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Search Results for " hiv-1 "

Targets Recommended: HIV Protease

548

抑制剂 & 化合物

99

天然产物

2

化合物库

1775

重组蛋白

8

同位素标记化合物

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Cat. No.	Product Name
L1100	蛋白酶抑制剂库		343 compounds
	343 种已知的小分子蛋白酶抑制剂的特有集合，可用于高通量筛选和高内涵筛选；
L7600	趋化因子抑制剂库		59 compounds
	59 种趋化因子或其受体抑制剂的独特集合，可用于高通量筛选和高内涵筛选；

化合物库

蛋白酶抑制剂库

Cat.No: L1100

Compounds: 343

趋化因子抑制剂库

Cat.No: L7600

Compounds: 59

Cat. No.	Product Name	Target	Signaling Pathways
T24141	HIV-1 Inhibitor 18A HIV-1 Inhibitor-18A	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	HIV-1 Inhibitor 18A (HIV-1 Inhibitor-18A) 特异性抑制多种 HIV-1 分离株的进入。
T9039	HIV-1 Nef-IN-1	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	HIV-1 Nef-IN-1 是 HIV-1 Nef 蛋白的抑制剂。它有效地竞争 Nef-SH3Hck 相互作用，Kd 值为 6.7 μM。
TP1149	HIV-1 Rev (34-50) HIV-1 Rev 34-50,HIV-1 rev Protein (34-50)	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	HIV-1 Rev (34-50) (HIV-1 rev Protein (34-50)) 是一种具有抗 HIV-1 活性的 17 个氨基酸多肽。 HIV-1 Rev (34-50) 源自 HIV-1 中 Rev 的 Rev 响应元件结合域。
T67833	HIV-1 inhibitor-54	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	HIV-1 inhibitor-54 是一种有效的 HIV-1 抑制剂，在 MT-4 细胞中对 WT HIV-1 (菌株 IIIB) x 显示出抗 HIV 活性（EC50 ： 32 nM）。HIV-1 inhibitor-54 可用于研究病毒感染。
T9854	HIV-1 inhibitor-6 3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) 是一种有效的HIV-1 pre-mRNA 选择性剪接抑制剂，可以阻断HIV 复制。
TP1809	TAT	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	TAT 源自人免疫缺陷病毒的转录反式激活因子，是一种细胞穿透肽。它可以增加异源蛋白质的产量和溶解度。
T39729	HIV Protease Substrate 1
	HIV Protease Substrate 1 is a fluorogenic compound that offers insights into the enzymatic activity of HIV protease, making it a valuable tool for studying this aspect.
T1883	Des(benzylpyridyl) Atazanavi	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Des(benzylpyridyl) Atazanavi 是 Atazanavir 的 N-脱烷基代谢物 (M1)，一种 HIV 蛋白酶抑制剂。
T11564	HIV-1 inhibitor-3	Others	Others
	HIV-1 inhibitor-3 is an HIV infection inhibitor.
T11566	HIV-1 integrase inhibitor	Others	Others
	Hiv-1 integrase inhibitor is an effective anti-HIV drug.
T40719	(Cys47)-HIV-1 tat Protein (47-57) (Cys47)-HIV-1 tat Protein (47-57)
	(Cys47)-HIV-1 tat Protein (47-57) possesses membrane translocation functionality and can serve as a surface derivatization agent for magnetic pharmaceuticals, thereby enhancing their uptake into specific target cells.
TP1776	HIV-1 TAT 48-60
	HIV-1 TAT (48-60) is a cell-penetrating peptide derived from the human immunodeficient virus (HIV)-1 Tat protein residue 48-60. This is one of the cell-penetrating peptides generated from the human immunodeficient virus -1 Tat protein residue 48-60.
T60742	HIV-1 integrase inhibitor 8	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	HIV-1 integrase inhibitor 8 是一种 HIV-1 整合酶抑制剂，整合是HIV 复制的必要步骤。
T11567	HIV-1 integrase inhibitor 3	Others	Others
	HIV-1 integrase inhibitor 3 is an HIV-1 integrase strand transfer (INST) inhibitor (IC50: 2.7 nM).
T11565	HIV-1 integrase inhibitor 7	Others	Others
	HIV-1 integrase inhibitor 7 is a potent HIV-1 integrase inhibitor (IC50: 33.3 nM).
T11568	HIV-1 integrase inhibitor 4	Others	Others
	HIV-1 integrase inhibitor 4 is an HIV-1 integrase strand transfer (INST) inhibitor (IC50: 3.7 nM).
T9212	IMB-301	Others; HIV Protease	Microbiology/Virology; Others; Proteases/Proteasome
	IMB-301是根据 hA3G 模型通过虚拟筛选的一种小分子抑制剂。
T4182	lavendustin B 薰草菌素B	Tyrosinase; transporter; HIV Protease	Metabolism; Microbiology/Virology; Proteases/Proteasome
	Lavendustin B 是一种酪氨酸激酶抑制剂，是 HIV-1 整合酶 (IN) 与其同源细胞辅助因子、晶状体上皮衍生生长因子 (LEDGF/p75) 相互作用的抑制剂。
T15371	Gardiquimod	TLR; HIV Protease	Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
	Gardiquimod 可抑制巨噬细胞和活化的外周血单个核细胞的HIV-1感染。它是一种咪唑喹啉类似物，是一种 TLR7/8 激动剂。
T16276	NBD-556	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	NBD-556是一种 CD4 模拟物，识别 HIV-1 包膜蛋白 gp120 并诱导 gp120 重组，类似于 CD4 结合，可阻断 gp120-CD4 的相互作用。
T12715	Reverse transcriptase-IN-1	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Reverse transcriptase-IN-1 是一种二芳基苯并嘧啶类似物，是一种有效的 HIV-1 非核苷类逆转录酶抑制剂，IC50 为 13.7 nM。
T11465	Lenacapavir GS-6207	Others; HIV Protease	Microbiology/Virology; Others; Proteases/Proteasome
	Lenacapavir (GS-6207) 是一种有效的靶向衣壳的 HIV 复制抑制剂。 Lenacapavir 在 MT-4 细胞中显示出抗 HIV 活性，EC50 为 100 pM。
T8233	BRD3308	Apoptosis; HIV Protease; HDAC	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Microbiology/Virology; Proteases/Proteasome
	BRD3308 是一种高选择性的HDAC3抑制剂，IC50为 54 nM。它可激活HIV-1转录并破坏HIV-1潜伏期。它抑制由炎性细胞因子或糖脂毒性应激诱导的胰腺 β 细胞凋亡，并增加功能性胰岛素释放。
T28578	Ro24-7429 Ro 24-7429,Ro-24-7429,Ro 247429	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Ro24-7429 是一种有效的口服活性 HIV-1 反式激活蛋白 Tat 拮抗剂和一种矮小相关转录因子 1 的抑制剂。Ro24-7429 具有抗 HIV、抗纤维化和抗炎作用。
T9063	Clathrin-IN-1	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Clathrin-IN-1 是一种网格蛋白抑制剂，可通过与网格蛋白的末端域相关联来抑制网格蛋白介导的内吞作用，有潜力用于抗癌的研究。
T20062	Thiamine disulfide 二硫化硫胺,TDS,Daiomin,Algoneurina	HIV Protease; Endogenous Metabolite	Metabolism; Microbiology/Virology; Proteases/Proteasome
	Thiamine disulfide (Algoneurina) 是一种存在于食物中的维生素，可作为膳食补充剂和药物生产。它还充当许多中枢代谢酶的辅助因子。
T6246	Cobicistat Tybost,GS-9350,考西司他	P450; HIV Protease	Metabolism; Microbiology/Virology; Proteases/Proteasome
	Cobicistat (GS-9350) 是一种细胞色素酶P450 3A 的选择性抑制剂，IC50值为30-285 nM。它是一种药代动力学增强剂，可增强抗 HIV 药物的吸收。
T11538	Hck-IN-1	HIV Protease; Src; Hck	Angiogenesis; Microbiology/Virology; Proteases/Proteasome; Tyrosine Kinase/Adaptors
	Hck-IN-1 是二苯基吡唑啉化合物，选择性的 Nef 依赖性 Hck 抑制剂。它是广泛的 HIV-1 Nef 直接拮抗剂，对于野生型 HIV-1 复制的IC50为 100-300 nM。它结合口袋残基 Asn126，具有抗逆转录病毒活性。
T6420	BMS-707035 N-[(4-氟苯基)甲基1,6-二氢-5-羟基-1-甲基-6-氧代-2-(四氢-1,1-二氧-2H-1,2-噻嗪-2-基)-4-嘧啶甲酰胺	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	BMS707035是一种 HIV-1 整合酶抑制剂，IC50为15 nM。
T9223	RO-0335	Reverse Transcriptase	Microbiology/Virology
	RO-0335 是新高效二苯醚非核苷逆转录酶抑制剂。它 (IC50= 1.1 nM) 可以抑制Wt HIV-1病毒，对 92% 的 NNRTI 耐药临床分离株具有保留活性 (IC50<100 nM)。
T3199	PTACH NCH-51,Cpd 51	HIV Protease; HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair; Microbiology/Virology; Proteases/Proteasome
	PTACH (Cpd 51) 是一种有效的 HDAC 抑制剂，对 HDAC1，HDAC4和 HDAC6的 IC50分别为 48 nM，32 nM 和 41 nM。PTACH 对多种癌细胞具有强大的生长抑制作用 (EC50为 1.1-9.1 µM)。
T27030	CK176 HIV-1 inhibitor-34,HIV-1 inhibitor 34,CK 176,CK-176,HIV-1 inhibitor34	Others	Others
	CK176 is a capsid targeted inhibitor of HIV-1 replication. CK176 shows an 11-fold improvement over I-XW-053 in blocking HIV-1 replication in primary human peripheral blood mononuclear cells (PBMCs).
T11281L	FGI-106 tetrahydrochloride	Virus Protease; HCV Protease; Influenza Virus; HIV Protease	Microbiology/Virology; Proteases/Proteasome
	FGI-106 tetrahydrochloride 对多种病毒具有抑制活性，有抗埃博拉病毒，裂谷病毒和登革热病毒的 EC50分别为 100 nM，800 nM 和 400-900 nM，抑制非失血性发热病毒HCV 和HIV-1的EC50分别为 200 nM 和 150 nM 。
T6255	Bromosporine	Epigenetic Reader Domain; CDK	Cell Cycle/Checkpoint; Chromatin/Epigenetic
	Bromosporine 是广谱 BRD2/4/9 和 CECR2 溴结构域抑制剂，IC50为0.41、0.29、0.122和0.017 μM。
T0100L	Atazanavir Zrivada,Reyataz,Latazanavir,阿扎那韦,BMS-232632	P450; SARS-CoV; HIV Protease; P-gp	Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience; Proteases/Proteasome
	Atazanavir (BMS-232632) 是一种高选择性的HIV-1蛋白酶抑制剂，可研究艾滋病毒感染。它也是SARS-CoV 3CLpro 的抑制剂，IC50为 3.49 μM。它是CYP3A4的底物和抑制剂，也是P-糖蛋白的抑制剂和诱导剂。
T7212	Delavirdine mesylate U 90152 (mesylate),BHAP-U 90152 (mesylate),Delavirdine (mesylate)	HIV Protease; Reverse Transcriptase	Microbiology/Virology; Proteases/Proteasome
	Delavirdine mesylate (BHAP-U 90152(mesylate)) 是一种口服活性非核苷逆转录酶抑制剂。它抑制 HIV-1 病毒复制，可以用于艾滋病的相关研究。它选择性地抑制 HIV-1 逆转录酶，其选择性超过 DNA 聚合酶 α 和 DNA 聚合酶 δ 。
T76502	HIV-1, HIV-2 Protease Substrate
	HIV-1,HIV-2Protease Substrate 是HIV-1，HIV-2蛋白酶的底物。HIV-1和HIV-2蛋白酶底物结合残基有 4 个保守取代残基。
T15483	LEDGIN6 HIV-1 integrase inhibitor 2	Others	Others
	HIV-1 integrase inhibitor 2 is used for the treatment of human immunodeficiency virus (HIV) infection.
T11074	Dolutegravir intermediate-1 1-(2,2-dimethoxyethyl)-5-methoxy-6-methoxycarbonyl-4-oxopyridine-3-carboxylic acid,1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Dolutegravir intermediate-1 (1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid) 是 Dolutegravir 的一种新合成中间体。它是一种整合酶抑制剂，有潜力研究人类免疫缺陷病毒 (HIV)-1 感染。
T7700	Lersivirine 3-氰基-5-[[3,5-二乙基-1-(2-羟基乙基)-1H-吡唑-4-基]氧基]苯腈,Lersivirine(UK 453061),UK-453061	HIV Protease; Reverse Transcriptase	Microbiology/Virology; Proteases/Proteasome
	Lersivirine (UK-453061) 是非核苷逆转录的抑制剂 (NNRTI)，有效抑制 NNRTI 耐药病毒。它对野生型人类免疫缺陷病毒和临床相关 NNRTI 耐药菌株显示出强大的抗逆转录病毒活性。
T62319	HIV-1 inhibitor-44	Others	Others
	HIV-1 inhibitor-44 (compound 11l) 是一种 HIV-1 逆转录酶抑制剂，表现出抗野生型 HIV-1 菌株的活性 (EC50: 0.209 μM)。
T62353	HIV-1 inhibitor-33	Others	Others
	HIV-1 inhibitor-33 (compound 5n) 是一种有效的、选择性的 HIV-1 抑制剂，作用于 HIV-1 (EC50: 8.6 nM)、MT-4 细胞 (CC50: 18 μM)。HIV-1 inhibitor-33 能够用于研究艾滋病。
T62287	HIV-1 inhibitor-42	Others	Others
	HIV-1 inhibitor-42 (compound 5b) 是一种 HIV-1 的有效抑制剂 (IC50: 0.06 μM)。HIV-1 inhibitor-42 能够抑制 HIV-1 RT RNA 依赖性 DNA 聚合酶 (IC50: 0.518 μM) 和 DNA 依赖性 DNA 聚合酶 (IC50: 0.072 μM) 。
T61134	HIV-1 inhibitor-36	Others	Others
	HIV-1 inhibitor-36 (Compound 2) is a potent HIV-1 inhibitor with significant potential as a novel latency reversing agent [1].
T63687	HIV-1 inhibitor-18	Others	Others
	HIV-1 inhibitor-18 是 HIV-1 衣壳的有效抑制剂，能够作用于 HIV-1 NL4-3 病毒株 (EC50: 5.14 μM)，并表现出一定的细胞毒性 (MT-4CC50>9.51)。
T64009	HIV-1 inhibitor-23	Others	Others
	HIV-1 inhibitor-23 是 HIV-1 非核苷逆转录酶的高效抑制剂，能够作用于野生型 HIV-1 (EC50: 24.9 nM) 和突变病毒株 K103N (EC50: 10.4 nM)。HIV-1 inhibitor-23 的细胞毒性较低 (CC50> 221 μM)，并具有良好的体外微粒体稳定性。
T78749	HIV-1 inhibitor-57	Others	Others
	HIV-1 inhibitor-57（Compound 12g）是抗HIV药物。该化合物对野生型及五种常见NNRTI耐药HIV-1株均表现出抗病毒活性，具有0.024至0.0010 μM的EC 50值。HIV-1 inhibitor-57能够与HIV-1RT的结合位点附近残基形成附加相互作用。
T60342	HIV-1 inhibitor-47	Others	Others
	HIV-1 inhibitor-47 is a compound that effectively inhibits HIV-1 by preventing the vif-dependent degradation of human APOBEC3G. It has a notable inhibition effect, with an IC50 value of 14.33 μM. Additionally, HIV-1 inhibitor-47 is involved in the synthesis of derivatives of 1-(2-pyrimidinyl)piperazine, which have the potential to exhibit antianxiety, antidepressant, and antipsychotic effects [1] [2] [3].
T72565	HIV-1 inhibitor-52	Others	Others
	HIV-1inhibitor-52 是高效广谱HIV-1活性抑制剂，具备对 WT HIV-1、HIV-1 V370A、HIV-1 ΔV370、HIV-1 V362I/V370A、HIV-1 T332S/V362I/prR41G、HIV-1 A326T/V362I/V370A、和HIV-1 R361K/V362I/L363M 等变异株的强效抑制作用，其EC50值范围为 1.6 nM至6.4 nM。
T63813	HIV-1 inhibitor-39	Others	Others
	HIV-1 inhibitor-39 是 HIV-1 的有效抑制剂 (EC50>112.88 μM)。 HIV-1 inhibitor-39 具有抗 RT (HIV-1 逆转录酶) 作用 (IC50: 15.75 μM)。HIV-1 inhibitor-39 对 MT-4 细胞表现出细胞毒性 (CC50: 112.9 μM)。

