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Targets Recommended: HIV Protease HIV Protease

760

抑制剂 & 化合物

159

天然产物

7

化合物库

59

重组蛋白

14

同位素标记化合物

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Cat. No. Product Name
L1720 核苷类化合物库

334 compounds
334 种核苷类化合物,包括核苷酸、核苷酸类似物及衍生物等,适用于抗病毒、抗肿瘤、抗真菌、抗抑郁等药物的研发;
L1700 抗病毒库

1040 compounds
1040 种具有抗病毒活性的化合物的特有集合,是筛选新型抗病毒药的有效工具;可用于高通量筛选和高内涵筛选;
L1800 抗感染化合物库

2938 compounds
2938 种具有抗感染活性的化合物的特有集合,包括抗细菌、抗真菌、抗巨细胞病毒、抗HIV、抗SARS、抗流感等活性;
L9420 外泌体相关化合物库

76 compounds
76 种外泌体相关的化合物,可以用于高通量和高内涵筛选;
L9400 PPI抑制剂库

485 compounds
485 种已知活性的 PPI 相关的抑制剂,可用于高通量、高内涵筛选;
L1100 蛋白酶抑制剂库

343 compounds
343 种已知的小分子蛋白酶抑制剂的特有集合,可用于高通量筛选和高内涵筛选;
L7600 趋化因子抑制剂库

59 compounds
59 种趋化因子或其受体抑制剂的独特集合,可用于高通量筛选和高内涵筛选;

化合物库

核苷类化合物库
Cat.No: L1720
Compounds: 334
抗病毒库
Cat.No: L1700
Compounds: 1040
抗感染化合物库
Cat.No: L1800
Compounds: 2938
外泌体相关化合物库
Cat.No: L9420
Compounds: 76
PPI抑制剂库
Cat.No: L9400
Compounds: 485
蛋白酶抑制剂库
Cat.No: L1100
Compounds: 343
趋化因子抑制剂库
Cat.No: L7600
Compounds: 59
Cat. No. Product Name Target Signaling Pathways
T24141 HIV-1 Inhibitor 18A

HIV-1 Inhibitor-18A

HIV Protease Microbiology/Virology; Proteases/Proteasome
HIV-1 Inhibitor 18A (HIV-1 Inhibitor-18A) 特异性抑制多种 HIV-1 分离株的进入。
TP1149 HIV-1 Rev (34-50)

HIV-1 Rev 34-50,HIV-1 rev Protein (34-50)

HIV Protease Microbiology/Virology; Proteases/Proteasome
HIV-1 Rev (34-50) (HIV-1 rev Protein (34-50)) 是一种具有抗 HIV-1 活性的 17 个氨基酸多肽。 HIV-1 Rev (34-50) 源自 HIV-1 中 Rev 的 Rev 响应元件结合域。
T67833 HIV-1 inhibitor-54

HIV Protease Microbiology/Virology; Proteases/Proteasome
HIV-1 inhibitor-54 是一种有效的 HIV-1 抑制剂,在 MT-4 细胞中对 WT HIV-1 (菌株 IIIB) x 显示出抗 HIV 活性(EC50 : 32 nM)。HIV-1 inhibitor-54 可用于研究病毒感染。
T9039 HIV-1 Nef-IN-1

HIV Protease Microbiology/Virology; Proteases/Proteasome
HIV-1 Nef-IN-1 是 HIV-1 Nef 蛋白的抑制剂。 它有效地竞争 Nef-SH3Hck 相互作用,Kd 值为 6.7 μM。
T9854 HIV-1 inhibitor-6 

3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-

HIV Protease Microbiology/Virology; Proteases/Proteasome
HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) 是一种有效的HIV-1 pre-mRNA 选择性剪接抑制剂,可以阻断HIV 复制。
T61793 HIV-IN-6

HIV Protease Microbiology/Virology; Proteases/Proteasome
HIV-IN-6 是一种 HIV 病毒抑制剂,可抑制HIV 病毒的复制。HIV-IN-6 具有抗HIV 病毒的活性,通过靶向与病毒 Nef 蛋白相互作用的 Src 家族激酶 (SFK) (如 Hck) 而起作用。
TP1637 HIV gag peptide (197-205)

HIV gag peptide 197-205

HIV gag peptide (197-205) is a H-2Kd-restricted epitope derived from the p24 portion of the HIV-1 gag protein and composed of the amino acid 197-205 (AMQMLKETI).
TP1674 HIV p17 Gag (77-85)

HIV p17 Gag 77-85

HIV p17 Gag (77-85) is an attractive target for molecular intervention, because it is involved in the viral replication cycle at both the pre- and postintegration levels. In the present experiments, we targeted p17 by intracellularly expressing a cDNA enc
T40719 (Cys47)-HIV-1 tat Protein (47-57)

(Cys47)-HIV-1 tat Protein (47-57)

(Cys47)-HIV-1 tat Protein (47-57) possesses membrane translocation functionality and can serve as a surface derivatization agent for magnetic pharmaceuticals, thereby enhancing their uptake into specific target cells.
T60742 HIV-1 integrase inhibitor 8

HIV Protease Microbiology/Virology; Proteases/Proteasome
HIV-1 integrase inhibitor 8 是一种 HIV-1 整合酶抑制剂,整合是HIV 复制的必要步骤。
T39729 HIV Protease Substrate 1

HIV Protease Substrate 1 is a fluorogenic compound that offers insights into the enzymatic activity of HIV protease, making it a valuable tool for studying this aspect.
TP1743 MPG, HIV related

MPG, a 27-amino acid peptide compound, is derived from the fusion peptide domain of HIV-1 gp41 and the nuclear localisation sequence of SV40 large T antigen. As a potent delivery agent, MPG enables efficient and widespread transport of nucleic acids and oligonucleotides into cultured cells.
T11564 HIV-1 inhibitor-3

Others Others
HIV-1 inhibitor-3 is an HIV infection inhibitor.
T11566 HIV-1 integrase inhibitor

Others Others
Hiv-1 integrase inhibitor is an effective anti-HIV drug.
T11565 HIV-1 integrase inhibitor 7

Others Others
HIV-1 integrase inhibitor 7 is a potent HIV-1 integrase inhibitor (IC50: 33.3 nM).
T11568 HIV-1 integrase inhibitor 4

Others Others
HIV-1 integrase inhibitor 4 is an HIV-1 integrase strand transfer (INST) inhibitor (IC50: 3.7 nM).
TP1776 HIV-1 TAT 48-60

HIV-1 TAT (48-60) is a cell-penetrating peptide derived from the human immunodeficient virus (HIV)-1 Tat protein residue 48-60. This is one of the cell-penetrating peptides generated from the human immunodeficient virus -1 Tat protein residue 48-60.
T27030 CK176

HIV-1 inhibitor-34,HIV-1 inhibitor 34,CK 176,CK-176,HIV-1 inhibitor34

Others Others
CK176 is a capsid targeted inhibitor of HIV-1 replication. CK176 shows an 11-fold improvement over I-XW-053 in blocking HIV-1 replication in primary human peripheral blood mononuclear cells (PBMCs).
T11567 HIV-1 integrase inhibitor 3

Others Others
HIV-1 integrase inhibitor 3 is an HIV-1 integrase strand transfer (INST) inhibitor (IC50: 2.7 nM).
T76502 HIV-1, HIV-2 Protease Substrate

HIV-1,HIV-2Protease Substrate 是HIV-1,HIV-2蛋白酶的底物。HIV-1和HIV-2蛋白酶底物结合残基有 4 个保守取代残基。
T15483 LEDGIN6

HIV-1 integrase inhibitor 2

Others Others
HIV-1 integrase inhibitor 2 is used for the treatment of human immunodeficiency virus (HIV) infection.
T1883 Des(benzylpyridyl) Atazanavi

HIV Protease Microbiology/Virology; Proteases/Proteasome
Des(benzylpyridyl) Atazanavi 是 Atazanavir 的 N-脱烷基代谢物 (M1),一种 HIV 蛋白酶抑制剂。
TP1809 TAT

HIV Protease Microbiology/Virology; Proteases/Proteasome
TAT 源自人免疫缺陷病毒的转录反式激活因子,是一种细胞穿透肽。它可以增加异源蛋白质的产量和溶解度。
TP1185 Cys-TAT(47-57)

Cys-[HIV-Tat (47-57)]

Cys-TAT(47-57) (Cys-[HIV-Tat (47-57)]) is an arginine rich cell penetrating peptide derived from the HIV-1 transactivating protein.This peptide corresponds to the protein transduction domain of the TAT protein.
T74282 HIV-IN-2

Others Others
HIV-IN-2 (Compound 100) 是一种有效的HIV 抑制剂。HIV-IN-2 具有研究HIV 感染的潜力。
T79974 HIV-IN-8

Others Others
HIV-IN-8(Compound 9)为抗HIV药物,通过抑制HIV复制发挥作用,其半抑制浓度(EC50)为13 μg/mL。
T77792 HIV Peptide T

Others Others
HIV Peptide T(Peptide T),这种合成的八肽是HIV感染治疗中的一种抗病毒药物,其主要通过竞争性抑制gp120(HIV表面蛋白)与CD4受体的相互作用,同时与血管肠肽(vasointestinal peptide, VIP)受体同源结合并且阻断细胞因子的产生与作用来发挥功效。
T60426 HIV-IN-4

Others Others
HIV-IN-4 (Compound 12) 是有效的HIV 抑制剂,具有良好的抗 HIV 病毒活性。
T78834 HIV-IN-7

HIF/HIF Prolyl-Hydroxylase Chromatin/Epigenetic; Metabolism
Axl-IN-16(Compound 4)为Axl抑制剂,能够抑制Axl表达及抑制HIF活性,并诱导金针菇子实体形成。Axl-IN-16可通过分离红血球菌与猴头菇的“子实体液(FL)”得到。
T64048 HIV-IN-5

Others Others
HIV-IN-5 (compound 5r) 是 HIV-1 的有效抑制剂 (IC50: 0.16 μM)。HIV-IN-5 能够与 NNIBP (NNRTIs (非核苷逆转录酶抑制剂) 结合位点) 相结合。HIV-IN-5 能够抑制 HIV DNA 依赖的 DNA 聚合作用 (IC50: 2.18 μM)。
T76603 HIV-IN petide

HIV-IN petide 是HIV-1蛋白酶 (Ki=50 nM) 的竞争性抑制剂。
T62978 HIV-IN-3

Others Others
HIV-IN-3 (Compound 22a) 是一种 HIV 的有效抑制剂 (IC50: 1.5 μM)。HIV-IN-3 具有潜力进行 HIV 相关疾病的研究。
T76490 Fluorescent HIV Substrate

FluorescentHIVSubstrate 是 HIV 底物。
T82194 HIV-IN-9

Others Others
HIV-IN-9 (Compound 2b)为一种HIV抑制剂,IC50值为6.65 μg/mL,对HIV-RT展现出高度结合亲和力。此外,HIV-IN-9亦能抑制CYP3A4、CYP1A2、CYP2C1和CYP2D6等多种酶。
T2332 Elvitegravir

