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Search Results for " hl-7702 "
Targets Recommended: Others

3

抑制剂 & 化合物

1

天然产物

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Cat. No. Product Name Target Signaling Pathways
T60748 ZDWX-25

Others Others
ZDWX-25 是 GSK-3β和 DYRK1A 的高效双重抑制剂,它对 SH-SY5Y 和 HL-7702 细胞显示出显著的细胞毒性。ZDWX-25 可用于研究阿尔茨海默症,其对 GSK-3β 的 IC50值为 71 nM。。
T36864 GRP (human) (trifluoroacetate salt)

Gastrin-releasing peptide (GRP) is a neuropeptide that stimulates gastrin release. It binds to (Ki = 300 nM) and stimulates amylase secretion in rat pancreatic AR42J cells (EC50 = 0.3 nM). GRP increases proliferation of human liver carcinoma HepG2 and MHCC97H cells but does not affect the proliferation of normal HL-7702 liver cells at a concentration of 1 nM. In vivo, GRP (0.35 nmol/kg/h) increases both pancreatic exocrine secretion and pancreatic polypeptide (PP) release in rats. It dose-depend...
T84968 Indium (III) thiosemicarbazone 5b

Others Others
Indium (III) thiosemicarbazone 5b is an anticancer compound demonstrating cytotoxicity against various cancer cell lines including A549, MCF-7 breast, cisplatin-resistant MCF-7/DDP breast, and Hl 7702 liver cancer cells, with IC50 values of 2.41, 1.97, 2.11, and 8.95 µM, respectively. It effectively lowers PI3K, Akt, mTOR, P-gp, and GSH levels in MCF-7/DDP cells. In vivo studies show that at a dosage of 2.5 µmol/kg, indium (III) thiosemicarbazone 5b significantly reduces tumor weight and volume ...

化合物

ZDWX-25
Cat.No: T60748
Synonym:
Target: Others
GRP (human) (trifluoroacetate salt)
Cat.No: T36864
Synonym:
Target:
Indium (III) thiosemicarbazone 5b
Cat.No: T84968
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
T3324 Lycorine

Galanthidine,Narcissine,石蒜碱,Amarylline,Belamarine,Licorine,番石榴碱

Apoptosis; Virus Protease; Antibacterial; AChR; Fatty Acid Synthase Apoptosis; Metabolism; Microbiology/Virology; Neuroscience
Lycorine (Narcissine) 是从金眼科植物科中提取的一种天然生物碱。它是一种具有口服活性的SCAP 抑制剂,Kd 值 15.24 nM。它也是黑色素瘤血管生成抑制剂,有用于前列腺癌和代谢疾病的研究潜力。

天然产物

Lycorine
Cat.No: T3324
Synonym: Galanthidine,Narcissine,石蒜碱,Amarylline,Belamarine,Licorine,番石榴碱
Target: Apoptosis, Virus Protease, Antibacterial, AChR, Fatty Acid Synthase
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