化合物

HIV-1 Inhibitor 18A

Cat.No: T24141

Synonym: HIV-1 Inhibitor-18A

Target: HIV Protease

HIV-1 Nef-IN-1

Cat.No: T9039

Target: HIV Protease

HIV-1 Rev (34-50)

Cat.No: TP1149

Synonym: HIV-1 Rev 34-50,HIV-1 rev Protein (34-50)

Target: HIV Protease

HIV-1 inhibitor-54

Cat.No: T67833

Target: HIV Protease

HIV-1 inhibitor-6

Cat.No: T9854

Synonym: 3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-

Target: HIV Protease

Cat.No: TP1809

Target: HIV Protease

HIV Protease Substrate 1

Cat.No: T39729

Des(benzylpyridyl) Atazanavi

Cat.No: T1883

Target: HIV Protease

HIV-1 inhibitor-3

Cat.No: T11564

Target: Others

HIV-1 integrase inhibitor

Cat.No: T11566

Target: Others

(Cys47)-HIV-1 tat Protein (47-57)

Cat.No: T40719

Synonym: (Cys47)-HIV-1 tat Protein (47-57)

HIV-1 TAT 48-60

Cat.No: TP1776

HIV-1 integrase inhibitor 8

Cat.No: T60742

Target: HIV Protease

HIV-1 integrase inhibitor 3

Cat.No: T11567

Target: Others

HIV-1 integrase inhibitor 7

Cat.No: T11565

Target: Others

HIV-1 integrase inhibitor 4

Cat.No: T11568

Target: Others

Cat.No: T9212

Target: Others, HIV Protease

Cat.No: T4182

Synonym: 薰草菌素B

Target: Tyrosinase, transporter, HIV Protease

Cat.No: T15371

Target: TLR, HIV Protease

Cat.No: T16276

Target: HIV Protease

Reverse transcriptase-IN-1

Cat.No: T12715

Target: HIV Protease

Cat.No: T11465

Synonym: GS-6207

Target: Others, HIV Protease

Cat.No: T8233

Target: Apoptosis, HIV Protease, HDAC

Cat.No: T28578

Synonym: Ro 24-7429,Ro-24-7429,Ro 247429

Target: HIV Protease

Cat.No: T9063

Target: HIV Protease

Thiamine disulfide

Cat.No: T20062

Synonym: 二硫化硫胺,TDS,Daiomin,Algoneurina

Target: HIV Protease, Endogenous Metabolite

Cat.No: T6246

Synonym: Tybost,GS-9350,考西司他

Target: P450, HIV Protease

Cat.No: T11538

Target: HIV Protease, Src, Hck

Cat.No: T6420

Synonym: N-[(4-氟苯基)甲基1,6-二氢-5-羟基-1-甲基-6-氧代-2-(四氢-1,1-二氧-2H-1,2-噻嗪-2-基)-4-嘧啶甲酰胺

Target: HIV Protease

Cat.No: T9223

Target: Reverse Transcriptase

Cat.No: T3199

Synonym: NCH-51,Cpd 51

Target: HIV Protease, HDAC

Cat.No: T27030

Synonym: HIV-1 inhibitor-34,HIV-1 inhibitor 34,CK 176,CK-176,HIV-1 inhibitor34

Target: Others

FGI-106 tetrahydrochloride

Cat.No: T11281L

Target: Virus Protease, HCV Protease, Influenza Virus, HIV Protease

Cat.No: T6255

Target: Epigenetic Reader Domain, CDK

Cat.No: T0100L

Synonym: Zrivada,Reyataz,Latazanavir,阿扎那韦,BMS-232632

Target: P450, SARS-CoV, HIV Protease, P-gp

Delavirdine mesylate

Cat.No: T7212

Synonym: U 90152 (mesylate),BHAP-U 90152 (mesylate),Delavirdine (mesylate)

