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Search Results for " hif-1α inhibitor-1 "
Targets Recommended: Others

28

抑制剂 & 化合物

1

天然产物

1732

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T71661 HIF-1α inhibitor-1

Others Others
HIF-1α inhibitor-1 is a HIF-1 alpha inhibitor.
T71659 Indacaterol acetate

Others Others
Indacaterol acetate is an ultra-long-acting beta-adrenoceptor agonist.
T36290 HIF-1 inhibitor-1

Others Others
HIF-1 inhibitor-1 is an aryl carboxamide compound and a potent hypoxia-inducible factor 1 (HIF-1) inhibitor with an IC50 of 0.32 μM for the cancer metastasi[1]. [1]. Liu M, et al. Discovery of Novel Aryl Carboxamide Derivatives as Hypoxia-Inducible Factor 1α Signaling Inhibitors with Potent Activities of Anticancer Metastasis. J Med Chem. 2019 Oct 24;62(20):9299-9314.
T3494 LW6

HIF-1α inhibitor,CAY10585,LW8

Apoptosis; Dehydrogenase; HIF/HIF Prolyl-Hydroxylase; HIF Angiogenesis; Apoptosis; Chromatin/Epigenetic; Metabolism
LW6 (HIF-1α inhibitor) 是一种新型 HIF-1抑制剂,IC50值为 4.4 μM。它降低 HIF-1α蛋白表达,但不影响 HIF-1β 表达。
T67767 HIF-1 inhibitor-4

HIF-1 inhibitor-4

HIF Angiogenesis; Chromatin/Epigenetic
HIF-1 inhibitor-4 (HIF-1 inhibitor-4) 是一种 HIF-1 抑制剂 (IC50: 560 nM)。HIF-1 inhibitor-4 减少 HIF-1α 蛋白水平,但不影响 mRNA 水平。
T15396 GN44028

N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,4-dihydroindeno[1,2-c]pyrazol-3-amine

HIF Angiogenesis; Chromatin/Epigenetic
GN44028 (N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,4-dihydroindeno[1,2-c]pyrazol-3-amine) 是缺氧诱导因子(HIF)-1的有效抑制剂,其 IC50=14 nM。它可以抑制低氧诱导的 HIF-1α 的转录特性,但不抑制 HIF-1α mRNA 的表达,HIF-1α 蛋白的累积或HIF-1α/HIF-1β 的异缘二聚化。
T60413 HIF-IN-1

HIF Angiogenesis; Chromatin/Epigenetic
HIF-IN-1 是一种有效的缺氧诱导因子 (HIF-1) 抑制剂,与肿瘤和癌细胞的增殖有关,对 HIF-1α 蛋白聚集有抑制作用。
T4381 Lificiguat

利非西呱,YC-1

Others; Guanylate cyclase; HIF Angiogenesis; Chromatin/Epigenetic; GPCR/G Protein; Others
Lificiguat (YC-1) 是一种不依赖一氧化氮的可溶性鸟苷酸环化酶激活剂和低氧诱导因子 1α 的抑制剂。
T2283 PX-12

2-[(1-甲基丙基)二硫代]-1H-咪唑,IV-2,PX12

Thioredoxin Metabolism
PX-12 (PX12) 是一种可逆的硫氧还蛋白-1(Trx-1)抑制剂,能够抑制 MCF-7 细胞(IC50:1.9 μM)和HT-29 细胞(IC50:2.9 μM)的生长。
T82595 DEALA-Hyp-YIPD

DEALA-Hyp-YIPD为HIF-1α抑制剂,阻断VHL/HIF-1α相互作用,显示IC50值为0.91 μM,Kd为180 nM。
T61161 HIF-1α-IN-3

Others Others
HIF-1α-IN-3, also known as Compound (S)-3f, is a hypoxia-selective inhibitor of HIF-1α. It exhibits potent antiestrogenic activity [1].
T82198 HIF-1α-IN-6

HIF/HIF Prolyl-Hydroxylase Chromatin/Epigenetic; Metabolism
HIF-1α-IN-6 (compound 3s) 为HIF-1α抑制剂,MiaPaCa-2 和 MDA-MB-231 细胞中IC50分别为 0.6 nM 和 53.3 nM。它通过减少HIF-1α mRNA水平来抑制HIF-1α表达。
T60398 Dimethyl-bisphenol A

