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Search Results for " hev "

Targets Recommended: Others Virus Protease

15

抑制剂 & 化合物

20

天然产物

9

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T6516	Golgicide A	Others; Virus Protease	Microbiology/Virology; Others
	Golgicide A 可抑制柯萨奇病毒 B3 和其他人类肠道病毒的复制。它是一种高度特异性可逆的顺式高尔基体 ADP-核糖基化因子鸟嘌呤核苷酸交换因子抑制剂。
T16967	T-00127_HEV1	PI4K	PI3K/Akt/mTOR signaling
	T-00127_HEV1 是有效的phosphatidylinositol 4-kinase III beta 抑制剂，IC50为 60 nM。
T2432	PD 169316	Virus Protease; p38 MAPK; Autophagy	Autophagy; MAPK; Microbiology/Virology
	PD 169316 是一种细胞渗透性 p38 MAP 激酶抑制剂，IC50值为 89 nM。它可选择性地抑制磷酸化 p38 的激酶活性。
T4061	LY2334737	Nucleoside Antimetabolite/Analog; Others; Virus Protease	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others
	LY2334737 是一种具有口服活性的 Gemcitabine 的前药，也是核苷类似物。它抑制肠道病毒 A71 感染，有抗病毒和抗癌活性。
T1750	Pirodavir R77975,吡罗达韦	Virus Protease; Antiviral	Immunology/Inflammation; Microbiology/Virology
	Pirodavir (R77975) 是一种广谱抗小核糖核酸病毒抑制剂，有效抑制人鼻病毒衣壳的结合。
T18928	Brilliant Black BN 亮黑1,E 151	Others; Virus Protease	Microbiology/Virology; Others
	Brilliant Black BN (E 151) 是一种偶氮染料和一种食品着色剂。它抑制 EV71 与其细胞脱壳因子亲环蛋白 A 之间的相互作用，是一种很有前途的抗 EV71 感染的抗病毒药物。
T4536	Pleconaril VP 63843,Win 63843,Picovir,普可那利	Virus Protease; Antiviral	Immunology/Inflammation; Microbiology/Virology
	Pleconaril (VP 63843) 是一种有潜力研究肠病毒的衣壳抑制剂,，它可有效抑制复制, IC50值为 50 nM。
T4492	pocapavir SCH-48973,V-073	Virus Protease; Antiviral	Immunology/Inflammation; Microbiology/Virology
	Pocapavir (SCH-48973) 是一种具有口服活性的研究性肠道病毒衣壳抑制剂，可防止病毒粒子进入细胞后脱壳。
T0188	Fluticasone (propionate) 丙酸氟替卡松,CCI-187881,氟替卡松丙酸酯,Fluticasone propionate	Glucocorticoid Receptor; Virus Protease; Estrogen/progestogen Receptor; Phospholipase; Endogenous Metabolite; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; Endocrinology/Hormones; Metabolism; Microbiology/Virology
	Fluticasone propionate (CCI-187881) 是一种选择性糖皮质激素受体激动剂，是一种局部抗炎激素，亲和力KD 为 0.5 nM。具有抗病毒活性。
T8498	EIDD-1931 Beta-d-N4-hydroxycytidine	Virus Protease; HCV Protease; SARS-CoV; Topoisomerase	DNA Damage/DNA Repair; Microbiology/Virology; Proteases/Proteasome
	EIDD-1931 (Beta-d-N4-hydroxycytidine) 是一种核苷类抗病毒试剂，可抑制丙型肝炎病毒、基孔肯亚病毒和委内瑞拉马脑炎病毒的复制活性。
T36814	Chevalone B	Others	Others
	Chevalone B is a meroterpenoid originally isolated from the fungus E. chevalieri. It is cytotoxic to KB and NCI-H187 cells with IC50 values of 2.9 and 9.8 μg/ml, respectively.
T34840	Thevetose, L- Thevetose L-form	Others	Others
	Thevetose, L- is a bioactive chemical.
T124930	Thevetin A	Others	Others
	Thevetin A 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T124930，CAS号为 37933-66-7。
T34026	Phevamine A PHVA	Others	Others
	Phevamine A (PHVA) 是植物免疫反应的抑制剂。
T131628	Digitoxigenin (Thevetigenin; Echujetin; Cerberigenin)	Others	Others
	Digitoxigenin (Thevetigenin; Echujetin; Cerberigenin) 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T131628。