Target: HIV Protease, Reverse Transcriptase

HIV-1, HIV-2 Protease Substrate

Cat.No: T76502

Cat.No: T15483

Synonym: HIV-1 integrase inhibitor 2

Target: Others

Dolutegravir intermediate-1

Cat.No: T11074

Synonym: 1-(2,2-dimethoxyethyl)-5-methoxy-6-methoxycarbonyl-4-oxopyridine-3-carboxylic acid,1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid

Target: HIV Protease

Cat.No: T7700

Synonym: 3-氰基-5-[[3,5-二乙基-1-(2-羟基乙基)-1H-吡唑-4-基]氧基]苯腈,Lersivirine(UK 453061),UK-453061

Target: HIV Protease, Reverse Transcriptase

HIV-1 inhibitor-44

Cat.No: T62319

Target: Others

HIV-1 inhibitor-33

Cat.No: T62353

Target: Others

HIV-1 inhibitor-42

Cat.No: T62287

Target: Others

HIV-1 inhibitor-36

Cat.No: T61134

Target: Others

HIV-1 inhibitor-18

Cat.No: T63687

Target: Others

HIV-1 inhibitor-23

Cat.No: T64009

Target: Others

HIV-1 inhibitor-57

Cat.No: T78749

Target: Others

HIV-1 inhibitor-47

Cat.No: T60342

Target: Others

HIV-1 inhibitor-52

Cat.No: T72565

Target: Others

HIV-1 inhibitor-39

Cat.No: T63813

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T5783	Rosamultin 野蔷薇苷,罗莎白素	Antioxidant; HIV Protease	Microbiology/Virology; oxidation-reduction; Proteases/Proteasome
	Rosamultin 是从Potentilla anserina L 分离的 19 α-羟基型三萜。它抑制 HIV-1 蛋白酶，具有抗氧化、抗炎和镇痛作用。
TN1103	Diphyllin 山荷叶素,二叶草素	ATPase; Proton pump; Influenza Virus; HIV Protease	Membrane transporter/Ion channel; Microbiology/Virology; Proteases/Proteasome
	Diphyllin 是一种从Justicia procumbens 中分离的芳基萘木脂素，是HIV-1的有效抑制剂，IC50 为 0.38 μM。它是V-ATPase 抑制剂，IC50值为 17 nM，可抑制人破骨细胞中的溶酶体酸化。它抑制NO 产生，IC50值为 50 μM ，具有抗癌和抗炎活性。
T6S2391	L-Chicoric Acid (-)-Chicoric acid,trans-Caffeoyltartaric acid,Chicoric acid,L-菊苣酸,dicaffeoyltartaric acid,菊苣酸	Others; HIV Protease	Microbiology/Virology; Others; Proteases/Proteasome
	L-Chicoric Acid (trans-Caffeoyltartaric acid) 是一种二咖啡酰酒石酸，是一种选择性可逆的 HIV-1 整合酶抑制剂，IC50约为 100 nM。它还可抑制 HIV-1 复制。
T4962	Zingibroside R1 Ginsenoside Z-R1,姜状三七皂苷R1,姜状三七苷R1	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Zingibroside R1 (Ginsenoside Z-R1) 是分离自Panax japonicasC. A. Meyer 根部的一种三萜皂苷，有HIV-1、抗肿瘤和抗血管生成活性。它对 EAT 细胞的 2-脱氧-D-葡萄糖的摄取具有抑制作用，IC50值为91.3 μM。
T22468	1-Deoxymannojirimycin hydrochloride	Others; Influenza Virus; HIV Protease	Microbiology/Virology; Others; Proteases/Proteasome
	1-Deoxymannojirimycin hydrochloride 是一种选择性的 α1,2-甘露糖苷酶抑制剂，IC50值为 20 μM。它还抑制 HIV-1 毒株，抗病毒活性较差。
T0200	α-Lipoic Acid Thioctic acid,DL-α-Lipoic acid,(±)-α-Lipoic acid,α-硫辛酸,硫辛酸	Apoptosis; NF-κB; HIV Protease; Mitochondrial Metabolism; Endogenous Metabolite	Apoptosis; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome
	α-Lipoic Acid (DL-α-Lipoic acid) 是线粒体酶复合物的重要辅助因子，是一种抗氧化剂，可抑制NF-κB 依赖性的HIV-1LTR 活化。它还可诱导内质网应激介导的肝癌细胞凋亡。
T4S1383	Escin IA Aescin IA,Escin IA;Aescin IA,Escin IA	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Escin IA (Escin IA;Aescin IA);Aescin IA 是从马蹄中七叶树分离出的一种三萜皂苷，抑制HIV-1蛋白酶，IC50值为 35 μM。它具有抗 TNBC 转移活性，其作用机制涉及通过下调 LOXL2 表达抑制上皮-间质转化过程。
T4S1718	Punicalin	HBV; HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Punicalin 是从Punica granatumL. 或Terminalia catappaL. 的叶子中分离的，一种可水解的单宁，具有抗炎活性。它是一种抗乙型肝炎病毒药物。
T3730	Methyl gallate NSC 363001,Gallicin,Gallic acid methyl ester,Gallincin,没食子酸甲酯	Reactive Oxygen Species; HIV Protease; Reverse Transcriptase; Antibacterial	Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome
	Methyl gallate (Gallincin) 是具有抗氧化，抗癌和抗炎活性的植物酚类。它也可抑制细菌活性。它还具有抗HIV-1和HIV-1酶的抑制活性。
T4S1387	Isoescin IA 七叶皂苷C,异七叶皂苷 IA	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Isoescin IA 是一种从七叶树种子中分离出来的三萜皂苷。它具有抗HIV-1蛋白酶活性。
T2S0223	Isosinensetin 异橙黄酮,6-Demethoxynobiletin	Antioxidant; HIV Protease; Antibacterial; P-gp	Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience; oxidation-reduction; Proteases/Proteasome
	Isosinensetin (6-Demethoxynobiletin) 是从青皮中提取的一种甲氧基黄酮，具有抗氧化和抑制 HIV-1 蛋白酶的活性。
TN2283	Tripterifordin	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Tripterifordin 在 H9 淋巴细胞中显示出抗 HIV 复制活性，EC50值为 3100 nM。
TN5263	1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one Xanthohumol,黄腐酚	Apoptosis; BCL; PARP; HCV Protease; IAP; Caspase; HIV Protease; NMDAR; p53	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Microbiology/Virology; Neuroscience; Proteases/Proteasome
	1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one (Xanthohumol) 是一种从蛇麻草中提纯的具有多种生物功能的天然产物。黄腐酚对 HIV-1 有效，可能是一种有趣的先导化合物。它可能代表一种用于 HIV-1 感染的新型化疗药物。
T5782	Bevirimat YK FH312,MPC-4326,PA-457,贝韦立马	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Bevirimat (PA-457) 是一种 HIV-1 成熟抑制剂，可在病毒体成熟过程中阻断 Gag 衣壳 (CA) 前体 CA-SPI 裂解为成熟的 CA 蛋白。
T4S1521	1,4-Dicaffeoylquinic acid 1,4-二咖啡酰奎宁酸,洋蓟素	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	1,4-Dicaffeoylquinic acid 是一种苯丙素类物质，从苍耳子中获得，可以减少 LPS 诱导的 TNF-α 的生成，具有抗炎活性。
T3323	Ursonic Acid CCRIS 7123,NSC4060,熊果酮酸,Prunol,3-Ketoursolic acid,Malol,TOS-BB-0966	Apoptosis; HIV Protease; Endogenous Metabolite	Apoptosis; Metabolism; Microbiology/Virology; Proteases/Proteasome
	Ursonic Acid (TOS-BB-0966) 是一种天然三萜酸，属于熊果烷三萜类，其结构基于五环熊果烷骨架。它具有作为 HIV-1 蛋白酶抑制剂的潜力。
TJS1779	Protosappanin A 原苏木素A,PTA	NADPH-oxidase; IL Receptor; IκB/IKK; TNF; NF-κB; TLR; ROS; COX; HIV Protease; JAK; NO Synthase; STAT	Angiogenesis; Apoptosis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Microbiology/Virology; Neuroscience; NF-κB; Proteases/Proteasome; Stem Cells
	Protosappanin A (PTA) 是从苏木中分离得到的免疫抑制成分和主要联苯化合物，通过下调 JAK2和 STAT3的磷酸化，抑制 JAK2/STAT3依赖的炎症通路。
T2S1158	4,5-Dicaffeoylquinic acid 3,4-Dicaffeoylquinic acid,异绿原酸C(4,5),Isochlorogenic acid C	Others; HBV; Endogenous Metabolite	Metabolism; Microbiology/Virology; Others
	4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) 是一种天然产物，有抗病毒、抗肝毒性活性。
T4537	Cholic acid sodium 胆酸钠,[胆酸钠],SodiumCholate	HIV Protease; Endogenous Metabolite	Metabolism; Microbiology/Virology; Proteases/Proteasome
	Cholic acid sodium (SodiumCholate) 是肝脏中产生的主要胆汁酸，通常与牛磺酸或甘氨酸结合，有助于脂肪吸收和胆固醇排泄。
TL0006	Cichoric Acid 菊苣酸,Dicaffeoyltartaric acid,Chicoric Acid	Reactive Oxygen Species; HIV Protease	Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome
	Cichoric Acid (Dicaffeoyltartaric acid) 是一种天然化合物，具有抗氧化作用。
T6841	Fumagillin NSC9168,烟曲霉素,Amebacilin	Others; HIV Protease; Antibiotic; Parasite	Microbiology/Virology; Others; Proteases/Proteasome
	Fumagillin (Amebacilin) 由烟曲霉菌中提取的一种抗菌药，有抗阿米巴活性。它通过抑制 HIV-1 viral protein R 活性来抑制 HIV‐1感染。
T4S0295	Apigenin 7-glucoside 波斯菊,Cosmetin,Cosmosiin,Cosmosioside,Apigenin-7-O-β-D-glucopyranoside,芹甙元-7-葡萄糖苷,Thalictiin,Apigetrin	Reactive Oxygen Species; HIV Protease	Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome
	Apigenin 7-glucoside (Cosmosiin) 是一种 ROS 清除剂，具有抗增殖、抗氧化作用。