Others Others
Dimethyl-bisphenol A (DMBPA) 是有效的HIF-1α抑制剂,通过从 HIF-1α 解离 Hsp90 促进 HIF-1α 蛋白的降解。Dimethyl-bisphenol A 可降低 Vegfa mRNA 的表达。
T6804 Chetomin

Chaetomin,NSC289491,BRN0077366

Apoptosis; HSP; HIF Angiogenesis; Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; Metabolism
Chetomin (BRN0077366) 是球毛壳菌的活性成分,是一种无毒的非小细胞肺癌干细胞靶向分子。它是一种热休克蛋白90/缺氧诱导因子1α 途径的抑制剂。
T27866 LXY6090

LXY 6090,LXY-6090

Others Others
LXY6090 is a HIF-1 inhibitor. LXY6090 inhibited the activity of HIF-1 and downregulated the protein level of HIF-1α in breast cancer cells. LXY6090 showed in vivo anticancer efficacy by decreasing the HIF-1α expression in nude mice bearing MX-1 tumor xeno
T60524 HIF-1α-IN-4

Others Others
HIF-1α-IN-4 是 HIF-1α抑制剂,在 HEK293T 细胞中的IC50值为 24 nM,具有潜在的抗肿瘤作用。 HIF-1α-IN-4 在缺氧条件下下调 VEGF 和 PDK1 mRNA 的表达。
T60532 HIF-1α-IN-5

Others Others
HIF-1α-IN-5 是 HIF-1α的抑制剂,在 HEK293T 细胞中的 IC50值为 24 nM,也可抑制 MAO-A 的活性。 在缺氧条件下, HIF-1α-IN-5可下调 VEGF 和 PDK1 mRNA 的表达。HIF-1α-IN-5 具有用于癌症研究的潜力。
T78123 HIF-1α-IN-2 hydrochloride

HIF/HIF Prolyl-Hydroxylase Chromatin/Epigenetic; Metabolism
HIF-1α-IN-2 hydrochloride 是一款有效的 HIF-1α 抑制剂,对抗癌活性显著,其在MDA-MB-231细胞和MiaPaCa-2细胞中的IC50值分别为28 nM和15 nM。该化合物主要通过抑制转录和阻碍蛋白质合成来下调HIF-1α的表达。
T74530 GEM-5

Others Others
GEM-5为基于吉西他滨且含HIF-1α抑制剂(YC-1)的偶联物,IC50值为30 nM。此化合物能有效降低HIF-1α表达,并提高肿瘤抑制因子p53的表达量。GEM-5可诱导A2780细胞的凋亡(apoptosis),进而抑制肿瘤生长。
T61442 HIF-1/2α-IN-1

Others Others
HIF-1/2α-IN-1, an orally active compound, functions as an inhibitor of HIF-2α. Its inhibitory effect on HIF-2α activity is significant, with an IC 50 value of 0.92 μM. Furthermore, HIF-1/2α-IN-1 has the ability to decrease HIF-1α levels. This compound is particularly valuable for research on clear cell renal cell carcinoma (ccRCC) [1].
TP2046L TAT-cyclo-CLLFVY acetate(1446322-66-2 Free base)

TAT-cyclo-CLLFVY acetate(1446322-66-2 Free base) 是一种选择性 HIF-1 二聚化抑制剂。 TAT-cyclo-CLLFVY acetate 阻断重组 HIF-1αHIF-1β 的蛋白质-蛋白质相互作用,但不阻断 HIF-2α 与 HIF-1β (IC50 = 1.3 μM)。 TAT-cyclo-CLLFVY acetate 在体外抑制缺氧诱导的 HIF-1 活性,并降低骨肉瘤和乳腺癌细胞中 VEGF 和 CAIX 的表达。 TAT-cyclo-CLLFVY acetate 减少缺氧 HUVEC 的管状化。
TP2046 TAT-cyclo-CLLFVY

Selective HIF-1 dimerization inhibitor. Blocks protein-protein interaction of recombinant HIF-1α, but not HIF-2α, with HIF-1β (IC50 = 1.3 μM). Inhibits hypoxia-induced HIF-1 activity, and decreases VEGF and CAIX expression in osteosarcoma and breast cance
T63035 Izilendustat hydrochloride