化合物

Cat.No: T6516

Target: Others, Virus Protease

Cat.No: T16967

Target: PI4K

Cat.No: T2432

Target: Virus Protease, p38 MAPK, Autophagy

Cat.No: T4061

Target: Nucleoside Antimetabolite/Analog, Others, Virus Protease

Cat.No: T1750

Synonym: R77975,吡罗达韦

Target: Virus Protease, Antiviral

Brilliant Black BN

Cat.No: T18928

Synonym: 亮黑1,E 151

Target: Others, Virus Protease

Cat.No: T4536

Synonym: VP 63843,Win 63843,Picovir,普可那利

Target: Virus Protease, Antiviral

Cat.No: T4492

Synonym: SCH-48973,V-073

Target: Virus Protease, Antiviral

Fluticasone (propionate)

Cat.No: T0188

Synonym: 丙酸氟替卡松,CCI-187881,氟替卡松丙酸酯,Fluticasone propionate

Target: Glucocorticoid Receptor, Virus Protease, Estrogen/progestogen Receptor, Phospholipase, Endogenous Metabolite, ADC Cytotoxin

Cat.No: T8498

Synonym: Beta-d-N4-hydroxycytidine

Target: Virus Protease, HCV Protease, SARS-CoV, Topoisomerase

Cat.No: T36814

Target: Others

Cat.No: T34840

Synonym: Thevetose L-form

Target: Others

Cat.No: T124930

Target: Others

Cat.No: T34026

Synonym: PHVA

Target: Others

Digitoxigenin (Thevetigenin; Echujetin; Cerberigenin)

