毒产生的重要步骤。Teslexivir hydrochloride 可用于尖锐湿疣的研究。 | |||
T76336 |
Astodrimer
|
||
Astodrimer (SPL7013 free base) 是一种体积较大(3-4 nm, ~ 16.5 kDa)、带负电荷、高度分支化的树状高分子,有效抑制并杀灭多种病毒,包括 SARS-CoV-2、HIV-1、HSV-1、HSV-2、HPV 等,具有广谱的抗病毒和杀病毒活性,同时展现出抗菌特性。 | |||
T80375 |
Human α-defensin 5
|
Parasite | Microbiology/Virology |
Human α-defensin 5 是抗病毒肽,能够阻断多种无包膜病毒感染,如AdV、HPV以及多瘤病毒(IC50: HPV16为0.6-1.25 μM)。它通过与病毒衣壳结合来阻止病毒从内体逃逸,并能增强HIV与细胞表面的结合作用。此外,Human α-defensin 5 还具备对抗寄生虫的活性。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN4417 |
Larixyl acetate
|
Others | Others |
Larixyl acetate 是一种生物活性化学物质。 | |||
T79941 |
Antimycin A2c
|
Apoptosis | Apoptosis |
Anticanceragent 141(compound AE)是一种针对HPV感染宫颈癌具有抑制作用的抗霉素生物碱。该化合物能够抑制宫颈癌HeLa细胞的增殖并导致细胞周期在S期停滞。Anticanceragent 141破坏线粒体功能,诱导caspase依赖性细胞凋亡,并激活ROS介导的泛素依赖性蛋白酶体系统,进而引起E6/E7癌蛋白的降解。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-05410 |
Human Papilloma Virus type 56 (HPV 56) L1 Protein-VLP
|
HPV | Baculovirus Insect Cells |
Human Papilloma Virus type 56 (HPV 56) L1 Protein-VLP is expressed in Baculovirus insect cells. The predicted molecular weight is 56 kDa. | |||
TMPY-05406 |
Human Papilloma Virus type 39 (HPV 39) L1 Protein-VLP
|
HPV | Baculovirus Insect Cells |
Human Papilloma Virus type 39 (HPV 39) L1 Protein-VLP is expressed in Baculovirus insect cells. The predicted molecular weight is 57 kDa. | |||
TMPY-05404 |
Human Papilloma Virus type 33 (HPV 33) L1 Protein-VLP
|
HPV | Baculovirus Insect Cells |
Human Papilloma Virus type 33 (HPV 33) L1 Protein-VLP is expressed in Baculovirus insect cells. The predicted molecular weight is 56 kDa. | |||
TMPY-05412 |
Human Papilloma Virus type 59 (HPV 59) L1 Protein-VLP
|
HPV | Baculovirus Insect Cells |
Human Papilloma Virus type 59 (HPV 59) L1 Protein-VLP is expressed in Baculovirus insect cells. The predicted molecular weight is 57 kDa. | |||
TMPH-01828 |
Human Papilloma Virus type 11 (HPV 11) Regulatory Protein E2 (His & Myc)
E2,Regulatory protein E2 |
HPV 11 | E. coli |
Human Papilloma Virus type 11 (HPV 11) Regulatory Protein E2 (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 49.2 kDa and the accession number is P04015. | |||
TMPY-05399 |
Human Papilloma Virus type 6 (HPV 6) L1 Protein-VLP
|
HPV | Baculovirus Insect Cells |
Human Papilloma Virus type 6 (HPV 6) L1 Protein-VLP is expressed in Baculovirus insect cells. The predicted molecular weight is 55 kDa. | |||
TMPY-05411 |
Human Papilloma Virus type 58 (HPV 58) L1 Protein-VLP
|
HPV | Baculovirus Insect Cells |
Human Papilloma Virus type 58 (HPV 58) L1 Protein-VLP is expressed in Baculovirus insect cells. The predicted molecular weight is 56 kDa. | |||
TMPH-01833 |
Human Papilloma Virus type 16 (HPV 16) Protein E6 (His)
Protein E6,E6 |
HPV 16 | P. pastoris (Yeast) |
Human Papilloma Virus type 16 (HPV 16) Protein E6 (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 21.2 kDa and the accession number is P03126. | |||
TMPH-01834 |
Human Papilloma Virus type 16 (HPV 16) Protein E7 (His)
Protein E7,E7 |
HPV 16 | E. coli |
Human Papilloma Virus type 16 (HPV 16) Protein E7 (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 15.0 kDa and the accession number is P03129. | |||
TMPY-05407 |
Human Papilloma Virus type 45 (HPV 45) L1 Protein-VLP
|
HPV | Baculovirus Insect Cells |
Human Papilloma Virus type 45 (HPV 45) L1 Protein-VLP is expressed in Baculovirus insect cells. The predicted molecular weight is 56 kDa. | |||
TMPY-05402 |
Human Papilloma Virus type 18 (HPV 18) L1 Protein-VLP
|
HPV | Baculovirus Insect Cells |
Human Papilloma Virus type 18 (HPV 18) L1 Protein-VLP is expressed in Baculovirus insect cells. The predicted molecular weight is 56 kDa. | |||