Others Others
Izilendustat (hydrochloride) 是一种脯氨酰羟化酶 (prolyl hydroxylase) 的有效抑制剂,能够稳定缺氧诱导因子-1 α (HIF-1α) 和缺氧诱导因子-2 (HIF-2)。Izilendustat (hydrochloride) 具有潜力进行 HIF-1α 相关疾病的研究(包括外周血管疾病(PVD)、心力衰竭、冠状动脉疾病(CAD)、缺血、贫血、结肠炎和其他炎症性肠病)。
T79720 VHL-IN-1

HIF/HIF Prolyl-Hydroxylase Chromatin/Epigenetic; Metabolism
VHL-IN-1 (compound 30) 为泛素 E3 连接酶 von Hippel-Lindau (VHL) 的抑制剂,其解离常数 Kd 为 37 nM,能够稳定并激活 HIF-1α 转录功能。此化合物具备作为 HIF-1α 稳定剂以及蛋白水解靶向嵌合体(PROTACs) 降解剂的应用潜力。
T75943 TAT-cyclo-CLLFVY TFA

TAT-cyclo-CLLFVY TFA 是一种 HIF-1异二聚化的环肽抑制剂,可抑制癌细胞中的缺氧信号传导。TAT-cyclo-CLLFVY TFA 破坏 HIF-1α/HIF-1β蛋白相互作用,IC50为 1.3 μM。
T60539 KG-548

Others Others
KG-548 是一种ARNT/TACC3干扰剂以及HIF-1α抑制剂。KG-548 通过 ARNT 的 PAS-B 结构域与 TACC3 竞争性结合,直接干扰ARNT/TACC3复合物的形成。ARNT 是芳基烃受体核转运蛋白,也称为 HIF-β。
T18667 (S,R,S)-AHPC-C5-COOH

VH032-C5-COOH

Others Others
(S,R,S)-AHPC-C5-COOH (VH032-C5-COOH) is a synthesized E3 ligase ligand-linker conjugate, contains the VH032 VHL-based ligand and a linker to form PROTACs. VH-032 is a selective and potent inhibitor of VHL/HIF-1α interaction with a Kd of 185 nM, has the potential for the study of anemia and ischemic diseases[1].
T84747 (R,S,S)-VH032

Others Others
(R,S,S)-VH032 为E3 Ligase用于PROTACs合成的Ligand。作为VHL配体及VHL/HIF-1α相互作用抑制剂,该化合物用于募集von Hippel-Lindau (VHL)蛋白,进而可合成针对tau的小分子PROTACC004019。

化合物

HIF-1α inhibitor-1
Cat.No: T71661
Synonym:
Target: Others
Indacaterol acetate
Cat.No: T71659
Synonym:
Target: Others
HIF-1 inhibitor-1
Cat.No: T36290
Synonym:
Target: Others
LW6
Cat.No: T3494
Synonym: HIF-1α inhibitor,CAY10585,LW8
Target: Apoptosis, Dehydrogenase, HIF/HIF Prolyl-Hydroxylase, HIF
HIF-1 inhibitor-4
Cat.No: T67767
Synonym: HIF-1 inhibitor-4
Target: HIF
GN44028
Cat.No: T15396
Synonym: N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,4-dihydroindeno[1,2-c]pyrazol-3-amine
Target: HIF
HIF-IN-1
Cat.No: T60413
Synonym:
Target: HIF
Lificiguat
Cat.No: T4381
Synonym: 利非西呱,YC-1
Target: Others, Guanylate cyclase, HIF
PX-12
Cat.No: T2283
Synonym: 2-[(1-甲基丙基)二硫代]-1H-咪唑,IV-2,PX12
Target: Thioredoxin
DEALA-Hyp-YIPD
Cat.No: T82595
Synonym:
Target:
HIF-1α-IN-3
Cat.No: T61161
Synonym:
Target: Others
HIF-1α-IN-6
Cat.No: T82198
Synonym:
Target: HIF/HIF Prolyl-Hydroxylase
Dimethyl-bisphenol A
Cat.No: T60398
Synonym:
Target: Others
Chetomin
Cat.No: T6804
Synonym: Chaetomin,NSC289491,BRN0077366
Target: Apoptosis, HSP, HIF
LXY6090
Cat.No: T27866
Synonym: LXY 6090,LXY-6090
Target: Others
HIF-1α-IN-4
Cat.No: T60524
Synonym:
Target: Others
HIF-1α-IN-5
Cat.No: T60532
Synonym:
Target: Others
HIF-1α-IN-2 hydrochloride
Cat.No: T78123
Synonym:
Target: HIF/HIF Prolyl-Hydroxylase
GEM-5
Cat.No: T74530
Synonym:
Target: Others
HIF-1/2α-IN-1
Cat.No: T61442
Synonym:
Target: Others
TAT-cyclo-CLLFVY acetate(1446322-66-2 Free base)
Cat.No: TP2046L
Synonym:
Target:
TAT-cyclo-CLLFVY
Cat.No: TP2046
Synonym:
Target:
Izilendustat hydrochloride
Cat.No: T63035
Synonym:
Target: Others
VHL-IN-1
Cat.No: T79720
Synonym:
Target: HIF/HIF Prolyl-Hydroxylase
TAT-cyclo-CLLFVY TFA
Cat.No: T75943
Synonym:
Target:
KG-548
Cat.No: T60539
Synonym:
Target: Others
(S,R,S)-AHPC-C5-COOH
Cat.No: T18667
Synonym: VH032-C5-COOH
Target: Others
(R,S,S)-VH032
Cat.No: T84747
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
T75487 7-Hydroxyneolamellarin A