Cat.No: T131628

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T5779	MOSLOFLAVONE	IL Receptor; Virus Protease; TNF; Antibacterial	Apoptosis; Immunology/Inflammation; Microbiology/Virology
	Mosloflavone 从Scutellaria baicalensis Georgi 中分离出的类黄酮，具有抗EV71活性。它可抑制铜绿假单胞菌的毒力和生物膜形成，有作为杀菌剂的潜力。它在病毒感染的初始阶段抑制 VP2 病毒复制和蛋白质表达，并抑制病毒 VP2 衣壳蛋白合成。
T5S2360	Corydaline Corydalin,紫堇碱,延胡索甲素,(+)-Corydaline	P450; Virus Protease; Opioid Receptor; AChE	Endocrinology/Hormones; GPCR/G Protein; Metabolism; Microbiology/Virology; Neuroscience
	Corydaline (Corydalin) 是从 Corydalis yanhusuo 提取的一种异喹啉生物碱，是一种新型促动力植物药的主要活性成分之一。它促进胃排空和小肠转运，促进胃的调节，具有抗乙酰胆碱酯酶、抗过敏和镇痛活性。
T8205	Norwogonin 5,7,8-Trihydroxyflavone,去甲汉黄芩素	Virus Protease	Microbiology/Virology
	Norwogonin (5,7,8-Trihydroxyflavone) 是从黄芩中分离出来的，对肠道病毒 71 具有抗病毒活性，IC50为 31.83 μg/ ml。
T3345	Hederasaponin B 常春藤皂苷B,Eleutheroside M,刺五加叶中,Hederacoside B	Others; Virus Protease	Microbiology/Virology; Others
	Hederasaponin B (Hederacoside B) 是从Hedera helix 中分离的，有广谱抗病毒活性。
T1670	Lanatoside C Cedilanid,Ceglunate,Isolanid,毛花甙丙,毛花苷C	ATPase; Virus Protease; Autophagy	Autophagy; Membrane transporter/Ion channel; Microbiology/Virology
	Lanatoside C (Ceglunate) 是一种可用于治疗充血性心力衰竭和心律失常的强心苷类药物。它作用于 HuH-7细胞，可抗登革病毒感染， IC50为0.19 μM。
TN2111	Prunin Naringenin 7-0-glucoside,柚皮素-7-O-葡萄糖苷	Phosphatase; Anti-infection; Virus Protease	Metabolism; Microbiology/Virology
	Prunin (Naringenin 7-0-glucoside) 是一种人肠道病毒 A71 抑制剂。它抑制蛋白酪氨酸磷酸酶 1B，IC50值为 5.5 μM。
TN5297	Glaucogenin C mono-D-thevetoside
	Glaucogenin C mono-D-thevetoside is a natural product from Cynanchum stauntonii.
T79982	2'-epi-2'-O-Acetylthevetin B GHSC-74	Apoptosis	Apoptosis
	2'-epi-2'-O-Acetylthevetin B (GHSC-74) 为源自Cerbera manghas L种子的强心苷，其抑制HepG2细胞增殖并诱导细胞凋亡(apoptosis)及线粒体膜电位降低。
TN1734	Heveaflavone 橡胶树双黄酮	Antioxidant; Topoisomerase	DNA Damage/DNA Repair; oxidation-reduction
	Heveaflavone 抑制拓扑异构酶 I 并清除 DPPH 自由基，具有抗增殖和抗氧化作用。
T82782	Cannogenol 3-O-β-gentiobiosyl-(1→4)-α-L-thevetoside
	Cannogenol 3-O-β-gentiobisyl-(1→4)-α-L-thevetoside (Compound 12) 是从Thevetia peruvian的种子中分离得到的强心苷化合物。它对SW1990和MGC-803细胞表现出细胞毒性，其IC50分别为9.52 μM和7.70 μM。
TN2656	17alpha-Thevebioside	Others	Others
	17alpha-Thevebioside 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN2656，CAS号为 114613-59-1。
T36815	Chevalone C	Others	Others
	Chevalone C is a meroterpenoid fungal metabolite originally isolated from E. chevalieri. It is active against M. tuberculosis H37Ra (MIC = 6.3 μg/ml) and is cytotoxic to BC1 human breast cancer cells (IC50 = 8.7 μg/ml). Chevalone C inhibits the growth of multidrug-resistant isolates of E. coli, S. aureus, and E. faecium in a disc diffusion assay when used at a concentration of 15 μg/disc. It also induces cell death in HCT116 colorectal carcinoma cells.
T13922	Thevetiaflavone 2-Genistein-5-methyl ether,Apigenin-5-methyl ether	BCL; Caspase	Apoptosis; Proteases/Proteasome
	Thevetiaflavone (2-Genistein-5-methyl ether) 是一种来自 Wikstroemia indica 的天然类黄酮，可抑制乳酸脱氢酶从细胞质中泄漏并提高细胞活力。
T83189	Acetylthevetin A
	Acetylthevetin A，一种从夹竹桃(Cascabela thevetioides)中分离出的天然产物。
TQ0102	Theviridoside	Others	Others
	Theviridoside is a natural product found in the leaves of Cerbera odollam.
TN7533	Chevalone E Deacetylchevalone C	Others	Others
	Chevalone E, a meroterpene identified in A. similanensis, exhibits significant properties.
TN2696	2,3-Dihydroheveaflavone	Others	Others
	2,3-Dihydroheveaflavone 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN2696，CAS号为 110382-42-8。
TN5141	Thevetin B	ATPase; Potassium Channel; Sodium Channel	Membrane transporter/Ion channel
	Thevetin B 是一种强心苷，是Na+-, K+-依赖性腺苷三磷酸酶 (Na+,K+-ATPase) 的抑制剂，来自 Thevetia peruviana。
T80702	α-Thevetin B
	α-Thevetin B（Compound 24）, 一种从Thevetia peruviana分离得到的心脏苷，用于肺癌、胃癌和胰腺癌的研究。
TN5289	Thevebioside Digitoxigenin glucosylthevetoside
	Thevebioside and digitoxin are cardiac glycosides, have cardiac action.