埃替格韦,GS-9137,EVG,D06677,JTK-303

HIV Protease Microbiology/Virology; Proteases/Proteasome
Elvitegravir (JTK-303) 是一种人类免疫缺陷病毒整合酶链转移抑制剂,作用于 HIV-1IIIB、HIV-2EHO 和 HIV-2ROD,IC50分别为 0.7 nM、2.8 nM 和 1.4 nM。
T74939 HIV protease-IN-1

Others Others
HIVprotease-IN-1 (compound 1·succinate) 是一种有效的HIV 蛋白酶 (HIV protease) 非肽抑制剂,可用于艾滋病的研究。
T76485 HIV Protease Substrate I

HIV ProteaseSubstrate I 是HIV-1蛋白酶的显色底物。HIV ProteaseSubstrate I 具有HIV 蛋白酶的裂解位点。
T4493 Bictegravir

GS-9883

HIV Protease Microbiology/Virology; Proteases/Proteasome
Bictegravir (GS-9883) 是一种 HIV-1 整合酶抑制剂,其IC50值为 7.5 nM。
T76511 HIV Protease Substrate IV

HIV ProteaseSubstrate IV 是 HIV 蛋白酶的底物。HIV ProteaseSubstrate IV 可用于检测 HIV(人类免疫缺陷病毒)-1 蛋白酶的活性。
T62319 HIV-1 inhibitor-44

Others Others
HIV-1 inhibitor-44 (compound 11l) 是一种 HIV-1 逆转录酶抑制剂,表现出抗野生型 HIV-1 菌株的活性 (EC50: 0.209 μM)。
T62353 HIV-1 inhibitor-33

Others Others
HIV-1 inhibitor-33 (compound 5n) 是一种有效的、选择性的 HIV-1 抑制剂,作用于 HIV-1 (EC50: 8.6 nM)、MT-4 细胞 (CC50: 18 μM)。HIV-1 inhibitor-33 能够用于研究艾滋病。
T62287 HIV-1 inhibitor-42

Others Others
HIV-1 inhibitor-42 (compound 5b) 是一种 HIV-1 的有效抑制剂 (IC50: 0.06 μM)。HIV-1 inhibitor-42 能够抑制 HIV-1 RT RNA 依赖性 DNA 聚合酶 (IC50: 0.518 μM) 和 DNA 依赖性 DNA 聚合酶 (IC50: 0.072 μM) 。
T63687 HIV-1 inhibitor-18

Others Others
HIV-1 inhibitor-18 是 HIV-1 衣壳的有效抑制剂,能够作用于 HIV-1 NL4-3 病毒株 (EC50: 5.14 μM),并表现出一定的细胞毒性 (MT-4CC50>9.51)。
T61134 HIV-1 inhibitor-36

Others Others
HIV-1 inhibitor-36 (Compound 2) is a potent HIV-1 inhibitor with significant potential as a novel latency reversing agent [1].
T64009 HIV-1 inhibitor-23

Others Others
HIV-1 inhibitor-23 是 HIV-1 非核苷逆转录酶的高效抑制剂,能够作用于野生型 HIV-1 (EC50: 24.9 nM) 和突变病毒株 K103N (EC50: 10.4 nM)。HIV-1 inhibitor-23 的细胞毒性较低 (CC50> 221 μM),并具有良好的体外微粒体稳定性。
T78749 HIV-1 inhibitor-57

Others Others
HIV-1 inhibitor-57(Compound 12g)是抗HIV药物。该化合物对野生型及五种常见NNRTI耐药HIV-1株均表现出抗病毒活性,具有0.024至0.0010 μM的EC 50值。HIV-1 inhibitor-57能够与HIV-1RT的结合位点附近残基形成附加相互作用。
T60342 HIV-1 inhibitor-47

Others Others
HIV-1 inhibitor-47 is a compound that effectively inhibits HIV-1 by preventing the vif-dependent degradation of human APOBEC3G. It has a notable inhibition effect, with an IC50 value of 14.33 μM. Additionally, HIV-1 inhibitor-47 is involved in the synthesis of derivatives of 1-(2-pyrimidinyl)piperazine, which have the potential to exhibit antianxiety, antidepressant, and antipsychotic effects [1] [2] [3].
T72565 HIV-1 inhibitor-52

Others Others
HIV-1inhibitor-52 是高效广谱HIV-1活性抑制剂,具备对 WT HIV-1、HIV-1 V370A、HIV-1 ΔV370、HIV-1 V362I/V370A、HIV-1 T332S/V362I/prR41G、HIV-1 A326T/V362I/V370A、和HIV-1 R361K/V362I/L363M 等变异株的强效抑制作用,其EC50值范围为 1.6 nM至6.4 nM。
T63813 HIV-1 inhibitor-39

Others Others
HIV-1 inhibitor-39 是 HIV-1 的有效抑制剂 (EC50>112.88 μM)。 HIV-1 inhibitor-39 具有抗 RT (HIV-1 逆转录酶) 作用 (IC50: 15.75 μM)。HIV-1 inhibitor-39 对 MT-4 细胞表现出细胞毒性 (CC50: 112.9 μM)。
T62431 HIV-1 inhibitor-25

Others Others
HIV-1 inhibitor-25 (compound R-12a) 是一种 HIV-1 逆转录 (HIV-1 RT) 的高效抑制剂 (IC50: 0.1061 nM)。HIV-1 inhibitor-25 对野生型 HIV-1 表现出较高的抗病毒效果,其 EC50 值为 13.6 nM,且细胞毒性较低 (对 MT-4 细胞的 CC50 值为 33.13 μM)。HIV-1 inhibitor-25 也能够抑制 HIV-1 突变株 (L100I, K103 N, Y181C, Y188L, E138K, F227L+V106A),EC50=0.1961 ~ 5.8136 μM。HIV-1 inhibitor-25 能够用于研究艾滋病。

化合物

HIV-1 Inhibitor 18A
Cat.No: T24141
Synonym: HIV-1 Inhibitor-18A
Target: HIV Protease
HIV-1 Rev (34-50)
Cat.No: TP1149
Synonym: HIV-1 Rev 34-50,HIV-1 rev Protein (34-50)
Target: HIV Protease
HIV-1 inhibitor-54
Cat.No: T67833
Synonym:
Target: HIV Protease
HIV-1 Nef-IN-1
Cat.No: T9039
Synonym:
Target: HIV Protease
HIV-1 inhibitor-6 
Cat.No: T9854
Synonym: 3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-
Target: HIV Protease
HIV-IN-6
Cat.No: T61793
Synonym:
Target: HIV Protease
HIV gag peptide (197-205)
Cat.No: TP1637
Synonym: HIV gag peptide 197-205
Target:
HIV p17 Gag (77-85)
Cat.No: TP1674
Synonym: HIV p17 Gag 77-85
Target:
(Cys47)-HIV-1 tat Protein (47-57)
Cat.No: T40719
Synonym: (Cys47)-HIV-1 tat Protein (47-57)
Target:
HIV-1 integrase inhibitor 8
Cat.No: T60742
Synonym:
Target: HIV Protease
HIV Protease Substrate 1
Cat.No: T39729
Synonym:
Target:
MPG, HIV related
Cat.No: TP1743
Synonym:
Target:
HIV-1 inhibitor-3
Cat.No: T11564
Synonym:
Target: Others
HIV-1 integrase inhibitor
Cat.No: T11566
Synonym:
Target: Others
HIV-1 integrase inhibitor 7
Cat.No: T11565
Synonym:
Target: Others
HIV-1 integrase inhibitor 4
Cat.No: T11568
Synonym:
Target: Others
HIV-1 TAT 48-60
Cat.No: TP1776
Synonym:
Target:
CK176
Cat.No: T27030
Synonym: HIV-1 inhibitor-34,HIV-1 inhibitor 34,CK 176,CK-176,HIV-1 inhibitor34
Target: Others
HIV-1 integrase inhibitor 3
Cat.No: T11567
Synonym:
Target: Others
HIV-1, HIV-2 Protease Substrate
Cat.No: T76502
Synonym:
Target:
LEDGIN6
Cat.No: T15483
Synonym: HIV-1 integrase inhibitor 2
Target: Others
Des(benzylpyridyl) Atazanavi
Cat.No: T1883
Synonym:
Target: HIV Protease
TAT
Cat.No: TP1809
Synonym:
Target: HIV Protease
Cys-TAT(47-57)
Cat.No: TP1185
Synonym: Cys-[HIV-Tat (47-57)]
Target:
HIV-IN-2
Cat.No: T74282
Synonym:
Target: Others
HIV-IN-8
Cat.No: T79974
Synonym:
Target: Others
HIV Peptide T
Cat.No: T77792
Synonym:
Target: Others
HIV-IN-4
Cat.No: T60426
Synonym:
Target: Others
HIV-IN-7
Cat.No: T78834
Synonym:
Target: HIF/HIF Prolyl-Hydroxylase
HIV-IN-5
Cat.No: T64048
Synonym:
Target: Others
HIV-IN petide
Cat.No: T76603
Synonym:
Target:
HIV-IN-3
Cat.No: T62978
Synonym:
Target: Others
Fluorescent HIV Substrate
Cat.No: T76490
Synonym:
Target:
HIV-IN-9
Cat.No: T82194
Synonym:
Target: Others
Elvitegravir
Cat.No: T2332
Synonym: 埃替格韦,GS-9137,EVG,D06677,JTK-303
Target: HIV Protease
HIV protease-IN-1
Cat.No: T74939
Synonym:
Target: Others
HIV Protease Substrate I
Cat.No: T76485
Synonym:
Target:
Bictegravir
Cat.No: T4493
Synonym: GS-9883
Target: HIV Protease
HIV Protease Substrate IV
Cat.No: T76511
Synonym:
Target:
HIV-1 inhibitor-44
Cat.No: T62319
Synonym:
Target: Others
HIV-1 inhibitor-33
Cat.No: T62353
Synonym:
Target: Others
HIV-1 inhibitor-42
Cat.No: T62287
Synonym:
Target: Others
HIV-1 inhibitor-18
Cat.No: T63687
Synonym:
Target: Others
HIV-1 inhibitor-36
Cat.No: T61134
Synonym:
Target: Others
HIV-1 inhibitor-23
Cat.No: T64009
Synonym:
Target: Others
HIV-1 inhibitor-57
Cat.No: T78749
Synonym:
Target: Others
HIV-1 inhibitor-47
Cat.No: T60342
Synonym:
Target: Others
HIV-1 inhibitor-52
Cat.No: T72565
Synonym:
Target: Others
HIV-1 inhibitor-39
Cat.No: T63813
Synonym:
Target: Others
HIV-1 inhibitor-25
Cat.No: T62431
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
TN2283 Tripterifordin

HIV Protease Microbiology/Virology; Proteases/Proteasome
Tripterifordin 在 H9 淋巴细胞中显示出抗 HIV 复制活性,EC50值为 3100 nM。
T5783 Rosamultin

野蔷薇苷,罗莎白素

Antioxidant; HIV Protease Microbiology/Virology; oxidation-reduction; Proteases/Proteasome
Rosamultin 是从Potentilla anserina L 分离的 19 α-羟基型三萜。它抑制 HIV-1 蛋白酶,具有抗氧化、抗炎和镇痛作用。
TN1059 Ganoderic acid B

