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Targets Recommended: Others 5-HT Receptor Adenosine Receptor

131

抑制剂 & 化合物

10

天然产物

5658

重组蛋白

1

同位素标记化合物

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Cat. No. Product Name Target Signaling Pathways
T16378 Ogerin

Others; 5-HT Receptor; Adenosine Receptor GPCR/G Protein; Neuroscience; Others
Ogerin 是选择性 GPR68正向别构调节剂(pEC50:6.83)。它能够抑制小鼠对恐惧记忆的回忆。它对 A2A 受体具有适中的拮抗作用(Ki:220 nM)。对 5-HT2B 受体的拮抗作用较弱(Ki:736 nM)。
T60003 AC1-IN-1

Adenylyl cyclase Neuroscience
AC1-IN-1 是 1 型腺苷酸环化酶的选择性抑制剂(AC1,IC50 = 0.54 µM)。
T3174 Taprenepag

CP-544326

Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
Taprenepag (CP-544326) 是一种有效的选择性前列腺素 E2 受体激动剂,EC50为 2.8 nM,可用于研究开角治疗高眼压和青光眼的试验。
T11211 EP4 receptor antagonist 1

Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
EP4 receptor antagonist 1 是一种有效的特异性前列腺素 EP4受体拮抗剂,对人和小鼠 EP4受体的 IC50分别为6.1 nM 和16.2 nM。 EP4 receptor antagonist 1 可用于癌症免疫治疗的研究。
T4378 MS049

Histone Methyltransferase Chromatin/Epigenetic
MS049 是一种有效的、选择性的和细胞活性的 PRMT4 和 PRMT6 双重抑制剂,IC50 分别为 34 和 43 nM。它可降低 HEK293 细胞的 Med12me2a 和 H3R2me2a 水平。
T22990 ML-090

Fluoflavine

NADPH-oxidase; Others Immunology/Inflammation; Others
ML-090 是 NOX1 特异性抑制剂 (IC50 = 90 nM),对 NOX1 的特异性高于 NOX2、NOX3、NOX4(所有 IC50 > 10 μM)100倍。
T8596 Ceefourin 1

MRP Immunology/Inflammation
Ceefourin 1 是一种具有高度选择性的多药抗性蛋白 4 (MRP4) 抑制剂。它能够抑制多种 MRP4 底物的转运,但对其他 ABC 转运蛋白无影响。它是苯并噻唑,常作为高危神经母细胞瘤的化学增敏剂。
T28804 Slingshot inhibitor D3

JHN76359

Others Others
Slingshot inhibitor D3 (JHN76359) 是具有选择性、竞争性、可逆性的Slingshot 抑制剂。它对Slingshot 1和Slingshot 2具有相似的抑制活性。它对Slingshot 1 的IC50为 3 μM;对Slingshot 2 的Ki 为 3.9 μM。
T5399 GeA-69

PARP Chromatin/Epigenetic; DNA Damage/DNA Repair
GeA-69 是一种选择性变构 PARP14 大结构域 2 (MD2) 抑制剂,Kd 值为 2.1 µM。
T7155 JH-II-127

LRRK2 Autophagy
JH-II-127是一种高选择性的脑渗透性 LRRK2 抑制剂,抑制野生型 LRRK2、G2019S LRRK2和 A2016T LRRK2,IC50 值分别为6.6 nM、2.2 nM 和 47.7 nM。
T2694 KN-62

CaMK; P2X Receptor; Autophagy Autophagy; Membrane transporter/Ion channel; Neuroscience
KN-62 是一种选择性的、可逆的钙调蛋白依赖性蛋白激酶 II (CaMK-II) 抑制剂,直接与 CaMK-II 酶的钙调蛋白结合位点结合,对大鼠脑 CaMK-II 的IC50值为 0.9 μM。它是非竞争性的P2X7受体拮抗剂,IC50约为 15 nM。
T13884 Shield-1

Others Others
Shield-1 是 FK506 结合蛋白 12 (FKBP) 的特异性、高亲和力和细胞渗透性配体,通过与突变的 FKBP (mtFKBP) 结合来逆转不稳定性,允许 mtFKBP 融合蛋白的条件表达。它可以稳定整个融合蛋白。
T8851 I3MT-3

HMPSNE

Hippo pathway Stem Cells
I3MT-3 (HMPSNE) 是一种有效的、具有细胞膜渗透性的、选择性的 3-巯基丙酮酸硫转移酶 (3MST)的抑制剂,IC50值为2.7 μM,对其他硫化氢/磺胺制硫酶没有活性。它靶向位于 3MST 活性位点的过硫半胱氨酸残基。
T16014 Mavatrep

JNJ-39439335

TRP/TRPV Channel Membrane transporter/Ion channel
Mavatrep (JNJ-39439335) 是一种特异性的 TRPV1 拮抗剂,Ki 为 6.5 nM,可用于炎症性疼痛的研究。
T17258 WRG-28

Discoidin Domain Receptor (DDR) Tyrosine Kinase/Adaptors
WRG-28 是一种选择性的、细胞外作用的DDR2变构抑制剂 (IC50:230 nM)。它通过受体的变构调节特异地抑制受体-配体相互作用。它通过靶向 DDR2 抑制肿瘤侵袭和迁移,基质的肿瘤支持作用,能够抑制肺中的转移性乳腺肿瘤细胞定植。
T19840 GSK-F1

PI4KA inhibitor-F1

PI4K PI3K/Akt/mTOR signaling
GSK-F1 (PI4KA inhibitor-F1) 是一种新型强效 PI4KA 抑制剂。
T9240 sulfopin

Acetamide, 2-chloro-N-(2,2-dimethylpropyl)-N-(tetrahydro-1,1-dioxido-3-thienyl)-

Others Others
Sulfopin 是高选择性共价Pin1抑制剂(Ki:17 nM),在体内能够阻断 Myc 驱动的肿瘤。其中肽基脯氨酰异构酶 Pin1 在癌症中被用来激活癌基因和灭活肿瘤抑制因子。
T9564 IRE1α kinase-IN-1

IRE1 Cell Cycle/Checkpoint
IRE1α kinase-IN-1 是IRE1α 的选择性抑制剂(IC50为 77 nM),对 IRE1α 的选择性高于 IRE1β 亚型 100 倍。它抑制内质网诱导的 IRE1α 寡聚和自磷酸化,并抑制 IRE1α RNase 活性 (IC50=80 nM)。
T2036 6-OAU

GTPL5846

GPR Endocrinology/Hormones; GPCR/G Protein
6-OAU (GTPL5846) 是 GPR84 的替代激动剂,在 Gqi5 嵌合体存在的情况下,在 HEK293 细胞中激活人 GPR84,在 PI 测定中 EC50 为 105 nM。
T7196 HG-10-102-01

