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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T9766 |
GW590735
|
PPAR | DNA Damage/DNA Repair; Metabolism |
GW590735 是一种有效的选择性 PPARα 激动剂,对 PPARα 的 EC50 为 4 nM,比 PPARδ 和 PPARγ 的选择性至少高 500 倍。 GW590735 可用于血脂异常研究。 | |||
T64006 |
Lipid-lowering agent-1
|
Others | Others |
Lipid-lowering agent-1 是有效的降脂剂,能够明显抑制低密度脂蛋白胆固醇 (LDLC) 和促进高密度脂蛋白胆固醇 (HDLC) 产生的药理作用。Lipid-lowering agent-1 能够明显降低高脂饮食大鼠的脂肪。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-01052 |
DYNLL1 Protein, Human, Recombinant (His)
DNCL1,PIN,DLC8,Protein Inhibitor of Neuronal Nitric Oxide Sy... |
Human | E. coli |
Human Dynein Cytoplasmic Light Chain 1 (DYNLL1) has been identified as a protein that interacts with NOS1, leading to NOS1 inhibition. NOS1 dimer is destabilized after binding DYNLL1 a conformation necessary activity, and it regulate numerous biologic processes throughits effects on nitric oxide synthase activity. DYNLL1 is widely expressed, with higher expression in testis and moderate expression in brain. |