IL Receptor; HIV Protease; JAK; STAT Angiogenesis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Microbiology/Virology; Proteases/Proteasome; Stem Cells
Ganoderic acid B 是从灵芝中分离的一种三萜类天然产物。它是端粒酶抑制剂,抑制 Epstein-Barr 病毒抗原的活化。它是 HIV-1 蛋白酶抑制剂。
T6377 Aloperine

Apoptosis; Virus Protease; HIV Protease; Antibiotic; Autophagy Apoptosis; Autophagy; Microbiology/Virology; Proteases/Proteasome
Aloperine 是一种在苦参类植物中的生物碱,其具有抗癌,抗炎、抗肿瘤和抗病毒特性,可用于研究过敏性接触性皮炎湿疹和其他皮肤炎症。
TN1103 Diphyllin

山荷叶素,二叶草素

ATPase; Proton pump; Influenza Virus; HIV Protease Membrane transporter/Ion channel; Microbiology/Virology; Proteases/Proteasome
Diphyllin 是一种从Justicia procumbens 中分离的芳基萘木脂素,是HIV-1的有效抑制剂,IC50 为 0.38 μM。它是V-ATPase 抑制剂,IC50值为 17 nM,可抑制人破骨细胞中的溶酶体酸化。它抑制NO 产生,IC50值为 50 μM ,具有抗癌和抗炎活性。
T12651 Rabdosiin

(+)-Rabdosiin

Others Others
Rabdosiin ((+)-Rabdosiin) 是一种分离自 Rabdosia japonicaHara 中的咖啡酸四聚体,具有抗过敏、抗 HIV 和抑制 DNA 拓扑异构酶作用。
T4S1383 Escin IA

Aescin IA,Escin IA;Aescin IA,Escin IA

HIV Protease Microbiology/Virology; Proteases/Proteasome
Escin IA (Escin IA;Aescin IA);Aescin IA 是从马蹄中七叶树分离出的一种三萜皂苷,抑制HIV-1蛋白酶,IC50值为 35 μM。它具有抗 TNBC 转移活性,其作用机制涉及通过下调 LOXL2 表达抑制上皮-间质转化过程。
T6S2391 L-Chicoric Acid

(-)-Chicoric acid,trans-Caffeoyltartaric acid,Chicoric acid,L-菊苣酸,dicaffeoyltartaric acid,菊苣酸

Others; HIV Protease Microbiology/Virology; Others; Proteases/Proteasome
L-Chicoric Acid (trans-Caffeoyltartaric acid) 是一种二咖啡酰酒石酸,是一种选择性可逆的 HIV-1 整合酶抑制剂,IC50约为 100 nM。它还可抑制 HIV-1 复制。
TQ0217 Gomisin G

戈米辛G,戈米辛 G

P450; HIV Protease Metabolism; Microbiology/Virology; Proteases/Proteasome
Gomisin G 是一种有抗HIV 活性的天然产物。
T4S1387 Isoescin IA

七叶皂苷C,异七叶皂苷 IA

HIV Protease Microbiology/Virology; Proteases/Proteasome
Isoescin IA 是一种从七叶树种子中分离出来的三萜皂苷。它具有抗HIV-1蛋白酶活性。
T0474 Erythromycin ethylsuccinate

EES,琥乙红霉素

ribosome; HIV Protease; Antibacterial; Antibiotic; Autophagy Autophagy; Microbiology/Virology; Proteases/Proteasome
Erythromycin ethylsuccinate (EES) 是一种由红链霉菌产生的大环内酯类抗生素,有潜力用于多种细菌感染。它具有抗 HIV-1病毒活性。
Fr16741 Oxindole

2-吲哚酮,板蓝根,Indolin-2-one

Others; HIV Protease Microbiology/Virology; Others; Proteases/Proteasome
Oxindole (Indolin-2-one) 是一种芳族杂环砌块,其衍生物是激酶抑制剂研究中的主要成分。
T2942 Psoralen

Ficusin,Furocoumarin,补骨脂素,psoralene

Apoptosis; Influenza Virus; HIV Protease; DNA/RNA Synthesis Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Proteases/Proteasome
Psoralen (Ficusin) 是从补骨脂种子中提取的一种香豆素。它具有如抗癌、抗氧化、抗抑郁、抗癌、抗菌、抗病毒等多种生物学特性。
T2865 Oleanolic Acid

Oleanic acid,Caryophyllin,齐墩果酸

HIV Protease; Endogenous Metabolite; Antibiotic; Autophagy Autophagy; Metabolism; Microbiology/Virology; Proteases/Proteasome
Oleanolic Acid (Caryophyllin) 是具有抗癌活性的一种天然产物。
T3822 Bellidifolin

Bellidifoline,龙胆山酮酚,Bellidifolium,雏菊叶龙胆酮

Others; HIV Protease Microbiology/Virology; Others; Proteases/Proteasome
Bellidifolin (Bellidifoline) 是从獐牙菜的茎中提取的一种呫吨酮,它能作为病毒蛋白 R 的抑制剂,具有保肝、降血糖、抗炎、抗氧化、抗肿瘤作用。
T0966 Sennoside A

番泻苷A,NSC 112929,番泻苷 A

MAO; HIV Protease Metabolism; Microbiology/Virology; Neuroscience; Proteases/Proteasome
Sennoside A (NSC-112929) 是在番泻叶的叶子和豆荚中大量发现的蒽醌苷,抑制 HIV-1 复制。
T6841 Fumagillin

NSC9168,烟曲霉素,Amebacilin

Others; HIV Protease; Antibiotic; Parasite Microbiology/Virology; Others; Proteases/Proteasome
Fumagillin (Amebacilin) 由烟曲霉菌中提取的一种抗菌药,有抗阿米巴活性。它通过抑制 HIV-1 viral protein R 活性来抑制 HIV‐1感染。
T8689 Chloroquine

CQ,氯喹

SARS-CoV; TLR; HIV Protease; Antibiotic; Parasite; Autophagy Autophagy; Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
Chloroquine 是一种 Toll 样受体抑制剂,可以抑制自噬。Chloroquine 具有抗疟疾和抗炎活性,广泛用于治疗疟疾和类风湿性关节炎。Chloroquine 还具有抗 SARS-CoV-2 (COVID-19) 活性、抗 HIV-1 活性。
T8116 Azulene

甘菊蓝,奥苷菊环,Bicyclo[5.3.0]Decapentaene

Others; HIV Protease Microbiology/Virology; Others; Proteases/Proteasome
Azulene (Bicyclo[5.3.0]Decapentaene) 是萘的异构体,具有高抗HIV 活性。它是从洋甘菊精油中分离出来的一种化学支架。
T2177 Kaempferol

Kempferol,山柰酚,山奈酚,Robigenin

Apoptosis; Estrogen Receptor/ERR; Mitophagy; Estrogen/progestogen Receptor; HIV Protease; Endogenous Metabolite; Parasite; Autophagy Apoptosis; Autophagy; Endocrinology/Hormones; Metabolism; Microbiology/Virology; Proteases/Proteasome
Kaempferol (Robigenin) 属于天然类黄酮,是一种 ERRα 和 ERRγ 的反向激动剂。Kaempferol 具有抗肿瘤、抗炎、抗氧化、抗菌和抗病毒等多种活性。
T2S0731 Trilobatin

三叶苷,三叶甙,P-Phlorizin

Amylase Metabolism
Trilobatin (P-Phlorizin) 是源自Lithocarpus polystachyusRehd 的甜味剂,是一种HIV-1抑制剂,靶向 Gp41 包膜蛋白,具有神经保护作用。它还是SGLT1/2抑制剂,可选择性诱导人肝母细胞瘤细胞增殖。
T0492 Dimethyl fumarate

富马酸二甲酯,DMF

Reactive Oxygen Species; HIV Protease; Nrf2; Endogenous Metabolite; Autophagy Autophagy; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome
Dimethyl fumarate (DMF) 是具有口服活性且可透过血脑屏障的Nrf2激活剂,可诱导抗氧化剂基因表达上调。它是一种富马酸盐衍生物,可作抗炎和免疫调节剂,可研究多发性硬化症。
T4962 Zingibroside R1

Ginsenoside Z-R1,姜状三七皂苷R1,姜状三七苷R1

HIV Protease Microbiology/Virology; Proteases/Proteasome
Zingibroside R1 (Ginsenoside Z-R1) 是分离自Panax japonicasC. A. Meyer 根部的一种三萜皂苷,有HIV-1、抗肿瘤和抗血管生成活性。它对 EAT 细胞的 2-脱氧-D-葡萄糖的摄取具有抑制作用,IC50值为91.3 μM。
TN2158 Robinetin

3,3',4',5',7-Pentahydroxyflavone,洋槐黄素

Anti-infection; HIV Protease; Antibacterial Microbiology/Virology; Proteases/Proteasome
Robinetin (3,3',4',5',7-Pentahydroxyflavone) 是一种天然黄酮,具有显著的“两种颜色”固有荧光特性。它具有抗真菌、抗病毒、抗菌、抗突变、抗氧化和抗自由基活性,高效抑制 EYPC 膜脂质过氧化和 HbA 糖基化。
T0200 α-Lipoic Acid

Thioctic acid,DL-α-Lipoic acid,(±)-α-Lipoic acid,α-硫辛酸,硫辛酸

Apoptosis; NF-κB; HIV Protease; Mitochondrial Metabolism; Endogenous Metabolite Apoptosis; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome
α-Lipoic Acid (DL-α-Lipoic acid) 是线粒体酶复合物的重要辅助因子,是一种抗氧化剂,可抑制NF-κB 依赖性的HIV-1LTR 活化。它还可诱导内质网应激介导的肝癌细胞凋亡。
T7991 2-Hydroxycinnamic acid

邻羟基肉桂酸(邻香豆酸),(E)-3-(2-羟基苯基)丙烯酸

Others; SARS-CoV; HIV Protease Microbiology/Virology; Others; Proteases/Proteasome
2-Hydroxycinnamic acid 是从肉桂的甲醇提取物中分离出的一种天然产物,具有光氧化活性。它对HIV/SARS-CoV S 假病毒的感染具有抑制作用,IC50为 0.3 mM。
T2789 Scutellarin

黄岑素,野黄芩苷,Breviscapin,Breviscapinun,Breviscapine,Scutellarein-7-glucuronide

Akt; HIV Protease; STAT Cytoskeletal Signaling; JAK/STAT signaling; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Stem Cells
Scutellarin (Scutellarein-7-glucuronide) 是从黄芩中分离的黄酮,可抑制破骨细胞中 RANKL 介导的 MAPK 和 NF-κB 信号通路,并下调 HCC 细胞中的 STAT3/Girdin/Akt 信号通路。
T1284 Megestrol acetate

SC10363,醋酸甲地孕酮,BDH1298

Glucocorticoid Receptor; Estrogen/progestogen Receptor; Progesterone Receptor; HIV Protease; Autophagy Autophagy; Endocrinology/Hormones; Microbiology/Virology; Others; Proteases/Proteasome
Megestrol acetate (BDH1298) 是具有口服活性的合成孕激素。它还具有抗雄激素特性,可用于治疗厌食症和恶病质。
T1131 Ivermectin