[4-[[5-氯-4-(甲基氨基)-2-嘧啶基]氨基]-3-甲氧基苯基]-4-吗啉基甲酮

LRRK2 Autophagy
HG-10-102-01 是富含亮氨酸重复激酶 2 和突变型G2019S 抑制剂,IC50分别为20.3 nM 和3.2 nM。
T14673 BMS 299897

Beta Amyloid; Gamma-secretase Neuroscience; Proteases/Proteasome; Stem Cells
BMS 299897 是一种磺胺类 γ 分泌酶抑制剂。它在稳定过表达淀粉样前体蛋白(APP)的 HEK293 细胞中抑制 Aβ 生成的 IC50 值为 7 nM。
T60627 ELOVL1-IN-2

Others Others
ELOVL1-IN-2 是一种被称为极长链脂肪酸 1 (ELOVL1) 酶延长抑制剂的化合物,对 ELOVL1 表现出微弱的抑制作用(IC50 为 21 μM),并在原代细胞中表现出中等效力。对 HEK293 C26 细胞进行测定(IC50 为 6.7 μM)[1]。
T2092 Amitifadine hydrochloride

DOV-21947 hydrochloride,EB-1010 hydrochloride

Dopamine Receptor; 5-HT Receptor; Serotonin Transporter; Norepinephrine GPCR/G Protein; Neuroscience
Amitifadine hydrochloride (EB-1010 hydrochloride) 是一种 5-羟色胺-去甲肾上腺素-多巴胺的再摄取抑制剂(SNDRI),其在 HEK 293 细胞中测得的 IC50值分别为 12, 23, 96 nM。
T6245 BAPTA-AM

BAPTA/AM

Potassium Channel Membrane transporter/Ion channel
BAPTA-AM 是一种钙离子螯合剂,具有细胞渗透性和选择性,可以阻断 hERG、hKv1.3 和 hKv1.5 通道 (IC50=1.3/1.45/1.23 μM)。BAPTA-AM对 Ca2+的亲和力是 Mg2+的 105 倍,可以用于钙在细胞信号传导中的作用。
T11718 JI051

JI-051

Gamma-secretase Neuroscience; Proteases/Proteasome; Stem Cells
JI051 具有抗肿瘤作用,能够与癌症相关蛋白伴侣 prohibitin 2 (PHB2) 相互作用,通过抑制 Notch 下游效应基因 Hes1 转录来促使细胞周期停滞,抑制HEK293 细胞和胰腺癌细胞增殖。
T11720 JNJ-18038683

5-HT Receptor GPCR/G Protein; Neuroscience
JNJ-18038683 是 5-羟色胺受体 7 拮抗剂,HEK293 细胞中检测出其对大鼠和人类 5-羟色胺受体 7 的pKi 值分别为 8.19和8.20。
T37428 TRPC6-PAM-C20

TRPC6-PAM-C20,3-(6,7-Dimethoxy-3,3-dimethyl-3,4-dihydro-isoquinolin-1-yl)-chromen-2-one

TRP/TRPV Channel Membrane transporter/Ion channel
TRPC6-PAM-C20 是一种选择性 TRPC6 正变构调节剂。 TRPC6-PAM-C20 在表达 TRPC6 的 HEK 细胞中诱导胞内 Ca2+ 瞬时增加,EC50 为 2.37 μM。 TRPC6-PAM-C20 增强 OAG 诱导的血小板聚集。
T2080 LCL161

IAP Apoptosis
LCL161 是一种 SMAC 模拟物,可有效结合并抑制多种 IAP。它抑制 HEK293 细胞中 XIAP 和 MDA-MB-231细胞中 cIAP1的 IC50分别为 35 和 0.4 nM。
T1842 XMD17-109

XMD17 109,ERK5-IN-1

ERK MAPK
XMD17-109 (ERK5-IN-1) 是一种特异性的ERK-5抑制剂,在 HEK293 细胞系中的EC50为 4.2 μM。
T12323 ORM-15341

Androgen Receptor Endocrinology/Hormones
ORM-15341 是雄激素受体拮抗剂,作用于 AR-HEK293细胞(IC50:38 nM)。
T15677 KY1220

Wnt/beta-catenin Cytoskeletal Signaling; Stem Cells
KY1220 通过靶向 Wnt/β-连环蛋白通路,使 β-连环蛋白和 Ras 不稳定。 它在 HEK293 报告细胞中的 IC50 为 2.1 μM。
T11186 EMPA

OX Receptor GPCR/G Protein; Neuroscience
EMPA 是一种选择性、高亲和力和可逆的食欲素 OX2 受体拮抗剂,与人和大鼠 OX2-HEK293 膜结合,KD 值分别为 1.1 和 1.4 nM。
TP1263 Fz7-21

(Ac)-LPSDDLEFWCHVMY-NH2

Wnt/beta-catenin Cytoskeletal Signaling; Stem Cells
Fz7-21 ((Ac)-LPSDDLEFWCHVMY-NH2) 是一种 Frizzled 7 (FZD 7) 受体的肽抑制剂,能够选择性的与FZD7 CRD 亚类结合。它还阻断了WNT3A 介导的β-catenin 在小鼠L 细胞中的稳定作用。它对外源性WNT3A 刺激和转染WNT3A 或WNT1的HEK293细胞Wnt/β-catenin 信号传导有损伤。
T80666 2-PCCA hydrochloride

2-PCCA hydrochloride(1609624-97-6 Free base)

cAMP GPCR/G Protein
2-PCCA hydrochloride 是一种外消旋体,是一种具有有效性和选择性的 GPR88 受体激动剂,在 HEK293 细胞中显示出对 GPR88 介导的 cAMP 的产生有抑制作用,EC50 值为 116 nM。
T37292 M62812

TLR Immunology/Inflammation
M62812是一种 TLR4抑制剂,可在 HEK239细胞中抑制 LPS 诱导的NF-κB 活化。
T16106 ML224

NCGC00242364,ANTAG3

TSH Receptor GPCR/G Protein
ML224 (NCGC00242364) 是一种具有选择性和有效性的 TSHR 拮抗剂,可用于治疗 Graves 眼眶病、Graves 甲状腺功能亢进症和/或甲状腺癌。
T8414 SNC 80

Snc-80,SNC80,NIH 10815

Opioid Receptor Endocrinology/Hormones; GPCR/G Protein; Neuroscience
SNC 80 (NIH 10815) 是有效的,高度选择性的非肽类 δ 阿片 (δ-opioid) 受体激动剂,Ki 为1.78 nM,IC50 为 2.73 nM。SNC80 还以 EC50 为 52.8 nM 来选择性激活 HEK293 细胞中的 μ-δ 异聚体。SNC80 具有抗伤害性,抗痛觉过敏和抗抑郁样作用,并可用于多种头痛症的研究。
T21460 Teriparatide acetate

hPTH 1-34 (acetate salt),Parathar acetate,Forteo,醋酸立特帕肽

Others Others
Teriparatide acetate (Forteo) 是一种 PHT 激动剂,在 HEK293 细胞中的 IC50 为 2 nM。Teriparatide acetate 是一种重组形式的甲状旁腺激素。它是一种有效的合成代谢(即骨骼生长)剂,用于治疗某些形式的骨质疏松症。间歇使用特立帕肽比破骨细胞更能激活成骨细胞,从而导致骨骼整体增加。
T16510 PF-915275