TMPY-05409 |
Human Papilloma Virus type 52 (HPV 52) L1 Protein-VLP
|
HPV | Baculovirus Insect Cells |
Human Papilloma Virus type 52 (HPV 52) L1 Protein-VLP is expressed in Baculovirus insect cells. The predicted molecular weight is 56 kDa. | |||
TMPH-01837 |
Human Papilloma Virus type 18 (HPV 18) Protein E7 (His)
Protein E7,E7 |
HPV 18 | P. pastoris (Yeast) |
Human Papilloma Virus type 18 (HPV 18) Protein E7 (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 14.0 kDa and the accession number is P06788. | |||
TMPY-05403 |
Human Papilloma Virus type 31 (HPV 31) L1 Protein-VLP
|
HPV | Baculovirus Insect Cells |
Human Papilloma Virus type 31 (HPV 31) L1 Protein-VLP is expressed in Baculovirus insect cells. The predicted molecular weight is 56 kDa. | |||
TMPY-05401 |
Human Papilloma Virus type 16 (HPV 16) L1 Protein-VLP
|
HPV | Baculovirus Insect Cells |
Human Papilloma Virus type 16 (HPV 16) L1 Protein-VLP is expressed in Baculovirus insect cells. The predicted molecular weight is 56 kDa. | |||
TMPY-05405 |
Human Papilloma Virus type 35 (HPV 35) L1 Protein-VLP
|
HPV | Baculovirus Insect Cells |
Human Papilloma Virus type 35 (HPV 35) L1 Protein-VLP is expressed in Baculovirus insect cells. The predicted molecular weight is 56 kDa. | |||
TMPY-05400 |
Human Papilloma Virus type 11 (HPV 11) L1 Protein-VLP
|
HPV | Baculovirus Insect Cells |
Human Papilloma Virus type 11 (HPV 11) L1 Protein-VLP is expressed in Baculovirus insect cells. The predicted molecular weight is 55 kDa. | |||
TMPH-01826 |
Human Papilloma Virus type 11 (HPV 11) Protein E4 (His)
E4,Protein E4 |
HPV 11 | E. coli |
Human Papilloma Virus type 11 (HPV 11) Protein E4 (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 16.0 kDa and the accession number is P04016. | |||
TMPH-01829 |
Human Papilloma Virus type 11 (HPV 11) Regulatory Protein E1 (His)
ATP-dependent helicase E1,E1,Replication protein E1 |
HPV 11 | E. coli |
Human Papilloma Virus type 11 (HPV 11) Regulatory Protein E1 (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 23.1 kDa and the accession number is P04014. | |||
TMPH-01827 |
Human Papilloma Virus type 11 (HPV 11) Protein E7 (His & Myc)
E7,Protein E7 |
HPV 11 | E. coli |
Human Papilloma Virus type 11 (HPV 11) Protein E7 (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.3 kDa and the accession number is P04020. | |||
TMPH-01835 |
Human Papilloma Virus type 18 (HPV 18) Minor capsid Protein L2 (His)
Minor capsid protein L2,L2 |
HPV 18 | P. pastoris (Yeast) |
Human Papilloma Virus type 18 (HPV 18) Minor capsid Protein L2 (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 51.6 kDa and the accession number is P06793. | |||
TMPH-01838 |
Human Papilloma Virus type 52 (HPV 52) Protein E7 (His & SUMO)
E7,Protein E7 |
HPV 52 | E. coli |
Human Papilloma Virus type 52 (HPV 52) Protein E7 (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 27.0 kDa and the accession number is P36831. | |||
TMPH-01831 |
Human Papilloma Virus type 16 (HPV 16) Protein E4 (His & Myc)
Protein E4,E4,E1^E4 |
HPV 16 | E. coli |
Human Papilloma Virus type 16 (HPV 16) Protein E4 (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 17.5 kDa and the accession number is P06922. | |||
TMPH-01839 |
Human Papilloma Virus type 6a (HPV 6a) Protein E4 (His & Myc)
Protein E4,E4 |
HPV 6a | E. coli |
Human Papilloma Virus type 6a (HPV 6a) Protein E4 (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 17.7 kDa and the accession number is Q84295. | |||
TMPH-01836 |
Human Papilloma Virus type 18 (HPV 18) Protein E7 (E. coli, His)
E7,Protein E7 |
HPV 18 | E. coli |