T8689	Chloroquine CQ,氯喹	SARS-CoV; TLR; HIV Protease; Antibiotic; Parasite; Autophagy	Autophagy; Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
	Chloroquine 是一种 Toll 样受体抑制剂，可以抑制自噬。Chloroquine 具有抗疟疾和抗炎活性，广泛用于治疗疟疾和类风湿性关节炎。Chloroquine 还具有抗 SARS-CoV-2 (COVID-19) 活性、抗 HIV-1 活性。
T2930	α-Lipoic Acid Lipoic acid,Alphalipoic acid,硫辛酸	NF-κB; HIV Protease; Mitochondrial Metabolism; Endogenous Metabolite	Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome
	α-Lipoic Acid (Alphalipoic acid) 抑制 NF-κB 依赖性 HIV-1 LTR 活化。 α-硫辛酸诱导内质网 (ER) 应激介导的肝癌细胞凋亡。α-硫辛酸是一种抗氧化剂，是线粒体酶复合物的重要辅助因子。
T3122	Fangchinoline Tetrandrine B,防己诺林碱,(+)-Limacine,Hanfangichin B,防己醇灵,(+)-Fangchinoline	Apoptosis; FAK; HIV Protease; Autophagy	Angiogenesis; Apoptosis; Autophagy; Cytoskeletal Signaling; Microbiology/Virology; Proteases/Proteasome; Tyrosine Kinase/Adaptors
	Fangchinoline (Tetrandrine B) 是从Stephaniatetrandra 中分离出来的，一种具有广泛生物学活性的天然产物。它是新型HIV-1抑制剂，通过损害 gp160 蛋白水解过程来抑制 HIV-1 复制。它靶向Focal adhesion kinase (FAK)并抑制肿瘤细胞中 FAK 介导的的信号传导途径。
TN1622	Ermanin 堪非醇3,4'-二-O-甲醚	NOS; Influenza Virus; COX; HIV Protease; Antibacterial; Antibiotic	Immunology/Inflammation; Microbiology/Virology; Neuroscience; Proteases/Proteasome
	Ermanin 是一种从 Tanacetum microphyllum 中分离出来的类黄酮。Ermanin抑制血小板聚集，具有抗结核和抗病毒/细菌特性。Ermanin 可抑制 iNOS 和 COX-2 的表达，从而具有抗炎活性。Ermanin 可能具有抗 HIV-1 活性。Ermanin 在较低浓度下可有效地抑制 Dione juno 幼虫。
T5S2017	Ingenol (-)-Ingenol,巨大戟二萜醇,巨大戟醇	PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	Ingenol ((-)-Ingenol) 是一种PKC 激活剂，Ki 值为 30 μM，具有抗肿瘤活性。从 Ingenol 酯中配制新的衍生物可能是开发新的先导化合物以重新激活潜伏 HIV 的创新方法。Ingenol mebutate 是治疗光化性角化病的有效方法。
TN1059	Ganoderic acid B	IL Receptor; HIV Protease; JAK; STAT	Angiogenesis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Microbiology/Virology; Proteases/Proteasome; Stem Cells
	Ganoderic acid B 是从灵芝中分离的一种三萜类天然产物。它是端粒酶抑制剂，抑制 Epstein-Barr 病毒抗原的活化。它是 HIV-1 蛋白酶抑制剂。
TN1727	Helichrysetin 4,2',4'-三羟基-6'-甲氧基查耳酮,蜡菊亭	Apoptosis; HIV Protease	Apoptosis; Microbiology/Virology; Proteases/Proteasome
	Helichrysetin 是从豆蔻果实中分离出的一种天然产物，是一种 DNA 结合抑制剂，可抑制原位导管癌DCIS 的形成。它抑制细胞生长，可诱导 A549 细胞凋亡。
T4839	Ac-Ala-OH N-Acetylalanine,N-Acetyl-L-alanine,N-乙酰-L-丙氨酸	Others; Endogenous Metabolite	Metabolism; Others
	Ac-Ala-OH (N-Acetyl-L-alanine) 是鸟嘌呤核苷酸结合蛋白G(I)/G(S)/G(O) γ -2亚基、髓鞘碱性蛋白、GTP-结合核蛋白 Ran、原肌球蛋白 α - 4链、HIV-1 Rev 结合蛋白2、Xaa-Pro 二肽酶、胸腺酶 β -10、肌动蛋白样蛋白3、丙氨酸转氨酶、丝氨酸/苏氨酸蛋白磷酸酶PP1 - β催化亚基、10 kda 热休克蛋白(线粒体)、钙调蛋白和 β -1-syntrophin 的底物。
T5S1103	Isoliensinine 异莲心碱,Isoliensinin	Apoptosis; Antioxidant	Apoptosis; oxidation-reduction
	Isoliensinine (Isoliensinin) 是从水芙蓉种子胚中提取的一种双苄基异喹啉生物碱，能诱导三阴性乳腺癌细胞凋亡，具有抗氧化、抗炎、抗癌活性。
T0474	Erythromycin ethylsuccinate EES,琥乙红霉素	ribosome; HIV Protease; Antibacterial; Antibiotic; Autophagy	Autophagy; Microbiology/Virology; Proteases/Proteasome
	Erythromycin ethylsuccinate (EES) 是一种由红链霉菌产生的大环内酯类抗生素，有潜力用于多种细菌感染。它具有抗 HIV-1病毒活性。
T0966	Sennoside A 番泻苷A,NSC 112929,番泻苷 A	MAO; HIV Protease	Metabolism; Microbiology/Virology; Neuroscience; Proteases/Proteasome
	Sennoside A (NSC-112929) 是在番泻叶的叶子和豆荚中大量发现的蒽醌苷，抑制 HIV-1 复制。
T3321	Oleanonic acid 3-Oxooleanolic acid,3-Oxoolean-12-en-28-oic Acid,Oleanonic Acid,齐墩果酮酸,3-Ketooleanolic Acid	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Oleanonic acid (3-Ketooleanolic Acid) 是一种三萜，可以抑制 HIV-1 对细胞的感染。它具有保肝作用，并具有抗肿瘤和抗病毒特性。
T16791	Rottlerin Mallotoxin,NSC 56346,粗糠柴苦素,NSC 94525	CaMK; Apoptosis; Others; HIV Protease; PKA; PKC; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling; Microbiology/Virology; Neuroscience; Others; Proteases/Proteasome; Tyrosine Kinase/Adaptors
	Rottlerin (NSC-56346) 是一种从Mallotus Philippinensis 中得到的天然产物，是 PKC 的特异性抑制剂，抑制HIV-1整合和狂犬病病毒感染。它通过活化 caspase 3 诱导细胞凋亡.
T5429	Theaflavin 3,3'-digallate 茶黄素-3,3'-双没食子酸,8-Gingerol,TFDG	Virus Protease; Antioxidant; HIV Protease; HSV	Microbiology/Virology; oxidation-reduction; Proteases/Proteasome
	Theaflavin 3,3'-digallate (8-Gingerol) 是一种寨卡病毒蛋白酶抑制剂，IC50为 2.3 μM。它直接与 ZIKVpro 结合并抑制 ZIKV 复制，可抑制 gp41 和 NS2B-3 蛋白酶的活性，并具有抗 HSV 和 HIV-1病毒活性。它是红茶中的主要多酚，有抗肿瘤作用。
T2S0731	Trilobatin 三叶苷,三叶甙,P-Phlorizin	Amylase	Metabolism
	Trilobatin (P-Phlorizin) 是源自Lithocarpus polystachyusRehd 的甜味剂，是一种HIV-1抑制剂，靶向 Gp41 包膜蛋白，具有神经保护作用。它还是SGLT1/2抑制剂，可选择性诱导人肝母细胞瘤细胞增殖。
T4S0797	Berberine 小檗碱,Berberin,Umbellatine,黄连素	Reactive Oxygen Species; Topoisomerase; Endogenous Metabolite; Antibacterial; Antibiotic; Autophagy	Autophagy; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
	Berberine (Umbellatine) 属于生物碱类天然产物，可以激活 AMPK、抑制 DNA 拓扑异构酶、诱导 ROS 生成。Berberine 具有抗肿瘤、抗菌、降血糖、降血脂等生物学活性。
T2830	Betulinic acid 白桦脂酸,桦木酸,ALS-357,Lupatic acid,Betulic acid	Apoptosis; Mitophagy; NF-κB; HIV Protease; Topoisomerase; Endogenous Metabolite; Aminopeptidase; Autophagy	Apoptosis; Autophagy; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome
	Betulinic acid (ALS-357) 是从白桦树皮中分离出来的一种五环三萜类天然产物，是真核细胞拓扑异构酶 I 的抑制剂，IC50值为 5 μM，具有抗逆转录病毒、抗疟疾、抗癌和抗炎特性。
TN5675	Ganomycin I
	Ganomycin I inhibits the activity of HIV-1 protease.
TN5012	Shizukaol C	HIV Protease; Antifection	Microbiology/Virology; Proteases/Proteasome
	1. Shizukaol C shows anti-HIV-1 replication activities in both wild-type HIV-1 and two NNRTIs-resistant strains. <br/> 2. Shizukaol C has significant cytotoxicities against C8166 cells. <br/>
TN4555	Methyl salvionolate A	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Methyl salvionolate A has anti-HIV-1 activity.
TN6541	Cleomiscosin B
	Cleomiscosins A, B and C exhibit liver-protective properties. Cleomiscosin B shows the potent anti-HIV-1 activity in vitro and also has protective effects on MT4 cells infected by HIV-1(IIIB).
T25445	Ganoderiol B
	Ganoderiol B is a moderately active HIV-1 PR inhibitor (IC50: 0.17-0.23 mM).
TN7388	Ganoderic acid GS-2	Others	Others
	Ganoderic acid GS-2 inhibits the activity of the human immunodeficiency virus-1 (HIV-1) protease.
T73758	Glycolithocholic acid 3-sulfate	Others	Others
	Glycolithocholic acid 3-sulfate (SLCG) 为一种胆汁酸衍生物及甘胆酸的代谢产物，具有抑制HIV-1复制的作用。该化合物在HIV感染和胆囊疾病的研究中有潜在应用价值。
TN4820	Pre-schisanartanin B	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Pre-schisanartanin B has cytotoxicity, it also has anti-HIV-1 activity.
T75553	Salvianan A	Others	Others
	1,6,11-Trimethyl-1,2-dihydrofuro[2',3':1,2]phenanthro[4,3-d]oxazole (compound 1) 是一种有效的抗HIV-1剂。
TN4835	Przewalskin	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Przewalskin A and Przewalskin B showed modest anti-HIV-1 activity with EC50 = 41 and 30 microg/mL, respectively.
T2S0605	Liquidambaric lactone	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Liquidambaric lactone 是一种分离自Euonymus grandiflorusWall 中的化合物。
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天然产物