Dehydrogenase Metabolism
PF-915275 是口服有效的人 11β-羟基类固醇脱氢酶1型选择性抑制剂,Ki 为 2.3 nM,在 HEK293 细胞中的EC50为 15 nM 。它对人和猴原代肝细胞中可的松向皮质醇的转化具有剂量依赖性,EC50分别为 20 nM 和 100 nM。
T16686 Pyr10

TRP/TRPV Channel Membrane transporter/Ion channel
Pyr10 是吡唑衍生物,是TRPC3通道的选择性抑制剂。Pyr10抑制卡巴可刺激的TRPC3转染的 HEK293 细胞中的 Ca2+流入。它具有区分受体操纵的TRPC3和天然基质相互作用分子 1 (STIM1)/Orai1 通道的能力。
T6911 NSC-87877 disodium

NSC87877

Apoptosis; Phosphatase Apoptosis; Metabolism
NSC-87877 disodium (NSC87877) 是一种有效的Shp2和Shp1蛋白质酪氨酸磷酸酶抑制剂,IC50值分别为0.318 μM 和0.355 μM。NSC-87877还抑制双特异性磷酸酶26。
T0816 Acetohexamide

Acetohexamid,醋磺环已脲,Dymelor,醋磺己脲,Gamadiabet

Potassium Channel; NADPH Membrane transporter/Ion channel; Metabolism
Acetohexamide (Acetohexamid) 是磺脲类试剂,可刺激胰腺分泌胰岛素,能够用于 2 型糖尿病的相关研究。
T15286 Flindokalner

BMS-204352

Potassium Channel Membrane transporter/Ion channel
Flindokalner (BMS-204352) 是一种钾离子通道调节剂。它是大电导钙激活 K 通道正向调节剂。它是在 HEK293 细胞中表达的所有神经元 Kv7通道亚型的正调节剂。它在 Kv7.1 通道 (Ki=3.7 μM) 处显示负调节活性,并充当 GABAA 受体的负调节剂。它在体内显示出抗焦虑功效。
T21890 JLK6

Gamma-secretase Neuroscience; Proteases/Proteasome; Stem Cells
JLK-6 是一种γ分泌酶抑制剂,选择性作用于 HEK293细胞的淀粉样β前体蛋白(APP)的γ-分泌酶裂解 APP,抑制 Aβ的生成,但对不 Notch 受体的裂解无影响。
T4532 Linrodostat

BMS-986205

IDO; Indoleamine 2,3-Dioxygenase (IDO) Metabolism
Linrodostat (BMS-986205) 是选择性的、不可逆的吲哚胺 2,3-双加氧酶 1(IDO1) 抑制剂,能够有效抑制 IDO1-HEK293 细胞,其IC50=1.1 nM。它在晚期癌症中具有良好的药理特性。
T8445 PU02

PU-02,6-[(1-Naphthalenylmethyl)thio]-9H-purine

Apoptosis; 5-HT Receptor Apoptosis; GPCR/G Protein; Neuroscience
PU02 (6-[(1-Naphthalenylmethyl)thio]-9H-purine) 是5-HT3受体的负变构调节剂,是 6-MP 的一个衍生物。它在 HEK293 细胞测得的转染 5-HT3A 和 5-HT3AB 受体后的 IC50值分别为 0.36 和 0.73 μM。
T38361 GSK717

IL Receptor; NOD Immunology/Inflammation; NF-κB
GSK717 是 NOD2(核苷酸结合寡聚结构域 2) 的选择性抑制剂。它抑制壁酰二肽 (MDP) 诱导的 NOD2 介导的信号转导,抑制 MDP 刺激的 HEK293/hNOD2 细胞分泌 IL-8 (IC50为 400 nM)。
T6891 MK-4101

Apoptosis; Hedgehog/Smoothened; Smo Apoptosis; GPCR/G Protein; Stem Cells
MK-4101 是一种 SMO 拮抗剂 ,对 293 细胞的 IC50为 1.1 µM。它也是一种 hedgehog 信号通路的有效抑制剂 ,对小鼠细胞和KYSE180 食管癌细胞的IC50分别为 1.5 µM 和 1 µM。它能抗肿瘤,抑制肿瘤细胞增殖并诱导细胞凋亡。
T11108 DSR-6434

TLR Immunology/Inflammation
DSR-6434仅在表达hTLR7的HEK293细胞中刺激TLR7活性,而在表达相似结构的hTLR8或hTLR9的HEK2 93细胞中不产生刺激效果。DSR-6434与特异性受体的结合会导致NF-κb 活化。
T13423 (1R,2R)-2-PCCA hydrochloride

(1R,2R)-2-PCCA(hydrochloride)

Others Others
(1R,2R)-2-PCCA hydrochloride 是一种具有有效性、选择性和可穿过血脑屏障的 GPR88 受体激动剂,在 WT 小鼠纹状体膜中 EC50 值为1140 n。(1R,2R)-2-PCCA hydrochloride 可用于研究中枢神经系统。