天然产物

Cat.No: T5779

Target: IL Receptor, Virus Protease, TNF, Antibacterial

Cat.No: T5S2360

Synonym: Corydalin,紫堇碱,延胡索甲素,(+)-Corydaline

Target: P450, Virus Protease, Opioid Receptor, AChE

Cat.No: T8205

Synonym: 5,7,8-Trihydroxyflavone,去甲汉黄芩素

Target: Virus Protease

Hederasaponin B

Cat.No: T3345

Synonym: 常春藤皂苷B,Eleutheroside M,刺五加叶中,Hederacoside B

Target: Others, Virus Protease

Cat.No: T1670

Synonym: Cedilanid,Ceglunate,Isolanid,毛花甙丙,毛花苷C

Target: ATPase, Virus Protease, Autophagy

Cat.No: TN2111

Synonym: Naringenin 7-0-glucoside,柚皮素-7-O-葡萄糖苷

Target: Phosphatase, Anti-infection, Virus Protease

Glaucogenin C mono-D-thevetoside

Cat.No: TN5297

2'-epi-2'-O-Acetylthevetin B

Cat.No: T79982

Synonym: GHSC-74

Target: Apoptosis

Cat.No: TN1734

Synonym: 橡胶树双黄酮

Target: Antioxidant, Topoisomerase

Cannogenol 3-O-β-gentiobiosyl-(1→4)-α-L-thevetoside

Cat.No: T82782

17alpha-Thevebioside

Cat.No: TN2656

Target: Others

Cat.No: T36815

Target: Others

Thevetiaflavone

Cat.No: T13922

Synonym: 2-Genistein-5-methyl ether,Apigenin-5-methyl ether

Target: BCL, Caspase

Acetylthevetin A

Cat.No: T83189

Cat.No: TQ0102

Target: Others

Cat.No: TN7533

Synonym: Deacetylchevalone C

Target: Others

2,3-Dihydroheveaflavone

Cat.No: TN2696

Target: Others

Cat.No: TN5141

Target: ATPase, Potassium Channel, Sodium Channel

Cat.No: T80702

Cat.No: TN5289

Synonym: Digitoxigenin glucosylthevetoside

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00300	Hendra virus (HeV) (isolate Horse/Autralia/Hendra/1994) Glycoprotein Protein (hFc) HeV-G Protein, HeV,Glycoprotein Protein, <...	HEV	HEK293 Cells
	Hendra virus (HeV) (isolate Horse/Autralia/Hendra/1994) Glycoprotein Protein (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 86.3 kDa and the accession number is O89343.
TMPY-00861	IL-33 Protein, Human, Recombinant IL1F11,C9orf26,NFEHEV,NF-HEV,DVS27,白介素,int...	Human	E. coli
	IL-33 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18 kDa and the accession number is O95760-1.
TMPJ-01210	IL-33 Protein, Mouse, Recombinant Interleukin-1 family member 11,白细胞介素,NF-HEV and IL-...	Mouse	E. coli
	Mouse Interleukin 33 (IL-33) is a 30 kDa proinflammatory cytokine which may also regulates gene transcription in producer cells. IL-33 is constitutively expressed in smooth muscle and airway epithelia. IL-33 was identified based on sequence and structural homology with IL-1 family cytokines. It is up‑regulated in arterial smooth muscle, dermal fibroblasts, and keratinocytes following IL-1 alpha or IL‑1 beta stimulation. IL-33 is structurally related to IL-1, which induces helper T cells to produ...
TMPK-00163	IL-33 Protein, Cynomolgus, Recombinant (His) IL1F11,C9orf26 Z,C9ORF26,DV27,RP11-575C20.2,NFEHEV,...	Cynomolgus	HEK293 Cells
	Interleukin-33 (IL-33) is a cytokine belonging to the IL-1 family, playing a role in inflammatory, infectious and autoimmune diseases and expressed in the cellular nucleus in several tissues. High levels of IL-33 are expressed in epithelial barrier tissues and endothelial barriers. ST2 is a receptor for IL-33, expressed selectively on a subset of Th2 cells, mediating some of their functions.
TMPH-00814	Hepatitis E virus genotype 3 (HEV-3) Capsid protein (His) Pro-secreted protein ORF2,Protein ORF2	HEV-3	P. pastoris (Yeast)
	Major viral capsid protein that encapsidates the viral genome. Binds to the 5' end of the genomic RNA. Hepatitis E virus genotype 3 (HEV-3) Capsid protein (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 29.3 kDa and the accession number is Q9YLQ9.