Cat.No: T5783

Synonym: 野蔷薇苷,罗莎白素

Target: Antioxidant, HIV Protease

Cat.No: TN1103

Synonym: 山荷叶素,二叶草素

Target: ATPase, Proton pump, Influenza Virus, HIV Protease

L-Chicoric Acid

Cat.No: T6S2391

Synonym: (-)-Chicoric acid,trans-Caffeoyltartaric acid,Chicoric acid,L-菊苣酸,dicaffeoyltartaric acid,菊苣酸

Target: Others, HIV Protease

Zingibroside R1

Cat.No: T4962

Synonym: Ginsenoside Z-R1,姜状三七皂苷R1,姜状三七苷R1

Target: HIV Protease

1-Deoxymannojirimycin hydrochloride

Cat.No: T22468

Target: Others, Influenza Virus, HIV Protease

Cat.No: T0200

Synonym: Thioctic acid,DL-α-Lipoic acid,(±)-α-Lipoic acid,α-硫辛酸,硫辛酸

Target: Apoptosis, NF-κB, HIV Protease, Mitochondrial Metabolism, Endogenous Metabolite

Cat.No: T4S1383

Synonym: Aescin IA,Escin IA;Aescin IA,Escin IA

Target: HIV Protease

Cat.No: T4S1718

Target: HBV, HIV Protease

Cat.No: T3730

Synonym: NSC 363001,Gallicin,Gallic acid methyl ester,Gallincin,没食子酸甲酯

Target: Reactive Oxygen Species, HIV Protease, Reverse Transcriptase, Antibacterial

Cat.No: T4S1387

Synonym: 七叶皂苷C,异七叶皂苷 IA

Target: HIV Protease

Cat.No: T2S0223

Synonym: 异橙黄酮,6-Demethoxynobiletin

Target: Antioxidant, HIV Protease, Antibacterial, P-gp

Cat.No: TN2283

Target: HIV Protease

1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one

Cat.No: TN5263

Synonym: Xanthohumol,黄腐酚

Target: Apoptosis, BCL, PARP, HCV Protease, IAP, Caspase, HIV Protease, NMDAR, p53

Cat.No: T5782

Synonym: YK FH312,MPC-4326,PA-457,贝韦立马

Target: HIV Protease

1,4-Dicaffeoylquinic acid

Cat.No: T4S1521

Synonym: 1,4-二咖啡酰奎宁酸,洋蓟素

Target: HIV Protease

Cat.No: T3323

Synonym: CCRIS 7123,NSC4060,熊果酮酸,Prunol,3-Ketoursolic acid,Malol,TOS-BB-0966

Target: Apoptosis, HIV Protease, Endogenous Metabolite

Protosappanin A

Cat.No: TJS1779

Synonym: 原苏木素A,PTA

Target: NADPH-oxidase, IL Receptor, IκB/IKK, TNF, NF-κB, TLR, ROS, COX, HIV Protease, JAK, NO Synthase, STAT

4,5-Dicaffeoylquinic acid

Cat.No: T2S1158

Synonym: 3,4-Dicaffeoylquinic acid,异绿原酸C(4,5),Isochlorogenic acid C

Target: Others, HBV, Endogenous Metabolite

Cholic acid sodium

Cat.No: T4537

Synonym: 胆酸钠,[胆酸钠],SodiumCholate

Target: HIV Protease, Endogenous Metabolite

Cat.No: TL0006

Synonym: 菊苣酸,Dicaffeoyltartaric acid,Chicoric Acid

Target: Reactive Oxygen Species, HIV Protease

Cat.No: T6841

Synonym: NSC9168,烟曲霉素,Amebacilin

Target: Others, HIV Protease, Antibiotic, Parasite

Apigenin 7-glucoside

Cat.No: T4S0295

Synonym: 波斯菊,Cosmetin,Cosmosiin,Cosmosioside,Apigenin-7-O-β-D-glucopyranoside,芹甙元-7-葡萄糖苷,Thalictiin,Apigetrin

Target: Reactive Oxygen Species, HIV Protease

Cat.No: T8689

Synonym: CQ,氯喹

Target: SARS-CoV, TLR, HIV Protease, Antibiotic, Parasite, Autophagy

Cat.No: T2930

Synonym: Lipoic acid,Alphalipoic acid,硫辛酸

Target: NF-κB, HIV Protease, Mitochondrial Metabolism, Endogenous Metabolite

Cat.No: T3122

Synonym: Tetrandrine B,防己诺林碱,(+)-Limacine,Hanfangichin B,防己醇灵,(+)-Fangchinoline

Target: Apoptosis, FAK, HIV Protease, Autophagy

Cat.No: TN1622

Synonym: 堪非醇3,4'-二-O-甲醚

Target: NOS, Influenza Virus, COX, HIV Protease, Antibacterial, Antibiotic

Cat.No: T5S2017

Synonym: (-)-Ingenol,巨大戟二萜醇,巨大戟醇

Target: PKC

Ganoderic acid B

Cat.No: TN1059

Target: IL Receptor, HIV Protease, JAK, STAT

Cat.No: TN1727

Synonym: 4,2',4'-三羟基-6'-甲氧基查耳酮,蜡菊亭

Target: Apoptosis, HIV Protease

Cat.No: T4839

Synonym: N-Acetylalanine,N-Acetyl-L-alanine,N-乙酰-L-丙氨酸

Target: Others, Endogenous Metabolite

Cat.No: T5S1103

Synonym: 异莲心碱,Isoliensinin

Target: Apoptosis, Antioxidant

Erythromycin ethylsuccinate

Cat.No: T0474

Synonym: EES,琥乙红霉素

Target: ribosome, HIV Protease, Antibacterial, Antibiotic, Autophagy

Cat.No: T0966

Synonym: 番泻苷A,NSC 112929,番泻苷 A

Target: MAO, HIV Protease

Cat.No: T3321

Synonym: 3-Oxooleanolic acid,3-Oxoolean-12-en-28-oic Acid,Oleanonic Acid,齐墩果酮酸,3-Ketooleanolic Acid

Target: HIV Protease

Cat.No: T16791

Synonym: Mallotoxin,NSC 56346,粗糠柴苦素,NSC 94525

Target: CaMK, Apoptosis, Others, HIV Protease, PKA, PKC, Autophagy

Theaflavin 3,3'-digallate

Cat.No: T5429

Synonym: 茶黄素-3,3'-双没食子酸,8-Gingerol,TFDG

Target: Virus Protease, Antioxidant, HIV Protease, HSV

Cat.No: T2S0731

Synonym: 三叶苷,三叶甙,P-Phlorizin

Target: Amylase

Cat.No: T4S0797

Synonym: 小檗碱,Berberin,Umbellatine,黄连素

Target: Reactive Oxygen Species, Topoisomerase, Endogenous Metabolite, Antibacterial, Antibiotic, Autophagy

Cat.No: T2830

Synonym: 白桦脂酸,桦木酸,ALS-357,Lupatic acid,Betulic acid

Target: Apoptosis, Mitophagy, NF-κB, HIV Protease, Topoisomerase, Endogenous Metabolite, Aminopeptidase, Autophagy