Others Others
7-Hydroxyneolamellarin A,一种从海绵Dendrilla nigra 提取的天然产物,是高效的缺氧诱导因子 1α (HIF-1α) 抑制剂。该化合物能够减弱HIF-1α蛋白的积累,并抑制血管表皮生长因子 (VEGF) 的转录活性,因而在癌症研究中有应用价值。

天然产物

7-Hydroxyneolamellarin A
Cat.No: T75487
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPY-04451 AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)

AMPK, AMPK(α1, β1, γ1)

Human Baculovirus Insect Cells
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&Q13131-1.
TMPY-03878 Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)

Integrin alpha V β6,ITGAV & ITGB6,integrin, alpha 5 (fibrone...

Human HEK293 Cells
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1.
TMPY-02501 CD3D & CD3E Heterodimer Protein, Human, Recombinant

CD3d molecule, δ (CD3-TCR complex),CD3-δ,CD3d molecule, delt...

Human HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1.
TMPY-02030 CD82 Protein, Human, Recombinant (His)

CD82 molecule,SAR2,R2,KAI-1,4F9,KAI1,C33,T...

Human HEK293 Cells
CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signalling. Downregulation of CD82 expression is associated with the advanced stages of many human cancers and correlates with the acquisition of metastatic potential. Recent stud...
TMPY-01894 SIGIRR Protein, Human, Recombinant (His)

TIR8,single immunoglobulin and toll-interleukin 1 r...

Human HEK293 Cells
SIGIRR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14 kDa and the accession number is Q6IA17-1.
TMPY-01247 FLT3 Protein, Human, Recombinant (T227M, His)

FLK2,FLK-2,CD135,STK1,fms-related tyrosine...

Human HEK293 Cells
FLT3 Protein, Human, Recombinant (T227M, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.7 kDa and the accession number is P36888-1.
TMPY-02779 Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)

thyroid peroxidase,MSA,TPX,TDH2A

Human Baculovirus Insect Cells
Thyroid peroxidase is a membrane-bound glycoprotein which belongs to the peroxidase family, XPO subfamily. It contains 1 EGF-like domain and 1 Sushi (CCP/SCR) domain. Thyroid Peroxidase represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. It used to be taken as the formerly so-called `microsomal antigen` several years ago. As an integral membrane glycoprotein it is restricted to the apical plasma membrane of the follicular epithelial cells and comprises two i...
TMPY-03290 HGF Protein, Mouse, Recombinant

hepatocyte growth factor (hepapoietin A,NK1,scatter...

Mouse HEK293 Cells
HGF Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 79.3 kDa and the accession number is Q08048-1.
TMPY-04970 TIGIT Protein, Human, Recombinant (hFc)

WUCAM,VSTM3,VSIG9,T cell immunoreceptor with Ig and ITIM dom...

Human HEK293 Cells
TIGIT Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.2 kDa and the accession number is Q495A1-1.
TMPY-01147 R-Spondin 1/RSPO1 Protein, Human, Recombinant (His)

RSPO,CRISTIN3,R-spondin 1

Human HEK293 Cells
R-Spondin 1/RSPO1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.2 kDa and the accession number is Q2MKA7-1.
TMPY-04346 PD-L2 Protein, Human, Recombinant (His)

PD-L2,B7-DC,CD273,Btdc,PDCD1L2,B7DC,PDL2,programmed...