MK-933,伊维菌素

Mitophagy; GluCls; P2X Receptor; SARS-CoV; HIV Protease; Antibiotic; Parasite; Autophagy; HSV Autophagy; Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience; Proteases/Proteasome
Ivermectin (MK-933) 是谷氨酸门控氯离子通道激活剂,具有抗寄生虫活性。它特异性抑制Impα/β1 介导的核导入,还抑制牛疱疹病毒 1 复制并抑制BoHV-1DNA 聚合酶的核输入。它具有很强的抗病毒活性。它也是P2X4和 α7nAChRs 的正异构效应物。
T2728 Limonin

Dictamnolactone,Limonoic acid 3,19:16,17 dilactone,柠檬苦素,Obaculactone,Citrolimonin

Apoptosis; HIV Protease; Endogenous Metabolite Apoptosis; Metabolism; Microbiology/Virology; Proteases/Proteasome
Limonin (Citrolimonin) 是柑橘类水果中富含的一种三萜类天然产物,具有抗病毒和抗肿瘤活性。
T3122 Fangchinoline

Tetrandrine B,防己诺林碱,(+)-Limacine,Hanfangichin B,防己醇灵,(+)-Fangchinoline

Apoptosis; FAK; HIV Protease; Autophagy Angiogenesis; Apoptosis; Autophagy; Cytoskeletal Signaling; Microbiology/Virology; Proteases/Proteasome; Tyrosine Kinase/Adaptors
Fangchinoline (Tetrandrine B) 是从Stephaniatetrandra 中分离出来的,一种具有广泛生物学活性的天然产物。它是新型HIV-1抑制剂,通过损害 gp160 蛋白水解过程来抑制 HIV-1 复制。它靶向Focal adhesion kinase (FAK)并抑制肿瘤细胞中 FAK 介导的的信号传导途径。
T16791 Rottlerin

Mallotoxin,NSC 56346,粗糠柴苦素,NSC 94525

CaMK; Apoptosis; Others; HIV Protease; PKA; PKC; Autophagy Apoptosis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling; Microbiology/Virology; Neuroscience; Others; Proteases/Proteasome; Tyrosine Kinase/Adaptors
Rottlerin (NSC-56346) 是一种从Mallotus Philippinensis 中得到的天然产物, 是 PKC 的特异性抑制剂,抑制HIV-1整合和狂犬病病毒感染。它通过活化 caspase 3 诱导细胞凋亡.
T22468 1-Deoxymannojirimycin hydrochloride

Others; Influenza Virus; HIV Protease Microbiology/Virology; Others; Proteases/Proteasome
1-Deoxymannojirimycin hydrochloride 是一种选择性的 α1,2-甘露糖苷酶抑制剂,IC50值为 20 μM。它还抑制 HIV-1 毒株,抗病毒活性较差。
T3730 Methyl gallate

NSC 363001,Gallicin,Gallic acid methyl ester,Gallincin,没食子酸甲酯

Reactive Oxygen Species; HIV Protease; Reverse Transcriptase; Antibacterial Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome
Methyl gallate (Gallincin) 是具有抗氧化,抗癌和抗炎活性的植物酚类。它也可抑制细菌活性。它还具有抗HIV-1和HIV-1酶的抑制活性。
T5782 Bevirimat

YK FH312,MPC-4326,PA-457,贝韦立马

HIV Protease Microbiology/Virology; Proteases/Proteasome
Bevirimat (PA-457) 是一种 HIV-1 成熟抑制剂,可在病毒体成熟过程中阻断 Gag 衣壳 (CA) 前体 CA-SPI 裂解为成熟的 CA 蛋白。
T2775 Baicalin

黄芩苷,黄岑苷,Baicalein 7-O-β-D-glucuronide

NF-κB; HIV Protease; GABA Receptor; Autophagy Autophagy; Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience; NF-κB; Proteases/Proteasome
Baicalin (Baicalein 7-O-β-D-glucuronide) 是一种从黄芩中分离出来的脯氨酰内肽酶抑制剂,具有抗氧化、抗肿瘤、抗 HIV 的特性。
T2830 Betulinic acid

白桦脂酸,桦木酸,ALS-357,Lupatic acid,Betulic acid

Apoptosis; Mitophagy; NF-κB; HIV Protease; Topoisomerase; Endogenous Metabolite; Aminopeptidase; Autophagy Apoptosis; Autophagy; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome
Betulinic acid (ALS-357) 是从白桦树皮中分离出来的一种五环三萜类天然产物,是真核细胞拓扑异构酶 I 的抑制剂,IC50值为 5 μM,具有抗逆转录病毒、抗疟疾、抗癌和抗炎特性。
T0710 L-Cycloserine

Levcycloserine,Levcicloserina,(-)-Cycloserine,(S)-Cycloserine,Levcycloserinum,环丝氨酸,(S)-4-Amino-3-isoxazolidone

HIV Protease; GABA Receptor Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience; Proteases/Proteasome
L-Cycloserine ((-)-Cycloserine) 不可逆地抑制大肠杆菌以及各种动物大脑中的 GABA 吡哆醛 5'-磷酸依赖性转氨酶,导致体内抑制性神经递质 γ-氨基丁酸水平升高。
T0070 Pentoxifylline

Oxpentifylline,PTX,己酮可可碱,BL-191

HIV Protease; PDE; Adenosine Receptor; Autophagy Autophagy; GPCR/G Protein; Metabolism; Microbiology/Virology; Neuroscience; Proteases/Proteasome
Pentoxifylline (PTX) 是一种具有口服活性的磷酸二酯酶非选择性抑制剂,具有免疫调节、抗炎、抗纤溶、抗增殖和血液流变学改善作用。它可研究周围血管疾病、脑血管疾病和其他一些涉及局部微循环缺陷的疾病。
T3772 Maslinic acid

2α-Hydroxyoleanoic Acid,山楂酸,2α-Hydroxyoleanolic acid,Crategolic acid

NF-κB; HIV Protease; DNA/RNA Synthesis; Antibacterial Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; NF-κB; Proteases/Proteasome
Maslinic acid (Crategolic acid) 是一种 DNA 聚合酶 B 抑制剂,抑制 NF-κB p65的 DNA 结合活性并消除 IκB-α磷酸化。
T0194 Chloroquine phosphate

Chloroquine diphosphate,Aralen phosphate,磷酸氯喹,Chingamin phosphate

SARS-CoV; TLR; HIV Protease; Antibiotic; Parasite; Autophagy Autophagy; Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
Chloroquine phosphate (Aralen phosphate) 是广泛用于疟疾和类风湿性关节炎的抗疟疾和抗炎剂。它是autophagy 和toll-like receptors 抑制剂,有效抑制SARS-CoV-2(COVID-19) 感染 (EC50=1.13 μM)。
T3321 Oleanonic acid

3-Oxooleanolic acid,3-Oxoolean-12-en-28-oic Acid,Oleanonic Acid,齐墩果酮酸,3-Ketooleanolic Acid

HIV Protease Microbiology/Virology; Proteases/Proteasome
Oleanonic acid (3-Ketooleanolic Acid) 是一种三萜,可以抑制 HIV-1 对细胞的感染。它具有保肝作用,并具有抗肿瘤和抗病毒特性。
T5429 Theaflavin 3,3'-digallate

茶黄素-3,3'-双没食子酸,8-Gingerol,TFDG

Virus Protease; Antioxidant; HIV Protease; HSV Microbiology/Virology; oxidation-reduction; Proteases/Proteasome
Theaflavin 3,3'-digallate (8-Gingerol) 是一种寨卡病毒蛋白酶抑制剂,IC50为 2.3 μM。它直接与 ZIKVpro 结合并抑制 ZIKV 复制,可抑制 gp41 和 NS2B-3 蛋白酶的活性,并具有抗 HSV 和 HIV-1病毒活性。它是红茶中的主要多酚,有抗肿瘤作用。
T1125 Shikonin

NSC 252844,Isoarnebin 4,(+)-Shikonin,紫草素,Alkanna Red,C.I. 75535,Anchusa acid

TNF; NF-κB; Chloride channel; HIV Protease; PKM Apoptosis; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome
Shikonin (Anchusa acid) 属于天然产物,是一种 TMEM16A 氯离子通道抑制剂 (IC50=6.5 μM) 和选择性 PKM2 抑制剂。Shikonin 具有抗肿瘤、抗炎和伤口愈合活性。
T1020 Doxorubicin hydrochloride

Adriamycin,Doxorubicin (Adriamycin) HCl,Hydroxydaunorubicin hydrochloride,盐酸多柔比星,DOX hydrochloride,盐酸阿霉素,NSC 123127

Apoptosis; Mitophagy; HBV; HIV Protease; Topoisomerase; Antibacterial; Antibiotic; AMPK; Autophagy; ADC Cytotoxin Antibody-drug Conjugate/ADC Related; Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome
Doxorubicin hydrochloride (Adriamycin) 属于蒽环类抗生素,是人类 DNA 拓扑异构酶 I/II 抑制剂 (IC50=0.8/2.67 μM)。Doxorubicin hydrochloride 具有细胞毒性和抗肿瘤活性。Doxorubicin hydrochloride 可降低 AMPK 及其下游靶蛋白乙酰辅酶 A 羧化酶的磷酸化,还可诱导凋亡和自噬。
T7064 Valproic Acid

Sodium valproate,2-Propylpentanoic Acid,丙戊酸,VPA,Depakine,2-Propylvaleric Acid

Mitophagy; Gamma-secretase; HIV Protease; GABA Receptor; Sodium Channel; HDAC; Autophagy Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience; Proteases/Proteasome; Stem Cells
Valproic Acid (2-Propylpentanoic Acid) 是一种 HDAC 抑制剂,可抑制 HDAC1 活性,诱导 HDAC2 降解,具有口服活性。Valproic Acid 可以用于癫痫和躁郁症的研究。
T1456 Doxorubicin

Hydroxydaunorubicin,DOX,阿霉素,Adriamycin

Topoisomerase; AMPK; ADC Cytotoxin Antibody-drug Conjugate/ADC Related; Chromatin/Epigenetic; DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
Doxorubicin (Adriamycin) 是一种有细胞毒性的蒽环类抗生素,具有肿瘤化疗作用。它抑制DNA 拓扑异构酶 I 和拓扑异构酶 II,IC50分别为0.8 μM 和2.67 μM,从而抑制 DNA 复制。它下调AMPK 的基础磷酸化以及下游 acetyl-CoA 羧化酶。它诱导凋亡和自噬 。
TN6600 Kaempferol 3-O-(6''-galloyl)-beta-D-glucopyranoside

HIV Protease Microbiology/Virology; Proteases/Proteasome
Kaempferol 3-O-(6''-galloyl)-beta-D-glucopyranoside 是一种吡喃葡萄糖苷,对 HIV-2 RNase H 具有抑制作用,IC50 为 5.19 μM。
TL0006 Cichoric Acid

菊苣酸,Dicaffeoyltartaric acid,Chicoric Acid

Reactive Oxygen Species; HIV Protease Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome
Cichoric Acid (Dicaffeoyltartaric acid) 是一种天然化合物,具有抗氧化作用。
T4S1718 Punicalin