Cat.No: TN5675

Cat.No: TN5012

Target: HIV Protease, Antifection

Methyl salvionolate A

Cat.No: TN4555

Target: HIV Protease

Cat.No: TN6541

Cat.No: T25445

Ganoderic acid GS-2

Cat.No: TN7388

Target: Others

Glycolithocholic acid 3-sulfate

Cat.No: T73758

Target: Others

Pre-schisanartanin B

Cat.No: TN4820

Target: HIV Protease

Cat.No: T75553

Target: Others

Cat.No: TN4835

Target: HIV Protease

Liquidambaric lactone

Cat.No: T2S0605

Target: HIV Protease

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Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02882	HIV-1 (group M, subtype CRF07_BC) gp140 Protein (His) CUB domain containing protein 1	HIV	HEK293 Cells
	HIV-1 (group M, subtype CRF07_BC) gp140 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 78.2 kDa.
TMPY-01373	HIV-1 (group M, subtype CRF07_BC) gp120 Protein (His)	HIV	HEK293 Cells
	HIV-1 (group M, subtype CRF07_BC) gp120 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.8 kDa and the accession number is I6TSC9.
TMPY-01552	HIV-1 (group M, subtype B, strain 92418) p24 Protein (His) Gag-p24	HIV	E. coli
	HIV-1 (group M, subtype B, strain 92418) p24 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 26.5 kDa and the accession number is B6DRA0.
TMPY-04192	HIV-1 (group M, subtype B, strain HXB2) p24 Protein (His) Gag-p24	HIV	E. coli
	HIV-1 (group M, subtype B, strain HXB2) p24 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 26.5 kDa and the accession number is P04591.
TMPJ-01313	HIV-1 gp120 Protein (His) Envelope glycoprotein gp120,Surface protein gp1...	HIV	HEK293 Cells
	Envelope glycoprotein gp160 is single-pass type I membrane protein. The mature envelope protein (Env) consists of a homotrimer of non-covalently associated gp120-gp41 heterodimers. It is cleaved into the following 2 chains: glycoprotein 120 and transmembrane protein gp41. The resulting complex protrudes from the virus surface as a spike. The 17 amino acids long immunosuppressive region is present in many retroviral envelope proteins. Synthetic peptides derived from this relatively conserved sequ...
TMPY-00426	HIV-1 (group P, strain RBF168) gp140 Protein (hFc) CUB domain containing protein 1	HIV	HEK293 Cells
	HIV-1 (group P, strain RBF168) gp140 Protein (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 99.4 kDa and the accession number is D0VTQ8.
TMPY-04198	HIV-1 (group O, strain BCF06) p24 Protein (His) Gag-p24	HIV	E. coli
	HIV-1 (group O, strain BCF06) p24 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 26.6 kDa and the accession number is C7G2S7.
TMPY-00427	HIV-1 (group P, strain RBF168) gp120 Protein (His)	HIV	HEK293 Cells
	HIV-1 (group P, strain RBF168) gp120 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.2 kDa and the accession number is D0VTQ8.
TMPY-01408	HIV-1 (group M, subtype CRF07_BC) gp140 Protein (hFc) CUB domain containing protein 1	HIV	HEK293 Cells
	HIV-1 (group M, subtype CRF07_BC) gp140 Protein (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 98 kDa.
TMPY-06486	HIV-1 (group M, subtype CRF07_BC) gp120 Protein (His), Biotinylated	HIV	HEK293 Cells
	HIV-1 (group M, subtype CRF07_BC) gp120 Protein (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.8 kDa and the accession number is AFM77980.1.
TMPY-01556	HIV-1 (group N, strain 06CM-U14296) p24 protein (His) Gag-p24	HIV	E. coli
	HIV-1 (group N, strain 06CM-U14296) p24 protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 27 kDa.
TMPY-04196	HIV-1 (group M, subtype D, strain NDK) p24 Protein (His) Gag-p24	HIV	E. coli
	HIV-1 (group M, subtype D, strain NDK) p24 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 26.6 kDa and the accession number is P18800.
TMPY-04915	HIV-1 (group M, subtype B, Isolate MN) gp120 Protein (His)	HIV	HEK293 Cells
	HIV-1 (group M, subtype B, Isolate MN) gp120 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55.8 kDa and the accession number is Q9YUL5.
TMPY-00316	HIV-1 (group M, subtype B, isolate BAL) gp120 Protein (His)	HIV	HEK293 Cells
	HIV-1 (group M, subtype B, isolate BAL) gp120 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55.4 kDa and the accession number is Q03805.
TMPY-00425	HIV-1 (group M, subtype A, strain 92UG037.1) gp140 Protein (hFc) CUB domain containing protein 1	HIV	HEK293 Cells
	HIV-1 (group M, subtype A, strain 92UG037.1) gp140 Protein (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 97.4 kDa and the accession number is P90249.
TMPY-04871	HIV-1 (group M, subtype C, strain 92BR025) gp140 Protein (Fc) CUB domain containing protein 1	HIV	HEK293 Cells
	HIV-1 (group M, subtype C, strain 92BR025) gp140 Protein (Fc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 99.9 kDa and the accession number is O12164.
TMPY-04194	HIV-1 (group M, subtype C, strain 92BR025) p24 Protein (His) Gag-p24	HIV	E. coli
	HIV-1 (group M, subtype C, strain 92BR025) p24 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 26.5 kDa and the accession number is O12157.
TMPY-01558	HIV-1 (group N, strain 06CM-U14296) gp160 (gp120 subunit) Protein (His)	HIV	HEK293 Cells
	HIV-1 (group N, strain 06CM-U14296) gp160 (gp120 subunit) Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.4 kDa.
TMPH-01519	HIV-1 (group M, subtype C, isolate 92BR025) Protein Vpr (His & Myc) Viral protein R,vpr,Protein Vpr,R ORF protein	HIV-1	E. coli
	HIV-1 (group M, subtype C, isolate 92BR025) Protein Vpr (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.9 kDa and the accession number is O12160.
TMPY-00309	HIV-1 (group M, subtype B, strain SHIV-89.6P) gp120 Protein (His)	HIV	HEK293 Cells
	HIV-1 (group M, subtype B, strain SHIV-89.6P) gp120 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55.4 kDa and the accession number is O11407.
TMPH-01520	HIV-1 (group M, subtype K, isolate 96CM-MP535) Protein Vpr (His & Myc) vpr,R ORF protein,Protein Vpr,Viral protein R	HIV-1	E. coli
	HIV-1 (group M, subtype K, isolate 96CM-MP535) Protein Vpr (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.8 kDa and the accession number is P0C1P2.
TMPY-00302	HIV-1 (group M, subtype A, isolate 92RW020) gp160 (gp120 subunit) Protein (His)	HIV	HEK293 Cells
	HIV-1 (group M, subtype A, isolate 92RW020) gp160 (gp120 subunit) Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52.2 kDa and the accession number is Q6BC58.
TMPY-01442	DMBT1 Protein, Human, Recombinant (His) GP340,deleted in malignant brain tumors 1,muclin	Human	HEK293 Cells
	Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB domains, 14SRCR domains and 1ZP domain. It is highly expressed in alveolar and macrophage tissues. In some macrophages, expression is detected on the membrane, and in other macrophages, it is strongly expressed in the phagosome/phagolysosome compartments. Defects in DMBT1 are invo...
TMPK-00897	CCR8 Protein, Human, Recombinant (mFc) GPR-CY6,CY6,CKRL1,CMKBRL2,TER-1,CDw1	Human	HEK293 Cells
	CC chemokine receptor (CCR) 8 (previously called CKR-L1 or TER1 and designated CD198), which is expressed on Th2 cells and eosinophils, has been implicated in allergic diseases. CCR8 may regulate monocyte chemotaxis and thymic cell line apoptosis and is alternative coreceptor with CD4 for HIV-1 infection. CCR8 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 30.25 kDa and the accession number is P51685-1.
TMPK-00896	CCR8 Protein, Human, Recombinant (hFc) GPR-CY6,CKR-L1,CMKBRL2,ChemR1,CDw1	Human	HEK293 Cells
	CC chemokine receptor (CCR) 8 (previously called CKR-L1 or TER1 and designated CD198), which is expressed on Th2 cells and eosinophils, has been implicated in allergic diseases. CCR8 may regulate monocyte chemotaxis and thymic cell line apoptosis and is alternative coreceptor with CD4 for HIV-1 infection. CCR8 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 30.62 kDa and the accession number is P51685-1.
TMPJ-00873	CCL3L1 Protein, Human, Recombinant (His) CCL3L3,G0S19-2,CCL3L1,Tonsillar Lymphocyte...	Human	HEK293 Cells
	C-C Motif Chemokine 3-Like 1 (CCL3L1) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. CCL3L1 is a ligand for CCR1, CCR3 and CCR5. CCL3L1 binds to several chemokine receptors including chemokine binding protein 2 and chemokine (C-C motif) receptor 5 (CCR5). CCR5 is a co-receptor for HIV, and binding of this protein to CCR5 inhibits HIV entry. The processed form LD78-beta (3-70) shows a 20-fold to 30-fold higher chemotactic activity and is a very potent inhibitor o...
TMPH-01248	ADAR Protein, Human, Recombinant (His & SUMO) ADAR1,IFI-4,136 kDa double-stranded RNA-bi...	Human	E. coli
	Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translation by changing codons and hence the amino acid sequence of proteins; pre-mRNA splicing by altering splice site recognition sequences; RNA stability by changing sequences involved in nuclease recognition; genetic stability in the case of RNA virus genomes by changing sequences duri...
TMPH-02300	RAD23A Protein, Human, Recombinant (His) UV excision repair protein RAD23 homolog A,RAD23A	Human	E. coli
	Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to 'Lys-48'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to 'Lys-63'-linked polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome.; Involved in nucleotide excision repair and is thought to be functional equivalent for RAD23B in global genome nucle...
TMPK-01316	CCR8 Protein, Cynomolgus, Recombinant (mFc) GPR-CY6,CY6,CKRL1,CDw198,CMKBR8,ChemR1...	Cynomolgus	HEK293 Cells
	CC chemokine receptor (CCR) 8 (previously called CKR-L1 or TER1 and designated CD198), which is expressed on Th2 cells and eosinophils, has been implicated in allergic diseases. CCR8 may regulate monocyte chemotaxis and thymic cell line apoptosis and is alternative coreceptor with CD4 for HIV-1 infection. CCR8 Protein, Cynomolgus, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 29.73 kDa and the accession number is A0A8J8XUI3.
TMPY-03413	PPIL2 Protein, Human, Recombinant (aa 280-457, His) UBOX7,Cyp-60,CYP60,CYC4,peptidylprolyl isomerase (cyclophili...	Human	E. coli