化合物

Ogerin
Cat.No: T16378
Synonym:
Target: Others, 5-HT Receptor, Adenosine Receptor
AC1-IN-1
Cat.No: T60003
Synonym:
Target: Adenylyl cyclase
Taprenepag
Cat.No: T3174
Synonym: CP-544326
Target: Prostaglandin Receptor
EP4 receptor antagonist 1
Cat.No: T11211
Synonym:
Target: Prostaglandin Receptor
MS049
Cat.No: T4378
Synonym:
Target: Histone Methyltransferase
ML-090
Cat.No: T22990
Synonym: Fluoflavine
Target: NADPH-oxidase, Others
Ceefourin 1
Cat.No: T8596
Synonym:
Target: MRP
Slingshot inhibitor D3
Cat.No: T28804
Synonym: JHN76359
Target: Others
GeA-69
Cat.No: T5399
Synonym:
Target: PARP
JH-II-127
Cat.No: T7155
Synonym:
Target: LRRK2
KN-62
Cat.No: T2694
Synonym:
Target: CaMK, P2X Receptor, Autophagy
Shield-1
Cat.No: T13884
Synonym:
Target: Others
I3MT-3
Cat.No: T8851
Synonym: HMPSNE
Target: Hippo pathway
Mavatrep
Cat.No: T16014
Synonym: JNJ-39439335
Target: TRP/TRPV Channel
WRG-28
Cat.No: T17258
Synonym:
Target: Discoidin Domain Receptor (DDR)
GSK-F1
Cat.No: T19840
Synonym: PI4KA inhibitor-F1
Target: PI4K
sulfopin
Cat.No: T9240
Synonym: Acetamide, 2-chloro-N-(2,2-dimethylpropyl)-N-(tetrahydro-1,1-dioxido-3-thienyl)-
Target: Others
IRE1α kinase-IN-1
Cat.No: T9564
Synonym:
Target: IRE1
6-OAU
Cat.No: T2036
Synonym: GTPL5846
Target: GPR
HG-10-102-01
Cat.No: T7196
Synonym: [4-[[5-氯-4-(甲基氨基)-2-嘧啶基]氨基]-3-甲氧基苯基]-4-吗啉基甲酮
Target: LRRK2
BMS 299897
Cat.No: T14673
Synonym:
Target: Beta Amyloid, Gamma-secretase
ELOVL1-IN-2
Cat.No: T60627
Synonym:
Target: Others
Amitifadine hydrochloride
Cat.No: T2092
Synonym: DOV-21947 hydrochloride,EB-1010 hydrochloride
Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Norepinephrine
BAPTA-AM
Cat.No: T6245
Synonym: BAPTA/AM
Target: Potassium Channel
JI051
Cat.No: T11718
Synonym: JI-051
Target: Gamma-secretase
JNJ-18038683
Cat.No: T11720
Synonym:
Target: 5-HT Receptor
TRPC6-PAM-C20
Cat.No: T37428
Synonym: TRPC6-PAM-C20,3-(6,7-Dimethoxy-3,3-dimethyl-3,4-dihydro-isoquinolin-1-yl)-chromen-2-one
Target: TRP/TRPV Channel
LCL161
Cat.No: T2080
Synonym:
Target: IAP
XMD17-109
Cat.No: T1842
Synonym: XMD17 109,ERK5-IN-1
Target: ERK
ORM-15341
Cat.No: T12323
Synonym:
Target: Androgen Receptor
KY1220
Cat.No: T15677
Synonym:
Target: Wnt/beta-catenin
EMPA
Cat.No: T11186
Synonym:
Target: OX Receptor
Fz7-21
Cat.No: TP1263
Synonym: (Ac)-LPSDDLEFWCHVMY-NH2
Target: Wnt/beta-catenin
2-PCCA hydrochloride
Cat.No: T80666
Synonym: 2-PCCA hydrochloride(1609624-97-6 Free base)
Target: cAMP
M62812
Cat.No: T37292
Synonym:
Target: TLR
ML224
Cat.No: T16106
Synonym: NCGC00242364,ANTAG3
Target: TSH Receptor
SNC 80
Cat.No: T8414
Synonym: Snc-80,SNC80,NIH 10815
Target: Opioid Receptor
Teriparatide acetate
Cat.No: T21460
Synonym: hPTH 1-34 (acetate salt),Parathar acetate,Forteo,醋酸立特帕肽
Target: Others
PF-915275
Cat.No: T16510
Synonym:
Target: Dehydrogenase
Pyr10
Cat.No: T16686
Synonym:
Target: TRP/TRPV Channel
NSC-87877 disodium
Cat.No: T6911
Synonym: NSC87877
Target: Apoptosis, Phosphatase
Acetohexamide
Cat.No: T0816
Synonym: Acetohexamid,醋磺环已脲,Dymelor,醋磺己脲,Gamadiabet
Target: Potassium Channel, NADPH
Flindokalner
Cat.No: T15286
Synonym: BMS-204352
Target: Potassium Channel
JLK6
Cat.No: T21890
Synonym:
Target: Gamma-secretase
Linrodostat
Cat.No: T4532
Synonym: BMS-986205
Target: IDO, Indoleamine 2,3-Dioxygenase (IDO)
PU02
Cat.No: T8445
Synonym: PU-02,6-[(1-Naphthalenylmethyl)thio]-9H-purine
Target: Apoptosis, 5-HT Receptor
GSK717
Cat.No: T38361
Synonym:
Target: IL Receptor, NOD
MK-4101
Cat.No: T6891
Synonym:
Target: Apoptosis, Hedgehog/Smoothened, Smo
DSR-6434
Cat.No: T11108
Synonym:
Target: TLR
(1R,2R)-2-PCCA hydrochloride
Cat.No: T13423
Synonym: (1R,2R)-2-PCCA(hydrochloride)
Target: Others
Cat. No. Product Name Target Signaling Pathways
T3673 Mollugin

大叶茜草素,Rubimaillin

HER; JAK Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
Mollugin (Rubimaillin) 是Rubia cordifolia L.中主要的生物活性成分。它能通过 p38-Smad 信号通路增强 BMP-2 的成骨作用。它通过抑制 TNF-α 诱导的 NF-κB 激活起抗癌疗效。
T1537 Rapamycin

Sirolimus,AY 22989,雷帕霉素,NSC-2260804

Others; Endogenous Metabolite; Antibiotic; mTOR; Autophagy; Antifungal Autophagy; Metabolism; Microbiology/Virology; Others; PI3K/Akt/mTOR signaling
Rapamycin (AY 22989) 属于大环内酯类天然产物,是一种 mTOR 抑制剂,具有特异性(HEK293 细胞:IC50=0.1 nM)。Rapamycin 具有免疫抑制活性,并能诱导自噬。
T1062 Capsaicin

Qutenza,8-Methyl-N-vanillyl-trans-6-nonenamide,天然辣椒素,Vanilloid,辣椒素,(E)-Capsaicin,Zostrix

Apoptosis; TRP/TRPV Channel; Autophagy Apoptosis; Autophagy; Membrane transporter/Ion channel
Capsaicin ((E)-Capsaicin) 属于天然产物,提取自辣椒,是一种 TRPV1 激动剂 (EC50=0.29 μM)。Capsaicin 具有抗肿瘤、抗炎、抗氧化、神经保护等活性。
T19122 3-Methylvaleric Acid

Others; Endogenous Metabolite Metabolism; Others
3-Methylvaleric Acid 是一种食用级香料,存在于烟草中。3-Methylvaleric Acid 可增强 CHO-K1细胞和HEK293细胞中的细胞内cAMP 积累和CRE-荧光素酶活性。
TN1092 O-Nornuciferine

Potassium Channel; HER Angiogenesis; JAK/STAT signaling; Membrane transporter/Ion channel; Tyrosine Kinase/Adaptors
O-Noruciferine 是分离自荷叶的卟啉型生物碱,是有效的 hERG 通道抑制剂。
TN1018 Angeloylgomisin H

当归酰戈米辛 H,当归酰戈米辛H

PPAR DNA Damage/DNA Repair; Metabolism
Angeloylgomisin H 是从五味子中提取的一种木脂素类天然产物。它通过激活PPAR-γ来改善胰岛素刺激的葡萄糖摄取潜力。
T8190 5-Hydroxyflavone