HBV; HIV Protease Microbiology/Virology; Proteases/Proteasome
Punicalin 是从Punica granatumL. 或Terminalia catappaL. 的叶子中分离的,一种可水解的单宁,具有抗炎活性。它是一种抗乙型肝炎病毒药物。
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天然产物

Tripterifordin
Cat.No: TN2283
Synonym:
Target: HIV Protease
Rosamultin
Cat.No: T5783
Synonym: 野蔷薇苷,罗莎白素
Target: Antioxidant, HIV Protease
Ganoderic acid B
Cat.No: TN1059
Synonym:
Target: IL Receptor, HIV Protease, JAK, STAT
Aloperine
Cat.No: T6377
Synonym:
Target: Apoptosis, Virus Protease, HIV Protease, Antibiotic, Autophagy
Diphyllin
Cat.No: TN1103
Synonym: 山荷叶素,二叶草素
Target: ATPase, Proton pump, Influenza Virus, HIV Protease
Rabdosiin
Cat.No: T12651
Synonym: (+)-Rabdosiin
Target: Others
Escin IA
Cat.No: T4S1383
Synonym: Aescin IA,Escin IA;Aescin IA,Escin IA
Target: HIV Protease
L-Chicoric Acid
Cat.No: T6S2391
Synonym: (-)-Chicoric acid,trans-Caffeoyltartaric acid,Chicoric acid,L-菊苣酸,dicaffeoyltartaric acid,菊苣酸
Target: Others, HIV Protease
Gomisin G
Cat.No: TQ0217
Synonym: 戈米辛G,戈米辛 G
Target: P450, HIV Protease
Isoescin IA
Cat.No: T4S1387
Synonym: 七叶皂苷C,异七叶皂苷 IA
Target: HIV Protease
Erythromycin ethylsuccinate
Cat.No: T0474
Synonym: EES,琥乙红霉素
Target: ribosome, HIV Protease, Antibacterial, Antibiotic, Autophagy
Oxindole
Cat.No: Fr16741
Synonym: 2-吲哚酮,板蓝根,Indolin-2-one
Target: Others, HIV Protease
Psoralen
Cat.No: T2942
Synonym: Ficusin,Furocoumarin,补骨脂素,psoralene
Target: Apoptosis, Influenza Virus, HIV Protease, DNA/RNA Synthesis
Oleanolic Acid
Cat.No: T2865
Synonym: Oleanic acid,Caryophyllin,齐墩果酸
Target: HIV Protease, Endogenous Metabolite, Antibiotic, Autophagy
Bellidifolin
Cat.No: T3822
Synonym: Bellidifoline,龙胆山酮酚,Bellidifolium,雏菊叶龙胆酮
Target: Others, HIV Protease
Sennoside A
Cat.No: T0966
Synonym: 番泻苷A,NSC 112929,番泻苷 A
Target: MAO, HIV Protease
Fumagillin
Cat.No: T6841
Synonym: NSC9168,烟曲霉素,Amebacilin
Target: Others, HIV Protease, Antibiotic, Parasite
Chloroquine
Cat.No: T8689
Synonym: CQ,氯喹
Target: SARS-CoV, TLR, HIV Protease, Antibiotic, Parasite, Autophagy
Azulene
Cat.No: T8116
Synonym: 甘菊蓝,奥苷菊环,Bicyclo[5.3.0]Decapentaene
Target: Others, HIV Protease
Kaempferol
Cat.No: T2177
Synonym: Kempferol,山柰酚,山奈酚,Robigenin
Target: Apoptosis, Estrogen Receptor/ERR, Mitophagy, Estrogen/progestogen Receptor, HIV Protease, Endogenous Metabolite, Parasite, Autophagy
Trilobatin
Cat.No: T2S0731
Synonym: 三叶苷,三叶甙,P-Phlorizin
Target: Amylase
Dimethyl fumarate
Cat.No: T0492
Synonym: 富马酸二甲酯,DMF
Target: Reactive Oxygen Species, HIV Protease, Nrf2, Endogenous Metabolite, Autophagy
Zingibroside R1
Cat.No: T4962
Synonym: Ginsenoside Z-R1,姜状三七皂苷R1,姜状三七苷R1
Target: HIV Protease
Robinetin
Cat.No: TN2158
Synonym: 3,3',4',5',7-Pentahydroxyflavone,洋槐黄素
Target: Anti-infection, HIV Protease, Antibacterial
α-Lipoic Acid
Cat.No: T0200
Synonym: Thioctic acid,DL-α-Lipoic acid,(±)-α-Lipoic acid,α-硫辛酸,硫辛酸
Target: Apoptosis, NF-κB, HIV Protease, Mitochondrial Metabolism, Endogenous Metabolite
2-Hydroxycinnamic acid
Cat.No: T7991
Synonym: 邻羟基肉桂酸(邻香豆酸),(E)-3-(2-羟基苯基)丙烯酸
Target: Others, SARS-CoV, HIV Protease
Scutellarin
Cat.No: T2789
Synonym: 黄岑素,野黄芩苷,Breviscapin,Breviscapinun,Breviscapine,Scutellarein-7-glucuronide
Target: Akt, HIV Protease, STAT
Megestrol acetate
Cat.No: T1284
Synonym: SC10363,醋酸甲地孕酮,BDH1298
Target: Glucocorticoid Receptor, Estrogen/progestogen Receptor, Progesterone Receptor, HIV Protease, Autophagy
Ivermectin
Cat.No: T1131
Synonym: MK-933,伊维菌素
Target: Mitophagy, GluCls, P2X Receptor, SARS-CoV, HIV Protease, Antibiotic, Parasite, Autophagy, HSV
Limonin
Cat.No: T2728
Synonym: Dictamnolactone,Limonoic acid 3,19:16,17 dilactone,柠檬苦素,Obaculactone,Citrolimonin
Target: Apoptosis, HIV Protease, Endogenous Metabolite
Fangchinoline
Cat.No: T3122
Synonym: Tetrandrine B,防己诺林碱,(+)-Limacine,Hanfangichin B,防己醇灵,(+)-Fangchinoline
Target: Apoptosis, FAK, HIV Protease, Autophagy
Rottlerin
Cat.No: T16791
Synonym: Mallotoxin,NSC 56346,粗糠柴苦素,NSC 94525
Target: CaMK, Apoptosis, Others, HIV Protease, PKA, PKC, Autophagy
1-Deoxymannojirimycin hydrochloride
Cat.No: T22468
Synonym:
Target: Others, Influenza Virus, HIV Protease
Methyl gallate
Cat.No: T3730
Synonym: NSC 363001,Gallicin,Gallic acid methyl ester,Gallincin,没食子酸甲酯
Target: Reactive Oxygen Species, HIV Protease, Reverse Transcriptase, Antibacterial
Bevirimat
Cat.No: T5782
Synonym: YK FH312,MPC-4326,PA-457,贝韦立马
Target: HIV Protease
Baicalin
Cat.No: T2775
Synonym: 黄芩苷,黄岑苷,Baicalein 7-O-β-D-glucuronide
Target: NF-κB, HIV Protease, GABA Receptor, Autophagy
Betulinic acid
Cat.No: T2830
Synonym: 白桦脂酸,桦木酸,ALS-357,Lupatic acid,Betulic acid
Target: Apoptosis, Mitophagy, NF-κB, HIV Protease, Topoisomerase, Endogenous Metabolite, Aminopeptidase, Autophagy
L-Cycloserine
Cat.No: T0710
Synonym: Levcycloserine,Levcicloserina,(-)-Cycloserine,(S)-Cycloserine,Levcycloserinum,环丝氨酸,(S)-4-Amino-3-isoxazolidone
Target: HIV Protease, GABA Receptor
Pentoxifylline
Cat.No: T0070
Synonym: Oxpentifylline,PTX,己酮可可碱,BL-191
Target: HIV Protease, PDE, Adenosine Receptor, Autophagy
Maslinic acid
Cat.No: T3772
Synonym: 2α-Hydroxyoleanoic Acid,山楂酸,2α-Hydroxyoleanolic acid,Crategolic acid
Target: NF-κB, HIV Protease, DNA/RNA Synthesis, Antibacterial
Chloroquine phosphate
Cat.No: T0194
Synonym: Chloroquine diphosphate,Aralen phosphate,磷酸氯喹,Chingamin phosphate
Target: SARS-CoV, TLR, HIV Protease, Antibiotic, Parasite, Autophagy
Oleanonic acid
Cat.No: T3321
Synonym: 3-Oxooleanolic acid,3-Oxoolean-12-en-28-oic Acid,Oleanonic Acid,齐墩果酮酸,3-Ketooleanolic Acid
Target: HIV Protease
Theaflavin 3,3'-digallate
Cat.No: T5429
Synonym: 茶黄素-3,3'-双没食子酸,8-Gingerol,TFDG
Target: Virus Protease, Antioxidant, HIV Protease, HSV
Shikonin
Cat.No: T1125
Synonym: NSC 252844,Isoarnebin 4,(+)-Shikonin,紫草素,Alkanna Red,C.I. 75535,Anchusa acid
Target: TNF, NF-κB, Chloride channel, HIV Protease, PKM
Doxorubicin hydrochloride
Cat.No: T1020
Synonym: Adriamycin,Doxorubicin (Adriamycin) HCl,Hydroxydaunorubicin hydrochloride,盐酸多柔比星,DOX hydrochloride,盐酸阿霉素,NSC 123127
Target: Apoptosis, Mitophagy, HBV, HIV Protease, Topoisomerase, Antibacterial, Antibiotic, AMPK, Autophagy, ADC Cytotoxin
Valproic Acid
Cat.No: T7064
Synonym: Sodium valproate,2-Propylpentanoic Acid,丙戊酸,VPA,Depakine,2-Propylvaleric Acid
Target: Mitophagy, Gamma-secretase, HIV Protease, GABA Receptor, Sodium Channel, HDAC, Autophagy
Doxorubicin
Cat.No: T1456
Synonym: Hydroxydaunorubicin,DOX,阿霉素,Adriamycin
Target: Topoisomerase, AMPK, ADC Cytotoxin
Kaempferol 3-O-(6''-galloyl)-beta-D-glucopyranoside
Cat.No: TN6600
Synonym:
Target: HIV Protease
Cichoric Acid
Cat.No: TL0006
Synonym: 菊苣酸,Dicaffeoyltartaric acid,Chicoric Acid
Target: Reactive Oxygen Species, HIV Protease
Punicalin
Cat.No: T4S1718
Synonym:
Target: HBV, HIV Protease
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Cat. No. Product Name Species Expression System
TMPY-02882 HIV-1 (group M, subtype CRF07_BC) gp140 Protein (His)

CUB domain containing protein 1

HIV HEK293 Cells
HIV-1 (group M, subtype CRF07_BC) gp140 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 78.2 kDa.
TMPY-01373 HIV-1 (group M, subtype CRF07_BC) gp120 Protein (His)

HIV HEK293 Cells
HIV-1 (group M, subtype CRF07_BC) gp120 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.8 kDa and the accession number is I6TSC9.
TMPY-01552 HIV-1 (group M, subtype B, strain 92418) p24 Protein (His)

Gag-p24

HIV E. coli
HIV-1 (group M, subtype B, strain 92418) p24 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 26.5 kDa and the accession number is B6DRA0.
TMPY-04192 HIV-1 (group M, subtype B, strain HXB2) p24 Protein (His)

Gag-p24

HIV E. coli
HIV-1 (group M, subtype B, strain HXB2) p24 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 26.5 kDa and the accession number is P04591.
TMPJ-01313 HIV-1 gp120 Protein (His)

Envelope glycoprotein gp120,Surface protein gp120,Glycoprote...