	PPIL2, is an enzyme that belongs to the cyclophilin family. The cyclophilins are peptidylprolyl isomerases and are highly conserved ubiquitous. They play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. PPIL2 interacts with the proteinase inhibitor eglin c and is localized in the nucleus. It contains 1 PPIL2 cyclophilin-type domain and 1 U-box domain. PPIL2 accelerate the folding of proteins. It catalyzes the cis-trans isomerization of pro...
TMPJ-01330	CD299 Protein, Human, Recombinant (His & Flag) DC-SIGNR,L-SIGN,CD299,CD209L,LSIGN,C-type lectin domain fami...	Human	HEK293 Cells
	CD299 is also known as DC-SIGNR and CLEC4M, is a type II integral membrane protein. DC-SIGNR exists as a homotetramer, and the tandem repeat domain, also called neck domain, mediates oligermerization. Multiple human DC-SIGN/CD209 splice forms exist, generating both membrane-bound and soluble forms. DC-SIGNR is ragarded as a pathogen-recognition receptor involved in peripheral immune surveillance in liver, and probably mediate the endocytosis of pathogens which are subsequently degraded in lysoso...
TMPH-01064	CCR4 Protein, Human, Recombinant (His & SUMO) CMKBR4,CD194,K5-5,CCR-4,C-C chemokine receptor type...	Human	E. coli
	High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival. CCR4 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expressio...
TMPJ-01037	CXCR4 Protein, Human, Recombinant (hFc) CXCR4,CD184,Fusin,D2S201E,FB22,HM89,HSY3RR...	Human	HEK293 Cells
	C-X-C chemokine receptor type 4 (CXCR4) is an alpha-chemokine receptor specific for stromal-derived-factor-1 (SDF-1 also called CXCL12), a molecule endowed with potent chemotactic activity for lymphocytes. This receptor is one of several chemokine receptors that HIV isolates can use to infect CD4+ T cells. CXCR4 stands out for its pleiotropic roles in both physiological and pathological conditions and it represents a crucial target in drug development. CXCL12 is the principal CXCR4 specific liga...
TMPY-03285	PPIL1 Protein, Human, Recombinant (His) CGI-124,PPIase,CYPL1,hCyPX,peptidylprolyl ...	Human	E. coli
	PPIL1 is a member of the cyclophilin family. Cyclophilins are well conserved and ubiquitous. Members of cyclophilin family take a significant part in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. PPIL1 is a peptidylprolyl isomerase(PPIase). It increases the folding of proteins and catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIL1 is involved in proliferation of cancer cells through modulation of phosphorylation of...
TMPH-01065	CCR4 Protein-VLP, Human, Recombinant (His) CC-CKR-4,CCR4,CCR-4,CD194,C-C chemokine receptor ty...	Human	HEK293 Cells
	High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival. CCR4 Protein-VLP, Human, Recombinant (His) is expressed in HEK293 mammalian cel...
TMPJ-00679	SGTA Protein, Human, Recombinant (His) α-SGT,Alpha-SGT,SGT,Small Glutamine-Rich Tetratricopeptide R...	Human	E. coli
	Small Glutamine-Rich Tetratricopeptide Repeat-Containing Protein α (SGTA) is an ubiquitously expressed protein which belongs to the SGT Family. SGTA contains three TPR Protein-Protein Interaction Duplicates. SGTA is a co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity. SGTA is capable of interacting with the major nonstructural protein of Parvovirus H-1 and 70-kDa heat shock cognate protein. It interacts with NS1 from Parvovirus H-1, with Vpu and Gag from HIV...
TMPK-00668	IL-21R Protein, Cynomolgus, Recombinant (aa 41-254, His) NILR,IL-21 receptor,IL-21R,CD360	Cynomolgus	HEK293 Cells
	IL-21 and IL-21R were highly expressed in the lesional skin and peripheral blood of psoriasis patients. IL-21 promoted CD4 T cells proliferation and Th17 cells differentiation and inhibiting Treg cells differentiation by upregulating RORγt expression and downregulating Foxp3 expression, with increased expression and secretion of IL-17A and IL-22.Microbial translocation and the associated immune activation during HIV-1 infection may lead to high expression levels of the IL-21R activation marker i...
TMPJ-00810	ITGA5 Protein, Human, Recombinant (His) FNRA,Integrin α-5,Integrin Alpha-F,Fibronectin Receptor Subu...	Human	HEK293 Cells
	Integrin α-5 belongs to the Integrin α chain family and contains 7 FG-GAP repeats. Integrin α-5 joins with Integrin-β1 to form a fibronectin and laminin receptor which recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. It is expressed on fibroblasts, endothelial cells, peripheral T cells and platelets. Integrin α-5 undergoes post-translational cleavage in the ext...
TMPH-02212	TLR8 Protein, Human, Recombinant (His) TLR8,Toll-like receptor 8	Human	P. pastoris (Yeast)
	Endosomal receptor that plays a key role in innate and adaptive immunity. Controls host immune response against pathogens through recognition of RNA degradation products specific to microorganisms that are initially processed by RNASET2. Recognizes GU-rich single-stranded RNA (GU-rich RNA) derived from SARS-CoV-2, SARS-CoV-1 and HIV-1 viruses. Upon binding to agonists, undergoes dimerization that brings TIR domains from the two molecules into direct contact, leading to the recruitment of TIR-con...
TMPJ-00394	LDLR Protein, Human, Recombinant (Avi & His), Biotinylated Low-Density Lipoprotein Receptor,LDL Receptor,LDLR	Human	HEK293 Cells
	Low-density lipoprotein receptor 9 (LDL receptor) is a single-pass type I membrane protein which belongs to the LDLR family. It contains 3 EGF-like domains, 7 LDL-receptor class A domains, and 6 LDL-receptor class B repeats. This protein binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. In case of HIV-1 infection, it functions as a r...
TMPJ-01122	KARS Protein, Human, Recombinant (His) Lysine--tRNA Ligase,Lysyl-tRNA Synthetase,LysRS,KARS,KIAA007...	Human	HEK293 Cells
	Lysine-tRNA ligase, also known as Lysyl-tRNA synthetase, LysRS, KARS and KIAA0070, belongs to the class-II aminoacyl-tRNA synthetase family. The N-terminal cytoplasmic domain (1-65) is a functional tRNA-binding domain, which is required for nuclear localization, is involved in the interaction with DARS, but has a repulsive role in the binding to EEF1A1. A central domain (208-259) is involved in homodimerization and is required for interaction with HIV-1 GAG and incorporation into virions. KARS c...
TMPY-00493	IL-19 Protein, Human, Recombinant (His) interleukin 19,Interleukin-19,IL-1	Human	Baculovirus Insect Cells
	The molecular features at the IL19 locus may modestly alter the establishment of HIV-1 infection. Interleukin (IL) 19, IL-20, and IL-24 belong to the IL-10 cytokine family and have been identified to play a role in the regulation of epidermal functions and inflammation. The expression of IL19 in biopsies of patients with active ulcerative colitis was increased compared with patients with quiescent ulcerative colitis and that colitis was attenuated in IL-19-deficient mice. The disruption of the e...
TMPY-01711	Serpin B2 Protein, Human, Recombinant (GST) PAI,serpin peptidase inhibitor, clade B (ovalbumin), member ...	Human	Baculovirus Insect Cells
	Serpins are the largest and most diverse family of serine protease inhibitors which are involved in some fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner.SerpinB2, also known as Plasminogen activator inhibitor 2, Placental plasminogen activator inhibitor, Monocyte Arg-serpin, Urokinase inhibitor and PAI2, is a cytoplasm protein that belongs to the serpin fa...
TMPJ-00831	CCL3 Protein, Mouse, Recombinant (His) LD78 α,MIP-1 α,MIP1-a,MIP-1 alpha...	Mouse	E. coli
	C-C Motif Chemokine 3 (MIP-1 alpha,CCL3 ) is a member of the beta or CC subfamily of chemokines and is closely related to CCL4/MIP-1 beta. CCL3 expression can be induced in a variety of hematopoietic cells, fibroblasts, smooth muscle cells, and epithelial cells. Mature mouse CCL3 shares 73%, 91%, and 82% amino acid sequence identity with human, rat, and cotton rat CCL3, respectively. CCL3 exerts its biological functions through interactions with CCR1, CCR3, and CCR5. It is cleared from the extra...
TMPY-04451	AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) AMPK, AMPK(α1, β1, γ1)	Human	Baculovirus Insect Cells
	AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&Q13131-1.
TMPY-00886	MMP-1 Protein, Human, Recombinant (His) CLGN,CLG,matrix metallopeptidase 1	Human	HEK293 Cells
	MMP1, also known as MMP-1, contains 4 hemopexin-like domains and is a member of the matrix metalloproteinase (MMP) family. Matrix metalloproteases, also called matrixins, are zinc-dependent endopeptidases that are the major proteases involved in ECM degradation. MMPs are capable of degrading a wide range of extracellular molecules and some bioactive molecules. MMP activity is regulated by two major endogenous inhibitors: alpha2-macroglobulin and tissue inhibitors of metalloproteases (TIMPs). MMP...
TMPY-03878	Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) Integrin alpha V β6,ITGAV & ITGB6,integrin, alpha 5 (fibrone...	Human	HEK293 Cells
	Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1.
TMPY-02501	CD3D & CD3E Heterodimer Protein, Human, Recombinant CD3d molecule, δ (CD3-TCR complex),CD3-δ,CD3d molecule, delt...	Human	HEK293 Cells
	CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1.
TMPY-02030	CD82 Protein, Human, Recombinant (His) CD82 molecule,SAR2,R2,KAI-1,4F9,KAI1,C33,T...	Human	HEK293 Cells
	CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signalling. Downregulation of CD82 expression is associated with the advanced stages of many human cancers and correlates with the acquisition of metastatic potential. Recent stud...
TMPY-01894	SIGIRR Protein, Human, Recombinant (His) TIR8,single immunoglobulin and toll-interleukin 1 r...	Human	HEK293 Cells
	SIGIRR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14 kDa and the accession number is Q6IA17-1.
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重组蛋白