Others Others
5-Hydroxyflavone 是类黄酮配体,对 FaDU,MCF-7,U87,MDA-MB-435S,RPE-1 和 HEK293 细胞没有细胞毒性。
T3880 Silydianin

水飞蓟宁,Silidianin

Phosphatase Metabolism
Silydianin (Silidianin) 是一种水飞蓟的活性成分,具有抗胶原酶和抗弹性酶作用,对氧化产物的体外产生和释放具有抑制作用 。它是一种天然蛋白酪氨酸磷酸酶 1B 抑制剂,其IC50=17.38 μM。
T16885 Simvastatin acid ammonium

辛伐他汀铵盐,Tenivastatin ammonium

Others Others
Simvastatin ammonium is an active metabolite of simvastatin lactone mediated. Simvastatin ammonium reduces indoxyl sulfate-mediated reactive oxygen species and modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 ge
T35532 Galegine hydrochloride

Others Others
Galegine hydrochloride, a guanidine derivative derived from G. officinalis, plays a role in inducing weight loss in mice and has contributed to the development of biguanides, including metformin and phenformin. This compound stimulates AMPK activation in 3T3-L1 adipocytes, L6 myotubes, H4IIE rat hepatoma, and HEK293 human kidney cell lines. Additionally, galegine hydrochloride exhibits antibacterial properties, particularly demonstrating a minimum inhibitory concentration of 4 mg/L against Staph...

天然产物

Mollugin
Cat.No: T3673
Synonym: 大叶茜草素,Rubimaillin
Target: HER, JAK
Rapamycin
Cat.No: T1537
Synonym: Sirolimus,AY 22989,雷帕霉素,NSC-2260804
Target: Others, Endogenous Metabolite, Antibiotic, mTOR, Autophagy, Antifungal
Capsaicin
Cat.No: T1062
Synonym: Qutenza,8-Methyl-N-vanillyl-trans-6-nonenamide,天然辣椒素,Vanilloid,辣椒素,(E)-Capsaicin,Zostrix
Target: Apoptosis, TRP/TRPV Channel, Autophagy
3-Methylvaleric Acid
Cat.No: T19122
Synonym:
Target: Others, Endogenous Metabolite
O-Nornuciferine
Cat.No: TN1092
Synonym:
Target: Potassium Channel, HER
Angeloylgomisin H
Cat.No: TN1018
Synonym: 当归酰戈米辛 H,当归酰戈米辛H
Target: PPAR
5-Hydroxyflavone
Cat.No: T8190
Synonym:
Target: Others
Silydianin
Cat.No: T3880
Synonym: 水飞蓟宁,Silidianin
Target: Phosphatase
Simvastatin acid ammonium
Cat.No: T16885
Synonym: 辛伐他汀铵盐,Tenivastatin ammonium
Target: Others
Galegine hydrochloride
Cat.No: T35532
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPY-02792 GDNF Protein, Human, Recombinant (HEK293)

HSCR3,ATF2,HFB1-GDNF,ATF1,glial cell derived neurotrophic fa...

Human HEK293 Cells
GDNF Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 15.1 kDa and the accession number is P39905-2.
TMPY-06985 NGF Protein, Human, Recombinant (HEK293)

NGFB,神经生长因子,Beta-NGF,HSAN5,β-NGF,nerve growth factor (beta p...

Human HEK293 Cells
NGF Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 24.8 kDa. and the accession number is P01138.
TMPY-01920 BAFF/TNFSF13B Protein, Human, Recombinant (HEK293)

BAFF,THANK,BLYS,TNFSF20,CD257,tumor necrosis factor (ligand)...

Human HEK293 Cells
BAFF/TNFSF13B Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 17 kDa and the accession number is Q9Y275-1.
TMPY-01191 CD3 epsilon/CD3e Protein, Human, Recombinant (HEK293, His)

IMD18,CD3 epsilon,T3E,CD3 ε,CD3e molecule, ε (CD3-TCR comple...

Human HEK293 Cells
CD3 epsilon/CD3e Protein, Human, Recombinant (HEK293,His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.2 kDa and the accession number is P07766.
TMPY-04090 Influenza A H7N9 (A/Shanghai/2/2013) Hemagglutinin/HA Protein (HEK293, His)

Harvey rat sarcoma viral oncogene homolog

H7N9 HEK293 Cells
Influenza A H7N9 (A/Shanghai/2/2013) Hemagglutinin/HA Protein (HEK293, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.6 kDa.
TMPY-01501 Influenza A H1N1 (A/Puerto Rico/8/1934) Hemagglutinin/HA Protein (HEK293, His)

Harvey rat sarcoma viral oncogene homolog

H1N1 HEK293 Cells
Influenza A H1N1 (A/Puerto Rico/8/1934) Hemagglutinin/HA Protein (HEK293, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59 kDa and the accession number is P03452.
TMPJ-00895 SCF Protein, Rat, Recombinant (HEK293, His)

steel factor,Mast cell growth factor,SLF,MGFSHEP7,SCFStem ce...

Rat HEK293 Cells
SCF/C-kit ligand is the ligand of the tyrosine-kinase receptor encoded by the KIT locus. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. In phase I/II...
TMPJ-01022 SUMO3 Protein, Human, Recombinant (HEK293, His)

SMT3 homolog 1,Smt3A,Small ubiquitin-related modifier 3,Ubiq...

Human HEK293 Cells
Small ubiquitin-like modifier (SUMO), also known as SUMO homologue and SMT3, is a member of the superfamily of ubiquitin-like polypeptides that become covalently attached to various intracellular target proteins as a way to alter their function, location, and/or half-life. Small ubiquitin-like modifiers include SUMO1, SUMO2, SUMO3, and SUMO4. Except for SUMO4, all other SUMOs are ubiquitously expressed, including in the brain. In human, SUMO2 and SUMO3 are two highly homologous proteins, collect...
TMPY-02024 L-selectin Protein, Human, Recombinant (HEK293,His)

LECAM1,TQ1,CD62L,LYAM1,LSEL,LNHR,LAM1,selectin L,PLNHR,LEU8

Human HEK293 Cells
L-selectin Protein, Human, Recombinant (HEK293,His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.5 kDa and the accession number is P14151-1.
TMPH-00343 Angiopoietin-1 Protein, Canine, Recombinant (HEK293, His)

Angiopoietin-1,ANG-1,ANGPT1

Canine HEK293 Cells
Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Mediates blood vessel maturation/stability. It may play an important role in the heart early development. Angiopoietin-1 Protein, Canine, Recombinant (HEK293, His) is expressed in HEK293 mammalian cells wi...
TMPY-06314 MMP-10 Protein, Human, Recombinant (HEK293, His)

STMY2,matrix metallopeptidase 10,SL-2

Human HEK293 Cells
MMP-10 Protein, Human, Recombinant (HEK293, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44.38 kDa and the accession number is P09238.
TMPH-01683 Tau-F Protein, Human, Recombinant (HEK293, His)

Microtubule-associated protein tau,Paired helical filament-t...