Human Papilloma Virus type 18 (HPV 18) Protein E7 (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 16.0 kDa and the accession number is P06788. | |||
TMPH-01832 |
Human Papilloma Virus type 16 (HPV 16) Protein E6 (E. coli, His)
E6,Protein E6 |
HPV 16 | E. coli |
Human Papilloma Virus type 16 (HPV 16) Protein E6 (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 23.2 kDa and the accession number is P03126. | |||
TMPK-01466 |
HLA-A*02:01&B2M&HPV 16 E6 (KLPQLCTEL) Tetramer Protein, Human, MHC (His & Avi)
Human papillomavirus type 16,E6,HPV16 |
Human | HEK293 Cells |
Human papillomavirus (HPV) 16 infection is a necessary condition for the pathogenesis and development of cervical cancer. The E6 protein is expressed by the HPV16 E6 gene and promotes malignant phenotype transformation, which is an important mechanism for the occurrence and development of cervical cancer. | |||
TMPH-01830 |
Human Papilloma Virus type 16 (HPV 16) Minor capsid Protein L2 (His & SUMO)
Minor capsid protein L2,L2 |
HPV 16 | E. coli |
Human Papilloma Virus type 16 (HPV 16) Minor capsid Protein L2 (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 66.7 kDa and the accession number is P03107. | |||
TMPK-01467 |
HLA-A*02:01&B2M&HPV 16 E6 (KLPQLCTEL) Monomer Protein, Human, MHC (His & Avi)
HPV16,E6,Human papillomavirus type 16 |
Human | HEK293 Cells |
Human papillomavirus (HPV) 16 infection is a necessary condition for the pathogenesis and development of cervical cancer. The E6 protein is expressed by the HPV16 E6 gene and promotes malignant phenotype transformation, which is an important mechanism for the occurrence and development of cervical cancer. | |||
TMPK-01504 |
HLA-A*02:01&B2M&HPV16 E7 (YMLDLQPET) Tetramer Protein, Human, MHC (His & Avi)
MHC,HPV16,E7 |
Human | HEK293 Cells |
HPV16 E7 protein, one of the primary target proteins in molecular targeted therapy for HPV-induced cervical cancer. The affitoxin, ZHPV16E7 affitoxin384 was generated by fusing the modified Pseudomonas Exotoxin A (PE38KDEL) to the HPV16 E7-specific affibody. | |||
TMPK-01506 |
HLA-A*02:01&B2M&HPV16 E7 (YMLDLQPET) Monomer Protein, Human, MHC (His & Avi)
HPV16,E7,MHC |
Human | HEK293 Cells |
HPV16 E7 protein, one of the primary target proteins in molecular targeted therapy for HPV-induced cervical cancer. The affitoxin, ZHPV16E7 affitoxin384 was generated by fusing the modified Pseudomonas Exotoxin A (PE38KDEL) to the HPV16 E7-specific affibody. | |||
TMPK-01505 |
HLA-A*02:01&B2M&HPV16 E7 (YMLDLQPET) Monomer Protein, Human, MHC (His & Avi), Biotinylated
E7,MHC,HPV16 |
Human | HEK293 Cells |
HPV16 E7 protein, one of the primary target proteins in molecular targeted therapy for HPV-induced cervical cancer. The affitoxin, ZHPV16E7 affitoxin384 was generated by fusing the modified Pseudomonas Exotoxin A (PE38KDEL) to the HPV16 E7-specific affibody. | |||
TMPK-00479 |
AGER Protein, Cynomolgus, Recombinant (His)
AGER,RAGE,SCARJ1 |
Cynomolgus | HEK293 Cells |
The receptor for advanced glycation end products (AGER) is an oncogenic transmembranous receptor up-regulated in various human cancers. AGER promotes proliferation, migration, and inhibits apoptosis of squamous cervical cancer and might function as a tumor promoter in cervical cancer. Our study provides novel evidence for a potential role of AGER in bridging human papillomavirus (HPV)-induced inflammation and cervical cancer. | |||
TMPH-01849 |
Human parvovirus B19 (isolate AU) Non-capsid protein NS-1 (His & SUMO)
NS1,Non-structural protein 1,Initiator protein NS1,NCVP1,Non... |
HPV B19 | E. coli |
Human parvovirus B19 (isolate AU) Non-capsid protein NS-1 (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 44.6 kDa and the accession number is P07298. |