HIV-1 (group M, subtype CRF07_BC) gp140 Protein (His)

Cat.No: TMPY-02882

Species: HIV

Expression System: HEK293 Cells

HIV-1 (group M, subtype CRF07_BC) gp120 Protein (His)

Cat.No: TMPY-01373

Species: HIV

Expression System: HEK293 Cells

HIV-1 (group M, subtype B, strain 92418) p24 Protein (His)

Cat.No: TMPY-01552

Species: HIV

Expression System: E. coli

HIV-1 (group M, subtype B, strain HXB2) p24 Protein (His)

Cat.No: TMPY-04192

Species: HIV

Expression System: E. coli

HIV-1 gp120 Protein (His)

Cat.No: TMPJ-01313

Species: HIV

Expression System: HEK293 Cells

HIV-1 (group P, strain RBF168) gp140 Protein (hFc)

Cat.No: TMPY-00426

Species: HIV

Expression System: HEK293 Cells

HIV-1 (group O, strain BCF06) p24 Protein (His)

Cat.No: TMPY-04198

Species: HIV

Expression System: E. coli

HIV-1 (group P, strain RBF168) gp120 Protein (His)

Cat.No: TMPY-00427

Species: HIV

Expression System: HEK293 Cells

HIV-1 (group M, subtype CRF07_BC) gp140 Protein (hFc)

Cat.No: TMPY-01408

Species: HIV

Expression System: HEK293 Cells

HIV-1 (group M, subtype CRF07_BC) gp120 Protein (His), Biotinylated

Cat.No: TMPY-06486

Species: HIV

Expression System: HEK293 Cells

HIV-1 (group N, strain 06CM-U14296) p24 protein (His)

Cat.No: TMPY-01556

Species: HIV

Expression System: E. coli

HIV-1 (group M, subtype D, strain NDK) p24 Protein (His)

Cat.No: TMPY-04196

Species: HIV

Expression System: E. coli

HIV-1 (group M, subtype B, Isolate MN) gp120 Protein (His)

Cat.No: TMPY-04915

Species: HIV

Expression System: HEK293 Cells

HIV-1 (group M, subtype B, isolate BAL) gp120 Protein (His)

Cat.No: TMPY-00316

Species: HIV

Expression System: HEK293 Cells

HIV-1 (group M, subtype A, strain 92UG037.1) gp140 Protein (hFc)

Cat.No: TMPY-00425

Species: HIV

Expression System: HEK293 Cells

HIV-1 (group M, subtype C, strain 92BR025) gp140 Protein (Fc)

Cat.No: TMPY-04871

Species: HIV

Expression System: HEK293 Cells

HIV-1 (group M, subtype C, strain 92BR025) p24 Protein (His)

Cat.No: TMPY-04194

Species: HIV

Expression System: E. coli

HIV-1 (group N, strain 06CM-U14296) gp160 (gp120 subunit) Protein (His)

Cat.No: TMPY-01558

Species: HIV

Expression System: HEK293 Cells

HIV-1 (group M, subtype C, isolate 92BR025) Protein Vpr (His & Myc)

Cat.No: TMPH-01519

Species: HIV-1

Expression System: E. coli

HIV-1 (group M, subtype B, strain SHIV-89.6P) gp120 Protein (His)

Cat.No: TMPY-00309

Species: HIV

Expression System: HEK293 Cells

HIV-1 (group M, subtype K, isolate 96CM-MP535) Protein Vpr (His & Myc)

Cat.No: TMPH-01520

Species: HIV-1

Expression System: E. coli

HIV-1 (group M, subtype A, isolate 92RW020) gp160 (gp120 subunit) Protein (His)

Cat.No: TMPY-00302

Species: HIV

Expression System: HEK293 Cells

DMBT1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01442

Species: Human

Expression System: HEK293 Cells

CCR8 Protein, Human, Recombinant (mFc)

Cat.No: TMPK-00897

Species: Human

Expression System: HEK293 Cells

CCR8 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00896

Species: Human

Expression System: HEK293 Cells

CCL3L1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00873

Species: Human

Expression System: HEK293 Cells

ADAR Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01248

Species: Human

Expression System: E. coli

RAD23A Protein, Human, Recombinant (His)

Cat.No: TMPH-02300

Species: Human

Expression System: E. coli

CCR8 Protein, Cynomolgus, Recombinant (mFc)

Cat.No: TMPK-01316

Species: Cynomolgus

Expression System: HEK293 Cells

PPIL2 Protein, Human, Recombinant (aa 280-457, His)

Cat.No: TMPY-03413

Species: Human

Expression System: E. coli

CD299 Protein, Human, Recombinant (His & Flag)

Cat.No: TMPJ-01330

Species: Human

Expression System: HEK293 Cells

CCR4 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01064

Species: Human

Expression System: E. coli

CXCR4 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-01037

Species: Human

Expression System: HEK293 Cells

PPIL1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03285

Species: Human

Expression System: E. coli

CCR4 Protein-VLP, Human, Recombinant (His)

Cat.No: TMPH-01065

Species: Human

Expression System: HEK293 Cells

SGTA Protein, Human, Recombinant (His)

Cat.No: TMPJ-00679

Species: Human

Expression System: E. coli

IL-21R Protein, Cynomolgus, Recombinant (aa 41-254, His)

Cat.No: TMPK-00668

Species: Cynomolgus

Expression System: HEK293 Cells

ITGA5 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00810

Species: Human

Expression System: HEK293 Cells

TLR8 Protein, Human, Recombinant (His)

Cat.No: TMPH-02212

Species: Human

Expression System: P. pastoris (Yeast)

LDLR Protein, Human, Recombinant (Avi & His), Biotinylated

Cat.No: TMPJ-00394

Species: Human

Expression System: HEK293 Cells

KARS Protein, Human, Recombinant (His)

Cat.No: TMPJ-01122

Species: Human

Expression System: HEK293 Cells

IL-19 Protein, Human, Recombinant (His)

Cat.No: TMPY-00493

Species: Human

Expression System: Baculovirus Insect Cells

Serpin B2 Protein, Human, Recombinant (GST)

Cat.No: TMPY-01711

Species: Human

Expression System: Baculovirus Insect Cells

CCL3 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00831

Species: Mouse

Expression System: E. coli

AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04451

Species: Human

Expression System: Baculovirus Insect Cells

MMP-1 Protein, Human, Recombinant (His)

Cat.No: TMPY-00886

Species: Human

Expression System: HEK293 Cells

Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)

Cat.No: TMPY-03878

Species: Human

Expression System: HEK293 Cells

CD3D & CD3E Heterodimer Protein, Human, Recombinant

Cat.No: TMPY-02501

Species: Human

Expression System: HEK293 Cells

CD82 Protein, Human, Recombinant (His)

Cat.No: TMPY-02030

Species: Human

Expression System: HEK293 Cells

SIGIRR Protein, Human, Recombinant (His)

Cat.No: TMPY-01894

Species: Human

Expression System: HEK293 Cells

--------- 更多 ---------

Cat. No.	Product Name	Target	Signaling Pathways
TMIJ-0076	Ritonavir-13C-d3
	Ritonavir-13C-d3 是 Ritonavir 的 13C 和氘代化合物。Ritonavir 的 CAS 号为 155213-67-5。Ritonavir 是一种 HIV 蛋白酶抑制剂，可研究 HIV 感染和 AIDS 。它也是SARS-CoV 3CLpro的抑制剂，IC50为 1.61 μM。
T11814	Lamivudine 13C,15N2	Others	Others
	Lamivudine 13C,15N2, an impurity of Lamivudine (BCH-189), functions as an inhibitor of both HIV-1/2 reverse transcriptase and hepatitis B virus reverse transcriptase, classifying it as a nucleoside reverse transcriptase inhibitor (NRTIs).
TMID-0082	Lopinavir-d8
	Lopinavir-d8 是 Lopinavir 的氘代化合物。Lopinavir 的 CAS 号为 192725-17-0。Lopinavir 是一种选择性肽模拟 HIV-1 蛋白酶的高效抑制剂。它通过阻止 HIV-1 的成熟而起作用，从而阻断其感染性。它也是SARS-CoV 3CLpro的抑制剂。
TMID-0266	Stavudine-α,α,α,6-d4
	Stavudine-α,α,α,6-d4 是 Stavudine 的氘代化合物。Stavudine 的 CAS 号为 3056-17-5。Stavudine 是一种口服活性核苷逆转录酶抑制剂，还抑制线粒体 DNA 的复制，具有抗HIV-1和HIV-2的活性。它降低 NLRP3 炎症小体激活，调节淀粉样 β 自噬，诱导细胞凋亡。
TMID-0206	Nevirapine-d3
	Nevirapine-d3 是 Nevirapine 的氘代化合物。Nevirapine 的 CAS 号为 129618-40-2。Nevirapine 是一种HIV-1逆转录酶非核苷抑制剂，Ki值为 270 μM，可用于研究 HIV/AIDS。
TMID-0205	Nevirapine-d4
	Nevirapine-d4 是 Nevirapine 的氘代化合物。Nevirapine 的 CAS 号为 129618-40-2。Nevirapine 是一种HIV-1逆转录酶非核苷抑制剂，Ki值为 270 μM，可用于研究 HIV/AIDS。
TMID-0285	Lamivudine-13C-d2
	Lamivudine-13C-d2 是 Lamivudine 的 13C 和氘代化合物。Lamivudine 的 CAS 号为 134678-17-4。Lamivudine 是一种核苷逆转录酶抑制剂，可抑制HIV逆转录酶1和2 以及乙型肝炎病毒的逆转录酶。
TMIJ-0109	Erythromycin Ethylsuccinate-13C-d3
	Erythromycin Ethylsuccinate-13C-d3 是 Erythromycin Ethylsuccinate 的 13C 和氘代化合物。Erythromycin Ethylsuccinate 的 CAS 号为 1264-62-6。Erythromycin Ethylsuccinate是一种由红链霉菌产生的大环内酯类抗生素，有潜力用于多种细菌感染。它具有抗HIV-1病毒活性。

同位素标记化合物

Ritonavir-13C-d3

Cat.No: TMIJ-0076

Lamivudine 13C,15N2

Cat.No: T11814

Target: Others

Cat.No: TMID-0082

Stavudine-α,α,α,6-d4

Cat.No: TMID-0266

Cat.No: TMID-0206

Cat.No: TMID-0205

Lamivudine-13C-d2

Cat.No: TMID-0285

Erythromycin Ethylsuccinate-13C-d3

Cat.No: TMIJ-0109

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