Human HEK293 Cells
PD-L2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9BQ51-1.
TMPY-00947 VCAM-1 Protein, Human, Recombinant (hFc)

INCAM-100,CD106,VCAM-1,vascular c...

Human HEK293 Cells
VCAM-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 100.8 kDa and the accession number is P19320-1.
TMPY-01949 CD19 Protein, Human, Recombinant (His)

CD19 molecule,B4,CVID3

Human HEK293 Cells
CD19 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.6 kDa and the accession number is P15391-1.
TMPY-04165 FGFR3 Protein, Human, Recombinant (His)

JTK4,CEK2,fibroblast growth factor receptor 3,HSFGFR3EX,CD33...

Human HEK293 Cells
FGFR3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.6 kDa and the accession number is P22607-1.
TMPY-00820 IgG1 Fc Protein, Human, Recombinant (C103S)

Ighg1,IgG1 Fc

Human HEK293 Cells
IgG1 Fc Protein, Human, Recombinant (C103S) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26 kDa and the accession number is P01857-1.
TMPY-01146 Insulin Receptor Protein, Human, Recombinant (long isoform, His)

HHF5,CD220,insulin receptor

Human HEK293 Cells
Insulin Receptor Protein, Human, Recombinant (long isoform, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 107 kDa and the accession number is P06213-1.
TMPY-04348 CTLA-4 Protein, Human, Recombinant (His)

ALPS5,CD152,GRD4,cytotoxic T-lymphocyte-associated ...

Human HEK293 Cells
CTLA-4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15 kDa and the accession number is P16410-1.
TMPY-02813 ErbB4 Protein, Human, Rhesus, Recombinant (His)

erb-b2 receptor tyrosine kinase 4

Human,Rhesus HEK293 Cells
ErbB4 Protein, Human, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.1 kDa and the accession number is Q15303-1.
TMPY-05220 TSLP Protein, Human, Recombinant (R127A & R130S, His)

thymic stromal lymphopoietin

Human HEK293 Cells
TSLP Protein, Human, Recombinant (R127A & R130S, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.2 kDa and the accession number is Q969D9-1.
TMPY-01827 CD30/TNFRSF8 Protein, Human, Recombinant (His)

D1S166E,tumor necrosis factor receptor sup...

Human HEK293 Cells
CD30/TNFRSF8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P28908-1.
TMPY-00853 IL-1RA Protein, Human, Recombinant

DIRA,IL1RA,interleukin 1 receptor antagoni...

Human E. coli
IL-1RA Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.3 kDa and the accession number is P18510-1.
TMPY-01850 CEACAM3 Protein, Human, Recombinant (His)

W282,W264,CEA,CD66D,CGM1,MGC11987...

Human HEK293 Cells
CeACAM3 (CD66d), a member of carcinoembryonic antigen family, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. There are four members in this family: CD66a, CD66b, CD66c, and CD66d. Members of CEACAM family are widely expressed especially on human neutrophils, and, depending on the tissue, capable of regulating diverse functions including tumor promotion, tumor suppression, angiogenesis, and neutrophil activation. Abnormal overexp...
TMPY-02245 SNAP-25 Protein, Human, Recombinant (His)

synaptosomal-associated protein, 25kDa,SEC9,SNAP,RIC-4,dJ

Human E. coli
Synaptosomal-associated protein 25, also known as Super protein, Synaptosomal-associated 25 kDa protein, SNAP25 and SNAP, is a cytoplasm and cell membrane protein that belongs to the SNAP-25 family. SNAP25 / SUP contains 2 t-SNARE coiled-coil homology domains. SNAP25 / SUP is a membrane bound protein anchored to the cytosolic face of membranes via palmitoyl side chains in the middle of the molecule. SNAP25 / SUP protein is a component of the SNARE complex, which is proposed to account for the sp...
TMPY-00203 LOXL2 Protein, Mouse, Recombinant (His)

1110004B06Rik,4930526G1<...

Mouse HEK293 Cells
Lysyl oxidase homolog 2, also known as Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, Lysyl oxidase-related protein WS9-14 and LOXL2, is a secreted protein that belongs to the lysyl oxidase family. LOXL2 contains four SRCR domains. The lysyl oxidase family is made up of five members: lysyl oxidase (LOX) and lysyl oxidase-like 1-4 ( LOXL1, LOXL2, LOXL3, LOXL4 ). All members share conserved C-terminal catalytic domains that provide for lysyl oxidase or lysyl oxidase-like enzyme act...
TMPY-01281 ACVR2B Protein, Mouse, Recombinant (His)

ActRIIB,activin A receptor, type IIB,4930516B21...