HIV HEK293 Cells
Envelope glycoprotein gp160 is single-pass type I membrane protein. The mature envelope protein (Env) consists of a homotrimer of non-covalently associated gp120-gp41 heterodimers. It is cleaved into the following 2 chains: glycoprotein 120 and transmembrane protein gp41. The resulting complex protrudes from the virus surface as a spike. The 17 amino acids long immunosuppressive region is present in many retroviral envelope proteins. Synthetic peptides derived from this relatively conserved sequ...
TMPH-01522 HIV-2 (subtype A, isolate ROD) Protein Vpx (His)

vpx,Viral protein X,X ORF protein,Protein Vpx

HIV-2 P. pastoris (Yeast)
Plays a role in nuclear translocation of the viral pre-integration complex (PIC), thus is required for the virus to infect non-dividing cells. Targets specific host proteins for degradation by the 26S proteasome. Acts by associating with the cellular CUL4A-DDB1 E3 ligase complex through direct interaction with host VPRPB/DCAF-1. This change in the E3 ligase substrate specificity results in the degradation of host SAMHD1. In turn, SAMHD1 depletion allows viral replication in host myeloid cells by...
TMPH-01521 HIV-2 (subtype A, isolate BEN) Protein Vpx (His)

Protein Vpx,X ORF protein,Viral protein X,vpx

HIV-2 E. coli
HIV-2 (subtype A, isolate BEN) Protein Vpx (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 17.2 kDa and the accession number is P18099.
TMPY-00426 HIV-1 (group P, strain RBF168) gp140 Protein (hFc)

CUB domain containing protein 1

HIV HEK293 Cells
HIV-1 (group P, strain RBF168) gp140 Protein (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 99.4 kDa and the accession number is D0VTQ8.
TMPY-04198 HIV-1 (group O, strain BCF06) p24 Protein (His)

Gag-p24

HIV E. coli
HIV-1 (group O, strain BCF06) p24 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 26.6 kDa and the accession number is C7G2S7.
TMPY-00427 HIV-1 (group P, strain RBF168) gp120 Protein (His)

HIV HEK293 Cells
HIV-1 (group P, strain RBF168) gp120 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.2 kDa and the accession number is D0VTQ8.
TMPY-01408 HIV-1 (group M, subtype CRF07_BC) gp140 Protein (hFc)

CUB domain containing protein 1

HIV HEK293 Cells
HIV-1 (group M, subtype CRF07_BC) gp140 Protein (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 98 kDa.
TMPY-04196 HIV-1 (group M, subtype D, strain NDK) p24 Protein (His)

Gag-p24

HIV E. coli
HIV-1 (group M, subtype D, strain NDK) p24 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 26.6 kDa and the accession number is P18800.
TMPY-04915 HIV-1 (group M, subtype B, Isolate MN) gp120 Protein (His)

HIV HEK293 Cells
HIV-1 (group M, subtype B, Isolate MN) gp120 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55.8 kDa and the accession number is Q9YUL5.
TMPY-00316 HIV-1 (group M, subtype B, isolate BAL) gp120 Protein (His)

HIV HEK293 Cells
HIV-1 (group M, subtype B, isolate BAL) gp120 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55.4 kDa and the accession number is Q03805.
TMPY-06486 HIV-1 (group M, subtype CRF07_BC) gp120 Protein (His), Biotinylated

HIV HEK293 Cells
HIV-1 (group M, subtype CRF07_BC) gp120 Protein (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.8 kDa and the accession number is AFM77980.1.
TMPY-01556 HIV-1 (group N, strain 06CM-U14296) p24 protein (His)

Gag-p24

HIV E. coli
HIV-1 (group N, strain 06CM-U14296) p24 protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 27 kDa.
TMPY-04061 HIV-2 (subtype CRF01_AB, strain 07JP_NMC716_clone_01) gp36 Protein (His & MBP)

GP36

HIV E. coli
HIV-2 (subtype CRF01_AB, strain 07JP_NMC716_clone_01) gp36 Protein (His & MBP) is expressed in E. coli expression system with His and MBP tag. The predicted molecular weight is 58.8 kDa and the accession number is L8B302.
TMPY-00425 HIV-1 (group M, subtype A, strain 92UG037.1) gp140 Protein (hFc)

CUB domain containing protein 1

HIV HEK293 Cells
HIV-1 (group M, subtype A, strain 92UG037.1) gp140 Protein (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 97.4 kDa and the accession number is P90249.
TMPY-04871 HIV-1 (group M, subtype C, strain 92BR025) gp140 Protein (Fc)

CUB domain containing protein 1

HIV HEK293 Cells
HIV-1 (group M, subtype C, strain 92BR025) gp140 Protein (Fc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 99.9 kDa and the accession number is O12164.
TMPY-04194 HIV-1 (group M, subtype C, strain 92BR025) p24 Protein (His)

Gag-p24

HIV E. coli
HIV-1 (group M, subtype C, strain 92BR025) p24 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 26.5 kDa and the accession number is O12157.
TMPH-01519 HIV-1 (group M, subtype C, isolate 92BR025) Protein Vpr (His & Myc)

Viral protein R,vpr,Protein Vpr,R ORF protein

HIV-1 E. coli
HIV-1 (group M, subtype C, isolate 92BR025) Protein Vpr (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.9 kDa and the accession number is O12160.
TMPY-00309 HIV-1 (group M, subtype B, strain SHIV-89.6P) gp120 Protein (His)

HIV HEK293 Cells
HIV-1 (group M, subtype B, strain SHIV-89.6P) gp120 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55.4 kDa and the accession number is O11407.
TMPY-01558 HIV-1 (group N, strain 06CM-U14296) gp160 (gp120 subunit) Protein (His)

HIV HEK293 Cells
HIV-1 (group N, strain 06CM-U14296) gp160 (gp120 subunit) Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.4 kDa.
TMPH-01520 HIV-1 (group M, subtype K, isolate 96CM-MP535) Protein Vpr (His & Myc)

vpr,R ORF protein,Protein Vpr,Viral protein R

HIV-1 E. coli
HIV-1 (group M, subtype K, isolate 96CM-MP535) Protein Vpr (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.8 kDa and the accession number is P0C1P2.
TMPY-00302 HIV-1 (group M, subtype A, isolate 92RW020) gp160 (gp120 subunit) Protein (His)

HIV HEK293 Cells
HIV-1 (group M, subtype A, isolate 92RW020) gp160 (gp120 subunit) Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52.2 kDa and the accession number is Q6BC58.
TMPY-04150 HIV-p51/RT-p51 (group M, subtype B (isolate HXB2) Gag-Pol polyprotein Protein (His)

Gag-Pol

HIV E. coli
HIV-p51/RT-p51 (group M, subtype B (isolate HXB2) Gag-Pol polyprotein Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 53.6 kDa and the accession number is P04585.
TMPY-04161 HIV-p66/RT-p66 (group M, subtype B (isolate HXB2) Gag-Pol polyprotein Protein (His)

Gag-Pol

HIV E. coli
HIV-p66/RT-p66 (group M, subtype B (isolate HXB2) Gag-Pol polyprotein Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 66.7 kDa and the accession number is P04585.
TMPY-01442 DMBT1 Protein, Human, Recombinant (His)

GP340,deleted in malignant brain tumors 1,muclin

Human HEK293 Cells
Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB domains, 14SRCR domains and 1ZP domain. It is highly expressed in alveolar and macrophage tissues. In some macrophages, expression is detected on the membrane, and in other macrophages, it is strongly expressed in the phagosome/phagolysosome compartments. Defects in DMBT1 are invo...
TMPH-00777 Griffithsin Protein, Griffithsia sp., Recombinant (X31S, His)

Griffithsin

Griffithsia E. coli
Mixed specificity lectin with anti-HIV activity. Binds to HIV envelope glycoproteins, including exterior membrane glycoprotein gp120, and inhibits viral entry into cells. Binding to gp120 is dependent on gp120 being glycosylated, and is inhibited by mannose, glucose and N-acetylglucosamine.
TMPH-00776 Griffithsin Protein, Griffithsia sp., Recombinant (X31S, His & Myc)

Griffithsin

Griffithsia Baculovirus Insect Cells
Mixed specificity lectin with anti-HIV activity. Binds to HIV envelope glycoproteins, including exterior membrane glycoprotein gp120, and inhibits viral entry into cells. Binding to gp120 is dependent on gp120 being glycosylated, and is inhibited by mannose, glucose and N-acetylglucosamine.
TMPK-01231 CLEC2D Protein, Human, Recombinant (hFc & Avi), Biotinylated

OCILmember D,LLT1,CLAX,CLEC2D,CLAXLLT-1,LLT-1,OCIL

Human HEK293 Cells
C-type lectin domain family 2, member D (CLEC2D) is implicated in the immune response. Pre-eclampsia and HIV infection have opposing immune responses. The contrasting expression of CLEC2D in HIV infection and pre-eclampsia is demonstrative of the immunosuppressive and pro-inflammatory roles of the respective pathologies.
TMPK-01230 CLEC2D Protein, Human, Recombinant (hFc & Avi)

Lectin-like NK cell receptor,LLT-1,OCIL,LLT1,Lectin-like tra...

Human HEK293 Cells
C-type lectin domain family 2, member D (CLEC2D) is implicated in the immune response. Pre-eclampsia and HIV infection have opposing immune responses. The contrasting expression of CLEC2D in HIV infection and pre-eclampsia is demonstrative of the immunosuppressive and pro-inflammatory roles of the respective pathologies. However, this implication may be confounded by highly active anti-retroviral treatment (HAART).
TMPJ-00873 CCL3L1 Protein, Human, Recombinant (His)

CCL3L3,G0S19-2,CCL3L1,Tonsillar Lymphocyte LD78 β,PAT 464.2,...

Human HEK293 Cells
C-C Motif Chemokine 3-Like 1 (CCL3L1) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. CCL3L1 is a ligand for CCR1, CCR3 and CCR5. CCL3L1 binds to several chemokine receptors including chemokine binding protein 2 and chemokine (C-C motif) receptor 5 (CCR5). CCR5 is a co-receptor for HIV, and binding of this protein to CCR5 inhibits HIV entry. The processed form LD78-beta (3-70) shows a 20-fold to 30-fold higher chemotactic activity and is a very potent inhibitor o...
TMPJ-00048 CYPA Protein, Mouse, Recombinant

SP18,PPIA,PPIase A,Peptidyl-prolyl cis-trans isomerase A,CYP...