TMPH-00812	Hepatitis E virus genotype 1 (HEV-1) Protein ORF3 (His & SUMO) Protein ORF3	HEV-1	E. coli
	Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins involved in vesicle formation pathway. Acts also as a viroporin and forms ion conductive pores allowing viral particle release. Impairs the generation of type I interferon by downregulating host TLR3 and TLR7 as well as their downstream signaling pathways. Hepatitis E virus genotype 1 (HEV-1) Protein ORF3 (His & SUMO) is...
TMPH-00813	Hepatitis E virus genotype 1 (HEV-1) Secreted protein ORF2 (His) Protein ORF2,Pro-secreted protein ORF2	HEV-1	Baculovirus Insect Cells
	Plays a role in the inhibition of host antibody-mediated neutralization without blocking viral cell entry.; Forms an icosahedral capsid with a T=1 symmetry and a 34 nm diameter. The capsid is composed of 60 copies linked to each other. Binds to the 5' end of the genomic RNA to mediate genome encapsidation. Binds to heparin surface proteoglycans (HSPGs) to mediate viral entry. Additionally, the interactions with host ASGR1 and ASGR2 facilitate viral infection of hepatocytes. Hepatitis E virus gen...
TMPJ-00617	IL-33 Protein, Rhesus macaque, Recombinant (His) Interleukin-33,IL1F11,IL33,白介素,白细胞介素,IL-1F11,Interleukin-1 F...	Rhesus	E. coli
	Interleukin-33 (IL-33) belongs to the IL-1 superfamily. IL33 is highly expressed in endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes, but almost undetectable in placenta. IL33 induces the production of T helper-2 (Th2)-associated cytokines. IL-33 is a cytokine that mediates its biological effects by binding to and signals through IL1RL1/ST2 and IL-1 Receptor Accessory Protein (IL1RAP), activating intracellular molecules in the NF-κB and MAP kinase signaling pathways...
TMPH-00819	Pro-hevein Protein, Hevea brasiliensis, Recombinant (His) HEV1,Pro-hevein,Major hevein	Hevea brasiliensis	E. coli
	N-acetyl-D-glucosamine / N-acetyl-D-neuraminic acid binding lectin. Can inhibit fungal growth. Pro-hevein Protein, Hevea brasiliensis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 24.1 kDa and the accession number is P02877.

重组蛋白

Hendra virus (HeV) (isolate Horse/Autralia/Hendra/1994) Glycoprotein Protein (hFc)

Cat.No: TMPY-00300

Species: HEV

Expression System: HEK293 Cells

IL-33 Protein, Human, Recombinant

Cat.No: TMPY-00861

Species: Human

Expression System: E. coli

IL-33 Protein, Mouse, Recombinant

Cat.No: TMPJ-01210

Species: Mouse

Expression System: E. coli

IL-33 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00163

Species: Cynomolgus

Expression System: HEK293 Cells

Hepatitis E virus genotype 3 (HEV-3) Capsid protein (His)

Cat.No: TMPH-00814

Species: HEV-3

Expression System: P. pastoris (Yeast)

Hepatitis E virus genotype 1 (HEV-1) Protein ORF3 (His & SUMO)

Cat.No: TMPH-00812

Species: HEV-1

Expression System: E. coli

Hepatitis E virus genotype 1 (HEV-1) Secreted protein ORF2 (His)

Cat.No: TMPH-00813

Species: HEV-1

Expression System: Baculovirus Insect Cells

IL-33 Protein, Rhesus macaque, Recombinant (His)

Cat.No: TMPJ-00617

Species: Rhesus

Expression System: E. coli

Pro-hevein Protein, Hevea brasiliensis, Recombinant (His)

Cat.No: TMPH-00819

Species: Hevea brasiliensis

Expression System: E. coli

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