Mouse HEK293 Cells
ACVR2B Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is P27040-1.
TMPY-01851 CD73 Protein, Human, Recombinant (His)

eN,NT5,E5NT,NT,5'-nucleotidase, ecto (CD73),NTE,CALJA,eNT,CD...

Human HEK293 Cells
CD73 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.2 kDa and the accession number is P21589-1.
TMPY-02525 RGMA Protein, Human, Recombinant (His)

repulsive guidance molecule family member a,RGM

Human HEK293 Cells
RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that form...
TMPY-03967 BTN3A3 Protein, Human, Recombinant (His)

BTF3,BTN3.3,butyrophilin subfamily 3 member A3,BTN3A3

Human HEK293 Cells
BTN3A3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is O00478-1.
TMPY-05208 PD-L1 Protein, Human, Recombinant

CD274 molecule,PDCD1L1,PD-L1,PDL<...

Human HEK293 Cells
PD-L1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 25.2 kDa and the accession number is Q9NZQ7-1.
TMPY-00978 Progranulin Protein, Human, Recombinant (His)

PGRN,PCDGF,CLN11,Granulin,GP88,GEP,Granuli...

Human HEK293 Cells
Progranulin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 63.2 kDa and the accession number is P28799-1.
TMPY-03407 NQO1 Protein, Human, Recombinant (His)

NAD(P)H dehydrogenase, quinone 1,NMORI,DIA4,QR1...

Human E. coli
NQO1 gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. NQO1 forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one-electron reduction of quinones that results in the production of radical species. Mutations in the NQO1 gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered ex...
TMPY-01258 IL-13RA1 Protein, Human, Recombinant (His)

NR4,interleukin 13 receptor, alpha 1,CD2

Human HEK293 Cells
IL-13RA1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.3 kDa and the accession number is P78552-1.
TMPY-03531 PSGL-1/CD162 Protein, Human, Recombinant (His)

selectin P ligand,PSGL-1,PSGL1,CD1

Human HEK293 Cells
PSGL-1/CD162 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.5 kDa and the accession number is Q14242-1.
TMPY-01883 EPOR Protein, Human, Recombinant (His)

erythropoietin receptor,EPO-R

Human HEK293 Cells
EPOR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is P19235-1.
TMPY-01862 IL-4 Protein, Human, Recombinant

Interleukin-4,IL-4,BCGF1,白细胞介素,interleukin 4,BSF

Human E. coli
IL-4 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.1 kDa and the accession number is P05112-1.
TMPY-06418 R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc)

R-spondin 2,CRISTIN2

Human HEK293 Cells
R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.01 kDa and the accession number is Q6UXX9-1.
TMPY-04333 LRRC15 Protein, Human, Recombinant (hFc)

leucine rich repeat containing 15,LIB

Human HEK293 Cells
LRRC15 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 84.5 kDa and the accession number is Q8TF66-1.
TMPY-02033 CD44 Protein, Human, Recombinant (His)

CD44 molecule (Indian blood group),IN,MC56,HUTCH-I,MIC4,CDW4...

Human HEK293 Cells
CD44 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.4 kDa and the accession number is P16070-1.
TMPY-04104 LIF Protein, Human, Recombinant

CDF,DIA,白血病抑制因子,MLPLI,Leukemia Inhibitory Factor,HI...

Human HEK293 Cells
LIF Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 19.7 kDa and the accession number is P15018-1.
TMPY-04939 LAG-3 Protein, Human, Recombinant

LAG-3,lymphocyte-activation gene 3,CD223

Human HEK293 Cells
LAG-3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 45.3 kDa and the accession number is P18627-1.
TMPY-00861 IL-33 Protein, Human, Recombinant

IL1F11,C9orf26,NFEHEV,NF-HEV,DVS2...

Human E. coli
IL-33 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18 kDa and the accession number is O95760-1.
TMPY-06873 FLT3 Ligand Protein, Human, Recombinant

FLT3LG,fms related tyrosine kinase 3 ligand,FLT3L,FL

Human E. coli
FLT3 Ligand Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.75 kDa and the accession number is P49771-1.
TMPY-01185 DR5/TRAIL R2 Protein, Human, Recombinant (His)

KILLER,TRICK2A,TRICK2,DR5,TRICKB,tumor necrosis factor recep...