Mouse E. coli
Peptidyl-prolyl cis-trans isomerase A is a cytoplasm protein which belongs to the cyclophilin-type PPIase family and PPIase A subfamily. Cyclophilins(CyPs) are a family of proteins found in organisms ranging from prokaryotes to humans. These molecules exhibit peptidyl-prolyl isomerase activity, suggesting that they influence the conformation of proteins in cells. Cyclophilin A accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopep...
TMPH-02300 RAD23A Protein, Human, Recombinant (His)

UV excision repair protein RAD23 homolog A,RAD23A

Human E. coli
Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to 'Lys-48'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to 'Lys-63'-linked polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome.; Involved in nucleotide excision repair and is thought to be functional equivalent for RAD23B in global genome nucle...
TMPH-01248 ADAR Protein, Human, Recombinant (His & SUMO)

ADAR1,IFI-4,136 kDa double-stranded RNA-binding protein,Inte...

Human E. coli
Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translation by changing codons and hence the amino acid sequence of proteins; pre-mRNA splicing by altering splice site recognition sequences; RNA stability by changing sequences involved in nuclease recognition; genetic stability in the case of RNA virus genomes by changing sequences duri...
TMPJ-01330 CD299 Protein, Human, Recombinant (His & Flag)

DC-SIGNR,L-SIGN,CD299,CD209L,LSIGN,C-type lectin domain fami...

Human HEK293 Cells
CD299 is also known as DC-SIGNR and CLEC4M, is a type II integral membrane protein. DC-SIGNR exists as a homotetramer, and the tandem repeat domain, also called neck domain, mediates oligermerization. Multiple human DC-SIGN/CD209 splice forms exist, generating both membrane-bound and soluble forms. DC-SIGNR is ragarded as a pathogen-recognition receptor involved in peripheral immune surveillance in liver, and probably mediate the endocytosis of pathogens which are subsequently degraded in lysoso...
TMPK-01316 CCR8 Protein, Cynomolgus, Recombinant (mFc)

GPR-CY6,CY6,CKRL1,CDw198,CMKBR8,ChemR1,CKR-L1,CD198,CCR-8,TE...

Cynomolgus HEK293 Cells
CC chemokine receptor (CCR) 8 (previously called CKR-L1 or TER1 and designated CD198), which is expressed on Th2 cells and eosinophils, has been implicated in allergic diseases. CCR8 may regulate monocyte chemotaxis and thymic cell line apoptosis and is alternative coreceptor with CD4 for HIV-1 infection. CCR8 Protein, Cynomolgus, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 29.73 kDa and the accession number is A0A8J8XUI3.
TMPK-00897 CCR8 Protein, Human, Recombinant (mFc)

GPR-CY6,CY6,CKRL1,CMKBRL2,TER-1,CDw198,CCR-8,CCR8,CKR-L1,CD1...

Human HEK293 Cells
CC chemokine receptor (CCR) 8 (previously called CKR-L1 or TER1 and designated CD198), which is expressed on Th2 cells and eosinophils, has been implicated in allergic diseases. CCR8 may regulate monocyte chemotaxis and thymic cell line apoptosis and is alternative coreceptor with CD4 for HIV-1 infection. CCR8 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 30.25 kDa and the accession number is P51685-1.
TMPK-00896 CCR8 Protein, Human, Recombinant (hFc)

GPR-CY6,CKR-L1,CMKBRL2,ChemR1,CDw198,CCR-8,CY6,TER-1,CCR8,CM...

Human HEK293 Cells
CC chemokine receptor (CCR) 8 (previously called CKR-L1 or TER1 and designated CD198), which is expressed on Th2 cells and eosinophils, has been implicated in allergic diseases. CCR8 may regulate monocyte chemotaxis and thymic cell line apoptosis and is alternative coreceptor with CD4 for HIV-1 infection. CCR8 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 30.62 kDa and the accession number is P51685-1.
TMPH-01064 CCR4 Protein, Human, Recombinant (His & SUMO)

CMKBR4,CD194,K5-5,CCR-4,C-C chemokine receptor type 4,CC-CKR...

Human E. coli
High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival. CCR4 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expressio...
TMPY-03285 PPIL1 Protein, Human, Recombinant (His)

CGI-124,PPIase,CYPL1,hCyPX,peptidylprolyl isomerase (cycloph...

Human E. coli
PPIL1 is a member of the cyclophilin family. Cyclophilins are well conserved and ubiquitous. Members of cyclophilin family take a significant part in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. PPIL1 is a peptidylprolyl isomerase(PPIase). It increases the folding of proteins and catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIL1 is involved in proliferation of cancer cells through modulation of phosphorylation of...
TMPH-01065 CCR4 Protein-VLP, Human, Recombinant (His)

CC-CKR-4,CCR4,CCR-4,CD194,C-C chemokine receptor type 4,K5-5...

Human HEK293 Cells
High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival. CCR4 Protein-VLP, Human, Recombinant (His) is expressed in HEK293 mammalian cel...
TMPY-03413 PPIL2 Protein, Human, Recombinant (aa 280-457, His)

UBOX7,Cyp-60,CYP60,CYC4,peptidylprolyl isomerase (cyclophili...

Human E. coli
PPIL2, is an enzyme that belongs to the cyclophilin family. The cyclophilins are peptidylprolyl isomerases and are highly conserved ubiquitous. They play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. PPIL2 interacts with the proteinase inhibitor eglin c and is localized in the nucleus. It contains 1 PPIL2 cyclophilin-type domain and 1 U-box domain. PPIL2 accelerate the folding of proteins. It catalyzes the cis-trans isomerization of pro...
TMPJ-01037 CXCR4 Protein, Human, Recombinant (hFc)

CXCR4,CD184,Fusin,D2S201E,FB22,HM89,HSY3RR,LAP3,LCR1,LESTR,N...

Human HEK293 Cells
C-X-C chemokine receptor type 4 (CXCR4) is an alpha-chemokine receptor specific for stromal-derived-factor-1 (SDF-1 also called CXCL12), a molecule endowed with potent chemotactic activity for lymphocytes. This receptor is one of several chemokine receptors that HIV isolates can use to infect CD4+ T cells. CXCR4 stands out for its pleiotropic roles in both physiological and pathological conditions and it represents a crucial target in drug development. CXCL12 is the principal CXCR4 specific liga...
TMPK-00668 IL-21R Protein, Cynomolgus, Recombinant (aa 41-254, His)

NILR,IL-21 receptor,IL-21R,CD360

Cynomolgus HEK293 Cells
IL-21 and IL-21R were highly expressed in the lesional skin and peripheral blood of psoriasis patients. IL-21 promoted CD4 T cells proliferation and Th17 cells differentiation and inhibiting Treg cells differentiation by upregulating RORγt expression and downregulating Foxp3 expression, with increased expression and secretion of IL-17A and IL-22.Microbial translocation and the associated immune activation during HIV-1 infection may lead to high expression levels of the IL-21R activation marker i...
TMPJ-00810 ITGA5 Protein, Human, Recombinant (His)

FNRA,Integrin α-5,Integrin Alpha-F,Fibronectin Receptor Subu...

Human HEK293 Cells
Integrin α-5 belongs to the Integrin α chain family and contains 7 FG-GAP repeats. Integrin α-5 joins with Integrin-β1 to form a fibronectin and laminin receptor which recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. It is expressed on fibroblasts, endothelial cells, peripheral T cells and platelets. Integrin α-5 undergoes post-translational cleavage in the ext...
TMPJ-00679 SGTA Protein, Human, Recombinant (His)

α-SGT,Alpha-SGT,SGT,Small Glutamine-Rich Tetratricopeptide R...

Human E. coli
Small Glutamine-Rich Tetratricopeptide Repeat-Containing Protein α (SGTA) is an ubiquitously expressed protein which belongs to the SGT Family. SGTA contains three TPR Protein-Protein Interaction Duplicates. SGTA is a co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity. SGTA is capable of interacting with the major nonstructural protein of Parvovirus H-1 and 70-kDa heat shock cognate protein. It interacts with NS1 from Parvovirus H-1, with Vpu and Gag from HIV...
TMPJ-00394 LDLR Protein, Human, Recombinant (Avi & His), Biotinylated

Low-Density Lipoprotein Receptor,LDL Receptor,LDLR

Human HEK293 Cells
Low-density lipoprotein receptor 9 (LDL receptor) is a single-pass type I membrane protein which belongs to the LDLR family. It contains 3 EGF-like domains, 7 LDL-receptor class A domains, and 6 LDL-receptor class B repeats. This protein binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. In case of HIV-1 infection, it functions as a r...
TMPJ-00621 LILRB1/CD85j/ILT2 Protein, Rhesus macaque, Recombinant (aa 17-456, His)

CD85j,ILT2,LILRB1

Rhesus HEK293 Cells
LILRB1, also known as CD85j and ILT2, is a transmembrane glycoprotein in the LILR immunoregulatory protein family. LILRB1 is expressed on NK cells that have expanded in response to acute HCMV infection. LILRB1 exhibits considerable diversity in the population, and polymorphisms in the LILRB1 gene have been associated with susceptibility to rheumatoid arthritis and weakly associated with HCMV disease in a subset of patients with HIV. The regulation of phagocytosis by macrophages is an additional ...
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重组蛋白