Human HEK293 Cells
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the ...
TMPJ-01163 CTGF/CCN2 Protein, Human, Recombinant (HEK293, His)

CTGF,Connective tissue growth factor

Human HEK293 Cells
Connective Tissue Growth Factor (CTGF), also known as CCN2, is a member of the CCN (CYR61/CTGF/NOV) family of secreted matricellular proteins. Like other CCN proteins, mature human CTGF consists of IGF-binding protein domain, a vWF-C domain, a TSP-1 domain, and a cysteine knot heparin-binding domain. CTGF has various biological functions, including cell adhesion, migration, proliferation, differentiation, and ECM production, and participates in the development of many organs under normal physio...
TMPH-00743 PhoP Protein, E. coli, Recombinant (HEK293, His & Myc)

Transcriptional regulatory protein PhoP,phoP

E. coli HEK293 Cells
Member of the two-component regulatory system PhoP/PhoQ involved in adaptation to low Mg(2+) environments and the control of acid resistance genes. In low periplasmic Mg(2+), PhoQ phosphorylates PhoP, resulting in the expression of PhoP-activated genes (PAG) and repression of PhoP-repressed genes (PRG). In high periplasmic Mg(2+), PhoQ dephosphorylates phospho-PhoP, resulting in the repression of PAG and may lead to expression of some PRG. Mediates magnesium influx to the cytosol by activation o...
TMPY-02167 Complement Factor D/CFD Protein, Mouse, Recombinant (His,HEK293)

DF,Adn,complement factor D (adipsin)

Mouse HEK293 Cells
Complement Factor D/CFD Protein, Mouse, Recombinant (His,HEK293) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.4 kDa and the accession number is P03953-2.
TMPJ-00716 Cerberus 1/CER1 Protein, Human, Recombinant (HEK293, His)

DAN Domain Family Member 4,Cerberus,Cerberus-Related Protein...

Human HEK293 Cells
Cerberus 1 is a secreted glycoprotein that forms disulfide-linked homodimers. It is a cytokine member of the DAN domain family of BMP antagonists that includes DAN (DAND1), Gremlin/Drm (DAND2), PRDC (Protein Related to Dan and Cerberus, DAND3), and COCO/Dante (DAND5). DAN family members contain a cysteine knot domain that is homologous to that found in other TGF-beta superfamily ligands. At the onset of gastrulation, Cerberus 1 is transiently expressed in anterior endodermal structures in respon...
TMPY-05661 SARS-CoV-2 Spike S1 Protein (HEK293, His)

HEK293 Cells
SARS-CoV-2 Spike S1 Protein (HEK293, His) is expressed in HEK293 mammalian cells with His tag. The accession number is A0A6G7K2L4.
TMPJ-00386 ACE2/ACEH Protein, Human, Recombinant (HEK293, His & Avi), Biotinylated

Metalloprotease MPROT15,ACEH,Angiotensin-Converting Enzyme H...

Human HEK293 Cells
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate...
TMPY-05683 SARS-CoV-2 Spike RBD Protein (HEK293, His), Biotinylated

SARS-CoV-2 HEK293 Cells
SARS-CoV-2 Spike RBD Protein (HEK293, His), Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.54 kDa and the accession number is A0A6G7K2L4.
TMPY-05719 SARS-CoV-2 Spike RBD Protein (HEK293, Avi & His), Biotinylated

SARS-CoV-2 HEK293 Cells
SARS-CoV-2 Spike RBD Protein (HEK293, Avi & His), Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 28.36 kDa and the accession number is A0A6G7K2L4.
TMPY-03800 Influenza A H7N9 (A/Shanghai/1/2013) Hemagglutinin/HA Protein (HEK293, His)

Harvey rat sarcoma viral oncogene homolog

H7N9 HEK293 Cells
Influenza A H7N9 (A/Shanghai/1/2013) Hemagglutinin/HA Protein (HEK293, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.7 kDa.
TMPY-05932 Influenza A H1N1 (A/swine/Canada/01093/2006) Neuraminidase/NA Protein (HEK293, His)

NA Protein

H1N1 HEK293 Cells
Influenza A H1N1 (A/swine/Canada/01093/2006) Neuraminidase/NA Protein (HEK293, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.2 kDa and the accession number is A0A0G3XQY1.
TMPY-03840 Influenza A H7N9 (A/Pigeon/Shanghai/S1069/2013) Hemagglutinin/HA Protein (HEK293, His)

Harvey rat sarcoma viral oncogene homolog

H7N9 HEK293 Cells
Influenza A H7N9 (A/Pigeon/Shanghai/S1069/2013) Hemagglutinin/HA Protein (HEK293, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.7 kDa.
TMPY-00549 Influenza A H5N1 (A/common magpie/Hong Kong/5052/2007) Hemagglutinin/HA Protein (HEK293, His)

Harvey rat sarcoma viral oncogene homolog

H5N1 HEK293 Cells
Influenza A H5N1 (A/common magpie/Hong Kong/5052/2007) Hemagglutinin/HA Protein (HEK293, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60 kDa and the accession number is B7NWR4.
TMPY-00595 Influenza A H5N1 (A/common magpie/Hong Kong/5052/2007) Hemagglutinin/HA1 Protein (HEK293, His)

Harvey rat sarcoma viral oncogene homolog

H5N1 HEK293 Cells
Influenza A H5N1 (A/common magpie/Hong Kong/5052/2007) Hemagglutinin/HA1 Protein (HEK293, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38 kDa and the accession number is B7NWR4.
TMPY-06987 Wnt Surrogate/Wnt3a Protein, Recombinant

Wnt 3a,wnt3a,Wnt-3a

Human HEK293 Cells
Wnt Surrogate/Wnt3a Protein, Recombinant is expressed in HEK293 mammalian cells with hFc tag.
TMPY-00608 TGF beta 1 Protein, Rat/Mouse, Recombinant

transforming growth factor, beta 1,transforming growth facto...

Mouse,Rat HEK293 Cells
TGF beta 1 Protein, Rat/Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 12.8 kDa.
TMPY-05072 IgE Fc Protein, Human, Recombinant (His)

Human HEK293 Cells
IgE Fc Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.4 kDa.
TMPY-04832 OX40L/TNFSF4 Protein, Human, Recombinant (hFc)

CD252,OX-40L,tumor necrosis factor (ligand) superfamily, mem...

Human HEK293 Cells
OX40L/TNFSF4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.6 kDa.
TMPY-03890 CD81 Protein, Human, Recombinant

S5.7,CVID6,TSPAN28,TAPA1,CD81 molecule

Human HEK293 Cells
CD81 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 9.9 kDa and the accession number is A0A024RCB7.
TMPY-04018 LRG1 Protein, Human, Recombinant

HMFT1766,leucine-rich α-2-glycoprotein 1,LRG,leucine-rich al...