Human HEK293 Cells
DR5/TRAIL R2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.7 kDa and the accession number is O14763-1.
TMPY-01938 CD98 Protein, Human, Recombinant (His)

4T2HC,4F2,CD98HC,NACAE,MDU1,4F2HC,CD98,solute carri...

Human HEK293 Cells
CD98 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.2 kDa and the accession number is P08195-1.
TMPY-01137 HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His)

erb-b2 receptor tyrosine kinase 2,NEU,ENVW,HERV-7q,HERV7Q,HE...

Human HEK293 Cells
HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71 kDa and the accession number is P04626-1.
TMPY-04826 LILRB5/CD85c Protein, Human, Recombinant (His)

leukocyte immunoglobulin like receptor B5,LIR8,LIR-8,CD85C

Human HEK293 Cells
A genetic variant in LILRB5 (leukocyte immunoglobulin-like receptor subfamily-B) (rs12975366: T > C: Asp247Gly) has been reported to be associated with lower creatine phosphokinase (CK) and lactate dehydrogenase (LDH) levels. Both biomarkers are released from injured muscle tissue, making this variant a potential candidate for susceptibility to muscle-related symptoms. LILRB5/CD85c Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weig...
TMPY-01744 ACVR2A Protein, Human, Recombinant (His)

activin A receptor, type IIA,ACVR2,ACTRII

Human HEK293 Cells
ACVR2A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.9 kDa and the accession number is P27037-1.
TMPK-00887 KIR3DL2 Protein, Human, Recombinant (His & Avi)

KIR3DL2,p140,NKAT4,NKAT4A,NKAT4B,CL-5,CD15...

Human HEK293 Cells
KIR3DL2 is a member of the killer cell immunoglobulin-like receptor (KIR) family that was initially identified at the surface of natural killer (NK) cells. KIR3DL2, also known as CD158k, is expressed as a disulfide-linked homodimer. Each chain is composed of three immunoglobulin-like domains and a long cytoplasmic tail containing two immunoreceptor tyrosine-based inhibitory motifs. KIR3DL2 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The pred...
TMPY-00150 IGF2/IGF-II Protein, Human, Recombinant

PP9974,胰岛素样生长因子,C11orf43,IGF-II,insulin-li...

Human P. pastoris (Yeast)
Insulin-like growth factor 2 (IGF-2/IGF-II) is a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumor, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. IGF-2/IGF-II is a mediator of prolactin-induced alveologenesis; prolactin, IGF-2, and cyclin D1, all of which are overexpressed in br...
TMPK-01207 DLL3 Protein, Human, Recombinant (His & Avi), Biotinylated

Pudgy,δ3,SCDO1δ3,Delta3,SCDO1delta3,SCDO

Human HEK293 Cells
Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). DLL3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight ...
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重组蛋白

AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04451
Species: Human
Expression System: Baculovirus Insect Cells
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)
Cat.No: TMPY-03878
Species: Human
Expression System: HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant
Cat.No: TMPY-02501
Species: Human
Expression System: HEK293 Cells
CD82 Protein, Human, Recombinant (His)
Cat.No: TMPY-02030
Species: Human
Expression System: HEK293 Cells
SIGIRR Protein, Human, Recombinant (His)
Cat.No: TMPY-01894
Species: Human
Expression System: HEK293 Cells
FLT3 Protein, Human, Recombinant (T227M, His)
Cat.No: TMPY-01247
Species: Human
Expression System: HEK293 Cells
Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)
Cat.No: TMPY-02779
Species: Human
Expression System: Baculovirus Insect Cells
HGF Protein, Mouse, Recombinant
Cat.No: TMPY-03290
Species: Mouse
Expression System: HEK293 Cells
TIGIT Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04970
Species: Human
Expression System: HEK293 Cells
R-Spondin 1/RSPO1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01147
Species: Human
Expression System: HEK293 Cells
PD-L2 Protein, Human, Recombinant (His)
Cat.No: TMPY-04346
Species: Human
Expression System: HEK293 Cells
VCAM-1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00947
Species: Human
Expression System: HEK293 Cells
CD19 Protein, Human, Recombinant (His)
Cat.No: TMPY-01949
Species: Human
Expression System: HEK293 Cells
FGFR3 Protein, Human, Recombinant (His)
Cat.No: TMPY-04165
Species: Human
Expression System: HEK293 Cells
IgG1 Fc Protein, Human, Recombinant (C103S)
Cat.No: TMPY-00820
Species: Human
Expression System: HEK293 Cells
Insulin Receptor Protein, Human, Recombinant (long isoform, His)
Cat.No: TMPY-01146
Species: Human
Expression System: HEK293 Cells
CTLA-4 Protein, Human, Recombinant (His)
Cat.No: TMPY-04348
Species: Human
Expression System: HEK293 Cells
ErbB4 Protein, Human, Rhesus, Recombinant (His)
Cat.No: TMPY-02813
Species: Human,Rhesus
Expression System: HEK293 Cells
TSLP Protein, Human, Recombinant (R127A & R130S, His)
Cat.No: TMPY-05220
Species: Human
Expression System: HEK293 Cells
CD30/TNFRSF8 Protein, Human, Recombinant (His)
Cat.No: TMPY-01827
Species: Human
Expression System: HEK293 Cells
IL-1RA Protein, Human, Recombinant
Cat.No: TMPY-00853
Species: Human
Expression System: E. coli
CEACAM3 Protein, Human, Recombinant (His)
Cat.No: TMPY-01850
Species: Human
Expression System: HEK293 Cells
SNAP-25 Protein, Human, Recombinant (His)
Cat.No: TMPY-02245
Species: Human
Expression System: E. coli
LOXL2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00203
Species: Mouse
Expression System: HEK293 Cells
ACVR2B Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01281
Species: Mouse
Expression System: HEK293 Cells
CD73 Protein, Human, Recombinant (His)
Cat.No: TMPY-01851
Species: Human
Expression System: HEK293 Cells
RGMA Protein, Human, Recombinant (His)
Cat.No: TMPY-02525
Species: Human
Expression System: HEK293 Cells
BTN3A3 Protein, Human, Recombinant (His)
Cat.No: TMPY-03967
Species: Human
Expression System: HEK293 Cells
PD-L1 Protein, Human, Recombinant
Cat.No: TMPY-05208
Species: Human
Expression System: HEK293 Cells
Progranulin Protein, Human, Recombinant (His)
Cat.No: TMPY-00978
Species: Human
Expression System: HEK293 Cells
NQO1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03407
Species: Human
Expression System: E. coli
IL-13RA1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01258
Species: Human
Expression System: HEK293 Cells
PSGL-1/CD162 Protein, Human, Recombinant (His)
Cat.No: TMPY-03531
Species: Human
Expression System: HEK293 Cells
EPOR Protein, Human, Recombinant (His)
Cat.No: TMPY-01883
Species: Human
Expression System: HEK293 Cells
IL-4 Protein, Human, Recombinant
Cat.No: TMPY-01862
Species: Human
Expression System: E. coli
R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-06418
Species: Human
Expression System: HEK293 Cells
LRRC15 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04333
Species: Human
Expression System: HEK293 Cells
CD44 Protein, Human, Recombinant (His)
Cat.No: TMPY-02033
Species: Human
Expression System: HEK293 Cells
LIF Protein, Human, Recombinant
Cat.No: TMPY-04104
Species: Human
Expression System: HEK293 Cells
LAG-3 Protein, Human, Recombinant
Cat.No: TMPY-04939
Species: Human
Expression System: HEK293 Cells
IL-33 Protein, Human, Recombinant
Cat.No: TMPY-00861
Species: Human
Expression System: E. coli
FLT3 Ligand Protein, Human, Recombinant
Cat.No: TMPY-06873
Species: Human
Expression System: E. coli
DR5/TRAIL R2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01185
Species: Human
Expression System: HEK293 Cells
CD98 Protein, Human, Recombinant (His)
Cat.No: TMPY-01938
Species: Human
Expression System: HEK293 Cells
HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His)
Cat.No: TMPY-01137
Species: Human
Expression System: HEK293 Cells
LILRB5/CD85c Protein, Human, Recombinant (His)
Cat.No: TMPY-04826
Species: Human
Expression System: HEK293 Cells
ACVR2A Protein, Human, Recombinant (His)
Cat.No: TMPY-01744
Species: Human
Expression System: HEK293 Cells
KIR3DL2 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00887
Species: Human
Expression System: HEK293 Cells
IGF2/IGF-II Protein, Human, Recombinant
Cat.No: TMPY-00150
Species: Human
Expression System: P. pastoris (Yeast)
DLL3 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-01207
Species: Human
Expression System: HEK293 Cells
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