HIV-1 (group M, subtype CRF07_BC) gp140 Protein (His)
Cat.No: TMPY-02882
Species: HIV
Expression System: HEK293 Cells
HIV-1 (group M, subtype CRF07_BC) gp120 Protein (His)
Cat.No: TMPY-01373
Species: HIV
Expression System: HEK293 Cells
HIV-1 (group M, subtype B, strain 92418) p24 Protein (His)
Cat.No: TMPY-01552
Species: HIV
Expression System: E. coli
HIV-1 (group M, subtype B, strain HXB2) p24 Protein (His)
Cat.No: TMPY-04192
Species: HIV
Expression System: E. coli
HIV-1 gp120 Protein (His)
Cat.No: TMPJ-01313
Species: HIV
Expression System: HEK293 Cells
HIV-2 (subtype A, isolate ROD) Protein Vpx (His)
Cat.No: TMPH-01522
Species: HIV-2
Expression System: P. pastoris (Yeast)
HIV-2 (subtype A, isolate BEN) Protein Vpx (His)
Cat.No: TMPH-01521
Species: HIV-2
Expression System: E. coli
HIV-1 (group P, strain RBF168) gp140 Protein (hFc)
Cat.No: TMPY-00426
Species: HIV
Expression System: HEK293 Cells
HIV-1 (group O, strain BCF06) p24 Protein (His)
Cat.No: TMPY-04198
Species: HIV
Expression System: E. coli
HIV-1 (group P, strain RBF168) gp120 Protein (His)
Cat.No: TMPY-00427
Species: HIV
Expression System: HEK293 Cells
HIV-1 (group M, subtype CRF07_BC) gp140 Protein (hFc)
Cat.No: TMPY-01408
Species: HIV
Expression System: HEK293 Cells
HIV-1 (group M, subtype D, strain NDK) p24 Protein (His)
Cat.No: TMPY-04196
Species: HIV
Expression System: E. coli
HIV-1 (group M, subtype B, Isolate MN) gp120 Protein (His)
Cat.No: TMPY-04915
Species: HIV
Expression System: HEK293 Cells
HIV-1 (group M, subtype B, isolate BAL) gp120 Protein (His)
Cat.No: TMPY-00316
Species: HIV
Expression System: HEK293 Cells
HIV-1 (group M, subtype CRF07_BC) gp120 Protein (His), Biotinylated
Cat.No: TMPY-06486
Species: HIV
Expression System: HEK293 Cells
HIV-1 (group N, strain 06CM-U14296) p24 protein (His)
Cat.No: TMPY-01556
Species: HIV
Expression System: E. coli
HIV-2 (subtype CRF01_AB, strain 07JP_NMC716_clone_01) gp36 Protein (His & MBP)
Cat.No: TMPY-04061
Species: HIV
Expression System: E. coli
HIV-1 (group M, subtype A, strain 92UG037.1) gp140 Protein (hFc)
Cat.No: TMPY-00425
Species: HIV
Expression System: HEK293 Cells
HIV-1 (group M, subtype C, strain 92BR025) gp140 Protein (Fc)
Cat.No: TMPY-04871
Species: HIV
Expression System: HEK293 Cells
HIV-1 (group M, subtype C, strain 92BR025) p24 Protein (His)
Cat.No: TMPY-04194
Species: HIV
Expression System: E. coli
HIV-1 (group M, subtype C, isolate 92BR025) Protein Vpr (His & Myc)
Cat.No: TMPH-01519
Species: HIV-1
Expression System: E. coli
HIV-1 (group M, subtype B, strain SHIV-89.6P) gp120 Protein (His)
Cat.No: TMPY-00309
Species: HIV
Expression System: HEK293 Cells
HIV-1 (group N, strain 06CM-U14296) gp160 (gp120 subunit) Protein (His)
Cat.No: TMPY-01558
Species: HIV
Expression System: HEK293 Cells
HIV-1 (group M, subtype K, isolate 96CM-MP535) Protein Vpr (His & Myc)
Cat.No: TMPH-01520
Species: HIV-1
Expression System: E. coli
HIV-1 (group M, subtype A, isolate 92RW020) gp160 (gp120 subunit) Protein (His)
Cat.No: TMPY-00302
Species: HIV
Expression System: HEK293 Cells
HIV-p51/RT-p51 (group M, subtype B (isolate HXB2) Gag-Pol polyprotein Protein (His)
Cat.No: TMPY-04150
Species: HIV
Expression System: E. coli
HIV-p66/RT-p66 (group M, subtype B (isolate HXB2) Gag-Pol polyprotein Protein (His)
Cat.No: TMPY-04161
Species: HIV
Expression System: E. coli
DMBT1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01442
Species: Human
Expression System: HEK293 Cells
Griffithsin Protein, Griffithsia sp., Recombinant (X31S, His)
Cat.No: TMPH-00777
Species: Griffithsia
Expression System: E. coli
Griffithsin Protein, Griffithsia sp., Recombinant (X31S, His & Myc)
Cat.No: TMPH-00776
Species: Griffithsia
Expression System: Baculovirus Insect Cells
CLEC2D Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPK-01231
Species: Human
Expression System: HEK293 Cells
CLEC2D Protein, Human, Recombinant (hFc & Avi)
Cat.No: TMPK-01230
Species: Human
Expression System: HEK293 Cells
CCL3L1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00873
Species: Human
Expression System: HEK293 Cells
CYPA Protein, Mouse, Recombinant
Cat.No: TMPJ-00048
Species: Mouse
Expression System: E. coli
RAD23A Protein, Human, Recombinant (His)
Cat.No: TMPH-02300
Species: Human
Expression System: E. coli
ADAR Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01248
Species: Human
Expression System: E. coli
CD299 Protein, Human, Recombinant (His & Flag)
Cat.No: TMPJ-01330
Species: Human
Expression System: HEK293 Cells
CCR8 Protein, Cynomolgus, Recombinant (mFc)
Cat.No: TMPK-01316
Species: Cynomolgus
Expression System: HEK293 Cells
CCR8 Protein, Human, Recombinant (mFc)
Cat.No: TMPK-00897
Species: Human
Expression System: HEK293 Cells
CCR8 Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00896
Species: Human
Expression System: HEK293 Cells
CCR4 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01064
Species: Human
Expression System: E. coli
PPIL1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03285
Species: Human
Expression System: E. coli
CCR4 Protein-VLP, Human, Recombinant (His)
Cat.No: TMPH-01065
Species: Human
Expression System: HEK293 Cells
PPIL2 Protein, Human, Recombinant (aa 280-457, His)
Cat.No: TMPY-03413
Species: Human
Expression System: E. coli
CXCR4 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-01037
Species: Human
Expression System: HEK293 Cells
IL-21R Protein, Cynomolgus, Recombinant (aa 41-254, His)
Cat.No: TMPK-00668
Species: Cynomolgus
Expression System: HEK293 Cells
ITGA5 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00810
Species: Human
Expression System: HEK293 Cells
SGTA Protein, Human, Recombinant (His)
Cat.No: TMPJ-00679
Species: Human
Expression System: E. coli
LDLR Protein, Human, Recombinant (Avi & His), Biotinylated
Cat.No: TMPJ-00394
Species: Human
Expression System: HEK293 Cells
LILRB1/CD85j/ILT2 Protein, Rhesus macaque, Recombinant (aa 17-456, His)
Cat.No: TMPJ-00621
Species: Rhesus
Expression System: HEK293 Cells
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Cat. No. Product Name Target Signaling Pathways
TMIJ-0076 Ritonavir-13C-d3

Ritonavir-13C-d3 是 Ritonavir 的 13C 和氘代化合物。Ritonavir 的 CAS 号为 155213-67-5。Ritonavir 是一种 HIV 蛋白酶抑制剂,可研究 HIV 感染和 AIDS 。它也是SARS-CoV 3CLpro的抑制剂,IC50为 1.61 μM。
T27097 CTP518

CTP 518,Deuterated Atazanivir-D3-1,CTP-518

CTP518, a deuterated Atazanivir derivative, is a HIV protease inhibitor.
TMID-0082 Lopinavir-d8

Lopinavir-d8 是 Lopinavir 的氘代化合物。Lopinavir 的 CAS 号为 192725-17-0。Lopinavir 是一种选择性肽模拟 HIV-1 蛋白酶的高效抑制剂。它通过阻止 HIV-1 的成熟而起作用,从而阻断其感染性。它也是SARS-CoV 3CLpro的抑制剂。
TMIJ-0239 Cobicistat-d8

Cobicistat-d8 是 Cobicistat 的氘代化合物。Cobicistat 的 CAS 号为 1004316-88-4。Cobicistat 是一种细胞色素酶P450 3A 的选择性抑制剂,IC50值为30-285 nM。它是一种药代动力学增强剂,可增强抗 HIV 药物的吸收。
T11814 Lamivudine 13C,15N2

Others Others
Lamivudine 13C,15N2, an impurity of Lamivudine (BCH-189), functions as an inhibitor of both HIV-1/2 reverse transcriptase and hepatitis B virus reverse transcriptase, classifying it as a nucleoside reverse transcriptase inhibitor (NRTIs).
TMID-0206 Nevirapine-d3

Nevirapine-d3 是 Nevirapine 的氘代化合物。Nevirapine 的 CAS 号为 129618-40-2。Nevirapine 是一种HIV-1逆转录酶非核苷抑制剂,Ki值为 270 μM,可用于研究 HIV/AIDS。
TMID-0266 Stavudine-α,α,α,6-d4

Stavudine-α,α,α,6-d4 是 Stavudine 的氘代化合物。Stavudine 的 CAS 号为 3056-17-5。Stavudine 是一种口服活性核苷逆转录酶抑制剂,还抑制线粒体 DNA 的复制,具有抗HIV-1和HIV-2的活性。它降低 NLRP3 炎症小体激活,调节淀粉样 β 自噬,诱导细胞凋亡。
T11247 Etravirine D4

R-165335 D4,TMC-125 D4,依曲韦林 D4

Others Others
Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV. Etravirine D4 is the deuterium labeled Etravirine.
TMID-0205 Nevirapine-d4

Nevirapine-d4 是 Nevirapine 的氘代化合物。Nevirapine 的 CAS 号为 129618-40-2。Nevirapine 是一种HIV-1逆转录酶非核苷抑制剂,Ki值为 270 μM,可用于研究 HIV/AIDS。
TMID-0285 Lamivudine-13C-d2

Lamivudine-13C-d2 是 Lamivudine 的 13C 和氘代化合物。Lamivudine 的 CAS 号为 134678-17-4。Lamivudine 是一种核苷逆转录酶抑制剂,可抑制HIV逆转录酶1和2 以及乙型肝炎病毒的逆转录酶。
TMIJ-0217 Abacavir-d4

Abacavir-d4 是 Abacavir 的氘代化合物。Abacavir 的 CAS 号为 136470-78-5。Abacavir是一种核苷类似物逆转录酶抑制剂。
TMIJ-0029 Sulfadoxine-d4

Sulfadoxine-d4 是 Sulfadoxine 的氘代化合物。Sulfadoxine 的 CAS 号为 2447-57-6。Sulfadoxine是磺胺类化合物,常与pyrimethamine结合起到抗疟疾作用。它抑制HIV在外周血单核细胞中的复制。
TMIJ-0279 Sulfadoxine-d3

Sulfadoxine-d3 是 Sulfadoxine 的氘代化合物。Sulfadoxine 的 CAS 号为 2447-57-6。Sulfadoxine是磺胺类化合物,常与pyrimethamine结合起到抗疟疾作用。它抑制HIV在外周血单核细胞中的复制。
TMIJ-0109 Erythromycin Ethylsuccinate-13C-d3

Erythromycin Ethylsuccinate-13C-d3 是 Erythromycin Ethylsuccinate 的 13C 和氘代化合物。Erythromycin Ethylsuccinate 的 CAS 号为 1264-62-6。Erythromycin Ethylsuccinate是一种由红链霉菌产生的大环内酯类抗生素,有潜力用于多种细菌感染。它具有抗HIV-1病毒活性。

同位素标记化合物

Ritonavir-13C-d3
Cat.No: TMIJ-0076
Synonym:
Target:
CTP518
Cat.No: T27097
Synonym: CTP 518,Deuterated Atazanivir-D3-1,CTP-518
Target:
Lopinavir-d8
Cat.No: TMID-0082
Synonym:
Target:
Cobicistat-d8
Cat.No: TMIJ-0239
Synonym:
Target:
Lamivudine 13C,15N2
Cat.No: T11814
Synonym:
Target: Others
Nevirapine-d3
Cat.No: TMID-0206
Synonym:
Target:
Stavudine-α,α,α,6-d4
Cat.No: TMID-0266
Synonym:
Target:
Etravirine D4
Cat.No: T11247
Synonym: R-165335 D4,TMC-125 D4,依曲韦林 D4
Target: Others
Nevirapine-d4
Cat.No: TMID-0205
Synonym:
Target:
Lamivudine-13C-d2
Cat.No: TMID-0285
Synonym:
Target:
Abacavir-d4
Cat.No: TMIJ-0217
Synonym:
Target:
Sulfadoxine-d4
Cat.No: TMIJ-0029
Synonym:
Target:
Sulfadoxine-d3
Cat.No: TMIJ-0279
Synonym:
Target:
Erythromycin Ethylsuccinate-13C-d3
Cat.No: TMIJ-0109
Synonym:
Target:
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