Human HEK293 Cells
LRG1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 35.1 kDa and the accession number is AAH34389.1.
TMPY-02694 IgG2a Protein, Mouse, Recombinant

IgG2a-Fc,Igh-1,1816O9Rik

Mouse HEK293 Cells
IgG2a Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.4 kDa and the accession number is P01863.
TMPY-05566 Siglec-2/CD22 Protein, Human, Recombinant (His, Solution)

CD22 molecule,SIGLEC-2,SIGLEC2

Human HEK293 Cells
Siglec-2/CD22 Protein, Human, Recombinant (His, Solution) is expressed in HEK293 mammalian cells with His tag. The accession number is P20273-1.
TMPY-05573 CD38 Protein, Human, Recombinant (His), PE conjugated

T10,ADPRC1,ADPRC 1,CD38 molecule

Human HEK293 Cells
CD38 Protein, Human, Recombinant (His), PE conjugated is expressed in HEK293 mammalian cells with His tag. The accession number is NP_001766.2.
TMPY-03776 CD25/IL2R alpha Protein, Cynomolgus, Recombinant

interleukin 2 receptor, α,interleukin 2 receptor, alpha,CD25...

Cynomolgus HEK293 Cells
CD25/IL2R alpha Protein, Cynomolgus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 22.4 kDa and the accession number is H6WS54.
TMPY-05191 CD47 Protein, Human, Recombinant, Biotinylated

CD47 molecule,MER6,OA3,IAP

Human HEK293 Cells
CD47 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.
TMPY-01477 MMP-2 Protein, Human, Recombinant

TBE-1,MMP-II,matrix metallopeptidase 2,MONA,CLG4,CLG4A,MMP-2

Human HEK293 Cells
MMP-2 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 72 kDa and the accession number is A0A024R6R4.
TMPY-02693 IgG4 Protein, Human, Recombinant (S108P)

IGHG4,IgG4 Fc

Human HEK293 Cells
IgG4 Protein, Human, Recombinant (S108P) is expressed in HEK293 mammalian cells. The predicted molecular weight is 25.5 kDa and the accession number is P01861.
TMPY-03858 GM-CSF/CSF2 Protein, Human, Recombinant

CSF2,colony stimulating factor 2 (granulocyte-macrophage),GM...

Human HEK293 Cells
GM-CSF/CSF2 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is P04141.
TMPY-05568 BCMA/TNFRSF17 Protein, Human (His & hFc), PE conjugated

BCMA,TNFRSF13A,tumor necrosis factor receptor superfamily me...

Human HEK293 Cells
BCMA/TNFRSF17 Protein, Human (His & hFc), PE conjugated is expressed in HEK293 mammalian cells with His and Fc tag. The accession number is NP_001183.2.
TMPY-04683 CD47 Protein, Human, Recombinant

MER6,CD47 molecule,OA3,IAP

Human HEK293 Cells
CD47 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.
TMPY-03516 IL-12B Protein, Mouse, Recombinant

Il-12p40,interleukin 12B,Il-12b,Il12p40,p40

Mouse HEK293 Cells
IL-12B Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 36.6 kDa and the accession number is P43432.
TMPY-05084 Fc epsilon RI Protein, Human, Recombinant

alpha polypeptide,FcERI,α polypeptide,Fc fragment of IgE, hi...

Human HEK293 Cells
Fc epsilon RI Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 21 kDa and the accession number is P12319.
TMPY-01884 MMP-8 Protein, Human, Recombinant

CLG1,HNC,PMNL-CL,matrix metallopeptidase 8,MMP-8

Human HEK293 Cells
MMP-8 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 52 kDa and the accession number is P22894.
TMPY-00860 CD122/IL2RB Protein, Human, Recombinant

interleukin 2 receptor, β,interleukin 2 receptor, beta,CD122...

Human HEK293 Cells
CD122/IL2RB Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 25.2 kDa and the accession number is P14784.
TMPY-04824 CTLA-4 Protein, Human, Recombinant

CTLA-4,GSE,IDDM12,CELIAC3,ALPS5,CD,GRD4,cytotoxic T-lymphocy...

Human HEK293 Cells
CTLA-4 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 13.5 kDa and the accession number is P16410-1.
TMPY-05636 G-CSF Protein, Mouse, Recombinant

G-CSF,MGI-IG,Csfg,集落刺激因子,colony stimulating factor 3 (granul...

Mouse HEK293 Cells
G-CSF Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 19 kDa and the accession number is P09920.
TMPY-00246 HER3/ERBB3 Protein, Rhesus, Recombinant

erb-b2 receptor tyrosine kinase 3

Rhesus HEK293 Cells
HER3/ERBB3 Protein, Rhesus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 69.5 kDa and the accession number is XP_001113953.2.
TMPY-04211 Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His)

transforming growth factor, β1,TGF β1,transforming growth fa...

Cynomolgus HEK293 Cells
Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa.
TMPY-00399 HER3/ERBB3 Protein, Human, Recombinant

LCCS2,c-erbB-3,HER3,p180-ErbB3,erbB3-S,MDA-BF-1,erb-b2 recep...

Human HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 69.3 kDa and the accession number is P21860-1.
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重组蛋白

GDNF Protein, Human, Recombinant (HEK293)
Cat.No: TMPY-02792
Species: Human
Expression System: HEK293 Cells
NGF Protein, Human, Recombinant (HEK293)
Cat.No: TMPY-06985
Species: Human
Expression System: HEK293 Cells
BAFF/TNFSF13B Protein, Human, Recombinant (HEK293)
Cat.No: TMPY-01920
Species: Human
Expression System: HEK293 Cells
CD3 epsilon/CD3e Protein, Human, Recombinant (HEK293, His)
Cat.No: TMPY-01191
Species: Human
Expression System: HEK293 Cells
Influenza A H7N9 (A/Shanghai/2/2013) Hemagglutinin/HA Protein (HEK293, His)
Cat.No: TMPY-04090
Species: H7N9
Expression System: HEK293 Cells
Influenza A H1N1 (A/Puerto Rico/8/1934) Hemagglutinin/HA Protein (HEK293, His)
Cat.No: TMPY-01501
Species: H1N1
Expression System: HEK293 Cells
SCF Protein, Rat, Recombinant (HEK293, His)
Cat.No: TMPJ-00895
Species: Rat
Expression System: HEK293 Cells
SUMO3 Protein, Human, Recombinant (HEK293, His)
Cat.No: TMPJ-01022
Species: Human
Expression System: HEK293 Cells
L-selectin Protein, Human, Recombinant (HEK293,His)
Cat.No: TMPY-02024
Species: Human
Expression System: HEK293 Cells
Angiopoietin-1 Protein, Canine, Recombinant (HEK293, His)
Cat.No: TMPH-00343
Species: Canine
Expression System: HEK293 Cells
MMP-10 Protein, Human, Recombinant (HEK293, His)
Cat.No: TMPY-06314
Species: Human
Expression System: HEK293 Cells
Tau-F Protein, Human, Recombinant (HEK293, His)
Cat.No: TMPH-01683
Species: Human
Expression System: HEK293 Cells
CTGF/CCN2 Protein, Human, Recombinant (HEK293, His)
Cat.No: TMPJ-01163
Species: Human
Expression System: HEK293 Cells
PhoP Protein, E. coli, Recombinant (HEK293, His & Myc)
Cat.No: TMPH-00743
Species: E. coli
Expression System: HEK293 Cells
Complement Factor D/CFD Protein, Mouse, Recombinant (His,HEK293)
Cat.No: TMPY-02167
Species: Mouse
Expression System: HEK293 Cells
Cerberus 1/CER1 Protein, Human, Recombinant (HEK293, His)
Cat.No: TMPJ-00716
Species: Human
Expression System: HEK293 Cells
SARS-CoV-2 Spike S1 Protein (HEK293, His)
Cat.No: TMPY-05661
Species:
Expression System: HEK293 Cells
ACE2/ACEH Protein, Human, Recombinant (HEK293, His & Avi), Biotinylated
Cat.No: TMPJ-00386
Species: Human
Expression System: HEK293 Cells
SARS-CoV-2 Spike RBD Protein (HEK293, His), Biotinylated
Cat.No: TMPY-05683
Species: SARS-CoV-2
Expression System: HEK293 Cells
SARS-CoV-2 Spike RBD Protein (HEK293, Avi & His), Biotinylated
Cat.No: TMPY-05719
Species: SARS-CoV-2
Expression System: HEK293 Cells
Influenza A H7N9 (A/Shanghai/1/2013) Hemagglutinin/HA Protein (HEK293, His)
Cat.No: TMPY-03800
Species: H7N9
Expression System: HEK293 Cells
Influenza A H1N1 (A/swine/Canada/01093/2006) Neuraminidase/NA Protein (HEK293, His)
Cat.No: TMPY-05932
Species: H1N1
Expression System: HEK293 Cells
Influenza A H7N9 (A/Pigeon/Shanghai/S1069/2013) Hemagglutinin/HA Protein (HEK293, His)
Cat.No: TMPY-03840
Species: H7N9
Expression System: HEK293 Cells
Influenza A H5N1 (A/common magpie/Hong Kong/5052/2007) Hemagglutinin/HA Protein (HEK293, His)
Cat.No: TMPY-00549
Species: H5N1
Expression System: HEK293 Cells
Influenza A H5N1 (A/common magpie/Hong Kong/5052/2007) Hemagglutinin/HA1 Protein (HEK293, His)
Cat.No: TMPY-00595
Species: H5N1
Expression System: HEK293 Cells
Wnt Surrogate/Wnt3a Protein, Recombinant
Cat.No: TMPY-06987
Species: Human
Expression System: HEK293 Cells
TGF beta 1 Protein, Rat/Mouse, Recombinant
Cat.No: TMPY-00608
Species: Mouse,Rat
Expression System: HEK293 Cells
IgE Fc Protein, Human, Recombinant (His)
Cat.No: TMPY-05072
Species: Human
Expression System: HEK293 Cells
OX40L/TNFSF4 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04832
Species: Human
Expression System: HEK293 Cells
CD81 Protein, Human, Recombinant
Cat.No: TMPY-03890
Species: Human
Expression System: HEK293 Cells
LRG1 Protein, Human, Recombinant
Cat.No: TMPY-04018
Species: Human
Expression System: HEK293 Cells
IgG2a Protein, Mouse, Recombinant
Cat.No: TMPY-02694
Species: Mouse
Expression System: HEK293 Cells
Siglec-2/CD22 Protein, Human, Recombinant (His, Solution)
Cat.No: TMPY-05566
Species: Human
Expression System: HEK293 Cells
CD38 Protein, Human, Recombinant (His), PE conjugated
Cat.No: TMPY-05573
Species: Human
Expression System: HEK293 Cells
CD25/IL2R alpha Protein, Cynomolgus, Recombinant
Cat.No: TMPY-03776
Species: Cynomolgus
Expression System: HEK293 Cells
CD47 Protein, Human, Recombinant, Biotinylated
Cat.No: TMPY-05191
Species: Human
Expression System: HEK293 Cells
MMP-2 Protein, Human, Recombinant
Cat.No: TMPY-01477
Species: Human
Expression System: HEK293 Cells
IgG4 Protein, Human, Recombinant (S108P)
Cat.No: TMPY-02693
Species: Human
Expression System: HEK293 Cells
GM-CSF/CSF2 Protein, Human, Recombinant
Cat.No: TMPY-03858
Species: Human
Expression System: HEK293 Cells
BCMA/TNFRSF17 Protein, Human (His & hFc), PE conjugated
Cat.No: TMPY-05568
Species: Human
Expression System: HEK293 Cells
CD47 Protein, Human, Recombinant
Cat.No: TMPY-04683
Species: Human
Expression System: HEK293 Cells
IL-12B Protein, Mouse, Recombinant
Cat.No: TMPY-03516
Species: Mouse
Expression System: HEK293 Cells
Fc epsilon RI Protein, Human, Recombinant
Cat.No: TMPY-05084
Species: Human
Expression System: HEK293 Cells
MMP-8 Protein, Human, Recombinant
Cat.No: TMPY-01884
Species: Human
Expression System: HEK293 Cells
CD122/IL2RB Protein, Human, Recombinant
Cat.No: TMPY-00860
Species: Human
Expression System: HEK293 Cells
CTLA-4 Protein, Human, Recombinant
Cat.No: TMPY-04824
Species: Human
Expression System: HEK293 Cells
G-CSF Protein, Mouse, Recombinant
Cat.No: TMPY-05636
Species: Mouse
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Rhesus, Recombinant
Cat.No: TMPY-00246
Species: Rhesus
Expression System: HEK293 Cells
Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-04211
Species: Cynomolgus
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant
Cat.No: TMPY-00399
Species: Human
Expression System: HEK293 Cells
--------- 更多 ---------
Cat. No. Product Name Target Signaling Pathways
T12691 Rapamycin-d3

AY-22989-d3,Sirolimus-d3

Others Others
Rapamycin-d3 is the deuterium labeled Rapamycin. Rapamycin is a potent and specific inhibitor of mTOR(IC50 of 0.1 nM in HEK293 cells).

同位素标记化合物

Rapamycin-d3
Cat.No: T12691
Synonym: AY-22989-d3,Sirolimus-d3
Target: Others
TargetMol Loading
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